Friday, March 17, 2023


China took down data on potential insight into origins of Covid-19, says WHO

China should have shared the data three years ago when the pandemic had begun in 2020, the global health body said.
Director-General of the World Health Organization Tedros Adhanom Ghebreyesus. | Screengrab via @DrTedros / Twitter

The World Health Organization said on Friday that China took down data related to a research that might have provided more insight into the origins of the Covid-19 virus.

“Last Sunday, WHO was made aware of data published on the GISAID [Global Initiative on Sharing Avian Influenza Data] database in late January, and taken down again recently,” Director-General of the World Health Organization Tedros Adhanom Ghebreyesus said. “The data, from the Chinese Center for Disease Control and Prevention, relates to samples taken at the Huanan market in Wuhan, in 2020.”

He added that scientists from a number of countries downloaded the data and analysed it while it was still online.

“As soon as we became aware of this data, we contacted the Chinese CDC [Centre for Disease Control] and urged them to share it with WHO and the international scientific community so it can be analysed,” Ghebreyesus said.

The World Health Organization said that China should have shared the data three years ago when the pandemic had begun in 2020. “Understanding how the pandemic began remains both a moral and scientific imperative,” WHO said.

The global health body also said that Covid-19 could soon transition to a point where it is similar to flu.

“I think we’re coming to that point where we can look at Covid-19 in the same way we look at seasonal influenza, a threat to health, a virus that will continue to kill, but a virus that is not disrupting our society or disrupting our hospital system” WHO said.

Meanwhile, India has reported an increase in the number of Covid-19 cases this week along with other infleunza cases. On Saturday, India recorded more than 800 cases of coronavirus in a single day for the first time after 126 days. The number of active cases of Covid-19 in the country rose to 5,389 on Saturday.

On Thursday, the Centre had asked Tamil Nadu, Telangana, Kerala, Karnataka, Maharashtra and Gujarat – states which have been recording most of the new cases – to ramp up testing, monitor new clusters and send samples of international travellers, reported The Indian Express.

WHO accuses China of hiding data that may link COVID’s origins to animals

By Benjamin Mueller
Updated March 18, 2023 — 

The World Health Organisation rebuked Chinese officials for withholding research that may link COVID-19’s origin to wild animals, asking why the data had not been made available three years ago and why it is now missing.

Before the Chinese data disappeared, an international team of virus experts downloaded and began analysing the research, which appeared online in January. They say it supports the idea that the pandemic could have begun when illegally traded raccoon dogs infected humans at a Wuhan seafood market.


A security guard waves for journalists to clear the road after a convoy carrying the World Health Organisation team entered the Huanan Seafood Market in January 2021.CREDIT:AP

But the gene sequences were removed from a scientific database once the experts offered to collaborate on the analysis with their Chinese counterparts.

“These data could have — and should have — been shared three years ago,” WHO Director-General Tedros Adhanom Ghebreyesus said. The missing evidence now “needs to be shared with the international community immediately.”

According to the experts who are reviewing it, the research offers evidence that raccoon dogs — foxlike animals known to spread coronaviruses — had left behind DNA in the same place in the Wuhan market that genetic signatures of the new coronavirus also were discovered.

To some experts, that finding suggests that the animals may have been infected and may have transmitted the virus to humans.



A security guard sits outside the closed Huanan Seafood Wholesale Market, CREDIT:GETTY

With huge amounts of genetic information drawn from swabs of animal cages, carts and other surfaces at the Wuhan market in early 2020, the genetic data had been the focus of restless anticipation among virus experts since they learned of it a year ago in a paper by Chinese scientists.

A French biologist discovered the genetic sequences in the database last week, and she and a team of colleagues began mining them for clues about the origins of the pandemic.


That team has not yet released a paper outlining the findings. But the researchers delivered an analysis of the material to a WHO advisory group studying COVID’s origins this week in a meeting that also included a presentation by Chinese researchers regarding the same data.

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Coronavirus pandemic
New data links COVID’s origins to raccoon dogs at Wuhan market

The analysis seemed to clash with earlier contentions by Chinese scientists that samples taken in the market that were positive for the coronavirus had been ferried in by sick people alone, said Sarah Cobey, an epidemiologist and evolutionary biologist at the University of Chicago who was not involved in recent research.

“It’s just very unlikely to be seeing this much animal DNA, especially raccoon dog DNA, mixed in with viral samples, if it’s simply mostly human contamination,” Cobey said.

Questions remain about how the samples were collected, what precisely they contained and why the evidence had disappeared. In light of the ambiguities, many scientists reacted cautiously, saying that it was difficult to assess the research without seeing a complete report.



The idea that a lab accident could have accidentally set off the pandemic has become the focus of renewed interest in recent weeks, thanks in part to a fresh intelligence assessment from the Department of Energy and hearings held by the new Republican House leadership.

But a number of virus experts not involved with the latest analysis said that what was known about the swabs gathered in the market buttressed the case that animals sold there had sparked the pandemic.


A convoy of vehicles carrying the World Health Organisation team enters the interior of the Huanan Seafood Market in January 2021.CREDIT:AP

“It’s exactly what you’d expect if the virus was emerging from an intermediate or multiple intermediate hosts in the market,” Cobey said. “I think ecologically, this is close to a closed case.”

Cobey was one of 18 scientists who signed an influential letter in the journal Science in May 2021 urging serious consideration of a scenario in which the virus could have spilled out of a laboratory in Wuhan.

On Friday, she said lab leaks continued to pose enormous risks and that more oversight of research into dangerous pathogens was needed. But Cobey added that an accumulation of evidence — relating to the clustering of human cases around the Wuhan market, the genetic diversity of viruses there and now the raccoon dog data — strengthened the case for a market origin.

The new genetic data does not appear to prove that a raccoon dog was infected with the coronavirus. Even if it had been, the possibility would remain that another animal could have passed that virus to people, or even that someone infected with the virus could have transmitted it to a raccoon dog.

Some scientists stressed those points Friday, saying that the new genetic data did not appreciably shift the discussion about the pandemic’s origins.

“We know it’s a promiscuous virus that infects a bunch of species,” said David Fisman, an epidemiologist at the University of Toronto, who also signed the May 2021 letter in Science.

Chinese scientists had released a study in February 2022 looking at the market samples. Some scientists speculated that the Chinese researchers might have posted the data in January because they were required to make them available as part of a review of their study by a scientific journal.

The Chinese study had suggested that samples that were positive for the virus had come from infected people, rather than from animals sold in the market. That fit with a narrative long promulgated by Chinese officials: that the virus sprang not only from outside the market but from outside the country altogether.

Raccoon dogs are related to foxes and are known to be able to transmit the coronavirus.

But the Chinese report had left clues that viral material at the market had been jumbled together with genetic material from animals. And scientists said the new analysis by the international team illustrated an even stronger link with animals.

“Scientifically, it doesn’t prove that raccoon dogs were the source, but it sure smells like infected raccoon dogs were at the market,” said Jeremy Kamil, a virologist at Louisiana State University Health Sciences Centre Shreveport.

He added: “It raises more questions about what the Chinese government really knows.”

Scientists cautioned that it was not clear that the genetic material from the virus and from raccoon dogs had been deposited at the same time.

Depending on the stability of genetic material from the virus and the animals, said Michael Imperiale, a virologist at the University of Michigan, “they could have been deposited there at potentially widely different times.”

Still, Dr Arturo Casadevall, an immunologist at the Johns Hopkins Bloomberg School of Public Health who co-authored a recent study with Imperiale examining the origin of the coronavirus, said that linking animal and viral material nevertheless added to the evidence of a natural spillover event.

“I would say it strengthens the zoonotic idea,” he said, “that is, the idea that it came from an animal at the market.”

In the absence of the actual animal that first spread the virus to people, Casadevall said, assessing the origins of an outbreak would always involve weighing probabilities. In this case, animals sold at the market were removed before researchers began taking samples in early 2020, making it impossible to find a culprit.

Tim Stearns, dean of graduate and postgraduate studies at the Rockefeller University in New York, said the latest finding was “an interesting piece of the puzzle,” although he said it was “not in itself definitive and highlights the need for a more thorough investigation.”

For all the missing elements, some scientists said the new findings highlighted just how much information scientists had managed to assemble about the beginnings of the pandemic, including home addresses for early patients and sequence data from the market.

Theodora Hatziioannou, a virologist at the Rockefeller University, said it was critical that the raw data be released. But, she said, “I think the evidence is overwhelming at the moment toward a market origin.”

And the latest data, she said, “makes it even more unlikely that this started somewhere else.”

Felicia Goodrum, an immunobiologist at the University of Arizona, said that finding the virus in an actual animal would be the strongest evidence of a market origin. But finding virus and animal material in the same swab was close.

“To me,” she said, “this is the next best thing.”

This article originally appeared in The New York Times.









Goldman Faces Lawmakers’ Demands for US Probe of Role With SVB

Gregory Korte
Fri, March 17, 2023 


(Bloomberg) -- A group of US lawmakers from California are asking for a federal investigation into what role Goldman Sachs Group Inc. might have played in the collapse of Silicon Valley Bank.

A letter Friday from 20 Democratic House members — led by Representative Adam Schiff — asks the Justice Department, the Securities and Exchange Commission and the Federal Deposit Insurance Corp. to include the New York-based investment bank in their preliminary investigations.

The request follows disclosures that Goldman Sachs served both as an adviser to the failed bank in late February and as the buyer of a $21 billion securities portfolio.

“Goldman Sachs stands to be paid more than $100 million for its role in a bond purchase that ultimately failed to save SVB from collapse,” the lawmakers said, citing an unconfirmed New York Times report. “As Goldman Sachs is poised to profit from SVB’s failure, we strongly urge you to analyze whether Goldman Sachs operated at ‘arm’s length’ in their role as adviser for SVB.”

A representative for Goldman Sachs didn’t immediately respond to a request for comment. Silicon Valley Bank, in a disclosure Tuesday, said the sale was “at negotiated prices.”

--With assistance from Sridhar Natarajan.


Collapse of Silicon Valley Bank Has Chinese Startups Worried
March 17, 2023 
John Xie
Silicon Valley Bank was the 16th-largest American bank before it failed this month.

WASHINGTON —

The collapse of Silicon Valley Bank has caused panic not just in the U.S. tech industry but also in China, where the bank has been a key player for years among Chinese startups.

In recent days, many startups in China have issued statements to reassure their investors that their deposits with SVB will not impact their operations.

Before the bank failed and was taken over by U.S. regulators this month, Silicon Valley Bank was the 16th-largest American bank. In foreign markets, SVB’s reputation for financing about half of all U.S. venture-backed technology and health care companies made it a popular choice for companies, including those based in China and backed by U.S. venture capitalists.

BeiGene, one of China's largest biotech companies that specializes in the development of cancer drugs, said that the collapse of SVB would have “no major impact” on its operations, and that its uninsured cash deposits in Silicon Valley Bank totaled only $175 million, or about 3.9% of its cash and other investments.

Zai Lab, a biopharmaceutical company headquartered in Shanghai, issued a statement saying that SVB’s collapse would have no impact on its operations, including the ability to pay wages and make payments to third parties.

Other startups, including Andon Health, Sirnaomics, Everest Medicines and Jacobio Pharma, have issued similar statements.

After SVB failed, the Biden administration stepped in and ensured that all customers would be able to get their deposits back, even those who had more than $250,000 in their accounts. That’s the maximum amount that the Federal Deposit Insurance Corporation typically covers when a bank fails, but more than 90% of Silicon Valley Bank accounts were above that amount.

With their SVB deposits frozen, many companies could have been at risk of failing themselves, so the Biden administration said it would step in to guarantee they would get their funds back.

FDIC reimbursements for Chinese customers?


On Chinese social media, there has been concern that the reimbursements may apply only to customers in America.

"Is it true that only depositors who are U.S. citizens can get their money back? What about us?" asked one post on Weibo, the Chinese version of Twitter.

William Hanlon, a partner at Seyfarth Shaw LLP, told VOA Mandarin in an email that the FDIC as receiver “will not categorize account holders by nationality” and “will treat all depositors equally based on their status as depositors.”

David M. Bizar, another partner at Seyfarth Shaw, said the FDIC is continuing to operate SVB as a full-service bridge bank while it searches for buyers of the bank's assets.

“It can be expected that the United States will continue to maintain these deposit accounts and keep them from losing their value so long as it maintains them in its receivership, and that the FDIC as receiver will not sell these deposit accounts to purchasers who would be permitted under the sale agreements to reduce their values after the transfers,” he told VOA.

So far, several Chinese companies have publicly said they were able to withdraw all their deposits at SVB.

SVB’s role in China


The now-failed SVB carved out a unique role in the Chinese banking scene. It served roughly 2,200 clients and advised government regulators who were eager to build the country’s tech sector. The Santa Clara, California-based bank supported startup companies that not all banks, especially the big commercial ones in China, would accept because of higher risks.

In 2010, then-CEO Ken Wilcox brought the entire board of directors to China to showcase the importance he attached to the China market, according to Chinese media reports. In a 2019 interview, when he was SVB’s chief credit officer, he said SVB was “a model bank for China.”

SVB approached China in two different ways. One involved wholly owned operations in major tech centers, including Beijing, Shenzhen and Shanghai, where it advised startups on how to manage overseas funding. The other involved a 50-50 joint-venture with Shanghai Pudong Development Bank, also known as SPD Silicon Valley bank, that operates under a similar model as SVB.

Following the collapse of SVB, the Chinese policymakers signaled stricter oversight to improve financial market security.

The South China Morning Post quoted Liu Xiaochun, deputy director of the Shanghai Finance Institute, as saying it was inappropriate to set up a similar specialist bank in China.

He argued that to avoid potential losses in supporting tech and health startups, large commercial banks should establish branches to finance innovation, while managing risk exposure at headquarters.


SVB failure offers lesson for China - state media

 -The collapse of Silicon Valley Bank (SVB) will not impact China's financial system but offers an important lesson for the country's banking industry, the official Securities Times said in an editorial on Wednesday.

An SVB-style bank failure is unlikely to happen in China but the incident would have "important implications for the development of China's small- and medium-sized lenders, and the stability of China's financial system," the editorial said.

SVB's shutdown on Friday has roiled global markets, forced U.S. President Joe Biden to rush out assurances that the financial system is safe and prompted emergency U.S. measures giving banks access to more funding.

In China, shares of smaller lenders including Bank of Lanzhou 001227.SZ, Xi An Bank 600928.SS and Xiamen Bank 601187.SS have far underperformed big banks over the past week, amid concerns over their ability to manage risks.

China's smaller banks, more vulnerable to interest rate risks, could suffer from shrinking interest spreads and investment losses during a rate hike cycle, GF Securities said in a report this week.

The Securities Times said that while the SVB incident reflects loosened regulation of such banks in the U.S., a slew of financial regulatory reforms in China over the past years have cleaned up the industry, curbed shadow banking and reduced financial risks.

In addition, China has been closing regulatory loopholes, the editorial said. In the latest move, China said last week it would set up a new national financial regulatory body consolidating oversight of the industry.

"Although the SVB incident won't have material impact on China's finiancial markets, China's financial industry still needs to earnestly learn from this lesson, and always prioritise risk prevention and control," the newspaper said.

SVB's SIVB.O China joint venture has also sought to ease fears among clients and investors, saying on Saturday it has a sound corporate structure and an independently operated balance sheet.


400k gallons of radioactive water leaked from Minnesota nuclear plant


At least 400,000 gallons of radioactive water leaked from a Minnesota nuclear power plant in November — but officials only publicly revealed the spill on Thursday.

Minnesota regulators shared the disconcerting development on Thursday and said they have been monitoring the cleanup from Xcel Energy’s Monticello nuclear plant.

While the energy company reported the leak of water containing tritium to state and federal authorities and the Nuclear Regulatory Commission last fall, state officials said they waited to tell the public until they had more information.

The four-month delay in announcing the leak to the public sparked an alarm over public safety and transparency. However, industry experts on Friday said there was never a public health threat as the radioactive water never reached a threshold that would have required public notification.

Xcel Energy’s Monticello nuclear plant.
The delay in notifying the public about the November leak at Xcel Energy’s Monticello nuclear plant raised questions about public safety and transparency.
KARE

“This is something that we struggle with because there is such concern with anything that is nuclear,” said Victoria Mitlyng, a spokesperson with the Nuclear Regulatory Commission. “The concern is very, very understandable. That is why I want to make extra clear the fact that the public in Minnesota, the people, the community near the plant, was not and is not in danger.”

Minnesota Pollution Control Agency spokesman Michael Rafferty said Thursday that officials knew that one of the plant’s monitoring wells contained tritium in November but “Xcel had not yet identified the source of the leak and its location.

 “Now that we have all the information about where the leak occurred, how much was released into groundwater and that contaminated groundwater had moved beyond the original location, we are sharing this information,” Rafferty said.

Xcel said the leak came from a pipe between two buildings.

Tritium is a radioactive isotope of hydrogen that occurs naturally in the environment and is a common by-product of nuclear plant operations. It emits a weak form of beta radiation that does not travel very far and cannot penetrate human skin, according to the Nuclear Regulatory Commission.

The chemical only poses a health risk to people who consumed a large amount of tritium, according to Edwin Lyman, director of nuclear power safety with the Union of Concerned Scientists. The risk is contained if the plume stays on the company’s site, which Xcel Energy and Minnesota officials said is the case.

Lyman said that if officials are certain that it did not leave the confines of the powerplant, people should not be concerned about their health or safety.

Cooling towers release heat generated by boiling water reactors at Xcel Energy's Nuclear Generating Plant on Oct. 2, 2019, in Monticello, Minn. Minnesota
Cooling towers release heat generated by boiling water reactors at Xcel Energy’s Nuclear Generating Plant on Oct. 2, 2019, in Monticello, Minnesota.
AP

“Xcel Energy took swift action to contain the leak to the plant site, which poses no health and safety risk to the local community or the environment,” the Minneapolis-based utility said in a statement.

Mitlyng said nuclear plants are not required to report all tritium leaks to the Nuclear Regulatory Commission, however Xcel had agreed to report certain leaks to the state, who, in turn, shares it with the commission.

On November 23, the commission posted a notification about the leak on its website, which it classified as a nonemergency and said was under investigation. No other notification was ever given to the public until Thursday.

There is no way for the tritium to get into the drinking water, Mitlyng said. The powerplanthas groundwater monitoring wells and plant employees regularly track the progress of contaminants by looking at which wells detect higher amounts.

Xcel said it has recovered about 25% of the spilled tritium so far, as Nuclear Regulatory Commission inspectors are on site too, monitoring the response.

The company said it plans to install a permanent solution this spring.

With Post wires

Millions of dead fish wash up near Australian town

 
Dead fish in the Baaka-Darling River

Millions of fish have died in a New South Wales river. Photo: Screenshot / ABC News

Residents in a regional Australian town have woken to find millions of dead fish in their river.

The large-scale fish deaths were first reported on Friday morning in the New South Wales' (NSW) town of Menindee.

The state's river authority said it was a result of an ongoing heatwave affecting the Darling-Baaka river.

Locals say it is the largest fish death event to hit the town, that experienced another significant mass death of fish just three years ago.

In a Facebook post, the NSW Department of Primary Industries (DPI) said the heatwave put "further stress on a system that has experienced extreme conditions from wide-scale flooding".

Heatwaves have become more frequent, more intense, and last longer because of human-induced climate change. The world has already warmed by about 1.1C since the industrial era began and temperatures will keep rising unless governments around the world make steep cuts to emissions.

Speaking to the BBC, Menindee resident Graeme McCrabb described the deaths as "surreal".

"It'll probably be a bit more confronting today," he said, as he warned that locals were anticipating that even more fish would die as the already decomposing fish sucked more oxygen from the water.

Around 500 people live in the town in far-west New South Wales. The Darling-Baaka river is a part of the Murray Darling Basin, Australia's largest river system.

The NSW DPI also said that the fish deaths were "distressing to the local community", a sentiment echoed by McCrabb.

"You can just imagine leaving a fish in your kitchen to rot with all the doors shut and no air conditioner, and we've got millions of them."

The temperature in Menindee was expected to reach 41C on Saturday.

He added that locals in the regional town rely on the Darling-Baaka for water supplies, "we use the river water for washing and showering in so people won't be able to use that water for those basic needs again," he said.

"Over time those people won't be able to access that water for domestic use which is just shameful".

This week's fish deaths throws a light on the troubles facing the Murray Darling Basin. Drought and increased human use has impacted the health of the Murray Darling ecosystem.

The Murray Darling Basin authority said agriculture, industries and communities have used water from the river system which has resulted in less water flowing through the river.

It also said the Basin is prone to extreme weather events and has a highly variable climate that makes it vulnerable to both fires and droughts.

In 2012, a plan worth A$13 billion was implemented to try and stop the river from drying up and returning it to a healthier level.

The NSW DPI said it will work with federal agencies to respond to the latest incident, and to find the underlying causes of the deaths.

BBC

Rolls-Royce to develop nuclear reactor to power UK base on the Moon

By Jacqueline Howard in London with wires
Concept design nuclear power on moon
Rolls-Royce released this concept image of a "space flower Moon micro reactor".(Supplied: Rolls-Royce)

The UK's Space Agency (UKSA) has commissioned Rolls-Royce to develop nuclear reactors that could power a base on the Moon.

Rolls-Royce was awarded £2.9 million ($5.26 million) to fund research into developing nuclear power that would operate in the desolate, zero-gravity environment.

The company's research centres around the concept of a micro-reactor, a portable power source that could operate in any environment.

The lunar modular reactor would power space missions, as well as support humans living and working on the Moon.

"This innovative research by Rolls-Royce could lay the groundwork for powering continuous human presence on the Moon, while enhancing the wider UK space sector, creating jobs and generating further investment," said UKSA chief executive Dr Paul Bate.

UK Science Minister George Freeman said, "Space exploration is the ultimate laboratory for so many of the transformational technologies we need on Earth: from materials to robotics, nutrition, clean-tech and much more. 

"As we prepare to see humans return to the Moon for the first time in more than 50 years, we are backing exciting research like this lunar modular reactor with Rolls-Royce to pioneer new power sources for a lunar base."

Rolls Royce said it plans to have a reactor ready to send to the Moon before 2030.

An astronaut in a white space suit looks across a dusty, grey plain where white pods link by tunnels
It's hoped the nuclear reactors could power a base on the Moon that would support the life of scientists conducting research in space.(Supplied: Rolls-Royce)

The company, best known to the average person for high-end cars, also operates in air and sea technologies.

Rolls-Royce will be fitting the newly announced Australian AUKUS submarines with nuclear propulsion systems.

Earlier this week, the UK government moved to reclass nuclear power as an 'environmentally sustainable' power source.

Britain has a number of ageing nuclear power stations, with all but one set to be decommissioned by 2028.

The change in classification would make it easier to green-light new developments to modernise the UK's power base.

A week of new space technologies

On Tuesday, the UK government awarded funding to Open Universities researchers to develop construction material out of resources on the Moon.

The concept being pursued by scientists involves melting down the soils that naturally make up the Moon's surface and 3D printing the substance into a concrete-like substance that can be built with.

NASA on Wednesday unveiled the first prototype for a newly designed next-generation spacesuit.

a dark grey space suit has pops of orange and blue on the shoulders and chest.
The grey is an outer layer — the true suit will be white, but the design is a closely guarded secret.(Supplied: Axiom)

Named the "Axiom Extravehicular Mobility Unit," or AxEMU for short, the new suits are more streamlined and flexible than the old Apollo get-ups, with greater range of motion and variability in size and fit.

They are designed to fit a broad range of potential wearers, accommodating at least 90 per cent of the US male and female population, NASA said. They also will incorporate advances in life-support systems, pressure garments and avionics.

The precise look of the suits, however, remained a closely guarded trade secret. Those on display came with an outer layer that was charcoal grey with dashes of orange and blue and Axiom's logo on the chest — intended to obscure Axiom's proprietary outer fabric design.

But the company said the suits to be worn on the lunar south pole by astronauts will be white because that is the best colour to reflect the harsh sunlight on the moon's surface and protect the wearer from extreme heat.

ABC/ Reuters