INCOME INEQUALITY KILLS
Excess deaths disproportionally occurred among Black, American Indian/Alaskan Native, and Latino males and females during the 2020 COVID-19 pandemic
Embargoed News from Annals of Internal Medicine
Peer-Reviewed Publication1. Excess deaths disproportionally occurred among Black, American Indian/Alaskan Native, and Latino males and females during the 2020 COVID-19 pandemic
Abstract: https://www.acpjournals.org/doi/10.7326/M21-2134
URL goes live when the embargo lifts
A large study of surveillance data found that excess deaths during the 2020 COVID-19 pandemic disproportionately occurred among Black, American Indian (AI)/Alaskan Native (AN), and Latino males and females in the U.S., compared to White and Asian males and females. According to the authors, these overwhelming disparities highlight the urgent need to address long-standing structural inequities affecting health and longevity. The findings are published in Annals of Internal Medicine.
Researchers from the National Cancer Institute, the National Institute for Minority Health and Health Disparities, and the Pacific Institute for Research and Evaluation, used data from the CDC National Center for Health Statistics to estimate deaths by month, year, sex, age group, race/ethnicity, and cause from March 1, 2020 (the first full month of the COVID-19 pandemic in the U.S.) to December 31, 2020. They found that compared with the number expected, based on 2019 data, 477,200 excess deaths occurred during the study period: 74% from COVID-19. The remaining fraction were attributed to causes including diabetes, heart disease, cerebrovascular disease, and Alzheimer disease. Black, AI/AN, and Latino males and females had more than double the number of excess deaths than White and Asian males and females, after standardizing by population size.
According to the authors, differences in COVID-19 risk, hospitalization, and death by race/ethnicity can be attributed to structural and social determinants of health with established and deep roots in structural racism. Studies have shown that Black and Latino persons are more likely to have occupational exposure to COVID-19, live in multigenerational households and/or more densely populated neighborhoods, and have less access to health care and private transportation, compared to White persons. Prior to a successful mass-vaccination program, AI/AN reservation–based communities were at further risk for infection due to a lack of infrastructure and chronically underfunded health care facilities.
The authors suggest that equitable vaccine distribution is needed to prevent further exacerbation of racial/ethnic disparities in COVID-19 risk and mortality. Inequities need to be addressed with urgency and cultural competence, as has been done by tribal communities.
JOURNAL
Annals of Internal Medicine
SUBJECT OF RESEARCH
People
ARTICLE TITLE
Racial and Ethnic Disparities in Excess Deaths During the COVID-19 Pandemic, March to December 2020
ARTICLE PUBLICATION DATE
5-Oct-2021
NCI study highlights pandemic’s disproportionate impact on Black, American Indian/Alaska Native, and Latino adults
The global COVID-19 pandemic has taken a toll on Black, American Indian/Alaska Native, and Latino individuals in the United States, causing more deaths by population size, both directly and indirectly, in these groups compared with white or Asian individuals. The findings, from a large surveillance study led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), appeared October 5, 2021, in Annals of Internal Medicine.
“Focusing on COVID-19 deaths alone without examining total excess deaths—that is, deaths due to non-COVID-19 causes as well as to COVID-19—may underestimate the true impact of the pandemic,” said Meredith S. Shiels, Ph.D., M.H.S., senior investigator in the Infections and Immunoepidemiology Branch in NCI’s Division of Cancer Epidemiology and Genetics, who led the study. “These data highlight the profound impact of long-standing inequities.”
Scientists at NCI have a long history of tracking mortality trends in the United States, mainly focusing on cancer death rates. More recently, these investigators have been applying their expertise in analyzing national surveillance data to better understand the impact of the COVID-19 pandemic on excess deaths by racial and ethnic group.
In this new study, scientists from NCI, NIH’s National Institute on Minority Health and Health Disparities (NIMHD), and the Pacific Institute for Research and Evaluation used provisional death certificate data from the Centers for Disease Control and Prevention, along with population estimates from the U.S. Census Bureau, to compare excess deaths by race/ethnicity, sex, age group, and cause of death during March to December 2020 with data for the same months in 2019. Excess deaths are the number of deaths in a specific period of time over what would have been expected to occur based on deaths in the same months in previous years, after adjustment for population changes.
Dr. Shiels noted that because the study period did not include a full year of data, the investigators could not present the number of excess deaths as a rate. Instead, they calculated the number of excess deaths in each racial/ethnic group according to each group’s population size (i.e., deaths per 100,000 people).
Roughly 2.9 million people died in the United States between March 1, 2020, and December 31, 2020. Compared with the same period in 2019, there were 477,200 excess deaths, with 74% of them due to COVID-19. The scientists found that, after adjusting for age, the number of excess deaths by population size among Black, American Indian/Alaska Native, and Latino men and women were more than double those in white and Asian men and women.
Looking more closely at the excess deaths where COVID-19 was not listed as the cause, the scientists found that excess deaths by population were three to four times higher among Black and American Indian/Alaska Native men and women compared with white men and women. And Latino men and women had nearly two times the number of excess non-COVID-19 deaths by population, compared with white men and women.
These data do not explain the reasons for the excess non-COVID mortality. “It is possible that fear of seeking out health care during the pandemic or misattribution of causes of death from COVID-19 are responsible for a majority of the excess non-COVID-19 deaths,” said Dr. Shiels.
Excess deaths during the pandemic have resulted in growing disparities in overall U.S. mortality, with the disparities in age-standardized all-cause deaths increasing between 2019 and 2020 for Black and American Indian/Alaska Native men and women compared with white men and women. For example, in 2019, total mortality by population among Black men was 26% higher than in white men, but in 2020 it was 45% higher. Similarly, in 2019, total mortality by population among Black women was 15% higher than in white women, but in 2020 it was 32% higher.
“Our efforts at NIH to help mitigate these COVID disparities have been heavily focused on promoting testing and vaccine uptake through community-engaged research. However, vaccine hesitancy poses a real threat, so we are addressing the misinformation and distrust through collaborative partnerships with trusted community stakeholders,” said study coauthor Eliseo J. Pérez-Stable, M.D., director of NIMHD.
The study was funded by the Intramural Research Programs of NCI and NIMHD.
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About the National Cancer Institute (NCI): NCI leads the National Cancer Program and NIH’s efforts to dramatically reduce the prevalence of cancer and improve the lives of cancer patients and their families, through research into prevention and cancer biology, the development of new interventions, and the training and mentoring of new researchers. For more information about cancer, please visit the NCI website at cancer.gov or call NCI’s contact center, the Cancer Information Service, at 1-800-4-CANCER (1-800-422-6237).
About the National Institute on Minority Health and Health Disparities (NIMHD): NIMHD leads scientific research to improve minority health and eliminate health disparities by conducting and supporting research; planning, reviewing, coordinating, and evaluating all minority health and health disparities research at NIH; promoting and supporting the training of a diverse research workforce; translating and disseminating research information; and fostering collaborations and partnerships. For more information about NIMHD, visit https://www.nimhd.nih.gov.
About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit nih.gov.
JOURNAL
Annals of Internal Medicine
DOI
METHOD OF RESEARCH
Observational study
SUBJECT OF RESEARCH
People
ARTICLE TITLE
Racial and Ethnic Disparities in Excess Deaths During the Covid-19 Pandemic, March to December 2020
ARTICLE PUBLICATION DATE
4-Oct-2021
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