Thursday, December 22, 2022

 Does diabetes during pregnancy increase the risk of neurodevelopmental conditions in children?

Peer-Reviewed Publication

WILEY

New research published in Developmental Medicine & Child Neurology has revealed a link between maternal diabetes during pregnancy and a range of neurodevelopmental conditions in children—including autism, attention-deficit/hyperactivity disorder (ADHD), developmental delay, intellectual disability, cerebral palsy, and epilepsy.

The retrospective study included 877,233 children born between 2004 and 2008 in Taiwan whose mothers had type 1, type 2, or gestational diabetes during pregnancy. The effect of type 1 diabetes on neurodevelopmental disorders was the largest, followed by type 2 diabetes, and then gestational diabetes.

Type 1 diabetes was associated with an increased risk of developmental delay, intellectual disability, and epilepsy in children. Type 2 diabetes was associated with an increased risk of autism spectrum disorder, ADHD, developmental delay, intellectual disability, cerebral palsy, and epilepsy. Gestational diabetes was associated with an increased risk of autism spectrum disorder, ADHD, and developmental delay.

“Mechanistic studies are needed to explore how maternal conditions, such as diabetes, may shape brain development in the womb,” said corresponding author Pao-Lin Kuo, MD, of National Cheng Kung University Hospital. 

URL upon publication: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.15488

 

Additional Information

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About the Journal

Developmental Medicine & Child Neurology (DMCN) is a multidisciplinary journal that has defined the fields of paediatric neurology and childhood-onset neurodisability for over 60 years. DMCN disseminates the latest clinical research results globally to enhance the care and improve the lives of disabled children and their families.

About Wiley

Wiley is one of the world’s largest publishers and a global leader in scientific research and career-connected education. Founded in 1807, Wiley enables discovery, powers education, and shapes workforces. Through its industry-leading content, digital platforms, and knowledge networks, the company delivers on its timeless mission to unlock human potential. Visit us at Wiley.com. Follow us on FacebookTwitterLinkedIn and Instagram.

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