The hidden power of Japanese food ― inhibiting the development of liver fibrosis

Intake of soy products, seafood, and seaweed is important

OSAKA METROPOLITAN UNIVERSITY

 

IMAGE: RESEARCHERS ANALYZED THE RELATIONSHIP BETWEEN MEALS RATED BY THE 12-COMPONENT MODIFIED JAPANESE DIET INDEX (MJDI12), MUSCLE MASS, AND LIVER FIBROSIS PROGRESSION IN 136 PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE (NAFLD) ATTENDING THE OSAKA METROPOLITAN UNIVERSITY HOSPITAL. view more 

CREDIT: OSAKA METROPOLITAN UNIVERSITY

Japanese food is popular worldwide and has been registered as a UNESCO Intangible Cultural Heritage. There is a scoring system named “the 12-component modified Japanese Diet Index (mJDI12),” which focuses on the intake of the Japanese diet pattern. It includes 12 foods and food groups: rice, miso soup, pickles, soy products, green and yellow vegetables, fruits, seafood, mushrooms, seaweed, green tea, coffee, and beef and pork. Scores range from 0 to 12, with higher scores indicating a diet that conforms to the Japanese food pattern.

A research group led by Dr. Hideki Fujii M.D. and Associate Professor Yoshinari Matsumoto at the Osaka Metropolitan University analyzed the relationship between meals rated by mJDI12, muscle mass, and liver fibrosis progression in 136 patients with nonalcoholic fatty liver disease (NAFLD) attending the Osaka Metropolitan University Hospital.

The research group found the following: the group with a higher mJDI12 showed a lower degree of liver fibrosis progression. Moreover, among the Japanese diet patterns, a high intake of soy products, seafood, and seaweed showed a suppressive effect on liver fibrosis progression. In addition, the group with a higher intake of soy products had higher muscle mass, and the group with higher muscle mass had a lower degree of liver fibrosis progression.

 “This study indicates that the Japanese diet pattern may be effective as a dietary treatment for NAFLD patients. We hope that further intervention studies will lead to the establishment of an effective diet for those patients,” concluded Professor Matsumoto.

Their findings were published in Nutrients.

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About OMU 

Osaka Metropolitan University is a new public university established in April 2022, formed by merger between Osaka City University and Osaka Prefecture University. For more research news visit https://www.omu.ac.jp/en/ or follow @OsakaMetUniv_en and #OMUScience.

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JOURNAL

Nutrients

DOI

10.3390/nu15051175 

METHOD OF RESEARCH

Observational study

SUBJECT OF RESEARCH

People

ARTICLE TITLE

Severity of Liver Fibrosis Is Associated with the Japanese Diet Pattern and Skeletal Muscle Mass in Patients with Nonalcoholic Fatty Liver Disease