Friday, June 09, 2023

LHAASO Records entire process of a tera-electronvolt gamma-ray burst during death of a massive star


Peer-Reviewed Publication

CHINESE ACADEMY OF SCIENCES HEADQUARTERS

LHAASO detected GRB 221009A at a significance level of more than 250 standard deviations 

IMAGE: LHAASO DETECTED GRB 221009A AT A SIGNIFICANCE LEVEL OF MORE THAN 250 STANDARD DEVIATIONS view more 

CREDIT: IMAGE BY IHEP


New research findings on the gamma-ray burst (GRB) named GRB 221009A from the Large High Altitude Air Shower Observatory (LHAASO) were published online by the journal Science on June 8, 2023. The study, entitled "A tera-electronvolt afterglow from a narrow jet in an extremely bright GRB 221009A," was completed by the LHAASO international collaboration.

About two billion years ago, a massive star more than 20 times heavier than the Sun used up the fusion energy from its nuclear fuel, instantly collapsed, and triggered a massive explosion, thus unleashing a collimated burst of cosmic fireworks known as a gamma-ray burst (GRB) that lasted hundreds of seconds. The high-energy gamma-ray photons, generated from the collision between the fireball and interstellar matter, traveled through the vast universe and headed straight toward Earth. In the evening of October 9, 2022, at 13:20:50 UT, these photons reached the field of view of LHAASO, where over 60,000 gamma-ray photons were collected. After several months of analysis, scientists finally unveiled the details of this explosion event.

LHAASO precisely measures for the first time the entire light curve of high-energy photons from the afterglow of a GRB

The flux of photons collected by LHAASO indicates that they came from the radiation following the main burst. The main burst, namely the prompt emission, is the initial massive explosion characterized by intense low-energy gamma-ray radiation. The following burst, known as the afterglow, is produced when the ejected matter collides with the surrounding interstellar gas at speeds very close to the speed of light. "LHAASO accurately measured the complete process of the afterglow for the first time, comprising the entire phase of tera-electronvolt gamma-ray flux from rise to decay," said CAO Zhen, principal investigator of the LHAASO project, spokesperson for the LHAASO collaboration, and professor at the Institute of High Energy Physics (IHEP) of the Chinese Academy of Sciences.

Based on the observation of tens of thousands of GRBs, scientists have developed seemingly perfect theoretical models and have strong confidence in them. LHAASO observed the complete high-energy light curve that other experiments have yet to reach, providing a perfect data base for precise tests of these theoretical models. Given the rarity of this event, which probably occurs only once a millennium, it is expected that this observed result will remain one of the best for the next several decades or even centuries.

LHAASO measures for the first time the rapid enhancement process of high-energy photon flux from a GRB

"At the beginning of onset of the afterglow, LHAASO detected for the first time the extremely rapid enhancement of photon flux," said YAO Zhiguo, a professor at IHEP and one of the corresponding authors of the paper. Within a time interval of less than two seconds, the flux increased by a factor of more than one hundred, followed by a slow rise that conforms to the expected characteristics of an afterglow. The early rapid enhancement phenomenon exceeds the expectations of previous theoretical models. This leads to a question: What mechanisms are actually at play. The published results would spark in-depth discussions within the scientific community regarding the mechanisms involved in GRBs, including energy injection, photon absorption, and particle acceleration.

LHAASO unveils the mystery of the brightness of the brightest-of-all-time GRB

LHAASO observations have shown that high-energy radiation decreases more rapidly in brightness around 10 minutes after the start of the afterglow. "This can be explained by the fact that the ejected material after the explosion forms a jet-like structure, and the rapid decrease in brightness occurs when the radiation angle extends to the edge of the jet," said WANG Xiangyu, a professor at Nanjing University and one of the corresponding authors of the paper. Due to the extremely early occurrence of this brightness transition, the measured angle of the jet is inferred to be extremely small, only 0.8 degrees. This is the smallest known jet angle to date, indicating that what was observed is actually the brightest core of a typical internally bright and externally dark jet. "The observer happens to be directly facing the brightest core of the jet, and it naturally explains why this gamma-ray burst is the brightest in history and why such an event is so rare," said DAI Zigao, a professor at the University of Science and Technology of China of CAS and one of the corresponding authors of the paper.

LHAASO's data-intensive observations at high-energy will reveal more mysteries

Within the short duration of this event, the number of photons LHAASO recorded exceeded the cumulative number of photons observed from the "standard candle" Crab Nebula over the past few years. "If the selection criteria were slightly relaxed, the photon count could even reach 100,000!" said ZHA Min, a professor at IHEP and one of the corresponding authors of the paper. As a comparison, other instruments in the similar energy band had detected less than 1000 photons in other GRBs so far, and they are only able to detect photons tens of seconds after the burst." As of now, there are still many unknowns in this burst event, and LHAASO scientists are still analyzing the data, in order to reveal more secrets. Please stay tuned for the subsequent analysis results from LHAASO," said Prof. CAO, expressing optimistic expectations for further achievements from LHAASO.

Background information: GRB

GRBs are the most intense astronomical explosion phenomena in the universe since the Big Bang. They refer to the sudden increase in gamma-ray emission from a particular direction in the sky. GRBs can last as short as a fraction of a second or as long as several hours. Short-duration GRBs are produced by the merger of two nearby compact celestial objects such as black holes or neutron stars, while long-duration GRBs are caused by the collapse and explosion of massive stars (supernovae) when their fuel is exhausted.

On October 9, 2022, at 13:16:59.59 UT, the Fermi spacecraft first detected an exceptionally bright GRB, which was assigned the name GRB221009A according to international convention. Subsequently, dozens of space- and ground-based detectors observed this burst. This GRB is a long-duration event, with its brightness surpassing that of previous GRBs by several tens of times. The extremely high photon flux saturated the detectors of multiple international experiments. China's LHAASO, the High-Energy Burst Explorer (HEBS) satellite, and the Insight-HXMT satellite simultaneously detected this GRB, achieving wide-ranging observations spanning 11 orders of magnitude in energy. The preprint of the satellite observations was published on March 28, 2023. Subsequent joint data analysis based on both space- and ground-based observations has been extensively carried out, and more research findings will be published successively.

Background information: LHAASO

LHAASO, one of China's major national scientific and technological facilities, aims to conduct cosmic ray observation and research. It is located on Haizi Mountain, Daocheng County, Sichuan Province. It has an average altitude of 4,410 meters and covers approximately 1.36 square kilometers. LHAASO consists of three kinds of arrays: the Kilometer Square Array (KM2A), which is a ground-based particle detector array covering one square kilometer and composed of 5,216 electromagnetic particle detectors and 1,188 muon detectors; the Water Cherenkov Detector Array (WCDA), which covers 78,000 square meters and comprises of 3,120 detection cells; and the Wide Field-of-view Cherenkov Telescope Array (WFCTA), consisting of 18 telescopes. LHAASO enables wide-band and compound measurements of gamma rays and cosmic rays from high-energy celestial sources, facilitating research in astrophysics and related fields. 

The current results are primarily provided by the WCDA. The WCDA utilizes 360,000 tons of purified water as a medium and employs 6,240 photomultiplier tubes placed underwater. It measures the secondary products of gamma rays or cosmic rays produced in the atmosphere, by collecting Cherenkov light signals generated by these secondary particles in water. The energy range of gamma-ray observations spans two orders of magnitude, from around 100 GeV to more than 10 TeV. With its wide field of view and high duty cycle capability, the WCDA has prominent advantages in capturing transient celestial phenomena like GRBs.

The LHAASO project is jointly funded by China's National Development and Reform Commission and the Government of Sichuan Province. The construction phase lasted for four years, commencing in July 2017. Facility construction was completed, and instruments became fully operational in July 2021.

Currently, 32 domestic and international universities and research institutes have become member institutions of the international collaboration of LHAASO, which includes approximately 280 collaborating scientists.

Reviews from Peter Meszaros, professor at Pennsylvania State University

Thanks to LHAASO's very large observing area and advanced detector technology, this is the first time that the synchrotron-self-Compton component of the external shock early afterglow light curve has been detected at TeV energies. This, furthermore, shows a deceleration feature providing a measurement of the bulk Lorentz factor of about 440. It also shows a light curve break, interpreted as a jet opening angle of about 0.8 degrees, which reduces the total energy of the jet to about 10^51 ergs, consistent with other GRBs.

Reviews from GAO He, professor of Department of Astronomy, Beijing Normal University

GRBs are the most violent explosive phenomena in the universe, with energy emitted within a few seconds equivalent to the total energy radiated by the Sun over 10 billion years. After half a century of research, scientists have realized that GRBs originate from very extreme physical environments, such as high magnetic fields, strong gravity, and ultra-fast speeds. As such, GRBs have become extreme physics laboratories favored in the field of astrophysics and even fundamental physics. People expect to use GRBs to study the cosmic evolutionary history, the origin of heavy elements, and the validity of relativity, as well as other significant questions. However, a profound understanding of the physical origins of GRBs themselves is a prerequisite for addressing these issues.

Up to now, tens of thousands of GRBs have been detected by human, and almost every breakthrough in understanding GRBs has been driven by observations of exceptional events. On October 9, 2022, the brightest GRB ever recorded (later named GRB221009A) was detected, and scientists estimated that such a bright GRB passing through the Earth occurs once in thousands of years. Human was incredibly fortunate this time because GRB221009A happened to fall within the optimal field of view of LHAASO. Living up to expectations, LHAASO provided the complete light curve and energy spectrum of a GRB at TeV energies for the first time, significantly promoting our understanding of GRB radiation mechanisms and jet structures.

Comments from anonymous reviewers invited by the journal

1. LHAASO Collaboration presents a very important, breakthrough observation of the earliest GRB afterglow in the TeV energy range.

2. This is an extraordinary experimental result that deserves to be published rapidly and is perfectly suited to the journal - it is likely to become one of the best cited papers in the field. I congratulate the collaboration on this result - that provides a completely new perspective on GRBs from this "once in a lifetime" event.

3. LHAASO observations of GRB 221009A caught for the first time the rising phase of the afterglow radiation … I'd like to congratulate the LHAASO Collaboration for the outstanding result.

 

African-led PrEPVacc HIV prevention study completes its enrolment


Business Announcement

PREPVACC

First enrolled volunteer to the PrEPVacc clinical trial receiving an injection 

IMAGE: THE FIRST PREPVACC VOLUNTEER PARTICIPANT RECEIVES AN INJECTION AT THE LAUNCH OF THE LAUNCH OF THE PREPVACC TRIAL AT THE MASAKA SITE OF THE MRC/UVRI AND LSHTM UGANDA RESEARCH UNIT, ON TUESDAY 15 DECEMBER 2020. view more 

CREDIT: PREPVACC INVESTIGATORS



Investigators have announced the completion of participant enrolments into the PrEPVacc trial at all four sites in East and Southern Africa. Led by African researchers, PrEPVacc is the first HIV vaccine efficacy trial to be conducted in East African countries and it is the only HIV vaccine efficacy trial being conducted in the world at present.

PrEPVacc is testing two different ways to prevent HIV, at the same time, which includes HIV vaccine regimens against a placebo (saline), and a new form of oral pre-exposure prophylaxis (PrEP) against the existing standard for PrEP.

Enrolment targets were achieved by all sites and enrolment concluded in March 2023. They began in December 2020 in Masaka, Uganda; in July 2021 in Mbeya, Tanzania; and in September 2021 in Dar es Salaam, Tanzania and in Durban, South Africa.

PrEPVacc’s Trial Director Dr Eugene Ruzagira, based at the MRC/UVRI & LSHTM Uganda Research Unit in Uganda said:

“Our profound thanks are due to all of the PrEPVacc study participants whose commitment is helping to move the field of HIV prevention forward both for their country and for the world. We are truly grateful to each of them, and to all the community members and supporters, friends and family who are behind them.”

“Congratulations to all the PrEPVacc teams on reaching their enrolment targets for the trial. They have worked hard and skilfully through very challenging periods during the COVID-19 pandemic in order to successfully and safely reach this point.”

“As we move into the post-recruitment phase there are still many participant study visits ahead during 2023 and into 2024. I urge everyone involved in PrEPVacc to remain committed and engaged through all of the visits, helping to ensure we produce the clearest results from this study that we are capable of. The study is scheduled to disseminate its findings by December 2024. We have already shared outcomes of our social science work with relevant stakeholders and we are committed to sharing news about all results that emerge from PrEPVacc with the study participants and their communities first.”

Participants are healthy adults aged 18-40 years who have voluntarily given full informed consent to take part in the PrEPVacc study, which has been approved by their site’s Research Ethics Committee. Study data reported by the end of May 2023 showed that 2,215 potential participants were screened for enrolment, and 1,512 participants were subsequently enrolled. Of the enrolled participants, 1,504 had started vaccinations, 623 were still receiving vaccines, and 671 had completed their fourth vaccination (of four scheduled).

The Masaka and Durban sites have enrolled both men and women while the Mbeya and Dar es Salaam sites have enrolled only women. Across all sites, 13% of participants are men, and 87% are women.

Participants in PrEPVacc are strongly committed to the study. By the end of their contribution over 17 months after the first vaccine injection, they will have made at least 15 study visits.

Participants received injections of either one regimen combining DNA with a protein-based vaccine, or a regimen combining DNA, MVA and a protein-based vaccine, or a placebo (saline). They were all also offered study PrEP as Descovy or Truvada through to two weeks after the third injection, and thereafter as locally sourced PrEP equivalent to Truvada. They received information on how best to incorporate PrEP in combination prevention against HIV.

Due to the challenges of successfully recruiting and enrolling into a clinical trial during the COVID-19 pandemic, and supply challenges with the MVA vaccine, PrEPVacc’s Investigators proposed a change to the randomisation of enrolled participants from 1:1:1 to 1:1 and discontinued enrolment to the MVA-combination vaccine arm in all sites by June 2022. Notwithstanding this change to enrolment, vaccinations and follow-ups have continued as planned in all arms. The trial minimum enrolment target was revised from 1,668 participants to 1,400, with encouragement to enrol beyond this in anticipation that some participants would miss their second or third vaccines and be excluded from the main vaccine analysis. The proposal was approved by PrEPVacc’s independent governance committees (https://www.prepvacc.org/organisation-and-governance).

PrEPVacc is not a licensure trial. Its findings will inform scientists as to whether developing either of the two different combination vaccine regimens for preventing HIV is worthwhile or not, even with the smaller sample size. If vaccine efficacy is shown, and the combination vaccine is safe, the result will need to be confirmed through a further trial or trials. PrEPVacc will also provide insights into PrEP adherence when needed for prevention and whether the new form of PrEP (Descovy) is as acceptable, safe and effective as the available oral standard PrEP (Truvada) among women.

The PrEPVacc trial was preceded by a preparedness study known as the “Registration Cohort” which gave research teams a better understanding of the community and HIV infection rates in the context of PrEP roll-out. During the Registration Cohort, sites developed a Community Advisory Board or Community Working Group whose members are local people who partner with the researchers and bring the concerns and interests of the community and study participants to the researchers. They also review study material to check that the language and messages used are simple and acceptable to their communities.

PrEPVacc is led by African researchers from Entebbe in Uganda, at the MRC/UVRI and LSHTM Uganda Research Unit. They are supported by 15 partner organisations, six from Africa, six from Europe and three from the US. The Sponsor of PrEPVacc is Imperial College London. See Notes to Editors (1) for a full list of partners.

The PrEPVacc study is funded by the European & Developing Countries Clinical Trials Partnership (EDCTP), as part of the EDCTP2 Programme supported by the European Union. See Notes to Editors (2) for a full list of funders.

During the recruitment and enrolment phase, an animated video version of the participant information sheet was used to explain the study to participants. It can now be found at https://youtu.be/zHYC6SKKobc

PrEPVacc website: www.prepvacc.org

-ends-

 

Notes to Editors

1. PrEPVacc partners

Behind PrEPVacc there are 80 senior scientists, clinicians, social scientists, community liaison specialists and professional support roles, from 15 partner organisations. They have extensive experience working with HIV and other infectious diseases, as well as clinical trials, and specifically in carrying out HIV vaccine and PrEP trials across Europe and sub-Saharan Africa.

  • Medical Research Council / Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Uganda
  • Muhimbili University of Health and Allied Sciences, Tanzania
  • National Institute for Medical Research - Mbeya Medical Research Centre, Tanzania
  • HIV and other Infectious Diseases Research Unit, South African MRC, South Africa
  • Imperial College London, UK
  • Medical Research Council Clinical Trials Unit at University College London, UK
  • Centre Hospitalier Universitaire vaudois, Switzerland
  • Karolinska Instituet, Sweden
  • Medical Center of the University of Munich (LMU), Germany
  • IAVI
  • Africa Health Research Institute
  • EuroVacc Foundation
  • Gilead Inc
  • Global Solutions for Infectious Diseases
  • East Virginia Medical School, CONRAD, USA

https://www.prepvacc.org/partners

2. PrEPVacc funders

PrEPVacc is a public-private partnership. The European & Developing Countries Clinical Trials Partnership (EDCTP) awarded a grant of €15M for the study and all of the institutional partners are providing co-funding through staff salaries. Gilead Inc and Inovio Pharmaceuticals are giving support to the project through materials and medicines. PrEPVacc is also supported by USAID and PEPFARUSMHRPSVRISAMRCUKRI, the Wellcome Trust and the Bill and Melinda Gates Foundation.

https://www.prepvacc.org/funders

Effective management of cardio-metabolic risk factors linked to the built environment

Scientists test a novel metric that links cardio-metabolic risk factors in men and women to the built environment

Peer-Reviewed Publication

JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Figure 1. Exploring the link between urban design and cardio-metabolic risk factors 

IMAGE: RESEARCHERS HAVE USED A NEW METRIC TO SHOW THAT CARDIO-METABOLIC RISK FACTORS FOR MEN AND WOMEN ARE LINKED TO THE BUILT ENVIRONMENT. view more 

CREDIT: SOURCE FREE PICTURE FROM "MONKEYSTYLE3000 AT FLICKR": HTTPS://WWW.FLICKR.COM/PHOTOS/132295270@N07/50065215408


Ishikawa, Japan -- Cardiovascular disease is still one of the two leading causes of non-communicable disease burden and death in North America. A growing body of evidence has linked the built environment to cardiovascular disease risk. A tried and tested approach to preventing cardiovascular disease is to target modifiable risk factors, such as physical activity. For instance, effective population-level interventions have immense potential to reduce cardiovascular disease burdens.

Drawing attention to the built environment's influence on cardio-metabolic health is gaining traction, given its well-known positive influence on physical activity. While many studies have investigated this association, generalizations cannot be applied between different countries due to differences in climate, healthcare systems, and culture. Furthermore, while the metrics employed to establish possible links between cardio-metabolic risk factors and the built environment have proven to be suitable for generating predictions, the information generated cannot be easily incorporated into making changes in urban design policy.

In a new study published in Preventive Medicine, a group of researchers led by Associate Professor Mohammad Javad Koohsari from the Japan Advanced Institute of Science and Technology, an adjunct researcher at the Waseda University as well, propose using a new metric, the space syntax walkability index, to address this limitation. Professor Koichiro Oka from Waseda University, Professor Tomoki Nakaya from Tohoku University, and Associate Professor Gavin R. McCormack from the University of Calgary in Canada were also involved in planning and executing the study.

Elaborating on the team's motivation, Dr. Koohsari says, "There is a growing awareness about the impact of urban design on cardio-metabolic health, but most of this work is based on studies in the US. We wanted to explore this relationship in the Canadian context, since findings from different geographical contexts may lack generalizability. While Canada is similar to Western developed countries in terms of its burden of cardio-metabolic risk factors, the interventions needed must account for local nuances."  

The research team analyzed data collected from 7,171 participants enrolled in the second wave of Alberta's Tomorrow Project (ATP). These participants lived in urban areas, had provided biological samples (serum, blood, and urine) for cardio-metabolic analyses, and had completed the follow-up health and lifestyle survey. Geographic information systems were then used to calculate two metrics, the traditional walkability index and the space syntax walkability index.

The research group's new urban design metric incorporates space syntax theory. By quantifying the degree of connectivity between streets, the space syntax walkability index represents street integration and describes how well connected a particular street is to others in the area. A highly integrated network requires fewer changes in direction to reach one's destination. "We found that the novel space syntax walkability metric was negatively correlated to systolic and diastolic blood pressure in men. This metric was also associated with less obesity among men and women. This shows that walkability in urban areas is linked to cardio-metabolic risk factors," stresses Dr. Koohsari when expanding on the study's conclusions.

So how can urban designers and planners improve our cities and design better interventions using this data?

Population-wide changes in cardio-metabolic risk factors can be implemented by creating health-supportive built environments, which enable people to easily make daily, healthy choices via long-term structural features. Dr. Koohsari explains, "This novel metric is likely to allow urban designers to identify poorly designed neighborhoods and target these environments for interventions specific to improving the cardio-metabolic risk factors. However, further studies are needed to better understand the relationships between neighborhood built environment and cardio-metabolic risk factors.”

Our altered lifestyle patterns and growing urbanization need not necessarily spell doom for our health and wellbeing. Through scientifically informed decision making and health-friendly planning, we can design built environments that support our fitness goals. This study is a right step in that direction.

 

###

Reference

Title of original paper:

Urban design and cardio-metabolic risk factors

Authors:

Mohammad Javad Koohsari*, Koichiro Oka, Tomoki Nakaya, Jennifer Vena, Tyler Williamson, Hude Quan, and Gavin R. McCormack

Journal:

Preventive Medicine

DOI:

10.1016/j.ypmed.2023.107552

 

 

About Japan Advanced Institute of Science and Technology, Japan

Founded in 1990 in Ishikawa prefecture, the Japan Advanced Institute of Science and Technology (JAIST) was the first independent national graduate school in Japan. Now, after 30 years of steady progress, JAIST has become one of Japans top-ranking universities. JAIST counts with multiple satellite campuses and strives to foster capable leaders with a state-of-the-art education system where diversity is key; about 40% of its alumni are international students. The university has a unique style of graduate education based on a carefully designed coursework-oriented curriculum to ensure that its students have a solid foundation on which to carry out cutting-edge research. JAIST also works closely both with local and overseas communities by promoting industry–academia collaborative research.  

 

About Associate Professor Mohammad Javad Koohsari from Japan Advanced Institute of Science and Technology, Japan

Dr Koohsari is an Associate Professor at the Creative Society Design Research Area, Japan Advanced Institute of Science and Technology in Japan. He also became an Adjunct Researcher with the Faculty of Sport Sciences at Waseda University, Japan. Dr Koohsari's research focuses on how built and virtual environment science can contribute to health, especially in the context of super-aged societies. Dr Koohsari has a publication record with over 110 refereed journal articles (such as at Nature Reviews Cardiology). In 2020 and 2021, he was recognised in the top 2% of most influential researchers worldwide across all scientific disciplines (Stanford University & Elsevier). He is also included in the 'Top Scientists' list in the field of 'Social Science & Humanities' for the year 2022 (Research.com). Dr Koohsari is on the editorial board member of several major journals in the field, such as Landscape & Urban Planning and Humanities & Social Sciences Communications.

 

Funding information: The Alberta's Tomorrow Project is supported by funding from Alberta Health, Alberta Cancer Foundation, Canadian Partnership Against Cancer, and Health Canada. Mohammad Javad Koohsari is supported by JSPS KAKENHI (Grant 23K09701). Gavin R. McCormack is supported by a Canadian Institutes of Health Research Foundations Scheme Grant (FDN-154331). Tomoki Nakaya received funding from the Japan Society for the Promotion of Science (JSPS) Grants-in-Aid for Scientific Research program (Grant 20H00040). Koichiro Oka received support from the JSPS Grants-in-Aid for Scientific Research program (Grant 20H04113).

Study highlights why people who are sexually harassed might not come forward immediately, or at all


New research has revealed there is a gap between how people imagine they’d act if sexually harassed and how those who experience it respond.

Peer-Reviewed Publication

UNIVERSITY OF EXETER




New research has revealed there is a gap between how people imagine they’d act if sexually harassed and how those who experience it respond.

The study by the University of Exeter, funded by the Economic and Social Research Council and published in Psychology of Women Quarterly, discovered that seeking justice by coming forward is just one of the needs people who experience sexual harassment consider after the event, with other needs, including those for safety, instead rated as more important.

The research may explain why people who are sexually harassed often don’t report their experience formally, with the 2017 Crime Survey England and Wales finding that five out of six people who are targeted by sexual offences do not report it to the police.

Researchers compared answers from a confidential online survey from people who have experienced sexual harassment to those who have not but were asked to imagine how they would react. People who have experienced sexual harassment reported a range of needs and engaged in a variety of actions to meet these needs. Needs for safety, personal control and social support were prioritised over formal actions, such as reporting to police. Those who had not encountered sexual harassment anticipated having stronger needs and taking more actions—especially formal ones.  

Senior author, Professor Manuela Barreto, from the University of Exeter said: “We found there is a widely held belief that quick and formal reporting is the correct response to sexual harassment. It’s what’s generally meant with the phrase ‘coming forward’. Yet most people who are sexually harassed do not report it formally and those who do, often report the offence a significant time after it happened. There’s a focus on procedural barriers with police and other authorities as to why this is, but less attention paid to the actual needs of the person who has experienced sexual harassment.

“Our research suggests there’s a gap between what people expect from those who have been sexually harassed and how those who experience it actually respond. It’s important to consider that the feelings and actions of someone who has experienced sexual harassment might be very different from those who have not. Instead of asking; ‘why people don’t come forward more often?’, we should perhaps ask ourselves; ‘what is the best action for the individual?’”

Across two studies researchers analysed answers from participants who have experienced sexual harassment about the actions they took, alongside those from participants who haven’t experienced sexual assault but were asked to imagine how they’d react if they did. In the first study 415 participants from mixed genders took part (259 experienced, 156 imaginers) and after finding no gender differences, the second study was conducted with women only (589 participants – 301 experienced, 288 imaginers), who are much more commonly sexually harassed.

Lead author, Professor Thomas Morton, worked at the University of Exeter on the research and is now at the University of Copenhagen. He said: “There is an assumption that those who experience sexual harassment are primarily guided by their desire for justice. But this research shows that peoples' needs are wider than what others might expect, and include needs for safety, personal control, and for life to just return to normal. Of all the needs that people expressed, the need for justice was not the highest priority. This might explain why people don’t take the kind of formal actions, like reporting to police, that others expect them to.

“There are often accusations – including high profile recent examples – that if people who experience sexual harassment don’t come forward at the time, it’s because it wasn’t that serious or perhaps even true. But if you have not experienced sexual harassment, it is hard to accurately anticipate what you might need, and therefore what you would do to satisfy those needs. Our research suggests that the assumptions people make are often wrong, or at least don’t reflect what the people who have experienced sexual harassment say they need.”

The paper is entitled “What Would a “Reasonable Person” Do? Exploring the Gap Between Experienced and Anticipated Responses to Sexual Harassment”, and is published in Psychology of Women Quarterly

ENDS

Eddies: Circular currents and their influence on the world's hottest ocean


Peer-Reviewed Publication

TOHOKU UNIVERSITY

Figure 1 

IMAGE: THE LEAD AUTHOR OF THIS PAPER, MOCHAMAD RIZA ISKANDAR, DEEPENED HIS RESEARCH WHILE AT TOHOKU UNIVERSITY BY DISCUSSING HIS FINDINGS WITH A NUMBER OF EXPERTS AT AN INTERNATIONAL WORKSHOP. view more 

CREDIT: TOHOKU UNIVERSITY'S INTERNATIONAL JOINT GRADUATE PROGRAM IN EARTH AND ENVIRONMENTAL SCIENCES



Water from the Pacific Ocean flows into the Indian Ocean via the Indonesia Archipelago Seas thanks to a vast network of currents dubbed the Indonesian Throughflow (ITF). The ITF acts as a heat and moisture conveyer belt, transporting warm and nutrient waters. Yet the ITF is neither a steady nor a straight path, but experiences fluctuations and turbulence as it passes through the various sea regions, straits, and passages.

Currents can sometimes formulate into circular motions, forming a whirlpool-like phenomena. These are known as eddies, and they are prominent in areas where there are strong gradients in temperature, salinity, or velocity. Their rotating motion can cause nutrients from the colder, deeper waters to rise to the surface.

To investigate the role eddies play in determining the path of the ITF, an international research group has harnessed a high-resolution ocean general circulation model that reproduces eddies. The group featured researchers from Tohoku University, JAMSTEC, Kyushu University, the University of Hawai`i at Mānoa, and the National Research and Innovation Agency of Indonesia.

Details of their research were reported in the Journal of Geophysical Research - Oceans on May 14, 2023.

The group's model enabled them to calculate the transport of simulated particles in a daily-averaged flow field with eddies and a monthly-averaged flow field with smoothed eddy currents, respectively, and estimate the flow rate transported by the simulated particles.

In the Sulawesi Sea, which is situated along the northeastern coast of Borneo and also borders the southern Filipino island of Mindanao, the Sulu archipelago, and Sulawesi Island's western coast, the group found that large flow fluctuations occur, and seawater circulates over a wider area for an extended period. Seawater also rises from the middle to near the surface, which may cause significant changes in the water when flowing through due to turbulent mixing.

On the eastern side of Sulawesi Island sits the Banda Sea, which surrounds the Maluku Islands and borders the islands of New Guinea and Timor. Here, the current fluctuation is slight, and the model predicted negligible influence from the eddies on the Indonesian Current.

"Our results indicate that the path and residence time of the ITF, along with the mixing process of seawater, must be appropriately reproduced by an ocean general circulation model to gain further insights into and better predict sea surface temperature fluctuations in each region of the Indonesian Archipelago," points out Toshio Suga, professor of physical oceanography at Tohoku University's Graduate School of Science and co-author of the paper.

Global warming's progression is expected to change the ITF. Such changes could have profound repercussions for water temperatures in the Indonesia Archipelago and the Indian Ocean, El Niño and the Indian Ocean Dipole, and the frequency and scale of marine heatwaves that affect marine ecosystems and local weather. Therefore, it is vital to predict accurately such phenomena.

Looking ahead, the group hopes to improve the accuracy of future predictions by clarifying the degree to which eddies impact the path and residence time of the ITF, something quantitatively linked to the determination of water temperature in these areas.

The figure shows the distribution of the difference between the daily and monthly average kinetic energies. This is an indicator of the magnitude of eddy variability. The eddy variability is large in the Sulawesi Sea and small in the Banda Sea.

Tracks of a number of particles originating in the Pacific Ocean that reach the Makassar Strait.

CREDIT

Iskander et al.

Importance of Wolbachia-mediated biocontrol to reduce dengue in Bangladesh and other dengue-endemic developing countries


Peer-Reviewed Publication

COMPUSCRIPT LTD



Mosquito-borne diseases, particularly dengue and chikungunya have become global threats, infecting millions of people worldwide, including developing countries of Southeast Asia and Latin America. Bangladesh, like many other developing countries, is experiencing frequent dengue outbreaks. This article, therefore, critically discusses the current status of dengue disease, vector control approaches, and the need for Wolbachia-mediated intervention in Bangladesh and other dengue-endemic developing countries.

Relevant literature was searched from major databases and search engines such as PubMed, BanglaJol, World Health Organization (WHO)/European Centre for Disease Prevention and Control (ECDC) and Google Scholar. Considering the selection criteria, search strategies finally involved 55 related literature for further investigation. Findings showed that current vector control strategies could not render protection for an extended period, and the disease burden of arboviruses is increasing. The impoverished outbreak preparedness, urbanization, climate change, and less efficacy of existing control methods have made people susceptible to vector-borne diseases. Hence, Wolbachia, a naturally occurring endosymbiont of many mosquito species that can potentially limit virus transmission through several host genetic alterations, would be a potential alternative for dengue prevention.

The authors also critically discuss the challenges and prospects of Wolbachia-based dengue control in developing countries. The evidence supporting the efficacy and safety of this intervention and its mechanism have also been elucidated. Empirical evidence suggests that this introgression method could be an eco-friendly and long-lasting dengue control method. This review helps policymakers and health experts devise a scheme of Wolbachia-based dengue control that can control mosquito-borne diseases, particularly dengue in Bangladesh and other developing countries.

 

Highlights

  • Approximately 3.9 billion people are prone to the dengue virus.
  • Current vector control strategies have been found less effective and cannot render protection for a long period.
  • Wolbachia-mediated biocontrol could be a promising alternative for dengue prevention.
  • Wolbachia grow naturally in 40%–60% of all insect species.
  • This dengue-control intervention is eco-friendly and confers long-term control.

 

Keywords: Wolbachia-based biocontrol, Mosquitoes-borne diseases, Dengue, Biological control, Developing countries

 

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CiteScore: 4.8

ISSN 2590-0536

 

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Abdullah Al Noman, Debashish Das, Zinnatun Nesa, Md. Tariquzzaman, Fariha Sharzana, Md. Rakibul Hasan, Baizid Khoorshid Riaz, Golam Sharower, Mohammad Meshbahur Rahman, Importance of Wolbachia-mediated biocontrol to reduce dengue in Bangladesh and other dengue-endemic developing countries, Biosafety and Health, Volume 5, Issue 2, 2023, Pages 69-77, ISSN 2590-0536, https://doi.org/10.1016/j.bsheal.2023.03.003