Wednesday, August 14, 2024

Mizzou scientists achieve more than 98% efficiency removing nanoplastics from water



The liquid-based solution uses a solvent to trap the plastic particles, leaving clean water behind.



Peer-Reviewed Publication

University of Missouri-Columbia

Gary Baker 

image: 

“Our strategy uses a small amount of designer solvent to absorb plastic particles from a large volume of water,” said Gary Baker, an associate professor in University of Missouri’s Department of Chemistry.

view more 

Credit: Sam O’Keefe/University of Missouri





COLUMBIA, Mo. — University of Missouri scientists are battling against an emerging enemy of human health: nanoplastics. Much smaller in size than the diameter of an average human hair, nanoplastics are invisible to the naked eye. 

Linked to cardiovascular and respiratory diseases in people, nanoplastics continue to build up, largely unnoticed, in the world’s bodies of water. The challenge remains to develop a cost-effective solution to get rid of nanoplastics while leaving clean water behind. 

That’s where Mizzou comes in. Recently, researchers at the university created a new liquid-based solution that eliminates more than 98% of these microscopic plastic particles from water. 

“Nanoplastics can disrupt aquatic ecosystems and enter the food chain, posing risks to both wildlife and humans,” said Piyuni Ishtaweera, a recent alumna who led the study while earning her doctorate in nano and materials chemistry at Mizzou. “In layman’s terms, we’re developing better ways to remove contaminants such as nanoplastics from water.” 

The innovative method — using water-repelling solvents made from natural ingredients — not only offers a practical solution to the pressing issue of nanoplastic pollution but also paves the way for further research and development in advanced water purification technologies. 

“Our strategy uses a small amount of designer solvent to absorb plastic particles from a large volume of water,” said Gary Baker, an associate professor in Mizzou’s Department of Chemistry and the study’s corresponding author. “Currently, the capacity of these solvents is not well understood. In future work, we aim to determine the maximum capacity of the solvent. Additionally, we will explore methods to recycle the solvents, enabling their reuse multiple times if necessary.” 

Initially, the solvent sits on the water’s surface the way oil floats on water. Once mixed with water and allowed to reseparate, the solvent floats back to the surface, carrying the nanoplastics within its molecular structure. 

In the lab, the researchers simply use a pipette to remove the nanoplastic-laden solvent, leaving behind clean, plastic-free water. Baker said future studies will work to scale up the entire process so that it can be applied to larger bodies of water like lakes and, eventually, oceans. 

Ishtaweera, who now works at the U.S. Food and Drug Administration in St. Louis, noted that the new method is effective in both fresh and saltwater. 

“These solvents are made from safe, non-toxic components, and their ability to repel water prevents additional contamination of water sources, making them a highly sustainable solution,” she said. “From a scientific perspective, creating effective removal methods fosters innovation in filtration technologies, provides insights into nanomaterial behavior and supports the development of informed environmental policies.” 

The Mizzou team tested five different sizes of polystyrene-based nanoplastics, a common type of plastic used in the making of Styrofoam cups. Their results outperformed previous studies that largely focused on just a single size of plastic particles. 

“Nanoplastics extraction from water by hydrophobic deep eutectic solvents” was published in ACS Applied Engineering Materials. Additional co-authors are Mizzou’s Collen Ray, Wyland Filley and Garrett Cobb.

Gary Baker, an associate professor in the University of Missouri’s Department of Chemistry, looks at a bottle of a new liquid-based solution that eliminates more than 98% of microscopic plastic particles from water.

Once mixed with water and allowed to reseparate, the solvent floats back to the surface, carrying the nanoplastics within its molecular structure.

Credit

Sam O’Keefe/University of Missouri

This illustration outlines the two-step extraction method.

Credit

Photo courtesy of Gary Baker.

 

Common equine painkiller disrupts assisted reproduction technique efficiency in mares, Texas A&M research finds




Texas A&M University




By Courtney Price, Texas A&M University School of Veterinary Medicine and Biomedical Sciences

Researchers at the Texas A&M School of Veterinary Medicine & Biomedical Sciences (VMBS) have discovered that phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID) commonly prescribed in horses, can affect the ability of a mare’s egg cells — called “oocytes” — to become viable embryos, which is a crucial step in assisted reproduction in horses.

This discovery, recently published in the journal Theriogenology, is significant because of the time and money that horse owners often invest in assisted reproduction. 

Just like humans, horses sometimes need help from science in order to reproduce. When they do, special steps are needed for a successful pregnancy because of the unique properties of equine sex cells.

“In horses, the process of in-vitro fertilization (IVF) is more complex than it is in humans,” said Dr. Luisa Ramirez-Agamez, a Ph.D. candidate in the VMBS’ Department of Large Animal Clinical Sciences (VLCS) studying equine reproduction. “First, a mare’s oocytes need approximately 30 hours to mature in the laboratory once they have been collected before they can be fertilized. Then, we have to inject the eggs with sperm to induce fertilization, a process known as Intracytoplasmic Sperm Injection (ICSI).

“We discovered that phenylbutazone, commonly known as bute, can affect both the ability of a mare’s eggs to mature correctly when cultured and whether the fertilized eggs will develop into a viable embryo,” she explained. “In either of those cases, the eggs affected by bute cannot be used in assisted reproduction.”

The Value Of Equine Assisted Reproduction

Assisted reproduction is an important resource for many horse owners, especially those who make a living from their herds. Many horse owners also care deeply about producing offspring from their favorite horses in order to carry on their legacies.

In some cases, mares who are chronically lame and unable to support a pregnancy themselves may become egg donors, with their eggs fertilized in a laboratory and carried to term by a surrogate.

“This is one of the specific situations impacted by our discovery,” Ramirez said. “Mares who are chronically lame are likely going to be on bute because it helps with pain management — especially in the musculoskeletal system — which, according to our results, will hinder their ability to participate in assisted reproduction programs.

“In a future study, we hope to determine an alternative to bute that supplies the same level of pain management but does not interfere with reproduction,” she said.

The good news is that bute’s effect on equine oocytes appears to wear off within a few weeks.

“We collected the eggs at three days post treatment, then 33 days, and then 77 days,” she said. “We found that eggs collected three days after administration of bute were not able to produce embryos, but those collected at 33 days were successful. We hope to find a more exact answer in terms of how bute affects egg cell quality in a future study.”

Implications For Human Medicine

Looking to the future, Ramirez is interested in collaborating with researchers in human medicine because of the possible implications of her discovery for IVF in women.

“NSAIDs are often given to women during IVF to slow down their ovulation cycle, which is the ovaries’ release of an egg each month,” she explained. “Under normal circumstances, most women only produce one egg cell each month, but IVF is expensive and time-consuming, so women are given hormones that cause them to produce more than one egg each cycle. This way, there is more than one egg to collect. NSAIDs help prevent women from ovulating early so they don’t lose those eggs.”

But after her recent discovery about NSAIDs and horse reproduction, Ramirez wonders if NSAIDs could also have unknown negative effects on IVF.

“NSAIDs are generally thought to have a positive impact on IVF in women, but our results suggest that these drugs are not as benign for reproduction in horses,” Ramirez said. “Some NSAIDs, like Banamine, actually cause anovulatory follicles in horses — follicles in the ovaries that don’t release egg cells during ovulation as they are supposed to.

“This is not the case in women, and so NSAIDs are thought to be safe. But now we know that bute can actually keep fertilized eggs from becoming embryos, and it’s possible that some NSAIDs could have a similar effect in women,” she said. “This is something I want to find out.”

 

NIFA grant supports innovative blackberry research in Arkansas



•Research on growing blackberries indoors funded to support long-term sustainability



University of Arkansas System Division of Agriculture

Ryan Dickson in greenhouse 

image: 

Ryan Dickson, an assistant professor of horticulture for the Arkansas Agricultural Experiment Station, has been developing research since 2018 on growing blackberries indoors and recently secured a nearly $750,000 grant to further that work over the next four years.

 

view more 

Credit: U of A System Division of Agriculture photo by Paden Johnson





(NEWSROOMS: This version replaces the story which was originally posted on July 30, 2024. This version SUBs lede to remove reference to ‘indoors.’ Story also has additional source-requested clarifications throughout)

FAYETTEVILLE, Ark. — Ryan Dickson, an assistant professor of horticulture for the Arkansas Agricultural Experiment Station, has been developing research since 2018 on growing blackberries in soilless substrates and recently secured a nearly $750,000 grant to further that work over the next four years.

The experiment station is the research arm of the University of Arkansas System Division of Agriculture. The grant comes from the U.S. Department of Agriculture’s National Institute of Food and Agriculture and is part of the Foundational Knowledge of Agricultural Production Systems program within the Agriculture and Food Research Initiative.

“Consumer demand is increasing for fresh-market blackberries, so this work promotes the ability of U.S. blackberry producers to meet domestic demands long-term,” said Dickson, whose research focus is on greenhouse and controlled environment agriculture.

According to the Packer’s Fresh Trends 2024 survey, 33.2 percent of consumers said they purchased fresh blackberries in the past year, compared with past survey results of 25 percent in 2023, 26 percent in 2022 and 28 percent in 2021. 

One of the issues blackberry growers are facing, Dickson said, is declining yield caused by soilborne pathogens which erodes profit margins. Breeding for disease resistance is an option, he noted, but is time-consuming and shouldn’t be relied on solely because it does not solve all the issues farmers are facing.

Dickson’s research aims to evaluate innovative soilless long-cane production techniques designed to increase yields, improve fruit quality and extend the growing season to enhance the profitability and sustainability of blackberry farming.

Making it an integrated research and extension project, Dickson will work with Amanda McWhirt, extension fruit and vegetable horticulture specialist and associate professor for the Division of Agriculture, to evaluate soilless long-cane production techniques. The Arkansas Cooperative Extension Service is the public outreach side of the Division of Agriculture.

Long-cane method

Dickson’s research calls for growing blackberries in soilless substrate containers using the long-cane system. The blackberries are first grown outdoors in containers and trained to form long canes for easier management and high-density production later on.

Dickson has been testing Arkansas-bred floricane varieties that typically need two seasons to produce fruit. The idea, he said, is to essentially trick plants into feeling like they have gone through a wintertime by keeping them in a walk-in cooler. After this artificial winter, the plants are transferred to a warm high tunnel or greenhouse, ready to produce fruit on demand, out of season.

Dickson said the main goals and potential benefits of long-cane blackberry production are increased yields, more consistent fruit quality and out-of-season production.

Moving the blackberry industry forward

The project has three main focus areas:

  • Cultivar selection and cultural practices — Researchers will evaluate how different blackberry cultivars and targeted cultural practices influence long-cane yield, fruit quality, and timing.
  • Economic analysis — The project will include breakeven and risk analyses for both long-cane and field-based blackberry systems, focusing on key profitability drivers.
  • Outreach — Rapid and long-term application of research results will be delivered to regional and national stakeholders.

Experiments will be conducted in high tunnels at the Milo J. Shult Agricultural Research and Extension Center in Fayetteville and the Fruit Research Station in Clarksville. The tunnels will be equipped with automated systems for irrigation and “fertigation,” in which fertilizer salts are dissolved in the applied irrigation water, and plants will be grown in coconut coir substrate. The research will involve collaboration with industry sponsors and the Division of Agriculture's fruit breeding program.

To learn more about Division of Agriculture research, visit the Arkansas Agricultural Experiment Station website: https://aaes.uada.edu. Follow on Twitter at @ArkAgResearch. To learn more about the Division of Agriculture, visit https://uada.edu/. Follow us on Twitter at @AgInArk. To learn about extension programs in Arkansas, contact your local Cooperative Extension Service agent or visit www.uaex.uada.edu.

About the Division of Agriculture

The University of Arkansas System Division of Agriculture’s mission is to strengthen agriculture, communities, and families by connecting trusted research to the adoption of best practices. Through the Agricultural Experiment Station and the Cooperative Extension Service, the Division of Agriculture conducts research and extension work within the nation’s historic land grant education system.

The Division of Agriculture is one of 20 entities within the University of Arkansas System. It has offices in all 75 counties in Arkansas and faculty on five system campuses.

The University of Arkansas System Division of Agriculture offers all its Extension and Research programs and services without regard to race, color, sex, gender identity, sexual orientation, national origin, religion, age, disability, marital or veteran status, genetic information, or any other legally protected status, and is an Affirmative Action/Equal Opportunity Employer.

 

Australians outlive their peers in high income Anglophone countries by 1-4 years



Most of difference accrues between ages of 45 and 84. Lower death rate from drugs/alcohol, screenable cancers, cardiovascular + respiratory diseases



BMJ Group





Australians outlive their peers in 5 high income English speaking countries, including the UK and the US, by between 1 to 4 years, finds an analysis of international longevity data, published in the open access journal BMJ Open.

Most of this advantage accrues between the ages of 45 and 84, with death rates from drug and alcohol misuse, screenable/treatable cancers, and cardiovascular and respiratory diseases all lower, the analysis shows.

While high income countries achieved good life expectancy gains during the 20th century, the trends have been much less favourable in the 21st century, even before the COVID-19 pandemic, note the researchers. 

Stalled declines in deaths from cardiovascular disease, along with a rising death toll from drug overdoses, mental illness, and neurological disease, are key contributory factors, they explain. And sizeable gaps in life expectancy between the richest and poorest, which are evident in most of these countries, have widened further in recent decades.

While English speaking high income countries have much in common, they also have notable differences, including in their healthcare and welfare systems, inequality, racial and ethnic composition, and history of immigration.

The researchers therefore wanted to know if there were any lifespan differences among Australia, Canada, Ireland, New Zealand, the UK, and the USA, which represent some of the wealthiest economies in the world.

They obtained national life tables from the Human Mortality Database (HMD) for men and women in these countries plus—for context only—Austria, Belgium, Denmark, Finland, France, Germany, Italy, Japan, the Netherlands, Norway, Portugal, Spain, Sweden and Switzerland between 1990 and 2019. 

Detailed information on deaths by sex, age, and cause of death were obtained from the World Health Organization Mortality Database for all 6 English speaking countries.

Analysis of the data showed that Australia has been the best performer in life expectancy at birth since the early 1990s, leading its peer countries by 1.26–3.95 years for women and by 0.97–4.88 years for men in 2018.

Specifically, Australia has a 4 to 5 year life expectancy advantage over the USA and a 1 to 2.5 year advantage over Canada, New Zealand, Ireland, and the UK.

For most of the period between 1990 and 2019, Canada had the second highest life expectancy. Most recently, Ireland and New Zealand have matched Canada. 

But in every year since 2001, the USA has been the worst performer. And in the most recent decade, the UK generally had the second lowest life expectancy. 

Similar trends are observed for life expectancy at age 65, with Australia generally performing the best and the USA the worst, with the USA’s poor life expectancy ranking at age 65 emerging more recently. 

The gaps in life expectancy at birth between the best and worst performers widened over time. In 1990, Canadian men and women had the highest life expectancies—74 and 80, respectively; American men and Irish women had the lowest—71 and 77, respectively. 

The corresponding gaps were 2.38 and 2.91 years. By 2019, these gaps had doubled to 4.75 years for men and increased by 30% for women to 3.80 years between Australia and the USA.

While women in English speaking countries never ranked among the top performers in female life expectancy between 1990 and 2019 in all 20 high income countries, men—with the exception of the USA— typically have ranked in the top half over the past decade. 

And out of all these countries, Australian men ranked in the top 4 in all but 1 year between 1990 and 2019. But American men have had the lowest life expectancy since 2005.

The 65–84 age group typically makes the single largest contribution to life expectancy gaps between Australia and the other 5 English speaking high income countries, ranging from 39% in the USA to 78% in Ireland among women, and from 30% in the USA to 100% in Ireland among men.

While Australians have lower rates of death across nearly all ages, most of their life expectancy advantage accrues between ages 45 and 84. 

Ischaemic heart disease, other circulatory diseases, cancers, respiratory diseases, mental illness and neurological disease—mostly Alzheimer’s disease and related dementias—are key contributors to life expectancy gaps in this age group.

But Australia also tends to have a lower death rate from external causes, including drugs and alcohol, screenable/treatable cancers, cardiovascular disease, and flu/pneumonia.

As to life expectancies within countries, Canada and the USA perform the worst, with 13 US states in the lowest category for men and women. On the other hand, all regions in the UK and Ireland have life expectancies above 81 for women and 76.5 for men. 

For both men and women, Australia has the lowest within country inequality, especially at ages above 40, followed by Canada. Among women, inequality tends to be highest in New Zealand, Ireland and the USA; among men, it is highest in New Zealand, the UK, and the USA.

The researchers acknowledge that they couldn’t account for differences within local neighbourhoods, and that there may be differences in cause of death coding, particularly at older ages where several conditions may co-exist.

But there are several possible explanations for Australia’s top ranking, they suggest, among which are the country’s high proportion of people born overseas—nearly 30% in 2018. 

A low prevalence of smoking might be another, while public health initiatives around gun ownership and mental health, and its highly rated healthcare system, might also explain Australia’s position at the top of the life expectancy league table.

“Australia performs well, but still has room for improvement, particularly in the area of reducing inequalities among its indigenous populations,” and in its rates of obesity, say the researchers.

But they conclude: “Overall, Australia offers a potential model for lower-performing Anglophone countries, such as the USA and UK, to follow to reduce both premature mortality and inequalities in life expectancy.”

Australia offers lessons for increasing American life expectancy


Penn State





UNIVERSITY PARK, Pa. — Despite being home to some of the world’s most dangerous animals, Australia has led the English-speaking world in life expectancy for the last three decades. As for other high-income Anglophone countries, the Irish saw the largest gains in life expectancy, while Americans have finished dead last since the early 1990s, according to a team of social scientists led by a Penn State researcher.  

The team published their findings today (August 13) in the journal BMJ Open

“One lesson we Americans can learn about life expectancy from looking at comparable countries is where the frontier of best performance lies,” said Jessica Ho, associate professor of sociology and demography at Penn State and senior author on the paper. “Yes, we’re doing badly, but this study shows what can we aim for. We know these gains in life expectancy are actually achievable because other large countries have already done it.” 

The researchers compared life expectancy in the United States, Canada, Ireland, the United Kingdom, Australia and New Zealand using data from the Human Mortality Database and the World Health Organization Mortality Database between 1990 and 2019. They analyzed the data by sex, age and 18 individual and comprehensive cause of death categories, including cancers, drug- and alcohol-related deaths, firearms and motor vehicle collisions. 

They also examined life expectancy within each country to identify geographical inequalities in life expectancy by region. 

The researchers found that Australians had the longest life expectancy at birth over the study period, with women living nearly 4 more years and men 5 more years than their American counterparts. The Irish showed the largest gains in life expectancy, with men’s lifespans increasing by approximately 8 years and women’s lifespans by more than 6.5 years. Americans had the shortest life expectancy at birth, with women living an average of almost 81.5 years and men an average of nearly 76.5 years in 2019. 

The United States also showed some of the largest geographical inequalities in life expectancy compared to the other countries, according to the researchers. Women and men in California and Hawaii had some of the highest life expectancies at birth, with women averaging 83 to 83.9 years and men averaging 77.5 to 78.4 years. States in the American Southeast saw some of the lowest life expectancies at birth of all subnational regions studied, with women averaging 72.6 to 79.9 years and men averaging 69.3 to 74.4 years. 

“One of the main drivers of why American longevity is so much shorter than in other high-income countries is our younger people die at higher rates from largely preventable causes of death, like drug overdose, car accidents and homicide,” said Ho, who is also an associate of Penn State’s Social Science Research Institute

In midlife — the 45 to 64 age range — some of these causes continue, like high death rates from drug- and alcohol-related mortality, Ho explained, adding that Americans also see higher rates of cardiovascular disease mortality.  

“Some of the latter could be related to sedentary lifestyle, high rates of obesity, unhealthy diet, stress and a history of smoking,” she said. “It’s likely that these patterns of unhealthy behaviors put Americans at a disadvantage in terms of their health and vitality.” 

Australia offers the U.S. a model for improving its life expectancy, Ho added. Like the U.S., Australia is large in terms of land area and has a comparable history of personal vehicle ownership. The two countries have some cultural similarities, including historically greater use of firearms. However, Australia implemented a number of policies in recent decades including gun law reforms that helped vault them to the top of the life expectancy rankings.   

“What the study shows is that a peer country like Australia far outperforms the U.S. and was able to get its young adult mortality under control,” Ho said. “It has really low levels of gun deaths and homicides, lower levels of drug and alcohol use and better performance on chronic diseases, the latter of which points to lifestyle factors, health behaviors and health care performance.”  

Ho said policies like investing in public transit infrastructure, adding more roundabouts and having fewer large cars on the road could decrease traffic deaths in the United States. More support for programs designed to reduce drug dependence and reducing barriers to treatment and prevention of drug overdose could help lower drug-related mortality, she said. And having a strong combination of public health effort, health care access and community interventions to encourage healthier lifestyles and the use of preventive medicine could reduce cardiovascular disease mortality, she added. 

“Australia is a model for how Americans can do better and achieve not only a higher life expectancy but also lower geographic inequality in life expectancy,” Ho said. 

Rachel Wilkie, a doctoral student at the University of Southern California, also contributed to this research. The National Institute on Aging of the National Institutes of Health supported this work. 

 

Childhood maltreatment is associated with greater cognitive difficulties than previously thought




King's College London




SMC Labels – Peer reviewed observational study on humans 

Childhood maltreatment is associated with greater cognitive difficulties than previously thought  

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London and City University of New York suggests that the cognitive difficulties associated with childhood maltreatment, and particularly neglect, have been grossly underestimated in previous studies.  

The research, published in Lancet Psychiatry, suggests that the overreliance on retrospective self-reports of maltreatment in research has resulted in a biased evidence base that overlooks the challenges faced by children and young people with documented exposure to maltreatment. 

Researchers in this study tested the relative associations of court-documented exposure to, and adult recall of, childhood maltreatment with cognitive abilities within the same individuals. 1179 participants were identified from an ongoing cohort in the USA. All participants underwent a variety of tests in order to assess their cognitive abilities in adult life.  

Researchers found that participants with official records of childhood maltreatment showed, on average, cognitive deficits across most tests undertaken compared to those without records. In contrast, the participants who retrospectively self-reported maltreatment did not demonstrate deficits when compared with those without reports.  

Researchers also noted that these findings were not consistent across the different types of maltreatment. Participants who had documented experiences of neglect demonstrated cognitive deficits, but those who had documented experiences of physical and sexual abuse did not.  

Andrea Danese, Professor of Child & Adolescent Psychiatry at King’s IoPPN and one of the study’s co-authors said, “While there are some important exceptions, most research in this area has relied on retrospective reports of childhood maltreatment from adult participants. Our study has shown that this reliance on retrospective reports has likely resulted in researchers and clinicians underestimating the extent to which individuals with documented cases of maltreatment, and particularly neglect, are experiencing cognitive deficits. 

“Our study highlights the importance of identifying young people who have experienced neglect so that the proper support can be put in place, for example, to mitigate the negative consequences in education and employment.” 

More research is needed to understand why individuals with documented histories of neglect have cognitive deficits. The researchers suspect this might be due to a lack of stimulation in childhood, the familial transmission of cognitive challenges, and/or the role of other experiences that often accompany neglect, such as family poverty. Disentangling the mechanisms underlying the observed associations will provide helpful insights to develop effective interventions. 

This research was supported by funding from the National Institute of Justice, the National Institute of Mental Health, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the National Institute on Aging. 

Ends  

Objective and subjective experiences of childhood maltreatment and their relationships with cognitive deficits: a cohort study in the USA (DOI10.1016/ S2215-0366(24)00209-8) (Andrea Danese, Cathy Spatz Widom) was published in Lancet Psychiatry. 

For more information, please contact Patrick O’Brien (Media Manager) 

About King’s College London and the Institute of Psychiatry, Psychology & Neuroscience  

King’s College London is amongst the top 35 universities in the world and top 10 in Europe (THE World University Rankings 2023), and one of England’s oldest and most prestigious universities.  

With an outstanding reputation for world-class teaching and cutting-edge research, King’s maintained its sixth position for ‘research power’ in the UK (2021 Research Excellence Framework).  

King's has more than 33,000 students (including more than 12,800 postgraduates) from some 150 countries worldwide, and some 8,500 staff. The Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s is a leading centre for mental health and neuroscience research in Europe. It produces more highly cited outputs (top 1% citations) on psychiatry and mental health than any other centre (SciVal 2021), and on this metric has risen from 16th (2014) to 4th (2021) in the world for highly cited neuroscience outputs. In the 2021 Research Excellence Framework (REF), 90% of research at the IoPPN was deemed ‘world leading’ or ‘internationally excellent’ (3* and 4*). World-leading research from the IoPPN has made, and continues to make, an impact on how we understand, prevent and treat mental illness, neurological conditions, and other conditions that affect the brain. 

www.kcl.ac.uk/ioppn | Follow @KingsIoPPN on TwitterInstagramFacebook and LinkedIn 

 

How our biases are reflected in how fast we make decisions



Quick decisions more likely flow from biases, while people who take longer make better decisions, according to study led by Utah mathematicians



University of Utah





Quick decisions are more likely influenced by initial biases, resulting in faulty conclusions, while decisions that take time are more likely the result in better information, according to new research led by applied mathematicians at the University of Utah.

A team that included Sean Lawley, an associate professor of mathematics, and three former or current Utah graduate students used the power of numbers to test a decision-making model long used in psychology.

They developed a framework to study the decision-making processes in groups of people holding various levels of bias.

“In large populations, what we see is that slow deciders are making more accurate decisions,” said lead author Samantha Linn, a graduate student in mathematics. “One way to explain that is that they’re taking more time to accumulate more evidence, and they’re getting a complete picture of everything they could possibly understand about the decision before they make it.”

The findings were reported this week in the journal Physical Review E.

The researchers explored how initial biases of individuals, or “agents,” in a group affect the order and accuracy of their choices. The goal was to determine whether a decision was driven mainly by an agent’s predisposition as opposed to accumulated evidence.

They found, in short, the faster the decision was made, the less informed it was and more likely to be wrong.

“Their decisions align with their initial bias, regardless of the underlying truth. In contrast, agents who decide last make decisions as if they were initially unbiased, and hence make better choices,” the study states. “Our analysis shows how bias, information quality, and decision order interact in non-trivial ways to determine the reliability of decisions in a group.”

The team set out to analyze the “drift diffusion model,” which has been well-established in the field of psychology for decades.

They built a model in which groups of agents choose between two options, one reflecting a “correct” decision and the other an “incorrect” decision. The model assumes the agents are acting independently and rationally, that is they are not influenced by each other.

“It really illustrates the power of math that the same equations can describe one phenomenon and then they can describe something completely different,” Lawley said. “The math doesn’t care. The equations don’t care. Seven days or seven apples. The number seven doesn’t care. And in this context, the math doesn’t care if you’re talking about animals searching for food or people making a decision.”

As a researcher, Lawley seeks to apply mathematics to understand a broad range of phenomena. The results can be eye-opening.

In one recent study, for example, he helped develop a model for determining how long someone can delay the onset of menopause through implanting their own preserved ovarian tissue.

In this latest endeavor, Lawley and his colleagues sought to understand the roles of bias and deliberation in how individuals make decisions, whether it’s trivial, like what topping to order on a pizza, or consequential, like which college to attend.

In the team’s model of decision-making in large groups, early decisions tend to be made by agents with the most extreme predispositions.  These choices square with the initial bias regardless of the quality of the evidence the decider had access to.

By contrast, late deciders do not depend on their initial bias; rather their decisions reflect accumulated evidence and are more likely to be “correct.”

“Depending on what decision is being made, if there’s data to inform the parameters, now you have numbers that are going into this that tell you how biased these fast deciders may have been or how unbiased,” Linn said. “Our model is not just about deciding between two things. It can be any number of decisions, and we make very few assumptions.”


The study “Fast decisions reflect biases, slow decisions do not,” was published Aug. 12 in Physical Review E.  Co-authors Bhargav Karamched and Zachary Kilpatrick are former U mathematics graduate students, now on faculty at Florida State University and University of Colorado Boulder, respectively. Co-author KreÅ¡imir Josić is a professor of mathematics at the University of Houston. The scholars’ research is supported by grants from the National Science Foundation and the National Institutes of Health.