Thursday, May 21, 2020

Scientists use ultrasonic mind control on monkeys

Scientists estimate ultrasonic brain manipulation could eventually be used to study and treat decision-making disorders like addiction in humans. Photo by QuinceMedia/Pixabay

May 20 (UPI) -- Scientists have for the first time directed the decision making of monkeys using remote, ultrasonic brain stimulation.

For the study, published Wednesday in the journal Science Advances, researchers had a pair of macaque monkeys participate in a visual test designed to investigate basic decision making.

The monkeys were made to look at a target at the center of a screen before being presented with a second and third target to the left and right sides of the screen, one following the other.

Typically, macaques and other monkeys glance at the target that appears first, but researchers were able to alter the tendency by directing low-intensity ultrasound waves at the frontal eye fields of the two monkeys, the brain region that controls eye movement.

"Brief, low-intensity ultrasound pulses delivered non-invasively into specific brain regions of macaque monkeys influenced their decisions regarding which target to choose," researchers wrote . "The effects were substantial, leading to around a 2:1 bias in choices compared to the default balanced proportion."

Each of the ultrasonic pulses lasted 300 milliseconds and was applied just before the first secondary target appeared on the sides of the screen. The pulses cause brain tissue to vibrate and neurons to fire, altering the neuronal sequences in the targeted brain region.

When researchers directed ultrasonic waves on the monkey's motor cortex, which doesn't control the eye movements or decision making of monkeys, the visual choices of the two monkeys were unaffected.

Though a lot more testing of the technology and its potential is necessary, scientists estimate ultrasonic brain manipulation could eventually be used to study and treat decision-making disorders like addiction in humans.

"There are ... tantalizing opportunities to apply ultrasonic neuromodulation to non-invasively modulate choice behavior in humans, with first applications aimed at determining the set of circuits involved in a given disorder in a given individual," researchers wrote.
STATE SANCTIONED DEATH SQUAD
Colombia civil war survivors outraged by appointment of warlord's son


The son of former warlord Rodrigo Tovar, shown here under arrest in Bogota, Colombia May 13, 2008, was named to lead a program to compensate victims of the country's long civil war Tovar was part of. Photo by Colombia National Police/EPA
May 21 (UPI) -- The Colombian government this week named the son of one of the country's most notorious warlords to run a program meant for victims of its long-running civil war.

Survivors and victims' rights groups expressed outrage with the selection of Jorge Rodrigo Tovar to operate the program run out of the interior ministry created to compensate victims. Tovar's father, Rodrigo Tovar, known as Jorge 40, has been accused of nearly 400 massacres.

Tovar, leader of the Northern Bloc of the United Self-Defense Forces of Colombia (AUC), was blamed for the torture and dismemberment of 60 peasant farmers in 2000 among other crimes. He was extradited to the United States in 2008 and is serving a 16-year sentence for drug trafficking.

"It's not just because he's Jorge 40's son," Colombia Sen. Antonio Sanguino said. "He's always thought of his father as a hero. Totally unacceptable. And now the Duque administration is rewarding him by appointing him director of victims at the interior ministry. How would the victims of the AUC's Northern Bloc feel?"

DEATH SQUAD
The United Self-Defense Forces of Colombia, or AUC, is a government-supported paramilitary militia that helped fight leftist rebels like the Revolutionary Armed Forces of Colombia, of FARC.


Survivors have blamed those paramilitary groups with contributing to the 260,000 who have died over the country's 52-year civil war while displacing more than 7 million.

The younger Tovar, 30, who is an attorney, said he will not leave his post.
"Everything that is going on fills me with the promise to show that I do good work and that the work can speak for me," Tovar told a local magazine.

upi.com/7008846

Global CO2 emissions to drop 4-7% in 2020, but will it matter?

AFP/File / INA FASSBENDERPopulation confinement has led to drastic changes in energy use and CO2 emissions.
Global CO2 emissions from fossil fuels are set to drop by up to seven percent in 2020 because of the coronavirus pandemic, but even this dramatic decline -- the sharpest since WWII -- would barely dent longterm global warming, researchers reported Tuesday.
In early April, coronavirus lockdowns led to a 17 percent reduction worldwide in carbon pollution compared to the same period last year, according to the first peer-reviewed assessment of the pandemic's impact on CO2 emissions, published in Nature Climate Change.
Four countries or blocs -- China, the United States, the European Union and India -- accounted for two-thirds of the downturn across the first four months of 2020, equivalent to more than one billion tonnes of CO2.
Total emissions from industry and energy last year came to a record 37 billion tonnes.
"Population confinement has led to drastic changes in energy use and CO2 emissions," said lead author Corinne Le Quere, a professor at the Tyndall Centre for Climate Change Research at the University of East Anglia.
"These extreme decreases are likely to be temporary, however, as they do not reflect structural changes in the economic, transport or energy systems."
If the global economy recovers to pre-pandemic conditions by mid-June -- an unlikely scenario -- CO2 emissions in 2020 are projected to drop only four percent, Le Quere and her team calculated.
But if lockdown restrictions persist throughout the year, the decline will be around seven percent.
With nearly five million confirmed infections and 320,000 deaths, the COVID-19 pandemic has deflected attention from the climate crisis that dominated global concerns in 2019.
But the climate threat remains, other experts warn.
"This will make barely a dent in the ongoing build-up of carbon dioxide in the atmosphere," said Richard Betts, head of climate impacts research at Britain's Met Office Hadley Centre.
- Like filling a bathtub -
"We need to stop putting it there altogether, not just put it there more slowly," he said.
"It's like we're filling a bath and have turned down the tap slightly -- but not turned it off. The water is still rising, just not as fast."
Earth's average surface temperature has so far risen by one degree Celsius above pre-industrial levels -- enough to amplify deadly droughts, heatwaves and superstorms engorged by rising seas.
AFP/File / Jonathan WALTERIf lockdown restrictions persist throughout the year, the decline will be around seven percent
Under the 2015 Paris climate treaty, nearly 200 nations pledged to cap global warming at "well below" 2C.
But the UN's Intergovernmental Panel on Climate Change (IPCC) subsequently determined that 1.5C is a far safer temperature guardrail.
The pandemic has underscored just how difficult it will be to hit that more ambitious target.
Emissions must fall 7.6 percent -- in line with the worst-case lockdown scenario for 2020 -- every year this decade to ensure the 1.5C cap, unless other means are found to remove carbon from the atmosphere, scientists calculate.
"The pandemic has shown us that major structural changes in the transport and energy systems are required," noted Mark Maslin, a professor of climatology at University College London.
Some experts have suggested the pandemic could speed up that transition.
"Fossil fuels seem to be getting hit harder relative to renewables," Glen Peters, research director of the Center for International Climate Research in Oslo, told AFP.
- Sectors hit unevenly -
"If this (continues) we may come out of COVID with emissions going down, since renewables have been able to take more relative space, pushing out some of the most polluting fossil fuels, especially coal."
But the multi-trillion dollar rescue packages -- especially in the United States and China -- hastily assembled to stave off another Great Depression send mixed signals when it comes to building a green global economy.
"There is a high risk that short-sightedness will lead governments to lose track of the bigger picture and put money into highly polluting sectors that have no place in a zero-carbon society," said Joeri Rogelj, a researcher at Grantham Institute and Imperial College London.
AFP/File / FRED TANNEAUThe pandemic has underscored just how difficult it will be to hit that more ambitious target
Different sectors of the economy have been hit unevenly by measures taken to halt the pandemic, the study revealed.
On April 7 -- the day global CO2 pollution dropped the most -- emissions from land transport accounted for more than 40 percent of the decrease, while industry, electricity generation, and aviation accounted for 25, 19 and 10 percent, respectively.
Calculating global emissions of CO2 and methane -- another potent greenhouse gas -- usually takes months or longer, but methods used in the study could help guide decision-making, the authors said.
"If we can see the effect of a policy in the space of months as opposed to years then we can refine policies more quickly," said Peters.
TRUMP LIES

Trump blames China for 'mass Worldwide killing'

AFP/File / Brendan Smialowski, Fred DUFOURChina's President Xi Jinping and US President Donald Trump are increasingly divided by the coronavirus pandemic
US President Donald Trump on Wednesday again lashed out at China over the coronavirus pandemic, blaming Beijing for "mass Worldwide killing."
His early morning tweet, which also referred to an unidentified "wacko in China," was the latest heated rhetoric from the White House, where Trump is making attacks on Beijing a centerpiece of his November reelection bid.
"It was the 'incompetence of China', and nothing else, that did this mass Worldwide killing," the president tweeted.
The virus first appeared in the Chinese city of Wuhan last December and spread rapidly around the world, killing more than 323,000 people at the latest count, and triggering huge economic damage.
Trump initially played down the seriousness of the threat and said repeatedly he believed China was addressing the outbreak.
He later pivoted to blaming China for allowing the international spread.
The White House has also suggested, without offering evidence so far, that the virus originated in a laboratory and was accidentally released.
Trump has made repeated but vague threats of retaliation against the chief US economic rival.
He has also threatened to break off US funding to the World Health Organization over what he says was its assistance to China in covering up the extent of the outbreak.
The diplomatic rift is rapidly opening just after Trump had been celebrating a truce in his trade war with China and comes after months of effusive praise for his Chinese counterpart Xi Jinping.
- US 'lies' -
Tempers are also fraying in China, where foreign ministry spokesman Zhao Lijian previously provoked Washington's ire by promoting a conspiracy theory that the virus was first brought to China by the US military.
Pushing back at Trump's WHO critcism, Zhao on Wednesday highlighted what he called the "many mistakes and loopholes on the US side, their lies and rumors."
"The US has seemingly forgotten that in the past, US leaders have repeatedly and publicly praised China's anti-epidemic work," Zhao said.
Zhao blamed US politicians "who want to shift the blame but can't shift it away."
During a phone call with Bangladeshi Prime Minister Sheikh Hasina, Xi also appeared to swipe at the United States.
"Xi emphasised that China opposes actions that interfere with international anti-epidemic cooperation and harm the world's –- and especially developing countries' -- efforts to fight the pandemic," state news agency Xinhua reported.
"China is willing to continue to work with the international community, including Bangladesh, to support the WHO's leadership role, promote international joint prevention and control cooperation, and safeguard global public health security," Xi said.
But US secretary of State Mike Pompeo told a news conference on Wednesday that the COVID-19 crisis had ended US illusions of close ties with China, saying "we greatly underestimated the degree to which Beijing is ideologically and politically hostile to free nations."
Pompeo, a close Trump ally, said China was led by a "brutal, authoritarian regime."
"The Chinese Communist Party's response to the COVID-19 outbreak in Wuhan has accelerated our more realistic understanding of Communist China," he said.
"Today, as we all sit here this morning, Beijing continues to deny investigators access to relevant facilities, to withhold live virus samples, to censor discussion on the pandemic within China and much, much more."

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Virus stigma weighs heavily in sub-Saharan Africa
AFP / PIUS UTOMI EKPEIIn Nigeria, public health announcements have hammered home the message that stigmatising survivors of coronavirus is wrong
Landlords evict people from their homes, nurses are abandoned by their husbands and people are spurned just on suspicion of coming into contact with a COVID-19 patient.
Across sub-Saharan Africa, the stigma attached to the coronavirus is so strong that some choose not to seek treatment to avoid facing unbearable hostility.
People suspected of having contracted COVID-19 say they are treated like pariahs: singled out at work, in their neighbourhoods and even in their homes.
Fatou, a Senegalese woman in her twenties who did not use her real name, described her bitter experience about a month ago after coming into contact with a sick person.
She was immediately confined to her room and ostracised by people in her community.
"Messages have been circulating on social media with my first name, surname and address," she said, adding that rumours were spread that she "contracted the virus by sleeping with white people".
Fatou, who was confined to her room until she tested negative, was then forced to spend two weeks in isolation in a hotel despite having no symptoms because the doctors tracking her case had received "anonymous calls", she said.
This at least gave her a respite "from the gossip", she said.
Some 3,000 kilometres (1,800 miles) away in Gabon, Jocelyn, a biologist who tests suspect cases in Libreville, said he is subjected to similar discrimination on a daily basis.
His team tries to keep a low profile when they visit homes, even if it means endangering their own health.
"We put our suits on inside rather than on the front steps," he said.
"The Gabonese people panic at the idea of us coming to their homes," he added.
- Psychological cost -
In neighbouring Cameroon, a landlord evicted a tenant who tested positive for coronavirus, Yap Boum, an epidemiologist in Yaounde, told AFP.
The stigma attached to the virus is not unique to Africa. "But here we tend to be more communal, we know our neighbours," Boum said.
Many people prefer to keep to themselves when they develop symptoms. Some have died because they delayed seeking medical treatment for fear of being associated with the virus, according to Boum, who is the director of Doctors Without Borders' African research centre.
AFP / -Face masks made in Yaounde
"The psychological aspect must be taken into account if we want to win this battle," he said.
Caregivers in particular are often treated like "plague victims", Boum said.
Cameroonian nurses have been left by their husbands, driven out of their homes because they were working in coronavirus units, said Laure Menguene Mviena, who heads a psychological response unit for COVID-19 patients in Yaounde.
"It is urgent to assist them psychologically because if they are mentally and physically exhausted, how will they care for others?" she stressed.
People should realise that the mortality rate is still low in Cameroon, "lower than in Europe," Menguene Mviena said.
Only around 1,400 deaths from the coronavirus have been reported in sub-Saharan Africa.
- Nicknamed 'Corona' -
Some patients continue to be shamed even after they have recovered from the virus, with many believing they are still endangering public health.
After Roselyn Nyambura of Kenya was released from hospital, her neighbours mocked her and stared at her, she said.
Some even went so far as to call her "Corona".
Once people around her had more information about the disease, the scathing comments began to cease.
"With the intervention of elders, local authorities and the church, people have started to understand that it is possible to recover from corona," she said.
The Kenyan government needs to do more to educate people about the virus, she said.
Governments must strike a delicate balance between the need to enforce strict anti-infection measures while tamping down the fearfulness that leads to stigmatisation.
During the Ebola epidemic -- which killed more than one-third of the people it infected in Liberia, Guinea and Sierra Leone in 2014 -- survivors were in a similar position, Boum said.
Recovered patients were issued certificates stating that they did not pose any further risk to the community than other citizens.
In fact, there is little upside to being a coronavirus survivor, notably in the absence of evidence that a healed patient is immune, even temporarily.
In Nigeria, public health announcements have hammered home the message that stigmatising survivors is wrong and that coronavirus "is not a death sentence".
But scepticism persists.
Somalians run into trouble just for wearing a protective mask.
Mohamed Sharif, a driver in Mogadishu, must wear one for work and has noticed that people avoid him and even flee as he approaches.
"Sometimes you are humiliated by others who think because of the mask you have coronavirus," he said. "I remove it sometimes to avoid this humiliation.”
burx-cma/gir/stb/erc/gd
Monkeys develop virus immunity after infection, vaccine: studies
AFP/File / SAM PANTHAKYTwo new studies of rhesus macaque monkeys provide hope that humans can develop protective immunity against coronavirus
Two studies on monkeys published on Wednesday offer hope that humans can develop protective immunity to the novel coronavirus.
The studies, published in the journal Science, looked at a prototype vaccine and whether infection with SARS-CoV-2 provides immunity against re-exposure.
Both questions are critical as researchers tackle the virus, which has infected nearly five million people around the world and caused more than 325,000 deaths.
The studies were carried out on rhesus macaque monkeys to see whether they develop protective virus immunity from natural infection or from a vaccine.
"The global COVID-19 pandemic has made the development of a vaccine a top biomedical priority, but very little is currently known about protective immunity to the SARS-CoV-2 virus," said senior author Dan Barouch, director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center in Boston.
"In these two studies, we demonstrate in rhesus macaques that prototype vaccines protected against SARS-CoV-2 infection and that SARS-CoV-2 infection protected against re-exposure," Barouch said.
In one study carried out by Barouch and other researchers, nine adult rhesus macaque monkeys were infected with the virus.
The monkeys developed COVID-19 symptoms but created protective antibodies and recovered after a few days.
To test their immunity, they were exposed to SARS-CoV-2 again 35 days later for what is called a "re-challenge", and they showed few to no symptoms.
The authors of the study cautioned that further research will be needed because of the "important differences" between SARS-CoV-2 infection in monkeys and humans.
"Rigorous clinical studies will be required to determine whether SARS-CoV-2 infection effectively protects against SARS-CoV-2 re-exposure in humans," they said.
The second study, involving many of the same researchers and led by Jingyou Yu, involved vaccinating 35 adult macaques with DNA vaccine candidates designed to generate protective antibodies.
They were exposed to the coronavirus six weeks later and had developed levels of antibodies in the blood sufficient to neutralize it, the study found.
The levels of antibodies, it said, were similar to those seen in humans recovering from the virus, providing hope that an effective human vaccine can be developed.
"Further research will need to address the important questions of the durability of protective immunity and the optimal vaccine platforms for a SARS-CoV-2 vaccine for humans," the authors of the study said.

UPDATED 
Woman behind ‘Roe v. Wade’ said in a ‘deathbed confession’ that conservatives paid her to lie about her conversion

Published May 19, 2020 By Travis Gettys


“Jane Roe,” the plaintiff in the landmark 1973 Supreme Court ruling legalizing abortion, admitted in a deathbed confession that she faked her conversion later in life to oppose legal abortion.

Norma McCorvey, who died in 2017, became known as Jane Roe after suing for the right to get a legal and safe abortion in Texas, made the stunning confession in the upcoming FX documentary “AKA Jane Roe,” reported The Daily Beast.

“This is my deathbed confession,” McCorvey chuckles in the film.

Director Nick Sweeney asks whether the evangelical movement used her as a trophy, and McCorvey agrees she was “the big fish,” but admits she also got something out of the arrangement.

“I think it was a mutual thing,” she told the filmmaker. “I took their money and they took me out in front of the cameras and told me what to say. That’s what I’d say.”

“I’m a good actress,” she added. “Of course, I’m not acting now.”



Conservatives crowed for years after McCorvey announced that she had renounced being a lesbian and became an anti-abortion, born-again Christian, and actors Jon Voight and 


Stacey Dash starred in a preachy film about her conversion.

But she makes clear in the film, which is out May 22, that she hadn’t really changed her ways.

“I wonder how many abortions Donald Trump is responsible for,” McCorvey said in the film. “I’m sure he’s lost count, if he can count that high.”

“If a young woman wants to have an abortion—fine,” she added. “That’s no skin off my ass. You know, that’s why they call it ‘choice.’ It’s your choice.”




Woman in landmark US abortion case was paid for later activism: documentary
GETTY/AFP/File / TRAVIS LINDQUISTNorma McCorvey (C-Podium), the Roe of Roe v. Wade, speaks on the steps of the US Supreme Court on January 18, 2005 after petitioning the court to reverse its landmark decision that granted women the right to an abortion

The woman at the center of the 1973 Supreme Court decision that legalized abortion in the United States, Roe v Wade, says she was later paid by anti-abortion groups to denounce the landmark ruling, according to a documentary set for release on Friday.

Norma McCorvey was the anonymous "Jane Roe" who went to court in 1969 to challenge laws against abortion after she was barred in the state of Texas from obtaining one.

Her case went all the way to the Supreme Court, which on January 22, 1973 ruled that a woman could legally terminate a pregnancy.

In the 1990s, however, McCorvey became a fervent opponent of abortion, converting to evangelical Protestantism and later Catholicism.

In the documentary "AKA Jane Roe," which airs Friday on the FX network, McCorvey asserts she was paid to be the face of the anti-abortion movement.

"I think it was a mutual thing," she said in a clip from the documentary published in US media. "I took their money and they'd put me out in front of the cameras and tell me what to say. That's what I'd say."
AFP / CHRIS KLEPONIS
Norma McCorvey, who brought the original suit that resulted in the Supreme Court's landmark 1973 ruling granting women the right to abortion, says she was later paid by the anti-abortion movement to denounce the decision, according to a new documentary
"I was a big fish," she told director Nick Sweeny, who met her several months before her death in 2017, at the age of 69.

"It was all an act?" Sweeny asked.

"Yeah, I did it well too. I am a good actress -- of course I'm not acting now," McCorvey replied.

In what she described as a "deathbed confession," McCorvey said, "If a young woman wants to have an abortion, fine. You know, that's no skin off my ass. You know that's why they call it choice, it's your choice."

Since the Supreme Court decision, the right to abortion continues to deeply divide Americans, with many opposing it for religious reasons.

In recent years, some states have passed laws severely restricting access to the procedure, igniting legal battles that seem likely to end up once again before the Supreme Court.

A world redrawn: virus a 'genocide' threat for Amazon, warns Salgado

AFP/File / Sergio LIMAAccording to some estimates, 90 percent of the native population of the Americas was wiped out by disease after the arrival of the first Europeans
Legendary photographer Sebastiao Salgado has warned of a "genocide" of the Amazon's indigenous peoples if the Brazilian government does not do more to protect them from the coronavirus.
The country's far-right president, Jair Bolsonaro -- who has dismissed the virus as a "little flu" -- has long been accused of encouraging loggers and farmers to invade indigenous reserves and of dismantling government agencies set up to protect them.
Brazilian-born Salgado, who shot to fame with his almost biblical images of gold miners in the Amazon, told AFP that "there was a huge risk of a real catastrophe".
"With gold miners, loggers, farmers and religious sects invading their territories... there is a big risk of the coronavirus infecting the indigenous people, who don't have any antibodies."
AFP/File / INA FASSBENDERLegendary photographer Sebastiao Salgado warns the Amazon's indigenous peoples face a "genocide" if the Brazilian government does not do more to protect them from the coronavirus
According to some estimates, 90 percent of the native population of the Americas was wiped out by disease after the arrival of the first Europeans.
Salgado has launched a petition calling for action to protect the Amazonian peoples which has garnered almost a quarter of a million signatures, including Madonna, Oprah Winfrey and Brad Pitt.
He said the risk of genocide was not an exaggeration.
- 'Near collapse' -
"That is what I call it. Genocide is the elimination of an ethnic group and also of its culture.
AFP / MICHAEL DANTASAn indigenous girl from Parque das Tribos community leaves a headdress on the coffin of Chief Messias, 53, of the Kokama tribe who died victim of the new coronavirus in Manaus, Brazil
"I believe that is where the Bolsonaro government is leading us, because their position is 100 percent against the indigenous people."
With hospitals in Sao Paulo, Brazil's biggest city, reported to be at "near collapse" as the country has become the epicentre of the pandemic in South America, Salgado warned that the threat of death was hanging "over a large portion of the population".
"Bolsonaro is against a lockdown, and they do not have the medical infrastructure that we have" in Europe, said Salgado, 76, who has long lived in Paris.
"If the virus gets into the forest, they don't have the means to help. The distances are so huge. The indigenous people will be abandoned," the photographer said.
The virus has already infected 40 indigenous groups, with 537 positive cases and 102 deaths, according to the Brazilian Indigenous Peoples' Association.
And on Tuesday, the indigenous rights group, Forest Guardians, warned that one tribe of hunter gatherers, the Awa Guaja, which traditionally has no contact with the outside world, was in danger of being wiped out because of encroachment by loggers and farmers.
- We need a 'new system' -
Brazil has an estimated 800,000 indigenous people from 300 ethnic groups.
AFP/File / RICARDO OLIVEIRASatere-mawe indigenous men navigate the Ariau river during the COVID-19 novel coronavirus pandemic at the Sahu-Ape community, Amazonas State, Brazil
"If you don't put an end to the invasions of our territory, the uncontacted Awa Guaja people will die," said the Forest Guardians, several of whose members have been murdered in recent months.
Salgado said that the coronavirus was "also a product of our destruction of the environment and the planet".
Yet, he added, it had given us a chance to rethink everything.
"We have become the aliens" living in towns and cities, he said.
"We destroy everything so we can feed it into the cities and keep them going."
He said that humanity needed to have a long hard look at how it was living, and change course.
"We will have so much to do" after the virus, he said.
"We have to create a new and properly productive system... If we go in that direction, we will have to guarantee that a large part of the riches of the planet go towards its reconstruction."

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