Friday, January 15, 2021

Ex-Gov. Rick Snyder pleads not guilty as nine face charges in Flint water crisis

Joe GuillenChristine MacDonaldJennifer Dixon
Detroit Free Press



(Note: Snyder hearing, above, begins at the 27:15 mark in the video)

The criminal investigation into the Flint water crisis burst open in historic fashion on Thursday as Attorney General Dana Nessel’s Office detailed sweeping new indictments against former Gov. Rick Snyder, members of his inner circle and others for their roles in the environmental catastrophe.

The charges include felony charges of obstruction of justice and extortion against Snyder’s former top aide, Richard Baird, and nine counts of involuntary manslaughter each against two former state health officials.

In all, nine people — most of them former government officials — were charged with a total of 42 counts as part of the criminal investigation into the 2014 disastrous switch by a cash-strapped Flint to use its river as its new water supply, which resulted in widespread lead contamination. They were arraigned Thursday morning and have been released after entering not guilty pleas and posting bond, according to court proceedings and the Genesee County Sheriff’s Office.

Snyder appeared in a Flint court Thursday morning and pleaded not guilty to two charges of willful neglect of duty, a misdemeanor.

Despite the lower-level charges compared with other defendants, the case against Snyder marked a significant moment in the state's political history. Snyder is the first Michigan governor or former governor to be charged for alleged criminal conduct while in office.

Supporters of the former Republican governor and his aides decried the prosecution as a reckless overreach fueled by partisanship.

But Snyder's critics say it was he who should have acted sooner when he knew or should have known there was something terribly wrong with the water Flint residents were drinking. Further, it was he who pushed for Michigan's emergency manager law and appointed the Flint overseers who managed the switch of the city's water supply to the Flint River. And it is Snyder, they say, who has given ambiguous and sometimes conflicting accounts about what he knew and when he knew it.

On Thursday, Nessel praised the high-wire prosecutions into the contamination of Flint's drinking water supply led by her Office's Solicitor General Fadwa Hammoud, as well as Wayne County Prosecutor Kym Worthy. Nessel had said earlier that she had walled herself off from the criminal cases, turning her focus instead to ongoing civil cases related to the contamination of Flint's drinking water beginning more than six years ago.

“Solicitor General Hammoud and Prosecutor Worthy’s track records demonstrate their commitment to public service as experienced prosecutors, which is why I appointed them to lead the criminal investigation in the Flint water crisis,” Nessel said in a statement Thursday around noontime. “I trust today’s announcement reflects their professional responsibilities and ethical obligations as the prosecuting authorities in this matter, and that their decisions are based solely on the facts, the law and the evidence.”

The evidence was reviewed by Genesee County Circuit Court Judge David Newblatt, who was appointed as a one-man grand juror to investigate crimes related to the crisis. The indictments followed a year's worth of grand jury proceedings.

The totality of the Flint water catastrophe may never be known, but the failures of public officials who "evaded accountability for far too long" continue to reverberate throughout the community, Hammoud said.

“When an entire city is victimized by the negligence and indifference of those in power, it deserves an uncompromising investigation that holds to account anyone who is criminally culpable. That is what all citizens in this state are entitled to regardless of their ZIP code," Hammoud said at a news conference Thursday.

"Let me be clear, there are no velvet ropes in our criminal justice system. Nobody, no matter how powerful or well-connected is above accountability when they commit a crime," she said.

Years ago, the office of the state's previous attorney general, Bill Schuette, pursued criminal charges against a number of the same defendants charged this week. But in June 2019, Nessel, the newly elected Democrat, upended that effort when her office dismissing all pending criminal charges, saying the initial Flint investigation had been bungled and opting instead to launch a new and expanded probe.

Her actions this week led to charges for the first time against Snyder.

In a remote court appearance Thursday morning whose social distance was necessitated by the novel coronavirus pandemic, Snyder, 62, wore a navy blazer, a light blue collared shirt without a necktie and a gray face mask. He was seated next to his attorney, Brian Lennon, in a Genesee County jail booth as they appeared for the hearing via Zoom. In a separate courtroom, connected by a computer link, a judge presided.

Snyder spoke sparingly during the hearing. His only words were “yes, your honor” in response to the judge’s question of whether he lives in the state. Snyder did not say which city or town.

During Snyder’s arraignment before Genesee District Judge Christopher Odette, Nessel's office sought to restrict Snyder's travel during the case by surrendering his passport because Snyder is a "man of means" with international contacts.

But Odette only ordered Snyder not to leave the state without the court's permission.

"I'm not going to have him surrender his passport on a misdemeanor charge," Odette said.

Odette also set a personal recognizance bond of $10,000 on each charge for Snyder. The former governor walked out of the county sheriff's office after the remote hearing but did not comment to awaiting reporters and photographers.

“The two misdemeanor charges filed today against former Gov. Rick Snyder are wholly without merit and this entire situation is puzzling,” Lennon, Snyder's attorney and partner at Warner Norcross + Judd, said in a statement after the hearing Thursday.

Nessel filed charges against Snyder and at least one other defendant quietly on Wednesday before holding a news conference with her lead prosecutors on Thursday morning.

Genesee County District Court records show the charges against Snyder stem from an alleged offense on April 25, 2014 — the day Flint began using the Flint River as its new water source.

Bacteria in the contaminated water was also blamed for an outbreak of Legionnaires’ disease. Authorities counted at least 90 cases in Genesee County, including 12 deaths. Legionnaires' disease is a severe form of pneumonia and often caught by inhaling the related bacteria from water.

The outbreak was announced by Snyder and his health department director in January 2016, even though some inside the administration later said they knew that cases had been discovered much earlier.

Each charge Snyder faces is a misdemeanor punishable by up to a year in prison or a fine of up to $1,000.

Prosecutors have rarely moved against the state's chief executives in or out of office. In 1975, former Democratic Gov. John Swainson was indicted for bribery while a member of the Michigan Supreme Court. Swainson, who was Michigan governor in 1961 and 1962, was later acquitted of the bribery charge but convicted of perjury. He died in 1994.

New charges in the Flint criminal case mark a dramatic escalation of the prosecution alleging criminal negligence. Some legal and public policy experts said the charges against Snyder were appropriate while expressing concern that the indictments could have some unintended consequences.

Paul Mohai, a professor at the University of Michigan’s School for Environment and Sustainability, said the charges against Snyder and the other officials are a step in the right direction toward environmental justice for the people of Flint. The city’s switch to the Flint River as its source of drinking water had disastrous consequences and “people should be held accountable for that,” Mohai said
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Compounding the anger of the people of Flint, according to Mohai, were the state officials who chose to deny the problem and dismiss the evidence coming from the majority-Black city for more than a year.

Sara Hughes, an assistant professor at the University of Michigan’s School for Environment and Sustainability who studies urban policy, said that there is concern that the indictments could result in tightened governmental immunity protections and prompt public officials to “circle the wagons.”

“That would be a terrible outcome from this,” Hughes said. Instead, she hopes the case leads to politicians being held to a “higher standard” based on the public’s values.

Snyder, a Republican who has been out of office for two years, was governor when state-appointed managers in Flint switched the city’s water to the Flint River in 2014 as a cost-saving step while a pipeline was being built to Lake Huron. The water, however, was not treated to reduce corrosion — a disastrous decision affirmed by state regulators that caused lead to leach from old pipes and poison the distribution system used by nearly 100,000 residents.

Residents complained about discolored and foul-smelling water for over a year before the state acknowledged the problem. Flint switched back to Detroit water in October 2015, but the risk remained because of damage to the city's water infrastructure.

The prosecution also widened Thursday to include more serious charges against two of Snyder's former top aides as well as his former health department director.

Baird, a top aide to Snyder, has now been charged with four felonies, including extortion and obstruction of justice. He pleaded not guilty before Genesee Circuit Judge Elizabeth Kelly on Thursday  
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According to his indictment, Baird, 64, was charged with perjury for making a false statement during an interview with the attorney general’s office on March 1, 2017. The obstruction of justice charge stems from an alleged attempt to influence or interfere with the water crisis legal proceedings. Baird’s extortion charge is related to an alleged threat to a leader of the state-appointed Flint Area Community Health and Environmental Partnership during the organization’s investigation into the source of the Legionnaires’ disease outbreak associated with the contaminated water.

Baird’s attorney Randall Levine said in a statement after the arraignment that the accusations are baseless and politically motivated.

“Mr. Baird is innocent of any wrongdoing and is being unfairly prosecuted by the state’s Democratic attorney general,” Levine said.

Kelly ordered Baird to surrender his passport, although he is allowed to travel for work between Michigan and Illinois, where he lives in Chicago. Baird is a member of the board of regents at Eastern Michigan University, according to Levine.

“The people of Flint are justifiably upset and angry about what happened in Flint,” Levine said. “Their government failed them at so many levels. However, the evidence will show that Rich Baird is not responsible for what occurred to the folks in the town where he grew up. I expect that he will be vindicated.”

Another member of Snyder's inner circle, Jarrod Agen, the governor's former communications director and chief of staff, was also among the newly charged, with one count of perjury during an investigative subpoena examination, a felony punishable by up to 15 years in prison.

Through his attorney, Agen, 43, entered a plea of not guilty.

After working for Snyder, Agen became Vice President Mike Pence’s communications director and is now a spokesman for Lockheed Martin, a defense contractor. Agen’s attorney J. Benjamin Dolan did not immediately return a call for comment.

Former health department director Nick Lyon, 52, was also charged again Thursday morning with nine counts of involuntary manslaughter, a felony punishable by up to 15 years in prison. He also faces a misdemeanor charge of willful neglect of duty. He pleaded not guilty to all charges.

The manslaughter charges Lyon faces, according to his indictment, are for causing the deaths of nine people through the “grossly negligent failure” to protect the health of Michigan citizens
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The judge set a $200,000 cash surety bond for Lyon on all the charges. His lawyer Charles Chamberlain said his client is innocent and called it a “dangerous day for state employees”

“Our hearts go out to Flint citizens who have endured the fallout from that decision,” Chamberlain said in a written statement. “But it does not help the people of Flint — or our criminal justice system — for the State to charge innocent people with crimes.”

“He did not make the decision to switch the water supply and had nothing to do with handling the water. Everything he did as director of the Michigan Department of Health & Human Services (MDHHS) he did based on the advice of highly trained epidemiologists and public health scientists and experts who themselves were looking at the science and following the data. It’s apparent that once again, the Attorney General has ignored the facts and the evidence.”

Also charged with nine felony counts of involuntary manslaughter was Dr. Eden Wells, 58, the state's former chief medical executive. She was also charged with two felony counts of misconduct in office and a misdemeanor charge of willful neglect of duty. The potential penalty for each charge is: up to 15 years in prison on the involuntary manslaughter charges, up to five years in prison on the misconduct in office charges and up to one year in prison on the misdemeanor

During her court hearing Thursday in Flint, she asked the court to enter a not guilty plea. The judge allowed her to continue to live in Maine while she faces the charges.

There were others accused of related crimes, too: former Flint Department of Public Works Director Howard Croft; two former Flint emergency managers, Darnell Earley and Gerald Ambrose, and Nancy Peeler, a manager in the Michigan Department of Health and Human Services’ early childhood health section.




Several of those charged Thursday had also been charged in the state’s first effort to prosecute those responsible.

Lyon was charged previously with one count of involuntary manslaughter. Wells was charged with obstruction of justice and lying to a police officer. Earley was charged with false pretenses and conspiracy, both 20-year felonies, and other charges. Ambrose was charged with false pretenses, conspiracy, misconduct in office and willful neglect of duty. Croft was charged with conspiracy and false pretenses.

The latest charges revealed on Thursday have been expected for days, but Nessel's Office refused to provide any information about the charges until Thursday. Wayne County Prosecutor Worthy said the state's grand jury laws require such secrecy.

Worthy said any suggestion that the attorney general's office withheld information is disingenuous.

"Had we disclosed this information from the grand jury in violation of these secrecy provisions that I’ve outlined, it would not only perhaps jeopardized our investigation but it would’ve been a crime," Worthy said.

It is unclear how much the years-long investigation has cost so far.

"We never put a dollar value on this investigation," Hammoud said.


Some community and religious leaders welcomed the news about the revived prosecutions in the Flint water case, especially charges brought against the former governor.

"Snyder did not protect and serve the people. He did not look out for our well-being, and for that he should be held accountable," Bishop Bernadel Jefferson of the Faith Deliverance Center in Flint said in a statement.

Eileen Hayes, executive director of Michigan Faith in Action, called Nessel's expanded prosecutions "a step in the right direction."

"It felt as though the governor was getting off scot-free and that other players who were also bad actors were getting away with it too. The idea that now, something is going to happen — there is some solace in that," Hayes said in a statement.

Flint Mayor Sheldon Neeley said in a statement that the new charges confirm there were multiple levels of wrongdoing to the community.

“The Flint community has waited nearly seven years for these steps toward justice,” Neeley said.
Summary of defendants and charges:

All nine defendants arraigned Thursday morning have been released after posting bond, according to the Genesee County Sheriff’s Office.

Jarrod Agen – former Director of Communications and former Chief of Staff, Executive Office of Gov. Rick Snyder; one count of perjury – a 15-year felony

Gerald Ambrose – former City of Flint Emergency Manager; four counts of misconduct in office – each a five-year felony and/or $10,000 fine

Richard Baird – former Transformation Manager and Senior Adviser, Executive Office of Gov. Snyder; one count of perjury – a 15-year felony; one count of official misconduct in office – a five-year felony and/or $10,000 fine; one count of obstruction of justice – a five-year felony and/or $10,000 fine; and one count of extortion – a 20-year felony and/or $10,000 fine

Howard Croft – former Director of the City of Flint Department of Public Works; two counts of willful neglect of duty – each a one-year misdemeanor and/or $1,000 fine

Darnell Earley – former City of Flint Emergency Manager; three counts of misconduct in office – each a five-year felony and/or $10,000 fine

Nicolas Lyon – former Director, Michigan Department of Health and Human Services; nine counts of involuntary manslaughter – each a 15-year felony and/or $7,500 fine; and one count of willful neglect of duty – a one-year misdemeanor and/or $1,000 fine

Nancy Peeler – Early Childhood Health Section Manager, Michigan Department of Health and Human Services; two counts of misconduct in office – each a five-year felony and/or $10,000 fine; and one count of willful neglect of duty – a one-year misdemeanor and/or $1,000 fine

Richard Snyder – former Governor of Michigan; two counts of willful neglect of duty – each a one-year misdemeanor and/or $1,000 fine

Eden Wells – former Chief Medical Executive, Michigan Department of Health and Human Services; nine counts of involuntary manslaughter – each a 15-year felony and/or $7,500 fine; two counts of misconduct in office – each a five-year felony and/or $10,000 fine; and one count of willful neglect of duty – a one-year misdemeanor and/or $1,000 fine

Staff writer Paul Egan contributed to this

Low cost chlorine dispensing device improves tap water safety in low-resource regions

Engineers invent device that requires no electricity or moving parts, lets users collect water as they usually do

TUFTS UNIVERSITY

Research News

IMAGE

IMAGE: THE CHLORINE TREATMENT DEVICE REQUIRES LITTLE MAINTENANCE AND NO CHANGE IN COLLECTION OF WATER FROM THE TAP view more 

CREDIT: AMY PICKERING

MEDFORD/SOMERVILLE (January 14, 2021) - A team of researchers led by engineers at Tufts University's School of Engineering and Stanford University's Program on Water, Health and Development have developed a novel and inexpensive chlorine dispensing device that can improve the safety of drinking water in regions of the world that lack financial resources and adequate infrastructure. With no moving parts, no need for electricity, and little need for maintenance, the device releases measured quantities of chlorine into the water just before it exits the tap. It provides a quick and easy way to eliminate water-borne pathogens and reduce the spread of high mortality diseases such as cholera, typhoid fever and diarrhea.

According to the CDC, more than 1.6 million people die from diarrheal diseases every year and half of those are children. The authors suggest that the solution to this problem could be relatively simple.

In communities and regions that do not have the resources to build water treatment plants and distribution infrastructure, the researchers found that the device can provide an effective, alternative means of water treatment at the point of collection. The device was installed and tested at several water collection stations, or kiosks, across rural areas in Kenya.

The study, which also looks at the economic feasibility and local demand for the system, was published today in the journal NPJ Clean Water.

"The idea we pursued was to minimize the user burden by automating water treatment at the point of collection," said Amy J. Pickering, former professor of civil and environmental engineering at Tufts (now at Stanford) and corresponding author of the study. "Clean water is central to improving human health and alleviating poverty. Our goal was to design a chlorine doser that could fit onto any tap, allowing for wide-scale implementation and increasing accessibility to a higher-level of safe water service."

Water is a simple substance, but a complex global health issue in both its availability and quality. Although it has long been a focus of the World Health Organization and other NGO's, 2.1 billion people still lack access to safe water at home (WHO). In areas of the world where finances and infrastructure are scarce, water may be delivered to communities by pipe, boreholes or tube wells, dug wells, and springs. Unfortunately, 29 percent of the global population uses a source that fails to meet the Sustainable Development Goal (SDG) criteria for safely managed water - accessible and available when needed, and free from fecal and chemical contamination. In many places, access to safe water is out of reach due to the lack of available funds to create and support water treatment facilities.

The device works on the principle of a physical phenomenon in fluid dynamics called the Venturi effect, in which a non-compressible fluid flows at a faster rate when it runs from a wider to a narrower passage. In the device, the water passes through a so-called pinch valve. The fast-moving water stream draws in chlorine from a tube attached to the pinch valve. A needle valve controls the rate and thus amount of chlorine flowing into the water stream. The simple design could allow the device to be manufactured for $35 USD at scale.

"Rather than just assume we made something that was easier to use, we conducted user surveys and tracked the performance of the devices over time," said study co-author Jenna Davis, a professor of civil and environmental engineering at Stanford, director of Stanford's Program on Water, Health and Development, and co-PI of the Lotus Water project. This research is an extension of Lotus Water, which aims to provide reliable and affordable disinfection services for communities most at risk of waterborne illness.

A six-month evaluation in Kenya revealed stable operation of six of seven installed devices; one malfunctioned due to accumulation of iron deposits, a problem likely solvable with a pre-filter. Six of the seven sites were able to maintain payment for and upkeep of the device, and 86.2 percent of 167 samples taken from the devices throughout the period showed chlorine above the WHO recommended minimum level to ensure safe water, and below a threshold determined for acceptable taste. Technical adjustments were required in less than 5 percent of visits by managers of the kiosks. In a survey, more than 90 percent of users said they were satisfied with the quality of the water and operation of the device.

"Other devices and methods have been used to treat water at the point of collection," said Julie Powers, PhD student at Tufts School of Engineering and first author of the study. "but the Venturi has several advantages. Perhaps most importantly, it doesn't change the way people collect their water or how long it takes - there's no need for users to determine the correct dosing or spend extra time- just turn on the tap. Our hope is the low cost and high convenience will encourage widespread adoption that can lead to improved public health."

Future work examining the effect of the in-line chlorination device on diarrhea, enteric infections, and child mortality could further catalyze investment and scaling up this technology, said Powers.

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Funding for the development of the device and the study was provided by the Stanford Woods Institute for the Environment at Stanford University and the Stanford Institute for Innovation in Developing Economies.

Powers, J.E., McMurry, C., Gannon, S., Drolet, A., Oremo, J., Klein, L., Crider, Y., Davis, J., and Pickering, A.J. "Design, technical performance and demand for a novel in-line Venturi chlorine doser to increase access to safe drinking water in low-income settings." NPJ Clean Water. 18 Decenber 2020; DOI: 10.1038/s41545-020-00091-1

About Tufts University

Tufts University, located on campuses in Boston, Medford/Somerville and Grafton, Massachusetts, and in Talloires, France, is recognized among the premier research universities in the United States. Tufts enjoys a global reputation for academic excellence and for the preparation of students as leaders in a wide range of professions. A growing number of innovative teaching and research initiatives span all Tufts campuses, and collaboration among the faculty and students in the undergraduate, graduate and professional programs across the university's schools is widely encouraged.

Water and gender equality

Stanford researchers find installing piped water near homes promotes gender equality and improves well-being in rural Zambia

STANFORD UNIVERSITY

Research News

Water isn't just crucial for life, it's fundamental to increasing opportunities for women and girls in rural areas across the globe. A new Stanford study reveals how bringing piped water closer to remote households in Zambia dramatically improves the lives of women and girls, while also improving economic opportunities, food security and well-being for entire households. The research, recently published in Social Science & Medicine, could spur governments and NGOs to more carefully evaluate the costs and benefits of piped water as an alternative to less accessible communal water sources.

"Switching from the village borehole to piped supply saved almost 200 hours of fetching time per year for a typical household," said study senior author Jenna Davis, a professor of civil and environmental engineering at Stanford and director of Stanford's Program on Water, Health and Development. "This is a substantial benefit, most of which accrued to women and girls."

Globally, about 844 million people live without safe, accessible water for drinking, cooking, cleaning, hygiene and food production - the linchpin of healthy, prosperous communities. Just 12 percent of the rural population in sub-Saharan Africa has water piped to their home. Instead, families collect water from distant, shared sources, with women and girls overwhelmingly responsible for performing the time-consuming and arduous chore of carrying containers that average about 40 pounds each. Dedicating a large chunk of their day to water fetching takes time away from activities such as childcare, housework, hygiene, outside employment, education and leisure.

"Addressing this problem provides the time and water for women and girls to invest in their household's health and economic development, in whatever way they see fit," said lead author James Winter, who recently defended his PhD in civil and environmental engineering at Stanford.

Over the past several decades, national governments and international aid groups have spent hundreds of millions of dollars installing basic water sources, such as wells and handpumps. However, many of these sources are still far from users' homes, resulting in long journeys to fetch water. Previous studies have shown water fetching can harm both mental and physical well-being, while piped water at home can increase water for hygiene and livelihoods, improve food production and decrease infectious disease prevalence.

Yet despite this finding, piped water installations in sub-Saharan Africa have increased by a mere 2 percentage points since 2007. Investing resources into high-quality piped water sources that are dramatically closer to rural households could thus be a more effective route to providing safe, accessible and affordable drinking water for all.

For their study, the researchers examined less frequently measured aspects of well-being - including time savings, economic opportunity and nutritional security - that can be gained through increased access to reliable, easily accessible water. To do this, the team followed four rural villages within Zambia's southern province that had similar populations and access to school, markets and health care facilities. Halfway through the study, two of the villages received piped water to their yard, reducing the distance of their water source to just 15 meters.

Each village was surveyed at the beginning, middle and end of the study, with a team of Zambian interviewers conducting a total of 434 household surveys. They collected information on the time spent fetching water, the amount of water used for domestic tasks (cooking and cleaning) and productive uses (watering gardens, brick making or animal husbandry), and the frequency of these activities. A subset of female respondents wore GPS tracking devices to measure walking speeds and distance to water sources. Water meters were used to validate water consumption information.

The researchers found households with piped water spent 80 percent less time fetching water, representing a savings of close to four hours per week. The vast majority of these time savings accrued to women and girls, confirming that females disproportionately benefit from piped water interventions. These time savings were spent gardening, performing other household chores, caring for children or working outside of the home selling products such as fried buns or charcoal. These families also reported being happier, healthier and less worried.

Water consumption, especially for productive purposes, also increased. Households with piped water were over four times more likely to grow a garden, and garden sizes more than doubled over the course of the study. Furthermore, a larger variety of crops were harvested and households reported both selling and consuming this produce, with plans to expand their crop sales in the coming years.

While the accumulated benefits are impressive, they may actually understate the potential time savings of piped water interventions. At the start of the study, households in all four villages lived just a five-minute walk from their primary water source. On average, rural Zambian households spend about double that time walking to their water source, along with additional time waiting in line and filling water containers. The researchers point out that introducing piped water near homes elsewhere in Zambia could save the average rural household 32 hours per month, which is almost twice the amount of time recouped by households in this instance.

Of course, a piped water infrastructure does have higher upfront costs, which could discourage government and NGO investments. Poverty poses a major barrier when it comes to water access, and with most of the world's poorest countries in sub-Saharan Africa, more research is needed to understand what is needed for communities to sustain piped water networks.

"The benefits we see here make it crucial for future work to understand how these systems can be operated and maintained in a financially sustainable way, even in geographically isolated, rural communities," said Winter.

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Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

Accounting for the gaps in ancient food webs

SANTA FE INSTITUTE

Research News

IMAGE

IMAGE: THE BURGESS SHALE FOOD WEB IS ONE OF EIGHT ANCIENT FOOD WEBS THAT WERE ANALYZED FOR SIMILARITIES. view more 

CREDIT: JENNIFER DUNNE

If you want to understand an ecosystem, look at what the species within it eat. In studying food webs -- how animals and plants in a community are connected through their dietary preferences -- ecologists can piece together how energy flows through an ecosystem and how stable it is to climate change and other disturbances. Studying ancient food webs can help scientists reconstruct communities of species, many long extinct, and even use those insights to figure out how modern-day communities might change in the future. There's just one problem: only some species left enough of a trace for scientists to find eons later, leaving large gaps in the fossil record -- and researchers' ability to piece together the food webs from the past.

"When things die and get preserved as fossils, all the stuff that isn't bones and teeth and shells just decays," says the Santa Fe Institute's Vice President for Science Jennifer Dunne, a veteran food web researcher. "Organisms that are primarily soft-bodied, they usually just disappear from the record altogether."

A new paper by paleoecologist Jack Shaw, a PhD student at Yale University who led the study, Dunne and other researchers shines a light on those gaps and points the way to how to account for them. "The missing components of the fossil record -- such as soft-bodied organisms -- represent huge gaps in understanding ancient ecology, but we haven't thought extensively about how those gaps are affecting our inferences," Shaw says. "We're taking the fossil record at face value without critically thinking about how face value might not be robust and accurate."

Focusing on the absence of soft-bodied taxa in the fossil record, the study, published in Paleobiology on January 14, notes that accounting for these data gaps is vital for forming a more accurate picture of ancient food webs. By only looking at fossilized taxa, without accounting for the loss of soft-bodied organisms to the sands of time, for example, researchers might make the mistake of assuming the ecological community was structured differently and less stable than it actually was.

But by drawing on network theory, the researchers were able to show that the inclusion of soft-bodied organisms is vital for realistic depictions of ancient food webs. They found that ecological differences between soft- and hard-bodied taxa appear in the record of an Early Eocene food web, but not in much older Cambrian food webs, suggesting that the differences between the groups have existed for at least 48 million years.

"Geologists and biologists assume that soft-bodied and hard-bodied things have distinct life habits -- where they live or who they eat -- but we actually quantify it here using network analysis," Shaw says.

He and Dunne hope the study will help strengthen future research in the burgeoning field of ancient food web reconstruction. "This work is really important, because it's grappling with some of the fundamental uncertainty relating to the fossil record," says Dunne.

"The methodology can be applied to various other types of biases," not just the soft-bodied organism related bias, Shaw notes. "We're hoping to start being more critical of ancient food webs and perhaps opening them up to being more robust. A better grasp on how ancient food webs were affected by perturbations will allow us to make better predictions of what future ecosystems may look like."


Overactive food quality control system triggers food allergies, Yale scientists say

YALE UNIVERSITY

Research News

Food allergies have been increasing dramatically across the developed world for more than 30 years. For instance, as many as 8% of children in the U.S. now experience potentially lethal immune system responses to such foods as milk, tree nuts, fish and shellfish. But scientists have struggled to explain why that is. A prevailing theory has been that food allergies arise because of an absence of natural pathogens such as parasites in the modern environment, which in turn makes the part of the immune system that evolved to deal with such natural threats hypersensitive to certain foods.

In a paper published Jan. 14 in the journal Cell, four Yale immunobiologists propose an expanded explanation for the rise of food allergies -- the exaggerated activation of our food quality control system, a complex and highly evolved program designed to protect us against eating harmful foods. The presence of unnatural substances, including processed food, or environmental chemicals, such as dishwashing detergent, in the modern environment, as well as the absence of natural microbial exposure, play a role in disrupting this food quality control program, they argue.

The theory can lay the groundwork for future treatment or prevention of food allergies, the scientists suggest.

"We can't devise ways to prevent or treat food allergies until we fully understand underlying biology," said co-author Ruslan Medzhitov, Sterling Professor of Immunobiology and investigator for the Howard Hughes Medical Institute. "You can't be a good car mechanic if you don't know how a normal car works."

The quality food control program present in the biology of all animals includes sensory guardians -- if something smells or tastes bad, we don't eat it. And there are sentinels in the gut -- if we consume toxins, they are detected and expelled. In the latter case, a part of the immune system as well as parasympathetic arm of the nervous system also mobilize to help neutralize the threat.

This type of immune system response triggers allergies, including food allergies, a fact that gave rise to the so-called "hygiene hypothesis" of food allergies. The lack of natural threats such as parasites made this portion of the immune system hypersensitive and more likely to respond to generally innocuous proteins found in certain food groups, the theory holds. This helped explain why people living in rural areas of the world are much less likely to develop food allergies than those living in more urban areas.

However, food allergies have continued to rise dramatically long after elimination of parasites in the developed world, Medzhitov noted. So the Yale team now theorizes that other environmental factors influenced activity within the natural food quality control system and contributed to immune system hypersensitivity to certain food allergens.

"One factor is increased use of hygiene products and overuse of antibiotics and, secondly, a change in diet and the increased consumption of processed food with reduced exposure to naturally grown food and changed composition of the gut microbiome," Medzhitov said. "Finally, the introduction of food preservatives and environmental chemicals such as dishwashing detergents introduced novel elements for immune system to monitor." Collectively, these changes in the environment effectively trigger food quality control responses making the immune system react to food proteins the way it would react to toxic substances, the team argues.

"It's guilt by association," Medzhitov said.

Food allergies are no different than many other diseases, which are caused by abnormal versions of normal biological responses, he said. Understanding the underlying biology of normal processes such as food quality control system should help researchers identify potential culprits not only in food allergies, but other diseases as well, the authors argue.

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Yale co-authors are Esther Florsheim, a former postdoctoral research associate, Zuri Sullivan, a postdoctoral associate, and William Khoury-Hanold, a postdoctoral fellow, of the Yale Department of Immunolog

The regulatory network of sugar and organic acid in watermelon fruit is revealed

NANJING AGRICULTURAL UNIVERSITY THE ACADEMY OF SCIENCE

Research News

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IMAGE: FIGURE 1 GENE NETWORKS AND KEY CANDIDATE GENES INVOLVED IN SUGAR AND ORGANIC ACID REGULATION DURING WATERMELON FRUIT DEVELOPMENT view more 

CREDIT: ZHENGZHOU FRUIT RESEARCH INSTITUTE

Recently, the innovation project watermelon and melon cultivation and physiology team of Zhengzhou Fruit Research Institute has made new progress in the metabolism regulation of sugar and organic acid in watermelon fruit. The changes of sugar and organic acid during the fruit development were analyzed and the key gene networks controlling the metabolism of sugar and organic acid during the fruit development were identified. These results provided a theoretical basis for watermelon quality breeding, which had important scientific significance for the development of watermelon industry and the improvement of watermelon breeding level in China. The related research results were published in the journals of Horticulture Research and Scientia Horticulturae.

The sensory quality of watermelon fruit is determined by the content of sugar and organic acid, which determines the taste of watermelon during the development and maturation of watermelon fruit. The sweet watermelon '203Z' and sour watermelon 'SrW' of its isogenic line were used as materials, the genes and gene networks co-expressed with glycolic acid metabolism were searched through WGCNA analysis of transcriptional and metabolite data. Three gene expression networks were identified, including 2443 genes that were highly correlated with sugar and organic acid metabolism in watermelon fruits. Seven key genes involved in sugar and organic acid metabolism of watermelon fruits were screened by significance and qRT-PCR analysis. Among them, Cla97C01G000640, Cla97C05G087120 and Cla97C01G018840 were sugar transporters. Cla97C03G064990 was a sucrose synthase. Cla97C07G128420, Cla97C03G068240 and Cla97C01G008870 were highly correlated with malic acid and citric acid, which were the transporters and regulators of malic acid and citric acid. These genes were verified in the natural population, and the results showed that the expressions of these 7 genes were significantly positively correlated with the contents of sugar and organic acid in watermelon fruit.

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These researches were funded by the Agricultural Science and Technology Innovation Program (CAAS-ASTIP-2016-ZFRI-07), National Key R&D Program of China (2018YFD0100704), the China Agriculture Research System (CARS-25-03) and the National Nature Science Foundation of China (31672178 and 31471893).

Eating omega-3 fat helps hibernating Arctic ground squirrels warm up during deep cold

UNIVERSITY OF ALASKA FAIRBANKS

Research News

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IMAGE: TWO WILD ARCTIC GROUND SQUIRRELS TOUCH NOSES IN THE NORTHERN BROOKS RANGE DURING SUMMER. view more 

CREDIT: PHOTO BY RHIANNAN WILLIAM

By feeding arctic ground squirrels special diets, researchers have found that omega-3 fatty acids, common in flax seed and fish oil, help keep the animals warmer in deep hibernation.

A University of Alaska Fairbanks-led study fed ground squirrels either a diet high in omega-3s or a normal laboratory diet, and measured how the animals hibernated afterward. Researchers found that the omega-3 diet helped the animals hibernate a little warmer than normal without negatively affecting hibernation. The omega-3 diets also increased the amount of a heat-producing fat, called brown adipose tissue, the animals pack on.

The discovery could add more understanding about how hibernation works and why animals eat some types of foods. The study was published Jan. 14 in the journal Scientific Reports.

"Arctic ground squirrels have an innate ability to withstand harsh subzero temperatures for an incredible amount of time," says Monica Mikes, who at the time of the study was an undergraduate researcher at UAF and a scholar in the university's Biomedical Learning and Student Training program.

Mikes, who also co-designed the study, noted that the animals are able to take their body temperature below freezing. How hibernators regulate body temperature has fascinated researchers for over a century. The type of fat they eat might have something to do with that.

Recent studies have found that omega-3s can affect metabolism in nonhibernating animals. Since wild hibernators are known to eat diets rich in omega-3 foods, the researchers wanted to know if those animals benefited from eating those diets.

"Fat is incredibly important in hibernation," said lead author Sarah Rice, who was a Ph.D. student at UAF's Institute of Arctic Biology at the time of the study. "Not only do these animals live off their fat stores, but the more people study specific types of fat, the more they realize specific types of fat can help regulate and signal the body to do certain things."

Scientists know hibernators specifically seek out and store polyunsaturated fatty acids, known as PUFAs, prior to hibernation. While omega-6 PUFAs have been well-studied in hibernation and are known to reduce temperature, omega-3s have been less studied.

As arctic ground squirrels experience extreme cold in their natural dens, eating more omega-3s to help increase brown adipose tissue may help defend against extreme cold in the wild. Researchers in this study did not investigate which foods might provide ground squirrels in the wild with such omega-3s.

"People know eating omega-3s like fish oil is good for them. Apparently, squirrels may realize this too, and it may have specialized effects for hibernators," Rice said.

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Other contributors to the paper include Kelly Drew at the UAF Center for Transformative Research in Metabolism; Julie Reisz, Sarah Gehrke and Angelo D'Alessandro at the University of Colorado's Department of Biochemistry and Molecular Genetics; Doug Bibus at Lipid Technologies; and Evgeny Berdyshev and Irina Bronova at National Jewish Health, a Denver-based hospital.

Toadlet peptide transforms into a deadly weapon against bacteria

EUROPEAN MOLECULAR BIOLOGY LABORATORY

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IMAGE: THE PEPTIDE UPERIN 3.5 IS SECRETED BY THE AUSTRALIAN TOADLET'S SKIN. WHEN EXPOSED TO BACTERIAL MEMBRANES, IT RAPIDLY CHANGES ITS STRUCTURE AND TRANSFORMS INTO A DEADLY ANTIMICROBIAL WEAPON. THE PICTURES... view more 

CREDIT: NIR SALINAS/TECHNION

An antibacterial peptide that turns on and off

The researchers solved the 3D molecular structure of an antibacterial peptide named uperin 3.5, which is secreted on the skin of the Australian toadlet (Uperoleia mjobergii) as part of its immune system. They found that the peptide self-assembles into a unique fibrous structure, which via a sophisticated structural adaptation mechanism can change its form in the presence of bacteria to protect the toadlet from infections. This provides unique atomic-level evidence explaining a regulation mechanism of an antimicrobial peptide.

The antibacterial fibrils on the toadlet's skin have a structure that is reminiscent of amyloid fibrils, which are a hallmark of neurodegenerative diseases, such as Alzheimer's and Parkinson's. Although amyloid fibrils have been considered pathogenic for decades, it has recently been discovered that certain amyloid fibrils can benefit the organisms that produce them, from human to microbes. For example, certain bacteria produce such fibrils to fight human immune cells.

The findings suggest that the antibacterial peptide secreted on the toadlet's skin self-assembles into a "dormant" configuration in the form of highly stable amyloid fibrils, which scientists describe as a cross-β conformation. These fibrils serve as a reservoir of potential attacker molecules that can be activated when bacteria are present. Once the peptide encounters the bacterial membrane, it changes its molecular configuration to a less compact cross-α form, and transforms into a deadly weapon. "This is a sophisticated protective mechanism of the toadlet, induced by the attacking bacteria themselves," says structural biologist Meytal Landau, the lead author of this study. "This is a unique example of an evolutionary design of switchable supramolecular structures to control activity."

Potential for future medical applications

Antimicrobial peptides are found in all kingdoms of life, and thus are hypothesised to be commonly used as weapons in nature, occasionally effective in killing not only bacteria, but also cancer cells. Moreover, the unique amyloid-like properties of the toadlet's antibacterial peptide, discovered in this study, shed light on potential physiological properties of amyloid fibrils associated with neurodegenerative and systemic disorders.

The researchers hope that their discovery will lead to medical and technological applications, e.g. development of synthetic antimicrobial peptides that would be activated only in the presence of bacteria. Synthetic peptides of this kind could also serve as a stable coating for medical devices or implants, or even in industrial equipment that requires sterile conditions.

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The study is a result of a collaboration between scientists at EMBL Hamburg and Technion, and groups in Israel and Spain. It is an example of EMBL's approach to life science research in its next scientific Programme Molecules to Ecosystems. EMBL will integrate interdisciplinary approaches to understand the molecular basis of life in the context of environmental changes, and to provide translational potential to support advances in human and planetary health.

Micro-climate moulds and reshapes northern insect communities, herbivory and predation

UNIVERSITY OF HELSINKI

Research News

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IMAGE: THE ADVECTION FOG OFTEN FILLS THE VALLEY FLOOR IN THE SPRING, BEING ONE OF THE FACTORS AFFECTING THE MICRO-CLIMATE ENCOUNTERED BY THE INSECTS. view more 

CREDIT: TUOMAS KANKAANPAA

Climate and changes in it have direct impacts on species of plant and animals - but climate may also shape more complex biological systems like food webs. Now a research group from the University of Helsinki has investigated how micro-climate shapes each level of the ecosystem, from species' abundances in predator communities to parasitism rates in key herbivores, and ultimately to damage suffered by plants. The results reveal how climate change may drastically reshape northern ecosystems.

Understanding the impact of climatic conditions on species interactions is imperative, as these interactions include such potent ecological forces as herbivory, pollination and parasitism.

Lead researcher Tuomas Kankaanpaa from the Faculty of Agriculture and Forestry, University of Helsinki, investigated how insect communities are assembled along micro-climatic gradients found on a mountainside in Northeast Greenland. He then compared this variation in environmental conditions to variation in the structure and function of different compartments of a food web. This web consists of a flowering plant as the primary producer (mountain avens), of moth larvae feeding on the flowers as consumers, and of parasitic wasps and flies, which, in turn, use moth larvae as living nurseries for their own offspring.

The study identified the micro-climate as an important factor in determining the local structure of parasitoid communities. Even within the uniform focal habitat type (heathland dominated by mountain avens), the abundances of species and the strengths interspecific interactions changed with climatic factors. As parasitoids are fairly specialized predators, they are particularly sensitive to environmental changes.

"To understand the more general impact of climate, we cannot always go species-by-species in each area. Rather, we need to uncover the uniting characteristics of species which show similar responses to climatic conditions," explains Kankaanpaa.

For the parasitoid insects of the North, one key trait turned out to be the way in which parasitoid species use their hosts. Species that spend considerable time dormant inside of their host, waiting for it to grow, form one group: they tend to prefer sites on which snow melts early and summers which are hot and dry. Conversely, species that attack full-sized host larvae or pupae appear to do better at sites where thicker snow cover offers protection from cold winter temperatures.

The larvae of the dominant avens-feeding moth species also preferred warm and dry areas in the landscape. The same association was evident in a long time-series collected as a part of an ongoing monitoring program at the Zackenberg research station. During the past two decades, winters with thin snow cover and warm summers have resulted in an increased proportion of avens flowers being consumed.

WHAT HAPPENS WHEN SEASONALITY OF SPECIES SHIFTS?

A potentially serious consequence of climate change is a phenological mismatch - i.e. a situation in which the seasonality of interacting species change at a different rate. This can lead to situations where e.g. herbivorous insects escape some of their predators in time, thereby allowing herbivore populations to grow. The researchers found that the two dominant parasitoids preying on the focal moth larvae showed distinctly different temporal relationships with their host. One of the parasitoids matched the flowering of mountain avens and the development of its host larvae near perfectly across the wide range of spring arrival recorded within the study area. Yet, the other parasitoid species proved only loosely trimmed to coincide with specific life stages of its host. Such shifts can make a big difference once two parasitoids occupy the same host individual and competition within the still-living food source becomes physical. If one is then at the right stage and the other not, this can affect the outcome of the game.

"The parasitoids communities of the far North have previously received little attention. This is surprising, as these communities are species-poor, and thereby offer excellent opportunities to study what factors influence how species come together and interact," says Kankaanpaa.

The research group behind the study bridges two countries and two universities, the University of Helsinki and the Swedish University of Agricultural Sciences (SLU). It is led by Professor Tomas Roslin. The group has studied insect interactions across the world and in Greenland and regards the Arctic as an ideal observatory for monitoring the effects of climate change. In the High Arctic, the climate is changing especially fast - and within this zone, North East Greenland offers a region where other human impacts are minimal, thereby allowing researchers to isolate the unique effects of climate.

How insect communities vary along landscape-level micro-climates provides clues as to how such communities may change with time. Kankaanpää stresses that there is much work to be done before we can fully understand how climate change will reverberate through networks of live interactions. Do, for example, the outbreaks of a single herbivore species pose direct risks to those other herbivores with which it happens to share parasitoids? Can the feeding of large hoards of the joint enemies eventually extirpate the rarer host?

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CCNY's David Lohman finds Asian butterfly mimics different species as defense mechanism

CITY COLLEGE OF NEW YORK

Research News

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IMAGE: PHOTO OF BUTTERFLY IN THE WILD, ELYMNIAS HYPERMNESTRA BEATRICE. view more 

CREDIT: PHOTO CREDIT: GAN CHEONG WEEI.

Many animal and insect species use Batesian mimicry - mimicking a poisonous species - as a defense against predators. The common palmfly, Elymnias hypermnestra (a species of satyrine butterfly), which is found throughout wide areas of tropical and subtropical Asia, adds a twist to this evolutionary strategy: the females evolved two distinct forms, either orange or dark brown, imitating two separate poisonous model species, Danaus or Euploea. The males are uniformly brown. A population group is either entirely brown (both males and females) or mixed (brown males and orange females).

City College of New York entomologist David Lohman and his collaborators studied the genome of 45 samples representing 18 subspecies across Asia to determine their evolutionary history and to establish what genes were responsible for the color variation in females. They found that neither the orange nor brown females had a common recent ancestor.

"The conventional wisdom is that once something evolves and you lose it, it's hard to re-evolve it," said Lohman. "That suggests something is acting like a switch, switching the gene on or off."

The researchers found two DNA nucleotides on the Elymnias hypermnestra genome that regulate WntA, a gene associated with color patterning in butterfly species.

The WntA gene can be switched on to recreate the phenotypic shift, even where it hasn't appeared for several generations. Reaching back into genetic history allows a species to create a variant without having to re-evolve the intermediate biochemical pathways.

"Evolution of a phenotype can be more plastic than we thought," said Shen-Horn Yen, one of Lohman's collaborators from the Department of Biological Sciences, National Sun Yat-Sen University, Taiwan.

The study appears in the journal Proceedings of the Royal Society B.

To Lohman, studying Elymnias hypermnestra encapsulates the study of biodiversity in its entirety. There's a universe of variety in color, form and size and genetic variability all found in a single genus of butterfly.

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