Earth Is Using 173% of The World's Total 'Biocapacity', Scientists Warn


(Monty Rakusen/Getty Images)

CARLY CASSELLA
27 APRIL 2021

Humans around the world are consuming far more natural resources than our planet can continue to sustain, condemning the majority of people to ecological poverty, according to new research.

When researchers tried to put a number on our natural resource deficit for the year 2017, they found our global population of over 7.5 billion people had spent 173 percent of the world's total biocapacity that year.

This is obviously a major overshoot, and it's part of a trend that has gotten much worse in recent decades. In 1980, humanity was using only 119 percent of the world's biocapacity.

Much of the surge in demand since then has been driven by wealthier nations, requiring higher and higher standards of living, even if they have to buy resources from elsewhere.

Today, nearly three quarters of all people live in nations with lower-than-average incomes and a scarcity of natural resources, which means they simply can't compete.

Clearly, the path we are on today cannot be trod forever. If the world is truly serious about eradicating poverty, then experts say we cannot keep ignoring the limiting factor that is Earth's resources.

Dividing the world's countries into four categories, based on their gross domestic product (GDP) per capita and their local ecological deficit, researchers have illustrated an unsustainable shift in humanity's demand for resources.


If we don't seek to rapidly improve resource security - through conservation and restoration, fossil fuels cuts, sustainable development, and shifting consumption patterns - the authors argue our natural capital will be unable to recover, and our hope for a more equal future will be wholly undermined.

In the year 1980, 57 percent of the global population lived in a country with the "double curse" of a below-average income and a deficit in biological resources, the researchers found. In 2017, that number had jumped to 72 percent.

On the other hand, higher income countries with resource deficits make up only 14 percent of the world population, but this minority demands an astonishing 52 percent of the planet's biocapacity.

Switzerland and Singapore are two notable nations that fall into this latter category, which means they are shielded from resource insecurity because they have the money to buy what they need from other places.

To live in a truly sustainable way, scientists think we should be using no more than half our planet's resource capacity, but if everyone in the world lived like those in higher income, low resource countries, like Switzerland, we would need roughly 3.67 planet Earths to meet global demand.

"If the development patterns of these cities or territories are not replicable, there is only one way for such entities to avoid their own demise: they must be certain that they can financially outcompete everybody else on this planet forever to secure their resource metabolism," the authors conclude.

"Requiring such a strategy to succeed is precarious for regions at any income level."

But it's especially dangerous for lower income regions, who cannot compete for resources at the same level. Without assistance from wealthier nations, there's really not a lot these nations can do.

In fact, researchers argue lower income countries currently face a catch-22. Continuing with the status quo will no doubt make their current resource crisis worse, but making rapid changes to human resource consumption will also cost a lot of money, which many simply cannot afford.

What's more, because wealthier nations consume many more resources than are absolutely necessary to live, they have much more wiggle room in the face of future disaster.

In an economic downturn, for instance, a loss of resources isn't as catastrophic for Spain as it would be for Niger or Kenya, where such a rapid loss could erode food and energy security for many more people, putting their very lives at risk.

"This paper strengthens the case that biological resource security is a far more influential factor contributing to lasting development success than most economic development theories and practices would suggest," the authors conclude, "and shows how unevenly it affects distinct human populations."

Clearly, we are spending more than humanity or our planet can afford.

The study was published in Nature Sustainability.

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2 Simple Charts Show When You Don't Need to Wear a Mask Under New CDC Guidelines

HILARY BRUECK, BUSINESS INSIDER
28 APRIL 2021

The Centers for Disease Control and Prevention wants people to know there are clear, personal benefits to getting vaccinated.

On Tuesday, the agency released new guidelines for when fully vaccinated people – that is, those who've allowed their shot(s) two full weeks to take effect – can take off their masks.


"We all miss the things that we used to do before the pandemic," CDC Director Rochelle Walensky said, announcing the new guidance.

"If you are fully vaccinated and want to attend a small outdoor gathering with people who are vaccinated and unvaccinated, or dine at an outdoor restaurant with friends from multiple households, the science shows – if you're vaccinated – you can do so safely, unmasked."

The chart below, from the CDC, shows which activities the agency considers safe to do unmasked outside.

You'll note that fully vaccinated people can do almost anything outdoors without a mask, with the notable exception of attending a crowded event, like a parade, game, or concert.

(Centers for Disease Control and Prevention)

The CDC is loosening the reins a little bit for unvaccinated folks as well – suggesting it's OK to go outside without a mask on, as long as you're just:
Venturing out for some exercise with members of your own household (and not coming into close physical contact with others while you're walking, biking, or running).
Or, going to a small outdoor gathering with fully vaccinated friends or family.


In all other cases, the CDC still stresses that masks should be worn, especially when people are indoors.

During the briefing, Walensky reiterated that the science is clear now that the risks of catching the coronavirus are much lower outdoors, where there's near infinite ventilation, than inside.

"There's almost a 20-fold increased risk of transmission in the indoor setting," she said.

"That, coupled with the fact that we now have 37 percent of people over the age of 18 fully vaccinated, and the fact that our case rates are now starting to come down, motivated our change in guidance."

Indoors, in public spaces, the CDC still says everyone should wear masks.

The chart below, with vaccinated people in green, and unvaccinated in yellow and red, is meant to demonstrate the relative risks of doing activities indoors during the pandemic, even with a mask on.

You'll note that singing, exercising, and eating indoors, all activities where people may potentially be emitting more infectious viral particles into the air, are considered less safe for unvaccinated people than vaccinated. The chart below has unvaccinated people on the left, and vaccinated on the right:

  

(Centers for Disease Control and Prevention)

This article was originally published by Business Insider.

A Massive Study of Nearly Every Glacier on Earth Just Revealed a Devastating Trend


Chapman glacier in Canada. (NASA/METI/AIST/Japan Space Systems, and US/Japan 

NICOLETTA LANESE, LIVE SCIENCE
29 APRIL 2021


Earth's glaciers are shrinking, and in the past 20 years, the rate of shrinkage has steadily sped up, according to a new study of nearly every glacier on the planet.

Glaciers mostly lose mass through ice melt, but they also shrink due to other processes, such as sublimation, where water evaporates directly from the ice, and calving, where large chunks of ice break off the edge of a glacier, according to the National Oceanic and Atmospheric Administration (NOAA).


By tracking how quickly glaciers are shrinking, scientists can better predict how quickly sea levels may rise, particularly as climate change drives up average global temperatures.

But estimating the rate of glacier shrinkage can be notoriously difficult; past estimates relied on field studies of only a few hundred glaciers out of the more than 200,000 on Earth, as well as sparse satellite data with limited resolution, the authors noted in their new study, published Wednesday (April 28) in the journal Nature.

Some of this satellite data captured changes in surface elevation, but only sampled a few places and at sparse time points.

Other satellites detected slight shifts in the Earth's gravitational field, but could not disentangle how much glacier shrinkage contributed to these shifts, as opposed to mass changes in ice sheets or solid earth, for instance.

Related: Time-lapse images of retreating glaciers

To zero in on a more precise estimate, the team used myriad satellite and aerial images to survey 217,175 glaciers, accounting for nearly all of Earth's glaciers.

In particular, a 20-year archive of images from NASA's Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER), a high-resolution sensor aboard the Terra satellite, supplied the team with a wealth of data and allowed them to make more certain estimates of glacier mass loss through time.


"We not only have the complete spatial coverage of all glaciers, but also repeat temporal sampling," meaning measurements taken from many points in time, said first author Romain Hugonnet, a doctoral student at the University of Toulouse in France and the Laboratory of Hydraulics, Hydrology and Glaciology (VAW) at ETH Zürich in Switzerland.

The team found that, between 2000 and 2019, glaciers collectively lost an average of 293.7 billion tons (267 billion metric tonnes) of mass per year, give or take 17.6 billion tons (16 billion metric tonnes); this accounts for about 21 percent of the observed sea-level rise in that time frame, the authors noted.

Regional and global mass change rates with time series of mean surface elevation change rates for glaciers. (Hugonnet et al., Nature, 2021.)

And for each decade since 2000, the overall rate of glacier mass loss has been accelerating, increasing by about 52.8 billion tons (48 billion metric tonnes) per year, which may account for an observed acceleration in sea-level rise.

These estimates significantly narrow the uncertainty around how much mass glaciers lost in recent decades, Hugonnet said.

For instance, the latest report from the Intergovernmental Panel on Climate Change (IPCC) and a recent global study, published in 2019 in the journal Nature, both calculated mass loss estimates in the same ballpark as the new study; but their margins of error spanned several hundred gigatonnes on either side.


Hugonnet and his team were able to greatly reduce this uncertainty by using the ASTER data.

ASTER captures images on the visible and near-infrared spectrum, "so almost what we see with our own eyes," Hugonnet said.

Because the sensor orbits Earth about 438 miles (750 kilometers) above the planet's surface, it can snap images of the same locations from multiple angles: once as it passes directly over a spot and once as if it's "looking back" from where it came.

The two snapshots can then be used to reconstruct the 3D topography of Earth's surface, and in this case, the 3D structure of glaciers across the planet. Hugonnet and his team quantified these changes in volume and then multiplied that by the density of glacier ice, to determine how much mass the glaciers had lost.

The group also double-checked their work against data from NASA's Ice, Cloud, and land Elevation Satellite (ICESat) and Operation IceBridge campaigns, a NASA project in which a fleet of research aircraft surveys Earth's polar ice.

This additional data confirmed that the ASTER images generally matched up with other available data front the same time period, and it also helped the team correct for statistical "noise" in the ASTER data.


Using these methods, the team calculated a fairly confident estimate, but some uncertainty still remains, Hugonnet said.

"The problem with glaciers is that we're not only losing ice, we're also losing firn," a kind of partially compacted snow usually found on top of glaciers, he said. The current study didn't differentiate firn from ice when estimating mass loss, "so it's, right now, our largest source of uncertainty," in terms of nailing down a precise rate, Hugonnet said.

In addition, the team noted that not all Earth's glaciers lost mass at the same rates. "What was even more interesting, and a bit surprising, was to see that some regions decelerated and others accelerated," Hugonnet said.

For instance, mass loss from glaciers in Alaska and western Canada ramped up significantly in the study time frame, while loss from Icelandic, Scandinavian and southeast Greenland glaciers slowed between the early 2000s and late 2010s.

Zooming in on these regions, the authors found that regional climate conditions, specifically long-term fluctuations in precipitation and temperature, helped explain these stark differences.

So while Iceland, Scandinavia and Greenland entered a decade of relatively cool, wet conditions in the second decade of the 21st century, northwestern North America entered a relatively dry period, meaning glaciers ultimately lost more ice than they gained snow.

"We have those fluctuations that exist in some regions and can last for about a decade, sometimes," Hugonnet said.

"This is also why we need such globally complete sets of observations, such as the one we provided," he noted.

Tracking average glacier mass loss, on a global scale, can help scientists predict global sea-level rise; but on a local scale, glacier mass loss can drastically alter nearby bodies of water and the availability of water resources, as well as threaten to trigger disasters, such as avalanches and devastating spring floods, Hugonnet said.

So it's important to capture both the big picture and fine details.

Related content:

Images of melt: Earth's vanishing ice

Photo gallery: Antarctica's Pine Island Glacier cracks

In photos: Huge icebergs break off Antarctica

This article was originally published by Live Science. Read the original article here.

A Curious Hadrosaur With Super-Weird Teeth Has Been Unearthed in Japan

Artist’s illustration of Y. izanagii (center) with other hadrosaurs. (Masato Hattori)

DAVID NIELD
29 APRIL 2021

Meet Yamatosaurus izanagii, a new genus and species of hadrosaur (or duck-billed dinosaur) discovered on a small island off the southern coast of Japan in 2004, and now identified in a new study.

As well as expanding the dinosaur family tree, the fossil find is going to be useful for experts trying to track the migration patterns of hadrosaurs.

While early members of the hadrosaur family most likely wandered across the Bering Land Bridge from Asia to North America, the migration could have become a two-way street, with some later clades returning.

This has given rise to questions over the origins of some later day hadrosaur genera found in places like Japan. Now, features of the partial skeleton and its estimated date – 71-72 million years ago, just before dinosaurs became extinct – tip the scales in favor of these late-blooming branches of the hadrosaur tree also starting in Asia, instead of in the other direction.

The new species follows the 2019 discovery by the same team of another hadrosaurid called Kamuysaurus, found on the northern Japanese island of Hokkaido.

"These are the first dinosaurs discovered in Japan from the late Cretaceous period," says paleontologist Yoshitsugu Kobayashi, from Hokkaido University Museum in Japan. "Until now, we had no idea what dinosaurs lived in Japan at the end of the dinosaur age."


"The discovery of these Japanese dinosaurs will help us to fill a piece of our bigger vision of how dinosaurs migrated between these two continents."

Part of the reason for the abundance and diversity of hadrosaurs was their chewing ability: the animals had hundreds of tightly packed teeth in their mouths, which were replaced from below as they wore down and fell out.

And it's the dental structure that makes Y. izanagii unique: the number and development of the teeth differs noticeably, and it probably evolved to feed on different types of vegetation to other hadrosaurs.

The right dentary of Y. izanagii distinguishes it from other known hadrosaurs. (SMU)

The researchers also noticed an unexpected level of development in the shoulder and forelimbs, marking an evolutionary step in the species from a bipedal to a quadrupedal dinosaur which could change how we interpret their evolution. It's another interesting variation in a dinosaur that dominated the Cretaceous period.

"In the far north, where much of our our work occurs, hadrosaurs are known as the caribou of the Cretaceous," says paleontologist Anthony Fiorillo, from Southern Methodist University in Texas.


The team behind the new study suggests that hadrosaurs could have crossed from Asia to present-day Alaska via the Bering land bridge, and then spread across almost the whole of North America. Japan was attached to Asia until around 15 million years ago.

And if you're wondering about the name, Yamato is the ancient name for Japan, while Izanagi is a god in Japanese mythology believed to have created the Japanese islands – starting with Awaji Island, where the new Yamatosaurus was found.

There's one more important point to take from the discovery and identification of Y. izanagii: the importance of teamwork. The original bones were uncovered by an amateur fossil hunter in a cement quarry.

"Japan is mostly covered with vegetation with few outcrops for fossil-hunting," says Kobayashi. "The help of amateur fossil-hunters has been very important."

The research has been published in Scientific Reports.

THE HADROSAUR IS ALBERTA'S OFFICIAL DINOSAUR

Extreme Poverty Will Be Reduced if We Tackle Climate Change Right, Study Shows


(Gaston Roulstone/Unsplash)

PATRICK GALEY, AFP
28 APRIL 2021

Ambitious climate policies could reduce extreme poverty in developing countries if governments opted for robust taxes on emitters that were then fairly distributed to help the poor, new research showed Tuesday.


Authors of the study said the results showed that policymakers were facing a false choice between climate change mitigation and poverty reduction.

Since fossil fuels and agricultural chemicals such as fertilizers are so heavily subsidized, any attempt to remove taxpayer support to these unsustainable practices frequently prompts fears of higher prices for consumers.

Industry lobbyists also argue that cheap sources of energy such as coal have a role to play in expanding access to electricity in developing countries.

Researchers at the Potsdam Institute for Climate Impact Research (PIK) used computer models to predict how levels of global poverty might be affected by various interventions aimed at limiting global warming.

They found that the world was on course to have around 350 million people living in extreme policy - i.e. on less than US$1.90 a day - by 2030, far short of the UN goal to eradicate extreme poverty by the end of the decade.

The authors noted that this figure did not factor in the economic disruption caused by the pandemic, or the adverse effects of climate change.


They then modeled in ambitious climate policies consistent with the 1.5 °C temperature goal of the Paris Agreement, and found that this could increase the number of people living in extreme poverty by an additional 50 million.

But when they modeled in equitable redistribution of national carbon price revenues - which would see poorer, and therefore lower-polluting sections of society receive money accrued from richer polluters - they found that this could compensate for the other effects of climate mitigation.

They even found it could slightly reduce the number of people living in poverty - about 6 million fewer by 2030.

"Climate policies safeguard people from climate change impacts like extreme weather risks or crop failure," said Bjoern Soergel, a PIK researcher and lead author of the study, published in Nature Communications.

"Yet they can also imply increased energy and food prices. This could result in an additional burden especially from the global poor, who are already more vulnerable to climate impacts."
'Climate dividend'

Soergel said that governments could combine emissions prices with international redistribution of the revenues they generated - a sort of "climate dividend".

"The revenues are returned equally to all citizens, which turns poorer households with typically lower emissions into net beneficiaries," he said.


The authors suggested a scheme of international climate finance transfers from high-income to low-income countries to offset the additional burden poorer nations face in seeking to limit climate change.

Just 5 percent of emission pricing revenues from industrialized nations would be enough to more than compensate for the policy side effects of climate mitigation in Sub-Saharan Africa, according to the study.

"Combining the national redistribution of emission pricing revenues with international financial transfers could thus provide an important entry point towards a fair and just climate policy in developing countries," said co-author Elmar Kriegler.

© Agence France-Presse

Serial Collapses of Ancient Pueblo Societies Carry a Stark Warning For Today's World

Puebloans Cliff Palace, Mesa Verde, Colorado. (Daniela Duncan)


TESSA KOUMOUNDOUROS
28 APRIL 2021

In the area where the Colorado, Utah, Arizona and New Mexican borders now meet, ancestral Pueblo societies thrived and then collapsed several times, over the span of 800 years.

Each time they recovered, their culture transformed. This shifting history can be seen in their pottery and the incredible stone and earth dwellings they created. During 300 of those years, some Pueblo peoples, who also used ink tattoos, were ruled by a matrilineal dynasty.

As in the collapse of other ancient civilizations, ancestral Pueblo social collapses align with periods of changing climate - but Pueblo farmers often persevered through droughts, suggesting that there was more to their collapses than just environmental conditions.

So archaeologists took a closer look at what was happening in these societies, before 1400 CE, leading up to their times of upheaval. Using tree-ring analyses of wood beams for building construction allowed the researchers to construct a time series of the Pueblo societies' productivity.

Peak construction periods were clustered around good maize growing seasons, even though these times, on average, were not climatically better for growing maize than when there was a lull in said construction.

The new research found that while the societies often bounced back fairly quickly after construction lulled, there were distinct slow-downs in recoverythat coincided with increased signs of violent.

This sort of system slowdown can be seen in other regional collapses of ancient societies like the Neolithic Europeans, that had no link to changing climates. It's also a feature of complex systems as diverse as the tropical rainforest and the human brain.

"Those warning signals turn out to be strikingly universal," said Wageningen University complexity scientist Marten Scheffer. "They are based on the fact that slowing down of recovery from small perturbations signals loss of resilience."

Scheffer and colleagues suspect slowly accumulating social tensions - like wealth inequality, racial injustice, and general unrest - wore away at social cohesion until all it took was a bit more pressure from another drought to tip them over the edge. This appears to have happened to the Pueblo peoples around 700, 900, and 1140 CE.

However, during the late 1200s, a combination of drought and external conflict spurred the ancestral Pueblo peoples to permanently leave the region.

"Societies that are cohesive can often find ways to overcome climate challenges," explained Washington State University archaeologist Tim Kohler.

"But societies that are riven by internal social dynamics of any sort – which could be wealth differences, racial disparities or other divisions – are fragile because of those factors. Then climate challenges can easily become very serious."

The ancient Pueblo peoples did find a way to thrive elsewhere, possibly by dramatically transforming their culture once more, and today their descendants live on tribal lands surrounding the empty places that were once the center of the Pueblo world. Their history provides us with a significant warning.

"Today we face multiple social problems including rising wealth inequality along with deep political and racial divisions, just as climate change is no longer theoretical," Kohler said. "If we're not ready to face the challenges of changing climate as a cohesive society, there will be real trouble."

If we want to avoid repeating history, we'd better pay attention.

Their research was published in PNAS (link not yet live at time of writing)

This Weird 'Horned' Crocodile Could Represent a New Branch on The Tree of Life

CLARE WATSON
28 APRIL 2021


An extinct 'horned' crocodile that once called Madagascar home has finally found its place on the tree of life, according to a new study of two skulls stored at the American Museum of Natural History.

Based on ancient DNA extracted from the museum specimens, researchers have posited that the horned crocodile was closely related to modern-day 'true' crocodiles which live throughout the tropics, but it sits on an adjacent branch of the crocodile family tree that split some 25 million years ago.

This rejigs scientific thinking about the horned crocodile's evolutionary relationships, which most recently had them pegged as relatives of dwarf crocodiles.

The study also suggests that the ancestor of modern crocodiles likely originated in Africa, and goes some way towards settling the long-standing controversy that has swirled about the horned crocodile's evolutionary history.

Voay robustus skull from southwestern Madagascar. (M. Ellison/©AMNH)

Heavy-built horned crocodiles, named for unusual bony protrusions atop their heads and known today as Voay robustus, roamed Madagascar alongside another, more slender crocodile, according to accounts from early explorers.

But while the Nile crocodile (Crocodylus niloticus) still inhabits the island to this day, and is the largest and most common crocodilian in all of Africa, horned crocodiles went extinct after humans arrived on Madagascar's shores, as early as 9,000 years ago.


"They blinked out just before we had the modern genomic tools available to make sense of the relationships of living things," said study author Evon Hekkala, a behavioral ecologist turned conservation geneticist at Fordham University in New York.

"And yet, they were the key to understanding the story of all the crocodiles alive today."

Understandably, horned crocodiles have been the focus of some intense study and debate amongst paleontologists. But after 150 years of investigations, researchers haven't been able to agree on where to place Madagascar's horned crocodile on the tree of life.

At first, horned crocodiles were described as a new species of "true crocodile" alongside the Nile crocodile. But then scientists thought they had more in common with shorter, smaller dwarf crocodiles.

An extinct crocodile skull analyzed for its DNA in the study. (M. Ellison/©AMNH)

Part of the problem is crocodiles are unusual beasts that look remarkably similar to their fossilized ancestors who lived some 200 million years ago. These physical similarities make teasing out the relationships between modern crocodiles and their ancient ancestors difficult.

"We've been trying to get to the bottom of the great diversity that exists among them," said Hekkala, who appears to have a knack for solving crocodilian mysteries using ancient DNA.


In 2011, as a graduate student, she discovered by genetic analysis that the Nile crocodile was actually two distinct species, not one – and the species differed by two whole chromosomes.

This time around, Hekkala and her colleagues mapped mitochondrial DNA extracted from the teeth of two V. robustus specimens and compared them against a few crocodilian reference genomes.

The horned crocodile skulls, which date back to around 1,300 to 1,400 years old, were collected on an expedition to southwest Madagascar between 1927 to 1930, and have been stored at the American Museum of Natural History ever since.

Mitochondrial DNA, which is passed from mother to offspring, tends to stay much the same over generations, making it a useful tool for tracing evolution through maternal ancestry. But as ancient DNA fragments with age, it always depends on how well the DNA of a particular specimen has been preserved.

The genetic comparisons here suggested that the horned crocodile represents a "sister lineage" to 'true' crocodiles, placing V. robustus right next to modern-day Crocodylus, such as Australia's saltwater crocodile, on the evolutionary tree.

It was only with modern DNA techniques and the right computational setup that the research team could "actually fish out this DNA from the fossil and finally find a home for this species," explained study author and geneticist George Amato from the American Museum of Natural History's Institute for Comparative Genomics.

So, you could say this is a long-awaited homecoming for V. robustus.

"This finding was surprising and also very informative to how we think about the origin of the true crocodiles found around the tropics today," Amato added.

"The placement of this individual suggests that true crocodiles originated in Africa, and from there, some went to Asia and some went to the Caribbean and the New World. We really needed the DNA to get the correct answer to this question."

The research was published in Communications Biology.

Scientists Discover Psychedelic-Like Drug That Doesn't Cause Hallucinations

THAT'S NO FUN

(Victor de Schwanberg/Getty Images)


CARLY CASSELLA
29 APRIL 2021

Scientists have discovered a psychedelic-like drug that can produce rapid, long-lasting antidepressant effects in mice without the effect of hallucinations.

The molecule, called AAZ-A-154, acts on the same serotonin receptors in the brain as antipsychotic drugs (like clozapine) and psychedelics (like LSD), promoting neuronal growth and producing beneficial behaviors in rodents for weeks after a single dose.

Researchers say the treatment is comparable to the fast-acting nature of ketamine, which has recently emerged as a promising drug for conditions like depression, substance abuse, and post-traumatic stress disorder.

However, some psychedelic drugs that are being investigated for their medical effects, such as psilocybin, routinely trigger hallucinations, which means they should only really be used as a treatment under the guidance and supervision of experts.

Finding a safe alternative without the risk of hallucinations would be extremely useful clinically, but the thing is, we still don't know if these hallucinogenic effects are needed to actually reshape the brain.

To explore this issue in greater detail, researchers from the University of California, Davis (UC Davis) genetically encoded a green fluorescent protein into a specific type of serotonin receptor responsible for triggering hallucinations, allowing them to observe the receptors being activated in living tissue.

Applying the novel sensor to 34 compounds with extremely similar structures but unknown hallucinogenic potentials, the team found one molecule in particular, AAZ-A-154, which exhibited a high selectivity for the receptor with few side effects.


When this compound was administered to mice, it produced antidepressant-like effects within 30 minutes and failed to cause any head-twitches, an indicator in mice suggesting the compound would cause hallucinations in humans. Even at relatively high doses, the results appeared to be the same, with cognitive benefits lasting for over a week.

According to the researchers, this is only the second non-hallucinogenic drug they've found that shows clinical benefits similar to psychedelics.

The other compound, Tabernanthalog (TBG), was engineered last year by some of the same authors, and while it increased the branching of mouse neurons in similar ways to ketamine, LSD, MDMA, and DMT, it appears AAZ-A-154 may have stronger and more sustained antidepressant effects in live animals.

Compared to existing psychedelics, a drug that people can take home, put in their medicine cabinets, and take on their own without supervision would be a much safer and more practical alternative, and TBG and AAZ-A-154 seem like promising new candidates.

So far, these compounds have only been tested in mice, so we still don't really know how they differ functionally to other psychedelic substances humans take with similar structures.


Far more research is needed to understand the underlying mechanisms, both at the molecular and cellular level, before we can even consider testing these compounds on our own species.

"Serotonin reuptake inhibitors have long been used for treating depression, but we don't know much about their mechanism," says UC Davis biomedical researcher Lin Tian.

"It's like a black box."

Now we just need to crack the lid and see what's underneath.

The study was published in Cell

Even Closed Oil Wells Are Still Spewing Methane Into The Air, Scientists Warn

(Cavan Images/Getty Images)


PETER DOCKRILL
29 APRIL 2021


The legacy of abandoned oil wells in the US isn't hard to see, even leaving gaping holes in the landscape that are frightening to look at. But their invisible aftermath is more alarming still.


Across the US and Canada, there are millions of abandoned or inactive oil and gas wells left behind by their former operators, and often improperly sealed. These stranded reserves – sometimes called orphan wells – may have been deserted by humans, but they are not a spent force.

Abandoned wells, hundreds of thousands of which are thought to be undocumented, are estimated to spew vast amounts of heat-trapping methane emissions into the atmosphere, far exceeding the projections of environmental authorities such as the US EPA.

Conservative estimates suggest abandoned wells might represent up to 4 percent of methane gas emissions from oil and gas systems in the US, although the veracity of such estimates is debatable, given the relative lack of on-the-ground measurements.

It gets worse – in part due to the fractured nature of abandonment. Aside from outright abandoned wells, a sub-category of inactive wells known as 'shut-ins' can pose the same methane-leaking risks, but fly under the radar in official figures.

Shut-ins are idle wells that are not currently being used for oil production, likely due to market conditions, but which could be re-activated in the future. Despite all the growing concern over just how big the abandoned wells fiasco is, shut-ins, many of which are uncapped, have never been measured for their own contribution to greenhouse gas emissions.


In a new study by scientists at the University of Cincinnati, researchers sought to rectify that.

Biogeochemist Amy Townsend-Small and her research assistant Jacob Hoschouer visited the sites of 37 inactive wells located on private property in Texas's Permian Basin, the largest oil production basin in the US, which on the whole produces roughly 60 percent higher methane emissions than the national average for oil and gas production regions.

Part of the problem, the researchers found, is shut-ins. While many of the inactive wells measured for elevated methane levels showed either no leaks or little leaking, several were leaking methane in high amounts, up to a maximum of 132 grams per hour.

"Some of them were leaking a lot," Townsend-Small says. "A few sources are responsible for most of the leaks."

While the problem may vary from shut-in to shut-in, the high readings of the outliers pushed the average for all the inactive wells measured to 6.2 grams per hour – which is higher than the average output for abandoned wells in other western states (including Colorado, Utah, and Wyoming) but lower than counterparts in the Appalachian Basin in the US northeast.


If the same levels of leaking were found for all of Texas's roughly 100,000 wells, it would be about 5.5 million kilograms of methane released annually – around the equivalent of burning 150 million pounds of coal each year, the researchers say.

Again, though, we can't yet conclude too much from the existing data, since there are millions of abandoned or inactive wells in North America, and many more measurements need to be taken.

Once we do, however – if similar patterns of leaking bear out across all sites – there could be practical solutions to fixing most of the leaks by focusing on the worst offenders.

"If you want to make a big impact, you only have to fix the big leakers," Townsend-Small told Grist and the Texas Observer.

Overall, inactive wells seem to produce less methane emissions than active oil-producing wells, but these largely neglected and unmaintained sites also present other environmental problems.

In their expedition, Townsend-Small and Hoschouer observed evidence of polluted water pooling at five of the wells, with brine leaks producing ponds surrounded by dead vegetation and a strong gassy smell.


"I was horrified by that," Townsend-Small says.

"I've never seen anything like that here in Ohio. One was gushing out so much water that people who lived there called it a lake, but it's toxic. It has dead trees all around it and smells like hydrogen sulfide."

Ultimately, there's a lot more work to do, both in assessing the environmental and health impacts of what these tapped but unspent wells could represent to the planet and its people.

The Biden administration has already strongly signaled an intention to begin addressing the toxic legacy of abandoned wells, encompassed in a US$16 billion spending plan.

In addition to plugging the worst leakers and conducting more measurements at inactive wells, the researchers say regular inspections of shut-ins could help prevent neglected sites from becoming problematic emitters, and infrared cameras could be set up to identify leaks.

Ideally, of course, all of this would have been done yesterday. While carbon dioxide reductions have been the central focus of many climate initiatives, the unfortunate truth is that in the shorter term, methane is a far more potent greenhouse gas – with a warming potential 28 times greater over a 100-year period.

Despite the severe dangers, emissions are entirely headed the wrong way. Just this month, a new analysis by the NOAA showed annual global methane emissions just experienced their largest year-on-year increase since records began in 1983.

Old wells aren't the only things that are broken.

The findings are reported in Environmental Research Letters.

A Pregnant Ancient Egyptian Mummy Has Been Discovered in a Shocking World First


Photo and scans of the mummy. (Ejsmond et al., J. Archaeol. Sci., 2021)



MICHELLE STARR
30 APRIL 2021


At first, archaeologists thought they were scanning the mummy of an ancient Egyptian priest named Hor-Djehuty. Then, in the body's abdomen, images revealed what appeared to be the bones of a tiny foot.


Full scans confirmed it: the foot belonged to a tiny fetus, still in the womb of its deceased and mummified mother.

Not only is this the first time a deliberately mummified pregnant woman has been found, it presents a fascinating mystery. Who was the woman? And why was she mummified with her fetus? So peculiar is the discovery, scientists have named her the Mysterious Lady of the National Museum in Warsaw.

"For unknown reasons, the fetus had not been removed from the abdomen during the mummification," archaeologist Wojciech Ejsmond of the Polish Academy of Sciences told Science in Poland.

"For this reason, the mummy is really unique. Our mummy is the only one identified so far in the world with a fetus in the womb."

The mummy and its sarcophagus were donated to the University of Warsaw in 1826 and kept in the National Museum in Warsaw, Poland since 1917. The artifact actually has an interesting history. The mummy was initially thought to be female, likely because of the elaborate sarcophagus.

The coffin, cartonnage case, and mummy. (National Museum in Warsaw, Warsaw Mummy Project)

It wasn't until around 1920 when the name on the coffin and cartonnage was translated that perception shifted. The writing revealed that the interred was named Hor-Djehuty, and was highly placed.

"Scribe, priest of Horus-Thoth worshiped as a visiting deity in the Mount of Djeme, royal governor of the town of Petmiten, Hor-Djehuty, justified by voice, son of Padiamonemipet and lady of a house Tanetmin," the translation read.


In 2016, however, computer tomography revealed that the mummy in the sarcophagus may not have actually been Hor-Djehuty. The bones were too delicate, male reproductive organs were missing, and a three-dimensional reconstruction revealed breasts.

Given that artifacts weren't exactly handled with the best care in the 19th century, and given that the coffin and cartonnage were indeed made for a male mummy, it seems that an entirely different mummy was placed in the sarcophagus at some point - perhaps to be passed off as a more valuable artifact.

This is supported by damage to some of the mummy's bandages - likely caused by 19th century looters rifling through looking for amulets, the researchers said.

Thus, it's impossible to know who exactly the woman was, or even if she came from Thebes where the coffin was found; however, a few facts can be gauged from her remains.

Firstly, she was mummified with great care, and with a rich set of amulets, suggesting in and of itself that she was someone important - mummification was a luxury in ancient Egypt, unavailable to most.

X-ray and CT scans of the mummy's abdomen, revealing the fetus. (Ejsmond et al., J. Archaeol. Sci., 2021)

She died just over 2,000 years ago, in approximately the first century BCE, between the ages of 20 and 30, and the development of the fetus suggests she was between 26 and 30 weeks pregnant.

As the first-ever discovery of a pregnant embalmed mummy, the Mysterious Lady poses fascinating questions about ancient Egyptian spiritual beliefs, the researchers said. Did the ancient Egyptians believe that unborn fetuses could go on to the afterlife, or was this mummy a strange anomaly?

It's unclear how she died, but the team believes that analysis of the mummy's preserved soft tissues might yield some clues.

"High mortality during pregnancy and childbirth in those times is not a secret," Ejsmond said. "Therefore, we believe that pregnancy could somehow contribute to the death of the young woman."

The team's research has been published in the Journal of Archaeological Science.