US Gallup Poll: Big majorities back range of climate change policies


Solid majorities of Americans backed providing tax credits for the installation of solar power and other types of clean energy systems in homes.

 File Photo by John Angelillo/UPI | License Photo

April 11 (UPI) -- Americans decisively support a series of six policy proposals to fight climate change backed by the Biden administration, according to a Gallup Poll released Monday.

The poll results showed that by varying degrees, solid majorities of U.S. residents back such climate proposals as providing tax credits for installing home clean energy systems to spending federal money on constructing electric vehicle charging stations.

At the high end of the scale, 89% of respondents favored the clean energy tax credit idea, while the least favorable response was the 59% who backed federal spending on charging stations, Gallup reported.

In between, the pollsters found that 75% backed providing tax incentives to businesses to promote their use of wind, solar and nuclear power and 71% supported setting higher fuel efficiency standards for cars, trucks and buses

Also, 62% favored establishing strict limits on the release of methane in the production of natural gas, while 61% backed providing tax credits to individuals who purchase electric vehicles.

All six of the proposals were included in President Joe Biden's $1.75 trillion Build Back Better Act introduced last year, which stalled in the Senate when two key Democrats, Sens. Joe Manchin of West Virginia and Kristin Sinema of Arizona, withheld their support for the measure in December, Manchin said he would not vote for the bill, citing factors including inflation worries, the COVID-19 pandemic and "geopolitical unrest."

RELATED Gallup poll: 1 in 3 Americans have recently experienced extreme weather

Some policies to boost the use of clean energy and electric vehicles were included in a bipartisan, $1.2 trillion infrastructure bill passed last year.

On a broader topic relating to climate change, the new Gallup Poll found that a smaller 53% majority said they are more concerned about the risk to the environment of not passing such proposals than they are about potential harm to the economy.

Some 43%, meanwhile. indicated they are more concerned about the potential harm to the economy and deficit if the such measures are passed.

RELATED Gallup poll: 44% of Americans worry a 'great deal' about environment

On a partisan level, solid majorities of Republicans favored some of the climate change measures, including 78% who backed tax credits for installing home-based clean energy systems and 62% who agreed with providing tax incentives to businesses to promote their use of wind, solar and nuclear power.

Only 36% of Republicans, however, supported tax credits to individuals who purchase electric vehicles.

17-year Neptune study reveals surprising temperature changes

The study's astronomers have been fixated on the summertime season that's occurred in the planet's southern hemisphere since 2005.


The image of the planet Neptune on the left was obtained during the testing of the Narrow-Field adaptive optics mode of the MUSE instrument on ESO’s Very Large Telescope. The image on the right is a comparable image from the NASA/ESA Hubble Space Telescope. Note that the two images were not taken at the same time so do not show identical surface features. 

Photo by ESO/P. Weilbacher (AIP)/NASA, ESA, and M.H. Wong and J. Tollefson/UC Berkeley

April 11 (UPI) -- The heating-and-cooling changes of Neptune's atmospheric and global temperatures have caught the attention of the astronomers who have monitored them over 17 years, a study released Monday shows.

The expert international team spent nearly two decades keeping a close watch on the gaseous planet's temperatures using ground-based telescopes, including the European Southern Observatory's Very Large Telescope.

What they found reveals an "unexpected" drop in Neptune's global temperatures followed by its south pole dramatically warming up, according to the study published in the Planetary Science Journal.

"Since we have been observing Neptune during its early southern summer, we expected temperatures to be slowly growing warmer, not colder," the study's lead author, Michael Roman, a postdoctoral research associate at the United Kingdom's University of Leicester, said in a news release.

While Neptune is like Earth in that its seasons change based on its orbit of the sun, Neptune's seasons last about 40 years, according to the European Southern Observatory.

A single year on Neptune, which is the most distant giant planet from the sun, equals 165 Earth years.

It's about 2.8 billion miles away from Earth.

This composite shows thermal images of Neptune taken between 2006 and 2020. The first three images (2006, 2009, 2018) were taken with the VISIR instrument on ESO’s Very Large Telescope while the 2020 image was captured by the COMICS instrument on the Subaru Telescope (VISIR wasn’t in operation in mid-late 2020 because of the pandemic). After the planet’s gradual cooling, the south pole appears to have become dramatically warmer in the past few years, as shown by a bright spot at the bottom of Neptune in the images from 2018 and 2020. 

Image by ESO/M. Roman, NAOJ/Subaru/COMICS

The study's astronomers have been fixated on the summertime season that's occurred in the planet's southern hemisphere since 2005, closely examining any temperature changes after the summer solstice.

They've pieced together nearly 100 thermal-infrared images of Neptune taken over 17 years to study those trends in deeper detail.

They recorded an average global temperature drop of 8 degrees Celsius, or 46.4 degrees Fahrenheit, between 2003 and 2018.

Yet another surprising finding came with the dramatic warming of the eighth planet's south pole during the last two years of observations.

Between 2018 and 2020, experts observed a rapid increase of 11 C, or 51.8 F. It's an unusual finding, as this level of rapid polar warming has never before been observed on Neptune, according to researchers.

"Our data cover less than half of a Neptune season, so no one was expecting to see large and rapid changes," said Glenn Orton, the study's co-author and senior research scientist at Caltech's Jet Propulsion Laboratory.

The astronomers are not yet certain what caused Neptune's unexpected temperature variations.

They plan to continue observing the changes in the coming years.

SPIRIT ANIMAL

Albino deer caught on camera next to Missouri road

April 11 (UPI) -- A Missouri man captured video of his close encounter with an albino deer he spotted standing at the side of a road.

Dale Richardson posted a video to Facebook showing the all-white deer he spotted standing just a few feet from a road in Marshfield.

Richardson said he has seen the albino white-tailed deer wandering in the area on two previous occasions.

Francis Skalicky, of the Missouri Department of Conservation, said the albino deer, sometimes known as a "ghost deer," is known to officials.

"This particular one around Marshfield we've actually got several reports of," Skalicky told KOLR-TV. "She has been around there for at least a few months."

The department said about one in 30,000 deer is born albino, meaning their bodies lack all pigment.

"One in 30,000 sounds like a rare ratio, which it is. However, when you have over a million deer in Missouri, which we do, that means you will probably have a few albino deer a year," Skalicky said. "We get reports of them around the state."

Study: Psychedelic mushroom ingredient helps reduce depression


Psilocybin, the ingredient that gives psychedelic mushrooms their mind-altering effects, appears to have therapeutic benefits for people with depression, according to a new study.

 File photo by Shots Studio/Shutterstock.


April 11 (UPI) -- Psilocybin, the ingredient that gives so-called psychedelic mushrooms their mind-altering effects, helps reduce the symptoms of depression, a study published Monday by Nature Medicine found.

Based on brain scans of roughly 60 people receiving the compound as a treatment for depression, it appears to foster improved communication between different regions of the brain, even after its hallucinogenic effects have worn off, the researchers said.

This may be how psilocybin works as a treatment for depression and other mental health disorders, they said.

"These findings are important because for the first time, we find that psilocybin works differently from conventional antidepressants," study co-author David Nutt said in a press release.

RELATED Magic mushroom' therapy may interact with other medicines

It appears to work by "making the brain more flexible and fluid, and less entrenched in the negative thinking patterns associated with depression," said Nutt, head of the Imperial Center for Psychedelic Research at Imperial College in London.

Psilocybin is one of a number of psychedelics being explored as a potential therapy for mental health disorders.

Several studies have examined the use of a synthesized form of the drug to treat patients with depression and anxiety, with promising results.

RELATED 'Magic mushroom' drug psilocybin edges toward mainstream therapy

These findings, taken from two combined studies, reveal that people who responded to psilocybin had evidence of increased brain connectivity both during their treatment and up to three weeks later, the researchers said.

This enhanced connectivity was associated with self-reported improvements in their depression, according to the researchers.

Patterns of brain activity in depression can become rigid and restricted, leading to repetitive negative thinking, they said.

RELATED Study finds 'magic mushroom' hallucinogen as good as antidepressants

Similar changes in brain connectivity were not seen in those treated with a commonly used prescription antidepressant, which indicates the psychedelic may work differently in treating the condition, the researchers said.

For the two studies, the researchers analyzed functional magnetic resonance imaging, or fMRI, scans of the brains of nearly 60 participants, about half of whom received psilocybin, while the remainder were treated with the anti-depressant escitalopram.

All participants also attended talking therapy sessions with registered mental health professionals. Brain scans were taken before and then one day or three weeks after participants received drug therapy, the researchers said.

Both studies found that depression patients treated with psilocybin experienced improvement in their symptoms, based on responses to clinical questionnaires, the data showed.

Analysis of the brain scans revealed altered communication or connectivity between brain regions, particularly those that are thought to be more segregated in depressed patients, according to the researchers.

There was a correlation between this effect and symptom improvement in both studies, although the strength and duration of effect varied between participants, the researchers said.

However, the effect was strongest in participants who reported an improvement in their symptoms, they said.

Still, the researchers caution that though these findings are encouraging, they are based on studies conducted under controlled, clinical conditions, using a regulated dose of psilocybin formulated in a laboratory, with extensive psychological support from mental health professionals.

People with depression should not attempt to self-medicate with psilocybin, as taking magic mushrooms or psilocybin in the absence of these careful safeguards may not have a positive outcome, the researchers said.

"We don't yet know how long the changes in brain activity seen with psilocybin therapy last and we need to do more research to understand this," study co-author Robin Carhart-Harris said in a press release.

"We do know that some people relapse, and it may be that after a while their brains revert to the rigid patterns of activity we see in depression," said Carhart-Harris, a psychologist and neuroscientist at the University of California-San Francisco.

MOST LUNG CANCER VICTIMS NEVER SMOKED
Some smokers develop genetic defenses against lung cancer, study finds


Researchers may have discovered why only some smokers develop lung cancer. 

Photo by Myriams-Fotos/Pixabay

April 11 (UPI) -- Some cigarette smokers may have genes that protect them from the genetic mutations that cause lung cancer, a study published Monday by Nature Genetics found.

The analysis of the cells lining the lungs of both smokers and non-smokers, both with and without lung cancer, found that smokers had more of the genetic mutations that cause lung cancer even if they do not develop the disease, the data showed.

However, while the number of genetic mutations detected in lung cells increased in parallel with the amount and length of time people smoked, this increase stopped at a certain point -- 23 "pack-years," which equates to smoking one pack per day of cigarettes for 23 years, the researchers said.

This suggests that some long-time, heavy smokers are able to "suppress further mutation accumulation" because they have "proficient systems for repairing DNA damage or detoxifying cigarette smoke," study co-author Dr. Simon Spivack said.

RELATED Tobacco use declined among U.S. adults in 2020, CDC reports

Still, whether some smokers can indeed develop this protection and how they do so, needs to be confirmed in larger studies, he said.

"Some heavy smokers may develop resistance to these genetic mutations or inherit resistance to these mutations," Spivack, a professor of medicine, epidemiology and population health and genetics at Albert Einstein College of Medicine in New York City and a pulmonologist at Montefiore Health System, told UPI in a phone interview.

"However, this doesn't mean it's safe for some people to smoke -- we know the more people smoke, the more risk you have for developing lung cancer," he said.

RELATED Study: White people more likely than Black people to be screened for lung cancer

Nearly 240,000 people in the United States will be diagnosed with lung cancer this year, about 80% of them smokers, the American Cancer Society estimates.

However, although the majority of lung cancer cases involve smokers, not all smokers develop lung cancer, Spivack and his colleagues said.

About 13% of adults in the United States are active smokers, the lowest level since the 1960s, according to the Centers for Disease Control and Prevention.

RELATED Lung cancer screening has saved more than 10,000 lives in the U.S.

For this study, Spivack and his colleagues used a technology called single-cell multiple displacement amplification, which was developed by Einstein College of Medicine researcher Jan Vijg, and allows for genetic analysis of individual cells.

They used the approach to assess lung epithelial cells, or those lining the walls of the lungs, in 14 "never-smokers" ages 11 to 86 years and 19 smokers ages 44 to 81 years. The cells were collected from patients who were undergoing bronchoscopy for diagnostic tests unrelated to cancer, according to the researchers.

The analysis revealed that genetic mutations accumulated in the lung cells of both non-smokers and smokers as they age, the data showed.

"Age increases these mutations in everybody and smoking further increases them, even if you don't develop lung cancer" Spivack told UPI.

However, significantly more mutations were found in the lung cells of the smokers in the study, the researchers said.

The number of cell mutations detected in lung cells increased along with the number of pack years of smoking, with one pack-year equating to one pack of cigarettes smoked per day for one year, they said.

Still, the rise in genetic mutations in lung cells stopped after the 23 pack-years of exposure.

The findings could help identify smokers who are at higher risk for lung cancer and thus warrant close monitoring, the researchers said.

" We don't yet know whether or not our findings will inform future diagnosis or treatment of lung cancer, but it is a step in the right direction," Spivack said.

LA REVUE GAUCHE - Left Comment: Search results for LUNG CANCER 

CDC to begin month-long full agency review amid criticism over COVID-19 response


CDC Director Dr. Rochelle P. Walensky testifies before the House COVID-19 subcommittee at the U.S. Capitol in Washington on April 15, 2021. 

File Photo by Amr Alfiky/UPI | License Photo

April 11 (UPI) -- The Centers for Disease Control and Prevention will begin a month-long review and evaluation of the agency on Monday over its response to the COVID-19 pandemic.

Jim Macrae, who served as acting administrator of the Health Resources and Services Administration for two years, will conduct the comprehensive review of the agency, which has been scrutinized for its handling of the outbreak.

CDC Director Dr. Rochelle Walensky also selected three senior officials -- acting Principal Deputy Director Deb Houry, Chief Operating Officer Robin Baily and Chief of Staff Sherri Berger -- to gather feedback and solicit suggestions.

"Over the past year, I have heard from many of you that you would like to see CDC build on its rich history and modernize for the world around us," Walensky wrote in an agency-wide email announcing the review last week.

RELATED COVID-19 worldwide down to around million cases, 3,500 deaths per day

"I am grateful for your efforts to lean into the hard work of transforming CDC for the better. I look forward to our collective efforts to position CDC and the public health community for greatest success in the future."

Walensky said the review will focus on the CDC's core capabilities, including the public health workforce, data modernization, laboratory capacity, health equity, rapid responses to disease outbreaks and preparedness.

"At the conclusion of this collective effort, we will develop new systems and processes to deliver our science and program to the American people, along with a plan for how the CDC should be structured to facilitate the public health work we do," she wrote in the email.

Five former CDC heads have expressed support for the review.

 File Photo by David Tulis/UPI

The agency has faced criticism for its response dating back to former President Donald Trump's administration, which saw a slow rollout of tests and strict requirements for testing in the early days of the pandemic amid perceived resistance from Trump to act.

Criticism has persisted under President Joe Biden, when the CDC has been criticized for releasing complicated guidance on masking, quarantining and booster doses, as well as inflexibility in adapting to variants like Omicron.

"Never in its 75-year history has [the] CDC had to make decisions so quickly, based on often limited, real-time and evolving science," Walensky said.

"As we've challenged our state and local partners, we know that now is the time for CDC to integrate the lessons learned into a strategy for the future."

Five former CDC heads have expressed support for the review.

"This needs to be done as rapidly as possible because, heavens, you can create a scope so big and so complicated that we could do a 10-year study and it wouldn't really be enough," said Dr. Bill Roper, who served as CDC director from 1990 to 1993 under President George H.W. Bush. "I think her calling for a one-month review is a very smart idea."

Reforms that include making the CDC director a Senate-confirmed, Cabinet-type post have been proposed in the Senate, and have passed its health committee with bipartisan support. The proposals are awaiting a vote in the full chamber.

EXPROPRIATE PG&E
California utility to pay $55 million for massive wildfires

By OLGA R. RODRIGUEZ and MIKE LIEDTKE

 In this Aug. 15, 2019, file photo, a Pacific Gas & Electric worker walks in front of a truck in San Francisco. Pacific Gas & Electric has agreed to pay more than $55 million to avoid criminal prosecution for two major wildfires started by its aging equipment in 2019 and 2021, prosecutors announced. (AP Photo/Jeff Chiu, File)


SAN FRANCISCO (AP) — Pacific Gas & Electric, the nation’s largest utility, has agreed to pay more than $55 million to avoid criminal prosecution for two major wildfires sparked by its aging Northern California power lines and submit to five years of oversight in an attempt to prevent more deadly blazes.

The company didn’t acknowledge any wrongdoing in the settlement announced Monday with prosecutors in six counties ravaged by last year’s Dixie Fire and the 2019 Kincade Fire. The utility still faces criminal charges for a 2020 wildfire in Shasta County that killed four people.

The civil settlements are designed to accelerate payments to hundreds of people whose homes were destroyed so they can start rebuilding more quickly than those who suffered devastating losses in 2017 and 2018 blazes ignited by PG&E’s equipment. Those fires prompted the utility to negotiate settlements that included $13.5 billion earmarked for victims — money that still hasn’t been completely distributed.

The deal also thrusts the utility back into five years of independent oversight, similar to the supervision PG&E faced during its criminal probation after it was convicted of misconduct that contributed to a natural gas explosion that killed eight people in 2010.

Sonoma County District Attorney Jill Ravitch said that oversight was the biggest accomplishment to come from the settlement.

“We have limited tools and criminal law to deal with corporations and what we were able to do here was to get a five-year agreement that they will be overseen, that there will be an independent monitor, and that they will have to meet certain benchmarks,” she said Monday.

All told, PG&E has been blamed for more than 30 wildfires since 2017 that wiped out more than 23,000 homes and businesses and killed more than 100 people.

PG&E’s federal probation ended in late January, raising worries from the federal judge who tried to force the utility to reduce fire risks by requiring more maintenance and reporting. U.S. District Judge William Alsup warned that PG&E remained a “continuing menace to California” and urged state prosecutors to try to rein in the company that provides power to 16 million people.

In a joint statement covering five of the six counties that settled, prosecutors said PG&E will be “essentially on a five-year probation” to be overseen by Filsinger Energy Partners, which already acts as a safety monitor for California power regulators.

PG&E will have to underwrite the federal monitor’s costs, up to $15 million annually, in addition to the $55 million in other payments and penalties that the utility expects to incur in the settlement.

As part of their settlement, Sonoma County prosecutors agreed to drop 33 criminal charges filed last year that accused PG&E of inadvertently injuring six firefighters and endangering public health with smoke and ash from the Kincade Fire that began in October 2019.

Fire officials said a PG&E transmission line sparked the fire, which destroyed 374 buildings in wine country and caused nearly 200,000 people to flee as it burned through 120 square miles (311 square kilometers), the largest evacuation in county history.

Prosecutors in the other five counties were exploring criminal charges in last year’s Dixie Fire before cutting the deal that they said will result in far larger payouts than had they hauled PG&E into court. Because there were no deaths in the Dixie Fire, prosecutors said the utility would have paid a maximum penalty of about $330,000 if it had been found guilty in a criminal case.

Ravitch said state laws that limit punishment against a corporation to probation and fines helped motivate the settlement. She said if PG&E had been successfully prosecuted in the Sonoma County case it would have paid a fine of just $9.4 million, most of which would have gone to the state.

Instead, the county will now receive more than $20 million earmarked for nonprofits that help people affected by wildfires and for Santa Rosa Junior College so that it can expand fire safety and vegetation management programs. It will also reimburse the DA’s office for the costs of investigating and litigating the case, she said.

Even when PG&E pleaded guilty to 84 felony counts of involuntary manslaughter f or the deaths in the 2018 Camp Fire, the company was fined just $3.5 million.

In a statement, PG&E CEO Patti Poppe said the utility welcomed the chance to be more transparent — and ultimately more accountable — for its operations.

“We are committed to doing our part, and we look forward to a long partnership with these communities to make it right and make it safe,” Poppe said.

The money that that PG&E will pay as part of the settlements will account for a just sliver of its anticipated liabilities in the Kincade, Zogg and Dixie fires. As of December 31, PG&E estimated it will likely be held responsible for at least $2.3 billion in losses stemming from those wildfires. Some of the estimated $1.15 billion in damages caused by the Dixie Fire may be paid by a state-backed insurance fund that California lawmakers created after PG&E filed for bankruptcy in 2019.

The Dixie Fire burned nearly 1 million acres (3,900 square kilometers) in Butte, Plumas, Lassen, Shasta, and Tehama counties and destroyed more than 1,300 homes and other buildings. The blaze started on July 13, 2021 when a tree hit electrical distribution lines west of a dam in the Sierra Nevada, according to investigators with the California Department of Forestry and Fire Protection.

The settlement for the Dixie Fire was made by district attorneys in Plumas, Lassen, Tehama, Shasta and Butte counties, which will receive nearly $30 million.

Although her office participated in the Dixie Fire settlement, Shasta County District Attorney Stephanie Bridgett said she will continue to pursue a criminal case related to the Zogg Fire, which killed four.

___

Liedtke reported from San Ramon, California.

PG&E avoids criminal charges for role in Dixie, Kincade wildfires

Last year's massive Dixie fire destroyed 963,309 acres.

An aerial view taken on August 12 shows the devastation caused by the Dixie Fire after it burned through Greenville's historic Gold Rush-era town in California. 

File Photo courtesy of California Office of Emergency Services | License Photo

April 11 (UPI) -- Pacific Gas and Electric Company won't be criminally charged for its involvement in igniting the 2019 Kincade fire and the 2021 Dixie fire, a group of California district attorneys announced Monday.

The Kincade fire broke out in late October 2019. It destroyed more than 77,700 acres of vegetation across Sonoma County, Calif., over 13 days. Regulators concluded the fire was sparked by PG&E equipment.

Last year's massive Dixie fire, the second-largest in California history, ripped through 963,309 acres.


Melted aluminum attests to the heat of the wildfire in Greenville, Calif., on August 12. 

File Photo by Terry Schmitt/UPI | License Photo

Prosecutors representing the impacted counties of Plumas, Lassen, Tehama, Shasta and Butte settled with PG&E for the company's role in the Dixie wildfire that raged for 103 days, according to the California Department of Forestry and Fire Protection.

As part of the settlement on both cases, the utility has until the summer to pay people initially left homeless in the Dixie fire.

An independent safety monitor may also oversee the company, at the request of the district attorneys in the settlement.

Bricks from the Masonic Lodge litter the street in Greenville, Calif., on August 12. 

File Photo by Terry Schmitt/UPI | License Photo

PG&E will have to pay nearly $30 million to organizations and local charities that came to the aid of those directly impacted by the fire.

The company must also keep making expensive improvements in the safety and reliability of its infrastructure in the North State region of California.

PG&E is required to pay penalties and investigation costs to the district attorneys' offices, and cannot raise raise to cover money lost in the settlement.

In 2020, the company pleaded guilty to 84 counts of involuntary manslaughter in the 2018 Camp Fire in California.

EXPLAINER: Where do US opioid trials, settlements stand?
By GEOFF MULVIHILL

Signs are displayed at a tent during a health event on June 26, 2021, in Charleston, W.Va. The effort to hold drug companies, pharmacies and distributors accountable for their role in the opioid crisis has led to a whirlwind of legal activity around the United States. New legal settlements are being reached practically every week to provide governments money to fight the crisis, and in some cases funds for medicines to reverse overdoses or to help with treatment. (AP Photo/John Raby, File)

The effort to hold drug companies, pharmacies and distributors accountable for their role in the opioid crisis has led to a whirlwind of legal activity around the U.S. that can be difficult keep tabs on.

Three trials are underway now, in Florida, West Virginia and Washington state. New legal settlements are being reached practically every week to provide governments money to fight the crisis and in some cases funds for medicines to reverse overdoses or to help with treatment. More settlements are likely on the way.

More than 3,000 lawsuits have been filed by state and local governments, Native American tribes, unions, hospitals and other entities in state and federal courts over the toll of opioids. Most allege the industry created a public nuisance in a crisis that has been linked to the deaths of 500,000 Americans over the past two decades.

Collectively, businesses have faced settlements, judgements and civil and criminal penalties totaling more than $47 billion in the last 15 years. The three main entities targeted are the companies that manufactured and sold the pills; the businesses that distributed them; and the pharmacies that dispensed them.

An overview of the litigation and settlements involving the various companies:

PURDUE PHARMA

Purdue is the maker of OxyContin, an extended-release version of oxycodone that packed higher doses into pills. The drug, released in 1996, became a heavily marketed blockbuster drug — and is associated closely with the epidemic’s first wave.

Like other opioids, it was promoted not just for post-surgery and cancer pain but for chronic pain — an area where doctors previously were reluctant to prescribe such powerful drugs.

Faced with thousands of lawsuits, the company went into bankruptcy protection in 2019 to help reach a settlement.

A deal is now in place, but it’s not final.

It calls for members of the Sackler family who own the company to give up their stakes, making way for it to become a new entity — to be known as Knoa Pharma — with profits funding the fight against the opioid crisis. Additionally, family members are to pay $5.5 billion to $6 billion over time, with a portion of the money going to individual victims.

Earlier this year, three members of the family attended an online hearing in which parents described losing children to addictions that started with OxyContin, and people recovering from addictions described their journeys.

As part of the exchange, Sackler family members would get protection from lawsuits over opioids.

For the settlement to be finalized, a higher court must overturn a judge’s ruling that threw out an earlier version of the deal. A hearing on that is scheduled for April 29 before the U.S. 2nd Circuit Court of Appeals in New York.

In the meantime, activists and some members of the U.S. Senate are asking the Justice Department to consider charges against family members.

OTHER DRUGMAKERS

In a major court victory for drugmakers last year, a California judge ruled against some local governments in their case against pharmaceutical companies Johnson & Johnson, Endo International and Teva Pharmaceutical Industries.

Some of those drugmakers — Johnson & Johnson, Allergan and Teva — are now on trial in West Virginia.

But companies have largely been settling suits.

Mallinckrodt, which was a leading producer of generic oxycodone, also used bankruptcy court to reach a settlement, agreeing to a $1.6 billion nationwide deal in 2020.

Johnson & Johnson has agreed to a $5 billion nationwide settlement. It was announced alongside a separate settlement involving the three biggest drug wholesalers. The company’s Janssen subsidiary stopped selling its fentanyl patches and pain pills in the U.S. in 2020. J&J was also the first drugmaker to be held liable for the opioid crisis in a trial, though the Oklahoma state Supreme Court later overturned the ruling.

Endo made the opioid Opana, which was eventually removed from the market. The company has been reaching individual settlements with states. Deals since last year with Florida, New York, Texas, West Virginia and some district attorneys in Tennessee have totaled well over $200 million.

Late last year, a New York jury found Teva partly responsible for the state’s opioid crisis through its marketing of the fentanyl drugs Actiq and Fentora. Most of the other companies the state and two counties sued settled before or during a trial last year. A separate trial is to be held to determine damages.

Since the New York trial, Teva has reached settlements with Texas, Florida and Rhode Island totaling more than $250 million. It will also provide drugs to reverse overdoses and treat addictions.

Allergan, now a subsidiary of AbbVie, has been settling suits involving the extended-release morphine pill Kadian. It reached one major settlement with New York last year. Since then, it has been part of the multi-company settlements in Florida and Rhode Island.

Executives from drugmaker Insys were convicted in 2019 of bribing doctors across the U.S. to prescribe their sublingual fentanyl spray Subsys. Company founder John Kapoor was sentenced to 5 1/2 years in federal prison.

The company also paid $225 million to resolve federal investigations into allegations that it paid kickbacks and used other illegal marketing tactics.

DISTRIBUTION COMPANIES

The three big national companies — AmerisourceBergen, Cardinal Health and McKesson — finalized their settlement, worth a total of $21 billion over 18 years, in February.

The deal, combined with Johnson & Johnson’s, is expected to be the single biggest settlement between companies in the drug industry and governments.

The total amounts include separate settlements covering all federally recognized Native American tribes.

With settlement money starting to flow to state and local governments, officials are figuring out how to prioritize it. The funds are arriving at a precarious time: The number of U.S. overdose deaths from all drugs topped 100,000 in a 12-month period for the first time last year. The majority of those deaths are from opioids — and particularly illicit synthetic versions including fentanyl.

Unlike the tobacco settlements of the 1990s, there are safeguards intended to steer most of the opioid settlement funds to addressing the crisis. Public health experts have ideas for how to do that, but the decisions are up to government officials.

The distribution companies also went to trial last year in West Virginia. A judge has not yet ruled.

Closing arguments in Washington state’s trial against the distributors are expected this week.

PHARMACIES

Pharmacy chains have been sued less often than companies that make or distribute opioids. In one groundbreaking case, a federal jury in Ohio last year found CVS, Walgreens and Walmart recklessly distributed massive amounts of pain pills in Lake and Trumbull counties.

Late last month, CVS settled in Florida. That left Walgreens to go to trial Monday.

CONSULTING COMPANY

Global consulting firm McKinsey & Company also reached deals last year with the states, Washington, D.C., and U.S. territories for advising businesses on how to sell more prescription opioids amid the overdose crisis. Those settlements totaled more than $600 million.

A group of U.S. senators is pushing for a federal investigation, saying there were conflicts when the company consulted on opioid-related issues both for companies and the U.S. Food and Drug Administration.

AMERICAN EXCEPTIONALISM
Efforts to make protective medical gear in US falling flat

By DAVID A. LIEB

1 of 8

Jim Schmersahl, owner of Halcyon Shades, poses in a "clean room" used in making N-95 masks at the company's production facility Friday, March 18, 2022, in University City, Mo. Halcyon is small company that normally makes window shades, but when the pandemic hit, its sales plummeted. Halcyon applied for the state grants to make PPE as a way to try to keep its employees at work and keep the company afloat. (AP Photo/Jeff Roberson)


UNIVERSITY CITY, Mo. (AP) — When the coronavirus pandemic first hit the U.S., sales of window coverings at Halcyon Shades quickly went dark. So the suburban St. Louis business did what hundreds of other small manufacturers did: It pivoted to make protective supplies, with help from an $870,000 government grant.

But things haven’t worked out as planned. The company quit making face shields because it wasn’t profitable. It still hasn’t sold a single N95 mask because of struggles to get equipment, materials and regulatory approval.

“So far, it has been a net drain of funds and resources and energy,” Halcyon Shades owner Jim Schmersahl said.

Many companies that began producing personal protective equipment with patriotic optimism have scaled back, shut down or given up, according to an Associated Press analysis based on numerous interviews with manufacturers. Some already have sold equipment they bought with state government grants.

As COVID-19 was stressing hospitals and shuttering businesses in 2020, elected officials touted the need to boost U.S. production of protective gear: “All this stuff should be made in the United States and not in China,” Florida Gov. Ron DeSantis said in remarks echoed by others.

Yet many manufacturers who answered the call have faced logistical hurdles, regulatory rejections, slumping demand and fierce competition from foreign suppliers. On April 1, Florida-based American Surgical Mask Co. became one of the latest to close.

“I’m just done with the fight,” CEO Matt Brandman told the AP.

After the initial scramble for PPE subsided, many industry newcomers faced difficulty selling products. Government agencies sometimes wanted huge quantities at tough-to-meet deadlines. Hospital systems tended to contract with established suppliers. Retail sales waned after every virus surge.

“At the end of the day, when everybody said they wanted American-made, nobody’s buying, not even the state,” said Tony Blogumas, vice president of Green Resources Consulting, a rural Missouri firm that received an $800,000 state grant but has sold only a few thousand masks. “We’re kind of upset about the whole situation.”

Missouri Gov. Mike Parson also is disappointed. His administration divided $20 million in federal COVID-19 relief funds among 48 businesses for the production of masks, gowns, sanitizer and other supplies. Parson hoped to seed a permanent field of manufacturers.

“I’m still a firm believer in that — that we need to be making PPE here in this state,” Parson said. “Unfortunately, a lot of entities went right back to where they were getting it before.”

The onset of the pandemic revealed that the U.S. was highly dependent on foreign countries for protective gear. When China limited exports because of its own battle against COVID-19, U.S. stockpiles plummeted. Prices skyrocketed as federal officials, governors and health care systems competed for supplies.

Though federal stockpiles have been replenished, shriveling domestic production has raised concerns that state governments, medical facilities and others could again get stuck scrambling for gear during a future pandemic.

The AP identified more than $125 million in grants to spur production of pandemic supplies made to over 300 business in 10 states — Alabama, Hawaii, Indiana, Kansas, Louisiana, Maryland, Massachusetts, Missouri, New York and Ohio. It’s possible that grants were awarded in additional states, but there is no central clearinghouse to track them.

In November 2020, Alabama awarded one of the single largest grants — nearly $10.6 million from federal pandemic relief funds — to HomTex Inc. The company was to equip a new Selma facility to make 250 million surgical masks and 45 million N95 masks annually. The plant returned $1.8 million of the state grant and has yet to make anything due to a lack of customers.

“I can’t produce product that I can’t sell,” HomTex President Jeremy Wootten said.

Other companies also had trouble living up to political hype.

In October 2020, New York announced eight grants that then-Lt. Gov. Kathy Hochul, now the governor, said were “a model for how we build back better for the post-pandemic future.” Those included $800,000 for newly formed Altor Safety and $1 million for startup firm NYPPE.

But NYPPE’s equipment wasn’t ready until February 2021, by which time the market had changed, President Connor Knapp said.

So Knapp tapped the brakes on his plans. NYPPE still hasn’t sold any N95 masks because it lacks regulatory approval. It just recently scaled up production of surgical masks, after obtaining a U.S. Food and Drug Administration certification that came with its purchase of Altor Safety.

Some PPE manufacturers point to federal regulations as part of the reason for their struggles. Three-ply masks need FDA approval to be marketed for medical use — an important designation for building a long-term customer base.

That process can be time-consuming. Facing delays, Angstrom Manufacturing in Missouri ended up buying another business that already had FDA approval, President Chris Carron said. By then, it was fall 2021 — a year after it received a state grant.

Angstrom Manufacturing president Chris Carron poses for a photo with machinery the company uses to make surgical masks Wednesday, March 23, 2022, in Ste. Genevieve, Mo. (AP Photo/Jeff Roberson)

Companies need approval from the National Institute for Occupational Safety and Health to market products as N95 respirators, which filter at least 95% of airborne particles.

During the first two years of the pandemic, NIOSH approved 30 new manufacturers — more than seven times the typical number during a similar pre-pandemic period, according to agency data. Some applications remain pending, while numerous others were denied.

Halcyon Shades’ N95 certification was rejected in October because its samples didn’t have head straps attached. While the company works on another application, its equipment sits idle inside the clear plastic-sheet walls of a “clean room” specially built to shield materials from airborne contaminants. Partially finished masks remain paused on a conveyor belt, waiting to be deposited into a cardboard box.

Without federal approval, “we’re just dead in the water,” said Schmersahl, the company owner.

Progress reports filed with the Missouri Department of Economic Development show that nearly all its PPE grant recipients faced challenges by July 2021, especially with sales.

Jim Schmersahl, owner of Halcyon Shades, poses with a machine used to make N-95 masks Friday, March 18, 2022, in University City, Mo. (AP Photo/Jeff Roberson)

Patriot Medical Devices, which received $750,000 from Missouri, hired nearly 100 people as it cranked out millions of masks during a COVID-19 surge in late 2020 and early 2021, CEO Rick Needham said. Fewer than 10 employees remain.

“We felt it was our patriotic duty to do something to help solve the problem,” Needham said. But, he added, “It’s frankly a little bit of a dysfunctional business model at this point.”

Ohio awarded $20.8 million to 73 businesses to manufacture pandemic-related supplies, according to state data. Of 60 businesses that complied with a recent reporting deadline, more than one-third no longer produced PPE by the end of 2021.

Cleveland Veteran Business Solutions, which received a $500,000 grant to get into the PPE business, made about 5 million surgical masks beginning in August 2020. It ultimately halted production in the face of cheaper imports and sold its machines this year, co-founder Taner Eren said.

“It was surprising and disappointing strategically that there wasn’t support for a local PPE manufacturing industry,” Eren said.

The business was among several dozen that banded together to form the American Mask Manufacturer’s Association with the goal of sustaining the industry. The group’s membership has dwindled as more and more go out of business.

Association organizers say the industry has reached a critical point. They want the federal government to treat PPE manufacturers like the nation’s defense industry — entering into long-term contracts to perpetually replenish a stockpile for future pandemics or emergencies.

“If the federal government doesn’t come in and help support the U.S. manufacturing base, it’s almost certainly going to go back to China, and we’ll be just as vulnerable as we were in early 2020 and 2019,” said Brent Dillie, the association chairman and co-founder of Premium-PPE, a Virginia manufacturer started during the pandemic that has shed about two-thirds of its roughly 300 employees.

Infrastructure legislation signed by President Joe Biden took a step toward bolstering domestic suppliers. Effective in February, it required new contracts for PPE purchased by the departments of Health and Human Services, Homeland Security and Veterans Affairs to run for at least two years and be awarded to U.S. producers — unless there’s not sufficient quantity and quality at market prices.

The health and veterans departments said they haven’t bought anything yet. Homeland Security hasn’t answered the AP’s questions. Documents show the government solicited bids due Dec. 6 for up to 381 million U.S.-made surgical masks over three years for its stockpile. No deal has been announced.

Other documents show the government is looking to contract with three major suppliers — 3M, Moldex, and Owens & Minor — for a total of $115 million in U.S-made N95 masks over three years. A justification document says noncompetitive contracts are necessary to preserve capacity for future coronavirus surges or emergencies.

The Biden administration also formed a task force of experts from federal agencies, health care providers, PPE manufacturers and distributors to develop a national strategy for ensuring a “resilient public health supply chain.” Its work is expected to extend for years.

Some manufacturers said they can’t wait long for a federal life preserver.

Dentec Safety Specialists is wrapping up a contract to supply 125,000 rubber reusable respirators and 500,000 filtration cartridges from its Kansas facility for the national stockpile, said President Claudio Dente. It needs more orders soon to prevent layoffs, he said.

“I thought that COVID would really change the mindset of the people, the governments and manufacturing,” Dente said. But he added: “The general marketplace is reverting back to their old ways -- meaning looking to buy product from China.”

National Urban League finds State of Black America is grim

A girl in a stroller plays with a squirt gun as a woman pushes her past a Black Lives Matter mural in the Shaw neighborhood in Washington, Monday, July 13, 2020. The National Urban League released its annual report on the State of Black America on Tuesday, April 12, 2022, and its findings are grim. This year’s Equality Index shows Black people still get only 73.9 percent of the American pie white people enjoy. (AP Photo/Andrew Harnik, File)


ATLANTA (AP) — The National Urban League released its annual report on the State of Black America on Tuesday, and its findings are grim. This year’s Equality Index shows Black people still get only 73.9 percent of the American pie white people enjoy.

While Black people have made economic and health gains, they’ve slipped farther behind whites in education, social justice and civic engagement since this index was launched in 2005. A compendium of average outcomes by race in many aspects of life, it shows just how hard it is for people of color to overcome systemic racism, the civil rights organization says.

“These numbers change so little and so slowly. What it tells me is that this institutional disparity based on race seems to be built into American society,” National Urban League President Marc Morial said in an interview.

The index shows not only that median household income for Black people, at $43,862, is 37% less than that of white people, at $69,823. Black people also are less likely to benefit from home ownership, the engine of generational wealth in America. Census data shows Black couples are more than twice as likely as whites to be denied a mortgage or a home improvement loan, which leads to just 59% of the median home equity white households have, and just 13% of their wealth.

“In that area of wealth, we’ve seen almost no change, none, since the civil rights days,” Morial said. “The wealth disparity has gotten wider.”

Among dozens of health measures, one stands out: Life expectancy has declined slightly for African Americans, so a Black child born today can expect to live to 74.7, four years less than a white baby. And lifelong inequities loom: Black women are 59% more likely to die as a result of bearing a child, and 31% more likely to die of breast cancer. Black men are 52% more likely to die of prostate cancer.

Overdoses afflict the races about equally, while white people are 55% more likely to drink themselves to death through cirrhosis or chronic liver disease. Among people 15-24, white people are more than twice as likely to commit suicide, while Black men are nine times more likely to die by homicide.

Educational gaps abound: Black and white preschoolers are roughly equally prepared, but the classrooms they enter are starkly different. Schools with more minority students are more likely to have inexperienced, less trained and even uncertified teachers. Fewer of these students are enrolled in the STEM classes that can lead to higher-paying jobs. Black students are less likely to graduate college.

The index uses U.S. Justice Department statistics to chart social justice differences, noting that Black people have been more than twice as likely as white people to experience threats or uses of force during police encounters, and three times more likely to be jailed if arrested. In 2020, they were 93% more likely to be victims of hate crime.

Measuring civic engagement, the index cites 2020 Census data showing that white people are about 5% more likely to be registered and to actually vote than Black people.

Morial chose to release the report in Atlanta, where a concentration of historically Black colleges have long represented high achievement among African Americans, in part because its survey shows a declining faith among young people that voting can make a difference. The Urban League is responding by launching a “Reclaim Your Vote” campaign.

“Georgia is ground zero for voter suppression. The legislature’s actions after Jan. 6 have been sweeping in their aggressiveness to suppress the vote,” Morial said. “We’ve got to remain resolute, to push back against this. We cannot give in. We cannot give up.”