Thursday, August 18, 2022

NASA scientists study how to remove planetary “photobombers”

Peer-Reviewed Publication

NASA/GODDARD SPACE FLIGHT CENTER

Artist's concept of Earth-like Exoplanet 

IMAGE: ARTIST’S CONCEPT OF KEPLER-186F, AN EARTH-SIZE EXOPLANET ORBITING A RED DWARF STAR IN THE CONSTELLATION CYGNUS. view more 

CREDIT: NASA/TIM PYLE

Imagine you go to a theme park with your family and you ask a park employee to take a group photo. A celebrity walks by in the background and waves at the camera, stealing the focus of the photo. Surprisingly, this concept of “photobombing” is relevant to astronomers looking for habitable planets, too.

When scientists point a telescope at an exoplanet, the light the telescope receives could effectively be “contaminated” by light from other planets in the same star system, according to a new NASA study. The research, published in the Astrophysical Journal Letters on Aug. 11, modeled how this “photobombing” effect would impact an advanced space telescope designed to observe potentially habitable exoplanets and suggested potential ways to overcome this challenge.

“If you looked at Earth sitting next to Mars or Venus from a distant vantage point, then depending on when you observed them, you might think they’re both the same object,” explains Dr. Prabal Saxena, a scientist at NASA’s Goddard Space Flight Center in Greenbelt, Maryland, who led the research.

Saxena uses our own solar system as an analog to explain this photobombing effect.

“For example, depending on the observation, an exo-Earth could be hiding in [light from] what we mistakenly believe is a large exo-Venus,” said Dr. Saxena. Earth’s neighbor Venus is generally thought to be hostile to habitability, with surface temperatures hot enough to melt lead – so this mixing could lead scientists to miss out on a potentially habitable planet.

Astronomers use telescopes to analyze light from distant worlds to gather information that may reveal whether they could support life. One light-year, the distance light travels in a year, is almost six trillion miles (over nine trillion kilometers), and there are about 30 stars similar to our Sun within roughly 30 light-years of our solar system.

This photobombing phenomenon, in which observations of one planet are contaminated by light from other planets in a system, stems from the “point-spread function” (PSF) of the target planet. The PSF is an image created due to diffraction of light (the bending or spreading of light waves around an opening) coming from a source and is larger than the source for something very far away (such as an exoplanet). The size of the PSF of an object depends on the size of the telescope aperture (the light-collecting area) and wavelength at which the observation is taken. For worlds around a distant star, a PSF may resolve in such a way that two nearby planets or a planet and a moon could seem to morph into one.

If that is the case, the data that scientists can gather about such an Earth analog would be skewed or affected by whatever world or worlds were photobombing the planet in question, which could complicate or outright prevent the detection and confirmation of an exo-Earth, a potential planet like Earth beyond our solar system.

This is a cartoon illustrating the planetary photobombing concept. Photobombers like Mars and the Moon could sneak into a picture of Earth, if you tried to observe it in a way similar to how scientists will try to find and understand potentially habitable worlds outside our solar system.

CREDIT

NASA/Jay Friedlander/Prabal Saxena


Saxena examined an analogous scenario in which otherworldly astronomers might be looking at Earth from more than 30 light-years away, using a telescope similar to that recommended in the 2020 Astrophysics Decadal Survey. “We found that such a telescope would sometimes see potential exo-Earths beyond 30 light-years distance blended with additional planets in their systems, including those that are outside of the habitable zone, for a range of different wavelengths of interest,” Saxena said.

The habitable zone is that region of space around a star where the amount of starlight would allow liquid water on a planet’s surface, which may enable the existence of life.

There are multiple strategies to deal with the photobombing problem. These include developing new methods of processing data gathered by telescopes to mitigate the potential that photobombing will skew the results of a study. Another method would be to study systems over time, to avoid the possibility that planets with close orbits would appear in each other’s PSFs. Saxena’s study also discusses how using observations from multiple telescopes or increasing the size of the telescope could reduce the photobombing effect at similar distances.

Discovering exoplanets and determining if any can support life is part of NASA’s mission to explore and understand the unknown, to inspire and benefit humanity.

The research was funded by NASA under award number 80GSFC21M0002 and was also funded in part by the Goddard Sellers Exoplanet Environments Collaboration (SEEC).

Who's looking out for aging doctors susceptible to cognitive decline?

Law professor at Case Western Reserve University says that state medical boards need to better identify clinicians with cognitive decline


CASE WESTERN RESERVE UNIVERSITY

Sharona Hoffman, the Edgar A. Hahn Professor of Law 
and co-director of the Law-Medicine Center 
Credit: Case Western Reserve University

Older physicians benefit from their many years of experience and the skills they have developed over decades of practice. At the same time, they may be at risk of cognitive decline, raising concerns about job performance deficits.

That’s according to Sharona Hoffman, the Edgar A. Hahn Professor of Law and co-director of the Law-Medicine Center, who said that state medical boards have a role to play in identifying clinicians with cognitive decline.

In an article “Physicians and Cognitive Decline: A Challenge for State Medical Boards,” published in Journal of Medical Regulation, she discusses what state medical boards currently do in this regard and analyzes whether they should do more. It also discusses relevant legal constraints and ethical obligations.

The article ultimately concludes that state medical boards would be wise to adopt late career screening programs that are carefully designed to balance the interest of clinicians and patient safety.

“Such programs could be implemented only after experts determine which preliminary tests and more comprehensive follow-up tests can best identify job-related cognitive impairment and at what age the testing program should commence,” she wrote. “Any testing program would have to include due process protections, efforts to provide reasonable accommodations to facilitate job performance, and a public relations campaign to build support among clinicians and professional organizations.”

Although the article focuses on state medical boards, its analysis and recommendation are relevant to all state licensing boards that oversee health care providers.

This article follows an article Hoffman published in the spring in the Wake Forest Law Review, entitled “Cognitive Decline and the Workplace.” That article explores the topic of cognitive decline more generally and analyzes what employers can and cannot do to address concerns about it in the workforce.

Musical tests can detect mental deterioration in old age


Integration of music with analysis of electrical brain activity

Peer-Reviewed Publication

TEL-AVIV UNIVERSITY

Neta Maimon 

IMAGE: NETA MAIMON view more 

CREDIT: TEL AVIV UNIVERSITY

Researchers at Tel Aviv University have developed a method that employs musical tests and a portable instrument for measuring brain activity to detect cognitive decline in old age. According to the researchers, the method, which is based on the measurement of 15 minutes of electrical activity in the brain while performing simple musical tasks, can be easily implemented by any staff member in any clinic, without requiring special training. The researchers: “Our method enables routine monitoring and early detection of cognitive decline in order to provide treatment and prevent rapid, severe deterioration. Prophylactic tests of this kind are commonly accepted for a variety of physiological problems such as diabetes, high blood pressure or breast cancer; however, to date no method has yet been developed to enable routine, accessible monitoring of the brain for cognitive issues.” The researchers further note that tests of this kind are particularly important in light of increasing longevity and associated growth of the elderly population.

The study was led at Tel Aviv University by PhD student Neta Maimon from the School of Psychological Sciences and the Buchmann-Mehta School of Music, and Lior Molcho from Neurosteer Ltd, headed by Prof. Nathan Intrator from the Blavatnik School of Computer Science and the Sagol School of Neuroscience. Other participants included: Adi Sasson, Sarit Rabinowitz, and Noa Regev-Plotnick from the Dorot-Netanya Geriatric Medical Center. The article was published in the journal Frontiers in Aging Neuroscience.

As part of the study, the researchers developed a groundbreaking method combining a portable device for the measurement and innovative analysis of electroencephalography (EEG), developed by Neurosteer, and a short musical test of about 12-15 minutes, developed by Neta Maimon. During the test, the subject is connected to the portable EEG device by means of a adhesive band with only three electrodes attached to the forehead. The subject performs a series of musical-cognitive tasks according to audible instructions given automatically through earphones. The tasks include short melodies played by different instruments, with the subjects instructed to perform various tasks on them at varying levels of difficulty. For example, pressing a button each time any melody is played or pressing it only when the violin plays. In addition, the test includes several minutes of musically guided meditation designed to bring the brain to a resting state, as this state is known to indicate cerebral functioning in various situations.

Neta Maimon, who specializes in musical cognition, explains that music has great influence on different centers in the brain. On the one hand, music is known to be a quick mood stimulant, particularly of positive emotion. On the other hand, in different situations, music can be cognitively challenging, activating the frontal parts of the brain, especially if we try to concentrate on different aspects of the music, and at the same time perform a particular task.

According to Maimon, if we combine these two capabilities, we can create cognitive tests that are quite complex, yet also pleasant and easy to perform. Furthermore, music that is positive and reasonably rhythmic will enhance concentration and performance of the task. Thus, for example, the famous “Mozart effect,” showing improved performance on intelligence tests after listening to Mozart’s music, actually has nothing to do with Mozart’s music, but rather the fact that music creates a positive mood and stimulates us to a state that is optimal for performing intelligence and creativity tests.

Accordingly, the researchers hypothesized that with musical tools, it would also be possible to challenge the subjects to an extent that would enable testing of the brain’s frontal activity as well as raising their spirits, thus enhancing their performance on the test while the overall experience is pleasant.

The study included an experiment at the Dorot-Netanya Geriatric Medical Center. Neta Maimon: “Anyone hospitalized at Dorot, or any other geriatric rehabilitation institution, undergoes a standard test called “mini-mental,” designed to evaluate their cognitive condition as a routine part of the intake process. The test is conducted by an occupational therapist specially trained for it, and includes a variety of tasks. For example, enumerating the days of the week or months of the year backwards. In this test, up to 30 points can be accrued. A high score indicates normal cognition.

The experiment included the testing of 50 elderly people hospitalized at Dorot who scored 18-30 on the mini-mental test, indicating various levels of cognitive functioning. The participants performed the musical-cognitive tasks, administered automatically. The EEG device registered the electrical activity in the brain during the activity, with the results analyzed using machine learning technology. This allowed mathematical indices to be identified that were precisely correlated with the mini-mental test scores; in other words, we obtained new neuro-markers (brain markers) that may stand alone as indices of the subject’s cognitive status.

Maimon adds: “We have actually succeeded in illustrating that music is indeed an effective tool for measuring brain activity. The brain activity and response times to tasks correlated to the subjects’ cerebral conditions (correlating to the mini-mental score assigned to them). More importantly, all those who underwent the experiment reported that, on the one hand, it challenged the brain, but on the other it was very pleasant to perform”.

The researchers conclude: “Our method enables the monitoring of cognitive capability and detection of cognitive decline already in the early stages. all by simple and accessible means, with a quick and easy test that can be conducted in any clinic. This method is of special importance today due to the increase in longevity and accelerated population growth, particularly among the elderly. Today, millions of people around the world already suffer or are liable to suffer soon from cognitive decline and its dire consequences, and their number will only increase in the coming decades. Our method could pave the way towards efficient cognitive monitoring of the general population, and thus detect cognitive decline in its early stages, when treatment and prevention of severe decline are possible. It is therefore expected to improve the quality of life of millions around the world.”

Keren Primor Cohen, CEO, Ramot at TAU: “We are pleased that a company based on a technology developed at TAU continues its collaboration on creative and multidisciplinary research.

Ramot will continue to promote and invest in novel technologies, as well as help TAU researchers to maximize their research’s potential.”

Link to the article:

https://www.frontiersin.org/articles/10.3389/fnagi.2022.773692/full

Study finds newest generation of post-9/11 U.S. veterans experience similar, better outcomes than non-veterans in many aspects of their lives

First study to provide a holistic examination of how the health, vocational, financial and social well-being of the newest generation of U.S. military Veterans compared with non-veteran peers

Peer-Reviewed Publication

BOSTON UNIVERSITY SCHOOL OF MEDICINE

(Boston)—Prior research has examined how the post-military health and well-being of both the larger veteran population and earlier veterans differs from non-veterans. However, no study to date has provided a holistic examination of how the health, vocational, financial and social well-being of the newest generation of post-9/11 U.S. military veterans compares with their non-veteran peers.

Now a new study has found that these Veterans report similar or better outcomes than non-veterans in a number of life domains. This includes greater engagement in a number of positive health behaviors and better outcomes on some aspects of social well-being than non-Veterans.  

“The finding that post-9/11 Veterans reported greater engagement in some health-promoting behaviors is particularly interesting given that this finding contrasts with research on the Veteran population as a whole (including Veterans who served before 9/11),” explains corresponding author Dawne S. Vogt, PhD, research scientist in the Women’s Health Sciences Division, National Center for PTSD at VA Boston Healthcare System and professor of psychiatry at Boston University School of Medicine.

U.S. Veterans post-9/11 and non-veterans reported on their health and broader well-being as part of a confidential web-based survey in 2018. Although the researchers found that post-9/11 men and women veterans experienced poorer health status than non-Veterans, they reported greater engagement in a number of positive health behaviors (healthy eating and exercise) and were more likely to indicate having access to health care. Veterans also endorsed greater social well-being than non-veterans on several outcomes, whereas few differences were observed in vocational and financial well-being.

“Despite their greater vulnerability to experiencing health conditions, the newest generation of post-9/11 U.S. Veterans report experiencing similar or better outcomes than non-Veterans in many aspects of their lives. These findings underscore the value of examining a wider range of health and well-being outcomes in Veteran research and highlight a number of important directions for intervention, public health education, policy and research related to the reintegration of military veterans within broader civilian society,” said Vogt.

According to the researchers, the finding that post-9/11 veterans reported poorer health status than their peers, while not surprising due to their potential exposure to health risks in the military, supports the need for continued investment in the provision of high-quality health care in both the VA and community-based health-care settings. “Given that post-9/11 Veterans reported greater engagement in some health-promoting behaviors than their non-Veteran peers (diet, physical activity, and strength training), these efforts should also focus on preventing declines in veterans’ engagement in health-promoting behaviors as they move through their life course,” she added. In addition, findings support the need for greater attention to veterans’ strengths, as well as their vulnerabilities, in both research and public education efforts.

These findings appear online in the journal Social Science and Medicine – Population Health.

This material is based upon work supported by the United States Department of Veterans Affairs (VA), Veterans Health Administration, Patient Care Services, Health Outcomes Military Exposures Epidemiology Program.

Vogt D., Borowski S., Maguen S., Blosnich J.R., Hoffmire C.A., Bernhard P.A., Iverson K.M. & Schneiderman A., Strengths and vulnerabilities: Comparing post-9/11 U.S. veterans’ and non-veterans’ perceptions of health and broader well-being, SSM - Population Health (2022), doi: https:// doi.org/10.10

NUS researchers invent self-charging, ultra-thin device that generates electricity from air moisture

Using sea salt as an eco-friendly moisture absorbent, this rechargeable fabric-like ‘battery’ provides higher electrical output than a conventional AA battery – potentially powering everyday electronics

Peer-Reviewed Publication

NATIONAL UNIVERSITY OF SINGAPORE

Fabric_MEG_1 

IMAGE: ASSISTANT PROFESSOR TAN SWEE CHING (CENTRE), TOGETHER WITH DR ZHANG YAOXIN (LEFT) AND MR QU HAO (RIGHT), FROM NUS DEPARTMENT OF MATERIALS SCIENCE AND ENGINEERING HAVE DEVELOPED A SELF-CHARGING FABRIC THAT GENERATES ELECTRICITY FROM AIR MOISTURE. view more 

CREDIT: NATIONAL UNIVERSITY OF SINGAPORE

Imagine being able to generate electricity by harnessing moisture in the air around you with just everyday items like sea salt and a piece of fabric, or even powering everyday electronics with a non-toxic battery that is as thin as paper. A team of researchers from the National University of Singapore’s (NUS) College of Design and Engineering (CDE) has developed a new moisture-driven electricity generation (MEG) device made of a thin layer of fabric - about 0.3 millimetres (mm) in thickness - sea salt, carbon ink, and a special water-absorbing gel.

The concept of MEG devices is built upon the ability of different materials to generate electricity from the interaction with moisture in the air. This area has been receiving growing interest due to its potential for a wide range of real-world applications, including self-powered devices such as wearable electronics like health monitors, electronic skin sensors, and information storage devices.

Key challenges of current MEG technologies include water saturation of the device when exposed to ambient humidity and unsatisfactory electrical performance. Thus, the electricity generated by conventional MEG devices is insufficient to power electrical devices and is also not sustainable.

To overcome these challenges, a research team led by Assistant Professor Tan Swee Ching from the Department of Materials Science and Engineering under CDE devised a novel MEG device containing two regions of different properties to perpetually maintain a difference in water content across the regions to generate electricity and allow for electrical output for hundreds of hours.

This technological breakthrough was published in the print version of scientific journal Advanced Materials on 26 May 2022.


Long-lasting, self-charging fabric-based ‘battery’

The NUS team’s MEG device consists of a thin layer of fabric which was coated with carbon nanoparticles. In their study, the team used a commercially available fabric made of wood pulp and polyester.

One region of the fabric is coated with a hygroscopic ionic hydrogel, and this region is known as the wet region. Made using sea salt, the special water-absorbing gel can absorb more than six times its original weight, and it is used to harvest moisture from the air.

“Sea salt was chosen as the water-absorbing compound due to its non-toxic properties and its potential to provide a sustainable option for desalination plants to dispose of the generated sea salt and brine,” shared Asst Prof Tan.

The other end of the fabric is the dry region which does not contain a hygroscopic ionic hydrogel layer. This is to ensure that this region is kept dry and water is confined to the wet region.

Once the MEG device is assembled, electricity is generated when the ions of sea salt are separated as water is absorbed in the wet region. Free ions with a positive charge (cations) are absorbed by the carbon nanoparticles which are negatively charged. This causes changes to the surface of the fabric, generating an electric field across it. These changes to the surface also give the fabric the ability to store electricity for use later. 

Using a unique design of wet-dry regions, NUS researchers were able to maintain high water content in the wet region and low water content in the dry region. This will sustain electrical output even when the wet region is saturated with water. After being left in an open humid environment for 30 days, water was still maintained in the wet region demonstrating the effectiveness of the device in sustaining electrical output.

“With this unique asymmetric structure, the electric performance of our MEG device is significantly improved in comparison with prior MEG technologies, thus making it possible to power many common electronic devices, such as health monitors and wearable electronics,” explained Asst Prof Tan.

The team’s MEG device also demonstrated high flexibility and was able to withstand stress from twisting, rolling, and bending. Interestingly, its outstanding flexibility was shown by the researchers by folding the fabric into an origami crane which did not affect the overall electrical performance of the device.


The new moisture-driven electricity generation (MEG) device invented by researchers from the National University of Singapore can withstand twisting, rolling and bending. A small piece of the MEG device can generate up to 0.7 volts of electricity for over 150 hours.

CREDIT

National University of Singapore


Portable power supply and more

The MEG device has immediate applications due to its ease of scalability and commercially available raw materials. One of the most immediate applications is for use as a portable power source for mobile powering electronics directly by ambient humidity.

“After water absorption, one piece of power-generating fabric that is 1.5 by 2 centimetres in size can provide up to 0.7 volts (V) of electricity for over 150 hours under a constant environment,” said research team member Dr Zhang Yaoxin.

The NUS team has also successfully demonstrated the scalability of its new device in generating electricity for different applications. The NUS team connected three pieces of the power-generating fabric together and placed them into a 3D printed case that was the size of a standard AA battery. The voltage of the assembled device was tested to reach as high as 1.96V – higher than a commercial AA battery of about 1.5V – which is enough to power small electronic devices such as an alarm clock.

The scalability of the NUS invention, the convenience of obtaining commercially available raw materials as well as the low fabrication cost of about S$0.15 per metre square make the MEG device suitable for mass production.

"Our device shows excellent scalability at a low fabrication cost. Compared to other MEG structures and devices, our invention is simpler and easier for scaling-up integrations and connections. We believe it holds vast promise for commercialisation," shared Asst Prof Tan.

The researchers have filed a patent for the technology and are planning to explore potential commercialisation strategies for real-world applications.

View video at https://www.youtube.com/watch?v=8WOh-trN9cw