Wednesday, September 14, 2022

Putting sharks on the map: A new standard to identify important habitats

A new set of global criteria will help identify important areas for sharks, rays, and chimaeras to secure the protection they desperately need in the face of extinction.

Peer-Reviewed Publication

FRONTIERS

Map of important conservation areas for endangered shark species 

IMAGE: BASELINE MAP OF SHARK AREA-BASED CONSERVATION. view more 

CREDIT: IMAGE: HYDE ET AL

To date, shark, ray, and chimaera species have not been sufficiently considered in the planning of marine protected areas.  However, a publication in Frontiers in Marine Science by researchers from the IUCN SSC Shark Specialist Group, IUCN’s Ocean Team, and the IUCN Marine Mammal Protected Areas Taskforce have developed a new framework to fundamentally change how sharks are considered in the design of protected areas and therefore support the protection they desperately need in the face of extinction.

Ms Ciaran Hyde, Consultant to the IUCN Ocean Team, explained: “We still have so much to learn about many shark, ray, and chimaera species, but unfortunately several studies indicate that many protected areas are failing to adequately meet their needs. However, Important Shark and Ray Areas (ISRAs) will help to identify areas for these species using criteria which have been specifically designed to consider their biological and ecological needs.”

As apex predators, sharks provide many vital functions for maintaining a balanced ecosystem. Sharks shape fish communities, ensure a diversity of species, and even help our oceans sequester more carbon by maintaining seagrass meadows.

“Losing sharks, rays and chimaeras will not only affect the health of the entire ocean ecosystem, but also impact food security in many countries,” highlighted Lynn Sorrentino, IUCN Ocean Team Programme Officer.

Vulnerable to human threats

However, their apex status makes them more susceptible to anthropogenic threats. Many of these species are impacted by fishing, especially in tropical and coastal areas where large communities live along the coast and depend upon fish as their main source of protein.

As Dr Rima Jabado, Chair of the IUCN SSC Shark Specialist Group explained: “Sharks are a long-lived species: many take a long time to reach sexual maturity and then only give birth to a few young. This makes them particularly susceptible to fishing pressure and with an estimated 37% of species with an elevated risk of extinction, they are facing a biodiversity crisis. Results from the ISRA project will inform policy and ensure that areas critical to the survival of sharks, rays, and chimaeras are considered in spatial planning.”

Developed by experts, conservation agencies, and governments

Work on the ISRA Criteria was supported by the Save Our Seas Foundation. They were developed through a collaborative process involving shark experts, conservation agencies, and governments and include four criteria and seven sub-criteria. These consider the complex biological and ecological needs of sharks, including areas important to threatened or range-restricted species, the specific habitats that support life-history characteristics and vital functions (eg, reproduction, feeding, resting, movement), distinctive attributes, and the diversity of species within an area.

Dr Giuseppe Notarbartolo di Sciara, co-chair of the IUCN Marine Mammal Protected Areas Taskforce and Deputy Chair of the IUCN SSC Cetacean Specialist Group noted: “All efforts are being made to ensure that the ISRAs contain the best and most up-to-date place-based information that science can offer to decision makers, managers, and marine users. As the ISRA program proceeds by covering progressively the whole extent of the ocean (and relevant inland water) surface, a very broad involvement of the shark expert community world-wide is expected.”

By bringing together information from scientific publications, reports, databases and the expertise of individual shark experts, ISRAs are a powerful tool for governing bodies to develop policy and design protected areas.

Anthology highlights the value of pathways as cultural heritage

Book Announcement

UNIVERSITY OF GOTHENBURG

Path in the woods 

IMAGE: PATHWAYS LEAD US FORWARD AS WE WALK ALONG THEM AND ALSO TAKE US BACK IN HISTORY. THESE NARROW THOROUGHFARES ARE FOUND THE WORLD OVER AND ARE AS OLD AS HUMANKIND ITSELF. view more 

CREDIT: LARS JOHANSSON

Human history and cultural heritage in various places are often well researched and documented.

A new anthology edited by three Swedish researchers explores what ties these places together – footpaths.

“They are unobtrusive remains, but with a very significant cultural footprint,” says Daniel Svensson, historian at Malmö University.

Pathways lead us forward as we walk along them and also take us back in history. These narrow thoroughfares are found the world over and are as old as humankind itself. But they are only preserved while they remain in use.

“Look but don’t touch is often the name of the game in museums that depict history or cultural heritage. But with pathways it’s the other way around: as long as we keep walking along these remains, they will still be there. Movement becomes part of a living cultural heritage,” says Daniel Svensson.

In the recently published anthology titled Pathways: Exploring the Roots of a Movement Heritage, Daniel Svensson has worked with Katarina Saltzman from the University of Gothenburg, and Sverker Sörlin from the KTH Royal Institute of Technology, to gather texts that describe pathways from a range of perspectives. 15 researchers from countries including India, Israel and the UK have provided a broad range, which has been divided into three parts with history, storytelling and cultural heritage as their themes.

Intangible pathways and cow paths

Although pathways are often overlooked, there is research that has examined pathways as historical remains. There are church paths and school paths as testaments to old patterns of movement in daily life, and coexistence with animals in a past agrarian society can be seen in cow paths that were also used by people. The book includes a chapter that looks at the old English Rights of Way. These rights have also been enshrined in written law, where a pathway that has been used for more than 20 years is considered to be public.

“In another chapter, pathways high in high alpine terrain function as an exhibition space along a mountain pass on the Austrian/Italian border which was a scene of battle in the First World War,” says Daniel Svensson.

The storytelling part of the book draws on examples from pilgrim trails where stories and legends about what happened to the pilgrims live on. There are also descriptions of entirely intangible pathways in computer games. In the early versions of the Zelda computer game, you had to take a certain pathway to progress in the game. Modern computer game worlds are often very extensive, and it can be hard to get an overview of them; players choose to navigate and move between important locations using pathways that they create in those worlds.

“The cultural heritage section in the book is where we bring something new to the table. We have a great amount of material cultural heritage, but pathways remain overlooked. Just as an old building in Gothenburg is important cultural heritage to many, so too can the 8 km trail in Skatås be cultural heritage to those who like to run along it. The movement itself becomes a form of cultural heritage,” says Sverker Sörlin, intellectual historian at KTH Royal Institute of Technology.

Rising value

When the editors requested articles for inclusion in the anthology, there were many researchers who felt called on to write something. According to the editors, pathways are being valued more and more.

Many of the farms in the Forest of the Finns region in northern Värmland have been preserved, but the pathways that ran between them were at risk of falling into oblivion after roads for cars took over as the transport routes. Now some of the old pathways have been selected for inclusion in the hiking trails found there.

“Pathways are living traces of the past. As new pathways come into being while others disappear, we often continue to tread where others have gone before us. Nevertheless, pathways have rarely been regarded as valuable cultural heritage, possibly because they are so discreet and impermanent,” says Katarina Saltzman, ethnologist and landscape researcher at the University of Gothenburg.

Pathways will remain in the future, but their use may change. We have started cycling on pathways when the mountains above the treeline.

“It’s difficult to preserve pathways for the future in a static state because they have to be used. If their use changes, then so does the pathway,” says Daniel Svensson.

The antology´s cover.

CREDIT

White horse press

Self-reported Illness Experiences and Psychosocial Outcomes for Reservation-Area American Indian Youth During COVID-19

JAMA Netw Open. 2022;5(9):e2231764. doi:10.1001/jamanetworkopen.2022.31764

Original Investigation 
Infectious Diseases
September 14, 2022
Key Points

Question  How did American Indian youth who live on or near reservations experience the COVID-19 pandemic?

Findings  This cross-sectional study among 2559 American Indian students in grades 6 through 12 found that approximately 14% of the sample reported having had a test result positive for SARS-CoV-2 infection, a higher rate than for all cases nationally and for children nationally, and three-quarters of the sample reported someone close contracting COVID-19, while more than one-quarter reported someone close dying from COVID-19. Regarding perceived psychosocial impacts, COVID-19 was associated with strained friend relationships, lower school engagement, and less social connectedness, although more than 60% of students reported feeling no change or a decrease in negative emotions, such as sadness and anxiety.

Meaning  These findings suggest that although COVID-19 mortality and morbidity rates were high on American Indian reservations, psychosocial impacts were complex and many students were resilient in the face of the pandemic.

Abstract

Importance  Impacts of COVID-19 on reservation-area American Indian youth are unknown and may be substantial owing to the significant COVID-19 morbidity and mortality experienced by American Indian populations.

Objective  To measure self-reported illness experiences and changes in psychosocial factors during the COVID-19 pandemic among reservation-area American Indian youth.

Design, Setting, and Participants  This cross-sectional study included a random sample of US schools on or near US Indian reservations during Spring 2021, stratified by region, with students in grades 6 to 12 completing cross-sectional online surveys. All enrolled self-identifying American Indian students in grades 6 to 12 attending the 20 participating schools were eligible to be surveyed; participants represented 60.4% of eligible students in these schools. Data were analyzed from January 5 to July 15, 2022.

Exposures  Onset of the COVID-19 pandemic.

Main Outcomes and Measures  Outcomes of interest were COVID-19 self-reported illness outcomes for self and family and close friends; perceived changes in family and friend relationships, school engagement, social isolation, and other psychological factors since the COVID-19 pandemic began; and worry over COVID-19–related health outcomes.

Results  A total of 2559 American Indian students (1201 [46.9%] male; 1284 [50.2%] female; 70 [2.7%] another gender; mean [SD] 14.7 [8.9] years) were included in the analysis. Approximately 14% of the sample reported having had a test result positive for SARS-CoV-2 infection (14.3% [95% CI, 11.4%-17.6%]), a higher rate than for all cases nationally at the time of the survey. Regarding prevalence of COVID-19 among family and close friends, 75.4% (95% CI, 68.8%-80.9%) of participants reported having at least 1 family member or friend who had contracted COVID-19, while 27.9% (95% CI, 18.8%-39.3%) of participants reported that at least 1 family member or close friend had died of COVID-19. Regarding psychosocial impacts, COVID-19 was associated with strained friend relationships (eg, 34.0% [95% CI, 28.4%-40.0%] of students reported worry over losing friends), lower school engagement, and less social connectedness (eg, 62.2% [95% CI, 56.7%-67.4%] of students reported feeling less socially connected to people), although more than 60% of students also reported feeling no change or a decrease in negative emotions. Males were less likely to report perceived negative impacts, especially for negative emotions such as sadness (29.2% [95% CI, 23.3%-35.9%] of males vs 46.1% [95% CI, 43.9%-48.3%] of females reported feeling more sad) and anxiety (21.8% [95% CI, 18.2%-25.8%] of males vs 39.2% [95% CI, 34.1%-44.6%] of females reported feeling more anxious).

Conclusions and Relevance  This cross-sectional study provides novel insight into the perceived experiences of reservation-area American Indian youth, a population at uniquely elevated risk of poor health status and health care access, during the COVID-19 pandemic. Although mortality and morbidity rates from COVID-19 were high on American Indian reservations, student reports of psychosocial impacts were complex and suggest many students were resilient in the face of the pandemic. These findings could be used to understand and address the challenges facing American Indian youth due to the pandemic and to guide future research that examines the factors and processes associated with the reported outcomes.

READ ON

 Self-reported Illness Experiences and Psychosocial Outcomes for Reservation-Area American Indian Youth During COVID-19 | Adolescent Medicine | JAMA Network Open | JAMA Network

For the first time we can measure the thickness of Arctic sea ice all year round

Peer-Reviewed Publication

UIT THE ARCTIC UNIVERSITY OF NORWAY

Melting sea ice in the Arctic 

IMAGE: THE IMAGE SHOWS MELTING SEA ICE IN THE ARCTIC PHOTOGRAPHED FROM THE ALFRED WEGENER INSTITUTE’S AIRBORNE SEA-ICE SURVEY ICEBIRD. view more 

CREDIT: ALFRED-WEGENER-INSTITUTE / ESTHER HORVATH

Using satellites, we are now able to measure the ice thickness – also in the summer. This is of great importance for the shipping in Arctic and future weather and climate forecasts. The solution is developed by an international team, led by researchers at UiT The Arctic University of Norway and the University of Bristol. 

"The Arctic ice is melting faster than ever. We need knowledge about the thickness of the sea ice, both to reduce safety risks for businesses and shipping in the Arctic, but also to make forecasts for the future climate," says team leader Jack Landy at the Department of Physics and Technology at UiT who began the work while at the University of Bristol.

The research team has developed the first dataset showing the thickness of sea ice across the entire Arctic and through a whole year. The results are published in the journal Nature.

Satellites are dazzled by the melting ice

Satellites have been used to measure the thickness of ice in the Arctic since the 1980s. But the technique has only worked in winter, from October to March, when the ice and snow are cold and dry.

"In the summer months the satellites are dazzled by ponds of snow and ice meltwater that pool on the sea ice surface. Then they have been unable to distinguish between melting ice and water," says Landy.

Using AI to solve the problem

To solve the problem, the researchers have adopted Artificial Intelligence (AI) and examined previous data from the satellites. Now they know when the satellites register ice and when they register ocean.

In addition, the team has constructed a new computer model of the satellite sensor, to make sure it is measuring the correct height and thickness.

This is good news for the shipping industry.

Safer to sail in Arctic waters

Shipping in the Arctic has increased rapidly in recent years, because of the ice melting. Particularly in the Barents Sea and close to Svalbard the shipping activity is high during summer. To sail safely, the boats need information about where there is ice and how thick it is, in advance.

The Norwegian Meteorological Institute provide sea ice forecasts for the Arctic but have lacked secure ice thickness data for the summer months.

“Using the new satellite data, we are finally able to make sea ice forecasts informed by the ice thickness, not only for the winter, but also for the summer. This will reduce safety risks for ships and fishing boats," says Landy.

"We can also predict whether there will be ice or not at a given location in September, by measuring the ice thickness in May," he says.

Increased understanding of the climate 

According to Associate Professor Dr Michel Tsamados from University College London the findings are also of great importance for our understanding of the weather and the climate.

He is one of the researchers behind the study and explains that the new data can be used in advanced climate models to improve our weather and climate forecasts.

– When we use the new ice thickness data in advanced climate models, it will improve both our short-term forecasts for the weather at the mid-latitudes and the long-term forecasts that show what climate we will have in the future," he says.

It’s a planet: new evidence of baby planet in the making

Peer-Reviewed Publication

HARVARD-SMITHSONIAN CENTER FOR ASTROPHYSICS

Planet Discovered in System LkCa 15 

IMAGE: ARTIST’S ILLUSTRATION OF A SMALL SATURN-LIKE PLANET DISCOVERED IN THE SYSTEM LKCA 15. THE PLANET RESIDES WITHIN DENSE RINGS OF DUST AND GAS THAT SURROUND A BRIGHT YELLOW STAR. MATERIAL ACCUMULATES IN A CLUMP AND ARC-SHAPE, ABOUT 60 DEGREES AWAY FROM THE PLANET. NOTE: THIS ILLUSTRATION IS NOT TO SCALE. view more 

CREDIT: M.WEISS/CENTER FOR ASTROPHYSICS | HARVARD & SMITHSONIAN

Cambridge, Mass. – Astronomers agree that planets are born in protoplanetary disks — rings of dust and gas that surround young, newborn stars. While hundreds of these disks have been spotted throughout the universe, observations of actual planetary birth and formation have proved difficult within these environments.

Now, astronomers at the Center for Astrophysics | Harvard & Smithsonian have developed a new way to detect these elusive newborn planets — and with it, “smoking gun” evidence of a small Neptune or Saturn-like planet lurking in a disk. The results are described today in The Astrophysical Journal Letters

“Directly detecting young planets is very challenging and has so far only been successful in one or two cases,” says Feng Long, a postdoctoral fellow at the Center for Astrophysics who led the new study. “The planets are always too faint for us to see because they’re embedded in thick layers of gas and dust.”

Scientists instead must hunt for clues to infer a planet is developing beneath the dust. 

“In the past few years, we’ve seen many structures pop up on disks that we think are caused by a planet’s presence, but it could be caused by something else, too” Long says. “We need new techniques to look at and support that a planet is there.”

For her study, Long decided to re-examine a protoplanetary disk known as LkCa 15. Located 518 light years away, the disk sits in the Taurus constellation on the sky. Scientists previously reported evidence for planet formation in the disk using observations with the ALMA Observatory.

Long dove into new high-resolution ALMA data on LkCa 15, obtained primarily in 2019, and discovered two faint features that had not previously been detected.

About 42 astronomical units out from the star — or 42 times the distance Earth is from the Sun — Long discovered a dusty ring with two separate and bright bunches of material orbiting within it. The material took the shape of a small clump and a larger arc, and were separated by 120 degrees. 

Long examined the scenario with computer models to figure out what was causing the buildup of material and learned that their size and locations matched the model for the presence of a planet. 

“This arc and clump are separated by about 120 degrees,” she says. “That degree of separation doesn’t just happen — it’s important mathematically.”

Long points to positions in space known as Lagrange points, where two bodies in motion — such as a star and orbiting planet — produce enhanced regions of attraction around them where matter may accumulate.  

“We’re seeing that this material is not just floating around freely, it’s stable and has a preference where it wants to be located based on physics and the objects involved,” Long explains.  

In this case, the arc and clump of material Long detected are located at the L4 and L5 Lagrange points. Hidden 60 degrees between them is a small planet causing the accumulation of dust at points L4 and L5.

The results show the planet is roughly the size of Neptune or Saturn, and around one to three million years old. (That’s relatively young when it comes to planets.) 

Directly imaging the small, newborn planet may not be possible any time soon due to technology constraints, but Long believes further ALMA observations of LkCa 15 can provide additional evidence supporting her planetary discovery. 

She also hopes her new approach for detecting planets — with material preferentially accumulating at Lagrange points — will be utilized in the future by astronomers. 

“I do hope this method can be widely adopted in the future,” she says. “The only caveat is that this requires very deep data as the signal is weak.”

Long recently completed her postdoctoral fellowship at the Center for Astrophysics and will join the University of Arizona as a NASA Hubble Fellow this September.  

Co-authors on the study are Sean Andrews, Chunhua Qi, David Wilner and Karin Oberg of the CfA; Shangjia Zhang and Zhaohuan Zhu of the University of Nevada; Myriam Benisty of the University of Grenoble; Stefano Facchini of the University of Milan; Andrea Isella of Rice University; Jaehan Bae of the University of Florida; Jane Huang of the University of Michigan and Ryan Loomis of the National Radio Astronomy Observatory. 

The team used high resolution ALMA observations taken with Band 6 (1.3mm) and Band 7 (0.88mm) receivers. 

###

About the Center for Astrophysics | Harvard & Smithsonian

The Center for Astrophysics | Harvard & Smithsonian is a collaboration between Harvard and the Smithsonian designed to ask—and ultimately answer—humanity's greatest unresolved questions about the nature of the universe. The Center for Astrophysics is headquartered in Cambridge, MA, with research facilities across the U.S. and around the world.

University of Ottawa's Faculty of Medicine team reveals underpinnings of how motor memory forms

In a study published this week in Neuron, a research team led by Dr. Simon Chen of the University of Ottawa's Faculty of Medicine offers new and valuable insights into an enduring mystery of neuroscience.

Peer-Reviewed Publication

UNIVERSITY OF OTTAWA

Dr. Simon Chen, Canada Research Chair in Neural Circuits and Behaviour from the University of Ottawa 

IMAGE: “IF WE UNDERSTAND HOW THE ACQUISITION OF MOTOR SKILLS IS REGULATED IN THE BRAIN THEN PERHAPS ONE DAY WE CAN HELP PATIENTS WITH STROKE OR PARKINSON’S DISEASE REGAIN THOSE SKILLS DURING THE REHABILITATION PROCESS." view more 

CREDIT: UNIVERSITY OF OTTAWA

When you are first learning how to ride a bicycle or play a musical instrument, your physical movements are uncoordinated at best. But with time and lots of repetition, your brain’s motor neurons create a kind of shorthand between mind and muscle. The associated motions eventually become so ingrained that jumping on a bike or playing scales feels nearly automatic.

What are the cellular underpinnings of how this motor learning process works? In a study published this week in Neuron, a research team led by Dr. Simon Chen of the uOttawa Faculty of Medicine offers new and valuable insights into this enduring mystery of neuroscience.

His lab is focused on unraveling how memories are encoded and stored in the brain, particularly with motor learning, the complex process of how we move and coordinate the muscles of our bodies. With this latest study, Dr. Chen’s research team explored the mechanisms involved in regulating the process of motor memory acquisition and consolidation during repetitive practice.

Dr. Chen, Canada Research Chair in Neural Circuits and Behaviour, says the study’s findings could prove useful for developing therapeutic targets that can help recover motor functions in patients suffering from Parkinson’s disease, a stroke or a brain injury. This is significant because restoring gross motor coordination and regaining lost movements is a very difficult battle for these individuals.

“If we understand how the acquisition of motor skills is regulated in the brain then perhaps one day we can help patients with stroke or Parkinson’s disease regain those skills during the rehabilitation process,” he says.

The study focused on mice, not people. But since scientists believe that the mechanisms of memory formation are very similar in mice and human beings, the findings likely have deep relevance for people.

So how did the experiments work?

By restricting the head movements of mice on the imaging stage, which allows scientists to probe the brain at single-cell resolution, the team trained the animals to perform a specific motor task: Reach and grasp a food pellet from a motorized delivery holder.

Initially, the head-restrained mice were tentative and clumsy when grabbing the pellet. The researchers conducted detailed analysis of the animals’ movements using DeepLabCut, a deep-learning software toolbox combining motion-capture video with artificial intelligence. They found that with repetition and time, mice formed stereotyped reach-and-grasp movements that allowed them to eventually secure the food easily.

The team wanted to see the activation of neurons specific to these reach-and-grasp movements—and view the formation of synaptic pathways in the brain as they occurred.

“We were able to monitor the brain changes while mice were actually learning this task,” says Dr. Chen, an associate professor at the Faculty of Medicine’s department of Cellular and Molecular Medicine.

Using two-photon imaging, a type of microscopy that permits the visualization of living tissue at micrometer scale, his team was able to view the reorganization of dendritic spines among the excitatory neurons in the primary motor cortex as the head-fixed mice performed these pellet-grabbing actions over time. Dendritic spines—neural structures at synapses resembling lollipops with skinny sticks and bubble-like tops—are key for memory formation and storage.

Zooming in to the cellular level, the researchers discovered that motor learning selectively induces the expression of an activity-dependent “transcription factor” called NPAS4 in the primary motor cortex.

What these novel findings unveil, says Dr. Chen, is that the expression of this transcription factor triggers the emergence of a learning-associated inhibitory neuron ensemble that modulates inhibition in the primary motor cortex. That regulates the dendritic spine reorganization process among excitatory neurons during learning.

Essentially, NPAS4 regulates the gene changes in the inhibitory neurons that control the activity of these neurons similar to the way a volume slider controls a laptop’s speakers. Dr. Chen says these findings “also demonstrate that inhibitory neuron-specific induction of a transcription factor acts as a defining feature underlying the formation of neuronal ensembles engaged by an act of learning.”

In other words, repeating the movements over time changed the inner workings of the animals’ primary motor cortex – the part of the brain that only mammals possess, and which controls complex movements.

The team found that the expression of the NPAS4 transcription factor in inhibitory neurons is key to how your brain winnows down options to form the strongest motor memories for specific movements – and it needs to be consistently re-expressed for those memories to get lodged and refined in your brain while doing repetitive practices.

Can the brain recover after boxers, MMA fighters stop fighting?


Peer-Reviewed Publication

AMERICAN ACADEMY OF NEUROLOGY

MINNEAPOLIS – Boxers and mixed martial arts (MMA) fighters may see some recovery in their thinking and memory skills as well as brain structure after they stop fighting, according to a new study published in the September 14, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

“Repetitive hits to the head increase the risk of long-term neurologic conditions like chronic traumatic encephalopathy (CTE), cognitive and behavior problems and parkinsonism,” said study author Aaron Ritter, MD, of Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas, Nevada. “However, we haven’t known what happens to people who have been fighting and then stop fighting. The good news is we saw some improvement in thinking and memory scores in these retired fighters.”

For the study, researchers identified 45 male retired fighters who had not competed in two years, with an average age of 32, including 22 boxers, 22 MMA fighters and one martial artist. They also identified 45 male active fighters, with an average age of 30, including 17 boxers, 27 mixed martial artists and one martial artist. The groups were matched for age, education, race, and number of fights at the beginning of the study.

All fighters had a professional fight within a year of the start of the study. However, retired fighters then went two years without any fights while active fighters continued to participate in professional fights.

Over three years, all fighters had brain scans and completed tests to see how well their brains were working at the both the beginning and the end of the study. Researchers also looked at participants’ fighting histories. Half of the participants also had blood tests for a biological marker of brain injury called neurofilament light chain, a component of nerve fibers that can be detected in the blood when the fibers are injured.

The participants also took tests to measure verbal memory, executive functioning, motor speed and processing speed.

In the areas of verbal memory, motor speed and processing speed, the retired fighters had improvements in their scores over time, while the active fighters’ scores were stable or showed subtle declines.

For verbal memory, researchers used scores from an FDA approved thinking and behavior test with higher scores indicating better memory. They found that over time, retired fighters on average had an increase of three points whereas active fighters had an average decrease of two points.

Researchers also found different patterns of change over time between retired and active fighters in the ability to detect and respond to rapid changes in the environment and how long it takes to complete tasks.

For neurofilament light chain levels, retired fighters showed a decrease in levels in their blood from the start to the end of the study, while active fighters remained stable throughout the study.

Researchers also measured brain thickness in the areas of the brain that control emotion, memory, and executive function, which is a person’s ability to plan, focus, and manage multiple tasks. Out of 68 brain regions measured, 54 regions had a consistently changing trajectory, with thickness measures stabilizing for retired fighters and subtly declining over time for active fighters.

“The results of this study suggest a recovery of cognitive functioning in fighters who are no longer exposed to repetitive hits to the head,” said Ritter. “Future research is needed to determine if there is a time in a fighter’s career where recovery is less likely to happen or to identify factors that might indicate greater risk for developing a neurodegenerative condition.”

A limitation of the study was the inability to determine the exact number of repetitive head hits each participant sustained. Many head impacts occur during training, and there is no generally accepted way of measuring them. This study also looked only at male fighters.

The study was funded by the National Institutes of Health, Lincy Foundation, Belator, Ultimate Fighting Championship Company (UFC), the August Rapone Family Foundation, Top Rank, and Haymon Boxing.

Learn more about brain health at BrainandLife.org, home of the American Academy of Neurology’s free patient and caregiver magazine focused on the intersection of neurologic disease and brain health. Follow Brain & Life® on FacebookTwitter and Instagram.

When posting to social media channels about this research, we encourage you to use the hashtags #Neurology and #AANscience.

The American Academy of Neurology is the world’s largest association of neurologists and neuroscience professionals, with over 38,000 members. The AAN is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, concussion, Parkinson’s disease and epilepsy.

For more information about the American Academy of Neurology, visit AAN.com or find us on FacebookTwitterInstagramLinkedIn and YouTube.