Monday, April 17, 2023

Over 1 million lives saved across Europe by COVID-19 vaccines since the end of 2020

New research shows that 96% of all lives saved were in adults aged 60 and older

Reports and Proceedings

EUROPEAN SOCIETY OF CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASES

**Note: the release below is from the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023, Copenhagen, 15-18 April)Please credit the conference if you use this story**

COVID-19 vaccination directly saved at least 1,004,927 lives across Europe between December 2020 and March 2023, according to new research being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April).

The new estimates by WHO/Europe and presented at the conference by Dr Margaux Meslé,  Epidemiologist at WHO/Europe highlight the striking impact of COVID-19 vaccine programmes and also underscore the urgent need for countries with low vaccination coverage to fully vaccinate their older adults.

Since the emergence and subsequent spread of SARS-CoV-2 in early 2020, over 2 million COVID-19 laboratory-confirmed deaths have been officially recorded by WHO/Europe.

Countries in the WHO European Region (which includes all countries in the European Union and European Economic Area) have introduced COVID-19 vaccine programmes to protect vulnerable groups from severe disease with several waves of variants of concern (VOC).

The authors used weekly reported deaths and vaccination doses by 26 countries and areas to WHO/Europe and the European Centre for Disease prevention and Control between December 2020 and March 2023, to calculate the number of lives saved by vaccination dose, VOC period, age group (25 to 49 years, 50 to 59 years and 60 years or older) and country.

Vaccine effectiveness was considered in the context of each dominant VOC period.

The new estimates suggest that the majority (96%) of the lives saved were in people aged 60 years and older.

In this older age group, the first booster saved the most lives, accounting for almost two-thirds (64%) of lives saved.

Overall, across all age groups and countries, vaccines are estimated to have saved the largest number of lives during the Omicron wave, with at least 568,064 deaths prevented. This represents over half (57%) of the lives saved.

This research did not consider the indirect effects of vaccinations, differing healthcare capacities between countries and non-pharmaceutical interventions.

“We see from our research, the large numbers of lives saved by COVID-19 vaccines across Europe during the pandemic. However, too many people in vulnerable groups across the WHO European Region remain unvaccinated or partially vaccinated. We urge people who are eligible and who have not yet taken the vaccine to do so," says Dr Richard Pebody, Head of the High Threat Pathogen Team at WHO/Europe.

Notes to editors:

The authors declare no conflicts of interest.

This press release is based on abstract 01898 at the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) annual meeting. The material has been peer reviewed by the congress selection committee. There is no full paper available at this stage, and the work has not yet been submitted to a medical journal for publication.

For full abstract click here


Coronavirus

CREDIT

PD

Beyond the Virus: Multidisciplinary and International Perspectives on Inequalities Raised by COVID-19


In their new book, The City Law School’s Dr Sabrina Germain and Dr Adrienne Yong explore social inequalities brought to the fore by the COVID-19 public health crisis

Book Announcement

CITY UNIVERSITY LONDON

Dr Adrienne Yong and Dr Sabrina Germain with their book 

IMAGE: DR ADRIENNE YONG AND DR SABRINA GERMAIN WITH THEIR BOOK view more 

CREDIT: DR ADRIENNE YONG AND DR SABRINA GERMAIN

The below are excerpts taken from the Introduction – Perspectives on Power, Gender and Marginalization, by Germain SYong A (eds) Beyond the Virus: Multidisciplinary and International Perspectives on Inequalities raised by COVID-19 (Bristol University Press, 2023).

During 2020, the COVID-19 pandemic took hold globally, claiming countless lives, yet more widely throwing everyday life into disarray for countless more. As the pandemic unfolded, it became more and more obvious that whilst everyone was susceptible to contracting the virus, there were stark social inequalities being brought to the fore in many areas outside simply direct health consequences. The topic of COVID-19 became central to many research areas in a multitude of different disciplines across the world, leading to an explosion of scholarship, mainly reactionary pieces of research published in response to the developments occurring in real time, leaving a gap in the literature for a broader reflection on what has happened since COVID-19 was declared a pandemic in early 2020.

Our own contribution to the COVID-19 scholarship was added in October 2020 in this way, through a co-authored journal article that brought together both of our expertise in health law, race and gender issues and migration from a feminist perspective in the context of the pandemic. It outlined our emerging research on the disproportionate impact on women possessing certain intersectional characteristics, centring on the barriers to accessing healthcare. However, the increasing amount of COVID-19 scholarship began to demonstrate that experts in the fields of law, policy and other humanities were interested in studying the diverse impact of the pandemic on populations in their specific fields, but had yet to take a multidisciplinary approach to understanding how the phenomenon has deepened existing inequalities outside direct health consequences. It was from this premise that the idea for the edited collection was born, having realised that the inequalities raised by the pandemic pervaded all areas of society and worldwide.

Streams of Inequality

Beyond the Virus has provided us with an opportunity to fill a significant gap in the literature, with its carefully crafted array of chapters from multiple disciplines and international experts who are proudly from a variety of different backgrounds. The originality in this volume is thus its consideration of these issues in relation to the pandemic, focusing on thematic strands to gain a greater understanding of these underlying problems, including how the law, or absence of it, has exacerbated inequalities. We identified three strands in particular that emerged from considering inequalities beyond just the virus itself: on power and governance, on gender, and for marginalised communities. It is under these three themes that this collection uncovers how unequal the pandemic truly is.

The first section on power and governance seeks to interrogate whether the State has taken into account external factors in their governance of the COVID-19 public health crisis beyond just the medical aspects of the virus. The second section on gender seeks to investigate how gender inequalities have been forgotten in the imposition of and messaging around accommodations made to curb the spread of the virus. The third section on marginalised communities seeks to give voice to groups of vulnerable individuals and understand whether during the pandemic they have become more sidelined because of the prioritisation of the public health crisis.

Diverse perspectives

Diversity was considered in all of our chapters and contributors in various forms. It was in the sense of seniority in the academy, with our collection including doctoral scholars and early career researchers alongside mid-career researchers and Professors. It was in the context of a balance of genders and ethnicities, both in terms of the subject matter of chapters themselves as well as the identities of the authors themselves contributing to the volume. Diversity was also considered geographically. The collection does not solely focus on a Western nor single national perspective. We sought to represent both the Global North and the Global South in areas of the world which the pandemic has drawn attention to, demanding a more critical evaluation of countries in the spotlight of global media. The intersectional nature of a number of the issues was also salient and a key factor. Finally, diversity was also important to us in terms of methodologies and disciplinary approaches. This was especially necessary given the pandemic’s ubiquity. We drew from politics, sociology, culture and media and journalism to enrich our exploration of issues beyond just the law in order to provide a unique outlook on the pandemic domestically, internationally and globally.

These inequalities have long existed without sufficient political attention and are questions that are now more urgent due to the widespread global effects of the pandemic. They are complex questions requiring a multi-layered approach and a more focused and in-depth analysis. With its explicit focus on promotion of diversity as seen through the international and multidisciplinary approaches taken by the range of chapter contributors, this collection can critically assess how the COVID-19 pandemic has had an effect on social inequalities in the context of the three streams, with the specific intention of looking beyond the virus, and towards many other areas of inequalities that has hit so many so hard.

Contributors to the edited collections are as follows:

· Buhm-Suk Baek, Professor of Public International Law, Kyung Hee University (South Korea).

· Louise Bernier, Professor in Health Law & Bioethics, Law Faculty, Université de Sherbrooke (Canada).

· Gwilym David Blunt, Senior Research Fellow at the Centre for International Policy Studies, City, University of London.

· Julia Boelle, PhD graduate of Cardiff University’s School of Journalism, Media and Culture.

· Mylaine Breton, Professor in the Department of Social Science and Medicine, Université de Sherbrooke (Canada).

· Valentina Cardo, Associate Professor of Politics and Identity, Winchester School of Art, University of Southampton.

· Y.Y. Brandon Chen, Assistant Professor, Faculty of Law Faculty, University of Ottawa (Canada).

· Marie-Ève Couture Ménard, Professor at the Faculty of Law Faculty, Université de Sherbrooke (Canada).

· Jean-Frédéric Ménard, Assistant Professor, Faculty of Law, Université de Sherbrooke (Canada).

· Naomi Finch, Lecturer in Social Policy, Department of Social Policy and Social Work, University of York.

· Roy Gilbar, Professor in the School of Law, Netanya Academic College (Israel).

· Simon Halliday, Professor in Socio-Legal Studies, York Law School, University of York.

· Nili Karako-Eyal, Senior Lecturer, Haim Striks School of Law College of Management (Israel).

· Jed Meers, Lecturer in Law, York Law School, University of York.

· Natalia Pires de Vasconcelos, Assistant Professor of Law, Insper Instituto de Ensino e Pesquisa (Brazil).

· Joe Tomlinson, Professor in Public Law, York Law School, University of York.

· Mark Wilberforce, Senior Research Fellow, Social Policy Research Unit, University of York.

Ends

Two years of patient data reveal real-world efficacy of COVID-19 treatments


Peer-Reviewed Publication

UNIVERSITY OF PITTSBURGH

Kevin Kip, Ph.D. 

IMAGE: KEVIN KIP, PH.D., VICE PRESIDENT OF CLINICAL ANALYTICS AT UPMC view more 

CREDIT: KEVIN KIP

PITTSBURGH, April 3, 2023 – The COVID-19 pandemic created a real-life experiment that demanded health care providers nationwide rapidly stand up clinics to administer an evolving offering of monoclonal antibody treatments that — while initially proven safe and effective in clinical trials and approved under federal emergency use authorization — had never been tested at such a scale.

The task was massive and the real-world benefit uncertain, particularly for monoclonals approved later in the pandemic based only on laboratory data. An analysis published today in the Annals of Internal Medicine by UPMC and University of Pittsburgh School of Medicine clinicians and scientists shows that it was worth it.

“The virus was a moving target, and, for two years, monoclonal antibodies were approved, revoked, sometimes reauthorized and sometimes scarce,” said lead author Kevin Kip, Ph.D., vice president of clinical analytics at UPMC. “Using UPMC’s database of patients treated with monoclonal antibodies —one of the largest in the U.S. — we are finally able to conclude that pushing through all these challenges unequivocally saved lives and prevented hospitalizations.”

Monoclonal antibodies are human-made antibodies specifically designed to prevent a pathogen — in this case the virus that causes COVID-19 — from entering human cells, replicating and causing serious illness. The U.S. Food and Drug Administration granted emergency use authorization to five different COVID-19 monoclonal antibody treatments at various times between 2020 and 2022. All were restricted to people age 12 and older with risk factors that made them more susceptible to bad outcomes from COVID-19. The treatments had to be administered intravenously or through injection by a health care professional. As the virus evolved, new monoclonal antibodies were introduced and older ones, which were no longer effective, were removed.

Starting with the first authorization at the end of 2020, UPMC opened dozens of clinics, set up emergency department infrastructure and arranged home visits to maximize its ability to provide monoclonal antibodies to patients in Pennsylvania, New York and Maryland. After the emergency use authorization was revoked for the last monoclonal antibody on Nov. 30, 2022, and no new monoclonal antibodies were introduced, UPMC pulled anonymous clinical data on 2,571 patients treated with monoclonal antibodies and matched them with data from 5,135 patients with COVID-19 who were eligible for monoclonal antibodies but did not receive them.

On average, people who received monoclonal antibodies within two days of a positive COVID-19 test reduced their risk of hospitalization or death by 39% compared to their peers who did not receive the treatment. Patients with immunocompromising conditions, regardless of their age, had an even greater reduced risk.

Patients treated when the alpha and delta variants of the virus were circulating experienced greater benefit than their untreated peers compared to those treated when the omicron variant was circulating, likely because earlier variants were more deadly and people had less prior immunity from previous infection or vaccination. By the time omicron was circulating, risk of death and hospitalization had fallen in general, so monoclonal antibody treatment had less overall benefit, but still clinically meaningful benefit, particularly in vulnerable patients, explained co-author Erin McCreary, Pharm.D., director of infectious diseases improvement and clinical research innovation at UPMC.

“Right now, COVID-19 has a relatively low risk of death for the general population, but we have seen how quickly this virus can mutate and spread. Nobody can say with certainty that a future variant won’t be more deadly,” McCreary said. “Should that happen, our real-world data give reassurance that investing in the infrastructure and health care worker knowledge to quickly give antibody treatments keeps people in the communities we serve alive and out of the hospital.”

Additional authors on this research are Kevin Collins, M.B.A., Tami E. Minnier, M.S., Graham M. Snyder, M.D., M.S., William Garrard, Ph.D., Jeffrey C. McKibben, M.S., Donald M. Yealy, M.D., Christopher W. Seymour, M.D., M.S., David T. Huang, M.D., M.P.H., J. Ryan Bariola, M.D., Mark Schmidhofer, M.D., Richard J. Wadas, M.D., Derek C. Angus, M.D., M.P.H., Paula L. Kip, Ph.D., and Oscar C. Marroquin, M.D., all of UPMC, Pitt or both.

Lower risk of severe illness and death in newborns of low-income immigrant than Canadian-born females

Peer-Reviewed Publication

CANADIAN MEDICAL ASSOCIATION JOURNAL

Newborns of non-refugee immigrant females are at overall lower risk of serious illness and death than those of Canadian-born females in low-income neighbourhoods in Ontario, according to new research published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221711.

Previous research has looked at the risk of adverse outcomes for newborns in low- v. high-income neighbourhoods, but there is little evidence on the respective risks for immigrant and nonimmigrant mothers living in similar low-income neighbourhoods. Both immigration status and living in a low-income neighbourhood have been associated with poorer neonatal outcomes.

To understand the risk of severe neonatal morbidity and mortality (SNMM) in infants born to immigrants compared with nonimmigrants, researchers looked at data on all live, in-hospital births of single babies (singleton) at 20–42 weeks' gestation between 2002 and 2019 in Ontario. Ontario, Canada's largest province, receives about 53% of female immigrants entering the country.

Indicators of severe neonatal morbidity included breathing support, intravenous fluid use, early birth (before 32 weeks' gestation), very low birth weight and respiratory distress.

During the study period, there were 414 241 singleton births to 312 124 females aged 15 years and older living in low-income urban neighbourhoods. Of live births, 148 050 were to immigrants and 266 191 to Canadian-born females. The risk of SNMM for newborns of immigrant females was significantly lower than for newborns of Canadian-born females (49.7 per 1000 live births compared with 65.6 per 1000 live births). However, risk varied depending on the country of origin, with a higher risk of SNMM in newborns of immigrants from Jamaica and Ghana and in those with longer residence in Ontario.

The Healthy Immigrant Effect may explain some of these differences.

"Immigrant females who are healthier and more resilient may be most capable of migration; the immigration policy of a host country may preferentially select healthy immigrants," writes Dr. Joel Ray, a physician at St. Michael's Hospital, a site of Unity Health, and scientist at ICES, with coauthors.

"Another explanation may be that some immigrants have greater net income, educational achievement and health literacy than the average for a low-income neighbourhood," adds Dr. Patricia O'Campo, co-author and epidemiologist, St. Michael's Hospital and the University of Toronto, Toronto, Ontario.

The research underscores the importance of looking at trends at neighbourhood levels and that there is variability within areas.                                                                                                 

"Efforts should be aimed at improving the overall health and well-being of all females residing in low-income areas, and at determining if the risk of adverse birth outcomes can be equitably reduced among immigrant and nonimmigrant groups," concludes Jennifer Jairam, a PhD candidate from the University of Toronto.

Come health or high water

Historically oppressed communities are faced with compounded health, economic and social injustices – with climate change making them worse.

Grant and Award Announcement

UNIVERSITY OF PITTSBURGH

Pitt engineers joined an interdisciplinary team and received $1.35 million from the United States Environmental Protection Agency (US EPA) to study the impact of climate change on behavioral and respiratory effects of fungal and bacterial pathogens on Black Americans living in the Homewood and Hill District neighborhoods of Pittsburgh. Sarah Haig, Assistant Professor of Civil and Environmental Engineering and co-investigator on the project, and her lab will collect dust samples from 110 Pittsburgh households to determine what’s possibly lurking in their basements. 

“Interactions between changing precipitation patterns and indoor air quality in urban-built environments are still poorly understood and have little research behind them,” said Haig. “By studying the presence and abundance of pathogenic respiratory fungi and bacteria found in basement dust we can begin to understand how climate change impacts home dampness and in turn how this impacts the air we breathe whilst indoors..” 

Rainfall, especially in the northeast United States, is increasing in frequency and intensity. These shifts in precipitation patterns are linked to flash flooding and even wetter basements. A wet basement creates weakened infrastructure, putting households at risk of exposure to environmental contaminants through leaks, breaks and sewer backups. 

“Our hope, together as a team, is to document conditions that simply have not been systematically documented, and to understand the impact of changing weather events (specifically extreme rainfall) on households in the Hill District and Homewood – two neighborhoods that have been historically oppressed,” said Tamara Dubowitiz, principal investigator of the project and senior policy researcher at the RAND Corporation. “This is where the environmental justice component comes into play – we recognize the importance of gathering data in order to advocate for change and improvement of conditions in the neighborhoods that all too often are forgotten.” 

These environmental contaminants put residents at risk for asthma, rhinitis, and respiratory conditions, often leading to stress and depression. 

Alyssa Lyon, director of the Black Environment Collective at the UrbanKind Institute and co-investigator, said the environment directly impacts health – especially in marginalized communities. 

“Some of the people I’ve worked with in these areas have recounted their relationship with the environment,” Lyon said. “From having to quit their job because their child has severe asthma and as a result their child not being able to attend school. Due to lack of education, despair, and even confusion – all those collateral consequences – that child could eventually even turn to addiction. I think there’s a direct link between mental health  and a healthy space.” 

Lyon explained that because of the vulnerability of the communities in large-scale research projects, it’s important to include Black-led environmentalist groups to ensure accountability and transparency from the researchers for the residents. 

“It’s important for these institutions to know that we have our eye on you,” she said. “We’re going to make sure this money is going to be used for what you said it was going to be used for: to help these residents.” 

Haig and other researchers on the project are also concerned about radon: an invisible, radioactive and odorless gas that can be present in soil and groundwater. Radon enters a home through its foundation – especially a weakened one. Exposure to radon can cause difficulty breathing and swallowing, a bad cough, a hoarse speaking voice and tightness in the chest. 

Because of the number of homes,Haig and her team will need a little over two years to complete their research. The results will be used to study the link between basement pathogens, basement moisture, daily rainfall extremes, housing and neighborhood conditions, and cumulative health impacts for residents across the adult lifespan. The team is planning on working with local government agencies to develop and disseminate community-based solutions to solve the cumulative health impacts that are caused by these compounding issues.

Walter Lewis, president and CEO of the Homewood Children’s Village and another  principal investigators, said it’s critical that the project prioritizes community-based solutions that build on the research. He added that the project’s focus on community and using research to drive actual change was what led him to become a part of the project team. 

“All researchers are in agreement that this is not just another study that just gets published and sits on a shelf,” Lewis said. “It needs to be a study that turns into action, and there are people in the community also talking about it – using that power to ensure change happens.” 

The project, “Health and High Water: Health Impacts of Increased Rainfall of Families Living in Racially Isolated Neighborhoods in Pittsburgh PA,” also includes: 

  • The University of Pittsburgh: Daniel Bain and Emily Elliott
  • RAND Corporation: Linnea Warren May and Pierrce Holmes
  • Homewood’s Children’s Village: Raymond Robinson, Rebecca McDonough
  • Black Environmental Collective/UrbanKind Institute: Jamil Bey

THIRD WORLD U$A

Poverty is the fourth greatest cause of U.S. deaths, analysis published in JAMA finds.

Only heart disease, cancer and smoking kill more Americans

AND THESE ARE DIRECTLY IMPACTED BY POVERTY

Peer-Reviewed Publication

UNIVERSITY OF CALIFORNIA - RIVERSIDE

David Brady 

IMAGE: DAVID BRADY view more 

CREDIT: UNIVERSITY OF CALIFORNIA, RIVERSIDE

Poverty has long been linked to shorter lives. But just how many deaths in the United States are associated with poverty? The number has been elusive – until now.

UC Riverside paper published Monday in the Journal of the American Medical Association associated poverty with an estimated 183,000 deaths in the United States in 2019 among people 15 years and older. 

This estimate is considered conservative because the data is from the year just prior to the COVID-19 pandemic, which caused spikes in deaths worldwide and continues to take its toll.

The analysis found that only heart disease, cancer, and smoking were associated with a greater number of deaths than poverty. Obesity, diabetes, drug overdoses, suicides, firearms, and homicides, among other common causes of death, were less lethal than poverty. 

“Poverty kills as much as dementia, accidents, stroke, Alzheimer's, and diabetes,” said David Brady, the study’s lead author and a UCR professor of public policy. “Poverty silently killed 10 times as many people as all the homicides in 2019. And yet, homicide firearms and suicide get vastly more attention.” 

Another finding is that people living in poverty – those with incomes less than 50% of the U.S. median income -- have roughly the same survival rates until they hit their 40s, after which they die at significantly higher rates than people with more adequate incomes and resources.

The analysis estimated the number of poverty deaths by analyzing income data kept by the Institute for Social Research at the University of Michigan and death data from household surveys from the Cross-National Equivalent File. Deaths reported in surveys were validated in the National Death Index, a database kept by the National Center for Health Statistics, which tracks deaths and their causes in the U.S.

Their findings have major policy implications, the researchers say.

“Because certain ethnic and racial minority groups are far more likely to be in poverty, our estimates can improve understanding of ethnic and racial inequalities in life expectancy,” the paper reads.

Additionally, the study shows that poverty should get more attention from policymakers, said Brady, the director of UCR’s Blum Initiative on Global and Regional Poverty.

Beyond the emotional suffering of surviving family members and friends, deaths are associated with a great economic cost. Experts agree that a death is expensive for a family, community and government, Brady said.

“If we had less poverty, there'd be a lot better health and well-being, people could work more, and they could be more productive,” Brady said. “All of those are benefits of investing in people through social policies.”

The paper is titled “Novel Estimates of Mortality Associated With Poverty in the US.” In addition to Brady, study authors include Professor Ulrich Kohler at the University of Potsdam, Germany, and Professor Hui Zheng at Ohio State University in Columbus. 
 

Income rank linked to experience of physical pain, irrespective of whether in a rich or poor country, study suggests


New study suggests that comparing one’s earnings relative to peers may induce negative emotions that lead to physical pain

Peer-Reviewed Publication

CITY UNIVERSITY LONDON

A new study of worldwide polling data suggests that a person’s income rank relative to their peers is linked to their experience of physical pain, with a lower income rank linked to a higher likelihood of experiencing pain. It is the first time such a relationship has been shown.

The study found the link to persist, to the same degree, irrespective of whether the person lives in a rich country or a poor country.

Income rank is the position of an individual’s absolute personal income amount in a list of those amounts ordered from lowest to highest.  The higher the position in the list, the higher the income rank.

The study, authored by Dr Lucía Macchia, Lecturer in Psychology at City, University of London, also suggests that people in poor countries fare no better than those living in rich countries when it comes to the effect of the absolute amount of personal income they earn on the likelihood of them experiencing pain. This was an unexpected finding and requires further investigation, as the prediction was that those in poorer countries would be more strongly affected, assuming that an increase in absolute income would allow them to obtain more resources to support their wellbeing that are more readily available in rich countries.

Overall, the study findings suggest that an overriding factor affecting a person’s pain levels based on their personal income could be negative emotions related to their appraisal of their income ranking compared to their peers. Whether that be related to their perception of their own levels of deprivation relative to their peers (in keeping with Relative Deprivation Theory) or their standing in a society and a feeling of a lack of social mobility (Social Comparison theory).

In the study, analyses were made of data from the annual World Gallup Poll (GWP), across the years 2009-18, and consisting of responses from approximately 1.3 million adult survey respondents from across 146 countries.  Respondents were asked what their total monthly household income was before taxes, which was divided by the number of people in their household to derive the respondent’s personal income amount.  Respondents were also asked whether they experienced physical pain the day before being surveyed to which they could respond ‘yes’ or ‘no’. In the analyses, linear regression models were created from these data in addition to further ancillary information.

This study refers to pain as the feeling that people experience when their body hurts regardless of the presence of physical damage.

Physical pain is one of the main reasons people visit the accident and emergency room in the UK. Approximately nine million people live with chronic pain in the UK and musculoskeletal pain alone accounts for 30 per cent of the country’s medical consultations.

Physical pain has been increasing dramatically in the last decades, becoming a priority for global public health. Pain affects leisure and productivity at work, increases health care costs, and represents a major challenge for healthcare systems. Pain plays a key role in suicide and in drug and alcohol misuse. In light of these circumstances, understanding the context of pain is crucial to addressing its consequences.

Study author, Dr Lucía Macchia, said:

“This is the first study that shows that income rank and pain are linked around the world. It suggests that psychological factors related to the well-known phenomenon of social comparison may influence people’s physical pain.”

The study is published online in the journal, Social Psychological and Personality Science.

ENDS

Notes to Editors


To speak to Dr Lucía Macchia, contact Dr Shamim Quadir, Senior Communications Officer, School of Health & Psychological Sciences, City, University of London. Tel: +44(0) 207 040 8782 Email: shamim.quadir@city.ac.uk.

To read a copy of the embargoed manuscript for the study article (to be published 00.01 ET Monday 17 April, 2023):

‘Having less than others is physically painful: Income rank and pain around the world’ in the journal, Social Psychological and Personality Science

please request it from Dr Shamim Quadir, Senior Communications Officer, School of Health & Psychological Sciences.


City, University of London

  • City, University of London is a global higher education institution committed to academic excellence, with a focus on business and the professions and an enviable central London location.
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  • In the last REF, City doubled the proportion of its total academic staff producing world-leading or internationally excellent research.
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Natural flood prevention – higher trust through better communication

A UFZ study shows: If the population feels well informed, it has a more positive view towards nature-based flood prevention

Peer-Reviewed Publication

HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH - UFZ

Flood 

IMAGE: 2013 FLOOD ON THE RIVER ELBE NEAR DESSAU-ROSSLAU (GERMANY). view more 

CREDIT: ANDRÉ KÜNZELMANN/UFZ

There have been repeated flood disasters in Germany in recent decades. For example, in 2002 and 2013 along the Elbe and in 2021 in the Eifel region. As climate change progresses, severe floods are expected to occur more frequently. It is therefore important to quickly implement effective protection measures in vulnerable areas.

In the past, flood protection consisted mainly of technical solutions such as building dikes close to the river or constructing water retention basins. However, this is often no longer sufficient in order to be able to provide effective protection against flooding. Nature-based solutions such as dike relocation and floodplain renaturation are thus increasingly coming into focus in Germany and across Europe. “The aim of such projects is to give the river more space so that it can spread out during flooding and the renaturalised floodplains can fully develop their water-absorbing effect”, says Prof. Christian Kuhlicke, head of the UFZ Department of Urban and Environmental Sociology. “Natural flood prevention serves different purposes: It sustainably reduces the risk of flooding, restores the original state of the river landscape, increases biodiversity, and enhances the quality of life in the region”.

However, the local population is often sceptical or critical of natural flood protection measures. For example, there are fears that they might not be as effective as conventional technical flood protection. The interventions in the landscape appear drastic, and there is uncertainty as to whether the landscape will change for the better. The sudden proximity to the widening river can also seem threatening. “The relocated dike means that the water may get much closer to people’s home during high water levels. The fact that the river is now more visible can be frightening, especially for those who have often been affected by floods. However, these new measures can actually make things safer than before”, says Kuhlicke.

In their study, the UFZ team wanted to find out how people living near dike relocation areas perceive the natural flood protection measures and how well informed they feel. The research team interviewed 304 people from five towns and cities in Saxony-Anhalt on the Elbe (Lödderitz, Kühren, Aken, Rosslau, Vockerode), where measures for dike relocation or floodplain renaturation were carried out. The researchers developed a questionnaire based on a new social science research model (PRAM model), which facilitates the comparability of the surveys. The questionnaire comprised 18 questions to which the participants were asked to indicate their level of agreement on a scale of 1 to 7. For example: What is your attitude towards the dike relocation project? How powerless did you feel during this flood? I can completely rely on the public flood protection in my community. How likely do you think it is that a severe flood will occur in your community within the next five years?

“Our results show that both people who feel particularly connected to their home town and those who feel strongly threatened by flooding are more likely to oppose the measures. This was especially the case if these people had previously experienced a flood. In contrast, study participants who felt well informed and trusted local risk management were more likely to support nature-based measures”, explains Dr Sungju Han, a staff member at the UFZ Department of Urban and Environmental Sociology, former PhD student at the University of Potsdam, and lead author of the study.

But what do the results mean for the planning of future flood protection projects? “The fears and concerns of the population should definitely be taken seriously. Better information and communication – ideally at the onset of the planning phase – can allay many fears”, says Kuhlicke, who is the last author. “It is particularly important to make it clear that natural flood prevention is primarily about effectively protecting the population from the effects of major floods. And that is through allowing more space for the river. All other effects – the more natural river landscape or the increase in biodiversity – are positive side effects but not the primary goal. “If the population is not involved, there is often great resistance to flood protection projects. This is usually accompanied by considerable loss of time. And that can be dangerous – because you never know when the next flood will come”, says Han.

In addition to the study in Saxony-Anhalt, the UFZ team is conducting several other survey studies on this topic in different areas of Europe. They are part of the EU project RECONECT funded by Horizon 2020, the EU Framework Programme for Research and Innovation. As part of the RECONECT project, the UFZ aims to identify obstacles to the realisation of natural flood prevention. This is based on research in eight European countries. Han’s dissertation was supported by the German Academic Exchange Service (DAAD). 

Scientists discover pristine deep-sea coral reefs in the Galápagos Marine Reserve

Observations using the human-occupied vehicle Alvin are the first of deep-sea coral reefs in the Galápagos Marine Reserve

Peer-Reviewed Publication

WOODS HOLE OCEANOGRAPHIC INSTITUTION

newly discovered deep-water coral reef 

VIDEO: VIEW FROM HOV ALVIN DURING TRANSIT ACROSS A SECTION OF THE NEWLY DISCOVERED DEEP-WATER CORAL REEF view more 

CREDIT: VIDEO COURTESY OF L. ROBINSON (U. BRISTOL), D. FORNARI (WHOI), M. TAYLOR (U. ESSEX), D. WANLESS (BOISE STATE U.) NSF/NERC/HOV ALVIN, 2023 ©WOODS HOLE OCEANOGRAPHIC INSTITUTION

17 April 2023 - Galápagos, Ecuador – Scientists have discovered extensive, ancient deep-sea coral reefs within the Galápagos Marine Reserve (GMR) – the first of their kind ever to be documented inside the marine protected area (MPA) since it was established in 1998. The first reef observed was found at 400-600m (1,310-1,970 feet) depth at the summit of a previously unmapped seamount in the central part of the archipelago and supports a breathtaking mix of deep marine life.

Cresting the ridge of a submerged volcano, and stretching over several kilometers, the impressive reef structure was first recorded by Dr. Michelle Taylor (University of Essex, UK) and Dr. Stuart Banks (Charles Darwin Foundation, Ecuador) while diving in the deep-sea research submersible Alvin, operated by the Woods Hole Oceanographic Institution (WHOI, USA). This is the first time

HOV Alvin has explored this region within the GMR. The submersible recently completed upgrades that included improved high-quality still and ultra-high definition 4K video imaging systems, as well as enhanced sampling capabilities.

Taylor and Banks are part of an international group of scientists onboard the US Navy-owned and WHOI-operated research vessel R/V Atlantis, that is undertaking the Galápagos Deep 2023 expedition. The expedition is led by scientists at WHOI, University of Bristol (UK), Boise State University (USA), and University of Essex, in collaboration with the Galápagos National Park Directorate (GNPD), Charles Darwin Foundation and Ecuadorian Navy’s Oceanographic and Antarctic Institute (INOCAR). The expedition is funded by the US National Science Foundation (NSF) and Natural Environmental Research Council (NERC) in the UK.

Commenting on this groundbreaking discovery, the Minister of Environment of Ecuador, Jose Antonio Dávalos said: "This is encouraging news. It reaffirms our determination to establish new marine protected areas in Ecuador and to continue promoting the creation of a regional marine protected area in the Eastern Tropical Pacific. The richness of the yet explored depths of our ocean is another reason to strive towards achieving the commitments of the Global Ocean Alliance 30x30, which aims to protect at least 30% of the world's oceans by 2030, aligning sustainable economic activities with conservation."

Urchin on live coral (left) with Fossil coral, the foundation of the live reef, in the background

CREDIT

Image courtesy of L. Robinson (U. Bristol), D. Fornari (WHOI), M. Taylor (U. Essex), D. Wanless (Boise State U.) NSF/NERC/HOV Alvin/WHOI MISO Facility, 2023 ©Woods Hole Oceanographic Institution

Prior to this discovery, Wellington Reef off the coast of Darwin Island in the far north of the archipelago was thought to be among the few structural shallow coral reefs in the Galápagos Islands to have survived the 1982-83 El Niño event. The new discovery made during dives by scientists in the HOV Alvin shows that sheltered deep-water coral communities have likely persisted for centuries in the depths of the GMR, supporting rich, diverse, and potentially unique marine communities.

Dr Stuart Banks, Senior Marine Researcher at the Charles Darwin Foundation, and national observer on this expedition adds: “The captivating thing about these reefs is that they are very old and essentially pristine, unlike those found in many other parts of the world’s oceans. This gives us reference points to understand their importance for marine natural biodiversity heritage, connectivity with regional MPAs, as well as their role in providing goods and services such as carbon cycling and fisheries. It also helps us reconstruct past ocean environments to understand modern climate change. Open waters cover over 95% of the known GMR, of which less than 5% have been explored through modern research expeditions. It’s very likely there are more reef structures across different depths waiting to be explored. We’ll forge ahead with the Galapagos National Park Directorate and partners to help ensure that such newly discovered habitats are

folded into the GMR and Hermandad Marine Reserve planning process and recognized as part of their considerable world heritage value”.

Dr Michelle Taylor, co-lead of the expedition and Chair of the Deep Sea Society from the University of Essex notes the importance of this discovery for deep sea habitats: “The discovered reefs are novel for several reasons – in shallow reefs where finding 10-20% of coral cover would be considered a relatively unhealthy reef, in the deep-sea this is the norm. Dead coral skeletons making up the remaining 80-90% still provide homes for a huge diversity of life, which is less reliant on the live sections of coral. However, the reefs we’ve found in the last few days have 50-60% live coral in many areas, which is very rare indeed. They are pristine and teeming with life – pink octopus, batfish, squat lobsters and an array of deep-sea fish, sharks, and rays. These newly discovered reefs are potentially of global significance – a canary in the mine for other reefs globally – sites which we can monitor over time to see how pristine habitats evolve with our current climate crisis.”

Dr Daniel J. Fornari, co-lead of the expedition, marine geologist, and Emeritus Research Scholar at the Woods Hole Oceanographic Institution who has mapped and sampled the marine environment in the Galápagos for over 20 years notes: “Exploring, mapping and sampling the Galápagos Platform with Alvin and Atlantis represents an opportunity to apply 21st-century deep-submergence and seafloor mapping technologies and innovative deep-sea imaging techniques to reveal the beauty and complexity of the volcanic and biological processes that makes the Galápagos so unique".

Scientific findings such as this help inform effective management and conservation actions. The discovery also comes at a time when the Eastern Tropical Pacific countries of Panama, Costa Rica, Colombia, and Ecuador are actively collaborating through a regional Marine Corridor (CMAR) initiative to protect and responsibly manage the ocean upon which we as people depend. Newly declared MPAs such as the Hermandad Marine Reserve (HMR) now connect seamounts in Ecuadorian waters to offshore marine environments such as Costa Rica’s Cocos Island National Park. Natural oceanographic and marine processes transcend national boundaries, which underscores the need for special measures that protect foraging grounds, migratory routes for marine life and sustain responsible fisheries.

For more information about the expedition objectives, scientists and the R/V Atlantis and HOV Alvin, please visit: https://galapagosdeep2023.com/