Wednesday, December 18, 2024

 

Is fake meat good to eat? Processed plant-based meat alternatives linked to depression risk in vegetarians


DOES THAT HAPPEN TO SEVENTH DAY ADVENTISTS TOO?!


University of Surrey



There is mounting evidence suggesting that ultra processed foods (UPF) are bad for our health; but if you stick to a vegetarian diet, is that still the case?  Plant-Based Meat Alternatives (PBMA) are considered to be ultra-processed foods and may be associated with similar harms. 

In the first study of its kind, published in Food Frontiers, researchers from the University of Surrey found that vegetarians who consumed PBMAs had a 42% increased risk of depression compared to vegetarians who refrained from PBMAs. 

The study, which was led by Hana Navratilova, analysed data from the UK Biobank and found no notable differences in intake of sodium, free sugar, total sugar, or saturated fatty acids between those vegetarians who ate PBMAs and those who did not. The researchers did find, however, that those who eat PBMAs had higher blood pressure and C-reactive protein (CRP) levels, a marker of inflammation, and lower levels of apolipoprotein A, a protein associated with HDL, a “good” cholesterol; PBMA consumption was, however, also linked to a reduced risk of irritable bowel syndrome (IBS) by 40%. 

Professor Nophar Geifman, from the School of Health Sciences at the University of Surrey, and senior author of the study, said:  

"The overall findings are reassuring, suggesting that plant-based meat alternatives may be a safe option when they are part of an overall balanced diet. However, the potential link between these types of food, inflammation and depression warrants further investigation." 

The study presented some limitations due to the data collected, which was predominantly from a white population in the UK, and dietary information only being gathered at the beginning of the study, not accounting for potential changes over time. 

Professor Anthony Whetton, co-author of the study from the School of Veterinary Medicine at the University of Surrey, said: 

“Ultra-processed plant-based meat alternatives can be a useful way for people to transition to a vegetarian diet effectively, and that helps with sustainable agricultural practices.  Further research, including longitudinal studies and trials with more diverse populations, is necessary to confirm these findings and the relationship between vegetarian foods and mood." 

 

 

[ENDS] 

 

  • Prof Nophar Geifman is available for interview, please contact mediarelations@surrey.ac.uk to arrange.   

  • An image of Prof Nophar Geifman is attached. 

SHAMANIC STRING THEORY

String figures shed light on cultural connections and the roots of mathematical reasoning




University of Helsinki
String figure 

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String figure.

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Credit: Roope Kaaronen's research group




New research suggests that the making of string figures, a globally documented practice, may point to shared cultural heritage stretching back millennia. The research offers a new way to investigate the evolution and distribution of cultural phenomena using mathematical methods.

A collaborative study between the University of Helsinki, Aarhus University, the National Museum of Denmark and Seattle University examined the cognitive, cultural and historical significance of traditional string figures. String figure games involve the manipulation of a loop of string with the fingers to create complex patterns. The study explored whether certain string figures evolved independently in different parts of the world or share a common ancestry.

The researchers analysed 826 string figures from 92 cultures around the world. They found 83 recurring designs. The results show that certain figures are globally prevalent. In certain cases, this suggests ancient cultural origins potentially extending back millennia.  

“Strikingly similar string figuress appear in, for example, the North American Arctic cultures or in the Pacific region. These are examples of how people have transmitted traditional string figures through migration and contact over centuries or even millennia. We also noted that some figures appear only in restricted regions, which may indicate both isolation and local innovation,” explains Postdoctoral Researcher Roope Kaaronen of the Faculty of Biological and Environmental Sciences.

Combinations of arts, crafts, play, storytelling and mathematical reasoning

String figures are a tangible example of cultural artifacts that combine art, crafts, play, storytelling and mathematical reasoning. Such traditions shared across humanity may help in understanding human creativity, cognitive evolution and the origins of mathematical thinking.

“String figures demonstrate the human drive to seek and develop cognitively challenging forms of entertainment, such as more recent games like chess or sudoku,” says Kaaronen.

A ‘family tree’ of string figures

The researchers applied mathematical knot theory to develop a computational method to create a DNA-like symbolic representation of each string figure. This enables the cross-cultural comparison of string figures and the construction of their “family tree”.

The method also enables the study of the evolution of numerous other early human technologies, which may help archaeologists and anthropologists investigate cultural heritage in a novel way.

“The analysis methods we developed can be extended to the quantitative study and cross-cultural comparison of other objects made of string, cord, thread or rope, such as knots, fishing nets and textiles. Digital methods and computational tools allow us to preserve and understand this cultural heritage better and to ensure its transmission to future generations,” summarises Kaaronen.

Resource-rich countries still often invest unsustainably




Radboud University Nijmegen




Countries that earn a lot of money from oil, coal, minerals and other natural capital by no means invest it wisely. A lot of money flows away into corruption and unsustainable investments. Investing more sustainably in education, health and infrastructure would benefit not only current, but also future generations within these countries. Charan van Krevel investigated why things still often go wrong. His PhD defense at Radboud University takes place on 21 December.

Van Krevel's research shows that in countries with abundant natural capital that make poor investments, there is not ‘just’ apathy or aversion towards sustainable development, but that there are systematic, economic and institutional factors causing this policy failure. It sounds very logical: using your country's resource profits to help the entire population move forward not just in the short term, but in the long term. Yet it often fails to happen this way.

Well-known are the stories of corruption and missing money in poor countries in Asia, South America and Africa, as well as scenarios where rich Western companies make off with the profits. But there is more to it, the economist outlines. Van Krevel used data from more than 140 countries for his research, to understand how they spend their natural capital, and which investments were most effective in the long run. ‘What you often see is countries that are already developing sustainably continue to do so even as new natural capital is mined,’ Van Krevel explains.

Corruption

In his research, Van Krevel looks at the causes of the lack of investment in the future. He finds evidence that (international) companies are skimming off profits so that there is little left to invest with. So corruption is not only at government level, but also in deals with business. There is simply not enough left over to invest.

The economist made an extensive study of Indonesia: ‘It has numerous natural resources, including palm oil, gas, coal and more. That's given the country a lot: incomes have risen, but there have not been enough investments that contribute to the long-term welfare of its people. But it also has some interesting governance quirks: in Indonesia, the local government is responsible for the sustainable investments and often does it better than national governments would. In the Netherlands, if not The Hague but Groningen had spent the money from gas, investment choices would probably have been more sustainable.'"

'Furthermore, data doesn't paint the full picture. Look at Cambodia, for example. That country signed contracts with China to mine limestone. On paper, you see big investments by China in infrastructure in the country. But in practice, this then turns out to be, for example, a highway from the capital to a coastal town, where many politicians and other rich residents have second homes.'

Norway and Botswana: a better way?

Van Krevel: 'There are examples of things working out better, of course. Norway set up a fund with profits from natural capital that politicians have little or no access to. Its interest is invested in free education, good libraries and more things that benefit the population. Botswana also made good investments with money from mining, and has become relatively quite prosperous. The political climate and aversion to the colonial past made for smart choices.'

Although Van Krevel's research focuses mainly on fossil fuel profits, he says there are plenty of lessons for countries like Congo that are sitting on a lot of other natural capital: minerals like lithium and cobalt, important for many of the tech we use every day. 'Those countries have an opportunity to learn. Make sure your property rights are well organised, and not just vested in the elite or Western parties. With democratic control, you significantly increase the chances of sustainable development.' 

 

Salmon genes unlock secrets of puberty and evolution




University of Helsinki
Atlantic salmon 

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Atlantic salmon

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Credit: Pekka Tuuri




A study carried out at the University of Helsinki shows how a single gene in Atlantic salmon can dramatically influence the timing of puberty - a key factor for salmon life cycle and survival.

Researchers discovered that the gene, known as vgll3, acts as a master regulator, controlling thousands of other genes involved in various aspects of salmon sexual maturation.

"Imagine a single switch determining whether puberty begins at age 13 or 20 in humans. Vgll3 plays a similar role in salmon, influencing traits like when reproductive cells start to develop, growth patterns, and behavioral changes. Our results explain how genetic variation in a single gene can have such dramatic effects on very complex and multifaceted traits as puberty or maturation age," explains Associate Professor Jukka-Pekka Verta, now at Nord University, Norway, who conducted this study as a part of his post-doctoral research at the University of Helsinki. 

This discovery not only explains how complex traits like puberty onset evolve and vary but also highlights a process called "pleiotropy," where one gene affects multiple characteristics, like the conductor of an orchestra. 

The Vgll3 gene is involved in controlling pubertal timing in humans, but it has a much smaller influence. The same gene has a much larger effect, and is kind of a switch, on an auto-immune skin disease in humans. This disease, lupus, is much more common in females than males. 

Hydroelectric dams can affect salmon maturation

The findings have far-reaching implications, particularly for understanding rapid evolutionary changes in salmon populations affected by human activities, such as hydroelectric dam development. 

As salmon are a migratory species, they need a clear pathway between their breeding grounds in the river and their feeding areas in the ocean. Many hydroelectric dams do not have functioning fish ladders, and this can block all the breeding areas above a dam. 

“If the areas for breeding below the dam are only suitable for example, for smaller salmon, there might be very strong natural selection against the ‘late maturation vgll3 variant’, which is a means for the salmon population to adapt to the changed conditions, but this also reduces the diversity of the population which can have longer term negative consequences. Now we better understand what other genes and processes may be affected by such changes.” describes Professor Craig Primmer from the Faculty of Biological and Environmental Sciences, University of Helsinki

By altering the frequency of certain vgll3 variants, natural selection can drive significant changes in traits like size, number of eggs and behavior. This research underscores the importance of fundamental evolutionary studies in managing wild populations and predicting how environmental changes impact ecosystems.

 

Most retail choice offers for electricity don’t save consumers money



72% of offers more costly than the utility’s default price


Ohio State University


COLUMBUS, Ohio – Ohio’s retail choice electricity market – which lets consumers choose which company provides their electric generation service – has provided residential consumers with mostly cost-increasing offers.

Researchers found that 72% of the most popular type of retail electricity offers over the past decade have been significantly above the default price consumers would pay if they didn’t shop around.

The results suggest that there are persistent market failures in the deregulated market, said Noah Dormady, lead author of the study and associate professor at The Ohio State University’s John Glenn College of Public Affairs.

“The bulk of the offers provided to Ohio consumers are way above what those consumers would pay if they did nothing,” Dormady said.

“Historically, consumers would be better off if they just stayed with their electrical utility’s default price, rather than switching service to the median retail choice offer.”

Dormady noted that these markets have offered many Ohio households and businesses with cost-saving supply offers over the years, and those suppliers that have offered competitive pricing based on market fundamentals have delivered value to Ohio. “It’s unfortunate that cost-saving offers have been so few and far between,” he added.

The study was published recently in the Journal of Critical Infrastructure Policy.

The study was done in Ohio, but it has relevance throughout the United States and even internationally where similar retail choice marketplaces have existed for years.

“The problems we document here exist in other states and in parts of Canada and Australia, too,” he said. “We are continuing the work we did here in other states to learn more.”

Dormady and his colleagues built the largest and most detailed database of retail electricity choice offers ever in a published study.  They examined every electricity offer made to Ohio consumers by retail marketers over a nine-year period from 2014 to 2023 – more than 2 million records.

Households that cannot or choose not to shop for retail electricity generation service stay with their utility’s default service. This excludes areas where default service is provided through municipal aggregation. Customers who choose to shop can purchase service from among competing supply offers from one of about fifty different suppliers in each of the six major utility service territories in the state. All customers, whether they purchase their generation from a competing supplier or stay on the utility’s default service, continue to receive their distribution service from their local utility.

Consumers are overwhelmed with choices, Dormady said. Every day, between 90 and 150 different supply offers are filed by about 45 different suppliers with the Public Utilities Commission of Ohio (PUCO), which is the state agency overseeing the market.

Offers vary widely, some offering a fixed rate for a defined period and others offering variable rates. And some offer “gimmicky” deals, he said, with deceptively low initial costs combined with high monthly fees and consumption caps of how much electricity can be used before rates jump or financial penalties.

The study found that with the most commonly sought-after rate by residential customers – a 12-month fixed rate – competing electric companies offered rates above the default utility standard offer 72.1% of the time.

What’s more, the study found that competing companies historically made offers that averaged 25% to 30% above the standard offer. But when they offered cost savings, they were only 5% to 10% below the standard offer.

“The savings are considerably smaller than the price increases they offer,” Dormady said.

Dormady noted that all the competing companies buy their electricity from the same wholesale markets.  Under standard economic theory, the retail prices would be set based on the wholesale prices. Instead, it appears that companies are competing based on the standard price, which is already marked up about 73% over the price on the wholesale market.

The median retail choice offer by competing companies is 98% above the wholesale cost of electricity, the study found.

Another issue is that the best prices are not always available to consumers. The researchers found that cost-savings offers were available between 43% and 59% of the days of the year, depending on the year studied.

“Even if consumers shopped for the best prices on electricity every day – which most people are not going to do – they would only find savings about half the time,” he said.

Dormady said future studies will examine more thoroughly the issues consumers face in shopping for retail electricity.  But it appears that the markets as they are currently set up are too complex for most households and make it too difficult to identify the deals that are best for them.

Despite the problems with the current market, Dormady said he and his colleagues don’t believe the answer is to move back to a regulated system. That will not create the best situation for consumers.

Instead, there is a need for more efficient markets and greater transparency. One suggestion the researchers have is creating an Office of the Independent Market Monitor to ensure that the markets operate efficiently.  While existing offices such as PUCO and the Consumers’ Counsel play key roles, they have multiple functions and can’t be considered a replacement for a dedicated independent market monitor. Independence and market expertise are key, Dormady said.

Another suggestion is to establish a “supplier scorecard” that rates the quality and competitiveness of competing electric suppliers. This scorecard would function similarly to a Better Business Bureau, Fitch or Moody’s rating, he said.

“We need to make it easier for consumers to identify the electricity offers that will save them money and that are right for them,” Dormady said. “Unfortunately, it is too easy to confuse consumers in a complex market like this.”

The study was supported by the Alfred P. Sloan Foundation.

Other Ohio State co-authors were Yufan Ji, Stephanie Pedron and Abdollah Shafieezadeh. Additional co-authors were William Welch of Welch and Associates Consulting; Alberto Lamadrid and Samatha Fox of Lehigh University; and Matthew Hoyt of Exeter Associates.

 

Gruyère cheese, or a history of the domestication of bacteria



University of Lausanne
Culture of mini cheese 

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A scientist seeding milk with ‘cheese starter cultures’ to initiate fermentation into mini cheeses.

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Credit: Jérôme Beneditti, UNIL




The domestication of plants and animals has played a key role in the development of human societies. And microbes, too, have been tamed: a study by UNIL, published in the journal Nature Communications, shows that the bacteria used to produce Gruyère, Emmental and Sbrinz cheese show signs of ancient domestication.

The domestication of livestock and plants marked an important stage in the settlement of human populations in the Neolithic period, as they moved from a hunter-gatherer lifestyle to a subsistence model based on animal husbandry and agriculture. Because of the microscopic size and virtual absence of fossils of micro-organisms, their domestication is more difficult to prove than that of flora and fauna. Although several studies have already demonstrated this in the case of yeasts (microscopic, single-celled fungi with nuclei), the case of bacteria (micro-organisms that are mainly single-celled and have no nuclei) has yet to be elucidated. This was the objective of Vincent Somerville, a former doctoral student in Philipp Engel's team at the Department of Fundamental Microbiology (DFM) in the Faculty of Biology and Medicine at UNIL. The results of his latest study, carried out under the co-direction of Florent Mazel and in collaboration with Agroscope, have been published in the journal Nature Communications.

An old process

Domestication consists of artificially selecting - generation after generation - variants of a wild species that have developed interesting characteristics for agriculture or livestock farming, such as the nutritional quality of plants or the size and docility of animals. As human population has grown throughout history, and food demand has increased, long-term storage solutions were needed. ‘This is the case with fermentation, which converts sugars into acids, protects against the proliferation of undesirable microbes and therefore enables food to be preserved for longer,’ explains Philipp Engel, co-director of the study. This technique, which dates back several thousand years, uses micro-organisms such as yeast to make beer or wine, or bacteria to make cheese. The first indirect archaeological evidence of milk fermentation dates back around 10,000 years, to the Neolithic period.

Swiss cheeses as study subjects

Thanks to collaboration with Agroscope, the Swiss centre of competence for agronomic and food research, the Lausanne group had access to a collection of bacterial strains used in the production of three different Swiss cheeses: Gruyère, Emmental and Sbrinz, and stored for 50 years. ‘These cultures, also called “cheese starter cultures” were partially reactivated to create some sort of laboratory mini cheeses’, explains Vincent Somerville, first author of the article. ‘We then analysed the evolution of the genetic and phenotypic characteristics of this collection over time in order to identify markers indicative of domestication. By observing more than 100 bacterial isolates and almost 1,000 samples, the scientists found, respectively, low genetic diversity and high stability of traits specific to the food preservation process (for example, acidification) over this half-century period. Those are indicators of an ancient, or even very ancient, adaptation, which by extrapolation corresponds to the appearance of the first fermented dairy products. ‘The temporal concordance between the dating of the micro-organisms and the archaeological history of this fermented food was quite unexpected’, enthuses researcher Florent Mazel. In other words, it is possible to trace the past of the domestication of bacteria from Swiss cheeses.

Guaranteeing food safety

In the future, cheeses from different parts of the world could be compared in order to generalize the study. In addition, research into the domestication of bacterial communities used to initiate the fermentation of other products, such as kefir, looks promising. ‘A better understanding of bacterial domestication will enable us to optimize the characteristics of these microbiota, improve the use of this process and make it a more sustainable method of food storage’, hopes Florent Mazel.

 

Additional link:

More info on the Swiss National Centre of Competence in Research (NCCR) Microbiomes

 

Do teachers view parents as partners in the education of their child? Not so much…


New research from Ben-Gurion University highlights teachers' tendencies to label parents as the problem


IT IS HOW TEACHING IS TAUGHT NOT AS A SOURCE FOR GERNERAL KNOWLEDGE TRANSMISSION BUT  AS A SPECIALIST; SEPERATE FROM THE MASSES



Ben-Gurion University of the Negev



BEER-SHEVA, Israel, December 17, 2024 – Many parents are more involved than ever in their children's education at school. They are in contact with the teachers on a regular basis, discuss their teaching style and generally advocate for their child. Ostensibly, the ideal relationship would be a partnership between teacher and parent with the child in the center. However, a new study from Ben-Gurion University of the Negev shows that teachers often view parents as a problem, often more problematic than their children, to be managed rather than as partners.

Tamar Schejter-Cohen, Prof. Idit Fast and Prof. Dorit Tubin of the School of Education interviewed 16 elementary school teachers in two schools in Beer-Sheva to assess how they view parents. What arose from the interviews was a recurring theme of managing the obstruction that is parents' input rather than a partnership for the benefit of the child.

Currently, teachers often need to figure out how to handle parents on their own through trial and error. Therefore, the researchers recommended increased professional training for teachers to diagnose, treat and infer various modes of parenting to add to their professional toolbox.

Their findings were published last month in Teachers and Teaching.

The researchers found that teachers identify three parenting styles: cooperative, uninvolved, and interfering.

Cooperative parents are appreciative of the teacher's efforts and volunteer information. Teachers then reciprocate willingly with updates.

Uninvolved parents were the largest category. They show up for the mandatory school meetings but are otherwise unresponsive to teachers' calls and messages. Teachers will often send messages to remind them they need their cooperation at home to do their job at school.

Finally, the research showed that teachers have developed entire systems to deal with interfering parents. Interfering parents come in many varieties: deniers, over-protective, worried, anxious, aggressive, unpredictable, demanding, nagging, childish, blamers, complainers, boundless and hostile.

The researchers found that teachers had developed their own systems to "handle" these parents, often moving back and forth between strictness and empathy. They "diagnosed" the parental type and then "treated" them accordingly. Afterwards they "inferred" whether their diagnosis and treatment needed to be revised.

Schejter-Cohen, Prof. Fast and Prof. Tubin noted that process was a professional skill the teachers had to invent on their own. Therefore, they recommended adding courses that would teach teachers how to diagnose, treat and infer parental styles.

They contended that doing so would have a few benefits. It would increase the teachers' professionalism. It would also increase school legitimacy in the community. Since parents are increasingly involved in school, if they had good relationships with teachers they would think better of the school.

"By giving the teachers the proper professional tools, they can really turn parents into partners," the researchers concluded.

The study was supported by the Lion Family Foundation.

UC3M investigates how to improve seat belts with a gender perspective

Universidad Carlos III de Madrid
News Release 17-Dec-2024


Road safety for women
Credit: UC3M

Researchers at Universidad Carlos III de Madrid (UC3M) are carrying out a pioneering study that aims to analyse how morphological differences between men and women can influence the effectiveness of road safety systems, specifically seat belts, in order to develop more inclusive safety systems.

“We realized that until now no previous studies had been done on how gender differences can influence road safety and the wearing of seat belts. That's why we included it in our experiments,” explains Silvia Santos Cuadros, from the UC3M Department of Mechanical Engineering. “In fact, many of the studies in this field have used male models as a reference, ignoring the anthropometric diversity of women.”

With this research, financed by the Community of Madrid through the agreement-subvention for the encouragement and promotion of research and technology transfer at Universidad Carlos III de Madrid (ORIGEN-CM-UC3M), the aim is to increase the protection of vehicle occupants regardless of gender in the search for a safer and more inclusive future. This is key, since anatomical and behavioural differences could mean women face a greater risk of muscular or cervical injuries due to limitations in the design of current belts during emergency braking, according to the researchers.

“This project can provide valuable information to improve not only the future safety of autonomous vehicles, but also that of current means of transport such as trains, buses or subways, where sudden decelerations can cause injuries,” says Silvia Santos.

To carry out the study, they have designed a series of tests in which women with different anthropometric characteristics will travel in instrumented vehicles, with sensors that will measure their biomechanical response at the articular, kinematic and muscular level during different situations, such as braking in autonomous vehicles in the direction of travel or in reverse. The data obtained will be analysed with artificial intelligence tools in order to identify patterns that can help improve current safety systems and to analyse how the seatbelt affects passenger safety.

“For this reason, the university is inviting women of different ages and physical characteristics to participate in this study,” says Eva Herrero, from the UC3M Department of Communications, who is seeking collaboration in order to ensure that safety systems are inclusive and effective. “With this research, the university is reaffirming its commitment to the transfer of knowledge to society. In fact, it is thanks to the collaboration of different sectors that this type of synergistic project can be carried out, showing how scientific research can have a direct impact on people's daily lives,” she adds.

Another of the objectives of this project, which also involves the UC3M Department of Communication, is to analyse the presence of gender in institutional campaigns on road safety in order to carry out more inclusive prevention actions. “This will help to highlight all the different circumstances and provide a more comprehensive and inclusive knowledge of road safety,” concludes Herrero, who is also a member of UC3M's University Institute of Gender Studies (IEG).

More information: https://www.uc3m.es/investigacion/origen

Video: https://youtu.be/Crs2RrJnu5k


 

Simulating natural selection in assisted reproduction



PNAS Nexus
ART graphic 

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Assisted reproductive technologies (ART) can bypass female-modulated sperm selection (top of figure) that ensure that genetically compatible or competent sperm are used for fertilization. ART can also introduce a range of novel environmental stressors (bottom of figure) that generate epigenetic modifications in offspring. Failure to design procedures that both mimic natural conditions and mitigate the harmful effect of unnatural environmental conditions during ART can impact the health trajectories of ART offspring and potentially their descendants. 

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Credit: Jonathan P. Evans and Francisco Garcia-Gonzalez




A Perspective summarizes the risks of bypassing natural selection when using assisted reproductive technologies (ART) in humans and livestock. The authors call for dialogue between the fields of assisted reproduction and evolutionary biology.

Jonathan P. Evans and Francisco Garcia-Gonzalez detail how techniques used in ART, including in vitro fertilization, artificial insemination, and intracytoplasmic sperm injection, can stress and damage gametes and embryos and lead to deleterious epigenetic changes in offspring. Some ART techniques also bypass a system of filters in the female reproductive tract that select healthy sperm and may lead to better genetic matches with the egg. ART-conceived offspring have higher risk of certain health problems than spontaneously conceived offspring, including preterm birth, congenital abnormalities, low birth weight and associated mitochondrial genotypes, childhood cancers, asthma, obesity, metabolic syndrome, diabetes, cardiovascular diseases, and neurodevelopmental and psychiatric disorders. Some of these health risks could potentially be ameliorated by sorting sperm with techniques that mimic the filters in the female reproductive tract and incorporating female reproductive fluids—which play a critical selective role in filtering high quality sperm in vivo—into ART protocols. According to the authors, applying evolutionary principles to the future development of ART may improve outcomes both for human ART and animal production.