Tuesday, October 03, 2023

For Iranian refugees, French wine harvest part of anti-government 'struggle'

Agence France-Presse
October 3, 2023 

Marjan Jangjoo was a yoga and snowboarding instructor before fleeing Iran
 (Christophe ARCHAMBAULT/AFP)

Swapping their state-enforced veils for T-shirts reading "life" and "liberty", a group of Iranian women who have fled to France now help make wine that traces its roots back to ancient Persia.

"We won't stop, we will keep fighting. The struggle against the mullahs, the Islamic republic, is going on here in a different way," said Marjan Jangjoo, her head bared to the rain in a vineyard in France's western Dordogne region.

"The revolution won't be done in a day, but it's on the move," she added.

Jangjoo, 32, was once a sports coach teaching aerial yoga and snowboarding near Iran's southwestern city of Shiraz.

But she fled last November when security forces came to arrest her, spending months on a gruelling slog through snowy mountains without appropriate clothing.

Jangjoo took part in the protests that erupted in the wake of the custody death of Mahsa Amini who had been arrested for allegedly flouting the dress code.

She was a member of a local Shiraz mountain club whose members were targeted by the Iranian authorities during the protest movement, with several arrested.

An experienced trekker and marathon-runner, Jangjoo eventually made it on foot to the Kurdish-controlled region of northern Iraq.

Support from people in France helped get her case noticed by the French consulate in Erbil, speeding her on the way to Europe.

In the Dordogne, "we're fighting hand-to-hand to keep our wine alive", said Jangjoo, who is now now seeking asylum in France.

Her friend Soodeh Lashkarizadeh, 33, said "the regime wants to destroy happiness, like you get from dancing, sports or drinking wine".

She fled to the Netherlands in 2018 after attracting negative attention for removing her hijab while playing cricket.

- Ancient grapes -

"There is tough repression against sportspeople in Iran, because working-class young people identify with them and sport transmits values," said Chowra Makaremi, an Iranian-born anthropologist at France's National Centre for Scientific Research (CNRS).

She backed Jangjoo's long quest to make it to France.

And it is in the vineyard of Makaremi's brother Masrour that the young women are now bringing in the harvest.


On Masrour's land in the village of Saint-Meard-de-Gurcon, vines are heavy with Syrah grapes.

The variety is closely identified with the Rhone valley in eastern France, but one legend has it that it was originally brought back from Persia by people returning from the crusades.


Makaremi ferments the wine -- a vintage set to be dubbed Cyrus after the founder of the Persian Empire -- in terracotta amphoras, rather than more typical French casks.

Inspired by 5,000-year-old methods, a natural resin derived from pistachio trees is used to seal the porous material.


Bringing history closer still is a single amphora dating to the last dynasty to hold the Persian throne before the seventh-century Arab conquest.

A small part of the wine will be fermented in the relic vessel, bought by Masrour Makaremi at auction.


- 'Same fight' -


"Iranians' aspiration to freedom isn't only about revolting against the existing regime, it is fed by deep roots in Persian civilisation," said orthodontist and neuroscientist Makaremi.

For him, producing his roughly 6,000 bottles a year is "an act of resistance joined to the rebirth of Persian culture" -- not least through "the very hands that harvest the grapes".

Makaremi sees the young women among the vines as part of the "same fight" that claimed the life of his mother, Fatemeh Zarei who was executed in 1988.

After his mother's death, Makaremi and his sister rejoined their father in exile in French city Limoges.

But he still remembers "walking with my grandmother among the vines" near his hometown of Shiraz.


The city's millenia-old wine tradition lived on in his uncle, who "made his house wine on the quiet".

Demonstrations against the regime inspired by Mahsa Amini's death appear to have died down for now inside Iran after months of harsh repression.

But Makaremi hopes against hope that he will one day plant new vines in the soil of home.

"Or else it will be my children who go after that adventure," he says.

Here with a Loaf of Bread beneath the Bough,
A Flask of Wine, a Book of Verse—and Thou
 Beside me singing in the Wilderness—
And Wilderness is Paradise enow.

Three scientists win Nobel Prize in physics for looking at electrons in atoms during split seconds
Agence France-Presse
October 3, 2023 

The Nobel Prize in physics has been awarded to Anne L'Huillier and Pierre Agostini of France and Austrian-Hungarian researcher Ferenc Krausz.© DR

Pierre Agostini of The Ohio State University in the US; Ferenc Krausz of the Max Planck Institute of Quantum Optics and Ludwig Maximilian University of Munich in Germany; and Anne L’Huillier of Lund University in Sweden won the award.

The laureates are being recognised “for their experiments, which have given humanity new tools for exploring the world of electrons inside atoms and molecules. They have demonstrated a way to create extremely short pulses of light that can be used to measure the rapid processes in which electrons move or change energy", the jury said in a statement.

Hans Ellegren, the secretary-general of the Royal Swedish Academy of Sciences, announced the prize Tuesday in Stockholm.

The Nobel Prizes carry a cash award of 11 million Swedish kronor ($1 million). The money comes from a bequest left by the prize’s creator, Swedish inventor Alfred Nobel, who died in 1896.

Nobel Prize in medicine awarded to Katalin Kariko, Drew Weissman for Covid 19 vaccine research

Agence France-Presse
October 2, 2023 

Thomas Perlmann, secretary of the Nobel Assembly, right, announces the winner of the 2023 Nobel Prize in Physiology or Medicine to Katalin Kariko and Drew Weissman, at the Karolinska Institute in Stockholm, on October 2, 2023.© Jessica Gow, AP

The pair, who had been tipped as favorites, were honored “for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19,” the jury said.

“The laureates contributed to the unprecedented rate of vaccine development during one of the greatest threats to human health in modern times,” it added.

The pair will receive their prize, consisting of a diploma, a gold medal and a $1 million cheque, from King Carl XVI Gustaf at a formal ceremony in Stockholm on December 10, the anniversary of the 1896 death of scientist Alfred Nobel who created the prizes in his last will and testament.

Last year, the Medicine Prize went to Swedish paleogeneticist Svante Paabo, who sequenced the genome of the Neanderthal and discovered the previously unknown hominin Denisova.

The Nobel season continues this week with the announcement of the winners of the Physics Prize on Tuesday and the Chemistry Prize on Wednesday.

They will be followed by the much-anticipated prizes for Literature on Thursday and Peace on Friday.

The Economics Prize winds things up on Monday, October 9.

(AFP)


Nobel-winning mRNA pioneer Weissman now wants to defeat Covid forever

Agence France-Presse
October 3, 2023 

Drew Weissman (Mandel NGAN/AFP)

From developing a one-and-done coronavirus shot to overcoming misinformation and global vaccine inequity, Nobel prize winner Drew Weissman says that at 64, he's only "speeding up."

The University of Pennsylvania immunologist was awarded the biggest accolade in medicine on Monday for his pioneering research on messenger RNA, the technology behind Covid-19 vaccines that changed the course of the pandemic.

"What happened is I got a cryptic text from Kati around four in the morning," he said in an interview with AFP, referring to his old friend, collaborator and Nobel co-winner Katalin Kariko.

She had received word from the Nobel committee that they had finally won after being passed over the past couple of years -- but they weren't sure it was real until the official announcement.


"We were wondering if somebody was pulling a prank on us!" he said.

The honors have been piling up for Weissman: the Lasker Award, the Breakthrough Prize, and many more -- though he says the Nobel was always the "ultimate," something he had dreamed of since the age of five, when he first became interested in how things work.

Having just turned 64, and helped the world tame a virus that killed an estimated seven million worldwide, he could be forgiven for considering a well-earned retirement.


But Weissman says there's too much work left to be done. "I'm speeding up and my wife and family aren't happy about it," he joked. "I'm in a good spot."

- 'Ultimate' vaccine -

First on his quest: how to improve upon Covid-19 mRNA vaccines, which have saved countless lives by protecting incredibly well against severe disease and death.

Weissman says the next step in their evolution is universal shots that will be far better than the annualized boosters currently on offer.

A "pan-coronavirus" vaccine he is working on with an international team "should cover all future variants -- and any bat coronaviruses that might cross over into people," he said.

Though coronaviruses are known to mutate fast, Weissman teamed with AI specialists to comb through their structures, which contain roughly 30,000 "nucleotides" or building blocks, in search of "conserved regions" that stay the same.

They have shown it works in animals, and now hope to begin human trials within the next six months. "We think that's going to be the ultimate vaccine," he said.

In all, his lab is developing 20 different mRNA vaccines, with seven already in human trials, protecting against everything from rare autoimmune disorders to food allergies and heart disease.

"We've really expanded our scope of research -- and that's been allowed because the world... now recognizes RNA as important," he said.


It's a far cry from Weissman's anonymity during the 1990s and 2000s when he and Kariko made their key discoveries about how mRNA could be harnessed.

Unlike traditional vaccines, messenger RNA vaccines deliver genetic instructions to turn some of the host's cells into virus-like particles, training the immune system for when it encounters the real deal.

- Misinformation and equity -


Of course, scientific advances need to reach people to make a difference, and to this end Weissman is part of a group working to tackle hesitancy at the global level.

"There's one group who refuse to take the vaccine no matter what -- they follow politicians who submit laws to try to make RNA vaccines illegal in the United States," said Weissman, referring to a Republican-backed bill in Idaho.

But those on the fence -- including conservatives, African Americans, the elderly and others -- may respond to targeted messaging that'll resonate, he added.


He's also involved in setting up production sites in low and middle-income nations, with the first, in Thailand, developing dengue and tularemia vaccines.

It's "an incredibly important thing to give access to RNA technology to every part of the world," he said. "Pfizer and Moderna aren't going to have a big interest in making a vaccine for tularemia," a rare but serious zoonotic disease that is virtually absent in developed countries.

"But if they've got production sites and researchers locally, who want to do it, then they've got everything they need."

BETTER LIVING THROUGH CHEMISTRY
Psychedelics plus psychotherapy can trigger rapid changes in the brain − new research at the level of neurons is untangling how

The Conversation
October 2, 2023 


Psychedelic art (Shutterstock)

The human brain can change – but usually only slowly and with great effort, such as when learning a new sport or foreign language, or recovering from a stroke. Learning new skills correlates with changes in the brain, as evidenced by neuroscience research with animals and functional brain scans in people. Presumably, if you master Calculus 1, something is now different in your brain. Furthermore, motor neurons in the brain expand and contract depending on how often they are exercised – a neuronal reflection of “use it or lose it.”

People may wish their brains could change faster – not just when learning new skills, but also when overcoming problems like anxiety, depression and addictions.

Clinicians and scientists know there are times the brain can make rapid, enduring changes. Most often, these occur in the context of traumatic experiences, leaving an indelible imprint on the brain.

But positive experiences, which alter one’s life for the better, can occur equally as fast. Think of a spiritual awakening, a near-death experience or a feeling of awe in nature.


A transformative experience can be like a fork in the road, changing the path you are on.
Westend61 via Getty Images

Social scientists call events like these psychologically transformative experiences or pivotal mental states. For the rest of us, they’re forks in the road. Presumably, these positive experiences quickly change some “wiring” in the brain.

How do these rapid, positive transformations happen? It seems the brain has a way to facilitate accelerated change. And here’s where it gets really interesting: Psychedelic-assisted psychotherapy appears to tap into this natural neural mechanism.
Psychedelic-assisted psychotherapy

Those who’ve had a psychedelic experience usually describe it as a mental journey that’s impossible to put into words. However, it can be conceptualized as an altered state of consciousness with distortions of perception, modified sense of self and rapidly changing emotions. Presumably there is a relaxation of the higher brain control, which allows deeper brain thoughts and feelings to emerge into conscious awareness.


Psychedelic-assisted psychotherapy combines the psychology of talk therapy with the power of a psychedelic experience. Researchers have described cases in which subjects report profound, personally transformative experiences after one six-hour session with the psychedelic substance psilocybin, taken in conjunction with psychotherapy. For example, patients distressed about advancing cancer have quickly experienced relief and an unexpected acceptance of the approaching end. How does this happen?


Neuronal spines are the little bumps along the spreading branches of a neuron.
Patrick Pla via Wikimedia Commons, CC BY-SA


Research suggests that new skills, memories and attitudes are encoded in the brain by new connections between neurons – sort of like branches of trees growing toward each other. Neuroscientists even call the pattern of growth arborization.

Researchers using a technique called two-photon microscopy can observe this process in living cells by following the formation and regression of spines on the neurons. The spines are one half of the synapses that allow for communication between one neuron and another.

Scientists have thought that enduring spine formation could be established only with focused, repetitive mental energy. However, a lab at Yale recently documented rapid spine formation in the frontal cortex of mice after one dose of psilocybin. Researchers found that mice given the mushroom-derived drug had about a 10% increase in spine formation. These changes had occurred when examined one day after treatment and endured for over a month.




Tiny spines along a neuron’s branches are a crucial part of how one neuron receives a message from another. Edmund S. Higgins



A mechanism for psychedelic-induced change


Psychoactive molecules primarily change brain function through the receptors on the neural cells. The serotonin receptor 5HT, the one famously tweaked by antidepressants, comes in a variety of subtypes. Psychedelics such as DMT, the active chemical in the plant-based psychedelic ayahuasca, stimulate a receptor cell type, called 5-HT2A. This receptor also appears to mediate the hyperplastic states when a brain is changing quickly.

These 5-HT2A receptors that DMT activates are not only on the neuron cell surface but also inside the neuron. It’s only the 5-HT2A receptor inside the cell that facilitates rapid change in neuronal structure. Serotonin can’t get through the cell membrane, which is why people don’t hallucinate when taking antidepressants like Prozac or Zoloft. The psychedelics, on the other hand, slip through the cell’s exterior and tweak the 5-HT2A receptor, stimulating dendritic growth and increased spine formation.

Here’s where this story all comes together. In addition to being the active ingredient in ayahuasca, DMT is an endogenous molecule synthesized naturally in mammalian brains. As such, human neurons are capable of producing their own “psychedelic” molecule, although likely in tiny quantities. It’s possible the brain uses its own endogenous DMT as a tool for change – as when forming dendritic spines on neurons – to encode pivotal mental states. And it’s possible psychedelic-assisted psychotherapy uses this naturally occurring neural mechanism to facilitate healing.

A word of caution


In her essay collection “These Precious Days,” author Ann Patchett describes taking mushrooms with a friend who was struggling with pancreatic cancer. The friend had a mystical experience and came away feeling deeper connections to her family and friends. Patchett, on the other hand, said she spent eight hours “hacking up snakes in some pitch-black cauldron of lava at the center of the Earth.” It felt like death to her.

Psychedelics are powerful, and none of the classic psychedelic drugs, such as LSD, are approved yet for treatment. The U.S. Food and Drug Administration in 2019 did approve ketamine, in conjunction with an antidepressant, to treat depression in adults. Psychedelic-assisted psychotherapy with MDMA (often called ecstasy or molly) for PTSD and psilocybin for depression are in Phase 3 trials.


Edmund S. Higgins, Affiliate Associate Professor of Psychiatry & Family Medicine, Medical University of South Carolina

This article is republished from The Conversation under a Creative Commons license. Read the original article.


Is planting trees to combat climate change 'complete nonsense'?



Agence France-Presse
October 3, 2023 

Trees with the sun (Photo: jotily/Getty Images)

Bill Gates is emphatic: "I don't plant trees," he declared recently, wading into a debate about whether mass tree planting is really much use in fighting climate change.

The billionaire philanthropist was being probed on how he offsets his carbon emissions and insisted he avoids "some of the less proven approaches."

The claim that planting enough trees could solve the climate crisis is "complete nonsense", he told a climate discussion organised by the New York Times last week.

"Are we the science people or are we the idiots?"

Gates' polemical pronouncements made headlines and prompted criticism from backers of reforestation (planting trees in damaged forests) and afforestation (planting in areas that were not recently forest).

"I have dedicated the last 16 years of my life to making forests part of the climate solution," wrote Jad Daley, head of the American Forests NGO.

"This kind of commentary can really set us back," he said on X, formerly known as Twitter.

Mass tree planting schemes have been gaining ground for years as a way to suck carbon from the atmosphere at scale.

Even notoriously climate change-skeptical US Republicans have introduced legislation to support planting a trillion trees worldwide.

But Gates is far from alone in doubting the benefits of such ambitious plans.

A group of scientists warned on Tuesday that mass tree planting risks doing more harm than good, particularly in tropical regions.

That's primarily because it can replace complex ecosystems with monoculture plantations.

"Society has reduced the value of these ecosystems to just one metric -- carbon," the scientists from universities in Britain and South Africa wrote.

Carbon capture is "a small component of the pivotal ecological functions that tropical forests and grassy ecosystems perform," they said in an article in the Trends in Ecology and Evolution journal.

Jesus Aguirre Gutierrez, an author of the paper, pointed to examples in southern Mexico and Ghana, where once diverse forests "have now transformed into homogenous masses".

This makes them "highly vulnerable to diseases and negatively impacts local biodiversity," the senior researcher at the University of Oxford's Environmental Change Institute told AFP.

'Not just running around planting'

Major tree planting commitments often involve agroforestry or plantations, where the trees will eventually be felled, releasing carbon.

Reforestation projects often target areas that have been devastated by fires
 © Michael Dantas / AFP/File

And they are dominated by five tree species chosen largely for their timber and pulp value, or growth speed.

Among them is teak, which can overtake native species, "posing additional risks to native vegetation and the ecosystem", said Aguirre Gutierrez, who is also a Natural Environment Research Council fellow.

Other critiques include the lack of space globally for the many proposed mass planting projects and the risk of competition between smallholder agriculture and planting.

Misclassification of grassland and wetland as suitable for forest and planting poorly adapted or cared-for seedlings have also been problems highlighted by scientists.

So does planting trees really have no value?

Not so fast, says Daley, whose American Forests organization says it has planted 65 million trees.

It's Gates' premise that is wrong, Daley said.

"Literally no one is saying... that forests alone can save our environment," he told AFP.

He argues that critics ignore carefully calibrated projects involving native species in areas that need reforestation and focus instead on a few poorly conceived schemes.

"This broad brush critique has ignored the fact that much reforestation is driven by the loss of forests that won't regenerate without help."

"We are not just running around planting trees wherever we feel like it to capture carbon."

There are efforts to bridge the gap between critics and proponents, including 10 "golden rules for restoring forests", proposed by Britain's Royal Botanic Gardens, Kew and Botanic Gardens Conservation International.

They advise avoiding grasslands or wetlands, prioritising natural regeneration, and selecting resilient and biodiverse trees.

But they start with a rule that perhaps everyone can agree upon: protect existing forests first.

"It can take over 100 years for these forests to recover, so it is crucial that we protect what we already have before planting more."

© 2023 AFP
Commentary: Denial of climate change may be a party deal-breaker for young conservatives
2023/10/03

Left to right, Jaime Green, First Lady of Hawaii, Hawaii Governor Josh Green, President Joe Biden and First Lady Jill Biden visit an area devastated by wildfires in Lahaina, Hawaii on Aug. 21, 2023. 
- Mandel Ngan/AFP/GETTY IMAGES NORTH AMERICA/TNS

Benji Backer, a 25-year-old conservative from Wisconsin, was not pleased with a recent Republican presidential primary debate. The candidates either denied, ignored or downplayed the Fox moderator’s question on climate change.

Backer is not alone in his views. Founder of the American Conservation Coalition, Backer said of his peers: “Young people will never vote for a candidate that does not believe in climate change. We’re not going away; we are normalizing this as part of the Republican conversation. Republicans deserve to lose if they are climate deniers and don’t have a plan.”

Climate change is often seen as an intergenerational issue, with the younger generation expected to bear the brunt of the impacts. The GOP’s failure to articulate an adequate climate policy is alarming 18- to 38-year-old voters. The cost of inaction will have far-reaching consequences. Some young conservatives are concerned that their party’s reluctance to address climate change represents a failure to consider the interests of future generations.

The older conservative generations have broad influence and power over the current climate change narrative, though the time for change is ripe. And the time for climate denial and inaction has passed. The younger conservative generation isn’t buying the old narrative.

Young or old, we can see the escalating impact of drought, crop failure, wildfires, sea level rise and storm damage that will devastate future economic prosperity. The younger generations are coming of age and using their votes, which they demonstrated in record numbers in last year’s midterm election. Their votes could be crucial in swing states in 2024. They know that the problem is real, that it needs to be addressed now and that conservative policy solutions can make a difference.

GOP House Rep. John Curtis of Utah made a similar point to Backer’s. “I believe strongly that if Republicans don’t make (climate change) an issue, we will lose the upcoming generation of Republicans,” he said. “The upcoming generation will not be patient with us. This is a deal-breaker for them. They’ll leave the Republican Party over this one issue.”

Well-respected GOP pollster Frank Luntz said in 2019 that of all generations of current voters, “Three in four American voters want to see the government step in to limit carbon emissions — including a majority of Republicans (55%). Voters’ concerns simply aren’t being addressed.”

There are at least four reasons for young conservatives’ concern:

1. Scientific consensus: Older conservatives were educated in a time before climate science; younger generations learned climate science along with reading, writing and arithmetic. Education is foundational to our worldview. Advancing policies based on evidence and scientific consensus is crucial for effective solutions.

2. National security: Climate change is increasingly seen as a national security threat due to its potential to exacerbate conflicts over resources, disrupt supply chains and create refugee crises. Addressing climate change is a matter of protecting national security and maintaining geopolitical stability.

3. Economic opportunities: Renewable energy and other climate-friendly technologies represent economic opportunities, including job creation and innovation. Supporting policies that promote clean energy fosters economic growth and reduces reliance on foreign energy sources.

4. Conservative values: Some conservatives may argue that addressing climate change aligns with traditional conservative values, such as responsible stewardship of resources, fiscal responsibility, and a desire to preserve natural beauty and landscapes. Solutions that are pro-market and involve limited government regulation exist — such as a carbon fee and dividend with a border tax adjustment. We need to keep American businesses competitive in global markets.

Republicans should develop a coherent and effective climate policy before they cease to be a politically viable party. The political will is mounting for serious solutions to climate change as public opinion shifts.

Increasing numbers of Americans — including Republicans — are expressing concern and support for action. We need all voices at the solutions table, especially ones that reflect long-standing conservative principles.

____

ABOUT THE WRITER

Susan Atkinson is a volunteer for the Citizens Climate Lobby, an organization that reaches across the political spectrum to find common ground for climate change action.
This was probably John Kelly's 'final straw' with Trump: CNN's Jake Tapper
Matthew Chapman
October 3, 2023 

White House Chief of Staff John Kelly

Former President Donald Trump's one-time Chief of Staff and Secretary of Homeland Security John Kelly remained silent for years, both in and out of office, as his former boss attacked the troops — but he finally crossed a line that Kelly could no longer tolerate, said CNN's Jake Tapper on Tuesday.

This comes as Kelly is going public to confirm many of Trump's most controversial remarks disparaging servicemembers.

"Jake, the significance of this in normal times, former Chief of Staff coming out saying things on the record, is dramatic," said anchor Phil Mattingly. "In this past administration, so many people have come out and said so many things and confirmed lots of stuff. But this was different. John Kelly was different. Why?"

"I think what was the final straw for Kelly — and I've been talking to Kelly, I've known him for a long time, since before even he was the Department of Homeland Security Secretary," said Tapper. "And I think what — I'm assuming here. I'm interpreting. This is not a statement of fact. But I think if I may speculate, I think the statement about executing Mark Milley might have been the final straw for him."

"He's really been very upset about what Trump has been saying," Tapper continued. "Trump is disparaging of Gold Star families, disparaging of wounded veterans, disparaging of soldiers who gave their lives in World War I, has been very upsetting for him for years and years and years. But I think the comments about Mark Milley, who served his country honorably for 40 years, the threatening to execute him, and then, in Kelly's view, he thinks that Trump saying that publicly is basically a call to arms, a hope that one of Trump's followers will then take action against General Milley. And I think that probably is what pushed him over the edge to finally come forward and give this blistering commentary about what he thinks about Trump."

"When you read the comments — I mean, these are the comments of a patriot, of a soldier, of a Marine," added Tapper. "The comments of a conservative Republican. This is not him outflanking Trump on the left. But he is very, very disappointed."



 Trump supporters cheer execution threats against Milley: 'Why was he not before a firing squad?'

Travis Gettys
October 3, 2023 

NBC News

Donald Trump suggested that Gen. Mark Milley deserved execution for "treason," and the former president's fans heard his message loud and clear.

The ex-president – currently the GOP frontrunner – claimed last month the recently retired chairman of the Joint Chiefs of Staff would have faced death "in times gone by" for reassuring a Chinese general there were no plans to attack during the chaotic last days of Trump's administration, and supporters outside an Iowa campaign rally told NBC News they agreed.

“Treason is treason," said Trump supporter Vicky Entseminger. "There’s only one cure for treason: being put to death.”

Cynthia Yockey, a Trump supporter at his event in Ottumwa, told the network she was disappointed that Milley hadn't already been executed.

“Why was he not in there before a firing squad within a month?” Yockey said.

Some of the former president's fans thought his comments about Milley were inappropriate, but that hadn't shaken their support.

“It’s way too far, it’s way too far,” said Barbara Hadener, who voted for Trump in 2016 and 2020 and still plans to back him next year.

But most of the supporters who agreed to speak on camera agreed with Trump's comments about his former top military adviser.

“We used to execute or imprison people for all the treasonous actions I see,” said Rob Dannels, a registered Republican from Oskaloosa. “Now, in this day and age, it’s just throw it underneath the rug."



U.S. to recommend antibiotic pill after sex to prevent STIs

Agence France-Presse
October 3, 2023 

Doxycycline (Shutterstock)

Amid soaring rates of chlamydia, gonorrhea and syphilis, US health authorities on Monday proposed that doctors begin prescribing a common antibiotic as a pill taken after sex, despite concerns over fueling more resistant strains.

DoxyPEP, or doxycycline used as a post-exposure prophylaxis, was found to cut the risk of developing these infections in clinical trials involving men who have sex with men and transgender women who engaged in condomless sex.

Draft guidelines developed by the Centers for Disease Control and Prevention (CDC) accordingly target only these higher risk groups, out of concern a broader recommendation could drive the rise of superbugs.

"Innovation and creativity matter in public health, and more tools are desperately needed," Jonathan Mermin, who leads STI prevention at the CDC, told AFP ahead of the announcement.

The guidelines recommend a single 200 mg pill taken orally within 72 hours of a sexual encounter.

Reported cases of the three bacterial infections rose to 2.5 million in the United States in 2021, a further spike following about a decade of growth.

Several issues are behind the trend: fewer people are using condoms since the advent of PrEP -- daily pills that significantly reduce chances of contracting HIV.

Another potential driver of the spike is that people who are on PrEP are recommended to undergo health screenings every three months, likely increasing the identification of infections.

There is also the basic epidemiological fact that the greater the number of people infected, the more they can further infect.

Researchers have found DoxyPEP efficacious in three of four trials.

"What we found was there was about a two-thirds reduction in sexually transmitted infection every three months," Annie Luetkemeyer, who co-led a US trial, told AFP.

The physician-scientist at the University of California, San Francisco recruited some 500 people in San Francisco and Seattle among communities of men who have sex with men and transgender women.

The drug's efficacy was greatest against chlamydia and syphilis, both of which were reduced by about 80 percent, while for gonorrhea it was about 55 percent. There were few side effects.

Broadening access to doxycycline has prompted concerns about causing antibiotic resistance, particularly in gonorrhea, which is fast mutating. But early research hasn't found cause for alarm.

Connie Celum of the University of Washington, who co-led the US study, told AFP researchers that tested gonorrhea samples from breakthrough infections -- when people contracted the diseases despite taking the antibiotic -- in the DoxyPEP group and compared them to the group who didn't receive the pill.

Though they found the rate of resistant gonorrhea slightly higher in the DoxyPEP group, she said the finding could simply mean the pill is less effective against already resistant strains, rather than causing that resistance.

DoxyPEP could even boost better antibiotic practices.

If the preventative treatment were to slash gonorrhea cases by some 50 percent, it could reduce the number of people requiring antibiotic treatment with the current frontline treatment drug, ceftriaxone, whose efficacy which doctors are eager to preserve.

Longer term study is required, on both impacts on STIs but also "bystander" bacteria such as Staphylococcus aureus, which live inside people's noses but sometimes cause serious infections.
U$A
They still failed millions of children': Congress averted a shutdown, but not a childcare cliff

Jake Johnson, Common Dreams
October 3, 2023

Childcare (Shutterstock)

Congress temporarily averted a government shutdown with just hours to spare over the weekend after House Republicans finally agreed to pass a stopgap bill without the draconian spending cuts they had previously demanded.

But despite Senate Majority Leader Chuck Schumer's (D-N.Y.) invitation to the American public to " breathe a sigh of relief" following the measure's passage, one sector in particular had little reason to do so.

On Saturday, billions of dollars in emergency childcare funding approved during the coronavirus pandemic expired due to government inaction, a nightmare scenario that providers, lawmakers, and analysts had been warning about for months.

In mid-September, members of Congress introduced the Child Care Stabilization Act in a last-ditch effort to prevent catastrophe, but Republicans have not supported the bill.

As a result, according to a recent analysis by The Century Foundation, more than 3 million kids could soon lose their childcare spots, more than 70,000 childcare programs across the country could be forced to close their doors, and 232,000 childcare workers—who are chronically underpaid—will likely lose their jobs.

"While there is some temporary relief that the government avoided a shutdown last week, they still failed millions of children and families by not acting on the childcare cliff and failing to pass the Child Care Stabilization Act," Nicole Jorwic, chief of advocacy and campaigns at Caring Across Generations, said in a statement late Monday.

"The continuing gamesmanship in Congress is putting livelihoods at risk, and in a little more than a month from now, Congress will fail millions more if they continue down this path of threatening families' well-being and holding the economy hostage for political gain," said Jorwic. "Families all over this country are struggling as a direct result of the inaction from Congress. Our economy will not be able to fully recover and thrive if people who are already squeezed by the lack of investments in family-first policies have even more taken away. It is critical Congress stop manufacturing crises and instead, take care of their constituents."

"The loss of childcare resources will be devastating for families. For most, it can be their single largest cost."

The Covid-19 crisis hammered the childcare sector, which has been slower than other areas of the economy to recover after seeing significant job losses and other pandemic-related disruptions.

Tens of billions of dollars in childcare grants approved in 2021 as part of the American Rescue Plan provided some relief, helping to keep hundreds of thousands of childcare providers running and preventing millions of children from losing their spots.

Now that the funding has expired, many childcare centers are expected to raise tuition to compensate, potentially pushing low-income families out. Childcare costs vary across the U.S., but "prices are untenable for families even in lower-priced areas," warned a recent Labor Department analysis.

"Using the most recent data available from 2018 and adjusted for inflation to 2022 dollars, childcare prices range from $4,810 ($5,357 in 2022 dollars) for school-age home-based care in small counties to $15,417 ($17,171 in 2022 dollars) for infant center-based care in very large counties," the Labor Department found. "These prices represent between 8% and 19.3% of median family income per child."

The Century Foundation estimated that the impacts of the emergency funding lapse could cost U.S. families $9 billion a year in lost earnings, as many could have to leave the workforce or curb their hours to care for their children.

"Parents simply cannot afford to pay the true cost of providing care, and providers can't afford to earn any less," Daniel Hains, a managing director at the National Association for the Education of Young Children, toldThe New York Times.

The end of the childcare grants will compound the damage done by the collapse of the pandemic-era safety net, which lifted tens of millions out of poverty in 2021. The reversal has been sharp: Last year, U.S. child poverty more than doubled, largely due to the expiration of the boosted child tax credit that congressional Republicans and Sen. Joe Manchin (D-W.Va.) opposed.

In an op-ed for Fortune last week, All Our Kin CEO Jessica Sager warned that "the loss of childcare resources will be devastating for families. For most, it can be their single largest cost. And without it, they cannot participate fully in the workforce."

"In Arkansas, Montana, Utah, Virginia, West Virginia, and Washington, D.C., the impact could be particularly drastic, with some estimates saying at least half of the licensed childcare programs could close," Sager wrote. "Another 14 states could see their options for licensed childcare programs reduced by a third."
'As un-Christian as it gets': Conservative wallops evangelicals for 'worship' of Trump

Brad Reed
October 3, 2023 

MIAMI, FLORIDA - JANUARY 03: Catherine Castillo prays during the 'Evangelicals for Trump' campaign event held at the King Jesus International Ministry as they await the arrival of President Donald Trump on January 03, 2020 in Miami, Florida. The rally was announced after a December editorial published in Christianity Today called for the President Trump's removal from office.
 (Photo by Joe Raedle/Getty Images)


Conservative columnist Matt Lewis has written a new piece for The Daily Beast where he hammers American evangelicals for "worshipping" former President Donald Trump, an act which he describes as "un-Christian as it gets."

Lewis begins his piece by marveling at the way many American evangelicals feel beholden to Trump despite the fact that his allegedly un-Christlike behavior has led to him getting indicted in four different jurisdictions on 91 felony counts.

However, notes Lewis, many evangelicals have rationalized this by claiming that God personally told them that He wants Trump to lead America.

"Never mind the humiliation that pro-Trump prophets have faced for prophesying he would win in 2020—and then that, despite losing, he would be reinstated in 2021," he argues. "There is a real sense among many Christians (whether this 'word of knowledge' came directly from the man upstairs, or was shared second hand) that Trump is still God’s vessel in 2024."

Lewis, who himself is an evangelical Christian, then zeroes in on the theological issue he has with so many of his fellow evangelicals have with emphasizing belief in prophecy.

"The notion that Trump could be an imperfect vessel ordained to do God’s will (see Cyrus or King David) is not without precedent," argues Lewis. "Then again, that projection could also be applied to any political leader... Just as slaveholders cited scripture to baptize an evil institution, one could cite this scripture to argue that any current political leader, no matter how tyrannical, is ordained by God. By this logic, criticizing Biden (or anyone in power) is sinful."