Cancer-causing chemicals detected in toys and headphones

Peer-Reviewed Publication

GREEN SCIENCE POLICY INSTITUTE

Cancer-causing chlorinated paraffins are still used in a wide range of everyday products sold in North America despite their known health harm and being banned in Canada for a decade, according to a new peer-reviewed study in Environmental Science: Processes & Impacts. The researchers detected short-chain chlorinated paraffins in more than 85 percent of products tested, including headphones, plastic toys, clothing, personal care products, and indoor paints purchased in Canada.

“We were astonished to find chlorinated paraffins in these types of products. Any parent would shudder at the thought of their baby chewing on a toy filled with cancer-causing chemicals,” said co-author Hui Peng, an Assistant Professor of Chemistry at the University of Toronto. “We need to protect our children and the wider public from these harmful substances.” 

Short-chain chlorinated paraffins cause cancer in laboratory rats and mice–specifically targeting the liver, thyroid, and kidney. Though there are no human studies, the International Agency for Research on Cancer classifies them as possible human carcinogens. They also build up in our bodies, food webs, and environment. 

In 2012, the Government of Canada determined that “all chlorinated paraffins are considered harmful with respect to human health” and banned their manufacture, new use, and import. In 2017, short-chain chlorinated paraffins were listed for elimination under the Stockholm Convention on Persistent Organic Pollutants.

Nonetheless, their total global production is huge– more than 1 million tons per year– and is increasing.  These toxic chemicals are used in everyday products as flame retardants, plasticizers and lubricants. Until now, many of their specific uses in products were not known to scientists and the public. 

The highest concentrations of chlorinated paraffins in this study were detected in headphones and computer wires. The next highest concentrations were in toys and toy packaging. These uses can lead to human exposure through direct hand contact, mouthing of products by young children, and through contaminated dust making its way from hands to mouths. 

Since the tested products were largely manufactured for an international market, chlorinated paraffins are likely also found in similar products in the U.S., Europe, and beyond.

“Chlorinated paraffins are very harmful and widespread in everyday products, but they are flying under the radar,” said co-author Arlene Blum, executive director of the Green Science Policy Institute. “Many of their uses are unnecessary and should be stopped immediately for healthier people and ecosystems.”

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JOURNAL

Environmental Science Processes & Impacts

DOI

10.1039/D2EM00494A 

ARTICLE TITLE

Widespread presence of chlorinated paraffins in consumer products

ARTICLE PUBLICATION DATE

11-Apr-2023

New findings that map the universe’s cosmic growth support Einstein’s theory of gravity

Research by the Atacama Cosmology Telescope collaboration has culminated in a significant breakthrough in understanding the evolution of the universe.

Reports and Proceedings

PRINCETON UNIVERSITY

 

IMAGE: RESEARCHERS USED THE ATACAMA COSMOLOGY TELESCOPE TO CREATE THIS NEW MAP OF THE DARK MATTER. THE ORANGE REGIONS SHOW WHERE THERE IS MORE MASS; PURPLE WHERE THERE IS LESS OR NONE. THE TYPICAL FEATURES ARE HUNDREDS OF MILLIONS OF LIGHT YEARS ACROSS. THE WHITISH BAND SHOWS WHERE CONTAMINATING LIGHT FROM DUST IN OUR MILKY WAY GALAXY, MEASURED BY THE PLANCK SATELLITE, OBSCURES A DEEPER VIEW. THE NEW MAP USES LIGHT FROM THE COSMIC MICROWAVE BACKGROUND (CMB) ESSENTIALLY AS A BACKLIGHT TO SILHOUETTE ALL THE MATTER BETWEEN US AND THE BIG BANG. “IT’S A BIT LIKE SILHOUETTING, BUT INSTEAD OF JUST HAVING BLACK IN THE SILHOUETTE, YOU HAVE TEXTURE AND LUMPS OF DARK MATTER, AS IF THE LIGHT WERE STREAMING THROUGH A FABRIC CURTAIN THAT HAD LOTS OF KNOTS AND BUMPS IN IT,” SAID SUZANNE STAGGS, DIRECTOR OF ACT AND PRINCETON'S HENRY DEWOLF SMYTH PROFESSOR OF PHYSICS. “THE FAMOUS BLUE AND YELLOW CMB IMAGE IS A SNAPSHOT OF WHAT THE UNIVERSE WAS LIKE IN A SINGLE EPOCH, ABOUT 13 BILLION YEARS AGO, AND NOW THIS IS GIVING US THE INFORMATION ABOUT ALL THE EPOCHS SINCE.” view more 

CREDIT: ACT COLLABORATION

For millennia, humans have been fascinated by the mysteries of the cosmos.

Unlike ancient philosophers imagining the universe’s origins, modern cosmologists use quantitative tools to gain insights into the universe’s evolution and structure. Modern cosmology dates back to the early 20th century, with the development of Albert Einstein’s theory of general relativity.

Now, researchers from the Atacama Cosmology Telescope (ACT) collaboration have created a groundbreaking new image that reveals the most detailed map of dark matter distributed across a quarter of the entire sky, extending deep into the cosmos. What’s more, it confirms Einstein’s theory of how massive structures grow and bend light, over the entire 14-billion-year life span of the universe. 

“We have mapped the invisible dark matter across the sky to the largest distances, and clearly see features of this invisible world that are hundreds of millions of light-years across, says Blake Sherwin, professor of cosmology at the University of Cambridge, where he leads a group of ACT researchers. “It looks just as our theories predict.”

Despite making up 85% of the universe and influencing its evolution, dark matter has been hard to detect because it doesn’t interact with light or other forms of electromagnetic radiation. As far as we know dark matter only interacts with gravity. 

To track it down, the more than 160 collaborators who have built and gathered data from the National Science Foundation’s Atacama Cosmology Telescope in the high Chilean Andes observe light emanating following the dawn of the universe’s formation, the Big Bang—when the universe was only 380,000 years old. Cosmologists often refer to this diffuse light that fills our entire universe as the “baby picture of the universe,” but formally, it is known as the cosmic microwave background radiation (CMB).

The team tracks how the gravitational pull of large, heavy structures including dark matter warps the CMB on its 14-billion-year journey to us, like how a magnifying glass bends light as it passes through its lens.

“We’ve made a new mass map using distortions of light left over from the Big Bang,” says Mathew Madhavacheril, assistant professor in the Department of Physics and Astronomy at the University of Pennsylvania. “Remarkably, it provides measurements that show that both the ‘lumpiness’ of the universe, and the rate at which it is growing after 14 billion years of evolution, are just what you’d expect from our standard model of cosmology based on Einstein's theory of gravity.” 

Sherwin adds, “our results also provide new insights into an ongoing debate some have called ‘The Crisis in Cosmology,’”explaining that this crisis stems from recent measurements that use a different background light, one emitted from stars in galaxies rather than the CMB. These have produced results that suggest the dark matter was not lumpy enough under the standard model of cosmology and led to concerns that the model may be broken. However, the team’s latest results from ACT were able to precisely assess that the vast lumps seen in this image are the exact right size. 

“When I first saw them, our measurements were in such good agreement with the underlying theory that it took me a moment to process the results,” says Cambridge Ph.D. student Frank Qu, part of the research team. “It will be interesting to see how this possible discrepancy between different measurements will be resolved.”

“The CMB lensing data rivals more conventional surveys of the visible light from galaxies in their ability to trace the sum of what is out there,” says Suzanne Staggs, director of ACT and Henry DeWolf Smyth Professor of Physics at Princeton University. “Together, the CMB lensing and the best optical surveys are clarifying the evolution of all the mass in the universe.” 

“When we proposed this experiment in 2003, we had no idea the full extent of information that could be extracted from our telescope,” says Mark Devlin, the Reese Flower Professor of Astronomy at the University of Pennsylvania and the deputy director of ACT. “We owe this to the cleverness of the theorists, the many people who built new instruments to make our telescope more sensitive, and the new analysis techniques our team came up with.”

ACT, which operated for 15 years, was decommissioned in September 2022. Nevertheless, more papers presenting results from the final set of observations are expected to be submitted soon, and the Simons Observatory will conduct future observations at the same site, with a new telescope slated to begin operations in 2024. This new instrument will be capable of mapping the sky almost 10 times faster than ACT.

The Atacama Cosmology Telescope in Northern Chile, supported by the National Science Foundation, operated from 2007-2022. The project is led by Princeton University and the University of Pennsylvania -- Director Suzanne Staggs at Princeton, Deputy Director Mark Devlin at Penn -- with 160 collaborators at 47 institutions.

CREDIT

Mark Devlin, Deputy Director of the Atacama Cosmology Telescope and the Reese Flower Professor of Astronomy at the University of Pennsylvania

Research by the Atacama Cosmology Telescope collaboration has culminated in a groundbreaking new map of dark matter distributed across a quarter of the entire sky, reaching deep into the cosmos. Findings provide further support to Einstein’s theory of general relativity, which has been the foundation of the standard model of cosmology for more than a century, and offer new methods to demystify dark matter.

CREDIT

Debra Kellner

Research by the Atacama Cosmology Telescope collaboration has culminated in a groundbreaking new map of dark matter distributed across a quarter of the entire sky, reaching deep into the cosmos. Findings provide further support to Einstein’s theory of general relativity, which has been the foundation of the standard model of cosmology for more than a century, and offer new methods to demystify dark matter.

CREDIT

Lucy Reading-Ikkanda, Simons Foundation

Learn more at https://act.princeton.edu/. This research will be presented at "Future Science with CMB x LSS," a conference running from April 10-14 at Yukawa Institute for Theoretical Physics, Kyoto University. This work was supported by the U.S. National Science Foundation (AST-0408698, AST-0965625 and AST-1440226 for the ACT project, as well as awards PHY-0355328, PHY-0855887 and PHY-1214379), Princeton University, the University of Pennsylvania, and a Canada Foundation for Innovation award. Team members at the University of Cambridge were supported by the European Research Council.

From National Magazine Award-winning writer Richard Conniff: "Ending Epidemics: A History of Escape from Contagion"

How scientists saved humanity from the deadliest infectious diseases— and what we can do to prepare ourselves for future epidemics.

Book Announcement

THE MIT PRESS

 

IMAGE: COVER ART TO ENDING EPIDEMICS. view more 

CREDIT: THE MIT PRESS. 2023.

How scientists saved humanity from the deadliest infectious diseases—and what we can do to prepare ourselves for future epidemics.

After the unprecedented events of the COVID-19 pandemic, it may be hard to imagine a time not so long ago when deadly diseases were a routine part of life. It is harder still to fathom that the best medical thinking at that time blamed
these diseases on noxious miasmas, bodily humors, and divine dyspepsia. This all began to change on a day in April 1676, when a little-known Dutch merchant described bacteria for the first time. Beginning on that day in Delft and ending on the day in 1978 when the smallpox virus claimed its last known victim, Ending Epidemics explains how we came to understand and prevent many of our worst infectious diseases—and double average life expectancy.

Ending Epidemics tells the story behind “the mortality revolution,” the dramatic transformation not just in our longevity, but in the character of childhood, family life, and human society. Richard Conniff recounts the moments of inspiration and innovation, decades of dogged persistence, and, of course, periods of terrible suffering that stir individuals, institutions, and governments to act in the name of public health. Stars of medical science feature in this drama, but lesser-known figures also play a critical role. And while the history of germ theory is central to this story, Ending Epidemics also describes the
importance of everything from sanitation improvements and the discovery of antibiotics to the development of the microscope and the syringe—technologies we now take for granted.

Richard Conniff is a National Magazine Award-winning writer for Smithsonian magazine, The Atlantic, National Geographic, and other publications, and a past Guggenheim Fellow. Among his many books are The Species Seekers: Heroes, Fools, and the Mad Pursuit of Life on Earth; Swimming with Piranhas at Feeding Time: My Life Doing Dumb Stuff with Animals; The Natural History of the Rich: A Field Guide; and, most recently, House of Lost Worlds: Dinosaurs, Dynasties, and the Story of Life on Earth. Conniff has been a commentator on NPR's Marketplace and a contributing opinion writer for the New York Times.

Some interesting facts taken from the book:
• Infectious disease prevention is the main reason our average lifespan has doubled since the 1800s. This is, as one historian recently put it, “arguably the most important single historical change of the last two hundred years,” and also the least recognized.

• The catch-22 of vaccines and, in truth, of all infectious disease discoveries is that they save us from diseases—and then cause us to forget the diseases from which they have saved us. And when we forget, we become casual about prevention.

• Two women, Pearl Kendrick and Grace Eldering, underpaid, working in their spare time, and in the face of skepticism from male counterparts, developed the first successful vaccine against whooping cough, a disease that was then killing 4000 American children on average per year. Their work has largely been forgotten—but it continues to save tens of thousands of lives a year.

• The original description of a bacteria and a virus—the two leading causes of infectious disease—both occurred, at an interval of 200 years, in Delft, a small Dutch city otherwise best known as the home of Johannes Vermeer.

• The campaign against infectious disease isn’t just about developed nations, nor is it just a story in the past tense. In recent decades, global public health programs have boosted uptake of six basic childhood vaccines from less than 5 percent of children in many countries to 86 percent or better in almost all countries, with a corresponding reduction in disease.
 

Endorsements:

“A taut interrogation of the centuries of labor that protected us from pathogens, a bitter lament for how
quickly we abandoned our awareness of risk, and a stirring call for a new generation of disease fighters
to take up the battle. Ending Epidemics drives home the post-COVID lesson of the peril of
complacency.”--Maryn McKenna, author of Big Chicken, Superbug and Beating Back the Devil; Senior Fellow, Center
for the Study of Human Health, Emory University

“Ending Epidemics is an important book, deeply and lovingly researched, written with precision and
elegance, a sweeping story of centuries of human battle with infectious disease. Conniff is a brilliant
historian with a jeweler's eye for detail. I think the book is a masterpiece.”--Richard Preston, author of The Hot Zone and The Demon in the Freezer

“A timely and highly readable account of humanity's struggles and progress in the fight against
infectious disease. Set across three centuries, from the birth of immunology to the antibiotic revolution,
Conniff draws on the personal stories behind these great medical and scientific leaps. A fascinating
read with powerful lessons for tackling today's—and indeed future—epidemics.”--Peter Piot, Former Director and Handa Professor of Global Health, London School of Hygiene & Tropical Medicine; author of No Time to Lose and AIDS: Between Science and Politics

“A dramatic, page-turning account of the grim, never-ending war waged by infections on humankind.
And how we fought back, sometimes successfully, sometimes not.”--Paul A. Offit, Professor of Pediatrics, Children's Hospital of Philadelphia; author of You Bet Your Life: From Blood Transfusions to Mass Vaccinations, the Long and Risky History of Medical Innovation

Unique statewide survey provides insight into cancer-related knowledge, beliefs and behaviors of Hispanic residents

Analysis provides guidance for future tailored cancer screening messaging and prevention strategies

Peer-Reviewed Publication

REGENSTRIEF INSTITUTE

INDIANAPOLIS – Cancer is the leading cause of death for Hispanics in the U.S. and in the state of Indiana. Funded by the Indiana University Melvin and Bren Simon Comprehensive Cancer Center, a survey of adult Hispanic Indiana residents, conducted by researchers from Regenstrief Institute and Indiana University, presents a snapshot of Hispanics' cancer-related knowledge, beliefs and behaviors, providing guidance for the future development of tailored cancer screening messaging and prevention strategies.

Several survey findings were unexpected, and the researchers believe merit further exploration. These include:  

• Urban and rural Hispanic residents did not differ in their cancer knowledge, beliefs or behaviors. 
• U.S.-born Hispanic individuals with higher income and education more often believed they were likely to develop cancer and to worry about getting cancer. 
• While educational level was positively associated with knowledge, it did not correlate with adherence to screening guidelines, with the exception of cervical cancer. 
• Most survey respondents were unable to accurately identify ages to begin screening for breast, colorectal, or lung cancer, which also has been observed in non-Hispanic populations. 

“Our findings could help guide both future research and public health outreach targeting high-risk groups, in this case Hispanics,” said Regenstrief Institute Center for Health Services Research Director David Haggstrom, M.D., MAS, corresponding and senior author of the new study. “We want to reach all age groups in the Hispanic community with cancer screening approaches to reduce the burden of disease. Given that cancer is of greater incidence and prevalence among older individuals, this is an audience that we especially want to learn more about, so we can promote cancer screening among them.”

The average age of the Hispanic population surveyed was 53 years. Approximately 11 percent of respondents self-identified as Indigenous or Mestizo, 6 percent as multi-racial and 1.5 percent as Black. Approximately 52 percent of survey respondents were male.

The online survey was conducted during the height of the COVID-19 pandemic, which presented in-person recruitment challenges. Prospective survey respondents were recruited via television, social media outreach and the Facebook pages of Hispanic community organizations.

“Using non-traditional approaches, we tapped into a lot of different groups that make up the Hispanic community including first- and second-generation immigrants, a wide distribution of income, education and ages as well as representatives of the approximately one fourth of the Hispanic population that does not appear in usual sampling frameworks like driver’s license lists,” said study co-author Gerardo Maupomé, BDS, MSc, PhD. “Conducting this survey was particularly challenging because we knew that many in the Hispanic community would not be easy to find unless you knew how to get ahold of them.

“Collecting data from hard-to-reach populations within the Hispanic community, we expanded considerably the body of knowledge about what are the risk factors and the beliefs and the behaviors that modify cancer experience.”

Approximately half of the 1,520 respondents completed the survey in Spanish. Survey takers identified their nation of birth as United States (60 percent); Mexico (14 percent), Cuba (7 percent), Puerto Rico (6 percent) or another country (13 percent).

“Hispanics residing in Indiana are somewhat representative of Hispanics residing in the Midwest, although not necessarily representative of Hispanics residing in other areas of the United States due, in part, to variation in immigration patterns,” said Dr. Haggstrom. “To our knowledge, this is the only data collection and analysis of Hispanics residing in the Midwest that enables drilling down on the associations in this population of knowledge and beliefs with behaviors.”

Dr. Maupomé added, “the Midwest and the South have in the past 10 to 15 years become what is called a gateway destination. The number of recent Hispanic arrivals is noticeable because there were not that many to begin with. What we’ve seen in our study of Indiana is the fine-grained stages of the trajectory of integration that occur, distinct from the traditional Hispanic areas of the U.S. – e.g., Southern California, Texas and Florida.”

This study was funded by the Indiana University Melvin and Bren Simon Comprehensive Cancer Center.

“Cancer-related knowledge, beliefs, and behaviors among Hispanic/Latino residents of Indiana” is published in Cancer Medicine. 

Authors:

Manuel R. Espinoza-Gutarra 1, Susan M. Rawl 2 3, Gerardo Maupome 4, Heather A. O'Leary 5, Robin E. Valenzuela 6, Caeli Malloy 3, Lilian Golzarri-Arroyo 7, Erik Parker 7, Laura Haunert 3 8, and David A. Haggstrom 9 10 11. 

Affiliations:

1Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA. 

2Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA. 

3Indiana University School of Nursing, Indianapolis, Indiana, USA. 

4Indiana University Purdue University Indianapolis, Richard M. Fairbanks School of Public Health, Indianapolis, Indiana, USA. 

5Northeast Ohio Medical University, Rootstown, Ohio, USA. 

6Indiana University Purdue University Fort Wayne, Fort Wayne, Indiana, USA. 

7School of Public Health, Indiana University Bloomington, Bloomington, Indiana, USA. 

8Indiana University School of Medicine, Indianapolis, Indiana, USA. 

9Center for Health Services Research, Regenstrief Institute, Indianapolis, Indiana, USA. 

10VA HSR&D Center for Health Information and Communication, Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana, USA. 

11Division of General Internal Medicine and Geriatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.

About David A. Haggstrom, M.D., MAS

In addition to his role as director of the Regenstrief Institute’s Center for Health Services Research, David A. Haggstrom, M.D., MAS, is a core investigator for the U.S. Department of Veterans Affairs Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center. He is also Sam Regenstrief Scholar in Health Sciences Research and an associate professor of medicine at Indiana University School of Medicine and a member of the Indiana University Melvin and Bren Simon Comprehensive Cancer Center.

About Gerardo Maupomé, BDS, MSc, PhD

Gerardo Maupomé, BDS, MSc, PhD, is associate dean of research at IU Richard M. Fairbanks School of Public Health and a Regenstrief Institute Affiliated Scientist. He is associate director of the Community Health Partnership program within the Indiana Clinical and Translational Sciences Institute. He has been recognized as a leader in the Hispanic community by La Plaza, Inc. and the Indiana Latino Institute, the largest Hispanic community organization in Indiana.

About Regenstrief Institute

Founded in 1969 in Indianapolis, the Regenstrief Institute is a local, national and global leader dedicated to a world where better information empowers people to end disease and realize true health. A key research partner to Indiana University, Regenstrief and its research scientists are responsible for a growing number of major healthcare innovations and studies. Examples range from the development of global health information technology standards that enable the use and interoperability of electronic health records to improving patient-physician communications, to creating models of care that inform practice and improve the lives of patients around the globe.

Sam Regenstrief, a nationally successful entrepreneur from Connersville, Indiana, founded the institute with the goal of making healthcare more efficient and accessible for everyone. His vision continues to guide the institute’s research mission.

About IU School of Medicine
IU School of Medicine is the largest medical school in the U.S. and is annually ranked among the top medical schools in the nation by U.S. News & World Report. The school offers high-quality medical education, access to leading medical research and rich campus life in nine Indiana cities, including rural and urban locations consistently recognized for livability.

About Richard M. Fairbanks School of Public Health 
Located on the IUPUI and Fort Wayne campuses, the IU Richard M. Fairbanks School of Public Health is committed to advancing the public’s health and well-being through education, innovation and leadership. The Fairbanks School of Public Health is known for its expertise in biostatistics, epidemiology, cancer research, community health, environmental public health, global health, health policy and health services administration. 

 

 

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JOURNAL

Cancer Medicine

DOI

10.1002/cam4.5466 

ARTICLE TITLE

Cancer-related knowledge, beliefs, and behaviors among Hispanic/Latino residents of Indiana

Diverse teams survive longer when facing environmental changes

Peer-Reviewed Publication

CARNEGIE MELLON UNIVERSITY

As business ventures grow, they must navigate the opportunities and challenges presented by environmental changes. In a new study, researchers examined the interplay of environmental change and the internal and external conditions governing a venture’s founding. For businesses founded in dynamic environments, they found that assembling more functionally diverse founding teams lead to longer survival when facing increasingly uncertain environments, while functionally homogeneous teams — those with relatively few distinct roles and viewpoints — do better when environments become more predictable.

The study was conducted by researchers at Carnegie Mellon University (CMU), Stanford University, and INSEAD. It is published in the Strategic Entrepreneurship Journal in a special issue entitled “Environmental Change, Strategic Entrepreneurial Action, and Success.”

“Predicting the course of environmental change is difficult, but entrepreneurs who can synchronize their predictions with their decisions about team composition perform better,” suggests D. Carrington Motley, Entrepreneurship Instructor at CMU’s Tepper School of Business, who led the study.

Prior studies on the effect of environmental change on business ventures have examined the role of the impact of recent events. They have not explored how the relationship between recent environmental change and performance outcomes depends on ventures’ past, including environmental conditions when the firm was founded.

“If environmental conditions at founding have a lasting influence on ventures’ internal processes, and recent environmental conditions determine the effectiveness of these processes, it is crucial for our theories of environmental change to account for both periods,” explains Charles E. Eesley, Associate Professor of Management Science and Engineering at Stanford, who coauthored the study.

To address this matter, the study integrated research on the persistence of founding conditions with research on the effects of environmental change. Researchers surveyed more than 140,000 Stanford University alumni to produce a dataset of more than 1,000 entrepreneurs who founded ventures between 1960 and 2011; the ventures represented 19 industries, from agriculture to energy and utilities. Respondents’ self-reported data were verified by cross referencing their information with lists of public and private companies.

The survey assessed the length of time ventures survived and whether ventures achieved positive liquidity events (e.g., underwent an observed initial public offering or a merger or acquisition). It also asked founders about the functional roles present on their founding teams (e.g., sales and marketing, general administration, operations, finance).

Teams that are functionally diverse have members who occupy a range of roles and have a broader focus, attending to such areas as sales, marketing, manufacturing, and distribution. They also seek out and exchange large amounts of information and debate a wide range of perspectives because many viewpoints are represented.

The interaction of high environmental dynamism — the degree to which environmental changes are unpredictable for firms’ decision makers — at founding and a functionally diverse founding team helped ventures survive longer when environmental dynamism increased over the lifetime of the venture, the study found. However, the same founding conditions resulted in a decreased likelihood of positive exit when environmental dynamism increased over the lifetime of the venture.

Among the study’s limitations, the authors note that ventures created by Stanford alumni may not be representative of ventures in general. Also, data were collected at one point in time and thus did not follow the ventures contemporaneously. Finally, based on the data used, the study produced only indirect evidence of the relationship between the environmental dynamism at founding and a venture’s internal processes.

“Our findings highlight the importance of firms developing capabilities to enable flexibility in decision-making processes, which are often inflexible, which limits firms’ ability to take advantage of unique opportunities provided by environmental change,” notes Wesley Koo, Assistant Professor of Strategy, who coauthored the study.

The research was funded by Sequoia Capital, the Kauffman Foundation, Stanford University School of Engineering, and the Stanford Technology Ventures Program.

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JOURNAL

Strategic Entrepreneurship Journal

DOI

10.1002/sej.1461 

ARTICLE TITLE

Born into chaos: How founding conditions shape whether ventures survive or thrive when experiencing environmental change

Understanding a community’s shared vision for public health is key to supporting change

Research published in the Journal of Nutrition Education and Behavior explores how social norms and culture influence food preferences, physical activity behaviors and future hopes for community development

Peer-Reviewed Publication

ELSEVIER

 

AUDIO: CORRESPONDING AUTHOR CATHERINE E. SANDERS, PHD, DISCUSSES THE RESULTS OF CDC’S HIGH OBESITY PROGRAM IMPLEMENTED IN FIVE RURAL SOUTHERN COUNTIES BY THE UNIVERSITY OF GEORGIA. RESEARCHERS IDENTIFY THE CHALLENGES OF AND SOLUTIONS FOR ADDRESSING HEALTHY EATING AND PHYSICAL ACTIVITY PRACTICES IN COMMUNITIES WHERE THOSE PRACTICES COUNTER CULTURAL NORMS. view more 

CREDIT: JOURNAL OF NUTRITION EDUCATION AND BEHAVIOR

Philadelphia, April 11, 2023 – The prevalence of obesity in rural communities goes beyond food choice and geography to include issues such as class, culture and identity; however, these issues are often not taken into account in policy, systems and environmental (PSE) change programs developed for community members. This study in the Journal of Nutrition Education and Behavior, published by Elsevier, explores the influence of factors beyond food and fitness, such as race relations, generational influences, physical activity social norms, and shared community goals with regard to PSE initiatives.

"Culture is a really big part of history and history is a really big part of rural communities. So, we wanted to examine the relationship between lack of access from the built environment as well as how culture and cultural identity interact," says corresponding author Catherine E. Sanders, PhD, currently Assistant Professor and Extension Specialist of Food Systems Communication at North Carolina State University. "Cultural differences and expectations, including norms around physical activity and body size, may influence obesity prevalence and effectiveness of programs implemented by health professionals."

The research was conducted by Dr. Sanders during her doctoral program at the University of Georgia in the Department of Agricultural Leadership, Education and Communication along with co-investigators Alexa Lamm, PhD, Alison Berg, PhD, RDN, LD, and Nekeisha Randall, MAL.

Researchers looked at data from a Centers for Disease Control and Prevention (CDC) funded project, Healthier Together, where university and coalition members used grant funding to create shared-use community gardens, work with food pantries for greater access to healthy food options, install grab and go coolers, and build walking trails to encourage physical activity. The project was the result of a partnership between the University of Georgia Colleges of Public Health, Agricultural and Environmental Sciences, Family and Consumer Sciences, and Environment and Design as well as UGA Extension. This PSE project was started in 2018 in five rural counties in Georgia where adult obesity prevalence exceeds 40%. The research team interviewed 39 community coalition members who were instrumental in implementing the project in these counties.

Key themes emerging from the study include:

• The challenge of addressing healthy eating and physical activity practices in communities where those practices counter cultural norms.
• The impact of food availability on communities where grocery stores with less healthy but more affordable options are prevalent.
• The importance of relationship building in collective action. Participants cited improvements in community cohesion and shared goals from those of different backgrounds and cultures through their involvement in the Healthier Together project.

"Overall, community coalition members just wanted people to see value in the change initiative. They wanted to lower obesity rates, but some of the interesting findings related to culture included the slowness of change and how rural communities should help us qualify successes. They recognized you're not going to come in and have change overnight because of community traditions," states Sanders. "Knowing the strong influence that culture has on food choice and physical activity, health practitioners should be encouraged to create interventions in alignment with the cultural norms of the communities they serve. Working with this in mind will help create more effective and sustainable programs with long-term success."

 

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JOURNAL

Journal of Nutrition Education and Behavior

DOI

10.1016/j.jneb.2022.10.011 

METHOD OF RESEARCH

Data/statistical analysis

SUBJECT OF RESEARCH

People

ARTICLE TITLE

Qualitative Exploration of Cultural Influence on a Rural Health-Promotion Initiative

Stopping storms from creating dangerous urban geysers

Expelled from sewer systems during intense rainstorms, massive water jets can cause significant flooding and damage

Peer-Reviewed Publication

AMERICAN INSTITUTE OF PHYSICS

 

IMAGE: SIMULATION OF A STORM GEYSER LIFE CYCLE. view more 

CREDIT: LI ET AL.

WASHINGTON, April 11, 2023 – During intense rainstorms, residents of urban areas rely on stormwater sewers to keep streets and homes from flooding. But in some cases, air pockets in sewers combine with fast-moving water to produce waterspouts that can reach dozens of feet high and last for several minutes. These so-called storm geysers can flood the surrounding area, cause damage to nearby structures, injure bystanders, and compromise drainage pipes.

In Physics of Fluids, by AIP Publishing, researchers from Sichuan University, Ningbo University, University of Alberta, and Hohai University developed a computational model of stormwater piping to study storm geysers. They used this model to understand why storm geysers form, what conditions tend to make them worse, and what city planners can do to prevent them from occurring.

Perhaps the biggest cause of storm geysers is poor city planning. With extreme weather events becoming more common due to climate change, cities can often find themselves unprepared for massive amounts of rain. Growing cities are especially vulnerable. Small cities have small drainage pipes, but new streets and neighborhoods result in added runoff, and those small pipes may not be able to handle the increased volume.

“This can lead to pressurized flow and the potential for air pockets to become entrapped and transported through the pipeline,” said author Jianmin Zhang, of Sichuan University. “These air pockets can ultimately be discharged through maintenance holes, resulting in storm geysers.”

The authors say the best cure for a storm geyser is bigger pipes.

“The most effective preventive measure for newly planned drainage pipelines is to increase the pipeline diameter and improve system design, which reduces the likelihood of full-flow conditions and eliminates storm geysers,” said Zhang.

However, that advice is little help to cities with existing pipeline infrastructure. In these systems, the focus must be on minimizing the potential damage by reducing the height of the geysers, the volume of expelled water, or the resulting damage to the pipeline.

“Scholars have proposed prevention measures such as increasing the maintenance hole diameter, using expansion segments in maintenance holes, installing orifice plates, and adding structures to allow air release while preventing the outflow of water,” said Zhang. “However, these measures often cannot achieve all of the aforementioned objectives simultaneously.”

While their model provides substantial guidance to city planners, the team hopes to expand their work to evaluate a range of prevention measures and identify the best overall solutions.

“We plan to systematically evaluate existing prevention measures that have received significant attention from scholars, analyze their advantages and disadvantages, and propose a comprehensive measure that achieves optimal results,” said Zhang. “Our ultimate goal is to apply this comprehensive approach in practical engineering applications to eliminate storm geysers.”

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The article “Modeling geysers triggered by an air pocket migrating with running water in a pipeline” is authored by Xin Li, Jianmin Zhang, David Z. Zhu, and Shangtuo Qian. It will appear in Physics of Fluids on April 11, 2023 (DOI: 10.1063/5.0138342). After that date, it can be accessed at https://doi.org/10.1063/5.0138342.

ABOUT THE JOURNAL

Physics of Fluids is devoted to the publication of original theoretical, computational, and experimental contributions to the dynamics of gases, liquids, and complex fluids. See https://aip.scitation.org/journal/phf.

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JOURNAL

Physics of Fluids

DOI

10.1063/5.0138342 

ARTICLE TITLE

Modeling geysers triggered by an air pocket migrating with running water in a pipeline

ARTICLE PUBLICATION DATE

11-Apr-2023

 U$A FOR PROFIT HEALTHCARE

Audio-only telehealth remains common at safety net clinics

Trend raises questions about quality of care and equity for low-income patients

Peer-Reviewed Publication

RAND CORPORATION

More than two years into the COVID-19 pandemic, audio-only telehealth visits for both primary care and mental health services remained common at safety net clinics in California,  according to a new RAND Corporation study.

 

Although audio-only visits have declined since their peak early in the pandemic, the study published in the Journal of the American Medical Association found that in August 2022 audio-only visits still accounted for 1 in 5 primary care visits and 2 in 5 behavioral health visits among people who received care at Federally Qualified Health Centers in California.

 

Researchers say the higher rates of audio-only telehealth in safety net settings raises questions about the quality of care and equity for low-income patients, since the effectiveness  of audio-only telehealth has not been established.

 

“It is likely that these safety net clinics continued to deliver audio-only visits in high volume because of their role in improving access to health services,” said Lori Uscher-Pines, lead author of the study and a senior policy researcher at RAND, a nonprofit research organization.  “Our study raises important questions about what kind of role we want audio-only visits playing in the care of disadvantaged populations and the public in general going forward.”

 

The onset of the COVID-19 pandemic prompted many payers to begin reimbursing safety net clinics for telehealth services provided through video or audio-only technology. Previously, the clinics rarely received payment for telehealth services delivered directly to patients.

 

RAND researchers examined the experiences of 30 multisite Federally Qualified Health Centers in California that provide care for 1.3 million lower-income people. Many of the clinics are located in rural areas of the state. The study included information about billable in-person and telehealth (video and audio-only) visits from February 2019 to August 2022.

 

The study found that that number of primary care visits increased by 8.5% from February 2020 to August 2022, while the number of total behavioral visits increased 23% during the same period. The increases are likely the result of being able to widely offer telehealth services, even as the clinics lost staff members.

 

Researchers found that audio-only telehealth visits for primary care services peaked in April 2020, while audio-only visits for behavioral health peaked in March 2021.

 

Within primary care, the decline in audio-only visits from the early pandemic peak appears to coincide with the return of in-person visits rather than growth in video visits.

 

For primary care, the proportion of in-person visits increased from 30% in April 2020 to 71% by August of 2022.  Over the same period, audio-only visits decreased from 67% to 21%, while video visits increased from 4% to 7%.

 

For behavioral health, the proportion of in-person visits increased from 20% in April 2020 to 37% in August 2022. During that period, audio-only visits for behavioral health care decreased from 74% to 39%, while video visits increased from 8% to 23%.  

 

Researchers say that Federally Qualified Health Centers’ continued use of audio-only telehealth may be a result of the clinics and their patients not having access to the technology needed for video telehealth. In addition, since California’s Medicaid program (Medi-Cal) granted permanent payment parity for audio-only visits, there are no financial incentives for the clinics to limit audio-only visits.

 

“It appears likely that audio only visits in these settings will remain widespread in coming years,” Uscher-Price said. “More research is needed on the effectiveness of audio-only visits to inform their use in safety net settings.”

 

Funding for the research was provided by the California Health Care Foundation.

 

Other authors of the study are Colleen M. McCullough, Jessica L. Sousa Sarita D. Lee, Allison J. Ober, Kandice A. Kapinos, all of RAND; and Diana Camacho of the California Health Care Foundation.

 

RAND Health Care promotes healthier societies by improving health care systems in the United States and other countries.

 

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JOURNAL

Journal of the American Medical Association

METHOD OF RESEARCH

Data/statistical analysis

SUBJECT OF RESEARCH

People

ARTICLE TITLE

Changes in In-Person, Audio-Only, and Video Visits in California’s Federally Qualified Health Centers, 2019-2022

ARTICLE PUBLICATION DATE

11-Apr-2023