Friday, August 09, 2024

 

Repetition boosts belief in climate-skeptical claims, even among climate science endorsers


A single repetition increased the claims’ perceived truth for the strongest climate science supporters surveyed



PLOS

Repetition increases belief in climate-skeptical claims, even for climate science endorsers 

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Estimated mean truth ratings across repetition (repeated, non-repeated) and claim type (science-aligning, skeptic-aligning) in Experiment 1. Note. Error bars show 95% CI.

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Credit: Jiang et al. 2024, PLOS ONE, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)




Climate science supporters rated climate-skeptical statements as “truer” after just a single repetition, according to a study published August 7, 2024 in the open-access journal PLOS ONE led by Mary Jiang from The Australian National University, Australia, and coauthored by Norbert Schwarz from the University of Southern California, USA, and colleagues. The results held true even for the strongest climate science supporters surveyed.

Amidst the influx of content that a person consumes each day, the principle of motivated cognition suggests they are likelier to find truth in the statements that mirror their own beliefs. However, a second phenomenon, the illusory truth effect, suggests that just one repeated exposure to an idea — regardless of what it is — can elevate its perceived validity.

Schwarz and colleagues examined these ideas in the arena of climate science, questioning how self-identified climate science supporters might react when repeatedly exposed to climate-skeptical claims. Would repetition have an effect despite the conviction of their own beliefs?

The researchers fashioned two similar experiments, the first including 52 participants and the second 120. At least 90% of participants across both experiments endorsed climate science: the scientific evidence of human-caused climate change. 

Participants reviewed a series of statements classified as climate-skeptical, climate-science, or weather-related filler statements. After 15 minutes, they reviewed a second series of claims, half of which were repetitions of the previous statements. They rated the claims from “Definitely True” to “Definitely False” on a six-point Likert scale. In Experiment 2, the participants also classified each claim as scientist- or skeptic-aligned, and defined their own climate views using the Six Americas Super Short Survey.

In the climate science endorsers, the repetition did increase perceived validity of all claim types — including the ones participants flagged retrospectively as antithetical to their own beliefs. This held true even for the strongest climate science supporters, those participants who self-identified as “Alarmed” by climate change.

These results reinforce the benefits of amplifying truth by repetition and the risks of spreading false information, the researchers write. They suggest that further studies include non-climate issues (e.g., immigration, education, healthcare, etc.), experiment with time spans and rounds of repetition, and invert the experiment to study how climate skeptics are affected by repetition of claims supporting climate science.

Lead author Mary Jiang adds: “People find claims of climate skeptics more credible when they have been repeated just once. Surprisingly, this increase in belief as a result of repetition occurs even when people identify as a strong endorser of climate science.”

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In your coverage please use this URL to provide access to the freely available article in PLOS ONEhttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0307294

Citation: Jiang Y, Schwarz N, Reynolds KJ, Newman EJ (2024) Repetition increases belief in climate-skeptical claims, even for climate science endorsers. PLoS ONE 19(8): e0307294. https://doi.org/10.1371/journal.pone.0307294

Author Countries: Australia, USA

Funding: The author(s) received no specific funding for this work.

‘Fuel to the fire’: repeated climate-sceptic claims enough to nudge even the strongest of climate change endorsers



Australian National University





The threat of misinformation runs rampant in our digital age, where a single repetition of a climate-sceptical claim seems more true even to the staunchest of climate change endorsers, according to a new study from The Australian National University (ANU).

The researchers investigated whether repeated exposure to a climate-sceptic claim from a single source increases the perceived truth of that claim even when the claim runs counter to the receiver’s own climate change beliefs.

ANU PhD student and study lead author, Mary Jiang, said although study participants were more inclined to believe climate scientist-aligned claims over climate sceptic or climate denial claims, the power of repetition carries dangerous weight.

“More than 90 per cent of the study participants endorse climate science. While participants perceived claims aligned with climate scientists to be more truthful than claims aligned with climate scepticism, both types of claims seemed truer when repeated,” she said.

“This increase in perceived truth after repetition occurred even for groups highly concerned about climate change, and when people could later identify that the claim supports the other side.”

According to Ms Jiang, climate-sceptic claims may be presented alongside scientific facts in the name of ‘balanced’ reporting.

“Giving equal exposure to opposing voices makes it sound like the evidence and number of people in favour of each view is also equal. But most, if not all, climate scientists agree on human-induced climate change,” Ms Jiang said.

“While balanced reporting ensures fairness, it does not always paint an accurate or helpful picture and can add fuel to the fire.”

With recent figures suggesting that 89 per cent of people worldwide want more political action on climate change, the researchers warn of the insidious effect of repetition in making climate-sceptic arguments more credible, which in turn, puts everyone at risk of misinformation.

“When we used participants’ own classifications ensuring that they could later categorise a claim as sceptic-aligning, our climate science endorsing participants still considered repeated sceptic-aligning claims to be more truthful,” Ms Jiang said.

“Our study shows that repeat exposure to a claim from a single source is enough to nudge recipients towards acceptance of the repeated claim, even when their attitudes are aligned with climate science and that claim counteracts their beliefs.”

Study co-author, ANU Associate Professor Eryn Newman, said the findings shed light on our vulnerability to the simple repetition of claims.

“A feeling of familiarity is not a reliable cue to truth in digital environments where bots and other mechanisms can lead to a broad spread of false or misleading claims,” she said.

“When you look at the broader literature, being smarter or more critical in the analysis of information does not seem to protect people from shifts in belief because of repetition.

“This speaks to the important role of the ‘health’ of the information environment in which we engage.”

The researchers say it’s not all bad news.

“Study participants rated claims that were aligned with climate scientists as more true when they were repeated than when they were not, implying that it is beneficial to repeat claims that have scientific consensus, even when recipients are already in agreement with it,” Ms Jiang said.

Further research is needed to understand whether repeating counter-attitudinal information has similar effects on other samples, such as climate sceptics, who were underrepresented in the study. The researchers also want to find out whether repeating misleading claims can influence people who hold divided beliefs and attitudes on issues such as immigration, education and healthcare.

“The bottom line is, we should be cautious about repeating false information. Instead, repeat what is true and enhance its familiarity,” Associate Professor Newman said.

The research team also includes experts from the University of Southern California and the University of Melbourne.

The study is published in PLOS.

CASTEISM

Indian business owners from the stigmatized Dalit group experience a business income gap of around 16% compared to others



PLOS
It’s not who you know, but who you are: Explaining income gaps of stigmatized-caste business owners in India 

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Indian business owners from the stigmatized Dalit group experience a business income gap of around 16% compared to others.

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Credit: Raj et al., CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)



Indian business owners from the stigmatized Dalit group experience a business income gap of around 16% compared to others

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Article URL:  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0307660

Article Title: It’s not who you know, but who you are: Explaining income gaps of stigmatized-caste business owners in India

Author Countries: India, UK, Australia

Funding: The author(s) received no specific funding for this work.

 

TikTok videos glamorizing disordered eating behavior and extremely thin body image ideals make women feel worse about their bodies



TikToks—even neutral ones—harm women’s body image, but diet videos had the worst effect



PLOS

#ForYou? the impact of pro-ana TikTok content on body image dissatisfaction and internalisation of societal beauty standards 

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Less than 10 minutes of consuming TikTok content can have an immediate impact on young women’s body image satisfaction and internalization of the thin ideal.

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Credit: cottonbro studio, Pexels, CC0 (https://creativecommons.org/publicdomain/zero/1.0/)





Women who spend a lot of time on TikTok — especially those seeing a lot of pro-anorexia content — feel worse about their appearance, a new study shows. The results suggest that high TikTok exposure could harm mental health, reducing body image satisfaction and increasing the risk for disordered eating behavior. Madison Blackburn and Rachel Hogg from Charles Sturt University in Australia present these findings in the open-access journal PLOS ONE on August 7, 2024.

Since its launch, the short-form video app TikTok has had more than 2 billion downloads. The app’s algorithm curates content on a “For You” page based on a user’s interactions with previous videos, and content which glamorizes disordered eating behavior and extremely thin body image ideals can therefore quickly fill a users’ feed. To understand how TikTok content might affect women’s body image, Blackburn and Hogg surveyed 273 women between 18-28. They asked how much they used TikTok, and screened them for symptoms of disordered eating, body image, their attitudes toward beauty standards, and risk for orthorexia—a set of restricted diet and eating patterns focused on ridding oneself of “impure” or “unhealthy” foods or behaviors. The scientists then had half the participants watch a 7-8 minute compilation of disordered eating content from TikTok—including young women starving themselves or providing weight loss tips alongside juice cleanse and workout videos—while the other half of participants viewed neutral content with nature, cooking and animal themes.

Both groups reported a decrease in body image satisfaction after watching the videos, but those exposed to pro-anorexia content had the biggest decrease, and showed an increase in internalization of beauty standards. Women who used TikTok more than 2 hours per day reported more disordered eating behaviors, but the findings were not significant. While the study did not address how exposure to pro-anorexia content might affect people over time, the results suggest that weight-loss focused TikTok content might negatively affect viewers’ body image and beauty standards. The researchers recommend that there be better control over pro-anorexia content on TikTok. 

The authors add: “Our study showed that less than 10 minutes of exposure to implicit and explicit pro-anorexia TikTok content had immediate negative consequences for body image states and internalization of appearance ideals, suggesting psychological harm can occur for young female TikTok users even when explicit pro-anorexia content is not sought out and when TikTok use is of a short duration.”

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In your coverage please use this URL to provide access to the freely available article in PLOS ONEhttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0307597

Citation: Blackburn MR, Hogg RC (2024) #ForYou? the impact of pro-ana TikTok content on body image dissatisfaction and internalisation of societal beauty standards. PLoS ONE 19(8): e0307597. https://doi.org/10.1371/journal.pone.0307597

Author Countries: Australia

Funding: We acknowledge the financial support provided by Charles Sturt University.

 

60% of birds who survive collision with a building go on to die during rehabilitation care, and when these numbers are combined with instant deaths, US bird collision deaths might exceed 1 billion per year



PLOS
Rehabilitation outcomes of bird-building collision victims in the Northeastern United States 

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Ruby-crowned Kinglet.

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Credit: Kaitlyn Parkins, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)




60% of birds who survive collision with a building go on to die during rehabilitation care, and when these numbers are combined with instant deaths, US bird collision deaths might exceed 1 billion per year

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Article URL:  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0306362

Article Title: Rehabilitation outcomes of bird-building collision victims in the Northeastern United States

Author Countries: USA

Funding: The author(s) received no specific funding for this work.

 

Do smells prime our gut to fight off infection?


Nematodes react to the odor of pathogens by prepping their guts to withstand an infection. Do humans react similarly?



University of California - Berkeley

Mitochondrial response to pathogenic odors 

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Intestinal mitochondria in C. elegans are stained red. At left, a wild-type nematode exhibits a normal abundance of mitochondria. In the nematode at right, with its pathogen-associated circuit activated, the mitochondria are depleted. A new UC Berkeley study links activation of smell neurons by pathogen odors to mitochondrial depletion, called mitophagy.

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Credit: Julian Dishart and Andrew Dillin, UC Berkeley



Many organisms react to the smell of deadly pathogens by reflexively avoiding them. But a recent study from the University of California, Berkeley, shows that the nematode C. elegans also reacts to the odor of pathogenic bacteria by preparing its intestinal cells to withstand a potential onslaught.

As with humans, nematodes’ guts are a common target of disease-causing bacteria. The nematode reacts by destroying iron-containing organelles called mitochondria, which produce a cell's energy, to protect this critical element from iron-stealing bacteria. Iron is a key catalyst in many enzymatic reactions in cells — in particular, the generation of the body's energy currency, ATP (adenosine triphophate).

The presence in C. elegans of this protective response to odors produced by microbes suggests that the intestinal cells of other organisms, including mammals, may also retain the ability to respond protectively to the smell of pathogens, said the study's senior author, Andrew Dillin, UC Berkeley professor of molecular and cell biology and a Howard Hughes Medical Institute (HHMI) investigator.

"Is there actually a smell coming off of pathogens that we can pick up on and help us fight off an infection?" he said. "We've been trying to show this in mice. If we can actually figure out that humans smell a pathogen and subsequently protect themselves, you can envision down the road something like a pathogen-protecting perfume."

So far, however, there's only evidence of this response in C. elegans. Nevertheless, the new finding is a surprise, considering that the nematode is one of the most thoroughly studied organisms in the laboratory. Biologists have counted and tracked every cell in the organism from embryo to death.

"The novelty is that C. elegans is getting ready for a pathogen before it even meets the pathogen," said Julian Dishart, who recently received his UC Berkeley Ph.D. and is the first author of the study. "There's also evidence that there's probably a lot more going on in addition to this mitochondrial response, that there might be more of a generalized immune response just by smelling bacterial odors. Because olfaction is conserved in animals, in terms of regulating physiology and metabolism, I think it's totally possible that smell is doing something similar in mammals as it's doing in C. elegans."

The work was published June 21 in the journal Science Advances.


Stained mitochrondria in C. elegans

Mitochondria communicate with one another

Dillin is a pioneer in studying how stress in the nervous system triggers protective responses in cells — in particular, the activation of a suite of genes that stabilize proteins made in the endoplasmic reticulum. This activation, the so-called unfolded protein response (UPR), is "like a first aid kit for the mitochondria," he said.

Mitochondria are not only the powerhouses of the cell, burning nutrients for energy, but also play a key role in signaling, cell death and growth.

Dillin has shown that errors in the UPR network can lead to disease and aging, and that mitochondrial stress in one cell is communicated to the mitochondria of cells throughout the body.

One key piece of the puzzle was missing, however. If the nervous system can communicate stress through a network of neurons to the cells doing the day-to-day work of protein building and metabolism, what in the environment triggers the nervous system?

"Our nervous system evolved to pick up on cues from the environment and create homeostasis for the entire organism," Dillin said. "Julian actually figured out that smell neurons are picking up environmental cues and which types of odorants from the pathogens turn on this response."

Previous work in Dillin's lab showed the importance of smell in mammalian metabolism. When mice are deprived of smell, he found, they gained less weight while eating the same amount of food as normal mice. Dillin and Dishart suspect that the smell of food may trigger a protective response, like the response to pathogens, in order to prepare the gut for the damaging effects of ingesting foreign substances and converting that food to fuel.

"Surviving infections was the most important thing we did evolutionarily," Dillin said. "And the most risky and taxing thing we do every single day is eat, because pathogens are going to be in our food."

"When you eat food, it's also incredibly stressful, because the body is metabolizing the food but also generating ATP in the mitochondria from the nutrients that they're incorporating. And that generation of ATP causes a by-product called reactive oxygen species, which is very damaging to cells," Dishart said. "Cells have to deal with this increased existence of reactive oxygen species. So perhaps smelling food can prepare us to deal with that enhanced reactive oxygen species load."

Dillin speculates further that mitochondria's sensitivity to the smell of pathogenic bacteria may be a holdover from an era when mitochondria were free-living bacteria, before they were incorporated into other cells as power plants to become eukaryotes some 2 billion years ago. Eukaryotes eventually evolved into multicellular organisms with differentiated organs — so-called metazoans, like animals and humans.

"There's a lot of evidence that bacteria sense their environment in some way, though it's not always clear how they do it. These mitochondria have retained one aspect of that after being subsumed into metazoans," he said.

In his experiments with C. elegans, Dishart found that the smell of pathogens triggers an inhibitory response, which unleashes a signal to the rest of the body. This became clear when he ablated olfactory neurons in the worm and found that all peripheral cells, but primarily intestinal cells, showed the stress response typical of mitochondria that are being threatened. This study and others also showed that serotonin is a key neurotransmitter communicating this information throughout the body.

Dillin and his lab colleagues are tracking the neural circuits that lead from smell neurons to peripheral cells and the neurotransmitters involved along the way. And he's looking for a similar response in mice.

"I always hate it when I get sick. I'm like, ‘Body, why didn't you prepare for this better?’ It seems really stupid that you turn on response mechanisms only once you're infected," Dillin said. "If there are earlier detection mechanisms to increase our chances of survival, I think that's a huge evolutionary win. And if we could harness that biomedically, that would be pretty wild."

Other UC Berkeley authors of the paper are Corinne Pender, Koning Shen, Hanlin Zhang, Megan Ly and Madison Webb. The work is supported by HHMI and the National Institutes of Health (R01ES021667, F32AG065381, K99AG071935).

 

New guidelines to address racism in bioethics



Columbia University Irving Medical Center
Sandra Soo-Jin Lee 

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Sandra Soo-Jin Lee, PhD, is professor of medical humanities at Columbia University and President of the Association of Bioethics Program Directors.

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Credit: Columbia University Irving Medical Center




New York, NY — August 7, 2024 — Columbia University’s Division of Ethics Chief Sandra Soo-Jin Lee, PhD, is lead author of a new target article in The American Journal of Bioethics, titled "Racial Equity, Diversity and Inclusion in Bioethics: Recommendations from the Association of Bioethics Program Directors Presidential Task Force." This pivotal work responds to urgent calls for addressing racism within bioethics, highlighting the field's historical neglect in centering racial justice.

As President of the Association of Bioethics Program Directors (APBD), Dr. Lee led the APBD Presidential Task Force on Racial Equity, Diversity and Inclusion (REDI), which collaborated on the landmark article.The REDI Task Force represents ABPD Directors and bioethics scholars from a range of disciplines and fields and career stages, across twelve institutions in North America.

The article, based on the work of the REDI Task Force over two years, emphasizes the need for anti-racist practices within academic bioethics programs. It outlines specific recommendations to advance racial equity, diversity, and inclusion, urging bioethics organizations to integrate these principles into their scholarship, pedagogy, advocacy, and practice.

Dr. Lee stated: "This article is a crucial step toward rectifying the historical neglect of racial justice in bioethics. It provides actionable recommendations to foster a more inclusive and equitable field."

Key Recommendations:

●  Encourage research that reflects diverse values and worldviews, focusing on REDI.

●  Develop sustainable funding sources that support REDI scholarship and the development of underrepresented scholars.

●  Embed REDI into the canon of bioethics education programs and education across various health fields.

●  Develop mentorship and leadership succession plans that center REDI scholars and values.

●  Establish a more equitable distribution of REDI service work among faculty and more equal valuation of faculty salaries.

●  Embed REDI into how bioethicists provide policy, advisory, and consulting services.

●  Build equitable partnerships with marginalized communities historically impacted by racism.

●  Ensure policies and plans reflect REDI goals that encourage accountability and discrete timelines.

●  Develop tools to assess and measure the progress of REDI goals.

The full article is published open access and available to read for free online in The American Journal of Bioethics. To read the full article, visit this link.

For more information or to schedule an interview with Prof. Sandra Soo-Jin Lee, please contact David Lamb at dl3580@cumc.columbia.edu.

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About the Columbia University Division of Ethics 

Columbia University’s Division of Ethics is a multidisciplinary unit that focuses on conceptual, empirical, and policy-related bioethics research that addresses emerging challenges in biomedical research and health care. Research topics include gene sequencing and genetic testing, machine learning and medical decision-making, big data and the learning health system, and access to and equity of care. For more information about the Division of Ethics at Columbia University, please visit the Division website.

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National Academies progress report: Health disparities


Reducing diversity gaps in clinical trials is a societal imperative, according to UC Irvine professor


University of California - Irvine





Irvine, Calif., Aug. 7, 2024 — From costing society an estimated $11 trillion to hindering new discoveries in medicine and preventing access to effective interventions, underrepresentation of women, older adults and minorities in clinical research has several significant consequences, according to recent analyses commissioned by the National Academies of Sciences, Engineering and Medicine.

 

Jonathan Watanabe, UC Irvine professor of clinical pharmacy practice and director of the campus’s Center for Data-Driven Drugs Research and Policy, recently provided expert commentary on the issue published online in Journal of the American Geriatrics Society.

He provides recommendations and cites progress achieved based on NASEM activities between 2020 and 2022 that examined and identified the challenges and opportunities involved in overcoming barriers to increased research participation by diverse populations.

 

Women are more likely to experience dementia, and older adults are particularly affected by chronic conditions like diabetes, heart disease and hypertension, requiring multiple medications, yet they’re marginalized in clinical trials. Addressing this is crucial for advancing health equity and elevating the quality of care for these excluded groups.

 

“The goal of my paper is to empower efforts on multiple levels to enhance the representation of women, minorities and older adults to improve their health outcomes. It serves as a valuable resource of actionable suggestions and reports on the progress that’s been made through coordinated national policy efforts and collaboration from various stakeholders, including research institutions, funding bodies and medical journals,” Watanabe says.

 

Importantly, numerous mandated policies have now been issued to boost representation, and federal regulations now require trial sponsors to submit diversity action plans when presenting study protocols. Enrollment goals and their rationale, as well as strategies for achieving them, must be included, along with details on age group, sex, racial and ethnic characteristics, disease prevalence among different demographics, specific outreach and enrollment methods, inclusion criteria, and diversity training for study personnel.

 

Enhancing the diversity of the workforce is also critical for health equity. It has repeatedly been shown that inclusivity in this group improves the ability to understand sectors of the population that are still regularly absent from clinical research on conditions that affect them and leads to increased representation in clinical studies.

 

“Addressing study participant and workforce inclusion gaps is both achievable and necessary. It requires intentional and committed efforts now coordinated by a broad range of stakeholders,” Watanabe says. “Fortunately, thanks to NASEM and the resulting federal efforts, we have taken a crucial step forward in improving the quality and applicability of clinical studies and now have informed guidance that can be applied to ensuring equitable representation and improving health outcomes for all.”

 

About the University of California, Irvine: Founded in 1965, UC Irvine is a member of the prestigious Association of American Universities and is ranked among the nation’s top 10 public universities by U.S. News & World Report. The campus has produced five Nobel laureates and is known for its academic achievement, premier research, innovation and anteater mascot. Led by Chancellor Howard Gillman, UC Irvine has more than 36,000 students and offers 224 degree programs. It’s located in one of the world’s safest and most economically vibrant communities and is Orange County’s second-largest employer, contributing $7 billion annually to the local economy and $8 billion statewide. For more on UC Irvine, visit www.uci.edu.

 

Media access: Radio programs/stations may, for a fee, use an on-campus studio with a Comrex IP audio codec to interview UC Irvine faculty and experts, subject to availability and university approval. For more UC Irvine news, visit news.uci.edu. Additional resources for journalists may be found at https://news.uci.edu/media-resources.