US Female physicians at elevated risk for suicide
Many physicians struggle with depression and burnout; the consequences, can be tragic
University of California - San Diego
In a new analysis of data from the Centers for Disease Control and Prevention, researchers at University of California San Diego School of Medicine found that female physicians in the U.S. had a 53% higher suicide risk compared to females in the general population. Physicians were also more likely to experience various risk factors for suicide, such as mental health struggles or legal issues. The findings, published in JAMA Psychiatry, underpin the need for more comprehensive suicide prevention strategies in a population that experiences unique and significant workplace stressors.
“We're seeing slow but steady progress in promoting wellness in the medical profession, but there’s clearly still a long way to go,” said senior study author Sidney Zisook, M.D., a professor of psychiatry at UC San Diego School of Medicine and a psychiatrist at UC San Diego Health. “Many suicides could be prevented if we destigmatize mental health treatment and make it more accessible and feasible for physicians.”
For physicians, mental health struggles like burnout and depression are all-too-common due to the high-stress nature of their profession. Physicians are regularly required to work long hours within complex health systems and are also responsible for making life-or-death decisions. While older research has suggested that physicians may be at higher risk for suicide than the general population, more recent studies have been inconclusive. Recent research is also ambiguous about the role of gender in suicide risk among physicians.
“Our study helps confirm the fact that physicians are at high risk for suicide, and it tells us that we need to be even more vigilant about this when it comes to female physicians,” said first author Hirsh Makhija, M.S., a postgraduate volunteerresearcher in the Department of Psychiatry at UC San Diego School of Medicine. “Existing suicide prevention programs may not be enough.”
The new study, which analyzed data from the National Violent Death Reporting System from 2017 to 2021, helps fill this gap in knowledge. By investigating more than 137,000 suicides across the U.S., the researchers found:
- While males accounted for 80% of physicians who died by suicide, female physicians had a 53% higher rate of suicide compared to females in the general population.
- Compared to the general population, physicians of either sex who died by suicide were 35% more likely to experience depressed mood, 66% more likely to experience other mental health issues, more than twice as likely to experience job problems, and 40% more likely to experience legal problems.
- Physicians were 85% more likely to use poisoning for suicide, and more than four times as likely to use sharp instruments.
- Physicians were 75% more likely to test positive for benzodiazepines, 32% more likely to test positive for opiates or opioids, 53% more likely to test positive for cardiovascular agents, and almost three times as likely to test positive for drugs not prescribed for home use.
While the study did not seek to determine why female physicians are at higher risk of suicide, the researchers hypothesize that it is due to factors such as under-recognition for their work, inequitable pay and opportunities for promotion, sexual harassment on the job, and often greater domestic responsibilities leading to work-life imbalance.
The findings highlight the need for comprehensive and multimodal strategies for enhancing suicide prevention. Specifically, the study authors recommend limiting access to lethal means, such as medications and sharp instruments and improving mental health resources and support for physicians. They also emphasize the need to continue investigating the root causes of mental health struggles in the health care field as a whole in order to develop new and better approaches to suicide prevention.
“Our work underpins the need for continued efforts to destigmatize mental health care and shift the culture of medicine from one of self-reliance and silent suffering to one of sharing, caring, and connecting,” added Zisook, “Self-care and self-compassion should be part of what it means to be a consummate medical professional.”
Link to full study.
Additional coauthors of the study include Judy E. Davidson at UC San Diego School of Medicine, Kelly C. Lee at UC San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, Arianna Barnes at Barnes Jewish Hospital and Amanda Choflet at Northeastern University.
The study received no external funding.
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Journal
JAMA Psychiatry
COI Statement
Kelly Lee reported honoraria for speaking on adult attention-deficit/hyperactivity disorder from WebMD Health Corp and consulting for Biogen outside the submitted work. Sidney Zisook reported grants from Compass Pathways outside the submitted work. No other disclosures were reported.
US National incidence of physician suicide and associated features
JAMA Psychiatry
About The Study: The findings of this study show a higher incidence of suicide for U.S. female physicians compared to female non-physicians. Comprehensive and multimodal suicide prevention strategies remain warranted.
Corresponding Author: To contact the corresponding author, Hirsh Makhija, MS, email himakhij@ucsd.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(10.1001/jamapsychiatry.2024.4816)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Journal
JAMA Psychiatry
Which veterans have the highest risk of dying by suicide? New study sheds light
Data from the first year of VA-wide Comprehensive Suicide Risk Evaluations for veterans show firearm access, suicidal thinking and suicide planning were major predictors of suicide death
Michigan Medicine - University of Michigan
In the ongoing effort to reduce the number of veterans who die by suicide, a new study identifies key factors that predict whether veterans who received a Comprehensive Suicide Risk Evaluation, the standardized suicide risk assessment implemented nationally in the Veterans Health Administration, will go on to die by their own hands.
The findings could help Veterans Affairs clinicians and others work to prevent more suicide deaths among veterans in this high-risk category.
The study focused on veterans who received a CSRE assessment from a VA clinician. The CSRE program launched nationally six years ago, and the new study looks at suicide deaths among veterans who received an assessment during its first year.
Even after going through the CSRE process, the new study finds that veterans who were actively experiencing suicidal thoughts, had made suicide plans, had access to firearms, or had a history of mental health inpatient stays were most likely to die by suicide, compared with others who had been through a CSRE but didn’t have these risk factors.
The study looked at suicide deaths both in the first 30 days and the first year after a CSRE.
In all, there were 791 suicides following the 269,374 CSREs that were completed for 153,736 Veterans Health Administration patients between November 2019 and December 2020, the study finds. Of those, 144 suicides occurred within 30 days after a CSRE; the rest were within a year of the CSRE visit.
While most of those who died by suicide after a CSRE had been classed as having an especially high risk of near-term or long-term suicide based on their answers on the CSRE scale, there were also suicide deaths among those who fell into the lower-risk category on their CSRE.
The study, published in JAMA Network Open by a team from the University of Michigan Medical School’s Department of Psychiatry, the VA Center for Clinical Management Research, and the VA Ann Arbor Healthcare System, was led by Kevin Saulnier, Ph.D., a psychologist who has performed CSREs as part of his practice at VA Ann Arbor’s mental health clinic.
“Suicide prediction has long been a challenge for the field, so this finding that some of the risk factors that are routinely assessed in the Veterans Health Administration predicted future risk of suicide is important,” says Saulnier. “While this study did not look at what treatments and supports patients received after their CSRE, it can immediately inform clinicians as they use their judgement to work with patients.”
Saulnier and colleagues also recently published another paper in JAMA Network Open showing that suicide mortality was lower among veterans newly diagnosed with post-traumatic stress disorder who received the evidence-based treatment know as cognitive processing therapy or prolonged exposure (CPT/PE).
More about CSREs
CSRE sessions, which can take about a half hour, are designed to evaluate a veteran’s current risk factors and protective factors for suicide using a standardized checklist.
Part of the appointment can be the development of a safety plan that maps out who the veteran can turn to when they feel suicidal, including the Veterans Crisis Line that can be reached by phone at 988, by text at 838255 and by online chat at https://www.veteranscrisisline.net/.
Depending on the clinician’s judgment and the patient’s preferences, a CSRE can also lead to referrals to specific mental health care, the provision of free gun locks for any firearms the veteran possesses, and other steps.
In some states, including Michigan, “red flag” laws allow clinicians, family members and law enforcement to seek a court order to remove firearms from the home of a person they believe to be a danger to themselves or others. The U-M Institute for Firearm Injury Prevention offers a free toolkit to help individuals understand this option, called an Extreme Risk Protection Order.
Using research to improve care
The new study could help clinicians prioritize firearm-related steps for CSRE patients, as well as escalating patients with current suicide-related thoughts or plans to higher levels of care including inpatient psychiatric care if needed.
Saulnier notes that predictive models for suicide have already become part of VA care management decisions, and that the new findings could help refine those models. He and colleagues are also planning to study what treatments veterans received after having a CSRE, and also non-fatal suicide attempts.
The study only includes veterans receiving care from the VA, where brief screening for suicide risk is universal. CSREs have become standard care for those whose initial screen shows that they have been having suicidal thoughts or thinking about how they might attempt suicide.
Veterans cared for in non-VA settings may not get screened for suicide risk unless they’re seeking care for a behavioral health issue, though more hospitals and health systems are now implementing universal screening and follow-up evaluations for those who screen positive.
More about the study
In addition to the factors that predicted suicide deaths by 30 or 365 days after a CSRE, Saulnier and colleagues also found some factors were actually linked to a protective effect, or reduced risk.
More research on this is needed, he said – including research on those who completed CSREs and were considered very high risk for immediate or later suicide but did not die by suicide during the follow-up period.
The team also found that some factors that have been seen in other research as protective against suicide risk were not associated with lower risk of suicide death, such as connection to others or a sense of hope. This may be due to the very high risk of suicide that veterans who receive CSREs already face.
In an accompanying commentary, Rebecca Rossom, M.D., M.S. of the HealthPartners Institute wrote, “As the largest integrated health system in the US, true universal suicide risk screening followed by safety planning in the Veterans Health Administration could provide powerful evidence regarding the effectiveness of these approaches to suicide prevention. These findings are critical as the US continues to grapple with the public health epidemic of suicide.”
More information about veteran suicide risk, prevention, options for reducing access to lethal means such as firearms, and crisis support is available at https://www.mentalhealth.va.gov/suicide_prevention/index.asp
If you or someone you know may be considering suicide, or having a mental health or addiction-related crisis, the 988 Lifeline is available for free to anyone, at all times, in both English and Spanish. Call 988 from any phone, text 988 from a mobile device, or visit https://988lifeline.org/ for live webchat, information on available help, and live help via videophone for people who are Deaf or hard of hearing. Or contact the Crisis Text Line by texting TALK to 741741.
In addition to Saulnier the study’s authors are Courtney L. Bagge, Ph.D.; Dara Ganoczy, M.P.H.; Nazanin H. Bahraini, Ph.D.; Jennifer Jagusch, M.S.W.; Avinash Hosanagar, M.D.; Mark A. Ilgen, Ph.D.; and Paul N. Pfeiffer, M.D. Saulnier, Bagge, Pfeiffer and Ilgen are members of the U-M Institute for Healthcare Policy and Innovation and the VA CCMR. Ilgen is also a member of the U-M Institute for Firearm Injury Prevention.
Suicide Risk Evaluations and Suicide in the Veterans Health Administration, JAMA Network Open, doi:10.1001/jamanetworkopen.2024.61559
Journal
JAMA Network Open
Method of Research
Data/statistical analysis
Subject of Research
People
Article Title
Suicide Risk Evaluations and Suicide in the Veterans Health Administration
Article Publication Date
25-Feb-2025