Only few disinfectants are capable of inactivating hepatitis A virus
Virology
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Only a few surface disinfectants sufficiently reduce the risk of infection from hepatitis A virus.
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Credit: © RUB, Marquard
Two effective agents
The researchers applied HAV particles to steel surfaces to determine the number of infectious virus particles over 60 days. “We detected infectious particles on the surface for up to 40 days, which indicates a high stability of the virus,” says doctoral student Lilli Pottkämper. It took around 18 days for the number of infectious particles to be reduced by half.
The research team then applied various disinfectants to the samples. Among the nine products tested were alcohol-based, aldehyde-based, one peracetic acid-based, one oxygen-based and one hydrogen peroxide-based. “With the exception of the two aldehyde-based products, none of the disinfectants reduced the risk of infection to a sufficient extent,” points out Lilli Pottkämper.
Preventing infection
The extent to which infection via contaminated surfaces contributes to hepatitis A infection rates is not known. The virus isexcreted via faeces and then ingested orally, often via contaminated food or drinking water. “As matters stand, effective surface disinfection could help to prevent infection, especially in the case of high infection rates,” concludes Lilli Pottkämper.
Journal
Journal of Hospital Infection
Method of Research
Experimental study
Subject of Research
Cells
Article Title
Stability and Inactivation of Hepatitis A Virus on Inanimate Surfaces
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