Bangladesh's waters reeking with drugs, chemicals

by Saleem Shaikh, SciDev.Net

Antibiotic residues can also make their way to farmlands. 

Credit: Balaram Mahalder (CC BY-SA 3.0)

High levels of antibiotic residues, other medicines and chemicals present in Bangladesh's ponds, canals, lakes, rivers and other surface waters are contributing to a spike in antibiotic resistance in the country, says a new study.

Antibiotic resistance results from microorganisms (such as bacteria, fungi, viruses and parasites) mutating when exposed to antimicrobial drugs that become ineffective in the prevention, treatment and spread of infectious diseases, according to the WHO.

Factors that make low- and middle-income countries like Bangladesh vulnerable to increased emergence and spread of anti-microbial resistance in the environment include poor regulation of antimicrobial drug use, high volume of antimicrobials used in human medicine and agricultural production and poor wastewater management, the study noted.

Published 10 April in Science of the Total Environment, the study found concentrations of ciprofloxacin and clarithromycin to be the highest. Other antibiotics found in the surface waters of rural and urban Bangladesh include amoxicillin,clindamycin, lincomycin, linezolid, metronidazole, moxifloxacin, nalidixic acid and sulfapyridine.
The study findings were based on an analytical technique (chromatography-mass spectrometric analysis) that measures the mass-to-charge ratio of ions. A total of 17 water samples were taken from ponds, canals, lakes, rivers, household hand pumps and sites near submersible pumps and wastewater treatment plants from April to May 2019.

"Because these waters are key sources of consumption for humans, animals and irrigation purposes, dumping of antibiotic residues has become a leading cause for enhanced multi-drug resistance in bacteria that cause diseases in humans, animals and agriculture crops," says Luisa Angeles, lead study author and research scholar at the State University of New York.

According to Angeles, antibiotic residues are continuously released into the natural aquatic environment from hospital wastewater outlet pipes and wastewater treatment plants.

Non-antibiotic drugs and other micro-pollutants are adding to antibiotic-resistance, the study found. For example, the anti-depressant fluoxetine has been found to promote bacterial mutation, which leads to multiple resistance of Escherichia coli to antibiotics such as fluoroquinolones, β–lactams, aminoglycosides, tetracycline, and chloramphenicol.

"The assessment led to the discovery that five agricultural fungicide compounds—namely hexaconazole, imidacloprid, propiconazol, tebuconazole and tricyclazole—were prominently present in the water samples, showing their largescale use to kill farm pests," Angeles tells SciDev.Net.

"Ubiquity of antifungal agents in urban and rural waters is of grave worry, as it may be contributing to the alarming rise of multi-drug resistant fungal diseases (such as Candida auris) recently seen in humans throughout the world," the study said.

Despite elevated risks and growing cases of antibiotic resistance in the country, there is a lack of information about the types, quantity and scale of antibiotics prevalence in surface waters that hampers action to mitigate the risks, says Hanan Balkhy, assistant director-general for antimicrobial resistance at WHO, Geneva.

"The study findings could significantly help plug the information gap and tap official action to address the risks," Balkhy tells SciDev.Net.

He suggests that Bangladesh build a system-wide health-care strategy to promote sane and responsible use of antibiotics in humans, farm animals and crops through evidence-based interventions and actions at the individual and national levels.

Antibiotic-resistance in Tanzania is an environmental problem

More information: Luisa F. Angeles et al. Retrospective suspect screening reveals previously ignored antibiotics, antifungal compounds, and metabolites in Bangladesh surface waters, Science of The Total Environment (2019). DOI: 10.1016/j.scitotenv.2019.136285

Journal information: Science of the Total Environment 

Provided by SciDev.Net

Hacker brings video to audio cassette tape

by Peter Grad , Tech Xplore

Credit: CC0 Public Domain

Admit it. Somewhere in your basement or attic are dust-covered boxes filled with your Dad's old cassette tape music collection (your Mom is likely tidier and disposed of hers years ago.) Although last year there was an uptick in sales for audio cassettes at levels not achieved since the early 2000s, the format generally has been considered a useless relic of a long-gone era.

But one YouTube hacker begs to disagree.

Perhaps taking advantage of newfound free time afforded by self-isolation that has been imposed worldwide due to COVID-19, hacker Kris Slyka thought to himself: How can I put old audio cassette tapes from the Eighties to better use today?

So he applied his knowledge of Python and Java and found a new use for those 4.25" x 2.75" plastic cases packing up to 300 feet of magnetic tape. He repurposed them to record video.

It was no small feat. And while the video quality is not exactly high-def—in fact, it's quite low-def— the accomplishment remains impressive.

Today's high resolution video formats contain 8.3 million pixels and display 240 frames per second. Working with a format—magnetic audio cassette tape—bearing far greater constraints, Slyka was limited to a display of merely 100x75 pixels, a total of 7,500 pixels, and a speed of 5 frames per second. No one will be watching "The Avengers" or "Black Panther" on this format any time soon.

As one headline referred to the invention: "Hacker Figures Out How to Capture Horrible-Quality Video on Audio Cassettes."

Jokes aside, the accomplishment shows that with drive, determination and ingenuity, a spirited developer can make inroads in technology that were considered near impossible in earlier times. And we don't yet know what improvements or practical uses may lie ahead.

In fact, at least one earlier commercial effort to utilize audio tapes for video was made in the 1980s with the Fisher-Price PXL 2000 PixelVision camcorder designed especially for children. The toy proved to be a loser as video quality was abominable, even for audiences of five-year-olds.

Slyka's project accomplished higher-quality results. He was able to double the frame rate by interlacing images. He also was able to make use of the two tracks assigned to audio on cassette tapes by using one of the tracks to encode color instructions. The Fisher-Price camcorder was limited to black-and-white recordings.

Audio cassettes enjoyed immense popularity in the Eighties, propelled largely by the introduction of the Sony Walkman. For the first time, folks could listen to their favorite music outside their homes; unlike transistor radios, the Walkman allowed them to choose their own songs. Cassette players also contributed to the aerobic craze of the Eighties as physical fitness buffs discovered that listening to personal music compilations through stereo earphones made strenuous workouts more pleasurable. By 1989, 83 million cassette tapes were sold.

Fittingly, Slyka used a Sony tape recorder for his project. Last summer marked the 40th anniversary of the release of the first Sony Walkman.

While Slyka's creation has room for improvement, it at least gives us some consolation that those old, dusty cassette tapes may yet have a second life. And if not, they make great door st

End of an era: Sony to stop making Betamax tapes

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More information: amplifoxed.bandcamp.com/album/side-a-one-day

Zoom security feature let unapproved users view meetings, researchers find

by Suhauna Hussainstaff Writer, Los Angeles Times

Credit: CC0 Public Domain

Zoom, the videoconferencing service that has exploded into the vacuum created by the COVID-19 outbreak, has endured the revelation of a string of privacy and security flaws in recent days. Now researchers have identified just such a flaw in a feature marketed specifically as a way to make meetings more secure.

Zoom said Wednesday it had fixed a vulnerability with its Waiting Room feature.

The feature allows meeting hosts to keep would-be participants in a digital queue pending approval. Medical professionals could use it to host multiple telehealth appointments in a row, and hiring managers could conduct stacked video interviews, the company suggested in a February blog post.

As users have encountered problems with "zoombombing"—whereby participants interrupt and derail meetings, often by using offensive imagery or racist slurs—the company has pointed to the waiting room feature as a way to protect from this type of intrusion.

But security researchers examining the desktop client for vulnerabilities found that Zoom servers would automatically send a live video data to users in the meeting's waiting room, even if they had not yet been approved to join by the person holding the meeting. These users were also sent the meeting's decryption key—the code needed to unlock secure communications. Users could hypothetically extract the video live stream, researchers said.

"If you were moderately technically sophisticated, you could watch what was going on while in the waiting room," said Bill Marczak, a fellow at the Citizen Lab and a postdoctoral researcher at UC Berkeley who found the vulnerability. An audio stream of the call, however, was not accessible.

Marczak said he and John Scott-Railton of the Citizen Lab notified Zoom last week. They detailed their findings in a report published Wednesday, after they receive an email from the company saying the issue had been fixed.

On Wednesday, Zoom Chief Executive Eric Yuan mentioned during a webinar held to address privacy concerns that Zoom had fixed an issue with its waiting room feature.

"We updated our server. Our waiting room vulnerability is already fixed," Yuan said on the webinar. "From a server side, we did not send audio and video data to the waiting room client. However, we did send the session key ... . We did not think that was safe, so we changed our server."

Yuan's comment did not align with what Marczak and Scott-Railton found, they wrote. The video stream was previously accessible, though the issue has since been fixed, Marczak said.

Zoom did not immediately respond to a request for comment about this discrepancy.

Zoom to focus on security, privacy, CEO says, as usage booms during coronavirus crisis

A model for better predicting the unpredictable byproducts of genetic modification

by North Carolina State University

Credit: CC0 Public Domain

Researchers are interested in genetically modifying trees for a variety of applications, from biofuels to paper production. They also want to steer clear of modifications with unintended consequences. These consequences can arise when intended modifications to one gene results in unexpected changes to other genes. A new model aims to predict these changes, helping to avoid unintended consequences, and hopefully paving the way for more efficient research in the fields of genetic modification and forestry.

The research at issue focuses on lignin, a complex material found in trees that helps to give trees their structure. It is, in effect, what makes wood feel like wood.

"Whether you want to use wood as a biofuel source or to create pulp and paper products, there is a desire to modify the chemical structure of lignin by manipulating lignin-specific genes, resulting in lignin that is easier to break down," says Cranos Williams, corresponding author of a paper on the work and an associate professor of electrical and computer engineering at NC State. "However, you don't want to make changes to a tree's genome that compromise its ability to grow or thrive."

The researchers focused on a tree called Populus trichocarpa, which is a widely used model organism—meaning that scientists who study genetics and tree biology spend a lot of time studying P. trichocarpa.

"Previous research generated models that predict how independent changes to the expression of lignin genes impacted lignin characteristics," says Megan Matthews, first author of the paper, a former Ph.D. student at NC State and a current postdoc at the University of Illinois. "These models, however, do not account for cross-regulatory influences between the genes. So, when we modify a targeted gene, the existing models do not accurately predict the changes we see in how non-targeted genes are being expressed. Not capturing these changes in expression of non-targeted genes hinders our ability to develop accurate gene-modification strategies, increasing the possibility of unintended outcomes in lignin and wood traits.

"To address this challenge, we developed a model that was able to predict the direct and indirect changes across all of the lignin genes, capturing the effects of multiple types of regulation. This allows us to predict how the expression of the non-targeted genes is impacted, as well as the expression of the targeted genes," Matthews says.

"Another of the key merits of this work, versus other models of gene regulation, is that previous models only looked at how the RNA is impacted when genes are modified," Matthews says. "Those models assume the proteins will be impacted in the same way, but that's not always the case. Our model is able to capture some of the changes to proteins that aren't seen in the RNA, or vice versa.

"This model could be incorporated into larger, multi-scale models, providing a computational tool for exploring new approaches to genetically modifying tree species to improve lignin traits for use in a variety of industry sectors."

In other words, by changing one gene, researchers can accidentally mess things up with other genes, creating trees that aren't what they want. The new model can help researchers figure out how to avoid that.

The paper, "Modeling cross-regulatory influences on monolignol transcripts and proteins under single and combinatorial gene knockdowns in Populus trichocarpa," is published in the journal PLOS Computational Biology

Wood formation model to fuel progress in bioenergy, paper, new applications

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Journal information: PLoS Computational Biology 

New paper points out flaw in Rubber Hand Illusion raising tough questions for psychology

by University of Sussex

A demonstration of the Rubber Hand Illusion. Credit: University of Sussex

A world-famous psychological experiment used to help explain the brain's understanding of the body, as well as scores of clinical disorders, has been dismissed as not fit-for-purpose in a new academic paper from the University of Sussex.

The Rubber Hand Illusion, where synchronous brush strokes on a participant's concealed hand and a visible fake hand can give the impression of illusory sensations of touch and of ownership of the fake hand, has been cited in more than 5,000 articles since it was first documented more than 20 years ago.

In a new research paper Dr. Peter Lush, Research Fellow at the Sackler Centre for Consciousness Science at the University of Sussex, demonstrates that the control conditions typically used in the Rubber Hand Illusion do not do they job they need to do.

His results show that the commonly reported effects of the Rubber Hand Illusion can be attributed to imaginative suggestion'—otherwise known as 'hypnosis'.

Dr. Lush is calling for the development of valid control methods for the Rubber Hand Illusion while raising the prospect that suggestion effects could confound many other effects throughout psychological science.

He said: "The Rubber Hand Illusion is a cornerstone of contemporary consciousness science. It has been extended to almost any body part imaginable and investigated in just about any clinical disorder you can imagine.

"This paper prompts the reinterpretation of all this work, and other work which uses the same control methods, such as the full body illusion, the out of body illusion and the enfacement illusion. Existing claims that the rubber hand illusion is not a suggestion effect are invalid, and therefore it is possible that existing reports of the rubber hand illusion are entirely attributable to suggestion effects."

Last year Dr. Lush and colleagues reported in a paper, currently under peer review but available as a preprint on PsyArxiv, substantial correlations between response to the Rubber Hand Illusion and response to imaginative suggestion , or phenomenological control, in a large sample of 353 participants. This study shows that response to the Rubber Hand Illusion is, partially or entirely a suggestion effect.

Psychologists have long been aware of the dangers of 'demand characteristics'—in which subjects, often without realising it, say what they implicitly think they ought to say.

Dr. Lush's work takes these concerns much further by showing that how suggestible someone is can dramatically influence what people report in the Rubber Hand Illusion—and potentially in many other experiments too.

Dr. Lush said: "The extent to which phenomenological control confounds psychological science is currently unknown, but may be substantial. If the effects are widespread—and they may well be—psychology will be faced with a new crisis of generalisability."

In the new study, published this week in Collabra: Psychology, an innovative design was employed to test imaginative suggestion in rubber hand illusion reports.

Participants were provided with information about the Rubber Hand Illusion procedure (including a text description and a minute-long video demonstration of the illusion) and then asked to fill out a standard questionnaire on what they would expect to happen if they were a participant in the procedure.

Strikingly, people expect the same pattern of results that is typically found in Rubber Hand Illusion studies, both for the 'experimental' conditions and the 'control' conditions.

According to Dr. Lush, this means the control methods that have been used for 22 years of Rubber Hand Iillusion studies, are not fit for purpose because demand characteristics have not been adequately controlled, meaning the illusion may be, partially or entirely, a suggestion effect.

He added: "Few contemporary scientists seem to be aware of the extent to which imaginative suggestion can drive experience, and so haven't been able to control for suggestion effects in the Rubber Hand Illusion.

"Future studies of the Rubber Hand Illusion—and many other similar effects—will need to take individual differences in suggestibility properly into account, if they are to make justifiable claims about how people experience their bodies."

Study shows expectation important component of rubber-hand illusion

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More information: Peter Lush, Demand Characteristics Confound the Rubber Hand Illusion, Collabra: Psychology (2020). DOI: 10.1525/collabra.325

The science of how diet can change the way sugar tastes

by University of Sydney

We know humans also experience changes in taste

 perception in response to diet. Credit: Pixabay

The food animals eat can change how they perceive future food. This response uses the same machinery that the brain uses to learn, new research has found.

Researchers at the University of Sydney have discovered the basic science of how sweet taste perception is fine-tuned in response to different diets. While it has long been known that food can taste different based on previous experience, until now we didn't know the molecular pathways that controlled this effect.

Professor Greg Neely at the Charles Perkins Centre and School of Life and Environmental Sciences with Professor Qiaoping Wang (formerly at the Charles Perkins Centre and now based at Sun Yat-Sen University, China) used fruit flies to study sweet taste. They learned that taste is highly subjective based on previous experience.

Professor Neely said they learned four important things:

1. The food animals eat can change how they perceive future food.
2. This response uses the same machinery that the brain uses to learn.
3. Pathways that can extend lifespan were also involved in enhancing taste perception, and diets in fruit flies that promote long life were also found to enhance taste perception.
4. Lifespan, learning and sensory perception are linked in ways we are just starting to understand.

Fruit fly 'tongue'

"We found that the fruit fly 'tongue' – taste sensors on its proboscis and front feet—can learn things using the same molecular pathways that the fly brain uses to learn things," Professor Neely said. "Central to this is the neurotransmitter dopamine."

"It turns out these are also the same chemical pathways that humans use to learn and remember all sorts of things," Professor Neely said. "This really highlights how learning is a whole-body phenomenon; and was a complete surprise to us."

Professor Wang, who led the study, said: "We were surprised to find that a protein-restricted diet that makes an animal live much longer also turns up the intensity of sucrose perception for that animal, and that is dependent on the same learning and longevity pathways.



"The response was also really specific. For example, when we fed flies food that had no sweetness, the animals' sweet taste perception was enhanced, but only for glucose, not for fructose. We have no idea why they specifically focus just on one kind of sugar when they perceive them both as sweet."

"We also found that eating high amounts of sugar suppressed sweet taste perception, making sugar seem less sweet," Professor Neely said. "This finding, which occurs through a different mechanism, matched nicely with recent results from our colleague Monica Dus at the University of Michigan, who is the world expert in this area."

Taste study

The researchers found if they changed the diet of the fruit fly (increasing sugar, removing taste of sugar, increasing protein, changing sugar for complex carbohydrate), this drastically altered how well the fruit fly could taste subsequent sugar after a few days.

"We found that when flies ate unsweetened food, this made sugary food taste much more intense," Professor Wang said.

"Then we looked at all the proteins that changed in the fruit fly 'tongue' in response to diet, and we investigated what was happening," Professor Neely said.

They found the sensation of taste is controlled by dopamine (the "reward" neuromodulator). The researchers then mapped the pathway and found the same pathways that are well established as controlling learning and memory or promoting long life also enhance taste sensation.

"While this work was conducted in fruit flies, the molecules involved are conserved through to humans. We know humans also experience changes in taste perception in response to diet, so it's possible the whole process is conserved; we will have to see," Professor Wang said.

The research published in Cell reports, is a follow up study to Professor's Neely's work testing the effects of artificial sweeteners. That research found artificial sweeteners activate a neuronal starvation pathway, and end up promoting increased food intake, especially when combined with a low-carb diet.

"Our first studies were focused on how different food additives impact the brain, and from this we found taste changed in response to diet, so here we followed up that observation and describe how that works," Professor Neely said. "Turns out the fly 'tongue' itself is remembering what has come before, which is kind of neat."

Fat fruit flies: High-sugar diet deadens sweet tooth; promotes overeating, obesity in flies

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More information: Qiao-Ping Wang et al. PGC1α Controls Sucrose Taste Sensitization in Drosophila, Cell Reports (2020). DOI: 10.1016/j.celrep.2020.03.044

Journal information: Cell Reports 

Video games improve the visual attention of expert players

by Frontiers

Credit: CC0 Public Domain

Action real-time strategy video games such as World of Warcraft, Age of Empires, and Total War are played by millions. These games, which can be won through strategic planning, selective attention, sensorimotor skills, and teamwork place considerable demands on the brain.

Research has shown that experience of playing games can improve cognitive development such as greater sensitivity to contrasts, better eye-to-hand coordination, and superior memory. But the long-term effects of gaming on a key cognitive function called temporal visual selective attention—the capacity to distinguish between important and irrelevant information within a rapid stream of visual stimuli—has never been studied.

Here, researchers show for the first time that expert players of real-time strategy games have faster information processing, allocate more cognitive power to individual visual stimuli, and allocate limited cognitive resources between successive stimuli more effectively through time. These findings in Frontiers in Human Neuroscience suggest that playing such games can cause long-term changes in the brain and lead to an improvement in temporal visual selective attention.

"Our aim was to evaluate the long-term effect of experience with action real-time strategy games on temporal visual selective attention," says author Dr. Diankun Gong, Associate Professor in the Ministry of Education Key Laboratory for Neuroinformation at the University of Electronic Science and Technology of China.

"In particular, we wanted to reveal the time course of cognitive processes during the attentional blink task, a typical task used by neuroscientists to study visual selective attention."

Attentional blink is the tendency of focused observers to "blink"—that is, to fail to properly register—a visual stimulus if it appears so quickly after a previous stimulus that cognitive processing of the first hasn't finished. In a typical blink task, human subjects are shown a stream of digits and letters in quick succession (with 100 ms intervals) and asked to press a button each time they see one of two target letters (for example D and M).

People often "blink" a second target if it appears within 200-500 ms of the first, and electroencephalograms (EEGs) suggest that this is due to competition for cognitive resources between the first stimulus—with the need to encode it in working and episodic memory, and to select the appropriate response—versus the second. In other words, people often fail to register M because brain resources are temporarily used up by the ongoing need to process any D shown more than 200 ms and less than 500 ms earlier.

To study the effect of gaming on temporal visual selective attention, Gong and colleagues selected 38 volunteers, health young male students from the University of Electronic Science and Technology. Half of the volunteers were expert players of the typical action real-time strategy game League of Legend, where teammates work together to destroy the towers of an opposing team. They had played the game for at least two years and were masters, based on their ranking among the top 7% of players. The others were beginners, with less than six months experience of the same game, and ranked among the bottom 30-45%. All volunteers were seated in front of a screen and tested in a blink task, with 480 trials over a period of approximately 2 h. The greater a volunteer's tendency to "blink" targets, the less frequently he would press the correct button when one of the two targets appeared on the screen, and the worse he did overall in the task.

The volunteers also wore EEG electrodes on the parietal (i.e. sides and top) region of their scalp, allowing the researchers to measure and localize the brain's activity throughout the experiment. These electrodes recorded Event-Related Potentials (ERPs), tiny electric potentials (from -6 to 10 μV) that last from 0 to 800 ms after each non-blinked stimulus, and which represent the neural processes for registering and consolidating its memory. The researchers focused on the so-called P3b phase of the ERP, a peak between 200 and 500 ms after the stimulus, because previous research has shown that its timing and amplitude accurately reflects performance in the blink task: the later P3b occurs and the less pronounced it is, the more likely it is that a stimulus will be "blinked".

"We found that expert League of Legend players outperformed beginners in the task. The experts were less prone to the blink effect, detecting targets more accurately and faster, and as shown by their stronger P3b, gave more attentional cognitive resources to each target," says coauthor Dr. Weiyi Ma, Assistant Professor in Human Development and Family Sciences at the University of Arkansas, USA.

"Our results suggest that long-term experience of action real-time strategy games leads to improvements in temporal visual selective attention: the expert gamers had become more effective in distributing limited cognitive resources between successive visual targets," says author Dr. Tiejun Liu. "We conclude that such games can be a powerful tool for cognitive training."

One hour of video gaming can increase the brain's ability to focus

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More information: Xianyang Gan et al, Action Real-Time Strategy Gaming Experience Related to Increased Attentional Resources: An Attentional Blink Study, Frontiers in Human Neuroscience (2020). DOI: 10.3389/fnhum.2020.00101

Journal information: Frontiers in Human Neuroscience 

Provided by Frontiers 

Study: Money can't buy love – or friendship

by Bert Gambini, University at Buffalo

Credit: CC0 Public Domain

While researchers have suggested that individuals who base their self-worth on their financial success often feel lonely in everyday life, a newly published study by the University at Buffalo and Harvard Business School has taken initial steps to better understand why this link exists.


"When people base their self-worth on financial success, they experience feelings of pressure and a lack of autonomy, which are associated with negative social outcomes," says Lora Park, an associate professor of psychology at UB and one of the paper's co-authors.

"Feeling that pressure to achieve financial goals means we're putting ourselves to work at the cost of spending time with loved ones, and it's that lack of time spent with people close to us that's associated with feeling lonely and disconnected," says Deborah Ward, a UB graduate student and adjunct faculty member at the UB's psychology department who led the research on a team that also included Ashley Whillans, an assistant professor at Harvard Business School, Kristin Naragon-Gainey, at the University of Western Australia, and Han Young Jung, a former UB graduate student.

The findings, published in the journal Personality and Social Psychology Bulletin, emphasize the role of social networks and personal relationships in maintaining good mental health and why people should preserve those connections, even in the face of obstacles or pursuing challenging goals.

"Depression and anxiety are tied to isolation, and we're certainly seeing this now with the difficulties we have connecting with friends during the COVID-19 pandemic," says Ward. "These social connections are important. We need them as humans in order to feel secure, to feel mentally healthy and happy. But much of what's required to achieve success in the financial domain comes at the expense of spending time with family and friends."

Ward says it's not financial success that's problematic or the desire for money that's leading to these associations.

At the center of this research is a concept psychologists identify as Financial Contingency of Self-Worth. When people's self-worth is contingent on money, they view their financial success as being tied to the core of who they are as a person. The degree to which they succeed financially relates to how they feel about themselves—feeling good when they think they're doing well financially, but feeling worthless if they're feeling financially insecure.

The research involved more than 2,500 participants over five different studies that looked for relationships between financial contingency of self-worth and key variables, such as time spent with others, loneliness and social disconnection. This included a daily diary study that followed participants over a two-week period to assess how they were feeling over an extended time about the importance of money and time spent engaged in various social activities.

"We saw consistent associations between valuing money in terms of who you are and experiencing negative social outcomes in previous work, so this led us to ask the question of why these associations are present," says Ward. "We see these findings as further evidence that people who base their self-worth on money are likely to feel pressured to achieve financial success, which is tied to the quality of their relationships with others."

Ward says the current study represents the beginning of efforts to uncover the processes at work with Financial Contingency of Self-Worth.

"I hope this is part of what becomes a longer line of research looking at the mechanisms between valuing money and social-related variables," says Ward. "We don't have the final answer, but there is a lot of evidence that pressures are largely playing a role."


Explore further

Staking self-worth on the pursuit of money has negative psychological consequences
More information: Deborah E. Ward et al, Can't Buy Me Love (or Friendship): Social Consequences of Financially Contingent Self-Worth, Personality and Social Psychology Bulletin (2020). DOI: 10.1177/0146167220910872

Journal information: Personality and Social Psychology Bulletin

Provided by University at Buffalo 

Analysis: Household cleaning products effective against coronavirus

by Dr Lena Ciric, The Conversation

Credit: Syda Productions/Shutterstock

COVID-19 has only been around for a few months, so at this point scientists don't know that much about it. But more is being learned every day. We now know, for example, it can live on surfaces for up to nine days and survives in the air for a few hours. We also now know that the virus particles are shed through saliva and fluids coughed up from the lungs. And that the virus can also be shed from our faeces.

It's easy for an infected person to spread the virus particles through coughing, touching other people or leaving the virus on surfaces. Undoubtedly, hand-washing after being in public spaces is key to reduce the spread of COVID-19. But what should we be doing in our homes to eliminate it?

Two recent studies have investigated how long coronaviruses survive on different surfaces. The research looked at a number of different viruses including SARS-CoV-2—the coronavirus that has caused COVID-19. And it found that the survival times varied according to the type of surface.

The virus survived for longest on stainless steel and plastic—for up to nine days. The shortest survival times of one day was for paper and cardboard.

The amount of virus particles during this time does reduce, but it's worrying that the particles can last for days rather than hours or minutes on a surface. So, how good are the cleaning products already in your cupboards at killing SARS-CoV-2? There is some good news in the list below.

Soap and water

Soap and water are your first line of defence to remove the virus from surfaces. Soap interferes with the fats in the virus shell and lift the virus from surfaces and this is then rinsed off by water. Of course, you also need to wash your hands when you come in from the shops and wash your food as normal.

Bleach

The active ingredient in bleach—sodium hypochlorite—is very effective at killing the virus. Make sure you leave the bleach to work for 10-15 minutes then give the surface a wipe with a clean cloth. The bleach works by destroying the protein and what's known as the ribonucleic acid (RNA) of the virus—this is the substance that gives the blueprint for making more virus particles when you become infected. Be sure to use the bleach as directed on the bottle.

Table of time surviving in air and on surfaces. Credit: Lena Ciric

Surgical spirit

Surgical spirit is mostly made up of the alcohol ethanol. Ethanol has been shown to kill coronaviruses in as little as 30 seconds. Like bleach, the alcohol destroys the protein and RNA that the virus is made up of. Moisten a cloth with some neat surgical spirit and rub it over a surface. This will evaporate and you will not need to wipe it off.

Surface wipes

The active ingredient in surface wipes in an antiseptic –- usually benzalkonium chloride. AKA QUATS The wipes work by physically removing germs through the pressure you apply when you use them, and the germs then attach to the wipe.

They also leave a layer of the antiseptic on the surface that works to kill germs. The antiseptic works well on bacteria as well as on coronaviruses that infect mice and dogs—but it seems to make no difference to the spread of human coronavirus. Antiseptics work by disrupting the fats in pathogen cells, but SARS-CoV-2 does not contain many fats. So far, there is no evidence that antiseptics can kill human coronaviruses.

Hand sanitisers

A word of warning though about hand sanitisers. The main ingredient in hand sanitisers that will kill SARS-CoV-2 is ethanol, the alcohol in surgical spirit. But its concentration in the sanitiser is very important –- it has to be over 70 % or it will not kill the virus effectively.

One thing you can also do is make sure you air out the spaces you are spending time in regularly. An infected person will produce thousands of tiny droplets which contain the virus every time they cough. SARS-CoV-2 can survive in the air for up to three hours. So by opening the window, you can remove and disperse the droplets and reduce the amount of virus in the air—which will reduce the risk of infection for others.

We are living in uncertain times but it's reassuring to know that we have some weapons we can use to fight COVID-19 in our homes. The bottom line: keep washing your hands, use 70% hand sanitiser, dust off the bleach and open a window to let in the spring air.

Review examines how building design can influence disease transmission

by Andy Fell, UC Davis

Credit: CC0 Public Domain

Social distancing has Americans mostly out of the places they usually gather and in their homes as we try to reduce the spread of COVID-19. But some buildings, such as hospitals and grocery stores, have to remain open, and at some point, most of us will go back to the office or workplace. What is the role of building design in disease transmission, and can we change how we design the built environment to make it healthier? 

Those questions are addressed in a review just published in the journal mSystems by David Coil, project scientist, and Professor Jonathan Eisen at the UC Davis Genome Center and School of Medicine; and colleagues at the Biology and the Built Environment Center, University of Oregon.

Among the simplest suggestions for healthier buildings: opening windows to improve air circulation and opening blinds to admit natural daylight.

While more research needs to be done on the effect of sunlight on SARS-CoV-2 indoors, "Daylight exists as a free, widely available resource to building occupants with little downside to its use and many documented positive human health benefits," the authors write.

We spend almost all of our daily lives inside human-built environments whether homes, vehicles or workplaces. Built environments provide lots of opportunities for people to come into contact with viruses and bacteria—through air flow, from surfaces and also from the way buildings make us interact with each other.

So far, the only documented route of transmission of SARS-CoV-2 is directly from person to person. But viruses also settle on surfaces, which can become heavily contaminated quite quickly. How long SARS-CoV-2 survives on surfaces is still up for debate. Estimates range from a couple of hours to a few days, depending on the material and conditions. Regularly cleaning surfaces and thorough handwashing are important.

Air flow and humidity

Viral particles are too small to be blocked by HEPA and MERV air filters, but ventilation strategies can still play a role in reducing disease transmission, the authors write. Increasing the amount of air flowing in from outside and the rate of air exchange can dilute virus particles indoors. This can include "perimeter ventilation"—opening a window, when outdoor temperatures allow it. However, high air flow could also stir up settled particles and put them back in the air—and it also uses more energy.

Virus particles like drier air, so maintaining a high relative humidity can help. Virus-bearing droplets get bigger in humid air, meaning they settle out more quickly and don't travel as far. Humidity also seems to interfere with the lipid envelope around viruses such as SARS-CoV-2. Too much humidity, however, can promote mold growth.
Modern buildings are generally designed to promote social mixing—from open plan living areas in homes to open offices where many workers share space. By promoting interaction and chance encounters, these layouts are thought to generate more creativity and teamwork. At the same time, they are probably also really great for spreading viruses around.

It may not be practical in the short term to make big changes in office layout. But understanding how layout and the ways people use shared spaces affect disease transmission could help in developing effective social distancing measures and making decisions about when people can go back to work.


Explore further

Hopes for pandemic respite this spring may depend upon what happens indoors
More information: Leslie Dietz et al, 2019 Novel Coronavirus (COVID-19) Pandemic: Built Environment Considerations To Reduce Transmission, mSystems (2020). DOI: 10.1128/mSystems.00245-20
Provided by UC Davis