Tuesday, July 26, 2022

Professor, Indigenous rights activist question why Pope was gifted a headdress

After the long-anticipated apology from the Pope in Maskwacis Alta., Monday, Grand Chief of the Confederacy of Treaty 6 First Nations Wilton Littlechild presented the Holy Father with a headdress.



© Guglielmo Mangiapane/Reuters
After delivering a long-awaited apology Monday, Pope Francis was presented with a traditional headdress by Chief Wilton Littlechild in Maskwacis, Alta.

But not everyone is applauding Littlechild's gesture.

After Pope Francis's apology, Littlechild — a former commissioner of the TRC — placed the headdress on the Pontiff's head, over his papal zucchetto.

The pope donned the regalia briefly before having it removed by his staff.

Samson Cree elder John Crier supports Littlechild's decision to gift the headdress to the Pope.

"The giving of the headdress is honouring a man as the honourary chief and leader in a community. So, in doing that it actually adopted him as one of our leaders in the community," said Crier.

"It's an honouring of the work that he has done and it also is recognizing from the community that here's a man that belongs to our tribe."


Related video: Pope 'deeply sorry' for 'colonizing mentality' of many Christians
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The headdress donned by the Pope, the war bonnet, is held in high regard.

In 1987, when John Paul II visited Canada he met with Indigenous leaders and urged the church's solidarity with Indigenous peoples in Canada. Yet, Pope Francis is the first Pontiff to receive a war bonnet on a visit to Canada.

Riley Yesno is a Anishinaabe writer and Indigenous rights activist based in Toronto. She says allowing the Pope to be held in such high regard is frustrating.

"The church is here because it didn't act very honourably and the church continues not to act very honourably."

Yesno says she believes Indigenous people have been gracious to the Pope but, neither the Pope nor the Catholic church has returned the gesture.

"We're gifting things to the Pope and the Pope is not returning these [gestures] on the list of things that are actually meant to happen."

Niigaan Sinclair, professor of Indigenous Studies at University of Manitoba, says allowing prominent people to take part in significant Indigenous traditions can devalue their meaning.

"To give our most sacred items to those who, perhaps demonstrate goodwill, but don't deliver on the promises is just very upsetting, and it's also very degrading to our own ceremonial items."

Sinclair says although many viewed the papal visit and the gifted headdress as a turning point, there is still pain in the community.

"It is, at times, a very complicated day. It's not a day to celebrate. It's a day to realize that the traumas are still ongoing in our community and to sit to feel that pain."

Pope's apology doesn't acknowledge church's role as 'co-author' of dark chapter: Murray Sinclair

Apology fails to recognize 'full role of the church in the residential school system,' former senator says



Rachel Bergen · CBC News · Posted: Jul 26, 2022 
Former senator Murray Sinclair was the chair of the Truth and Reconciliation Commission from 2009 to 2015. He says the apology the Pope delivered Monday for the role Catholics played in Canada's residential school system was lacking. 
(Tyson Koschik/CBC)

The former Manitoba senator who chaired the Truth and Reconciliation Commission of Canada says there's a "deep hole" in the apology issued by Pope Francis Monday for the role Catholics played in Canada's residential school system.

Murray Sinclair says the historic apology, although meaningful to many residential school survivors and their families, fell short of Call to Action 58 in the final report.

It specifically called on the Pope to issue an apology "for the Roman Catholic Church's role in the spiritual, cultural, emotional, physical, and sexual abuse of First Nations, Inuit, and Métis children in Catholic-run residential schools."

In a written statement Tuesday, Sinclair said the intent was that survivors would not only hear remorse, "but an acceptance of responsibility for what they were put through at the hands of the church and other institutions."

While he called it a "historic apology," he said the Pope's statement "has left a deep hole in the acknowledgement of the full role of the church in the residential school system, by placing blame on individual members of the church."

Pope Francis delivered the apology Monday in Alberta at the site of the former Ermineskin residential school, one of the largest in Canada, as he started what he called his "penitential pilgrimage."

Pope Francis bows his head during a service at the Sacred Heart Church of the First Peoples in Edmonton on Monday as part of his papal visit across Canada. He apologized for the role of many Christians in residential schools, which doesn't go far enough, says Sinclair. (Nathan Denette/The Canadian Press)

"I ask forgiveness, in particular, for the ways in which many members of the church and of religious communities co-operated, not least through their indifference, in projects of cultural destruction and forced assimilation promoted by the governments of that time, which culminated in the system of residential schools," he said.

Sinclair said it's important to highlight that the Catholic Church was not just an agent of the state, but "a lead co-author of the darkest chapters in the history of the land."
Pope's residential school apology prompts mixed emotions from Manitoba survivors'We won't forget': Manitoba residential school survivors respond to Pope Francis' apology

Sinclair says Catholic leaders who were driven by the Doctrine of Discovery — a 15th-century papal edict that justified colonial expansion by allowing Europeans to claim Indigenous lands as their own — as well as other church beliefs and policies enabled the government of Canada, and pushed it further in its work to commit what the TRC called the cultural genocide carried out on Indigenous people in Canada.

That was often "not just a collaboration, but an instigation," he said.

"There are clear examples in our history where the church called for the government of Canada to be more aggressive and bold in its work to destroy Indigenous culture, traditional practices and beliefs," Sinclair's statement said.

"It was more than the work of a few bad actors — this was a concerted institutional effort to remove children from their families and cultures, all in the name of Christian supremacy."
Time for action

Sinclair says reconciliation requires action, and the Catholic Church must work to assist in restoring culture, beliefs and traditions destroyed through assimilation.

"For the children and descendants of survivors, it is not enough that you have stopped abusing them," he said. Rather, the church must help them recover, and "as well as commit to never doing this again."

Students and staff at the Fort Alexander residential school are shown in an archival photo. Sinclair says there are clear examples in Canadian history where the Church called for the government of Canada to be more aggressive in its work to destroy Indigenous culture, traditional practices and beliefs. (National Commission for Truth and Reconciliation archives)

The Pope will continue his pilgrimage throughout the week to meet with First Nations, Métis and Inuit survivors in Quebec and Nunavut. Sinclair hopes the pontiff will take his words to heart.

"There is a better path that the church — and all Canadians — can indeed follow: taking responsibility for past actions and resolving to do better on this journey of reconciliation."
Pope Francis apologizes for forced assimilation of Indigenous children at residential schools'I am deeply sorry': Full text of residential school apology from Pope Francis

Support is available for anyone affected by their experience at residential schools or by the latest reports.

A national Indian Residential School Crisis Line has been set up to provide support for former students and those affected. People can access emotional and crisis referral services by calling the 24-hour national crisis line: 1-866-925-4419.

Mental health counselling and crisis support is also available 24 hours a day, seven days a week through the Hope for Wellness hotline at 1-855-242-3310 or by online chat at www.hopeforwellness.ca.

ABOUT THE AUTHOR
Rachel Bergen is a journalist for CBC Manitoba and previously reported for CBC Saskatoon. Email story ideas to rachel.bergen@cbc.ca


CANADA: What Pope Francis left out of residential school apology



Pope Francis prays at a gravesite at the Ermineskin Cree Nation Cemetery in Maskwacis, Alta., during his papal visit across Canada on Monday, July 25, 2022. Pope Francis delivered a historic apology to survivors of the country's residential school system, the majority of which were operated by the Catholic Church. THE CANADIAN PRESS/Nathan Denette

Prior to his visit, Indigenous leaders made specific calls about what they wanted to see in the apology and where they hoped it would lead

OTAWA — Pope Francis delivered a historic apology on Monday to survivors of Canada's residential schools. The majority of those government-funded institutions, in which thousands of Indigenous children suffered abuse and neglect, were run by the Catholic Church.

In the lead-up to the Pope's visit, Indigenous leaders made specific calls about what they wanted to see in the apology and where they hoped it would lead to next. 

Here's what was missing:

A revocation of the Doctrine of Discovery

The Assembly of First Nations has been among the loudest bodies calling for the renouncement of the 14th-century policy. 

It was a decree from the Vatican that countries including Canada used to justify the colonization of Indigenous lands. 

The AFN says the doctrine ignores Indigenous sovereignty and continues to have legal impacts today. 

After Pope Francis's apology, delivered before an audience of survivors and others in Maskwacis, Alta., the pontiff faced a shout from the crowd to renounce the doctrine. 

An apology on behalf of the Roman Catholic Church as an institution

In his apology, the pontiff requested forgiveness "for the evil committed by so many Christians against the Indigenous Peoples." 

Murray Sinclair, who served as the chair of the Truth and Reconciliation Commission of Canada, said the pope's apology "left a deep hole" by failing to recognize the role the church itself played in the residential school system and instead "placing blame on individual members."

"It was more than the work of a few bad actors — this was a concerted institutional effort to remove children from their families and cultures, all in the name of Christian supremacy," Sinclair said in a statement Tuesday.

The TRC had listed a papal apology as one of its 94 calls to action.

Cody Groat, a professor at Western University and member of Six Nations of the Grand River in southern Ontario, says Pope Francis's earlier apology to an Indigenous delegation that travelled to see him in Rome was found lacking for a similar reason — placing blame on individuals rather than on the institution. 

Groat, whose grandparents attended a residential school operated by the Anglican Church, says people are going to see the language and terms the pontiff used in Monday's apology in different ways, adding he feels it's an improvement from the spring. 

"When you use remarks such as apologizing on behalf of the Christian faith, it perhaps acknowledges more of a broader incident that happened within a long history of colonialism." 

Any mention of sexual abuse — or genocide

The Truth and Reconciliation Commission, in its call for a papal apology, said it should address the Catholic Church's role in the "spiritual, cultural, emotional, physical, and sexual abuse" of Indigenous children at residential schools. 

Pope Francis said children suffered "physical, verbal, psychological and spiritual abuse," but did not mention sexual abuse.

Groat says the pontiff's words would have been carefully vetted before he delivered them and believes leaving out sexual abuse was a conscious effort. 

"That is going to be something that is called out by a lot of people," he said. 

"Not seeing Pope Francis directly acknowledge or apologize for sexual abuse, this is something that again, will be have to be followed up on."

Also absent from the pontiff's apology was the word "genocide." The commission concluded in its 2015 final report that Canada's residential school system amounted to a "cultural genocide." 

A promise to release documents and artifacts

One of the outstanding calls the Vatican and Catholic entities in Canada are facing is to release more documents related to the operation of residential schools, and to return Indigenous artifacts. 

The news last year that ground-penetrating radar had located what are believed to be hundreds of unmarked graves at former residential school sites across Western Canada underscored the need for governments and Church authorities to turn over records that could help identify those who died, advocates and Indigenous leaders say. 

Evelyn Korkmaz, a residential school survivor who attended St. Anne's residential school, noted the pope's apology didn't mention anything about handing over of church-held documents, which she said are desperately needed. 

"These documents have our history," she said. "These documents hold the identification of these children. It would give their families and loved ones closure. Everybody needs closure in order to heal and move on. And this is all we're asking, is for those documents to be released. They belong here in Canada. They belong to us."

The Métis National Council had also called for artifacts held in the Vatican, which were taken from Métis people and communities, to be returned. 

A commitment to reparations and compensation

The pontiff's apology and visit to Canada comes as the Catholic Church is facing criticism over not fulfilling the financial commitments it has made to survivors. 

One of the main points of contention is over a "best efforts" fundraising campaign that 48 Catholic entities signed on to as part of compensating survivors under the Indian Residential Schools Settlement Agreement struck in 2006. 

Of a stated $25-million goal for the fundraising effort, less than $4 million was raised before a judge ruled in 2015 that the entities were free from their obligations. 

Last September, the Canadian Conference of Catholic Bishops announced it would pledge $30 million to reconciliation-related initiatives over five years. Before Pope Francis's arrival, the bishops announced that dioceses had contributed $4.6 million to the effort so far. 

Some survivors and Indigenous leaders have said the pontiff's apology should be followed by additional commitments to reparations or restitutions. 

Cindy Blackstock, an advocate for child welfare and executive director of the First Nations Child and Family Caring Society of Canada, shared what she called a "to-do" list on social media to follow the apology. 

It included: "Ensuring the church (not parishioners) provides reparations for residential school survivors, and the estates of children who died." 

This report by The Canadian Press was first published July 26, 2022

Stephanie Taylor, The Canadian Press


Victims rights advocate Kennedy calls for resignation of Hockey Canada leaders

Former NHL player and victims rights advocate Sheldon Kennedy has called for the resignation of Hockey Canada president and chief executive officer Scott Smith, his leadership team and the organization's board of directors as scrutiny of the organization's handling of sexual abuse allegations involving its players continues.


© Provided by The Canadian PressVictims rights advocate Kennedy calls for resignation of Hockey Canada leaders

Kennedy posted his demand on Twitter in a statement responding to Hockey Canada's "action plan" released Monday to combat toxic culture.

"The same people with a new plan expecting the same results is the definition if insanity," Kennedy said in the statement, ending it with "enough is enough already."

Kennedy's statement came after the end of Tuesday's round of parliamentary hearings investigating Hockey Canada's handling of sexual assault allegations involving past world junior team players.

Kennedy said in a recent interview with The Canadian Press that a July 11 open letter from Hockey Canada, promising reforms and the reopening of an investigation into a 2018 allegation of group sexual assault, was "a good first step."

"The followup? They should be able to speak with their actions," he added. "I'm hopeful that they will.''

He made it clear Tuesday that he believes Hockey Canada hasn't done enough.

"Giving my 26 yrs of advocating for victims, I cant sit idle any longer," he said in a tweet attached to his statement.

Kennedy has been a voice for victims following his own experience being abused by then-coach Graham James in junior hockey.

Hockey Canada's action plan building on the open letter includes the implementation by the end of September of a centralized tracking and reporting system for abuse complaints. It said the results will be published annually to "hold Hockey Canada accountable.''

The organization will publish an annual social responsibility report, which will include information on complaints received at both the national team and subnational levels and a scorecard based on "key performance indicators.'' Hockey Canada said it was in the process of identifying the measures to be included in the scorecard.

Hockey Canada did not say what data on the complaints will be made public in the report, but historical allegations of sexual assault will not be included.

The parliamentary hearings will continue Wednesday, with Smith being among those scheduled to testify.

This report by The Canadian Press was first published July 26, 2022.

The Canadian Press

A more balanced public health approach is needed for e-cigarette use

Researchers at Rutgers seek balanced policies to ensure the devices are available for those who want to kick the cigarette smoking habit but don’t serve as a gateway to smoking or nicotine addiction

Peer-Reviewed Publication

RUTGERS UNIVERSITY

Rutgers researchers are calling for a balanced approach to examining recent trends in adult e-cigarette use.

 

Julia Chen-Sankey, an assistant professor in the Department of Health Behavior, Society and Policy at the Rutgers School of Public Health, and Michelle T. Bover-Manderski, an instructor in the Department of Biostatistics and Epidemiology at Rutgers, said that while there are clear health concerns with e-cigarette use, particularly the adoption by those who previously hadn’t used tobacco products, there also are potential benefits that can’t be ignored.

 

The Rutgers researchers published an invited commentary in the Journal of the American Medical Association (JAMA) Network Open, reviewing new data on the trend of e-cigarette use among U.S. adults. Chen-Sankey and Bover-Manderski, who are also researchers at the Rutgers Center for Tobacco Studies, discussed the need for a public health approach that balances the risks with the potential of e-cigarettes to facilitate cessation of combustible cigarette smoking by adults. 

 

You reviewed a study that raised important questions about e-cigarette use among U.S. adults. What did that study find, and what questions has it raised about public health policy?

 

Chen-Sankey: The paper was on recent trends in adult e-cigarette use in the United States in 2017, 2018 and 2020. Among the findings was the observation that while current e-cigarette use – defined as vaping in the previous 30 days – by young adults ages 18 to 20 years declined between 2018 and 2020, it increased in other age groups. Daily e-cigarette use among current users also increased.

 

But perhaps most alarming, e-cigarette use increased significantly for people who never smoked combustible cigarettes. It also decreased among combustible cigarette smokers attempting to quit – despite the potential that e-cigarettes have in helping people to stop smoking.

 

Bover-Manderski: In terms of how these conflicting findings should be applied to health policy, there is a need to balance concerns about the dangers of e-cigarette use among young people new to tobacco products with the potential benefits that e-cigarettes may have for people who want to stop smoking combustible cigarettes.

 

How can we strike that balance?

 

Chen-Sankey: There are several policy advances and strategies that may be helpful in ensuring that the net public health benefit of e-cigarette use is not eclipsed by its harm. For instance, the recent authorization of e-cigarette products by the U.S. Food and Drug Administration (FDA) through its Premarket Tobacco Product Applications pathway may help to establish public trust in authorized e-cigarette products.

 

The FDA is also likely to authorize certain e-cigarettes as modified-risk tobacco products, which may help encourage smokers to see e-cigarettes as a tool to stop smoking combustible cigarettes.

 

Bover-Manderski: Additionally, to boost combustible cigarette smokers’ acceptance of using e-cigarettes for smoking cessation, public health education and mass media communication strategies should focus on evidence-based results pertaining to the reduced harm associated with switching to e-cigarettes.

 

Why do you think some adults who smoke combustible cigarettes have turned away from vaping as a means of quitting?

 

Chen-Sankey: Over the past five years or so, e-cigarette products have become less appealing to combustible smokers interested in quitting but more appealing to people who have never smoked. A few factors can help explain this discouraging pattern.

 

For one, local and national policies intended to reduce the use of e-cigarettes among youths may simultaneously reduce adult smokers’ interest in and use of e-cigarettes when attempting to quit. Additionally, the media may have altered smokers’ understanding of vaping because of the substantially higher volume of media coverage of vaping risks for youths compared with the potential benefits of vaping for adult combustible cigarette smokers.

 

Bover-Manderski: It’s also likely that public health groups and health care professionals may have emphasized the risks of vaping for youths over the potential benefits for adults who use combustible tobacco.

 

A bright spot in the research is a substantial decline in e-cigarette use by young adults ages 18 to 20. What accounts for this dip?

 

Chen-Sankey: The discrepancy may be associated with the Tobacco to 21 Act that restricted the sale of tobacco and nicotine delivery products, including e-cigarettes, to this age group nationwide starting in January 2020. Another potential explanation for the disproportional reduction is national restrictions on certain flavored cartridge-based e-cigarettes implemented in February 2020, a policy that may have considerably reduced the appeal of e-cigarettes among young people.

 

Bover-Manderski: And of course, we can’t overlook COVID-19 pandemic-related lockdowns and social-distancing requirements, which may have limited this group’s opportunities to use e-cigarettes in social or group settings.

Ant colonies behave like neural networks when making decisions

Peer-Reviewed Publication

ROCKEFELLER UNIVERSITY

Ant colony 

IMAGE: A COLONY OF ANTS EVACUATE THEIR NEST FOLLOWING A TEMPERATURE PERTURBATION. view more 

CREDIT: DANIEL KRONAUER

Temperatures are rising, and one colony of ants will soon have to make a collective decision. Each ant feels the rising heat beneath its feet but carries along as usual until, suddenly, the ants reverse course. The whole group rushes out as one—a decision to evacuate has been made. It is almost as if the colony of ants has a greater, collective mind.  

A new study suggests that indeed, ants as a group behave similar to networks of neurons in a brain.   

Rockefeller’s Daniel Kronauer and postdoctoral associate Asaf Gal developed a new experimental setup to meticulously analyze decision-making in ant colonies. As reported in the Proceedings of the National Academy of Sciences, they found that when a colony evacuates due to rising temperatures, its decision is a function of both the magnitude of the heat increase and the size of the ant group.  

The findings suggest that ants combine sensory information with the parameters of their group to arrive at a group response—a process similar to neural computations giving rise to decisions. 

“We pioneered an approach to understand the ant colony as a cognitive-like system that perceives inputs and then translates them into behavioral outputs,” says Kronauer, head of the Laboratory of Social Evolution and Behavior. “This is one of the first steps toward really understanding how insect societies engage in collective computation.”  

A new paradigm  

At its most basic level, decision-making boils down to a series of computations meant to maximize benefits and minimize costs. For instance, in a common type of decision-making called sensory response thresholding, an animal has to detect sensory input like heat past a certain level to produce a certain costly behavior, like moving away. If the rise in temperature isn’t big enough, it won’t be worth it.  

Kronauer and Gal wanted to investigate how this type of information processing occurs at the collective level, where group dynamics come into play. They developed a system in which they could precisely perturb an ant colony with controlled temperature increases. To track the behavioral responses of individual ants and the entire colony, they marked each insect with different colored dots and followed their movements with a tracking camera.  

As the researchers expected, colonies of a set size of 36 workers and 18 larvae dependably evacuated their nest when the temperature hit around 34 degrees Celsius. This finding makes intuitive sense, Kronauer says, because “if you become too uncomfortable, you leave.”  

However, the researchers were surprised to find that the ants were not merely responding to temperature itself. When they increased the size of the colony from 10 to 200 individuals, the temperature necessary to trigger the decision to vacate increased. Colonies of 200 individuals, for example, held out until temperatures soared past 36 degrees. “It seems that the threshold isn’t fixed. Rather, it’s an emergent property that changes depending on the group size,” Kronauer says.  

Individual ants are unaware of the size of their colony, so how can their decision depend on it? He and Gal suspect that the explanation has to do with the way pheromones, the invisible messengers that pass information between ants, scale their effect when more ants are present. They use a mathematical model to show that such a mechanism is indeed plausible. But they do not know why larger colonies would require higher temperatures to pack up shop. Kronauer ventures that it could simply be that the larger the colony’s size, the more onerous it is to relocate, pushing up the critical temperature for which relocations happen.  

In future studies, Kronauer and Gal hope to refine their theoretical model of the decision-making process in the ant colony by interfering with more parameters and seeing how the insects respond. For example, they can tamper with the level of pheromones in the ants’ enclosure or create genetically altered ants with different abilities to detect temperature changes. “What we’ve been able to do so far is to perturb the system and measure the output precisely,” Kronauer says. “In the long term, the idea is to reverse engineer the system to deduce its inner workings in more and more detail.”  

Scientists expand entomological research using genome editing


Research team develops functional annotation workflow for genome sequencing of insects

Peer-Reviewed Publication

HIROSHIMA UNIVERSITY

Overview of the functional annotation workflow, Fanflow4Insects 

IMAGE: FANFLOW4INSECTS CONSISTS OF THREE PIPELINES. view more 

CREDIT: HIDEMASA BONO, HIROSHIMA UNIVERSITY (CC-BY 4.0)

Genome sequencing, where scientists use laboratory methods to determine a specific organism’s genetic makeup, is becoming a common practice in insect research. A greater understanding of insect biology helps scientists better manage insects, both those that are beneficial to the ecosystem and those that damage the food supply and threaten human health by carrying diseases.

Researchers have developed a work-flow method, called Fanflow4Insects, that annotates gene functions in insects. In functional annotation, scientists collect information about a gene's biological identity. The team’s new method uses transcribed sequence information as well as genome and protein sequence databases. With Fanflow4Insects, the team has annotated the functional information of the Japanese stick insect and the silkworm, including gene expression as well as sequence analysis. The functional annotation information that their workflow provides will greatly expand the possibilities of entomological research using genome editing.

The team, with scientists from Hiroshima University, Tokyo University of Agriculture and Technology, and RIKEN Center for Integrative Medical Sciences, has published their Fanflow4Insects method on June 27 in the journal Insects.

Insects are so diverse and abundant that scientists need a way of studying them on a large scale. This is what led scientists to begin work on sequencing the genome of insects. As of May 2022, scientists had decoded and registered the genomes of around 3000 insect species. They are also using long-read sequencing technology to further accelerate the pace of insect genome sequencing.

Next-generation sequencing has made it easier for researchers to decode the genomes of numerous insects along with their transcript sequences. However, the biological interpretation of these sequences remains a primary bottleneck of transcriptome analysis. The transcriptome is the sum of an organism’s RNA molecules. Transcriptome analysis is an important first step in functional annotation, which serves as an important clue for selecting genome editing targets.

Because some insects have genomes larger than the human genome, the difficult process of whole-genome sequencing is even more complicated. So scientists are using transcriptome sequencing with next-generation sequencing technology, also called RNA sequencing, as a tool for evaluating large genome-size insects. With this powerful tool, scientists can efficiently identify tens of thousands of possible genes in a specific tissue by assembling tens of millions of reads. They then assemble the gene sequences into transcriptional units for identification. But this type of analyses is dependent upon the scientists having access to comprehensive datasets and their functional annotation. Databases do exist, but they are unable to keep pace with the increase in insect genome sequencing.

As transcriptome analysis becomes more popular, many research groups are running their own pipelines, with the information regarding the transcription units from various studies being reported on a study-by-study basis. These pipelines are sets of algorithms used to processes the genome sequencing data. But scientists need a way to integrate the functional annotation from all the different groups doing this type of research into public databases.

In this current study, the research team used their newly developed Fanflow4Insects to create a functional annotation pipeline for the silkworm. Then the researchers also tested Fanflow4Insects for the transcriptomes of the Japanese stick insect. “Functional annotation is one of the most important processes to accelerate the selection of target genes once genome or transcriptome of the target organism is decoded. The functional annotation information obtained by the workflow Fanflow4Insects will greatly expand the possibilities of entomological research using genome editing,” said Hidemasa Bono, a professor with the Graduate School of Integrated Sciences for Life at Hiroshima University, and the first and corresponding author on the paper.

The Fanflow4Insects workflow for insects has been openly developed on GitHub, and is freely accessible. In conjunction with the functional annotation derived from expression, the data from Fanflow4Insects can be applied to the comparative study of insects with distinct phenotypes. “Using Fanflow4Insects, we are going to annotate insects that produce useful substances. The ultimate goal of this study is to make it possible to design molecular networks in insects using computer simulation,” said Bono.

###

The research team includes Hidemasa Bono, Hiroshima University; Takuma Sakamoto and Hiroko Tabunoki, Tokyo University of Agriculture and Technology; and Takeya Kasukawa, RIKEN Center for Integrative Medical Sciences.

This research was funded by a Japan Society for the Promotion of Science Kakenhi grant, an open innovation platform for industry–academia co-creation (COI-NEXT), Japan Science and Technology Agency, and the ROIS-DS-JOINT.

About Hiroshima University

Since its foundation in 1949, Hiroshima University has striven to become one of the most prominent and comprehensive universities in Japan for the promotion and development of scholarship and education. Consisting of 12 schools for undergraduate level and 4 graduate schools, ranging from natural sciences to humanities and social sciences, the university has grown into one of the most distinguished comprehensive research universities in Japan.
English website: https://www.hiroshima-u.ac.jp/en

Historical mistrust in government, health care industry contributes to COVID-19 vaccine hesitancy for African Americans

MU researcher studies social, structural determinants of health that feed vaccine hesitancy, worsen health disparities for African Americans.


UNIVERSITY OF MISSOURI-COLUMBIA

image: Vaccine 
Credit: University of Missouri

COLUMBIA, Mo. – While African Americans have disproportionately higher COVID-19 infection and mortality rates compared to white individuals, they also have disproportionately lower COVID-19 vaccination rates, which is partially fueled by vaccine hesitancy.

In an effort to address health disparities that negatively impact African Americans, MU’s Wilson Majee led a study to better understand the factors that contribute to COVID-19 vaccine hesitancy among African Americans. He found compounding factors, including historical mistrust in government and personal experiences of racism within the health care system, contribute to COVID-19 vaccine hesitancy for African Americans.

Majee interviewed church leaders, lifestyle coaches and participants of Live Well by Faith, a community faith-based wellness program run by the Boone County Health Department that promotes healthy living and addresses chronic health conditions in predominantly African American communities in Boone County, Missouri. Both historical mistrust in government and personal experiences of racism within the health care system were common themes among African American community members for not wanting to receive the COVID-19 vaccine.

“The Tuskegee Syphilis Study was repeatedly mentioned as a popular example of unethical medical treatment toward African Americans by the federal government, and once that trust is lost, it can be hard to regain even as time goes on,” said Majee, an associate professor in the MU School of Health Professions. “One respondent mentioned the common reminder from the federal government of never forgetting the tragic events of September 11, 2001, yet African Americans are expected to forget the unethical research practices and the history of injustice and racism from their own federal government.”

Majee also told the story of another respondent who reflected on his own personal experience in the health care industry after he tested positive for COVID-19.

“This elderly man went to the hospital but was sent home, and after his health declined, he went back to the hospital but was sent back home again,” Majee said. “When he went back a third time, he was told they had made a mistake and he was given a hospital bed so he could be monitored, and he could not help but wonder if his experience would have been different if he was not Black?”

Other factors contributing to COVID-19 vaccine hesitancy included how fast the vaccine was developed, a lack of Black physicians providing the vaccines and misinformation spread on social media.

Majee added social determinants of health, including that African Americans tend to be poorer and have less access to education, health care and healthy foods, as well as structural determinants of health, including that African Americans tend to be affected by racism in the housing, education, employment and health care industries, all compound together to contribute to worse health outcomes for African Americans.

“African Americans are more likely to have lower-income, in-person jobs at crowded places that cannot accommodate work-from-home or social distancing, so they are more likely to be exposed to and infected by COVID-19,” Majee said. “Combine that with African Americans already being poorer and less likely to be able to afford quality health insurance, the historical mistrust in government and personal negative experiences with the health care industry, and you quickly see how all these factors start to work together to negatively impact health outcomes for African Americans.”

Community wellness programs like Live Well by Faith play a key role in helping to address these inequities, Majee said. Receiving accurate information about the COVID-19 vaccine from trusted community members, such as African American church leaders and lifestyle coaches, played a big role in promoting positive health outcomes.

“African American members of the congregation at Black churches believed in the information they were receiving because it was coming from people they trusted that looked like themselves,” Majee said. “The key about the Live Well by Faith program is that is it rooted in the community, and we saw it was helpful in getting more African Americans to receive the COVID-19 vaccine.”

Majee’s main research goal is to find ways in which those with power, including local, state and federal governments, church leaders, researchers and adult role models, can distribute resources that engage vulnerable populations in their communities.

“My passion is to empower people in resource-limited communities by listening to their ideas and allocating resources to develop interventions that meet the needs of struggling people,” Majee said. “There is a great need to elevate the health of minorities, as the disparities are huge and will continue to grow if we fail to act now.”

“The past is so present: Understanding COVID-19 vaccine hesitancy among African American adults using qualitative data” was published in Journal of Racial and Ethnic Health Disparities. Co-authors on the study include MU’s Adaobi Anakwe, Kelechi Onyeaka and Idethia Harvey.

Health Care Experiences of Patients Discontinuing or Reversing Prior Gender-Affirming Treatments

Key Points

Question  What are the health care experiences of adults undergoing medical and/or surgical detransition?

Findings  In this qualitative study, 28 adults with heterogenous gender identities were interviewed about their experiences of detransition, including their health care encounters when discontinuing or reversing gender-affirming medical and/or surgical care. A majority of respondents reported no decisional regrets regarding prior gender-affirming interventions; however, participants frequently discussed health care avoidance, clinician stigma, and experiencing clinicians who lacked detransition-related clinical knowledge.

Meaning  These findings suggest that clinicians may be insufficiently knowledgeable to meet the needs of this population, and further research and clinical guidance are required to better support people who detransition after pursuing gender-affirming health care.

Abstract

Importance  Medical education, research, and clinical guidelines are available to support the initiation of gender-affirming care for transgender and nonbinary people. By contrast, little is known about the clinical experiences of those who discontinue or seek to reverse gender-affirming medical or surgical interventions due to a change in gender identity, often referred to as detransition.

Objective  To examine the physical and mental health experiences of people who initiated medical or surgical detransition to inform clinical practice.

Design, Setting, and Participants  Using constructivist grounded theory as a qualitative approach, data were collected in the form of in-depth interviews. Data were analyzed using an inductive 2-stage coding process to categorize and interpret detransition-related health care experiences to inform clinical practice. Between October 2021 and January 2022, individuals living in Canada who were aged 18 years and older with experience of stopping, shifting, or reversing a gender transition were invited to partake in semistructured virtual interviews. Study advertisements were circulated over social media, to clinicians, and within participants’ social networks. A purposive sample of 28 participants who discontinued, shifted, or reversed a gender transition were interviewed.

Main Outcomes and Measures  In-depth, narrative descriptions of the physical and mental health experiences of people who discontinued or sought to reverse prior gender-affirming medical and/or surgical interventions.

Results  Among the 28 participants, 18 (64%) were assigned female at birth and 10 (36%) were assigned male at birth; 2 (7%) identified as Jewish and White, 5 (18%) identified as having mixed race and ethnicity (which included Arab, Black, Indigenous, Latinx, and South Asian), and 21 (75%) identified as White. Participants initially sought gender-affirmation at a wide range of ages (15 [56%] were between ages 18 and 24 years). Detransition occurred for various reasons, such as an evolving understanding of gender identity or health concerns. Participants reported divergent perspectives about their past gender-affirming medical or surgical treatments. Some participants felt regrets, but a majority were pleased with the results of gender-affirming medical or surgical treatments. Medical detransition was often experienced as physically and psychologically challenging, yet health care avoidance was common. Participants described experiencing stigma and interacting with clinicians who were unprepared to meet their detransition-related medical needs.

Conclusions and Relevance  This study’s results suggest that further research and clinical guidance is required to address the unmet needs of this population who discontinue or seek to reverse prior gender-affirming interventions.

READ ON:  Health Care Experiences of Patients Discontinuing or Reversing Prior Gender-Affirming Treatments | Health Disparities | JAMA Network Open | JAMA Network