Tuesday, March 23, 2021

"JUST THE FACTS MA'AM"
US trial reports AZ Covid-19 jab safe and
effective, with no blood clot link
22 March 2021 

The US Phase III trial of AstraZeneca’s Covid-19 vaccine has demonstrated an efficacy of 79% at preventing symptomatic Covid-19, and 100% efficacy at preventing severe disease and hospitalisation.

The Phase III trial showed AZ’s Covid-19 vaccine to be reliably effective among those aged 65 years and over, in whom the jab demonstrated an efficacy of 80%. 



Credit: AstraZeneca








The US Phase III trial of AstraZeneca’s Covid-19 vaccine has demonstrated an efficacy of 79% at preventing symptomatic Covid-19, and 100% efficacy at preventing severe disease and hospitalisation.

A specific review of thrombotic events and cerebral venous sinus thrombosis during the trial, conducted by the independent safety monitoring board and an independent neurologist, found no increased risk of thrombosis among the 21,583 trial participants receiving at least one dose of the vaccine.

The review findings come after several European countries paused rollouts of the AstraZeneca-Oxford University vaccine, following reports of blood clotting events in a small number of those vaccinated.

The European Medicines Agency last week concluded that the vaccine is “safe and effective” following an investigation into a potential link between the jab and blood clots, while the World Health Organisation urged countries to continue administering the vaccine.

The randomised Phase III trial also showed the vaccine to be reliably effective among those aged 65 years and over, in whom the jab demonstrated an efficacy of 80%.

The results among older participants confirm the vaccine’s efficacy in those aged over 65. Earlier this year, numerous European countries decided to limit the AstraZeneca vaccine to under-65s, citing a lack of evidence for the vaccine in the older age group. Several of these countries, including Germany and France, have since approved the jab for use in older people in response to the publication of further safety and efficacy data.

In the Phase III study, around 20% of participants were aged 65 or older, and approximately 60% had co-morbidities associated with an increased risk for progression of severe Covid-19, such as diabetes, severe obesity or cardiac disease.

The trial involved a total of 32,449 participants – two-thirds of whom received the vaccine – across 88 sites in the US, Peru and Chile.

University of Rochester School of Medicine professor Ann Falsey, one of the principal investigators for the trial, said: “These findings reconfirm previous results observed in AZD1222 trials across all adult populations but it’s exciting to see similar efficacy results in people over 65 for the first time.

“This analysis validates the AstraZeneca Covid-19 vaccine as a much-needed additional vaccination option, offering confidence that adults of all ages can benefit from protection against the virus.”

The new data, which AstraZeneca will continue to analyse, is set to be submitted to the US Food and Drug Administration for Emergency Use Authorisation in the coming weeks. The vaccine has already been approved for emergency use in the UK, European Union and many other countries globally.

AstraZeneca executive vice president of biopharmaceuticals R&D Mene Pangalos said: “These results add to the growing body of evidence that shows this vaccine is well tolerated and highly effective against all severities of Covid-19 and across all age groups.

“We are confident this vaccine can play an important role in protecting millions of people worldwide against this lethal virus. We are preparing to submit these findings to the US Food and Drug Administration and for the rollout of millions of doses across America should the vaccine be granted US Emergency Use Authorisation.”






expert reaction to press release from AstraZeneca announcing interim data on safety and efficacy from the US trial of the Oxford-AstraZeneca COVID-19 vaccine

AstraZeneca has published a press release announcing that the Oxford-AstraZeneca COVID-19 vaccine US Phase III trial met primary efficacy endpoint in preventing COVID-19 at interim analysis.

 

Dr Peter English, Retired Consultant in Communicable Disease Control, Former Editor of Vaccines in Practice Magazine, Immediate past Chair of the BMA Public Health Medicine Committee, said:

“This press release provides more good news about vaccines in general and the Oxford/AstraZeneca vaccine in particular.1  It is consistent with previous studies of the vaccine.

“Part of the importance of the study it describes is that it will support the emergency use authorisation which is reportedly soon to be (if not already) being applied for in the United States.

“The press release describes a large phase III trial conducted in the US, Peru and Chile, with 32,449 participants of all ages and of different ethnicities, two-thirds of whom were given the active vaccine, and the other third a placebo vaccine (no doubt the full peer-reviewed papers will tell us what the placebo contained).  It gives us information from an interim analysis of data from these trials.

“The press release tells us that there were 141 cases of symptomatic disease in participants, and that the vaccine showed the following characteristics:

“79% vaccine efficacy at preventing symptomatic COVID-19

“100% efficacy against severe or critical disease and hospitalisation

“Comparable efficacy result across ethnicity and age, with 80% efficacy in participants aged 65 years and over”

“This is a large study, so these results can be expected to be robust.  They could be expected to be even more so if there were more cases to compare between the groups; but 141 is still a substantial number of cases.

“The press release also tells us that:

“Amongst participants in the interim analysis, approximately 79% were white/Caucasian, 8% black/African American, 4% native American and 4% Asian, and 22% of participants were Hispanic.

“Approximately 20% of participants were 65 years and over, and approximately 60% had co-morbidities associated with an increased risk for progression of severe COVID-19, such as diabetes, severe obesity or cardiac disease.”

“The full, peer-reviewed paper will no-doubt provide more detailed information on the efficacy in these subgroups; but with only 141 cases, the numbers in different subcategories may be too small to detect small efficacy differences between subgroups, if they exist.  Nevertheless, it is reassuring to read that there was no obvious difference between them.

“Note that the vaccine showed “100% efficacy against severe or critical disease and hospitalisation”.  In other words, NO vaccine recipients had severe or critical disease, or was hospitalised (at least, not with Covid-19), so there is no way to distinguish between efficacy at preventing different subcategories of more severe disease, and we don’t know if the study distinguished between levels of severity greater than mild-to-moderate disease.

“This also means that there were no cases of the more severe forms of disease in people aged 65 years and over – in this age group, the vaccine had 100% efficacy at preventing such disease; 80% efficacy against any symptomatic disease in this age group. (The same concept applies to other subgroups.)

“The report also shows that there were no safety concerns.  It looked particularly at clotting (“thrombotic”) events and found no excess of cases in vaccine recipients.  It was unable to shed further light on the specific clotting event that has raised concerns recently, cerebral venous sinus thrombosis (CVST), other than to confirm that such events are very rare.  No CVST events were detected in either arm of the study, we are told, so it was unable to confirm or refute the suggestion that this particular condition may be more common following vaccination.

“The fact that there were no such events, however, does emphasise the rarity of this condition, and that even if there were to be an increase in the relative risk following vaccination, the absolute risk remains very low.

“(I have yet to see any explanation as to why this particular clotting event (CVST) might be more common post-vaccination when other clotting events are not.  If you look for enough rare events, one of them will, by chance, be more common in people who were vaccinated in the study population you used, without this being a causal relationship but just chance.  My strong suspicion is that this will prove to be the case for CVST.)

“The press release does refer to the prime-boost interval, stating:

“This AstraZeneca-led US Phase III trial included two doses administered at a four week interval. Previous trials have shown that an extended interval of up to 12 weeks demonstrated greater efficacy, which was also supported by immunogenicity data. This evidence suggests administration of the second dose with an interval longer than four weeks could further increase efficacy and accelerates the number of people who can receive their first dose.”

“Decades of vaccine research tell us that a longer prime-boost interval is likely to increase vaccine efficacy, and, as they say this is supported by immunogenicity data; but it should be noted that the study the press release is describing used a four-week prime-boost interval.  There is nothing in the press release to suggest that the study examined vaccine efficacy with different prime-boost intervals.

“One thing that is not clear in this press release is whether the study provided any information on the real-world efficacy of the vaccine against different variants of the virus.  There is no information on whether genomic typing of the cases was undertaken, the prevalence of different variants in the study population, or the dates during which the data were collected (which would allow some inferences to be drawn on variant prevalence and thus vaccine efficacy against the variants).  We know from other work that the vaccine seems to be highly effective against many variants, in particular the more transmissible B.1.1.7 variant; but we do not know if the study will add to our knowledge on this.”

References

  1. AstraZeneca Press Office. AZD1222 US Phase III trial met primary efficacy endpoint in preventing COVID-19 at interim analysis. AstraZeneca Press Release 2021; Updated 22 Mar 2021; Accessed: 2021 (22 Mar): (https://www.astrazeneca.com/content/astraz/media-centre/press-releases/2021/astrazeneca-us-vaccine-trial-met-primary-endpoint.html).
  2. Steenhuysen J. Exclusive: AstraZeneca to seek U.S. authorization for COVID-19 vaccine this month or early next – sources. Reuters 2021; Updated 13 Mar 2021; Accessed: 2021 (22 Mar): (https://www.reuters.com/article/us-health-coronavirus-astrazeneca/exclusive-astrazeneca-to-seek-u-s-authorization-for-covid-19-vaccine-this-month-or-early-next-sources-idINKBN2B42JN).

 

Dr Andrew Garrett, Executive VP, Scientific Operations, ICON Clinical Research, said:

“This is clearly stated as an AstraZeneca-led trial, and it more closely follows the large phase III vaccine trials reported by other sponsors.  In this respect it is a solid 30,000 plus participant study with a placebo control, and a simple 4 week dosing interval, such that interpretation is more straightforward than previous Oxford/AZ vaccine trials.  It has a good age mix with more than 6,000 participants aged >65 years and also wide ethnic representation.  Interim efficacy is clearly stated as being 79% against symptomatic COVID-19 and 100% effective against severe disease.  Detailed numbers are not provided at this time and the lower confidence limit is not stated.  Importantly the trial provides further support for efficacy in the elderly (80%) where previous clinical trial data, other than immunological data, had been lacking.  The study randomized two subjects to receive vaccine for every subject that received placebo providing a large safety database of 20,000 plus participants who received active vaccine.  As described, this has been used to investigate the potential association of the vaccine with thrombotic events and specifically cerebral venous sinus thrombosis, of which there were no cases detected.  Overall it was reported that there was no increased risk of thrombosis.  These data are therefore timely in further addressing any safety concerns that could undermine vaccine uptake.

“The trial is directed at generating data to support emergency use in the US but also provides valuable data to other countries – both confirming efficacy using a 4-week dosing interval and re-enforcing vaccine safety.”

 

Prof Stephen Evans, Professor of Pharmacoepidemiology, London School of Hygiene & Tropical Medicine, said:

“These results are not surprising given what we know now.  The US regulatory authorities are reluctant, even in a pandemic, to rely totally on data obtained outside the US, so this trial was done to provide convincing evidence of efficacy and safety in a sufficiently large number of US patients.  The benefits of these results will mainly be for the rest of the world where confidence in the AZ vaccine has been eroded, largely by political and media comment.  Once that happens, reporting of adverse effects becomes very biased and confidence can spiral downwards.  The rest of the world that will rely on this low-cost vaccine may be able to procced with vaccinating their populations.

“Vaccine development and rollout should be an international collaboration rather than nationalistic fervour whether in favour of, or against, a particular vaccine.  Assessment should be based on science alone.

“It is important also to realise that the “headline” efficacy numbers are valid for comparison between the groups in a trial, but great care is needed in comparisons between trials.  The way that events are assessed and counted as well as the context of a trial means that exact values for any between trial comparison are uncertain, not only because of statistical uncertainty, but also because of these other factors.

“It is clear this vaccine has very good efficacy (remember that 60% was, prior to any trials being started, regarded as a good target), and that this efficacy does not show a notable decline at older ages.  This was expected and the speculation that it was ineffective (or “quasi-ineffective”) at older ages was totally unjustified.

“This is good news for the global community and one hopes that any political statements around this good news are avoided.”

 

 

AstraZeneca press release: https://www.astrazeneca.com/content/astraz/media-centre/press-releases/2021/astrazeneca-us-vaccine-trial-met-primary-endpoint.html

University of Oxford press release: https://www.ovg.ox.ac.uk/news/usa-chile-and-peru-interim-trial-data-show-oxford-astrazeneca-vaccine-is-safe-and-highly-effective

 

 

All our previous output on this subject can be seen at this weblink:

www.sciencemediacentre.org/tag/covid-19

 

 

Declared interests

Dr Peter English: “No conflicts of interest to declare.”

Dr Andrew Garrett: “I am employed by ICON which is a Contract Research Organization.  ICON provides pharmaceutical services to the pharmaceutical and biotechnology industries. ICON conducts clinical trials on behalf of Sponsors, including vaccine trials. I am a member of the UK Statistical Authority’s (UKSA) Research Accreditation Panel. I have received one dose of the Oxford/AstraZeneca vaccine as part of the UK vaccination program.”

Prof Stephen Evans: “No conflicts of interest.  I am funded (one day per week) by LSHTM.  They get funding from various companies, including Astra Zeneca and GSK but I am not funded by them, I have no involvement in obtaining funding from them and I am not an investigator on any grants obtained from them.  I am the statistician to the ‘meta-Data Safety and Monitoring Board’ for CEPI.  I am paid for my attendance at those meetings and will be paid expenses for travel if that occurs.  I am a participant in the Oxford/Astra Zeneca trial, and on 13th January 2021 learnt I had received the active vaccine.”

Doctors march in Myanmar to protest coup
BY JOHN BOWDEN - THE HILL 03/21/21 

© Getty Images


Doctors and other medical professionals took to the streets in Myanmar's second-largest city on Sunday to protest the military coup that ousted the country's civilian government last month.

Reuters reported that protests occurred in multiple towns across the country including Mandalay, where hundreds of demonstrators joined the doctor-led protest. Engineers in the city also held their own "no-human strike," and lined up signs in the street with anti-military messages, according to The Associated Press

At least one person was killed, according to multiple news sources, after being shot by a member of the military. Thousands of protesters have been arrested since the coup early last month, but figures on arrests Sunday were not immediately available.

Military officials have alleged that last year's election, which incumbent state counselor Aung San Suu Kyi's party won, was fraudulent. The country's electoral commission has rejected this finding, but military officials have nonetheless promised new elections while imprisoning top government officials and employing harsh tactics against demonstrators.

The State Department called on Myanmar's military to "restore the democratically elected government, release all those who have been unjustly detained, lift the restrictions on telecommunications, and refrain from violence" earlier this month.

Monday, March 22, 2021

First female U.S. vice president Harris congratulates Tanzania's first woman president Hassan

WASHINGTON (Reuters) - U.S. Vice President Kamala Harris on Saturday congratulated Tanzania's new president Samia Suluhu Hassan, the first woman to hold that office, and said the United States was ready to strengthen ties between the two countries.
© Reuters/STRINGER FILE PHOTO: Tanzania's new President Samia Suluhu Hassan takes oath of office following the death of her predecessor John Pombe Magufuli at State House in Dar es Salaam

© Reuters/JONATHAN ERNST FILE PHOTO: U.S. Vice President Harris delivers a keynote address to the House Democratic Caucus virtually on camera from the White House in Washington

Harris, the first woman and first person of color to serve as U.S. vice president, made the comment in a posting on Twitter.

"Sending best wishes to @SuluhuSamia following her swearing in as Tanzania's new President - the first woman to hold the office. The United States stands ready to work with you to strengthen relations between our countries," she wrote.

Hassan, who had been vice president since 2015, on Friday urged the country to unite https://www.reuters.com/article/idUSL1N2LH099 and avoid pointing fingers after the death of John Magufuli, her COVID-19 sceptic predecessor.

The U.S. Trade Representative's office is leading U.S. efforts to forge a new trade and investment partnership with the East African Community, a regional organization that includes Burundi, Kenya, Rwanda, South Sudan, Tanzania and Uganda.

Total trade between the two countries was $462 million in 2019. U.S. foreign direct investment (FDI) in Tanzania was $1.5 billion in 2019, a 5.2% increase from 2018, according to U.S. government data.

(Reporting by Andrea Shalal; editing by Grant McCool)
VULCAN PORNO
Thousands flock to Iceland's erupting volcano

Thousands of curious onlookers have flocked to an erupting volcano in Iceland to marvel at the hypnotic display of glowing red lava, the bravest of them grilling hot dogs and marshmallows over the smoldering embers.

© Jeremie RICHARD The volcano lies just 40 kilometres west of Reykjavik

The eruption of a fissure near Mount Fagradalsfjall, which began late Friday, was the first in the same volcanic system in about 900 years.

© Jeremie RICHARD Visitors gather as Icelandic volcano subsides following eruption

The volcano is located only about 40 kilometres (25 miles) from the capital Reykjavik and can be reached after a 90-minute hike from the nearest road.

"It's absolutely breathtaking," says Ulvar Kari Johannsson, a 21-year-old engineer who spent his Sunday visiting the scene.

© Jeremie RICHARD Sunday hikers watch the lava flowing from the erupting Fagradalsfjall volcano

"It smells pretty bad. For me what was surprising was the colours of the orange: much, much deeper than what one would expect," he tells AFP.

The incandescent lava bubbles and spurts from a small cone in the Geldingadalur valley, piling up in the basin and slowly turning a thick black as it cools.

Some 300,000 cubic metres (10.5 million cubic feet) of lava have poured out of the ground so far, according to experts, although the eruption is considered relatively small and controlled.

"For me it's the heat that really surprised me. When we approached the lava flowing on the ground, the temperature rose by 10-15 degrees and our faces flushed," says Emilie Saint-Mleux, a French exchange student in Iceland who came with two friends.

"It reminds you a little of a barbecue in summer," jokes her friend Lucille Fernemont.

Access to the site was blocked in the first hours after the eruption. Authorities then lifted the roadblocks but discouraged visits, but by Saturday afternoon visitors were allowed -- under strict guidelines.
© Jeremie RICHARD The eruption of the fissure near Mount Fagradalsfjall began late Friday

"We are just here to look after the people and see that everything is okay. And just watch that the people are not going too close to the lava and asking them step back," explains Atli Gunnarsson, a 45-year-old police officer, donning a yellow hardhat with a gas mask in hand.

© Alain BOMMENEL Icelandic volcano erupts

Rescue teams also had to help dozens of freezing and exhausted people find their way back to the road on Sunday in the dark as weather conditions deteriorated.

A small recurring beep can be heard around the emergency crews. They're carrying devices that measure gas pollution, especially sulphur dioxide, which can pose a danger to health and even be fatal. 
© Icelandic Coast Guard A no-fly zone was established in the area around the volcano.

Early Monday, authorities again blocked the site due to high levels of gas pollution.

- Rare opportunity -

This is the first volcanic eruption on the Reykjanes peninsula in more than 800 years, and it has been more than 900 years since the Krysuvik volcanic system, to which Fagradalsfjall belongs, has erupted.

© Jeremie RICHARD It has been more than 900 years since the Krysuvik volcanic system, to which Fagradalsfjall belongs, has erupted

While eruptions are common in Iceland, with one taking place about every five years on average, they usually occur far from populated zones, in inaccessible areas. Others are too dangerous to allow public



This time, the curious can inspect the lava up close after a six-kilometre (four-mile) hike from a road near the fishing port of Grindavik, the closest populated town with 3,500 inhabitants, not far from the famed tourist destination, the Blue Lagoon geothermal spa.

By Sunday, the throngs of hikers trodding across the volcanic moss had already left a visible trail to the Geldingadalur valley.

Others chose to break their piggybanks for a spot in the many helicopters flying over the volcano at the weekend.


While the number of tourists in Iceland has plunged because of the pandemic -- tourism usually accounts for more than eight percent of the economy -- the island is trying to kickstart the industry.

It recently opened its doors to any international travellers who can prove they have either been fully vaccinated against Covid-19 or recovered from the illness.

It remains to be seen however if Iceland will be able to capitalise on the volcano.

According to experts, the eruption could die out quickly, possibly within a few days.

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A 6,000-year-dormant Icelandic volcano just erupted — and it’s awesome

The eruption near Reykjavik followed months of earthquakes, and led to beautiful orange and red skies.

By Anya van Wagtendonk Mar 20, 2021, 

The March 20 eruption near Mount Fagradalsfjall in Iceland.
 Vilhelm Gunnarsson/Getty Images

After months of earthquakes, a long-dormant volcano in the southwest of Iceland erupted on Friday night, leading to dramatic videos and splendid red skies near the country’s capital city.

According to the Icelandic Meteorological Office, the eruption near Mount Fagradalsfjall, about 20 miles southwest of Reykjavik, took place at 8:45 pm. Though considered small, the eruption created a fissure about 1,640 feet long, and spewed more than 10 million square feet of lava, sometimes in fountains reaching heights of more than 300 feet.



It was the first volcanic eruption in this part of Iceland — the Reykjanes Peninsula, home to Reykjavik, where most of the country’s residents live — in 781 years. And it was the first time this particular volcano had gone off in about 6,000 years.

The eruption, in the Geldinga Valley, was remote enough that evacuations were not necessary, and no structures were endangered.

“As of now it is not considered a threat to surrounding towns,” said Iceland’s prime minister, Katrín Jakobsdóttir, on Twitter on Friday night. “We ask people to keep away from the immediate area and stay safe.”

Experts warned residents to beware emissions of dangerous gases, including carbon dioxide and sulfur dioxide, and there were some resulting traffic jams. Drones were temporarily prohibited from flying over the area, to allow scientists first access, but flights in and out of the international Keflavik


 Airport have not been affected.

The head of emergency management in the country told people to close their windows and stay inside to avoid volcanic gas pollution, which could spread as far as Thorlákshöfn, a city about 30 miles south of Reykjavik.

But on Saturday, the meteorological office said, “Currently, gas pollution is not expected to cause much discomfort for people except close up to the source of the eruption.”


The eruption is ongoing, and could last for “a day or a month,” Magnús Tumi Gudmundsson, a geophysicist at the University of Iceland, told RÚV, the Icelandic National Broadcasting Service.

That makes this latest Icelandic geologic event starkly different than than the large-scale earthquake at the Eyjafjallajokull volcano in 2010, which caused more than 100,000 flights across Europe to be canceled for weeks afterwards as ash spread across northern Europe and Great Britain. That was described as the largest shutdown of airspace since WWII.

“The more we see, the smaller this eruption gets,” Páll Einarsson, a geophysicist at the University of Iceland, told the Associated Press on Saturday.

Despite the relatively small size, the eruption provided residents with unique views — and people across the region shared photos of the skies, as scientists set up a livestream of the flowing lava.



Iceland’s location makes it particularly susceptible to earthquakes — and eruptions


Iceland is no stranger to volcanic activity. There is usually an eruption every four or five years because the island is in a region that is particularly susceptible to seismic activity. The most recent one, in 2014, was at Holuhraun, a lava field in the Icelandic Highlands.

Earthquakes are a familiar experience, too; since 2014, the country registered between 1,000 and 3,000 earthquakes per year. But since December 2019, that number has dramatically increased, according to the New York Times; scientists are still working to understand why.

In the last week alone, Iceland experienced more than 18,000 earthquakes, with more than 3,000 on Sunday. At least 400 had taken place in the area of the volcano the day before the eruption — and that was a relatively calm day, according to state meteorologists.

“This is somewhat less seismic activity in comparison to previous mornings where the numbers have been around 1,000 earthquakes,” the meteorological office said.

Many of those earthquakes were undetectable to ordinary people, but some were of magnitude 3 and greater, so that they could be felt. The largest was a 5.7-magnitude quake on the morning of February 24, followed by a magnitude 5 tremor 30 minutes later.

“I have experienced earthquakes before, but never so many in a row,” Reykjavik resident Audur Alfa Ólafsdóttir told CNN earlier this month. “It is very unusual to feel the Earth shake 24 hours a day for a whole week. It makes you feel very small and powerless against nature.”

According to Thorvaldur Thórdarson, a professor of volcanology at the University of Iceland, the cause of this dramatic increase in seismic activity is still being studied.

“We are battling with the ‘why’ at the moment. Why is this happening?” he told CNN. “It is very likely that we have an intrusion of magma into the [Earth’s] crust there. It has definitely moved closer to the surface, but we are trying to figure out if it’s moving even closer to it.”

Icelanders were warned about possible volcanic activity as a result of the earthquakes beginning on March 3. Officials at the time did not expect the event to be life-threatening or affect property.

Iceland’s location along a series of tectonic plates — known as the Mid-Atlantic Ridge — has made it uniquely susceptible to activity.

As the Times’s Elian Peltier writes, “The country straddles two tectonic plates, which are themselves divided by an undersea mountain chain that oozes molten hot rock, or magma. Quakes occur when the magma pushes through the plates.”




Officials, including Justice Minister Áslaug Arna Sigurbjörnsdóttir, the Coast Guard, and first responders shared overhead images of bright lava spilling through the fissure.




And many Icelanders shared images on social media of the eruption’s aftermath, which cast an orange hue into the sky. At night, from certain angles, its glow merged with the famed green and blue of the northern lights.


Pop star Björk — perhaps Iceland’s most famous resident — was one of those expressing excitement about the historic event and ensuing beauty.

“YESSS !! , eruption !!” she wrote on Instagram on Friday. “We in iceland are sooo excited !!! we still got it !!! sense of relief when nature expresses herself !!!”
Amber Ruffin Puts The Spotlight On The Long History Of Anti-Asian Racism In The U.S.
Sarah Curran 
CTV ET
3/21/2021
© Photo by: Lloyd Bishop/Peacock/NBCU Photo Bank via Getty Images Amber Ruffin

Amber Ruffin is using her platform to highlight America's "long and well-documented" record of bigotry against Asian people.

During the latest episode of her late-night Peacock show, the comedian took a deep dive into the history of anti-Asian racism in the United States, including the recent spike in hate crimes.

RELATED: Olivia Munn Talks Stopping Asian Hate & Biden’s ‘Powerful’ Proclamation That U.S. Federal Buildings Fly Flags At Half-Mast To Mark Atlanta Massacre

"It's really impossible — Trump — to say — Trump — why something like that — Trump — would happen," Ruffin said. "But I do know that anti-Asian violence spiked after Trump and other Republicans started referring to the coronavirus as the 'China virus' and other racist terms."

She continued, "It doesn't surprise me that this kind of rhetoric would lead to an increase in violence. Partly because I have the common sense God gave a housefly, and partly because America has a long, violent history of scapegoating Asian people."

RELATED: Charles Melton Vows To ‘No Longer Remain Silent’ On Anti-Asian Hate Crimes

Ruffin went on to take a look back at America's lengthy record of anti-Asian racism, from the 1871 Chinese massacre in Los Angeles to the Chinese Exclusion Act of 1882, which barred Chinese immigrants.

"America does not get to hide from its racist past or present," she added.

RELATED: Daniel Dae Kim Calls On Other Communities To Speak Up Against Asian Hate During Time 100 Interview

"What we're not gonna do is act like white supremacy isn't at the root of all this," she added. "Contrary to everything this country was built on, white men don't get to decide who lives and who dies. White people don't get to decide our humanity."

Ruffin's comments come in the wake of Tuesday’s horrific shooting in Atlanta, which left eight people dead, the majority of them women of Asian descent, after a shooter targeted three different spas in the area.

ET Canada stands with the Asian community in working together to stop anti-Asian racism in Canada, the United States, and around the world to #StopAsianHate.

Canadians can stay informed by following community groups and leaders, including but not limited to: https://nextshark.com/,

If you or someone you know is experiencing hate-crimes related to xenophobic attacks in Canada you can file a report at: https://www.elimin8hate.org/fileareport.

Bystander intervention training to anti-Asian and xenophobic harassment is available at: ihollaback.org/bystanderintervention/


Why Asian women are uniquely vulnerable to violence in Canada and the U.S.

Emma Sandri
POSTMEDIA
3/20/2021

The intersection between race and gender has made Asian women uniquely vulnerable to violence, experts and advocates say in the wake of the killings of six Asian women in Atlanta, Georgia.

© Provided by National Post People hold a banner during a candlelight vigil in Garden Grove, California, on March 17, 2021 to unite against the recent spate of violence targeting Asians and to express grief and outrage after a shooting that left eight people dead in Atlanta, Georgia, including at least six Asian women.

The 21-year-old accused gunman, who is white, carried out his violent rampage at three spas on Tuesday, killing eight people.

A spokesperson for the Cherokee County Sheriff’s Department said the gunman confessed to the shootings and indicated that he had a sex addiction and “wanted to eliminate” the temptation the establishments represented to him.

Probe into killing of 6 Asian women, 2 others 'far from over,' Atlanta police say

While investigators have said it’s too early to say whether the gunman’s crimes were racially motivated, anti-Asian hate crimes have been on the rise, in both the U.S. and Canada, over the past year.


“Whether or not they were actually sex workers or self-identified under that label, we know that as massage workers, they were subjected to sexualized violence stemming from the hatred of sex workers, Asian women, working class people and immigrants,” wrote Red Canary Song , a grassroots collective of Asian and migrant sex workers, in response to the killings.

Sexism and racism not mutually exclusive

As Sunny Woan wrote in the Washington and Lee Journal for Civil Rights and Social Justice, Asian women are often fantasized as “small, weak, submissive and erotically alluring … existing solely to serve men and be sexually consumed by them.”

Over the last century, the media and the arts have continued to over-sexualize Asian women, while portraying them as meek and inferior — such as in the hit Broadway play, Miss Saigon, in which an underage sex worker in Vietnam falls in love with an American Marine — wrote Woan.
WHICH IS BASED ON THE OPERA MADAME BUTTERFLY ITSELF A WORK ABOUT AN AMERICAN IMPERIALIST AND AND ASIA WOMAN HIS LOVER WHOM HE ABANDONS AND SO SHE COMMITS SUICIDE

Russell Jeung, a professor of Asian American studies at San Francisco State University,
told NBC that the intersection of racism and sexism — including the stereotype that Asian women are subservient — has factored into the disproportionate impact of anti-Asian violence on women. In particular, Asian women have often been perceived as “easier targets.”

More than 68 per cent of reported incidents of anti-Asian harassment and violence (in America) have been from women,” said Sung Yeon Choimorrow , executive director of National Asian Pacific American Women’s Forum, in a statement on the Atlanta shootings. “Even before the pandemic and the racist scapegoating that came in its wake, AAPI ( Asian Americans and Pacific Islanders) women routinely experienced racialized misogyny.”








The ‘Shecession


Asian-owned businesses have been particularly hard hit by the pandemic, as lockdown restrictions have been compounded by racism.

In particular, politicians’ rhetoric has been blamed for fueling anti-Asian racism and business boycotts, such as president Donald Trump’s labelling of COVID-19 as the “Kung-flu” or “Wuhan virus.” Amy Go, president of the Chinese Canadian National Council for Social Justice, said that language has done “tremendous” harm to the Chinese-Canadian community.

“There’s so much pain and grief,” she told the Canadian Press about her initial reaction to the attack. “At the same time, as Asian Canadian women, none of us were surprised. There was no sense of shock. It was as if we knew this was coming … it just happened to be in Atlanta.”

Many Chinese businesses and restaurants experienced a drop in sales before the start of the pandemic, as customers opted to stay home — or buy from somewhere else — after hearing about the virus.

The pandemic has also been especially hard on Canadian women — with the economic recession being dubbed a “shecession.” When the pandemic first hit, women lost 62 per cent of the jobs shutdown in February and March 2020 — almost all in the service sector. Compared to white women, women of colour — including Asian women — have faced higher rates of unemployment during the pandemic.



According to Reuters , these women tend to work in some of the hardest-hit job sectors, such as retail and hospitality, and care for children or relatives. In particular, South Asian women have experienced the highest unemployment rates in the country over the summer, with 20 per cent of South Asian women aged 15 to 69 reporting they were without a job in July.

“The Asian women murdered yesterday were working highly vulnerable and low-wage jobs during an ongoing pandemic speaks directly to the compounding impacts of misogyny, structural violence and white supremacy,” said Phi Nguyen, a litigation director at Asian American Advancing Justice – Atlanta, in a statement .
Violence and harassment stoked by COVID-19

According to Statistics Canada , media outlets and police services have reported an increase in anti-Asian discrimination since the start of the pandemic — reminiscent of reactions to the 2009 SARS outbreak.

In May 2020, more than 43,000 Canadians submitted responses on how COVID-19 has impacted their perceptions of safety. Data from Statistics Canada shows that Canadians with Asian backgrounds were more likely to report noticing increased racial or ethnic harassment during the pandemic. In particular, Korean, Chinese and Filipino participants perceived that discriminatory incidents — such as harassment or attacks — were happening often or sometimes in their communities.

Among the women surveyed who were identified as visible minorities, 26 per cent reported feeling unsafe while walking alone after dark. The highest proportion of those who felt unsafe were Korean, Filipino and Chinese participants — the same groups who perceived an increase in harassment and attacks since the onset of COVID-19.

British Columbia has also surpassed any sub-national region in North America for having the most reported anti-Asian hate crime incidents “per Asian capita,” according to community-based reporting tool Project 1907 . Women have been disproportionately impacted in particular, and make up nearly 70 per cent of all reported incidents in the province.

“Just because we look Chinese or look Asian, we’re suddenly not Canadian,” Go told the Canadian Press .


 ABC News
Duration 2:05
Neighbors across the US are standing strong against anti-Asian American bias