Tuesday, August 24, 2021

 SUSTAINABLE AIR CONDITIONING

The combination of mask wearing and keeping windows open is best for reducing Covid-19 risk in cars, finds a new study


New research from the University of Surrey has confirmed that keeping car windows open to draw in fresh air is key to reducing the risk of contracting the virus in vehicle environments – but there are trade-offs

Peer-Reviewed Publication

UNIVERSITY OF SURREY

As the country prepares to live in a post-Covid-19 world and car travel – including taxi and car-sharing services that mix households – returns to normal, new research from the University of Surrey has confirmed that keeping car windows open to draw in fresh air is key to reducing the risk of contracting the virus in vehicle environments – but there are trade-offs.  

In a paper published by Environment International, Surrey's renowned Global Centre for Clean Air Research (GCARE) explored what motorists must consider to make sure their in-car environments are as Covid-secure as possible. 

The GCARE team used sensors to monitor pollution particles concentration, map how those particles varied during different settings in the vehicle and evaluate exposure dose per km of PM2.5 for three different ventilation settings (open window, air conditioning using fresh air, and air conditioning using air recirculation). The team also used sensors to monitor CO2 emission - a proxy used in the experiment for Covid-19. 

The GCARE researchers found that maintaining a continuous intake of fresh air by keeping the windows open – while also wearing a mask -- is the best way to guard against the transmission of Covid-19 --- but this increases occupants’ exposure to toxic air pollution particles.  

Motorists face a dilemma, since guarding against air pollution by keeping windows closed in turn aggravates the risk from Covid-19: the study found that the probability of Covid-19 transmission rate increased by 28.5 per cent when windows are closed and air recirculation is switched on.  

For the best chance of remaining safer from both Covid-19 and external air pollution, the GCARE team found that keeping the windows closed -- which mitigates air pollution particles -- while running air conditioning on ambient mode (drawing in fresh air from outside) to minimise exposure to Covid-19, is the optimal balance.  

Professor Prashant Kumar, lead author of the study, Associate Dean (International) and Founding Director of GCARE at the University of Surrey, said: 

"It's vital that the scientific community provides society with the data it needs so we can learn from the painful experience of the past two years.  

"Our research found that if your priority is to reduce the risk of contracting Covid-19, wearing a mask and keeping car windows open is the ideal approach." 

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Note to editors 

The research builds on GCARE's research into airborne transmission of COVID-19 and is supported by the Innovate UK funded project 'Pollution Guardian 2' under the Technology Strategy Board File Reference number 105725, the CO-TRACE (COvid-19 Transmission Risk Assessment Case studies - Education Establishments; EP/W001411/1) and the COVAIR (Is SARS-CoV-2 airborne and does it interact with particle pollutants?; EP/V052462/1) projects funded by the EPSRC under the COVID-19 call. 

Reference 

Kumar, P., Omidvarborna, H., Tiwari, A., Morawska, L., 2021. The nexus between in-car aerosol concentrations, ventilation and the risk of respiratory infection. Environment International, 106814. Link: https://doi.org/10.1016/j.envint.2021.106814 

About the University of Surrey 

The University of Surrey - a global community of ideas and people, dedicated to life-changing education and research. The University of Surrey is a research-intensive university committed to teaching and research excellence with a focus on practice-based education programmes, providing a world-class experience to its students who go on to make positive contributions to society. It is committed to working in partnership with students, businesses, government and communities in the discovery and application of knowledge. 

Record-breaking lithium-metal cell

Nickel-rich cathode and ionic liquid electrolyte enable extremely high energy density and good stability – researchers report in joule

Peer-Reviewed Publication

KARLSRUHER INSTITUT FÜR TECHNOLOGIE (KIT)

Record-breaking Lithium-metal Cell 

IMAGE: WITH A PROMISING COMBINATION OF CATHODE AND ELECTROLYTE, THE HIU RESEARCHERS AIM TO MAKE A VERY HIGH ENERGY DENSITY POSSIBLE. (PHOTO: AMADEUS BRAMSIEPE, KIT) view more 

CREDIT: AMADEUS BRAMSIEPE, KIT

Currently, lithium-ion batteries represent the most common solution for mobile power supply. In some applications, however, this technology reaches its limits. This especially holds for electric mobility, where lightweight and compact vehicles with large ranges are desired. Lithium-metal batteries may be an alternative. They are characterized by a high energy density, meaning that they store much energy per mass or volume. Still, stability is a problem, because the electrode materials react with conventional electrolyte systems.

Researchers of Karlsruhe Institute of Technology (KIT) and the Helmholtz Institute Ulm for Electrochemical Energy Storage (HIU) have now found a solution. As reported in Joule, they use a promising new combination of materials. A cobalt-poor, nickel-rich layered cathode (NCM88) reaches a high energy density. With the usually applied, commercially available organic electrolyte (LP30), however, stability leaves a lot to be desired. Storage capacity decreases with an increasing number of cycles. Professor Stefano Passerini, Director of HIU and Head of the Electrochemistry for Batteries Group, explains the reason: “In the electrolyte LP30, particles crack on the cathode. Inside these cracks, the electrolyte reacts and damages the structure. In addition, a thick mossy lithium-containing layer forms on the anode.” For this reason, the scientists used a non-volatile, poorly-flammable, dual-anion ionic liquid electrolyte (ILE) instead. “With the help of ILE, structural modifications on the nickel-rich cathode can be reduced significantly,” says Dr. Guk-Tae Kim from the Electrochemistry for Batteries Group of HIU.

Capacity Keeps 88 Percent after 1000 Cycles

The results: The lithium-metal battery with the NCM88 cathode and the ILE electrolyte reaches an energy density of 560 watt-hours per kilogram (Wh/kg) – based on the total weight of the active materials. Its initial storage capacity is 214 milliampere hours per gram (mAh g-1) of the cathode material. After 1000 cycles, 88 percent of the capacity are retained. The average Coulombic efficiency, i.e., the ratio between discharge and charge capacity, is 99.94 percent. As the battery is characterized by a high safety, the researchers have made an important step towards carbon-neutral mobility. (or)

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About the Helmholtz Institute Ulm

The Helmholtz Institute Ulm (HIU) was established in January 2011 by Karlsruhe Institute of Technology (KIT), Member of the Helmholtz Association, in cooperation with Ulm University. With the German Aerospace Center (DLR) and the Center for Solar Energy and Hydrogen Research Baden-Württemberg (ZSW), two other renowned institutions are involved in the HIU as associated partners. The international team of about 130 scientists at HIU works on the development of fundamentals of future energy storage systems for stationary and mobile use.

Original Publication (Open Access)

Fanglin Wu, Shan Fang, Matthias Kuenzel, Angelo Mullaliu, Jae-Kwang Kim, Xinpei Gao, Thomas Diemant, Guk-Tae Kim, and Stefano Passerini: Dual-anion ionic liquid electrolyte enables stable Ni-rich cathodes in lithium-metal batteries. Joule. Cell Press, 2021. DOI: 10.1016/j.joule.2021.06.014

https://doi.org/10.1016/j.joule.2021.06.014

More about HIU: https://hiu-batteries.de/en/

Contact for This Press Release

Sandra Wiebe, Press Officer, phone: +49 721 608-41172, email: sandra.wiebe@kit.edu

Being “The Research University in the Helmholtz-Association,“ KIT creates and imparts knowledge for the society and the environment. It is the objective to make significant contributions to the global challenges in the fields of energy, mobility and information. For this, about 9,600 employees cooperate in a broad range of disciplines in natural sciences, engineering sciences, economics, and the humanities and social sciences. KIT prepares its 23,300 students for responsible tasks in society, industry, and science by offering research-based study programs. Innovation efforts at KIT build a bridge between important scientific findings and their application for the benefit of society, economic prosperity, and the preservation of our natural basis of life. KIT is one of the German universities of excellence.

This press release is available on the internet at http://www.kit.edu/kit/english/press_releases.php

The photo can be downloaded at https://www.kit.edu/downloads/pi_bilder/2021_075_Rekordverdaechtige%20Lithium-Metall-Batterie_1.jpg and can be requested at presse@kit.edu or by phone +49 721 608-41105.

The photo may be used in the context given above exclusively.

 STAR TREKNOLOGY

Raising the steaks: First 3D-bioprinted structured Wagyu beef-like meat unveiled


Researchers at Osaka University use 3D-bioprinting to create structured cultured meat like the complex texture of Wagyu beef, which may provide an environmentally friendly and sustainable method for producing cultured meat alternatives


Peer-Reviewed Publication

OSAKA UNIVERSITY

Figure. 

IMAGE: SCHEME OF STRUCTURED WAGYU BEEF MEAT BY “3D PRINTING KINTARO-AME TECHNOLOGY” view more 

CREDIT: OSAKA UNIVERSITY

Osaka, Japan – Scientists from Osaka University used stem cells isolated from Wagyu cows to 3D-print a meat alternative containing muscle, fat, and blood vessels arranged to closely resemble conventional steaks. This work may help usher in a more sustainable future with widely available cultured meat. Wagyu can be literally translated into “Japanese cow,” and is famous around the globe for its high content of intramuscular fat, known as marbling or sashi. This marbling provides the beef its rich flavors and distinctive texture. However, the way cattle are raised today is often considered to be unsustainable in light of its outsized contribution to climate emissions. Currently, the available “cultured meat” alternatives only consist primarily of poorly organized muscle fiber cells that fail to reproduce the complex structure of real beef steaks.

Now, a team of scientists led by Osaka University have used 3D-Printing to create synthetic meat that looks more like the real thing. “Using the histological structure of Wagyu beef as a blueprint, we have developed a 3D-printing method that can produce tailor-made complex structures, like muscle fibers, fat, and blood vessels,” lead author Dong-Hee Kang says. To overcome this challenge, the team started with two types of stem cells, called bovine satellite cells and adipose-derived stem cells. Under the right laboratory conditions, these “multipotent” cells can be coaxed to differentiate into every type of cell needed to produce the cultured meat.

Individual fibers including muscle, fat, or blood vessels were fabricated from these cells using bioprinting. The fibers were then arranged in 3D, following the histological structure, to reproduce the structure of the real Wagyu meat, which was finally sliced perpendicularly, in a similar way to the traditional Japanese candy Kintaro-ame. This process made the reconstruction of the complex meat tissue structure possible in a customizable manner. “By improving this technology, it will be possible to not only reproduce complex meat structures, such as the beautiful sashi of Wagyu beef, but to also make subtle adjustments to the fat and muscle components,” senior author Michiya Matsusaki says. That is, customers would be able to order cultured meat with their desired amount of fat, based on taste and health considerations.

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The article, “Engineered whole cut meat-like tissue by the assembly of cell fibers using tendon-gel integrated bioprinting” was published in Nature Communications at DOI: https://doi.org/10.1038/s41467-021-25236-9

About Osaka University

Osaka University was founded in 1931 as one of the seven imperial universities of Japan and is now one of Japan's leading comprehensive universities with a broad disciplinary spectrum. This strength is coupled with a singular drive for innovation that extends throughout the scientific process, from fundamental research to the creation of applied technology with positive economic impacts. Its commitment to innovation has been recognized in Japan and around the world, being named Japan's most innovative university in 2015 (Reuters 2015 Top 100) and one of the most innovative institutions in the world in 2017 (Innovative Universities and the Nature Index Innovation 2017). Now, Osaka University is leveraging its role as a Designated National University Corporation selected by the Ministry of Education, Culture, Sports, Science and Technology to contribute to innovation for human welfare, sustainable development of society, and social transformation.

Website: https://resou.osaka-u.ac.jp/en

We need to have new strategies to deal with the new reality affected by global crises


Reports and Proceedings

ESTONIAN RESEARCH COUNCIL

B.Klasche 

IMAGE: BENJAMIN KLASCHE FROM THE SCHOOL OF GOVERNANCE, LAW AND SOCIETY AT TALLINN UNIVERSITY view more 

CREDIT: TALLINN UNIVERSITY

The thesis sets out with the observation that the current social science paradigms fail to adequately assess global crises in their totality and therefore fail to understand them. This is also due to the fact that these crises need to be classified as wicked problems, which constantly change their identity and constitution. Subsequently, attempts at governing those crises (e.g. the Migration Crisis, Coronavirus Crisis, Climate Crisis) fall short as they are based on an insufficient understanding of the crises.

„The main argument of the thesis is that by relying on a processual-relational approach, which conceives of the world as a web of ever-unfolding relations and thereby increases the complexity of the social world, we have a better chance at dealing with wicked problems in the form of global crises. The main difference of this approach to most other social science paradigms is the fact that it places primacy on relations instead of entities and accounts for a dynamic, always changing social reality,“ said Klasche and added: „I am, however, careful to suggest this approach as the answer to all questions and stress that it is particularly useful in this situation but almost unserviceable in other situations that require less abstraction.“

The thesis sets itself apart from other studies with its interdisciplinary focus that connects relational sociology with public administration and international relations and creates a dialogue with different pieces of knowledge of these disciplines. Based on this, it establishes the match of processual relationalism with the study of wicked problems. It further moves the theoretical and philosophical debates that relational sociologists have been having to a methodological and even empirical level and will be the foundation of research to come. On a more practical level, it urges policy-makers to stop breaking complex problems into smaller pieces and attempting to solve these without keeping the big picture in mind, and further always assume the failure of policies as the only possible outcome. However, the swift acceptance of failure is to be viewed positively, as it allows for the dismissal or modification of policies which eventually will help deal with the problem.

Academically the thesis provides nourishment to the 'relational turn' in the social sciences. This turn emerges from the acknowledgement that our societies and their global connectivity created an intensely complex situation that we struggle to theorize about with the current approaches in the social sciences.
Its benefit to society lies in reacting to the fact that global crises will be threatening our societies more and more often. Academics and especially policy-makers need to have new strategies to deal with this new reality which is precisely where this thesis can help.

Supervisor is Professor Peeter Selg from Tallinn University. Opponents are Associate Professor Scott Eacott from the University of New South Wales and Associate Professor Olli Pyyhtinen from the University of Tampere.

The doctoral thesis is available in Tallinn University Digital Library ETERA. https://www.etera.ee/zoom/145151/view?page=1&p=separate&search=Anna-Maria%20Rebane&tool=search&view=0,0,2067,2835

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PROTESTANTISM

Believing leisure is wasteful reduces happiness

Researchers find the benefits of free time depend on our beliefs about it


Peer-Reviewed Publication

RUTGERS UNIVERSITY

While many – from Aristotle to the Dalai Lama – have opined on the state of human happiness, a new Rutgers-led study finds that utter contentment depends, at least in part, on believing that leisure activities are not a waste of time.

The findings from four studies appear in the Journal of Experimental Social Psychology

“While work can impart meaning and a sense of purpose in life, leisure, such as time with family and friends, hobbies and exercise, is what makes our lives happy and healthy,” said lead author Gabriela Tonietto, an assistant professor of marketing at Rutgers Business School–Newark and New Brunswick. “But not everyone sees value in time spent on leisure. Many hold a general belief that these activities are an unproductive use of time – at the cost of their own happiness. We find that believing leisure is wasteful causes time spent on leisure to be less enjoyable.”

According to the study, thinking of leisure as wasteful prevents us from enjoying our leisure pursuits – especially purely pleasure activities such as hanging out with friends, watching TV and just relaxing.

More goal-oriented leisure activities, like exercise and meditation, tend to feel productive and so are still enjoyed whether or not people see value in their leisure.

The results show that those who do not enjoy pleasure-driven activities are more depressed, anxious and stressed. The findings suggest happiness may be driven not only by whether people engage in leisure, but whether they find value in what they are doing.

In one part of the study, the researchers asked 302 people to recall what they did for Halloween, how much they enjoyed the holiday and their attitudes toward leisure in general. Those who believe leisure is wasteful enjoyed their Halloween less, especially when they engaged in activities like going to a party compared to other activities that might be fun but might also fulfill responsibilities, like trick or treating with their kids. 

In another part of the study, participants read a news article meant to convince the reader that leisure is wasteful, unproductive or productive.

Next they watched the “Best Funny Cat Videos 2019” and were asked how much they enjoyed it. Those who believed that leisure is wasteful or unproductive didn’t enjoy watching the video as much as those who thought leisure time was productive and important.

The researchers suggest that people who think leisure is wasteful relate it to instances where it is used to procrastinate at the expense of work or necessary tasks. Sometimes, reseachers say, leisure is used to waste time, but most of the time, leisure is valuable.

“Attitudes can be difficult to change, so it may not be possible to shift beliefs about leisure overnight,” said Tonietto. “For those who think of leisure as wasteful, focusing on the productive ways that individual leisure activities can serve their long-term goals can help.”

The research was conducted in collaboration with researchers from The Ohio State University and Harvard University.

#LEGALISEDRUGS

NIH-funded study finds overall rate of drug use among 10-14 year-olds remained stable during the 2020 COVID-19 pandemic


Adolescents experiencing stress, mental health issues, and hardship most likely to use substances

Peer-Reviewed Publication

NIH/NATIONAL INSTITUTE ON DRUG ABUSE

Repeated surveys of more than 7,800 people ages 10 to 14 conducted between September 2019 and August 2020 showed that the overall rate of drug use among these young adolescents remained relatively stable before and during the first six months of the COVID-19 pandemic. However, researchers detected shifts in the drugs used, with alcohol use declining and use of nicotine products and misuse of prescription medications increasing. Adolescents who experienced pandemic-related severe stress, depression, or anxiety, or whose families experienced material hardship during the pandemic, were most likely to use substances.

The study, which published today in the Journal of Adolescent Health, was funded by the National Institute on Drug Abuse (NIDA) and nine other institutes, centers, and offices that are part of the National Institutes of Health. The analysis used data from the ongoing Adolescent Brain Cognitive DevelopmentSM (ABCD) Study, the largest long-term study of brain development and child health ever conducted in the United States. 

“The past year has been difficult, and adolescents have experienced a year of turmoil and stress in precarious space between childhood and adulthood. Recognizing how the stress of the past year translates into substance use has profound implications into adulthood, because drinking and drug use at these ages are associated with a substantially higher risk of long-term alcohol and drug use disorders and related harms,” said NIDA Director Nora D. Volkow, M.D. “Because the ABCD Study had already been following this diverse, young population, researchers were able to make direct comparisons between trends in substance use before and during the pandemic, emphasizing the value of investing in long-term, collaborative research projects.”

Several studies previously determined that older adolescents’ substance use held steady or even declined during the pandemic. However, most of these analyses were done earlier in the pandemic, and no data existed on the pandemic’s influence on younger adolescents, particularly after an extended period of COVID-19–related disruptions of daily lives.

To fill this gap, the research team conducted three surveys in the six months following the initiation of stay-at-home orders—in May, June, and August 2020—with more than 7,800 ABCD Study participants ages 10 to 14 and their families participating in at least one survey. They assessed the adolescents’ use of alcohol, nicotine products, cannabis, and other drugs, misuse of prescription drugs, as well as numerous general and pandemic-related factors that could influence substance use.

The study found that overall substance use in this age group remained relatively stable across the three surveys and occurred infrequently. Across all three surveys, 8% of the adolescents reported any substance use in the past 30 days. Alcohol and nicotine use were most common (3.4% and 3.6% of the adolescents, respectively), whereas rates of misuse of prescription drugs and use of cannabis, inhalants, or other drugs were low (1.1% of adolescents or less). Most youth reported using only one substance and only on one to two days per month.

The researchers also found that youth stress, anxiety, and depressive symptoms were all positively associated with the use of any substance, and that several pandemic-related factors increased adolescents’ likelihood of substance use. For example, youth who reported feeling “extreme” stress from the uncertainty associated with the pandemic were 2.4 times more likely to use any substance than youth who reported “very slight” stress.

For a subset of 1,079 participants, researchers were able to link assessments taken after the onset of the COVID-19 pandemic to assessments that had been completed during the months immediately before the pandemic. Importantly, for this subsample of youth, the overall rate of drug use did not increase significantly after the beginning of the pandemic compared to before the pandemic.

However, shifts occurred in the types of substances used. Alcohol use decreased, shifting from 1.9% of youth reporting alcohol use in the past 30 days in the surveys taken before the pandemic, to only 0.7% in the first survey during the pandemic. Conversely, nicotine use and prescription drug misuse increased, with 0% of youth reporting use of nicotine or misuse of prescription drugs in the past 30 days in the surveys taken before the pandemic, compared to 1.5% and 0.7% respectively in the first survey during the pandemic.

“These data suggest substance use during the pandemic was concentrated among youth from the most vulnerable families, underscoring the need to provide support to those young people and their families,” said William E. Pelham, Ph.D., of the University of California, San Diego, who led the study. “But we should also look forward, beyond the 2020 data, to understand how alcohol and drug use will continue to evolve as people return to school and work. By continuing to follow these young people for five or six more years through the ABCD Study, we can help determine the pandemic’s full impact on America’s youth and care for their health and wellbeing.”

The authors note that the study does not directly test or explain why the changes in the drugs used occurred, and additional analyses are needed to determine the mechanisms underlying these trends. Earlier findings from a different study reported steady rates of substance use in older adolescents. Continued research to understand substance use trends during and following the outset of the COVID-19 pandemic are needed for all age groups and across demographics.

Reference: WE Pelham III, SF Tapert, MR Gonzalez, et al. Early adolescent substance use before and during the COVID-19 pandemic: A longitudinal survey in the ABCD Study cohortJournal of Adolescent Health. DOI: 10.1016/j.jadohealth.2021.06.015 (2021).

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About the National Institute on Drug Abuse (NIDA): NIDA is a component of the National Institutes of Health, U.S. Department of Health and Human Services. NIDA supports most of the world’s research on the health aspects of drug use and addiction. The Institute carries out a large variety of programs to inform policy, improve practice, and advance addiction science. For more information about NIDA and its programs, visit www.nida.nih.gov.

About the National Institutes of Health (NIH): NIH, the nation’s medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.

NIH…Turning Discovery Into Health®

Stress from rising population numbers may cause a decline in human fertility

Peer-Reviewed Publication

THE ENDOCRINE SOCIETY

WASHINGTON—A predicted population drop at the end of the century could be explained by stress from meaningless social interactions, according to a review article published in the Endocrine Society’s journal, Endocrinology.

Researchers predict a peak in population numbers in 2064 followed by a 50% drop by the end of the century from changes in human reproductive behavior and function. There has been a 50% decrease in sperm counts over the last 50 years. People are stressed out from more frequent but less quality social interactions, and stress can supress sperm count, ovulation and sexual activity.

"Rising population numbers contribute to less meaningful social interactions, social withdrawal and chronic stress, which subsequently supresses reproduction,” said the manuscript’s author Alexander Suvorov, Ph.D., of the University of Massachusetts Amherst in Amherst, Mass. “Changes in reproductive behavior that contribute to the population drop include more young couples choosing to be ‘child-free,’ people having fewer children and couples waiting longer to start families.”

Suvorov found a connection between population numbers, stress and reproduction by reviewing several studies and asking the following questions:  

  • Why do people refuse to have children when access to all vital resources is becoming better than humankind ever had?

  • Why has there been a 50% decrease in sperm counts over the last 50 years?  

  • Why are different forms of social withdrawal on rise?  

He hypothesized declining reproduction may be due to stress from less quality social interactions and changes in reproductive behavior such an increase in “child-free” couples and delayed parenthood.

“Numerous wildlife and laboratory studies demonstrated that population peaks are always followed by increased stress and suppressed reproduction,” said Suvorov. “This review provides evidence from multiple disciplines that the same mechanisms previously observed in wildlife species may work in humans as well.”

The manuscript received no external funding.

The manuscript, Population Numbers and Reproductive Health,” was published online, ahead of print.

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Endocrinologists are at the core of solving the most pressing health problems of our time, from diabetes and obesity to infertility, bone health, and hormone-related cancers. The Endocrine Society is the world’s oldest and largest organization of scientists devoted to hormone research and physicians who care for people with hormone-related conditions.

The Society has more than 18,000 members, including scientists, physicians, educators, nurses and students in 122 countries. To learn more about the Society and the field of endocrinology, visit our site at www.endocrine.org. Follow us on Twitter at @TheEndoSociety and @EndoMedia