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Showing posts sorted by date for query WOMENS MARCH. Sort by relevance Show all posts

Saturday, March 06, 2021

THE ORIGINAL BIRTH CONTROL

One size doesn't fit all when it comes to products for preventing HIV from anal sex

MICROBICIDE TRIALS NETWORK

Research News

The initial insights from the study, aptly named DESIRE (Developing and Evaluating Short-acting Innovations for Rectal Use), are being reported on March 6 in a Science Spotlight session at the virtual meeting of the Conference on Retroviruses and Opportunistic Infections (CROI), March 6-10. The presentation will be available for registered participants and media to view throughout the meeting.

Conducted by the National Institutes of Health (NIH)-funded Microbicide Trials Network (MTN), DESIRE focused on potential delivery methods for rectal microbicides - topical products being developed and tested to reduce a person's risk of acquiring HIV and other sexually transmitted infections from anal sex. MTN researchers are particularly interested in on-demand options - used around the time of sex - and behaviorally congruent options that deliver anti-HIV drugs via products people may already be using as part of their sex routine.

"DESIRE stands out as a unique study because we took a step back and said, 'Let's figure out the modality without automatically pairing it with a drug'," explained José A. Bauermeister, Ph.D., M.P.H., study protocol chair and Albert M. Greenfield Professor of Human Relations at the University of Pennsylvania. "It gave us the ability to manipulate the delivery method without having to worry about how reactions to a particular drug might confound the results. We also had people trying out these methods in their own lives, and only then asked them to weigh the attributes of each." As such, he said, participants weren't making choices based on theoretical concepts, but instead using real experiences to guide their preferences.

Launched in 2019, DESIRE, also referred to as MTN-035, is the first study to explore multiple placebo methods for delivering a rectal microbicide. The three delivery methods assessed included a fast-dissolving placebo insert approximately two-thirds of an inch in length, a placebo suppository approximately an inch and a half in length, and a commercially available 120 mL douche bottle that participants were instructed to fill with clean tap or bottled water prior to use.

The study enrolled 217 participants who used each rectal delivery method for a month at a time, with a week-long break in between. Study participants, whose average age was 25 years, included cisgender men who have sex with men (79 percent) as well as transgender women (19 percent) and transgender men (2 percent) who have sex with men. The participants, based in Malawi, Peru, South Africa, Thailand and the United States (Birmingham, Pittsburgh and San Francisco), were instructed to use each method between 30 minutes and 3 hours prior to engaging in receptive anal sex, or once a week if they had not engaged in receptive anal sex in a given week.

To evaluate the acceptability of each method, participants were asked to complete a four-item survey once a week by text, commonly referred to as short message service (SMS), in their preferred language. After a month of using a particular delivery method, they were asked to complete a computer-assisted interview, with a subset of participants also completing an in-depth interview led by one of the study researchers.

At their final study visit, participants ranked attributes of a hypothetical product for preventing HIV from anal sex, and researchers used conjoint analysis - a market research approach that measures the value consumers place on features of a product or service - to calculate the percentage of weight participants gave to each attribute. They found that efficacy was the strongest determinant of participants' stated modality choice at 30 percent, followed by delivery method (18 percent) and side effects (17 percent). Other factors - timing of use before sex, duration of protection, frequency of use, and the need for a prescription - were not weighted as having as much importance by study participants. Through further analysis, researchers identified the participants' most preferred package based on the product features: A douche used 30 minutes before sex with 95 percent efficacy that offers three to five days of protection. This ideal product would also only need to be used once a week, have no side effects, and be available over the counter.

While this market research approach offered insights into the most common package of features, participants also underscored how each of the modalities could offer unique advantages in their daily lives.

"As you might expect, the context of the participants' lives informed their product choice," said Dr. Bauermeister. "When asked to rank the most preferred product attributes, they based their answers on their own experiences and the tradeoffs they might make in real-life situations." In some instances, he explained, discretion might be important, so a small tablet in the form of a fast-dissolving rectal insert that could be carried in your pocket might be the best option. At other times, hygiene may be a priority and a douche would be preferred. As a pre-lubricated product, even the suppository had unexpected advantages with some participants commenting about it's potential as an alternative to sexual lubricant.

"The lesson we learned from MTN-035 is that even though the douche was preferred overall, we shouldn't assume it's right for everyone every time they plan to have sex," said Dr. Bauermeister. "Depending on who you are, what you do and where you live, it may not be a viable, or even a desirable, option for HIV prevention. At the end of the day, people could see all three of these modalities fitting into their lives."

Researchers like Dr. Bauermeister are hopeful these results will inform the development of rectal microbicides moving forward, and lead to expanded choices in preventing HIV from anal sex.

###

MTN-035 was conducted at the following clinical research sites (CRSs): the College of Medicine-Johns Hopkins Research Project in Blantyre, Malawi; the IMPACTA CRS in Lima, Peru; the Wits Reproductive Health and HIV Institute in Johannesburg, South Africa; the Chiang Mai University HIV Prevention CRS in Thailand; and, in the United States, the University of Pittsburgh CRS, Bridge HIV CRS in San Francisco, and University of Alabama at Birmingham CRS.

The MTN is funded by the National Institute of Allergy and Infectious Diseases (NIAID), the Eunice Kennedy Shriver National Institute of Child Health and Human Development and the National Institute of Mental Health, all part of the NIH. The placebo rectal insert used in the study was developed by CONRAD, a not-for-profit research and development organization based at Eastern Virginia Medical School in Norfolk, Va.

Dr. Bauermeister's presentation "Developing and Evaluating Short-Acting Innovations for Rectal Use (Desire): Acceptability and choice for three placebo products used with receptive anal intercourse among young MSM and TG people" will be viewable beginning at 12:01 a.m. (EST), Saturday, March 6. Please visit http://www.croiconference.org for more information.

The MTN is funded by the U.S. National Institutes of Health grants UM1AI068633, UM1AI068615, UM1AI106707. CONRAD's support for MTN-035 and provision of the placebo insert is made possible by the generous support of the American people through a Cooperative Agreement (AID-OAA-A-14-00010) with the U.S. Agency for International Development/U.S. President's Emergency Plan for AIDS Relief.

About the Microbicide Trials Network

The Microbicide Trials Network (MTN) is an HIV/AIDS clinical trials network established in 2006 by the National Institute of Allergy and Infectious Diseases with co-funding from the Eunice Kennedy Shriver National Institute of Child Health and Human Development and the National Institute of Mental Health, all components of the U.S. National Institutes of Health. Based at Magee-Womens Research Institute and the University of Pittsburgh, the MTN brings together international investigators and community and industry partners whose work is focused on the rigorous evaluation of promising microbicides - products applied inside the vagina or rectum that are intended to prevent the sexual transmission of HIV - from the earliest phases of clinical study to large-scale trials that support potential licensure of these products for widespread use. More information about the MTN is available at https://mtnstopshiv.org.

Tuesday, January 19, 2021


During lockdowns, women took on most of burden of childcare

#WAGESFORHOUSEWORK #UBI POSTPANDEMIC ECONOMICS


HEALTH NEWS
JAN. 18, 2021 / 11:50 AM


Thirty-seven percent of couples surveyed relied on the wife to provide most or all childcare, 44.5% used more egalitarian strategies and nearly 19% used strategies that were not gendered or egalitarian. File Photo by John Angelillo/UPI | License Photo



Despite being locked down during the pandemic, childcare responsibilities often fell on women's shoulders, a new study shows.

"Most people have never undergone anything like this before, where all of a sudden they can't rely on their normal childcare, and most people's work situation has changed, too," said researcher Kristen Shockley, an associate professor of psychology at the University of Georgia. "We thought this would be a chance for men to step in and partake equally in childcare, but for many couples we didn't see that happen."

In mid-March, as schools and day care centers shut down, Shockley's team surveyed couples, both of whom worked and had at least one child under the age of 6. The team researchers first surveyed 274 couples and followed up with 133 of the same couples in May.

"When the wife does it all, not surprisingly, the outcomes are bad for the couple," Shockley said in a university news release. "It's not just bad for the wife, it's also bad for the husband, including in terms of job performance although his work role presumably hasn't changed. When one person's doing it all, there's a lot of tension in the relationship, and it's probably spilling over into the husband's ability to focus at work."

Although about 37% of couples relied on the wife to provide most or all childcare, 44.5% used more egalitarian strategies and nearly 19% used strategies that were not gendered or egalitarian.

Co-parenting strategies included alternating workdays, planning daily shifts that included both work and childcare for husband and wife, and alternating schedules that changed based on the couple's work needs. These strategies actually increased the productivity of both parents.

"When you look at the more egalitarian strategies, we found the best outcomes for people who were able to alternate working days," Shockley said. "The boundaries are clear. When you're working, you can really focus on work, and when you're taking care of the kids, you can really focus on the kids. But not everybody has jobs amenable to that."

The paper doesn't include qualitative quotes, but Shockley clearly remembers the participants' comments.


"People were saying, 'I'm at my breaking point,' and this was just two weeks in. A lot of people said, 'I'm just not sleeping.' You could feel people's struggle, and there was a lot of resentment, particularly when the wife was doing it all," she said.

"This really highlights some infrastructure issues we have with the way we think about child care in this country," Shockley said. "The default becomes, 'Oh well, the wife is going to pick up the slack.' It's not a long-term solution."

Shockley noted that the couples surveyed had relatively high incomes.

The report was published in the January issue of the Journal of Applied Psychology.More information

For more on coping during the pandemic, see the U.S. Centers for Disease Control and Prevention.

Copyright 2020 HealthDay. All rights reserved.

  • The History of the Wages for Housework Campaign - Louise ...

    https://www.plutobooks.com/blog/wages-housework-campaign-history

    The Wages for Housework perspective was a completely original school of thought, and a toolbox for action, at the beginning of second-wave feminism. It was accused of being a simple demand for money, partial and reformist – even reactionary – that went counter to the objective of women’s equality in society. But it was much more than that.

  • Wages for housework - Wikipedia

    https://en.wikipedia.org/wiki/Wages_for_housework

    The International Wages for Housework Campaign (IWFHC) is a grassroots women's network campaigning for recognition and payment for all caring work, in the home and outside. It was started in 1972 by Selma James who first put forward the demand for wages for housework at the third National Women's Liberation Conferencein Manchester, England. The IWFHC state that they begin with those with least power internationally – unwaged workers in the home (mothers, housewives, domestic workers de…

    Wikipedia · Text under CC-BY-SA license
  • WAGES FOR HOUSEWORK CAMPAIGN

    https://www.freedomarchives.org/.../500.020.Wages.for.Housework.p… · PDF file

    INTERNATIONAL WAGES FOR HOUSEWORK CAMPAIGN Since 1972, the International Wages for Housework Campaign (IWFHC), a net­ work of Third World and metropolitan women, has been organizing to get rec­ ognition and compensation by govern­ ments for the unwaged work women do in the home, on the land and in the com­ munity, to be paid by dismantling the

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    • Page Count: 2
  • Wages for Housework Campaign Bulletin – Rise Up! Feminist ...

    https://riseupfeministarchive.ca/.../wages-for-housework-campaign-bulletin

    The Wages for Housework Campaign Bulletin was a publication of the Toronto Wages for Housework Committee. The International Wages for Housework Campaign was co-founded in 1972 by Selma James, Mariarosa Dalla Costa, Silvia Federici, and Brigitte Galtier, and was organized around the principle that women should be paid for performing the socially necessary labour of housework and childcare.

  • I founded the Wages for Housework campaign in 1972 – and ...

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    2020-03-10 · Selma James is founder of the Wages for Housework campaign which coordinates the Global Women’s Strike, based at the Crossroads Women’s Centre. WS and other organisations based at …

  • Wages For Housework | New Internationalist

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    1988-03-05 · Yet the Wages for Housework campaigners remain vociferous, as do their opponents. Wages for Housework is more than a single demand; it offers a controversial perspective on a wide range of feminist concerns, and the politics and economics of housework have been debated in the context of Greenham Common, campaigns for the rights of prostitutes, campaigns against racismcampaigns against rape.

  • Silvia Federici reflects on Wages for Housework : New Frame

    https://www.newframe.com/silvia-federici-reflects-wages-housework

    18 Oct 2018. Features. 'The goal was to get wages for housework in order to raise the level of our struggle, not to end it,' says Silvia Federici. (Photograph by Luis Nieto Dickens) In 1972, Silvia Federici participated in founding the Wages for Housework campaign of the International Feminist Collective, which formed chapters in Italy, the United Kingdom and the United States to demand wages from their …

  • The Women of Wages for Housework | The Nation

    https://www.thenation.com/article/archive/wages-for-houseworks-radical-vision

    2018-03-14 · From the gathering in Padua, Italy, that launched the international campaign in 1972 to the spin-off groups like the New York Committee, the women of Wages for Housework 






  • Thursday, December 03, 2020

    'I WILL TALK TO JOE ABOUT IT'
    Barack Obama reveals it was a 'mistake' to not give Dolly Parton the Presidential Medal of Freedom

    By BRIAN GALLAGHER FOR DAILYMAIL.COM

    PUBLISHED: 2 December 2020

    Barack Obama handed out 123 Presidential Medals of Freedom during his eight-year tenure as President, though he admitted it was a 'mistake' to not give one to Dolly Parton.

    Parton, 74, made headlines last month when it was revealed that her $1 million donation helped fund the research that ultimately lead to Moderna's vaccine.

    While Obama's 123 Presidental Medals of Freedom is the most ever handed out since the award was established in 1963, Obama admitted on A Late Show With Stephen Colbert that he should have given her one. 


    Mistake: Barack Obama handed out 123 Presidential Medals of Freedom during his eight-year tenure as President, though he admitted it was a 'mistake' to not give one to Dolly Parton


    Donation: Parton, 74, made headlines last month when it was revealed that her $1 million donation helped fund the research that ultimately lead to Moderna's vaccine

    Obama, 59, took part in a recurring segment of Colbert's, where he asks his guests questions he doesn't think they've ever been asked before.

    When Colbert asked Obama, 'How does Dolly Parton not have a Presidential Medal of Freedom,' the former President seemed taken aback.


    'That was a mistake. I'm shocked,' Obama said, when Colbert began to joke, 'Looking back on the eight years, do you realize that's the mistake you made?'

    Segment: Obama, 59, took part in a recurring segment of Colbert's, where he asks his guests questions he doesn't think they've ever been asked before


    Taken aback: When Colbert asked Obama, 'How does Dolly Parton not have a Presidential Medal of Freedom,' the former President seemed taken aback

    Obama added, 'Actually, that was a screw-up. I'm surprised. I think I assumed that she had already got one, and that was incorrect.'

    He added that, 'she deserves one. I'll call Biden,' referring to President-Elect Joe Biden, his former Vice President.

    It's possible Parton could be one of Biden's first Presidential Medal of Freedom recipients when he takes office in 2021.

    Screw-up: Obama added, 'Actually, that was a screw-up. I'm surprised. I think I assumed that she had already got one, and that was incorrect.

    Calling Biden: He added that, 'she deserves one. I'll call Biden,' referring to President-Elect Joe Biden, his former Vice President

    The Presidential Medal of Freedom was first established by President John F. Kennedy in 1963.

    The medal is awarded to those who have provided an, 'especially meritorious contribution to the security or national interests of the United States, world peace, cultural or other significant public or private endeavors.'

    The Presidential Medal of Freedom is one of the highest awards given to civilians of the United States, along with the Congressional Gold Medal.

    Medal: The Presidential Medal of Freedom was first established by President John F. Kennedy in 1963

    Parton donated $1 million to Vanderbilt University back in April, just weeks after COVID-19 was officially declared a worldwide pandemic.

    Those funds helped contribute to Moderna's vaccine, which has reported to be upwards of 94.5% effective in combating COVID-19.

    The country singer revealed in an interview she was, 'a very proud girl today to know I had anything at all to do with something that's going to help us through this crazy pandemic.'

    Donation: Parton donated $1 million to Vanderbilt University back in April, just weeks after COVID-19 was officially declared a worldwide pandemic

    Vaccine: Those funds helped contribute to Moderna's vaccine, which has reported to be upwards of 94.5% effective in combating COVID-19

    Proud: The country singer revealed in an interview she was, 'a very proud girl today to know I had anything at all to do with something that's going to help us through this crazy pandemic'





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