Friday, May 29, 2020


Hydropower plants to support solar and wind energy in West Africa

KU LEUVEN


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IMAGE: SOLAR STREET LIGHTING IN NIGER. view more 
CREDIT: SEBASTIAN STERL

Hydropower plants can support solar and wind power, rather unpredictable by nature, in a climate-friendly manner. A new study in the scientific journal Nature Sustainability has now mapped the potential for such "solar-wind-water" strategies for West Africa: an important region where the power sector is still under development, and where generation capacity and power grids will be greatly expanded in the coming years. "Countries in West Africa therefore now have the opportunity to plan this expansion according to strategies that rely on modern, climate-friendly energy generation," says Sebastian Sterl, energy and climate scientist at Vrije Universiteit Brussel and KU Leuven and lead author of the study. "A completely different situation from Europe, where power supply has been dependent on polluting power plants for many decades - which many countries now want to rid themselves of."
Solar and wind power generation is increasing worldwide and becoming cheaper and cheaper. This helps to keep climate targets in sight, but also poses challenges. For instance, critics often argue that these energy sources are too unpredictable and variable to be part of a reliable electricity mix on a large scale.
"Indeed, our electricity systems will have to become much more flexible if we are to feed large amounts of solar and wind power into the grid. Flexibility is currently mostly provided by gas power plants. Unfortunately, these cause a lot of CO2 emissions," says Sebastian Sterl, energy and climate expert at Vrije Universiteit Brussel (VUB) and KU Leuven. "But in many countries, hydropower plants can be a fossil fuel-free alternative to support solar and wind energy. After all, hydropower plants can be dispatched at times when insufficient solar and wind power is available."


Hydropower plant in Gui, Ghana.
The research team, composed of experts from VUB, KU Leuven, the International Renewable Energy Agency (IRENA), and Climate Analytics, designed a new computer model for their study, running on detailed water, weather and climate data. They used this model to investigate how renewable power sources in West Africa could be exploited as effectively as possible for a reliable power supply, even without large-scale storage. All this without losing sight of the environmental impact of large hydropower plants.
"This is far from trivial to calculate," says Prof. Wim Thiery, climate scientist at the VUB, who was also involved in the study. "Hydroelectric power stations in West Africa depend on the monsoon; in the dry season they run on their reserves. Both sun and wind, as well as power requirements, have their own typical hourly, daily and seasonal patterns. Solar, wind and hydropower all vary from year to year and may be impacted by climate change. In addition, their potential is spatially very unevenly distributed."

West African Power Pool

The study demonstrates that it will be particularly important to create a "West African Power Pool", a regional interconnection of national power grids. Countries with a tropical climate, such as Ghana and the Ivory Coast, typically have a lot of potential for hydropower and quite high solar radiation, but hardly any wind. The drier and more desert-like countries, such as Senegal and Niger, hardly have any opportunities for hydropower, but receive more sunlight and more wind. The potential for reliable, clean power generation based on solar and wind power, supported by flexibly dispatched hydropower, increases by more than 30% when countries can share their potential regionally, the researchers discovered.
All measures taken together would allow roughly 60% of the current electricity demand in West Africa to be met with complementary renewable sources, of which roughly half would be solar and wind power and the other half hydropower - without the need for large-scale battery or other storage plants. According to the study, within a few years, the cost of solar and wind power generation in West Africa is also expected to drop to such an extent that the proposed solar-wind-water strategies will provide cheaper electricity than gas-fired power plants, which currently still account for more than half of all electricity supply in West Africa.

Better ecological footprint

Hydropower plants can have a considerable negative impact on local ecology. In many developing countries, piles of controversial plans for new hydropower plants have been proposed. The study can help to make future investments in hydropower more sustainable. "By using existing and planned hydropower plants as optimally as possible to massively support solar and wind energy, one can at the same time make certain new dams superfluous," says Sterl. "This way two birds can be caught with one stone. Simultaneously, one avoids CO2 emissions from gas-fired power stations and the environmental impact of hydropower overexploitation."

Left: current policy plans Right: West African Power Pool scenario

Global relevance

The methods developed for the study are easily transferable to other regions, and the research has worldwide relevance. Sterl: "Nearly all regions with a lot of hydropower, or hydropower potential, could use it to compensate shortfalls in solar and wind power." Various European countries, with Norway at the front, have shown increased interest in recent years to deploy their hydropower to support solar and wind power in EU countries. Exporting Norwegian hydropower during times when other countries undergo solar and wind power shortfalls, the European energy transition can be advanced.
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Changes in cropping methods, climate, decoy pintail ducks into an ecological trap

Important waterfowl species struggling with conditions in the Prairie Pothole Region
PENN STATE NEWS RELEASE 




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IMAGE: PINTAILS ARE NOT THRIVING LIKE OTHER SPECIES OF DABBLING DUCKS, AND RESEARCHERS THINK THAT'S BECAUSE THEY ARE BEING 'MISLED' BY MODERN CROPPING METHODS AND CLIMATE CHANGE INTO CHOOSING RISKY NESTING... view more 
CREDIT: F. GREENSLADE-DELTA WATERFOWL

After a severe drought gripped the Prairie Pothole Region of the U.S. and Canada in the 1980s, populations of almost all dabbling duck species that breed there have recovered. But not northern pintails. Now, a new study by a team of researchers suggests why -- they have been caught in an ecological trap.
The Prairie Pothole region straddles the U.S.-Canada border and sprawls from central Iowa in the south to Alberta in the north, covering a large swath of Minnesota, South Dakota, North Dakota, Manitoba and Saskatchewan in between.
"With increasing cropland cover in the region, pintails have been selecting for cropland over scarce alternative nesting habitat, probably because it is similar to the native mixed-grass prairie they evolved to nest in," said lead researcher Frances Buderman, Penn State. "That behavior results in fewer pintails the following year due to nest failures from predation and agricultural practices."
The U.S. Fish and Wildlife Service's North American Waterfowl Management Plan calls for more than 4 million pintails, but recent estimates are only half of that. The reason pintails are not thriving like other dabbling ducks, according to Buderman, assistant professor of quantitative wildlife ecology in the College of Agricultural Sciences, is that they are being "misled" by modern cropping methods and climate change into choosing risky nesting habitat.
Also called puddle ducks, dabbling ducks frequent shallow waters such as flooded fields and marshes. They feed by tipping up rather than diving. There are 38 species of dabbling ducks -- they float high in the water and are swift fliers.
By their very nature, pintails may be vulnerable to the ecological trap, Buderman explained. Despite being an early-spring nester -- a quality that typically would allow for reproductive "plasticity" to climatic conditions -- pintails have demonstrated inflexible breeding behavior, such as being unwilling or unable to delay nest initiation and being less likely to renest than most other waterfowl.
"Inflexible breeding behavior may result in greater vulnerability to unpredictable weather events and changes in climactic conditions," she said. And given their preference for nesting among landscapes of grass-like, low-lying cover, pintails readily nest in fields of stubble in untilled agricultural fields. "Unlike other ducks that generally avoid nesting in stubble, pintails in the Prairie Pothole Region commonly select crop stubble nest sites and often select it over remnant patches of grass and other cover."
Pintails often initiate nests before remaining stubble fields are worked by farmers in the spring, making nests vulnerable to mechanical spring tilling and planting of remaining standing stubble, Buderman explained. That can destroy a large percentage of initial nests. Exacerbating the effect of pintail selections over time, the amount of land in the Prairie Pothole Region annually tilled for spring-seeded crops has increased by approximately 34% since 1959.


For reasons not clearly understood by wildlife scientists, pintails appear to be particularly sensitive to changes in the number of productive, small wetlands that have occurred across the Prairie Pothole Region.

Dabbling duck incoming
Another factor that is contributing to pintails' decline, researchers contend, is a trend in some areas of the Prairie Pothole Region to manipulate drainage to consolidate surface water into larger and deeper wetlands that dry out less frequently and have more surface-water connections to other wetlands.
Those drainage practices make mowing around ponds easier for farmers, and most waterfowl species have coped thus far, but it hasn't been good for pintails. Wildlife scientists suspect the birds need the smaller, shallower, ephemeral ponds with which they evolved. For reasons not clearly understood, pintails appear to be particularly sensitive to changes in the number of productive, small wetlands that have occurred across the Prairie Pothole Region.
Buderman pointed out that funding partner Delta Waterfowl is working hard to restore these valuable seasonal wetlands on the U.S. side of the region by establishing a Working Wetlands program in the U.S. Department of Agriculture via the federal farm bill.
To reach their conclusions, researchers used more than 60 years of data from the U.S. Fish and Wildlife Service and the Canadian Wildlife Service, which have monitored spring population sizes for North American waterfowl since 1955. They published their results in the Journal of Animal Ecology,
That information is organized into regions that reflect both habitat differences and political boundaries. For many decades, waterfowl have been counted on both sides of the border by aerial crews flying fixed-wing aircraft along established transect lines at low altitude, while simultaneously, ground counts are conducted at ponds on a subset of air-surveyed areas.
To analyze population dynamics, researchers developed a complex model to deal with a huge dataset that took days to run on a powerful computer, which calculated a "breeding pintail count" for the survey period. The model -- which also took into account precipitation, climatic conditions during the breeding season and pond dynamics -- allowed researchers to identify the relative influence of long-term changes in climate and land use on both the selection and quality of habitat for pintails in the Prairie Pothole Region.

Pintails are one of 38 species of dabbling ducks, also known as puddle ducks. They frequent shallow waters such as flooded fields and marshes, and they feed by tipping up rather than diving. They float high in the water and are swift fliers.


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Also involved in the research were Jim Devries, Institute for Wetland and Waterfowl Research, Ducks Unlimited Canada, and David Koons, Department of Fish, Wildlife, and Conservation Biology, Colorado State University.
Delta Waterfowl, California Department of Water Resources and the James C. Kennedy Endowment for Wetland and Waterfowl Conservation at Colorado State University funded this research.

Survey identifies learning opportunities related to health impacts of climate change

COLUMBIA UNIVERSITY'S MAILMAN SCHOOL OF PUBLIC HEALTH
An international survey of Global Consortium on Climate and Health Education (GCCHE) membership found that the majority of members--health professions schools and programs, including medical, nursing, and public health--offer learning opportunities related to the health impacts of climate change, yet many also encountered challenges in instituting or developing curricula. The results of the survey provide a baseline assessment of the state of climate-health education internationally among health professions institutions. Results of the survey by Columbia University Mailman School of Public Health researchers appear in the journal JAMA Network Open.
The survey suggests there exist a range of educational offerings on climate-health, including sessions, courses, programs, or post-doctoral positions. Some schools have offered climate-health education for several years, some are just now adding content, and others do not include any content on the subject. While many schools are discussing adding climate-health educational offerings, there are still considerable gaps in offerings at many institutions as well as challenges that extend beyond the institutional level, such as political and funding priorities that might lead to lack of staff time and materials to support the training.
Conducted in 2017 and 2018, the survey was completed by 84 health professions institutions internationally. Among respondents, 63% offer climate-health education, most commonly as part of a required core course (76%). Sixty-one of 82 respondents (74%) reported additional climate-health offerings are under discussion, 42 of 59 (71%) encountered some challenges trying to institute the curriculum, and most have received a positive response to adding content mainly from students (39 of 58 (67%)), faculty (35 of 58 (60%)), and administration (23 of 58 (40%)).
The article's authors write that opportunities exist to facilitate the integration of climate-health curricula, such as working with students, faculty, and members of administration that are interested in this topic. In order to facilitate this integration, institutions can look to online resources, groups, and networks to provide guidance and information to develop curricula.
"We suggest that health professions schools include this content in their curricula and that awareness as well as financial support, resources, and expertise increase to help in its uptake," write study authors Brittany Shea, MA, Kim Knowlton, DrPH, and Jeffrey Shaman, PhD. "Climate change may be affecting health in a variety of ways with increasing consequences. Health professionals, including those in public health, nursing, and medical services, should be educated on how to prevent, mitigate, and respond to factors associated with climate change that may be associated with health in a negative way."
Brittany Shea is project director for GCCHE. Kim Knowlton is assistant professor of environmental health sciences and senior scientist with the Natural Resources Defense Council. Jeffrey Shaman directs GCCHE and the Columbia Mailman School Climate and Health Program; he is a professor of environmental health sciences.
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The study was made possible with financial support from The Rockefeller Foundation and ClimateWorks Foundation. Jeffrey Shaman and Columbia University disclosed partial ownership of SK Analytics. Shaman also disclosed providing paid consultant services for Merck and Business Network International.
About the Global Consortium on Climate and Health Education
The Global Consortium on Climate and Health Education (GCCHE) was launched in 2017 by faculty at Columbia University Mailman School of Public Health with the vision that all health professionals throughout the world will be trained to prevent, mitigate, and respond to the health impacts of climate change and other planetary changes that impact human health and well-being. To advance progress toward this goal, the GCCHE created a virtual town square across all health professions by bringing together member institutions to share best scientific and educational practices; develop global standards for knowledge and practice on the health impacts of climate change that all graduates of health professions schools should possess, as well as share resources that member institutions can use for this purpose; build a pipeline of health professionals who focus their work on the health impacts of climate change; and support the development of global academic partnerships to foster mutual learning, particularly in under-resourced countries. GCCHE currently includes over 200 member institutions in over 30 countries on six continents, representing institutions with over an estimated 150,000 students. The GCCHE has received financial support from several foundations, including The Rockefeller Foundation and ClimateWorks Foundation. Representatives of health professions schools are invited to join the GCCHE h

Smart sponge could clean up oil spills

Highly porous sponge selectively soaks up oil, sparing water and wildlife
NORTHWESTERN UNIVERSITY NEWS RELEASE 

EVANSTON, Ill. -- A Northwestern University-led team has developed a highly porous smart sponge that selectively soaks up oil in water.
With an ability to absorb more than 30 times its weight in oil, the sponge could be used to inexpensively and efficiently clean up oil spills without harming marine life. After squeezing the oil out of the sponge, it can be reused many dozens of times without losing its effectiveness.
"Oil spills have devastating and immediate effects on the environment, human health and economy," said Northwestern's Vinayak Dravid, who led the research. "Although many spills are small and may not make the evening news, they are still profoundly invasive to the ecosystem and surrounding community. Our sponge can remediate these spills in a more economic, efficient and eco-friendly manner than any of the current state-of-the-art solutions."
The research was published yesterday (May 27) in the journal Industrial Engineering and Chemical Research.
Dravid is the Abraham Harris Professor of Materials Science and Engineering at Northwestern's McCormick School of Engineering. Vikas Nandwana, a senior research associate in Dravid's laboratory, is the paper's first author.
Oil spill clean-up is an expensive and complicated process that often harms marine life and further damages the environment. Currently used solutions include burning the oil, using chemical dispersants to breakdown oil into very small droplets, skimming oil floating on top of water and/or absorbing it with expensive, unrecyclable sorbents.
"Each approach has its own drawbacks and none are sustainable solutions," Nandwana said. "Burning increases carbon emissions and dispersants are terribly harmful for marine wildlife. Skimmers don't work in rough waters or with thin layers of oil. And sorbents are not only expensive, but they generate a huge amount of physical waste -- similar to the diaper landfill issue."
The Northwestern solution bypasses these challenges by selectively absorbing oil and leaving clean water and unaffected marine life behind. The secret lies in a nanocomposite coating of magnetic nanostructures and a carbon-based substrate that is oleophilic (attracts oil), hydrophobic (resists water) and magnetic. The nanocomposite's nanoporous 3D structure selectively interacts with and binds to the oil molecules, capturing and storing the oil until it is squeezed out. The magnetic nanostructures give the smart sponge two additional functionalities: controlled movement in the presence of an external magnetic field and desorption of adsorbed components, such as oil, in a simulated and remote manner.
The OHM (oleophilic hydrophobic magnetic) nanocomposite slurry can be used to coat any cheap, commercially available sponge. The researchers applied a thin coating of the slurry to the sponge, squeezed out the excess and let it dry. The sponge is quickly and easily converted into a smart sponge (or "OHM sponge") with a selective affinity for oil.
Vinayak and his team tested the OHM sponge with many different types of crude oils of varying density and viscosity. The OHM sponge consistently absorbed up to 30 times its weight in oil, leaving the water behind. To mimic natural waves, researchers put the OHM sponge on a shaker submerged in water. Even after vigorous shaking, the sponge release less than 1% of its absorbed oil back into the water.
"Our sponge works effectively in diverse and extreme aquatic conditions that have different pH and salinity levels," Dravid said. "We believe we can address a giga-ton problem with a nanoscale solution."
"We are excited to introduce such smart sponges as an environmental remediation platform for selectively removing and recovering pollutants present in water, soil and air, such as excess nutrients, heavy metal contaminants, VOC/toxins and others," Nandwana said. "The nanostructure coating can be tailored to selectively adsorb (and later desorb) these pollutants."
The team also is working on another grade of OHM sponge that can selectively absorb (and later recover) excess dissolved nutrients, such as phosphates, from fertilizer runoff and agricultural pollution. Stephanie Ribet, a Ph.D. candidate in Dravid's lab and paper coauthor is pursuing this topic. The team plans to develop and commercialize OHM technology for environmental clean-up.

Smart sponge selectively absorbs oil (on the left) while resisting water (on the right).

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The research, "OHM Sponge: A versatile, efficient and eco-friendly environmental remediation platform," was supported by the National Science Foundation. Stephanie Ribet, Roberto Reis, Yuyao Kuang and Yash More -- all from Northwestern -- coauthored the paper.
Editor's note: Dravid, Nandwana and Northwestern will have financial interests (equities, royalties) if the technology is commercialized.

Reintroduction of wolves tied to return of tall willows in Yellowstone National Park

OREGON STATE UNIVERSITY
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IMAGE: IN YELLOWSTONE'S LAMAR VALLEY, BISON CONGREGATE IN THE SUMMER AND GRAZE NOT ONLY ON GRASS BUT ALSO ON WILLOW, COTTONWOOD, AND ASPEN. THESE BISON ARE EATING WILLOWS IN THE FOREGROUND,... view more 
CREDIT: LUKE PAINTER, OREGON STATE UNIVERSITY
CORVALLIS, Ore. - The reintroduction of wolves into Yellowstone National Park is tied to the recovery of tall willows in the park, according to a new Oregon State University-led study.
Wolves were reintroduced to the park in 1995. The new study shows their predation on elk is a major reason for an increase in the height of willows in northern Yellowstone, said Luke Painter, a wildlife ecologist at Oregon State University and lead author on the study.
There's been a debate among scientists over the degree to which willows may have recovered from decades of suppression by elk following the restoration of wolves and subsequent reductions in elk numbers, Painter said.
"Our results demonstrate that the reduction of elk browsing over the last two decades in northern Yellowstone has allowed willows to grow taller in many places, despite a warming and drying climate," Painter said, adding that willows aren't recovering in some areas due to continued browsing by increased numbers of bison.
Following wolf restoration in the 1990s, elk numbers decreased, and some researchers reported willows growing taller with reductions in elk browsing, evidence of a shift toward willow recovery.
The new study compared data from three time periods: 1988-1993, when elk densities were high and most willows very short; 2001-04, when willows may have begun to recover; and 2016-18.
The researchers confirmed that willows have indeed increased in height and cover in response to a reduction in browsing by elk.
The study is published in the journal Ecosphere.
Elk numbers in northern Yellowstone have declined from a high of nearly 20,000 in 1995 - the year wolves were restored to the park - to 4,149 counted over two days in March 2019 by biologists with Montana Fish, Wildlife, and Parks; U.S. Forest Service and U.S. Geological Survey.
Painter and co-author Michael Tercek of Walking Shadow Ecology in Montana found a strong contrast between sites along streams compared to wet meadows. Willows in meadow sites did not increase in height, but willows in stream sites increased significantly, exceeding 200 centimeters, or 6 feet - a height accessible to elk - in the summers of 2001-04 and in the spring of 2016.
They also found a significant change in willow thickets at least 200 centimeters in height along streams, with thickets occupying about 80% of willow patches in some sites, but as little as 22% in others. Tall willow thickets are an important habitat feature and an indicator of willow recovery, Painter said.
Thus, passive restoration through the return of predators has begun to reverse the loss of willows, something active culling of elk in the past was unable to accomplish, he said.
"Wolves didn't do it all by themselves," Painter said. "Other predators and hunters also affected elk, but this would not have happened without the wolves.
"This does not mean a wider expanse of willow habitat has been restored as existed in the early days of the park when beavers created large wetland expanses. This may eventually happen as beavers return but could take a long time to develop."
This is the latest OSU study led by Painter that examines the effects of wolf reintroduction to Yellowstone on trees. In 2018, he published a study that showed that aspen is recovering in areas around the park, as well as inside the park boundary.
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Painter teaches ecology and conservation in the OSU College of Agricultural Sciences and College of Forestry.


New Zealand blue whale distribution patterns tied to ocean conditions, prey availability

OREGON STATE UNIVERSITY


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IMAGE: A BLUE WHALE MOTHER-CALF PAIR SURFACES IN NEW ZEALAND'S SOUTH TARANAKI BIGHT. view more 
CREDIT: KRISTIN HODGE

NEWPORT, Ore. - Oregon State University researchers who recently discovered a population of blue whales in New Zealand are learning more about the links between the whales, their prey and ocean conditions that are changing as the planet warms.
Understanding how changes in climate affect the ability of blue whales to feed gives researchers more insight into the whales' overall health and provides critical information for conservation and management, said Leigh Torres, an assistant professor and director of the Geospatial Ecology of Marine Megafauna Laboratory at OSU's Marine Mammal Institute.
"These whales don't move around at random. We found that the same ocean patterns that determine where whales are also determine where their prey are, under both typical and warm ocean conditions," Torres said. "The more we learn about what drives these whales' movement, the more we can help protect them from whatever threats they face."
The researchers' findings were published today in the journal Marine Ecology Progress Series. The study's lead author is Dawn Barlow, a doctoral student in Torres' lab; additional co-authors are Kim Bernard of OSU's College of Earth, Ocean, and Atmospheric Sciences; Daniel Palacios of OSU's Marine Mammal Institute; and Pablo Escobar-Flores of the National Institute of Water and Atmospheric Sciences in New Zealand.
Torres, Barlow and colleagues recently documented this new population of New Zealand blue whales, which is genetically distinct from other blue whale populations and spends much of its time in the South Taranaki Bight between New Zealand's North and South Islands.
"The goal of our study is to understand the habitat use patterns of this population of blue whales - why they are where they are and how they respond to changing ocean conditions," Barlow said. "We know this area is important to this population of whales, and we want to understand what it is about this spot that is desirable to them."
The region is often rich in prey - blue whales feast on patches of krill - but the prey is patchy and influenced by changing ocean conditions, including warmer temperatures and changes in ocean properties. The South Taranaki Bight also sees frequent shipping traffic and activity from oil and gas exploration and production, Torres said.
Using data collected during typical summer conditions in 2014 and 2017 and warmer than average conditions in 2016, the researchers analyzed how changing ocean conditions affect the blue whales' distribution in the region's waters and the availability and location of their prey within the water column.
They found that during a regional marine heat wave in 2016, there were fewer aggregations of krill for the whales to dine on. With fewer options, the whales pursued the densest aggregations of krill they could find, Barlow said.


The researchers also found that during both warm and more typical ocean conditions the whales were more likely to feed in areas where the water was cooler. During the marine heat wave, when even the coolest water temperatures were higher than normal conditions, the whales still sought the coolest waters available for feeding.
In this region, cooler water temperatures represent deeper water that was pushed toward the surface in a process called upwelling and tends to be nutrient-rich, Torres said.
The nutrient-rich water supports aggregations of krill, which in turn provide sustenance for the blue whales. In their study, the researchers were able to bring all of the pieces of this trophic pathway together to describe the relationships between oceanography, krill and whales.
As warmer ocean conditions become more frequent, this new knowledge can be used to inform and adjust spatial management of human activities in the region in an effort to reduce impacts on New Zealand blue whales, Torres said.
"Documenting information like this can really help us understand how to reduce threats to these animals," Torres said. "We need continued monitoring to understand how these whales will respond to both the changing climate and human impacts."
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Researchers find CBD improves arthritis symptoms in dogs

BAYLOR COLLEGE OF MEDICINE
NEWS RELEASE 28-MAY-2020

A team led by researchers at Baylor College of Medicine in collaboration with Medterra CBD conducted the first scientific studies to assess the potential therapeutic effects of cannabidiol (CBD) for arthritic pain in dogs, and the results could lead the way to studying its effect in humans. Researchers focused first on these animals because their condition closely mimics the characteristics of human arthritis, the leading cause of pain and disability in the U.S. for which there is no effective treatment.

Published in the journal PAIN, the study first showed both in laboratory tests and mouse models that CBD, a non-addictive product derived from hemp (cannabis), can significantly reduce the production of inflammatory molecules and immune cells associated with arthritis. Subsequently, the study showed that in dogs diagnosed with the condition, CBD treatment significantly improved quality of life as documented by both owner and veterinarian assessments. This work supports future scientific evaluation of CBD for human arthritis.

"CBD is rapidly increasing in popularity due to its anecdotal health benefits for a variety of conditions, from reducing anxiety to helping with movement disorders," said corresponding author Dr. Matthew Halpert, research faculty in the Department of Pathology and Immunology at Baylor. "In 2019, Medterra CBD approached Baylor to conduct independent scientific studies to determine the biological capabilities of several of its products."

In the current study, Halpert and his colleagues first measured the effect of CBD on immune responses associated with arthritis, both in human and murine cells grown in the lab and in mouse models. Using Medterra tinctures, they found that CBD treatment resulted in reduced production of both inflammatory molecules and immune cells linked to arthritis.

The researchers also determined that the effect was quicker and more effective when CBD was delivered encapsulated in liposomes than when it was administered 'naked.' Liposomes are artificially formed tiny spherical sacs that are used to deliver drugs and other substances into tissues at higher rates of absorption.

Halpert and colleagues next assessed the effect of naked and liposome-encapsulated CBD on the quality of life of dogs diagnosed with arthritis.

"We studied dogs because experimental evidence shows that spontaneous models of arthritis, particularly in domesticated canine models, are more appropriate for assessing human arthritis pain treatments than other animal models. The biological characteristics of arthritis in dogs closely resemble those of the human condition," Halpert said.

Arthritis is a common condition in dogs. According to the American Kennel Club, it affects one out of five dogs in the United States.

The 20 client-owned dogs enrolled in the study were seen at Sunset Animal Hospital in Houston. The dog owners were randomly provided with identical unidentified medication bottles that contained CBD, liposomal CBD, or a placebo. Neither the owners nor the veterinarian knew which treatment each dog received.

After four weeks of daily treatment, owners and veterinarians reported on the condition of the dogs, whether they observed changes in the animals' level of pain, such as changes related to running or gait. The dogs' cell blood count and blood indicators of liver and kidney function also were evaluated before and after the four weeks of treatment.

"We found encouraging results," Halpert said. "Nine of the 10 dogs on CBD showed benefits, which remained for two weeks after the treatment stopped. We did not detect alterations in the blood markers we measured, suggesting that, under the conditions of our study, the treatment seems to be safe."

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The findings support conducting studies to evaluate CBD for the treatment of human arthritis.

Other contributors to this work include Chris D. Verrico, Shonda Wesson, Vanaja Konduri, Colby Hofferek, Jonathan Vazquez-Perez, Emek Blair, Kenneth Dunner Jr, Pedram Salimpour, William K. Decker. The authors are associated with Baylor College of Medicine, Sunset Animal Hospital, Valimenta Labs, University of Texas MD Anderson Cancer Center and Boston University School of Medicine.

This study was funded in part by a sponsored research agreement between Medterra CBD Inc and Baylor College of Medicine. This project also was supported in part by the Cytometry and Cell Sorting Core at Baylor College of Medicine with funding from the NIH (grants AI036211, CA125123 and RR024574).

Decker, Halpert and Konduri declare their ownership stakes in Diakonos Research, Ltd, an unrelated immuno-oncology company. Additionally, Halpert is a paid scientific advisor for Medterra CBD.

In planet formation, it's location, location, location

NASA/GODDARD SPACE FLIGHT CENTER
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IMAGE: THE BRILLIANT TAPESTRY OF YOUNG STARS FLARING TO LIFE RESEMBLES A GLITTERING FIREWORKS DISPLAY IN THIS HUBBLE SPACE TELESCOPE IMAGE. THE SPARKLING CENTERPIECE OF THIS FIREWORKS SHOW IS A GIANT... view more 
CREDIT: CREDITS: NASA, ESA, THE HUBBLE HERITAGE TEAM (STSCI/AURA), A. NOTA (ESA/STSCI) AND THE WESTERLUND 2 SCIENCE TEAM
Astronomers using NASA's Hubble Space Telescope are finding that planets have a tough time forming in the rough-and-tumble central region of the massive, crowded star cluster Westerlund 2. Located 20,000 light-years away, Westerlund 2 is a unique laboratory to study stellar evolutionary processes because it's relatively nearby, quite young, and contains a large stellar population.
A three-year Hubble study of stars in Westerlund 2 revealed that the precursors to planet-forming disks encircling stars near the cluster's center are mysteriously devoid of large, dense clouds of dust that in a few million years could become planets.
However, the observations show that stars on the cluster's periphery do have the immense planet-forming dust clouds embedded in their disks. Researchers think our solar system followed this recipe when it formed 4.6 billion years ago.
So why do some stars in Westerlund 2 have a difficult time forming planets while others do not? It seems that planet formation depends on location, location, location. The most massive and brightest stars in the cluster congregate in the core, which is verified by observations of other star-forming regions. The cluster's center contains at least 30 extremely massive stars, some weighing up to 80 times the mass of the Sun. Their blistering ultraviolet radiation and hurricane-like stellar winds of charged particles blowtorch disks around neighboring lower-mass stars, dispersing the giant dust clouds.
"Basically, if you have monster stars, their energy is going to alter the properties of the disks around nearby, less massive stars," explained Elena Sabbi, of the Space Telescope Science Institute in Baltimore and lead researcher of the Hubble study. "You may still have a disk, but the stars change the composition of the dust in the disks, so it's harder to create stable structures that will eventually lead to planets. We think the dust either evaporates away in 1 million years, or it changes in composition and size so dramatically that planets don't have the building blocks to form."
The Hubble observations represent the first time that astronomers analyzed an extremely dense star cluster to study which environments are favorable to planet formation. Scientists, however, are still debating whether bulky stars are born in the center or whether they migrate there. Westerlund 2 already has massive stars in its core, even though it is a comparatively young, 2-million-year-old system.
Using Hubble's Wide Field Camera 3, the researchers found that of the nearly 5,000 stars in Westerlund 2 with masses between 0.1 to 5 times the Sun's mass, 1,500 of them show fluctuations in their light as the stars accrete material from their disks. Orbiting material clumped within the disk would temporarily block some of the starlight, causing brightness fluctuations.
However, Hubble detected the signature of such orbiting material only around stars outside the cluster's packed central region. The telescope witnessed large drops in brightness for as much as 10 to 20 days around 5% of the stars before they returned to normal brightness. They did not detect these dips in brightness in stars residing within four light-years of the center. These fluctuations could be caused by large clumps of dust passing in front of the star. The clumps would be in a disk tilted nearly edge-on to the view from Earth. "We think they are planetesimals or structures in formation," Sabbi explained. "These could be the seeds that eventually lead to planets in more evolved systems. These are the systems we don't see close to very massive stars. We see them only in systems outside the center."
Thanks to Hubble, astronomers can now see how stars are accreting in environments that are like the early universe, where clusters were dominated by monster stars. So far, the best known nearby stellar environment that contains massive stars is the starbirth region in the Orion Nebula. However, Westerlund 2 is a richer target because of its larger stellar population.
"Hubble's observations of Westerlund 2 give us a much better sense of how stars of different masses change over time, and how powerful winds and radiation from very massive stars affect nearby lower-mass stars and their disks," Sabbi said. "We see, for example, that lower-mass stars, like our Sun, that are near extremely massive stars in the cluster still have disks and still can accrete material as they grow. But the structure of their disks (and thus their planet-forming capability) seems to be very different from that of disks around stars forming in a calmer environment farther away from the cluster core. This information is important for building models of planet formation and stellar evolution."
This cluster will be an excellent laboratory for follow-up observations with NASA's upcoming James Webb Space Telescope, an infrared observatory. Hubble has helped astronomers identify the stars that have possible planetary structures. With Webb, researchers can study which disks around stars are not accreting material and which disks still have material that could build up into planets. This information on 1,500 stars will allow astronomers to map a path on how star systems grow and evolve. Webb also can study the chemistry of the disks in different evolutionary phases and watch how they change, and help astronomers determine what influence environment plays in their evolution.
NASA's Nancy Grace Roman Space Telescope, another planned infrared observatory, will be able to perform Sabbi's study on a much larger area.? Westerlund 2 is just a small slice of an immense star-formation region. These vast regions contain clusters of stars with different ages and different densities. Astronomers could use Roman Space Telescope observations to start to build up statistics on how a star's characteristics, like its mass or outflows, affect its own evolution or the nature of stars that form nearby. The observations could also provide more information on how planets form in tough environments.
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Sabbi's team's results appeared in The Astrophysical Journal.
The Hubble Space Telescope is a project of international cooperation between NASA and ESA (European Space Agency). NASA's Goddard Space Flight Center in Greenbelt, Maryland, manages the telescope. The Space Telescope Science Institute (STScI) in Baltimore conducts Hubble science operations. STScI is operated for NASA by the Association of Universities for Research in Astronomy in Washington, D.C.
Claire Andreoli
NASA's Goddard Space Flight Center, Greenbelt, Md.
301-286-1940
claire.andreoli@nasa.gov
Donna Weaver / Ray Villard
Space Telescope Science Institute, Baltimore
410-338-4493 / 410-338-4514
dweaver@stsci.edu / villard@stsci.edu
Elena Sabbi
Space Telescope Science Institute, Baltimore
sabbi@stsci.edu

Study questions benefits of social networks to disaster response

Communication within groups not as helpful as anticipated
CARNEGIE MELLON UNIVERSITY
Hirokazu Shirado, an assistant professor in Carnegie Mellon University's Human-Computer Interaction Institute, said he had expected his experiments to show that social networks, such as neighbors, work groups and extended families, would improve decision-making by giving people actionable information.
"What we found is that social networks make things worse," said Shirado, who began the research while a member of the Human Nature Lab at Yale University. A paper on their work appeared this week in the Proceedings of the Royal Society A.
Gathering data about social networks in the midst of a crisis is difficult, so Shirado devised a game in which online participants had an economic stake in making a decision whether to evacuate in the face of danger. He recruited 2,480 subjects and organized them into 108 groups, comparing how networked groups and isolated individuals compared in their decision making.
Participants received $2 at the outset of the 75-second experiment. If nothing happened, they could keep the $2 at the end. But if there was an impending disaster, they could leave the game and retain $1. If they failed to evacuate and disaster struck, they lost everything. They also received 10 cents for every other player who made a correct decision on whether to leave the game.
The participants thus had every incentive to choose correctly and were encouraged to communicate with each other. One member of each social network group also received the correct information about impending danger.
Compared with the isolated individuals, the networked players consistently tended to resist evacuation, regardless of whether the danger was real or not. Communication didn't improve decision-making so much as it delayed it, Shirado said. The networked players also generated misinformation, even though nobody had an incentive to do so.
One of the problems, he said, is that players didn't realize that they often used different strategies. A player who accepts "no news is good news," for instance, might think that all is safe simply because he hasn't heard anything. He might then send "safe" signals to other members of the group even though danger lurked. In other cases, players might be unable to learn the truth because the players adjacent to them all had bad information.
Shirado has used the same game as an educational tool in his CMU classes, including one instance just before the onset of the COVID-19 pandemic. He recalled one student was skeptical, arguing that there was no reason why the players couldn't choose correctly. But about 70 percent of the students -- including the skeptic -- erred in their decisions.
"Inside the networks, people could not understand why this was happening," he added.
Social media -- one type of social network -- was not included in the study, but might actually improve performance, Shirado said. Though individuals tend to follow like-minded people on social media, it's also easy to connect with others who might fall outside normal social networks, providing a way around some of the barriers that form within networks.
Shirado said he hopes to find ways of improving the performance of social networks.
"We cannot live without social networks," he explained. "I'm interested in how social networks can provide a benefit to individuals."
He acknowledged that one of the shortcomings of his experiment is that it was too simple and involved people who were randomly assigned into networks. Future experiments will require players to play several times with the same network of individuals, so they might learn who to trust.
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The Robert Wood Johnson Foundation, Tata Consultancy Services, the Nomis Foundation, the National Institute of Social Sciences and the National Institutes of Health provided support for this resea