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Monday, March 11, 2024

Scientists make shocking claim dark matter may really be an alternate shadow universe

Dark matter has proved an elusive concept to scientists, with some claiming it does not even exist. Now, researchers think the phenomenon could actually be part of an alternate universe.


By JOHN MAC GHLIONN
 Sun, Mar 10, 2024

The behaviour of galaxies would be inexplicable without the existence of dark matter 
(Image: Getty)

Scientists believe that dark matter could be viewed as an alternative universe following a breakthrough study.

The new paper by Dr. Arushi Bodas, a postdoctoral fellow at the University of Chicago’s Enrico Fermi Institute, and his colleagues, states that dark matter could and possibly should be viewed as a distorted alternate universe that never fully developed.

But before discussing the paper, it’s important to understand just how mysterious dark matter really is.

That's easier said than done, however.

Despite it constituting more than 80 percent of all matter in the universe, scientists have yet to observe dark matter, Its existence is inferred because the behavior of stars, planets, and galaxies would be wholly inexplicable without its presence.

Dark matter is difficult to observe; in fact, it’s completely imperceptible. It emits zero light or energy, making it undetectable by conventional sensors and detectors.

Scientists believe its composition is the key to understanding its mysterious nature. Visible matter, also known as baryonic matter, is composed of subatomic particles called baryons, which consist of protons, neutrons, and electrons. The composition of dark matter, on the other hand, remains speculative.

Potentially, it could consist of baryons, but it could also be composed of non-baryonic matter, which refers to different types of particles. The prevailing belief among scientists is that dark matter is primarily composed of non-baryonic matter. Another potential candidate is neutralinos, hypothetical particles that are heavier and slower than neutrinos, although they have yet to be observed.

Sterile neutrinos are also considered as a candidate for dark matter. Neutrinos are particles that do not contribute to regular matter. While a stream of neutrinos emanates from the sun, they rarely interact with normal matter and pass through the Earth and billions of inhabitants. Among the three known types of neutrinos, the sterile neutrino is proposed as a potential dark matter candidate. It would only interact with regular matter through gravity.

The most recent hypothesis proposes that dark matter exists in a distorted parallel universe within our own, where atoms are unable to come together. In the realm of ordinary matter, protons and neutrons possess almost identical masses, creating the necessary conditions for the formation of stable atoms.

The recent study proposes the existence of a potential shadow universe where protons and neutrons have asymmetrical masses, resulting in a chaotic mix of subatomic particles that rarely interact. In other words, the polar opposite of how conventional matter operates. This phenomenon could also clarify why dark matter does not aggregate.

Ever since astronomers initially suspected the presence of dark matter in the 1930s, debates surrounding what it is (and isn’t) have raged. Observations indicate that it surpasses ordinary matter by a ratio of 6 to 1. Galaxies and galaxy clusters are surrounded by massive spheres, known as "halos," of dark matter.

To remain undetected, astronomers theorize that this substantial amount of material must be composed of particles that have minimal interaction with ordinary matter or even with each other. Their primary function is to provide the gravitational framework for luminous matter. Astronomers believe that these halos were created in the early stages of cosmic history and subsequently attracted ordinary matter, which, due to its diverse range of behaviors, evolved into complex structures, while dark matter, being inert, remained unchanged.

Dark energy, on the other hand, seems to only serve the purpose of accelerating cosmic expansion, and the existing evidence suggests that it has remained constant throughout the existence of the universe.

Although a minority of scientists reject the idea of dark matter, there is now a plethora of evidence supporting its existence, with one of the most straightforward explanations involving the rotation of galaxies.

As Dr. Don Lincoln, a senior scientist at Fermilab, America’s leading particle physics laboratory, has noted, despite the gravitational pull towards the Sun, the planets' velocities result in nearly circular orbits.

The balance between velocity and gravity dictates that planets farther from the Sun move at a slower pace compared to those in closer proximity. Similarly, in galaxies, stars follow a similar pattern, with the laws of physics making analogous predictions.

Specifically, stars located further from the galactic center should move at a slower pace than those nearer to it.

However, observations by astronomers reveal that stars in the outer regions of galaxies move faster than anticipated. If the laws of gravity and motion hold true, the only plausible explanation is the presence of additional, unseen matter intensifying the gravitational force experienced by these rapidly moving stars.

The new paper by Dr. Bodas and his colleagues is just the latest to solidify the "dark matter really does exist' thesis.


Controversial new theory of gravity rules out need for dark matter


Exclusive: Paper by UCL professor says ‘wobbly’ space-time could instead explain expansion of universe and galactic rotation




Hannah Devlin 
THE GUARDIAN
Science correspondent
Sat 9 Mar 2024 

Dark matter is supposed to account for 85% of the mass in the universe, according to conventional scientific wisdom. But proponents of a radical new theory of gravity, in which space-time is “wobbly”, say their approach could render the elusive substance obsolete.

The proposition, outlined in a new paper, raises the controversial possibility that dark matter, which has never been directly observed, is a mirage that a substantial portion of the physics community has been chasing for several decades. The theory is viewed as quite left-field and is yet to be thoroughly tested, but the latest claims are creating a stir in the world of physics.

Announcing the paper on X, Prof Jonathan Oppenheim, of University College London, said: “Folks, something seems to be happening. We show that our theory of gravity … can explain the expansion of the universe and galactic rotation without dark matter or dark energy.”

There are multiple lines of evidence for dark matter, but its nature has remained mysterious and searches by the Large Hadron Collider have come up empty-handed. Last year, the European Space Agency launched a mission, Euclid, aiming to produce a cosmic map of dark matter.

The latest paper, published on the Arxiv website and yet to be peer-reviewed, raises the question of whether it even exists, drawing parallels between dark matter and flawed concepts of the past, such as “the ether”, an invisible substance that was thought to permeate all of space.

“In the absence of any direct evidence for dark energy or dark matter it is natural to wonder whether they may be unnecessary scientific constructs like celestial spheres, ether, or the planet Vulcan, all of which were superseded by simpler explanations,” it states. “Gravity has a long history of being a trickster.”

In this case, the simpler explanation being proposed is Oppenheim’s “postquantum theory of classical gravity”. The UCL professor has spent the past five years developing the approach, which aims to unite the two pillars of modern physics: quantum theory and Einstein’s general relativity, which are fundamentally incompatible.

Oppenheim’s theory envisages the fabric of space-time as smooth and continuous (classical), but inherently wobbly. The rate at which time flows would randomly fluctuate, like a burbling stream, space would be haphazardly warped and time would diverge in different patches of the universe. The theory also envisions an intrinsic breakdown in predictability.


The paper, by Oppenheim and Andrea Russo, a PhD candidate at UCL, claims this take on the universe could explain landmark observations of rotating galaxies that led to the “discovery” of dark matter. Stars at the edges of galaxies, where gravity is expected to be weakest based on visible matter, ought to be rotating more slowly than stars at the centre. But in reality, the orbital motion of stars does not drop off. From this, astronomers inferred the presence of a halo of unseen (dark) matter exerting a gravitational pull.

In Oppenheim’s approach the additional energy required to keep the stars locked in orbit is provided by the random fluctuations in spacetime, which in effect add in a background hum of gravitation. This would be negligible in a high gravity interaction, such as the Earth orbiting the Sun. But in low gravity situations, such as the fringes of a galaxy, the phenomenon would dominate – and cumulatively could account for the majority of the energy in the universe.

“We show that it can explain the expansion of the universe and galactic rotation curves without the need for dark matter or dark energy,” Oppenheim said on X. “We do urge caution, however, since there is other indirect evidence for dark matter, so further calculations and comparison with data are needed. But if it holds, it would appear that 95% of the energy in the universe is due to the erratic nature of spacetime, signalling either a fundamental breakdown in predictability of physics, or we are immersed in an environment which does not obey the laws of classical or quantum theory.”

Not everyone is convinced, including the well-known theorists Prof Carlo Rovelli and Prof Geoff Penington, who have signed a 5,000:1 odds bet with Oppenheim against his theory being proven correct.

“I think it’s good that physicists explore a wide variety of approaches to very difficult problems like combining quantum mechanics with gravity,” said Penington.

“Personally, I don’t think this particular approach is likely to be the correct one. I’ve obviously put my money where my mouth is on that front and there is nothing new in the recent papers that would make me change that assessment.”

Others are more enthusiastic. “I think the authors are on to something really interesting here, exploring some beautiful and novel ideas,” said Prof Andrew Pontzen, a cosmologist at University College London. “However, the challenge for replacing dark matter is that there are so many different lines of evidence that suggest its presence. So far they have only addressed one of these lines. Only time will tell whether the new ideas can truly explain the huge variety of phenomena that point towards dark matter.”








Wednesday, March 06, 2024

 

Decoding cryptocurrency regulation in the legibility framework


Researchers present a new framework to discuss the controversial regulation of cryptocurrency across different countries


Peer-Reviewed Publication

WASEDA UNIVERSITY

Legibility and cryptocurrency markets 

IMAGE: 

LEGIBILITY IS A USEFUL CONCEPT THAT CAN EXPLAIN HOW MARKET REGULATIONS EVOLVE OVER TIME THROUGH THE INTERPLAY OF MARKET DEMAND FOR AND STATE SUPPLY OF REGULATION. IT CAN EXPLAIN THE PUZZLING CROSS-NATIONAL DIFFERENCES IN CRYPTOCURRENCY REGULATION.

view more 

CREDIT: JACK SEDDON FROM WASEDA UNIVERSITY AND MILES KELLERMAN FROM LEIDEN UNIVERSITY



Since its introduction, cryptocurrency governance has been one of the most controversial global financial topics. While some countries have established elaborate regulations for cryptocurrencies, many countries are still reluctant to oversee the markets, and some have outright banned them. Most studies suggest that public agencies naturally want to regulate markets and bring them into their purview. However, the significant differences in cryptocurrency regulation over the world call this view into question. Moreover, these differences cannot be explained by the development of the financial market and capacity of the state. This naturally leads to the question - what is the cause of these differences and what drives market regulation?

To answer these questions, Associate Professor Jack Seddon from the School of Political Science and Economics at Waseda University and Associate Professor Miles Kellerman from Leiden University’s Institute of Security and Global Affairs introduce the concept of ‘legibility’ to the analysis of financial markets. “The widespread debate over the extent to which cryptocurrencies should be regulated can be better understood as a political battle over whether to make private markets "legible" to the state. Our framework conceptualizes this dynamic as a balance of two variables: market demand for regulation and state supply,” explained Dr. Seddon. Their novel framework was presented in a study published in the journal Business and Politics on February 05, 2024. The study was funded by The Law, Politics and Economics of Financial Benchmarks: JSPS KAKENHI Grant Number 20K13438.

In this innovative framework, the supply and demand variables together determine the ideal-typical states of market legibility. The demand side represents the competing interests of the various market actors over seeking legibility and the supply side shows how likely the state is to regulate a specific market. When both demand and supply are low, the markets are in a state of pure illegibility with no regulation. In contrast, when both demand and supply are high, as is the case for most real markets, the markets are in a state of collaborative legibility.

Additionally, when the state supply is high and market demand is low, the markets enter contested legibility, where the state wants to bring the market into the legal purview, but market actors resist it. Alternatively, when the demand is high and the state supply is low, contested illegibility occurs. The researchers also presented an expected progression of markets through these legibility states, over time. According to this framework, most markets start in the state of pure illegibility and over time go through either contested legibility or illegibility to finally attain collaborative legibility.

They utilized this framework to study the evolution of the cryptocurrency market in the United States, European Union, and Japan. Their analysis revealed that all three went through the expected stages of legibility, albeit at different rates. The United States, for example, is currently in the stage of contested legibility, while the EU progressed from contested legibility to collaborative legibility. Japan, unlike the other two, quickly transitioned from pure illegibility to collaborative legibility. Furthermore, the findings also showed that once the final state is achieved, markets do not tend to regress.

These results suggest that legibility is a powerful concept that can also be applied to understand other markets. In the future, the researchers aim to study other markets and countries to realize their full generalizability. Emphasizing the significance of this study, Dr. Kellerman said, “This study is highly relevant to pressing regulatory concerns. For example, a prolonged state of contested legibility in the crypto market can delay the introduction of regulations that protect consumers. By mapping patterns of contestation over legibility, our framework takes a first step towards better understanding the political economy of financial regulation.

 

***

Reference

DOI: https://doi.org/10.1017/bap.2023.38

Authors: Miles Kellerman1 and Jack Seddon2

Affiliations         

1Institute of Security and Global Affairs, Leiden University, Netherlands

2School of Political Science and Economics, Waseda University, Japan

 

About Waseda University

Located in the heart of Tokyo, Waseda University is a leading private research university that has long been dedicated to academic excellence, innovative research, and civic engagement at both the local and global levels since 1882. The University has produced many changemakers in its history, including nine prime ministers and many leaders in business, science and technology, literature, sports, and film. Waseda has strong collaborations with overseas research institutions and is committed to advancing cutting-edge research and developing leaders who can contribute to the resolution of complex, global social issues. The University has set a target of achieving a zero-carbon campus by 2032, in line with the Sustainable Development Goals (SDGs) adopted by the United Nations in 2015. 

To learn more about Waseda University, visit https://www.waseda.jp/top/en  

 

About Associate Professor Jack Seddon

Jack Seddon is currently the Associate Professor of International Political Economy at the School of Political Science and Economics at Waseda University, Japan. He received his master’s and Ph.D. from the University of Oxford in 2012 and 2016, respectively. He is also the Principal Investigator of the Sterling Area Revisited Project, funded by an ESRC New Investigator Grant. His research focuses on international political economy and economic history. He has also co-authored book chapters on finance and governance, published by Oxford University Press, London: Edward Elgar and Cambridge University Press.

 

About Associate Professor Miles Kellerman

Miles Kellerman is currently the Assistant Professor of International Organization and Multi-level Governance at Leiden University’s Institute of Security and Global Affairs. He received his master’s and Ph.D. from the University of Oxford in 2015 and 2020, respectively. His research primarily focuses on economic crime. His other research interests include economic statecraft, multilateral development banking, and the regulation of global capital markets. Outside academia he has worked professionally on financial crime prevention both within a global bank and as a consultant in London, New York, Washington D.C., and Amsterdam.

Saturday, February 17, 2024

Bitcoin ETFs poised for US pension plan inflows, Standard Chartered analyst says


Brian McGleenon
Thu, 15 February 2024 

Bitcoin (BTC-USD) spot ETFs could see an influx of capital from US pension plan managers, according to an analyst. This expectation could indicate a broader acceptance and adoption of bitcoin-related investments within retirement portfolios.

On this week's episode of Yahoo Finance Future Focus, Standard Chartered (STAN.L) head of crypto research Geoff Kendrick shared his insights into the evolving cryptocurrency landscape where traditional finance incumbents, such BlackRock (BLK) and Franklin Templeton (BEN), are participating via the recently launched spot bitcoin exchange traded funds (ETFs).

Read more: Crypto live prices

Following the increased inflows from asset managers into the eleven existent spot bitcoin ETFs, Kendrick expects participants from the US 401(k) market, such as retirement fund managers, to begin allocating into the newly launched funds.

"What we now see in the US is the 401(K) market, such as pensions, enter bitcoin and other assets in this space, when we get the spot ether ETF in May, for the first time," Kendrick told Yahoo Finance.

According to data from the Investment Company Group (ICI), 401(k) plans hold $6.9tn (£5.5tn) in assets, in more than 710,000 plans, on behalf of about 70 million active participants and millions of former employees and retirees.

Spot bitcoin ETF inflows

Kendrick told Yahoo Finance UK that in total he expects "around $50bn to $100bn in net inflows into spot bitcoin ETFs in 2024."

A spot bitcoin ETF is a financial product that investors hope will pave the way for mainstream capital to flood the crypto market. Currently, the indications are favorable, with fund managers having allocated over $4bn in net inflows to the eleven spot bitcoin ETFs since they were approved by the US Securities and Exchange Commission (SEC) on 11 January.

Spot ether ETFs anticipated


Kendrick also expressed optimism about the possibility of a spot ether ETF (ETH-USD) being approved by the SEC, marking out 23 May as a potential date. He added that this is expected to contribute to positive market sentiment and suggested that net inflows into anticipated spot ether ETFs in 2024 could reach between $20bn and $35bn by the end of year.

Read more: Bitcoin success with SEC fuels anticipation for ether spot ETF

Kendrick noted that the excess demand might surpass that seen surrounding the approval of bitcoin's spot ETFs. He emphasised the smaller size of proxies, such as the Grayscale Ethereum Trust, which may impact supply and demand dynamics for ether.

"It's likely the price impact will be even greater for ether than it has been for bitcoin in the run-up to the approval of a spot ether ETF. That's partly because the proxies, such as the European ETFs, the Canadian ETFs and the Grayscale Trust for ether are smaller as a percentage of market cap than they are in bitcoin. So the build up of excess demand is more likely to be even larger for ether than it was for bitcoin," he said.

Kendrick said that, despite recent volatility in US Treasury yields and a potential delay in a US Federal Reserve rate cut, bitcoin and ether, along with other risk assets, have performed well.

As the market broadens, he anticipates increased liquidity and the emergence of options for both spot bitcoin and spot ether ETFs, signaling a new phase in the maturity of the cryptocurrency investment landscape.

Saturday, January 27, 2024

Flame-retardant chemicals may increase risk of preterm birth, higher birth weight


Rutgers Health participated in a federal study that found certain organophosphate esters were linked to increased risk of early birth, especially in girls


Peer-Reviewed Publication

RUTGERS UNIVERSITY





Pregnant women exposed to specific classes of flame-retardant chemicals may face an increased risk of preterm birth, especially for baby girls, or higher birth weights, according to a Rutgers Health researcher.

Emily Barrett, professor and vice chair of the Department of Biostatistics and Epidemiology at the Rutgers School of Public Health and a member of the Rutgers Environmental and Occupational Health Sciences Institute, took part in a study that was published in Environmental Health Perspectives and funded by the Environmental influences on Child Health Outcomes (ECHO) Program at the National Institutes of Health.

Manufacturers commonly use organophosphate esters (OPEs) in products such as furniture, baby items, electronics, clothes and building materials to prevent fires and make plastics more flexible. People can come into contact with OPEs in various ways, including swallowing or breathing indoor dust or absorbing it through the skin.

In the past decade, OPEs increasingly have been used as flame retardants after polybrominated diphenyl ether (PBDE) flame retardants were phased out because of health risks. ECHO researchers wanted to learn how these now more widespread OPE chemicals might affect pregnancy outcomes such as preterm birth and birth weight.

“This is another regrettable case where new chemicals were introduced into consumer products without really understanding their health impacts,” said Barrett, a coauthor of the study. “Knowing now that OPE exposure is associated with adverse birth outcomes, we have to ask ourselves, ‘What are the downstream impacts on children’s health?’”

ECHO researchers found more than 85% of the study participants had three specific markers of OPE exposure in their bodies. Those three substances – diphenyl phosphate (DPHP), a combination of dibutyl phosphate and di-isobutyl phosphate (DBUP/DIBP) and bis(1,3-dichloro-2-propyl) phosphate – were associated with shorter pregnancies and higher risks of preterm birth only among female infants. Among male infants, higher concentrations of DPHP were associated with longer pregnancies.

Babies born to mothers with detectable levels of three other OPE markers – bis(1-chloro-2-propyl) phosphate, bis(2-methylphenyl) phosphate, and dipropyl phosphate – tended to have higher birth weights compared with those whose mothers had no detectable levels of these substances. Babies with a higher birth weight might be more likely to have jaundice, breathing problems or congenital disorders.

Researchers measured a total of nine OPE markers in urine samples collected from 6,646 pregnant participants across 16 ECHO Cohort Study Sites, often during their third or second trimesters. The researchers assessed birth outcomes, including the length of pregnancy and birth weight, using medical records or parent reports.

“These substances tend to stay in the body for short periods, usually just hours to days,” said Deborah Bennett at the University of California, Davis, who led the study. “Conducting more thorough studies with various urine tests can help us figure out how they might be linked to birth outcomes.”

Wednesday, January 24, 2024

   

 

Multi-generational toxicant exposures show cumulative, inherited health effects


Peer-Reviewed Publication

WASHINGTON STATE UNIVERSITY




While exposure to a single substance like DDT has been shown to create inherited disease susceptibility, a recent study in animals found exposure to multiple different toxicants across generations can amplify those health problems.

In the study, published in the journal Environmental Epigenetics, an initial generation of pregnant rats was exposed to a common fungicide, then their progeny to jet fuel and the following generation to DDT. When those rats were then bred out to a fifth unexposed generation, the incidence of obesity as well as kidney and prostate diseases in those animals were compounded, rising by as much as 70%.

Researchers also found that their epigenetics, molecular processes independent of DNA that influence gene expression, were also greatly altered.

“We looked at multiple-generation exposures because these types of things are going on routinely, and previous research has only looked at single exposures,” said Michael Skinner, a WSU biology professor and the study’s corresponding author. “We found that if multiple generations get different exposures, then eventually there’s an amplification or compounded effect on some diseases.”

The study did show that for other diseases, those associated with the ovaries and the testes, the incidence rose in the first generation of progeny but appeared to plateau with the additional generational exposures.

Skinner and his colleagues also conducted epigenetic analysis of each generation of the animals, finding that the toxicant exposures shifted their entire epigenetics dramatically. Along with changes to genes themselves, inherited epigenetics which influence gene expression, are considered to have a significant impact on evolution.

“When we made the comparisons with different generations, we did not find a lot of overlap in epigenetics. In other words, every time each generation had a new exposure, it appeared to reprogram the whole epigenome,” Skinner said.

While the study does not exactly mimic what may have happened to human generations, people in the US have potentially been exposed to these particular toxicants at different times. The authors note a likely sequential exposure over human generations might involve an exposure to DDT which was widely used in the 1950s, then plastics in the 1970s, followed by many modern herbicides still in use today.

The study provides evidence that multiple toxicant exposures of past human generations likely had a compounded impact on grandchildren and great-grandchildren. Knowing about these possible impacts can help people and doctors address potential diseases before they develop, Skinner said.

Researchers including Skinner’s lab at WSU have been working to identify epigenetic biomarkers for inherited health conditions in humans including for obesityautism and pre-term birth.

“We need to know to what degree our past generations activities that have affected us,” Skinner said. “We cannot necessarily fix this problem, but it's important to know that it happened so that we can try to better treat potential health problems through preventative medicine.”

This research received support from the John Templeton Foundation and the National Institutes of Health.

JOURNAL

DOI

Forever chemicals" in German drinking water - a hidden threat unveiled


Peer-Reviewed Publication

NANJING INSTITUTE OF ENVIRONMENTAL SCIENCES, MEE

Graphical abstract. 

IMAGE: 

GRAPHICAL ABSTRACT.

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CREDIT: ECO-ENVIRONMENT & HEALTH



PFAS, commonly known as "forever chemicals," are a group of man-made substances that have been used in various industries since the 1940s due to their resistance to heat, water, and oil.These chemicals are found in products like non-stick cookware, waterproof fabrics, firefighting foams, and food packaging.Their persistence in the environment and their ability to accumulate in human and animal tissue make them a concern for potential adverse health impacts. Despite their widespread use, the knowledge about pose potential risks to drinking water quality,  especially in Germany, has been limited.

In a landmark study (https://doi.org/10.1016/j.eehl.2023.08.004) published in "Eco-Environment & Health" (Volume 2, 2023), researchers screened German drinking water for 26 per- and polyfluoroalkyl substances (PFAS). This effort, notably supported by residents, marks a significant step in understanding PFAS presence in drinking water.

The study involved collecting 89 drinking water samples from various locations in Germany, analyzing them for 26 different PFAS using high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS). The findings revealed that while the 20 recently regulated PFAS were below the detection limit, the sum concentrations varied widely, with some samples exceeding the threshold for certain PFAS.

This research is pivotal in informing future regulatory decisions and public health guidelines. It highlights the need for ongoing surveillance and stricter controls on PFAS in drinking water.

Dr. Aki Sebastian Ruhl, emphasizes the importance of this study in providing a comprehensive view of PFAS distribution in drinking water across Germany, a crucial aspect in evaluating environmental and health risks.

The collaborative effort in this study has provided valuable insights into PFAS levels in German drinking water, laying the groundwork for future environmental and public health initiatives, and underscores the necessity for further research to understand the long-term implications of PFAS in drinking water and to develop more efficient removal methods.

The collaborative effort in this study has provided valuable insights into PFAS levels in German drinking water, laying the groundwork for future environmental and public health initiatives, and underscores the necessity for further research to understand the long-term implications of PFAS in drinking water and to develop more efficient removal methods.

###

References

DOI

10.1016/j.eehl.2023.08.004

Original Source URL

https://doi.org/10.1016/j.eehl.2023.08.004

Funding information

The project Spu-TriDa was funded by the German Ministry of Health.

About Eco-Environment & Health

Eco-Environment & Health (EEHis an international and multidisciplinary peer-reviewed journal designed for publications on the frontiers of the ecology, environment and health as well as their related disciplines. EEH focuses on the concept of "One Health" to promote green and sustainable development, dealing with the interactions among ecology, environment and health, and the underlying mechanisms and interventions. Our mission is to be one of the most important flagship journals in the field of environmental health.

Exposure to flame retardants linked to premature birth, higher birth weight


Organophosphate ester flame retardants are found in building materials, furniture, baby products, electronics and textiles


Peer-Reviewed Publication

UNIVERSITY OF CALIFORNIA - DAVIS HEALTH

Deborah Bennett UC Davis 

IMAGE: DEBORAH BENNETT, SENIOR AUTHOR OF THE STUDY, IS A PROFESSOR OF ENVIRONMENTAL HEALTH IN THE UC DAVIS DEPARTMENT OF PUBLIC HEALTH SCIENCES. view more 

CREDIT: UC DAVIS HEALTH




(SACRAMENTO, Calif.) — In the largest study of its kind, researchers at UC Davis Health found that exposure to organophosphate ester flame retardants during pregnancy was associated with preterm birth, especially among females. The chemicals were also linked to higher birth weight, a concern for increased obesity risk. The major new research study was published in Environmental Health Perspectives.

“The importance of this study lies in unraveling the potential impact of exposure to environmental chemicals during pregnancy on fetal development. Our findings guide our understanding of how these chemicals may be silently seeding lasting challenges for the health of the next generation,” said Jiwon Oh, first author of the study and a postdoctoral scholar in the Department of Public Health SciencesDivision of Environmental and Occupational Health.

OPEs phased in as polybrominated flame retardants phased out

In the mid-2000s, one class of chemicals, polybrominated diphenyl ether flame retardants, were gradually phased out of use due to concerns about their potential toxicity.

Organophosphate esters, or OPEs, gradually took their place. They are now widely used in foams found in furniture, baby products, electronics, textiles and building materials to prevent fires and make plastics more flexible.

Because of their chemical structure, OPEs slowly degrade and become part of dust. Individuals are exposed to OPEs through their skin or when they ingest or inhale indoor dust.

The chemicals are frequently detected in urine samples from the U.S. general population, including samples from pregnant people. For this study, the researchers wanted to determine what impact OPEs might have on fetal development during pregnancy.

Research conducted across U.S.

Researchers at multiple institutions, including UC Davis, conducted the study. It included 6,646 mother-child pairs from 16 cohorts across the U.S. from the Environmental Influences on Child Health Outcome (ECHO) study. The participants came from various regions and had diverse backgrounds.

Researchers measured nine OPE biomarkers in urine samples of pregnant people collected between 2007 and 2020, with most samples obtained during the second and third trimesters.

They assessed birth outcomes, including gestational age at birth and birth weight, primarily using medical records or parent reports.

Preterm births and greater birth weight

The researchers found three of the nine OPEs were associated with increased risks of preterm birth (before 37 weeks of pregnancy), especially among female newborns. These included:

  • dibutyl phosphate
  • di-isobutyl phosphate
  • bis(butoxyethyl) phosphate

Preterm births can put infants at risk of health issues, including breathing and feeding problems, developmental delays, cerebral palsy, and vision and hearing problems.

Three other OPEs — bis(1-chloro-2-propyl) phosphate, bis(2-methylphenyl) phosphate, and dipropyl phosphate — were linked to greater birth weight-for-gestational-age.

High birth weight is associated with childhood obesity, which increases the risk of health conditions like diabetes and cardiovascular disease.

“There were over 6,000 pregnancies included in this study, and with such a large study, we are very confident of our findings,” said Deborah Bennett, senior author of the study and a professor of environmental health in the Department of Public Health Sciences. “Policy options to reduce exposure to organophosphate ester flame retardants should be considered.”

OPEs are metabolic and endocrine-disrupting chemicals

The researchers noted that OPEs may affect thyroid hormone levels and cause inflammation and oxidative stress, which could play a role in the preterm births. OPEs are also endocrine disruptors, so they may contribute to abnormal placental development, and the impact may vary based on the sex of the fetus.

“Because OPEs are from building materials, textiles, electronics and other products, consumers cannot choose products that do not contain OPEs,” Oh said. “Only policy changes and regulations can mitigate their exposure.”

Resources

 

 

Wednesday, January 10, 2024

FOREVER CHEMICALS

PFAS flow equally between Arctic Ocean and Atlantic Ocean, study finds



Peer-Reviewed Publication

AMERICAN CHEMICAL SOCIETY

PFAS flow equally between Arctic Ocean and Atlantic Ocean, study finds 

IMAGE: 

PFAS COME AND GO BETWEEN THE ARCTIC AND ATLANTIC OCEANS AT ROUGHLY EQUAL RATES.

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CREDIT: ADAPTED FROM ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS 2024, DOI: 10.1021/ACS.ESTLETT.3C00835




The frigid Arctic Ocean is far removed from the places most people live, but even so, “forever chemicals” reach this remote landscape. Now, research in ACS’ Environmental Science & Technology Letters suggests that per- and polyfluoroalkyl substances (PFAS) won't stay there indefinitely. Instead, they are transported in a feedback loop, with the Arctic Ocean potentially exporting as many PFAS to the North Atlantic Ocean as it receives, circulating the compounds around the world.

To get to the Arctic Ocean, some PFAS hitch a ride in the air and fall onto the ocean’s surface, but others enter from adjacent oceans. The potential impact of these compounds on marine organisms depends on what PFAS are present and how much, which are ever-changing as water flows between the Arctic Ocean and the North Atlantic Ocean. These waterbodies are connected by the Fram Strait, which sits to the northeast of Greenland near the Svalbard archipelago. Warm water travels north on the eastern side of the strait, and cold water flows south along the western side, providing a dynamic gateway for PFAS transportation. So, Rainer Lohmann and colleagues wanted to track the movement of PFAS in this region and identify how water circulation influences the mix of contaminants in the Arctic Ocean.

The researchers deployed passive sampling systems, which took up PFAS into a sorbent-filled microporous membrane from water as it flowed past. They put the systems at three locations in the Fram Strait, and at four depths in each location. After a year, the team retrieved the systems and measured the collected PFAS using liquid chromatography-mass spectrometry. The researchers overserved that:

  • Ten PFAS were detected in at least one passive sampler, however, one substance detected in the area by previous research teams wasn’t among them.
  • Two compounds known as PFOA and PFOS, which are being phased out, were present at the highest levels. Newer, short-chain PFAS were also routinely present.
  • Surprisingly, several PFAS were found in water below 3,000 feet deep. The team suggests that these compounds could have gotten there by attaching to particles as they fell to the seafloor.

The team calculated the amounts of PFAS flowing in each direction through the Fram Strait. Their data showed that in one year around 123 tons traveled into the Arctic Ocean and about 110 tons moved into the Atlantic Ocean. According to the researchers, these values are the largest of any pollutant reported in the strait, demonstrating how significant the back-and-forth circulation of PFAS is in the Arctic Ocean.

The authors acknowledge funding from the University of Rhode Island Sources, Transport, Exposure and Effects of PFAS (STEEP) Superfund Center, and the Alfred Wegener Institute Long Term Ecological Research Hausgarten program.

The paper’s abstract will be available on Jan. 10 at 8 a.m. Eastern time here: http://pubs.acs.org/doi/abs/10.1021/acs.estlett.3c00835

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Nafion byproduct 2 found in blood of well users near Fayetteville, NC


Peer-Reviewed Publication

NORTH CAROLINA STATE UNIVERSITY




Researchers from the GenX Exposure Study detected PFAS originating from a fluorochemical manufacturing plant – including Nafion byproduct 2 and GenX – in nearby private wells in Bladen and Cumberland Counties, N.C. PFAS refers to a group of chemicals called per- and polyfluoroalkyl substances.

“These compounds were released to the environment through air and wastewater emissions from the facility,” says Nadine Kotlarz, research scholar in the department of biological sciences at North Carolina State University, member of NC State’s Center for Human Health and the Environment (CHHE), and corresponding author of the paper.

“Air released from the facility caused the contamination of groundwater and private wells,” Kotlarz says. “In order to study how exposure to these chemicals may affect human health, we need to know the exposure levels across impacted people.”

In February 2019, the researchers recruited 153 people from this region who used 84 private wells to participate in the GenX Exposure Study. The participants lived within six miles of the fluorochemical facility. The participants provided well water and blood samples and filled out questionnaires about their well-water consumption.

The water and blood samples were screened for nine PFAS produced by the facility, including GenX and Nafion byproduct 2.

The PFAS found most frequently and at the highest concentrations in the wells included several low molecular weight PFAS (PMPA, PEPA, GenX, PFO2HxA, PFMOAA). The median concentration of GenX in the wells was 107 nanograms per liter (ng/L), 10 times higher than the U.S. Environmental Protection Agency’s (EPA) drinking water health advisory level of 10 ng/L.

However, these PFAS were not frequently detected in the private well users’ blood, even though they drank the well water.

Nafion byproduct 2, a higher molecular weight PFAS with a longer half-life, was detected frequently in wells at lower concentrations (the median concentration was 14 ng/L) and detected in more than half of participants’ blood.

“With Nafion byproduct 2, we saw that higher well-water concentration and the longer a person lived at their home correlated with higher blood levels,” Kotlarz says. “Well-water consumption is having an impact on exposure, and we know that several other PFAS were present in the wells, but due to the short half-lives of some PFAS (like GenX) in the body, we didn’t find all of the well water PFAS in blood.

“Blood levels of a chemical across a population are often used to characterize exposure,” Kotlarz says. “Without blood levels, we will need to estimate exposure to PFAS such as GenX another way in order to study their potential health effects.”

The research appears in the Journal of Exposure Science and Environmental Epidemiology. The GenX Exposure Study is supported by research funding from the National Institute of Environmental Health Sciences (1R21ES029353), NC State’s CHHE (P30 ES025128), the Center for Environmental and Health Effects of PFAS (P42 ES0310095), and the NC Policy Collaboratory. James McCord and Mark Strynar from the EPA; David Collier and Suzanne Lea from East Carolina University; Theresa Guillette of the Oak Ridge Institute for Science and Education Research; and Claire Critchley, Michael Cuffney, Zachary Hopkins, Detlef Knappe and Jane Hoppin of NC State also contributed to the work.

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Note to editors: An abstract follows.

“Per- and polyfluoroalkyl ether acids in well water and blood serum from private well users residing by a fluorochemical facility near Fayetteville, North Carolina”

DOI10.1038/s41370-023-00626-x

Authors: Nadine Kotlarz, Claire Critchley, Michael Cuffney, Zachary R. Hopkins, Detlef R.U. Knappe, Jane A. Hoppin, North Carolina State University; Theresa Guillette, Oak Ridge Institute for Science and Education Research; David Collier, C. Suzanne Lea, East Carolina University; James McCord, Mark Strynar, U.S. Environmental Protection Agency
Published: Jan. 10, 2024 in the Journal of Exposure Science and Environmental Epidemiology

Abstract:
BACKGROUND: A fluorochemical facility near Fayetteville, North Carolina, emitted per- and polyfluoroalkyl ether acids (PFEAs), a subgroup of per- and polyfluoroalkyl substances (PFAS), to air.
OBJECTIVE: Analyze PFAS in private wells near the facility and in blood from well users to assess relationships between PFEA levels in water and serum.
METHODS: In 2019, we recruited private well users into the GenX Exposure Study and collected blood and well water samples. We targeted 26 PFAS (11 PFEAs) in water and 27 PFAS (9 PFEAs) in serum using liquid chromatography-mass spectrometry. We used regression modeling to explore relationships between water and serum PFAS. For the only PFEA detected frequently in water and serum, Nafion byproduct 2, we used generalized estimating equation (GEE) models to assess well water exposure metrics and then adjusted for covariates that may influence Nafion byproduct 2 serum concentrations.
RESULTS: We enrolled 153 participants ages 6 and older (median=56 years) using 84 private wells. Most wells (74%) had ≥6 detectable PFEAs; median ∑PFEAs was 842 ng/L (interquartile range=197-1,760 ng/L). Low molecular weight PFEAs (PMPA, HFPO-DA [GenX], PEPA, PFO2HxA) were frequently detected in well water, had the highest median concentrations, but were not detectable in serum. Nafion byproduct 2 was detected in 73% of wells (median=14 ng/L) and 56% of serum samples (median=0.2 ng/mL). Cumulative dose (well concentration × duration at address) was positively associated with Nafion byproduct 2 serum levels and explained the most variability (10%). In the adjusted model, cumulative dose was associated with higher Nafion byproduct 2 serum levels while time outside the home was associated with lower levels.
SIGNIFICANCE: Serum biomarkers were not good measures of long-term exposure to low molecular weight PFEAs in a private well population. For Nafion byproduct 2, well water exposure metrics were associated with serum levels, particularly when incorporating exposure duration.