Tuesday, August 31, 2021

Mormon vaccine push ratchets up, dividing faith's members

SALT LAKE CITY (AP) — After more than a year of attending church virtually, Monique Allen has struggled to explain to her asthmatic daughter why people from their congregation of The Church of Jesus Christ of Latter-day Saints don’t wear masks. Allen said she’s taught her daughter that wearing a mask is Christlike, but now she worries her child feels like an outcast.

© Provided by The Canadian Press

Church leaders recently issued their strongest statement yet urging people to “limit the spread” by getting COVID-19 vaccines and wearing masks, but Allen said she fears it’s still not enough to convince the many families in her congregation who refuse to wear masks and have succumbed to anti-vaccine misinformation.

Members of the faith widely known as the Mormon church remain deeply divided on vaccines and mask-wearing despite consistent guidance from church leaders as the highly contagious delta variant of the coronavirus spreads.

About 65% of Latter-day Saints who responded to a recent survey said they were vaccine acceptors, meaning they've gotten at least one dose or plan to soon. Another 15% identified as hesitant, and 19% said they would not get the vaccine, according to the survey this summer from the Public Religion Research Institute, a polling organization based in Washington, and Interfaith Youth Core.

The survey found 79% of white Catholics and 56% of white Evangelical Protestants identified as vaccine acceptors.

Allen, a church member living in Wisconsin, is among a contingent who fear fellow members who refuse to get vaccinated are allowing their political views to supersede their loyalty to a faith that largely prioritizes unity and obedience.

The message she's shared with her 8-year-old daughter is that “of course Christ would wear a mask, of course he would get vaccinated because he’s a loving person," she said. "And that’s the only way you can take care of people these days is doing these simple things.”

Other church members are upset that their leaders aren’t letting them exercise their own decision-making about vaccines and masks. The Utah-based religion of 16 million members worldwide is one of many faiths grappling with how best to navigate the pandemic's lingering effects.

Divisions on masking and vaccinations in the Latter-day Saint faith appear to be tracking along political lines, with conservative members being more hesitant, said Patrick Mason, associate professor of religion at Utah State University. Mason said the church’s divide is indicative of a larger pattern in the United States of political ideologies shaping people's religious commitments.

“The common perception of Mormons and Mormonism is that when church leaders speak, church members listen and do what they’re told,” said Mason. “This has revealed sometimes how conditional that loyalty can be.”

The Latter-day Saint faith was one of the first to respond to the COVID-19 pandemic. In March 2020, church leaders suspended all church gatherings and closed temples. The church has also held three consecutive major conferences remotely since the pandemic began. The twice-yearly conference usually brings about 100,000 people to Salt Lake City over two days.

Many faith leaders have spoken in support of vaccinations, including Church President Russell M. Nelson, a former cardiologist who got the vaccine in January and encouraged members to follow his example.

Church-owned Brigham Young University in Utah has asked students to report their vaccination status but is not requiring vaccinations. Masks are required in classrooms and any indoor spaces where social distancing isn’t possible.

The church is also requiring U.S. missionaries serving in foreign countries to be vaccinated.

Regarding masks at services, top church officials have said it's up to bishops to encourage people to follow local public health guidelines.

In mid-August, they went so far as to release a statement calling on members to get the vaccine, which they described as “safe and effective.”

Among other denominations in the U.S., faith leaders have varied widely in how they address the issues of vaccinations and mask wearing. To a large extent, there has been vocal support for getting vaccinated — including from top leadership of conservative bodies such as the Southern Baptist Convention and the U.S. Conference of Catholic Bishops.

However, some Catholic prelates and evangelical pastors have been sharply critical of the the vaccine campaign and masking mandates, and others have shied away from addressing those issues for fear of angering some congregation members.

An August AP-NORC poll found that among white evangelicals, 51% are at least somewhat confident in the vaccines to be effective against variants, compared with 73% of Catholics, 66% of white mainline Protestants such as Presbyterians and Lutherans, 65% of nonwhite Protestants and 67% of the religiously unaffiliated.

Some Latter-day Saints have accused those who promote anti-vaccine rhetoric of apostasy, a term that is associated with wickedness and describes when individuals turn away from church principles.

Kristen Chevrier, co-founder of a Utah-based health freedom group that has advocated against vaccines, said the church should not be involved in health choices, and she worries people are being discriminated against based on their vaccine status.

Chevrier, who is a member of the faith, said she rejects the idea that people who are anti-vaccine are apostates. She cited the church’s history of encouraging members to seek their own personal revelations with God.

“How can we say that there’s a blanket statement that applies to everyone regardless of their personal revelation,” said Chevrier, who’s based in American Fork, about 30 miles (50 kilometers) south of Salt Lake City.

Many members have voiced concerns on social media that pro-mask and pro-vaccine sentiments aren’t shared by all regional church leadership, with some describing their experiences as “bishop roulette.”

Unmasked bishops at an Idaho church read the statement from top church officials to the congregation, but only a few chose to start wearing masks.

One member, Marie Johnson, said she has been disappointed that so many in her community have heeded misinformation on social media rather than church leadership’s continued calls for vaccination.

“You can find something on the internet to support any position you want to take,” said Johnson. “Why would you choose the side that doesn’t include your faith leader?”

But some churches began resuming masking practices even before the leaders' statement.

One Salt Lake City church has been encouraging vulnerable people to participate in meetings virtually and sent a message to congregants in early August recommending that everyone wear masks and get the vaccine.

“Our faith leaders have been so consistent from the very beginning,” said Søren Simonsen, of Salt Lake City. “And to hear people say, ‘This is a hoax, it doesn’t matter, it’s not affecting us,’ when millions of people have died, it’s heartbreaking.”

___

Eppolito is a corps member for the Associated Press/Report for America Statehouse News Initiative. Report for America is a nonprofit national service program that places journalists in local newsrooms to report on undercovered issues.

Sophia Eppolito, The Associated Press

‘Stop prescribing hydroxychloroquine for COVID-19’


New randomized data more conclusive

Peer-Reviewed Publication

FLORIDA ATLANTIC UNIVERSIT

‘Stop Prescribing Hydroxychloroquine for COVID-19’ 

IMAGE: IN 2021, IN THE U.S. ALONE, THERE HAVE BEEN MORE THAN 560,000 PRESCRIPTIONS OF HYDROXYCHLOROQUINE. LAST YEAR, THE 890,000 PRESCRIPTIONS WERE NINE-FOLD GREATER THAN THE PREVIOUS YEARS. view more 

CREDIT: FLORIDA ATLANTIC UNIVERSITY/GETTY IMAGES

In 2021, in the United States alone, there have been more than 560,000 prescriptions of hydroxychloroquine for the prevention, post-exposure and treatment of COVID-19. Since the onset in February 2020, the U.S. has been the epicenter of the pandemic and remains the world leader in cases and deaths. Last year, the 890,000 prescriptions for hydroxychloroquine were nine-fold greater than the previous years, leading to major shortages for the approved indications of autoimmune disease predominantly in younger women.     

In a commentary published in The American Journal of Medicine, researchers from Florida Atlantic University’s Schmidt College of Medicine and collaborators review the recent major randomized, double-blind placebo-controlled trials and present an updated meta-analysis of hydroxychloroquine in post-exposure prophylaxis as well as in hospitalized patients. Last year, these same researchers issued a plea for a moratorium on prescription of hydroxychloroquine in prevention or treatment pending the outcome of ongoing randomized trials. 

“The updated randomized evidence provides even stronger support for the halt on prescribing hydroxychloroquine in the prevention or treatment of COVID-19,” said Charles H. Hennekens, M.D., Dr.PH, senior author, the first Sir Richard Doll professor and senior academic advisor in FAU’s Schmidt College of Medicine.

The authors say that in addition to a lack of significant benefit, the new randomized evidence shows some suggestion of harm. They explain that the prior reassuring safety profile of hydroxychloroquine is applicable to patients with lupus and rheumatoid arthritis, both of which are of greater prevalence in younger and middle-age women, whose risks of fatal heart outcomes due to hydroxychloroquine are reassuringly very low.

In contrast, the risks of hydroxychloroquine for patients with COVID-19 are significantly higher because fatal cardiovascular complications due to these drugs are so much higher in older patients and those with existing heart disease or its risk factors, both of whom are more predominant in men. 

“Premature and avoidable deaths will continue to occur if people take hydroxychloroquine and avoid the public health strategies of proven benefit, which include vaccinations and masking,” added Hennekens. 

Co-authors are Manas Rane, M.D., a preventive cardiology fellow at the Harvard Medical School and Boston VA System and a former FAU internal medicine resident; Joshua J. Solano, M.D., an assistant professor of emergency medicine; Scott M. Alter, M.D., M.B.A., an associate professor of emergency medicine; and Richard D. Shih, M.D., professor of emergency medicine; all within the Schmidt College of Medicine; Dennis G. Maki, M.D., Ovid O. Meyer Professor of Medicine, and David L. DeMets, Ph.D., Max Halperin Professor of Biostatistics, emeritus, and former founding chair of the Department of Biostatistics and Medical Informatics, both with the University of Wisconsin School of Medicine and Public Health; Heather Johnson, M.D., preventive cardiologist at Lynn Women’s Health and Wellness Institute, Boca Raton Regional Hospital/Baptist Health South Florida and an adjunct professor at the University of Wisconsin School of Medicine and Public Health; and Shiv Krishnaswamy, a fourth-year medical student, FAU Schmidt College of Medicine.

Hennekens and Maki have been collaborators since 1969, when they served as lieutenant commanders in the U.S. Public Health Service as epidemic intelligence service officers with the U.S. Centers for Disease Control and Prevention. Hennekens, Maki and Johnson also collaborated on a recently published commentary emphasizing the already alarming racial inequalities in mortality from COVID-19, which are only likely to increase further until the vaccines are distributed equitably. 

- FAU -

About the Charles E. Schmidt College of Medicine:

FAU’s Charles E. Schmidt College of Medicine is one of approximately 157 accredited medical schools in the U.S. The college was launched in 2010, when the Florida Board of Governors made a landmark decision authorizing FAU to award the M.D. degree. After receiving approval from the Florida legislature and the governor, it became the 134th allopathic medical school in North America. With more than 70 full and part-time faculty and more than 1,300 affiliate faculty, the college matriculates 64 medical students each year and has been nationally recognized for its innovative curriculum. To further FAU’s commitment to increase much needed medical residency positions in Palm Beach County and to ensure that the region will continue to have an adequate and well-trained physician workforce, the FAU Charles E. Schmidt College of Medicine Consortium for Graduate Medical Education (GME) was formed in fall 2011 with five leading hospitals in Palm Beach County. The Consortium currently has five Accreditation Council for Graduate Medical Education (ACGME) accredited residencies including internal medicine, surgery, emergency medicine, psychiatry, and neurology.

About Florida Atlantic University:
Florida Atlantic University, established in 1961, officially opened its doors in 1964 as the fifth public university in Florida. Today, the University serves more than 30,000 undergraduate and graduate students across six campuses located along the southeast Florida coast. In recent years, the University has doubled its research expenditures and outpaced its peers in student achievement rates. Through the coexistence of access and excellence, FAU embodies an innovative model where traditional achievement gaps vanish. FAU is designated a Hispanic-serving institution, ranked as a top public university by U.S. News & World Report and a High Research Activity institution by the Carnegie Foundation for the Advancement of Teaching. For more information, visit www.fau.edu.

 

Disclaimer: AAAS and Eure

Racial/ethnic differences in COVID-19 vaccine hesitancy among health care workers in 2 large academic hospitals

JAMA Network Open

Peer-Reviewed Publication

JAMA NETWORK

What The Study Did: This survey study of almost 11,000 health care workers (HCWs) from two academic hospitals found that, compared with white HCWs, vaccine hesitancy was increased nearly five-fold among Black HCWs, two-fold among Hispanic or Latino HCWs, and by nearly 50% among Asian HCWs and HCWs who were members of other racial/ethnic groups.

Authors: Florence M. Momplaisir M.D., M.S.H.P., of the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2021.21931)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2021.23512?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=083021

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

Organ transplants fell by a third worldwide during first wave of Covid-19 pandemic, new study shows


The number of solid organ transplants performed during the first wave of Covid-19 in 2020 plunged by 31% compared to the previous year

Peer-Reviewed Publication

EMOTIVE

(Milan, Tuesday 31 August, 2021) The number of solid organ transplants performed during the first wave of Covid-19 in 2020 plunged by 31% compared to the previous year, according to a new global study presented today at the European Society for Organ Transplantation (ESOT) Congress 20211.

According to modelling calculations, the slowdown in transplants resulted in more than 48,000 years of patient life loss.

The research leveraged international data from 22 countries across four continents and revealed major variations in the response of transplant programmes to the Covid-19 pandemic, with transplant activity dropping by more than 90 per cent in some countries.

Kidney transplantation showed the largest reduction across nearly all countries during 2020 compared to 2019, with the study finding a decrease in living donor kidney (-40 per cent) and liver (-33 per cent) transplants. For deceased donor transplants, there was a reduction in kidney (-12 per cent), liver (-9 per cent), lung (-17 per cent) and heart (-5 per cent) transplants.

The research, published today in the Lancet Public Health, highlighted how some countries managed to sustain the rate of transplant procedures whilst others experienced serious reductions in the number of transplants compared to the previous year and, in some areas, living donor kidney and liver transplantation ceased completely. Overall, there was a strong temporal association between increased Covid-19 infection rate and reductions in deceased and living solid organ transplants.

Dr Olivier Aubert, Assistant Professor at the Paris Translational Research Centre for Organ Transplantation and lead author of the study, commented, “The first wave of Covid-19 had a devastating impact on the number of transplants across many countries, affecting patient waiting lists and regrettably leading to a substantial loss of life.” 

Professor Alexandre Loupy, head of the Paris Translational Research Center for Organ Transplantation and last author of the study, furthered, “Living donor transplantation, which reduced more substantially, requires significant resources and planning compared to deceased donor transplantation. This is extremely difficult during a pandemic when resources are stretched and staff redeployed. There are also major ethical concerns for the wellbeing and safety of the donor.”

“It’s clear that there are many indirect deaths associated with Covid-19 and our study confirms that the pandemic has far-reaching consequences on many medical specialties.” added Prof. Loupy.

The estimated numbers of life-years lost were 37,664 years for patients waitlisted for a kidney, 7,370 for a liver, 1,799 years for a lung, and 1,406 for a heart, corresponding to a total 48,239 life-years lost.

Dr Aubert added, “Beyond the near universal reduction in transplant activity, certain countries and regions managed to carry-out procedures despite major challenges presented by the pandemic. These findings warrant further analysis on a regional, national and global level to understand why reductions did or did not occur.”

“Understanding how different countries and healthcare systems responded to Covid-19-related challenges can facilitate improved pandemic preparedness and how to safely maintain transplant programmes to provide life-saving procedures for patients.”

To facilitate understanding of the temporal trends and consequences of the pandemic on worldwide, national, and regional solid organ transplant activities for researchers, clinicians, and public health authorities, the authors created an open-access dashboard that presents data interactively for solid organ transplant activities and COVID-19 cases.

 

Change in the overall observed solid organ transplant counts between 2020 from the date of the first 100 reported cumulative COVID-19 cases until the end of follow-up (latest date of available data through December 31st 2020) and the same period of time in 2019, by country and organ

Nation

Overall

Kidney

Liver

Lung

Heart

Argentina, N. (%)*

-564 (-60·91%)

-429 (-64·32%)

-107 (-56·61%)

-8 (-47·06%)

-20 (-37·74%)

Austria, N. (%)

-56 (-10·22%)

-53 (-17·91%)

6 (5·08%)

0 (0%)

-9 (-16·36%)

Belgium, N. (%)

-166 (-22·46%)

-78 (-22·67%)

-49 (-20·68%)

-16 (-17·39%)

-23 (-34·85%)

Brazil, N. (%)

-2174 (-28·9%)

-1735 (-32·89%)

-307 (-16·51%)

-50 (-56·82%)

-82 (-27·42%)

Canada, N. (%)

-227 (-9·86%)

-229 (-16·29%)

5 (1·09%)

4 (1·47%)

-7 (-4·24%)

Chile, N. (%)*

-47 (-54·02%)

-23 (-46·94%)

-10 (-45·45%)

-6 (-85·71%)

-8 (-88·89%)

Croatia, N. (%)

-85 (-37·28%)

-35 (-36·84%)

-34 (-33·01%)

0 (NaN%)

-16 (-53·33%)

Finland, N. (%)

-48 (-13·68%)

-38 (-15·38%)

5 (9·26%)

-5 (-20·83%)

-10 (-38·46%)

France, N. (%)

-1410 (-28·96%)

-1041 (-34·28%)

-219 (-19·04%)

-101 (-31·27%)

-49 (-13·65%)

Germany, N. (%)

-328 (-10·53%)

-236 (-13·15%)

-46 (-6·5%)

-36 (-11·32%)

-10 (-3·4%)

Greece, N. (%)*

-11 (-12·22%)

-6 (-8·7%)

-2 (-14·29%)

1 (Inf%)†

-4 (-57·14%)

Hungary, N. (%)

-132 (-37·29%)

-79 (-37·26%)

-27 (-39·71%)

0 (0%)

-26 (-43·33%)

Italy, N. (%)

-525 (-16·18%)

-296 (-16·17%)

-162 (-15·25%)

-40 (-30·08%)

-27 (-12·27%)

Japan, N. (%)

-1413 (-66·71%)

-1112 (-69·63%)

-257 (-67·45%)

-18 (-26·47%)

-26 (-36·11%)

Netherlands, N. (%)

-187 (-17·64%)

-166 (-21·15%)

-7 (-4·46%)

-19 (-21·35%)

5 (17·24%)

Norway, N. (%)

-24 (-7·12%)

-6 (-2·99%)

3 (4·11%)

-6 (-22·22%)

-15 (-41·67%)

Portugal, N. (%)

-156 (-24·19%)

-67 (-19·76%)

-75 (-33·63%)

-10 (-15·62%)

-4 (-21·05%)

Slovenia, N. (%)

7 (8·43%)

7 (21·21%)

-2 (-9·52%)

6 (66·67%)

-4 (-20%)

Spain, N. (%)

-1033 (-24·02%)

-745 (-26·89%)

-176 (-18·6%)

-88 (-26·19%)

-24 (-9·68%)

Switzerland, N. (%)

-6 (-1·34%)

-7 (-2·69%)

-15 (-11·63%)

6 (20%)

10 (34·48%)

United Kingdom, N. (%)

-1298 (-31·31%)

-1076 (-35·54%)

-147 (-17·95%)

-69 (-47·92%)

-6 (-3·87%)

United States, N. (%)

-1370 (-4·13%)

-1110 (-5·44%)

-91 (-1·23%)

-237 (-10·18%)

68 (2·25%)

Overall, N. (%)

-11253 (-15·92%)

-8560 (-19·14%)

-1714 (-10·57%)

-692 (-15·51%)

-287 (-5·44%)

 

*Argentina, Chile, and Greece follow-up ended earlier than other countries due to data availability. Argentina ends on 2020-08-18, Chile end on 2020-05-27, and Greece ends on 2020-07-28. The remaining countries include through December 31st 2020. †There were no lung transplants in Greece in 2019.

 

ENDS

Notes to Editors:

A reference to the ESOT Congress 2021 must be included when communicating the information within this press release.

Please note that the open-access dashboard providing data for solid organ transplant activities and COVID-19 cases will go live during the Congress. To access the dashboard, please visit: www.covidtransplants.org

For further information, to access the full paper or to request an expert interview, please contact Luke Paskins or Sean Deans at press@esot.org or call +44 (0) 208 154 6396.

About the Expert:

Dr Olivier Aubert is an assistant professor and nephrologist at the Necker Hospital, Paris, France. He also has a PhD in biostatistics from the Paris Translational Research Centre for Organ Transplantation.

Prof. Alexandre Loupy is a professor and nephrologist at the Necker Hospital, Paris, France. He is also the head of the Paris Translational Research Centre for Organ Transplantation.

About ESOT:

The European Society for Organ Transplantation (ESOT) was founded over 30 years ago and is dedicated to the pursuit of excellence in organ transplantation. Facilitating a wealth of international clinical trials and research collaborations over the years, ESOT remains committed to its primary aim of improving patient outcomes in transplantation. With a community of over 8,000 affiliates from around the world, ESOT is an influential international organisation and the facilitator of the biennial congress which hosts approximately 3,500 experts who come to meet to explore and discuss the latest scientific research. For more information visit: https://esot.org/

About the ESOT Congress 2021:

The ESOT Congress 2021, taking place in-person and on-line and in Milan, Italy, features the latest research and innovation from the most prominent scientists and physicians in the field of organ transplantation. For more information visit:          https://www.esotcongress.org/

References:

  1. COVID-19 Pandemic Consequences On Worldwide Organ Transplantation: a population-based study. Presented at the ESOT Congress 2021.

 

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Fighting vaccine hesitancy: Family physicians tap into digital communication tools to better inform patients

Grant and Award Announcement

UNIVERSITY OF OTTAWA

University of Ottawa logo 

IMAGE: UNIVERSITY OF OTTAWA COLOR LOGO view more 

CREDIT: UNIVERSITY OF OTTAWA

Family physicians across the country are harnessing the power of digital communication to tackle vaccine hesitancy, relying on text and email to share evidence-based resources regarding COVID-19 vaccines with patients who are hesitating or facing barriers to vaccination.

Physicians from the University of Ottawa’s Department of Family Medicine and the Institut du Savoir at the Montfort Hospital have partnered with the Eastern Ontario Health Unit to support family physician’s bid to bolster COVID-19 vaccine uptake. The Public Health Agency of Canada is funding this $450,000 project, which will involve 300 family physicians and nurse practitioners.

The goal of the pan-Canadian randomized controlled trial is to identify segments of the patient population with common reasons for vaccine hesitancy or lack of access, by age, language, education level, rurality, gender, and ethnicity. Primary care providers can then provide these groups with appropriately tailored digital information by e-mail and text message. 

“We want to help family physicians or primary care practitioners to learn about patients’ perspectives and survey if they are vaccinated or not. And, if not, why?” says Dr. Sharon Johnston, Associate Professor in the Faculty of Medicine and an Investigator at the Institut du Savoir Montfort and Bruyère Research Institute.

“By understanding the concerns and barriers faced by this subgroup, we can amass data that can guide us on communicating more effectively. We will be able to identify groups of patients who share similar reasons for being unvaccinated and common features, and we can create short messages to share reliable and relevant resources on COVID-19 vaccines to help them with their decision-making,” adds Dr. Johnston.

Family practitioners will use the Canadian Primary Care Information Network (CPIN), an automated patient engagement system for primary care practices, to rapidly inform patients about new procedures for clinic visits, availability of vaccines from COVID-19 to flu, or patient education materials for managing conditions like back pain. CPIN also offers a reliable and confidential system to collect anonymous feedback on patients’ experiences by including a link to a short survey at the end of each message.

“This tool will help primary care communicate better with patients in an effective way, reaching their patients more easily,” Johnston says. “By learning what patients prefer – such as a virtual visit or an in-person one, or what factors led to their hesitancy to be vaccinated – we can try to develop a tool that will lessen the workload, share good information and help our patients to make well informed decisions when it comes to their health.”

Primary care practitioners often see patients from within a 100-kilometre radius, making this innovative research project a means of delivering information to patients from a physician who may not be familiar with their home area and the services available to them.