Showing posts sorted by relevance for query PSYCHEDELIC . Sort by date Show all posts
Showing posts sorted by relevance for query PSYCHEDELIC . Sort by date Show all posts

Wednesday, December 28, 2022

Psychedelic chaplains: In clinical trials, a new form of spiritual guide emerges

Spiritual care practitioners are being trained to support patients undergoing psychedelic therapy in clinical trials and decriminalized settings.

Photo by Raimond Klavins/Unsplash/Creative Commons

(RNS) — Moana Meadow was 22 when her grandmother died in a hospital room, sitting up, eyes open, gripping the hands of her family members.

“Her spirit left her body like that. In an instant,” she said. “I wasn’t religious, but her spirit felt like it was hovering in the room for 15 minutes. There was this energy, pulsating. I’ve never experienced anything like that before.”

The event, though painful, left an imprint on Meadow and convinced her to pursue the life of an interfaith chaplain so she could accompany others who were dying.

Now, the hospice chaplain is interested in helping people through other transitions — the perceptual changes brought on by psychedelic drugs. “Being with people in altered states of consciousness” can be similar to pivotal moments like marriage, childbirth or death, Meadow said, and she is on a mission to bridge chaplaincy and the work of accompanying people who are under the influence of psychedelics.

“Psychedelic experiences, particularly at higher dosages, can feel like dying,” said Sam Shonkoff, assistant professor of Jewish studies at Graduate Theological Union in Berkeley, California. “One can feel as if they’re being born. One can feel a sense of existential rupture. To have a chaplain there, who maybe has a lot of experience with sitting with people who are facing death, that can be really applicable to accompanying people who are having these experiences with psychedelics.”

Since the mid-aughts, a tidal wave of scientific research on psychedelics has flooded academic journals with evidence that these substances may be able to provide relief for everything from smoking addiction to anxiety and depression. These benefits arise at least in part, some psychedelic researchers argue, from the mystical or spiritual encounters the drugs can induce.

Moana Meadow. Photo by Julia Maryanska

Moana Meadow. Photo by Julia Maryanska

“As the scientific research on spiritual experience with psychedelics has started to come out so strongly,” said Meadow, “I think people are beginning to understand or admit the importance of religious training and knowledgeability in psychedelic work.” 

As a result, academic institutions across the U.S. are launching training programs in which spiritual practitioners can become qualified psychedelic facilitators, paving the way for a new field of psychedelic chaplaincy.

Current opportunities for these roles are limited in the U.S., as the use of the drugs themselves is considered experimental. Ketamine, a powerful but relatively safe anesthetic, is legal for medical use, and some health care chaplains act as facilitators for ketamine-assisted therapy, which has shown promise for relieving depression. As researchers have begun conducting clinical trials for psychedelic treatments, too, they are recruiting chaplains.

The Rev. Caroline Peacock, an ordained Episcopal priest and a chaplain for Emory Healthcare in Atlanta, will be serving as a spiritual health clinician in a clinical trial assessing whether psilocybin might help treat anxiety, depression and chronic pain experienced by cancer survivors.

In these settings, psychedelic chaplains are asked to provide spiritual care for clients before, during and after a psychedelic dose, aiding them as they work to elicit meaning from the experience. 

“Some of the questions psychedelic chaplaincy is bringing to the table are some of the oldest questions of all,” said Shonkoff, who pointed out that Indigenous shamans, medicine women and elders have been doing this work for centuries. But the presence of a psychedelic chaplain on these scientific teams is something new.

Jamie Beachy, left, with Rick Doblin, the founder of MAPS, at the MAPS MDMA training center in Red Feather Lakes, Colorado, in May 2019. Courtesy photo

Jamie Beachy, left, with Rick Doblin, the founder of MAPS, at the MAPS MDMA training center in Red Feather Lakes, Colorado, in May 2019. Courtesy photo

Jamie Beachy, a chaplain by training and the director of education for the Center for Psychedelic Studies at Naropa University in Boulder, Colorado, joined a study looking at MDMA, also known as the recreational drug ecstasy, as an aid for treatment-resistant post-traumatic stress disorder. The research, led by the Multidisciplinary Association for Psychedelic Studies, shows that 67% of participants taking MDMA no longer meet the criteria for PTSD, compared with 32% of participants in the placebo group.

“I have been compelled to see how people are able to move through traumas in a way that I wasn’t seeing in the hospital or the trauma settings I was working in,” said Beachy, a former health care chaplain.

Beachy said chaplains, who are often “present to traumas unfolding in real time,” can help clients navigate events that could disrupt their existing belief systems, something psychedelic therapy patients may face. “In one of the Johns Hopkins studies of DMT — another powerful psychedelic — people that went into the study reporting that they were atheists apparently came out of the study feeling less connected with atheism,” Beachy told RNS.

Beachy is developing a degree concentration in psychedelic care for the Master of Divinity program at Naropa, which already offers a psychedelic-assisted therapies certificate for professionals. 

Meadow, meanwhile, is program director of a new psychedelic facilitator certification program at the UC Berkeley Center for the Science of Psychedelics, aimed at people who are already professionals in spiritual care and health care. Graduates may be eligible to apply for a Psilocybin Facilitator License in Oregon or Colorado, which recently decriminalized psilocybin. Religious professionals would be able to act as psychedelic chaplains in health care or research settings where regulations permit.

“At the program that I’m running at UC Berkeley, there’s a clear value on the spiritual aspects of psychedelic work,” said Meadow. “So we’re attracting chaplains to our training program and promoting their expertise in this field as well.”

Sam Shonkoff. Courtesy photo

Sam Shonkoff. Courtesy photo

At both UC Berkeley and Naropa, the programs emphasize the Indigenous roots of many psychedelic practices, which Shonkoff celebrates. “There has been a tendency in this burgeoning field of psychedelic study to try to talk about the so-called mystical aspects of psychedelics without reference to particular cultural and spiritual traditions that have used these substances,” he said.

As states decriminalize psychedelics, said Ron Cole-Turner, professor emeritus at Pittsburgh Theological Seminary who often writes on theology and psychedelics, recreational, ceremonial and religious uses for psychedelics will likely expand. 

“Give us a decade, and I can’t imagine we won’t have well-established opportunities in multiple parts of the United States, definitely Oregon, very likely Colorado and other places … where there will be open, out, legal and reasonably well-supervised and therefore safe pathways for people who just simply want to see if this enriches their spiritual lives,” he told Religion News Service.

Chaplains will be necessary for these grassroots uses as well, said Celina De Leon, founder and director of the Circle of Sacred Nature 501(c)3 Church, based in California’s Bay Area, for which taking ayahuasca is a “sacramental practice” that is a “fundamental expression of our religious beliefs,” De Leon told RNS.



While De Leon views these substances as having “beautiful potential,” she readily acknowledges that not all psychedelic experiences are positive. “Sometimes psychedelic experiences can be very challenging, and people can really benefit from having support in their meaning making process,” she said. “I think chaplains can be very well suited for that on a community level, outside of clinical contexts.”

Some people, De Leon adds, have destabilizing encounters — the colloquial “bad trip” — and because of a person’s vulnerability during psychedelic therapy, there can also be safety risks.

Currently, there’s no standard pathway for becoming a psychedelic chaplain. Beachy would like to see nondegree programs like Naropa’s be complemented by a national advanced certification for psychedelic chaplains, similar to those that certify chaplains in palliative care or ethics consultation.

The first wave of psychedelic chaplains is already here, however, reconnecting the link between psychedelics and religion, as science reconnects the link between the drugs and health.

“Psychedelics have traditionally been medicines that were used for spiritual growth, healing and prayer,” said Meadow. “If we’re not thinking about them that way, we are missing something very important.”


Tuesday, April 22, 2025

 

Predicting long-term psychedelic side-effects



Schizotypal traits may not be caused by taking LSD or magic mushrooms




PNAS Nexus





Psychedelic drugs are seeing a surge of interest from mainstream medicine, and initial results suggest that psychedelic-therapy can be a safe and effective treatment for some mental health conditions. However, the side-effect profile is still incompletely understood. In particular, the use of psychedelics has been posited to carry a risk of triggering latent psychotic disorders or persistent visual hallucination, known as Hallucinogen Persisting Perception Disorder (HPPD). In order to better understand the prevalence and risk factors of such side-effects, Katie Zhou and colleagues surveyed 654 people online who were planning to take psychedelics through their own initiative. Of those, 315 people were resurveyed two weeks after their experience and 212 people were resurveyed again four weeks after their experience. The sample was 74% male, and 77% university educated. About one third had been diagnosed with at least one psychiatric condition. The authors found a weak correlation between lifetime psychedelic use and both delusional ideation and magical thinking. However, on average, delusional ideation was slightly reduced one month after psychedelic use. These results suggest that schizotypal traits may not be caused by taking LSD or magic mushrooms, in keeping with the principle that correlation does not imply causation. About a third of individuals surveyed at the four-week mark did have some lingering hallucinatory sensory experiences, such as intensified colors and afterimages. However, the majority of those who experienced this did not report being distressed by it. The strongest predictors of persistent visual aftereffects were the personality trait absorption—the tendency to be easily immersed in sensory or imaginative experiences—and younger age. This corroborates previous findings showing that young people and adolescents may be at a particular risk of HPPD. According to the authors, empirical scrutiny of the potential risks of psychedelics should accompany changes in policy and access to psychedelic drugs.

Monday, January 16, 2023

Alberta’s new policy on psychedelic drug treatment for mental illness: Will Canada lead the psychedelic renaissance?


Erika Dyck, 
Professor and Canada Research Chair in the History of Health & Social Justice,
 University of Saskatchewan
THE CONVERSATION
Sun, January 15, 2023 

Psychedelics are being held up as a potential solution to the growing need for mental health treatment. But, magic mushrooms are not magic bullets.
 (AP Photo/Peter Dejong)

Patients in Alberta will now be able to legally consider adding psychedelic-assisted therapy to the list of treatment options available for mental illnesses.

Alberta psychiatrists and policymakers suggest that they are getting ahead of the curve by creating regulations to ensure the safe use of these hallucinogenic substances in a therapeutically supported environment. As of Jan. 16, the option is available only through registered and licensed psychiatrists in the province.

Alberta’s new policy may set a precedent that moves Canadians one step closer to accepting psychedelics as medicinal substances, but historically these drugs were widely sought out for recreational and non-clinical purposes. And, if cannabis has taught us anything, medicalizing may simply be a short stop before decriminalizing and commercializing.

Psychedelic drugs — including LSD, psilocybin (magic mushrooms), MDMA (ecstasy) and DMT (ayahuasca) — are criminalized substances in most jurisdictions around the world, but some people are suggesting it is time to re-imagine them as medicines. A few places are even considering decriminalizing psychedelics altogether, claiming that naturally occurring plants like mushrooms, even “magic” ones, should not be subject to legal restrictions.

In the wake of cannabis reforms, it appears that psychedelics may be the next target in the dismantling of the war on drugs. Canada made bold strides internationally with its widespread cannabis decriminalization, but are Canadians ready to lead the psychedelic renaissance?

Early psychedelic research


There is some precedent for taking the lead. In the 1950s and ‘60s, an earlier generation of researchers pioneered the first wave of psychedelic science, including Canadian-based psychiatrists who coined the word psychedelic and made headlines for dramatic breakthroughs using LSD to treat alcoholism.

Vancouver-based therapists also used LSD and psilocybin mushrooms to treat depression and homosexuality. While homosexuality was considered both illegal and a mental disorder until later in the 1970s, psychedelic therapists pushed back against these labels as patients treated for same-sex attraction more often experienced feelings of acceptance — reactions that aligned this particular approach in Vancouver with the gay rights movement.


Despite positive reports of clinical benefits, by the end of the 1960s psychedelics had earned a reputation for recreational use and clinical abuse. And, there was good reason to draw these connections, as psychedelic drugs had moved from pharmaceutical experimentation into mainstream culture, and some researchers had come under scrutiny for unethical practices.

Regulation and criminalization

Most legal psychedelics ground to a halt in the 1970s with a set of regulatory prohibitions and cultural backlash. In public health reports since the 1970s, psychedelics have been described as objects of unethical research, recreational abuse and personal risk including injury and even death.

Underground chemists and consumers tried to combat this image, suggesting that psychedelics provided intellectual and spiritual insights and enhanced creativity.

Most jurisdictions around the world criminalized psychedelics, whether for clinical research or personal experimentation. Indigenous and non-western uses of hallucinogenic plants of course stretch back even further in history, and these too came under legal scrutiny through a combination of colonial pressures to assimilate and a looming war on drugs that did not distinguish between religious practices and drug-seeking behaviours.

The return of psychedelics


At the moment, the next generation of scientific research on psychedelics still lags behind the popular enthusiasm that has catapulted these substances into the mainstream. 
(AP Photo/Peter Dejong)

In the last decade, regulations prohibiting psychedelics have started relaxing. The U.S. Food and Drug Administration has designated breakthrough therapy status to MDMA and psilocybin, based on their performance in clinical trials with post-traumatic stress disorder (PTSD) and treatment-resistant depression, respectively.

Health Canada has provided exemptions for the use of psilocybin for patients with end-of-life anxiety, and has started approving suppliers and therapists interested in working with psychedelic-assisted psychotherapy. Training programs for psychedelic therapists are popping up across Canada, perhaps anticipating a change in regulation and the current lack of trained professionals ready to deliver psychedelic medicine.

At the moment, the next generation of scientific research on psychedelics still lags behind the popular enthusiasm that has catapulted these substances into the mainstream. Celebrity testimonials and compelling patient accounts are competing for our attention.

Meanwhile, the growing burden of mental illness continues to overwhelm our health-care systems. Psychedelics are being held up as a potential solution. But, magic mushrooms are not magic bullets.
Beyond the medical marketplace

Historically hallucinogenic substances have defied simple categorization as medicines, spiritual enhancers, toxins, sacred substances, rave drugs, etc. Whether or not Health Canada, or the province of Alberta, reclassifies psychedelics as a bona fide therapeutic option, these psychoactive substances will continue to attract consumers outside of clinical settings.

Canada has an opportunity to take the lead once more in this so-called psychedelic renaissance. But, it might be our chance to invest in more sustainable solutions to harm reduction and ways of including Indigenous perspectives, rather than racing to push psychedelics into the medical marketplace.

Indigenous approaches to sacred plants are not only about consuming substances, but involve preparation, intention and integration, often structured in ritualistic settings that are as much about spiritual health as physical or mental health.

This cosmology and approach does not easily fit under the Canada Health Act, nor is it obvious who should be responsible for regulating or administering rituals that sit outside of our health-care system. These differences in how we might imagine the value of psychedelics is an opportunity to rethink the place of Indigenous knowledge in health systems.

We are well positioned to take a sober approach to the psychedelic hype, which has been driven in large part by financial interests, and consider what aspects of the psychedelic experience we want to preserve.

Now may be a good time to reinvest in our public institutions to ensure that psychedelics don’t simply become another pharmaceutical option that profits private investors. Instead, we have an opportunity with psychedelics to rethink how a war on drugs has harmed individuals and communities and how we might want to build a better relationship with pharmaceuticals.

This article is republished from The Conversation, an independent nonprofit news site dedicated to sharing ideas from academic experts. It was written by: Erika Dyck, University of Saskatchewan

Read more:

The real promise of LSD, MDMA and mushrooms for medical science

Psychedelic experiences disrupt routine thinking — and so has the coronavirus pandemic

Erika Dyck receives funding from Social Sciences and Humanities Research Council. She is a board member of the US not-for-profit Chacruna Institute for Psychedelic Plant Medicines.

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Tuesday, December 31, 2024


Medical researcher explores economic impact of psychedelic therapy implementation



Emory University Fayzan Rab discusses groundbreaking research in exclusive Genomic Press Interview



Genomic Press

Fayzan Rab 

image: 

Fayzan Rab, MD Candidate, Emory University, USA.

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Credit: Fayzan Rab




ATLANTA, Georgia, USA, 31 December 2024 - In a comprehensive Genomic Press Interview, Emory University MD candidate Fayzan Rab shares insights into his pioneering research on the economic and public health implications of psychedelic therapy implementation. Rab's work at the Emory Center for Psychedelics and Spirituality bridges the gap between clinical research and real-world healthcare delivery systems.

"It would be a fool's errand to say that psychedelic therapies alone would change that," says Rab, discussing mental healthcare challenges. "Treating mental illness will require changes within clinical practice but also investments into social safety nets, re-employment opportunities, and affordable housing."

Rab brings a unique perspective to psychedelic research, having previously led product development at Google and Mindstrong Health before pursuing medicine. His recent publication in Psychedelics, co-authored with Raison and Marseille, provides the first comprehensive estimate of potential patient demand for psilocybin therapy in depression treatment.

The research tackles critical implementation questions often overlooked in psychedelic science. While many studies focus on clinical trials, Rab investigates broader systemic challenges: healthcare accessibility, cultural inclusion, and economic viability. His work particularly emphasizes the importance of making these innovative treatments accessible to traditionally underserved communities.

"My hope in psychedelic science is that we get to integrate those questions early on while psychedelic therapies are in their infancy," Rab explains. "By addressing and planning for them now, I believe these therapies could reach and become more accessible to those generally excluded from treatment innovations."

Beyond traditional mental health applications, Rab has an interest in expanding the scope of psychedelic research to new populations including healthcare workers, cancer patients, and post-partum mothers and those with chronic pain. His work emphasizes the importance of community partnerships in developing research questions, particularly in his studies of Muslim communities' perspectives on psychedelic therapies.

The Genomic Press Interview offers unique insights into Rab's methodology and vision. His research group operates on two fundamental principles: maintaining narrow focus while seeking broader applications, and valuing progress over perfection. This approach has enabled meaningful contributions to the field while maintaining scientific rigor.

Dr. Charles Raison, Director of Research at the Emory Center for Psychedelics and Spirituality, notes: "Rab's research addresses crucial questions about implementation and accessibility that will shape the future of psychedelic medicine."

Fayzan Rab’s Genomic Press interview is part of a larger series that highlights the people behind today’s most influential scientific ideas. Each interview in the series offers a blend of cutting-edge research and personal reflections, providing readers with a comprehensive view of the scientists shaping the future. By combining a focus on professional achievements with personal insights, this interview style invites a richer narrative that both engages and educates readers. This format provides an ideal starting point for profiles that delve into the scientist’s impact on the field, while also touching on broader human themes. More information on the research leaders and research rising stars featured by Genomic Press can be found in our publication website: https://genomicpress.kglmeridian.com/.

The full Genomic Press Interview, titled “Fayzan Rab: What are the economic and public health implications of psychedelic therapies?,” is available on 24 December 2024 in Psychedelics, offering readers an unparalleled opportunity to explore the thoughts and experiences of one of the most influential minds in neuroscience and neurobiology of brain disorders. The article is freely available online at https://doi.org/10.61373/pp024k.0046.

About Psychedelics – Psychedelics: The Journal of Psychedelic Pharmacology (ISSN: 2997-2671) is a peer-reviewed medical research journal published by Genomic Press, New York. Psychedelics is exclusively dedicated to the latest advancements in the realm of psychedelic substances and their potential therapeutic uses. We embrace the full spectrum of research, from fundamental investigations to cutting-edge clinical studies. Psychedelics welcomes diverse perspectives and contributions, advancing the understanding of psychedelic compounds.

Tuesday, December 17, 2024

 

Attitudes toward psychedelic therapy reveal both promise and caution, new study finds



Psychedelic care facilitators express optimism about benefits while maintaining awareness of potential risks




Genomic Press

Psilocybe semilanceata 

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Psilocybe semilanceata

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Credit: Arp - This image is Image Number 6514 at Mushroom Observer, a source for mycological images.




ATLANTA, Georgia, USA, 17 December 2024 - In a comprehensive Genomic Press Interview with researchers from Emory University, a new study published today reveals complex attitudes toward psychedelic therapy, with detailed statistics showing both strong support for potential benefits and significant awareness of risks.

The research, published in the journal Psychedelics, surveyed 178 attendees at an academic conference focused on psychedelics and spiritual care. Among participants, 32 were active psychedelic therapy facilitators, of whom 87.5% reported prior personal experience with psychedelics and 62.1% had used psychedelics specifically for therapeutic purposes.

"What struck us most was the sophisticated understanding of both benefits and risks among attendees of the conference as well as psychedelic care practitioners," says Professor Roman Palitsky from Emory University's Department of Psychiatry and Behavioral Sciences, the study's corresponding author. “While 40.2% of participants agreed that psychedelics could be harmful even in therapeutic contexts, we also found strong belief in their potential benefits, particularly for specific conditions,” added Dr. Zachary Bosshardt, lead author of the study.

Dr. Jessica L. Maples-Keller, study co-author, elaborates on the findings regarding treatment approaches: "Among facilitators, we found a preference for established therapeutic frameworks, with 65.6% utilizing supportive or Rogerian psychotherapy, and many others utilizing structured approaches likes cognitive behavioral therapy (CBT). This suggests a bridge between traditional therapeutic approaches and psychedelic treatment."

"These findings tell us something important about the evolving landscape of psychedelic therapy," notes Dr. Boadie W. Dunlop, another study co-author. "We're seeing a field that's maturing beyond simple enthusiasm to develop a more nuanced understanding of both opportunities and challenges."

Dr. Deanna M. Kaplan, who contributed to the study, points out an interesting finding: "The fact that 30.7% of respondents answered 'not sure' about potential harmful effects suggests an appropriate level of professional humility about these powerful compounds. This uncertainty might actually be healthy for the field's development."

The research also highlighted important questions about the future of psychedelic therapy, particularly regarding training protocols and the integration of traditional practices with modern medical approaches.

Professor Barbara Rothbaum emphasizes the implications for clinical practice: "Our findings suggest we need to develop robust safety protocols while maintaining optimism about therapeutic potential. The high rate of personal psychedelic use among facilitators - 87.5% for any use and 62.1% for therapeutic purposes - also raises important questions about training and preparation for practitioners."

The full article, titled "Reading the crowd: attitudes toward psychedelics and psychedelic therapies among attendees at a conference" is freely available online on 17 December 2024 at Psychedelicshttps://doi.org/10.61373/pp024r.0040.

About Psychedelics - Psychedelics: The Journal of Psychedelic Pharmacology (ISSN: 2997-2671) is a peer-reviewed medical research journal published by Genomic Press, New York. Psychedelics is exclusively dedicated to the latest advancements in the realm of psychedelic substances and their potential therapeutic uses. We embrace the full spectrum of research, from fundamental investigations to cutting-edge clinical studies. Psychedelics welcomes diverse perspectives and contributions, advancing the understanding of psychedelic compounds.