Wednesday, December 06, 2023

 Climate: What is the global stocktake?

DW
23 hours ago

The first global climate progress report found the world won't meet its climate goals, amid soaring temperatures. Will countries "chart a better course" to cut planet-heating emissions at key UN climate talks?


In summer 2023, Wildfires ravaged forests around the world, including in Greece (above).
Alexandros Avramidis/REUTERS

In a year of record-breaking temperatures — both on land and in the sea — the final summary of the recent UN global stocktake report held a dire warning for the planet.

"The window of opportunity to secure a liveable and sustainable future for all is rapidly closing," said the report, the first of its kind. "The Paris Agreement has driven near-universal climate action by setting goals and sending signals to the world regarding the urgency of responding to the climate crisis. While action is proceeding, much more is needed now on all fronts."

The global stocktake, the culmination of two years of analysis by climate scientists, government officials and other experts, is a review of the world's collective progress toward meeting the 2015 Paris Agreement goal of limiting global heating. And it has shown that the world is far off track.

UN warns world off track to meeting development goals  02:48


The report stressed that the goal to limit warming to 1.5 degrees Celsius (2.7 degrees Fahrenheit) above pre-industrial levels by the end of the century was becoming increasingly unrealistic. The UN's World Meteorological Organization has said there's a two-out-of-three chance that Earth will temporarily exceed that threshold within the next five years.

In order for the world to stay at 1.5 Celsius, the report said the use of unabated coal power would have to drop by 67-82% by 2030 versus 2019 levels, and drop to almost nothing by mid-century.

The authors of the report also called for "the phaseout of unabated fossil fuels" and for more funding to support low-carbon development. It said the world needed to redirect the $450 billion (€424 billion) in annual subsidies for coal, oil and natural gas, calling for increased funding for people and places hurt by extreme weather caused by global warming.

Disappointment over first draft


Climate negotiators and world leaders are using these findings to shape discussions at the UN climate conference Dubai, with arguments around whether to "phase out" or "phase down" all fossil fuels set to dominate.



A draft text relating to the stocktake published December 1 by the UN Climate Change secretariat (just like the stocktake itself) noted with "concern" the "rapidly narrowing window" for countries to raise their ambitions on cutting emissions to limit warming to 1.5 C.

But the text still makes reference to a possible "phase-down" of oil, coal and gas. Activists, scientists and, most recently, German Chancellor Olaf Scholz have said a full phaseout of climate-wrecking fossil fuels is necessary to stop catastrophic planetary heating.

"We must now all show a firm determination to phase out fossil fuels — first and foremost coal. We can set sail for this at this climate conference," Scholz told delegates at the COP28 summit on Saturday.

In the meantime, Sultan Ahmed al-Jaber, COP28 president and head of Abu Dhabi's state-run oil company, was forced to reiterate his faith in climate science after a video showed him questioning the scientific consensus that a fossil fuel phaseout is necessary to curb global warming.

Other stumbling blocks at COP28


At climate talks in Bonn, Germany, back in June, Harjeet Singh of the Climate Action Network International told DW the thorny questions about who is responsible for planet-warming emissions — both now and in the past — and who is going to finance efforts to reverse course and adapt to the increasingly destructive impacts of climate change continue to dominate.

"Developing countries have to make a choice," said the head of global political strategy, pointing out that they are working with limited resources. "Every day, they have to choose between feeding people on the ground or investing in solar technologies."

Speaking with reporters, he stressed that "finance and equity are going to determine whether we put the world on the right track or it's going to be a doomsday scenario."

"The success of the global stocktake will ultimately determine the success of COP28," wrote UN climate chief Simon Stiell. "It is the defining moment of this year, this COP and — as one of the only two stocktaking moments in this decisive decade of climate action — ultimately pivotal to whether or not we meet our 2030 goals."
How does the global stocktake work?

The idea for the global stocktake came out of the 2015 Paris deal, with countries agreeing to regularly assess how the world was slashing greenhouse gas emissionsadapting to the impacts of a changing world and securing the necessary funds to address the climate crisis.

"The global stocktake is an ambition exercise. It's an accountability exercise. It's an acceleration exercise," said Stiell. "It's an exercise that is intended to make sure every party is holding up their end of the bargain, knows where they need to go next and how rapidly they need to move to fulfill the goals of the Paris Agreement."

The first part of the process, which began back in 2021 and ended earlier this year, involved collecting the latest data on emissions, adaptation efforts and countries' nationally determined contributions, or national climate action plans.

The second phase, the technical assessment which concluded at the Bonn talks in June, gave experts and climate representatives the chance to evaluate the data ahead of political discussions at COP28.

Singh said most international agreements don't have a process like the global stocktake, which allows a periodic review and a chance to develop a forward-looking plan.

"It's unique, a really important process. But we need to make sure it is meaningful, and not just a technical process which will not lead to ambitious action," he said.
Stocktake an 'opportunity to chart a better course'

David Waskow, of the US-based think tank World Resources Institute, said ahead of the Bonn conference that the global stocktake will help shape how countries update their nationally determined contributions in key areas like energy transition, food systems, transport and sustainable consumption, a process they must do by 2025.

"The stocktake was quite explicitly designed to inform the next round of NDCs," he said. "This is really an opportunity to show how the implementation will happen, how the transformation will happen."

"The timing is really important," Singh told DW. "We've heard from scientists, we know what is needed. Now what we need is a political direction. And that's what the world leaders have to deliver."


This article was upated on December 5, 2023 with the latest from the COP28 climate conference in Dubai.

Edited by: Tamsin Walker

COP28: Fossil fuel CO2 emissions to hit record high in 2023

DW 
24 hours ago

As world leaders meet at the UN climate summit in Dubai, a new report shows that carbon emissions are set to hit a record high, with the potential to make climate change worse and fuel more destructive, extreme weather.

As COP28 continues in Dubai, researchers predict record high levels of carbon emissions this year
 Amr Alfliky/REUTERS

Global carbon dioxide (CO2) emissions from the burning of coal, oil and gas are expected to hit a record high in 2023, according to a report released on Tuesday.

The Global Carbon Budget report, published by scientists from more than 90 institutions around the world, said total global CO2 emissions are set to hit 36.8 billion metric tons in 2023 — a 1.1% increase on 2022.


Chiefly responsible for the increase, according to the report, are India and China.

The rise in India is a result of power demand growing faster than its renewable energy capacity, leaving fossil fuels to make up the shortfall. In China, fossil fuel emissions have risen dramatically since the lifting of COVID-19 restrictions.

"The effects of climate change are obvious all around us, but efforts to reduce carbon emissions through the burning of fossil fuels remain painfully slow," said Professor Pierre Friedlingstein from the University of Exeter in the United Kingdom, who led the research.

"It now looks inevitable we will overshoot the 1.5 C target of the Paris Agreement," he added, referring to the attempt to prevent global warming from exceeding 1.5 degrees Celsius above pre-industrial times.


COP28 in Dubai: Calls for fossil fuel phase-out

The publication of the Global Carbon Budget report comes as government representatives and industry leaders gather at COP28, the United Nations climate change conference being hosted this year in Dubai in the United Arab Emirates (UAE).

"Leaders meeting at COP28 will have to agree rapid cuts in fossil fuel emissions even to keep the 2C target alive," said Professor Friedlingstein.

According to a draft negotiating text seen by the Reuters news agency on Tuesday, some participating countries at the climate conference are considering calling for a formal phase-out of fossil fuels as part of the summit's final deal to fight global warming.

But major oil and gas producers, including Saudi Arabia and Russia, have historically resisted such proposals. Saudi Arabia's Energy Minister Prince Abdulaziz bin Salman told Bloomberg TV that his country would "absolutely not" agree to a deal that calls for a phase-down of fossil fuels.

A second option listed in the draft calls for "accelerating efforts toward phasing out unabated fossil fuels," while a third option would be to avoid mentioning a fossil fuel phase-out altogether.

"We're not talking about turning the tap off overnight," German Climate Envoy Jennifer Morgan said. "What you're seeing here is a real battle about what energy system of the future we are going to build together."


How likely is a meaningful deal?

On the COP28 main stage, the chief executives of several major energy firms argued in favor of oil and gas, and sought to highlight their climate-friendly credentials such as cutting emissions of the greenhouse gas methane.

"We are big guys and we can do big things. We can deliver results and we will have to report them very soon," said Jean Paul Prates, CEO of Brazil's state-run oil company Petrobras.

TotalEnergies CEO Patrick Pouyanne said: "We need absolutely to produce oil and gas in a different way by slashing emissions. And we can do it, we have the technology." But he said it would take a long time.

David Waskow, director of World Resources Institute's international climate initiative, said he did not think a COP28 outcome was possible without a clear mandate for moving away from the global reliance on oil, gas and coal.

"I don't think we're going to leave Dubai without some clear language and some clear direction on shifting away from fossil fuels," he said.

mf/nm (Reuters, dpa)

A fossil fuel phaseout or phasedown: Does it matter?
DW
18 hours ago

Early drafts of the COP28 agreement refer to the "phasedown/out" of fossil fuels, which are responsible for most climate emissions. The final wording will likely be disputed. What's the difference — and does it matter?


People in the Indian capital of New Delhi regularly suffer from weeks of poisonous smog
 Jewel Samad/AFP

The heated issue of fossil fuel energy, which is responsible for most of the planet-warming greenhouse gas emissions in the atmosphere, has always been divisive at UN climate conferences.

The fact that this year's summit is being hosted by petrostate United Arab Emirates (UAE), a global leader in the oil and gas industry, is focusing the spotlight on the issue even more.

Sultan al-Jaber, who is presiding over this year's COP28 climate talks and also runs the host nation's state-run oil giant ADNOC, has denied media reports in which he appeared to question the scientific consensus that coal, oil and gas must be phased out to curb global warming.

Speaking with reporters on December 4, al-Jaber insisted his remarks had been taken out of context and that he is "laser-focused" on finding a way to limit global temperatures to 1.5 degrees Celsius (2.7 degrees Fahrenheit) above pre-industrial times.

"I have said over and over that the phasedown and the phaseout of fossil fuels is inevitable, that it is essential," said al-Jaber.

Phaseout, phasedown: What's the difference?


It might only be a word of difference, but it is meaningful.

The phasing down of fossil fuels would mean that countries agree to scale back their use of fossil fuels in favor of more climate-friendly energy — non-fossil sources like wind, solar and hydro, and nuclear energy. But it still implies that fossil fuels would be a part of the world's energy mix as efforts to get climate change under control continue.

A phaseout, however, calls for a complete end to burning fossil fuels for energy. That action plan, so far, hasn't found much support with delegates at previous climate summits, especially from nations relying on oil and gas exports for revenue.



Major producers like the United States, Russia and Saudi Arabia have previously resisted calls for eliminating the use of fossil fuels. Most recently, on December 4, Saudi Energy Minister Abdulaziz bin Salman said he would "absolutely not" agree to phasing down fossil fuels, never mind phasing them out.

"And I assure you not a single person — I'm talking about governments — believes in that," he told Bloomberg TV.

Earlier this year, UAE Climate Change and Environment Minister Mariam Almheiri instead backed the phasing out of fuel emissions, not the exploitation of oil, gas and coal. She argued that a phaseout would only hurt countries that depend on fossil fuels to prop up their economies.

"The renewable space is advancing and accelerating extremely fast but we are nowhere near to be able to say that we can switch off fossil fuels and solely depend on clean and renewable energy," Almheiri told the Reuters news agency.

"We are now in a transition and this transition needs to be just and pragmatic because not all countries have the resources," she said. A November 2023 report by the UN Environment Programme (UNEP) found that the UAE's state oil company, ADNOC, has a $150-billion (€140-million) investment plan to boost its oil production capacity by 2027.



Instead, Almheiri suggested eliminating fossil fuel emissions using carbon capture and sequestration technology, saying countries could fight warming and continue to produce oil, gas and coal.

Critics, however, have said this approach would be too expensive. And with less than 0.1% of global emissions captured by such technology today, according to research firm BloombergNEF, it's unlikely to be a significant part of the solution any time soon.
Calls for phaseout relatively new at COP

Even though vast body of scientific research has linked back the ongoing use of fossil fuels to climate change for years, COP delegates have not officially spoken about plans to eliminate them until recently.

It was only two years ago at COP26 in Glasgow that negotiators agreed, for the first time, to "phase down unabated coal power and inefficient subsidies for fossil fuels."

A year later at UN climate talks in Egypt, a group of more than 80 countries including the European Union and small island nations agreed to upgrade that language to include all fossil fuels. They were ultimately blocked by oil, gas and coal-producing nations opposed to the move.

Despite the 2022 setback, campaigners hope the UN's first global stocktake report, released in September as a review of the world's collective progress toward limiting global heating, will spur delegates to action in Dubai. The UN report called for "scaling up renewable energy and phasing out all unabated fossil fuels," a recommendation echoed by many climate groups and scientists.

"Even a few years ago, it was unthinkable to have a decision on fossil fuel phaseout at COP because of the influence of oil and gas producing countries," Romain Ioualalen of the advocacy organization Oil Change International told DW.

With global carbon dioxide emissions expected to hit a record high in 2023, UN Secretary-General Antonio Guterres said at the opening of the COP28 climate summit on December 1 that it was time to act.

"We cannot save a burning planet with a firehose of fossil fuels," he said. "The science is clear: the 1.5-degree limit is only possible if we ultimately stop burning all fossil fuels. Not reduce. Not abate. Phaseout — with a clear timeframe aligned with 1.5 degrees."

Edited by: Tamsin Walker

Frontiers is gearing up for COP28 to address the climate emergency


Meeting Announcement

FRONTIERS




The United Nations Framework Convention on Climate Change (UNFCCC) parties meet every year at the Conference of the Parties (COP) to negotiate and agree action on how to tackle climate change, limit emissions, and halt global warming. These gatherings are the world's highest decision-making body on climate issues and one of the largest international meetings in the world. COP28 will provide a milestone opportunity for the world to come together, course correct, and drive progress to keep 1.5C within reach - so we can meet the goals and ambitions of the Paris Agreement. It will be a pivotal moment for the world to unite around tangible climate action and deliver realistic solutions.  

Addressing climate change, the paramount challenge of our era, hinges upon harmonizing fundamental human needs with sustainable climate remedies. Despite heightened awareness and global pledges, advancements in climate action have lagged and, at moments, fallen short. Confronting this hurdle, open science emerges as a pivotal force for innovation and a driver of groundbreaking solutions, playing a vital role in addressing climate change challenges. 

As world leaders convene at COP28 in an effort to reach consensus on actions to prevent the planet from surpassing the 1.5-degree limit, making scientific data and publications openly accessible is a crucial component of any proposed strategy and measures.  With numerous nations having embraced open science principles, a global agreement to strengthen them is within reach at COP28 and would constitute a tangible achievement.  

FRONTIERS ON A MISSION  

Open science platform Frontiers and the Frontiers Research Foundation will participate in the 28th session of the COP, taking place from 30 November to 12 December in Dubai, United Arab Emirates, to ascertain the undeniable power of open science and advance the mission to make science open so that scientists can collaborate better and innovate faster to deliver the solutions that enable healthy lives on a healthy planet.  

As an open access publisher, Frontiers is committed to fostering open and transparent scientific communication and collaboration if we are to stand a chance to find solutions to the biggest challenge of our time. During COP28, Frontiers will showcase its latest initiatives to support global efforts to combat climate change, achieve the United Nations Sustainable Development Goals (SDGs), and fulfill the goal of becoming net-zero by 2050.   

FRONTIERS IN ACTION AT COP28  

The urgent nature of the climate crisis demands swift and comprehensive action. Our world stands at the cliff face of irreversible changes, each carrying severe consequences for life as we know it. To combat this, a diverse range of scientific solutions is imperative, and the most effective catalyst lies in making science open. It is the simplest and most cost-effective accelerator for scientific solutions and to save lives. To discuss the pathways towards innovative, sustainable solutions and actions, Frontiers will host several panels in Dubai featuring prominent experts and decision makers from policy, academia, and industry.  

UN Climate Change Global Innovation Hub Opening Ceremony 

This session will officially open the UN Climate Change Global Innovation Hub (UGIH) COP28 dialogue and feature high-level statements from UGIH supporting partners on their reasons for engagement and plans moving forward. Frontiers’ collaboration with the UGIH will be embodied in commitment to co-develop the Hub’s Digital Platform as a Knowledge partner and to assist in disseminating the UGIH workshops’ outcomes through Frontiers’ journals and Policy Labs, which will be consolidated in official signing of the Memorandum of Understanding between Frontiers and the UNFCCC. Moderated by Jorn Verbeeck, KPMG Sustainability and ESG Senior Manager and Board Member of EU Climate Neutral and Smart Cities Mission, the panel will include: 

  • Nitin Arora, Project Manager, UN Climate Change Global Innovation Hub 

  • Massamba Thioye, UN Framework Convention on Climate Change 

  • Kirsten Dunlop, CEO, Climate-KIC 

  • Dennis Pamlin, Executive Director, Mission Innovation 

  • Martin Wainstein, Executive Director, Open Earth Foundation 

  • Andy Deacon, Co-managing Director, Global Covenant of Mayor 

  • Luis Neves, CEO, Global Enabling Sustainability Initiative 

  • Frederick Fenter, Chief Executive Editor, Frontiers 

  • Stephan de Haas, Head of Co-Creation and Client Consulting, T-Systems International. 

Watch the session here

Systems Change and Innovation for Climate and Sustainability Action  

How can innovation serve climate and sustainability goals for the benefit of people and the planet? This is the question that will guide this high-level session, which will explore how a need-based and solution-oriented approach to innovation, combined with moonshot mindsets and systems thinking, can enable climate and sustainability solution providers to act appropriately. Additionally, the session will discuss identifying, developing, and scaling these transformative and ambitious solutions in alignment with climate goals. Moderated by Massamba Thioye, the panel will be represented by: 

  • Catarina Selada, Head of Policy and Intelligence Unit, Centre of Engineering and Development 

  • Jean-Claude Burgelman, Director, Frontiers Planet Prize, former Head of Open Science Unit, European Commission 

  • Anna Stanley-Radière, Director, Climate Transparency, Co-leader, World Business Council for Sustainable Development 

  • Mike Hayes, Climate Change and Decarbonization Leader, Global Head of Renewable Energy, KPMG International. 

Watch the session here.  

Open Science for Inclusive and Transformative Climate and Sustainability Innovation 

Climate change requires global cooperation, yet reconfiguring infrastructure systems for a zero-carbon world proves cost-prohibitive for many nations. Recent events like the COVID-19 pandemic have demonstrated the power of open knowledge sharing to supercharge innovation and deliver timely solutions. Open science can offer equally transformative change when applied to the existential threats posed by climate change that respond to core human needs. Moderated by Henry Markram, co-founder of Frontiers and professor of neuroscience at the Swiss Federal Institute of Technology Lausanne (EPFL), this panel will explore the advantages of open science as an accelerator of inclusive and sustainable climate innovation. Private and public sector leaders will discuss the importance of making scientific results openly available in order to boost innovation, increase public consensus, and bolster political will to act. Panelists will include: 

  • Vladimir Ryabinin, UNESCO Assistant Director-General; Executive Secretary, Intergovernmental Oceanographic Commission (IOC)   

  • Maria Espinosa, former UN General Assembly President UNGA; former Ecuador External Affairs Minister 

  • Diarmid Campbell-Lendrum, Climate Change and Health Unit Head, World Health Organization  

  • Gavin McCormick, Executive Director, WattTime; Co-founder, Climate TRACE 

  • Lars Peter Riishøjgaard, Director, World Meteorological Organization. 

Watch the session here

The timing of this panel corresponds to the official launch of the Open Science Charter, an initiative by the Frontiers Research Foundation, which urges governments, research institutions, and funders, as well as industry leaders and citizens of the world to commit and act in four main areas: 

  1. Unrestricted access to scientific knowledge by 2030: Commit to transitioning all published research articles from subscription to fully open-access models before the end of this decade.   

  1. Uphold peer-review quality: Preserve and champion the core values of scientific publishing, including registration, validation, certification, and perpetual conservation of scientific findings.   

  1. Transparent pricing linked to quality: Adopt transparent financial models that directly correlate the price of publication with the quality of services offered.   

  1. Strengthen trust in science: Make the knowledge available to the public who helped pay for it and who will benefit from its accessibility. 

Read and sign The Charter here.     

Pathways to a Sustainable Earth: Unlocking Solutions through Transformational Science 

How can transformational science be used to unlock breakthrough, scalable solutions for our planet? This session will critically examine the key obstacles and challenges that must be addressed today to fully harness the potential of transformational science as the basis for policy discourse. It will also draw upon the expertise of diverse stakeholders and seek to find consensus on what the missing links are that translate science into action, and what most effective dissemination mechanisms and outlets are needed to bridge this gap. Moderate by Wendy Broadgate, from Future Earth and the Earth Commission, this panel will welcome the following panelists: 

  • Sandrine Dixson-Decleve, Co-President, Club of Rome 

  • Joeri Roelji, Director of Research, Grantham Institute; Professor of Climate Science and Policy, Imperial College London 

  • Paul Behrens, Leiden University, Frontiers Planet Prize international champion 2023 (virtual) 

  • Clea Kaske-Kuck, Director, Partnerships and Stakeholder Engagement, World Business Council for Sustainable Development 

  • Lars Peter Riishøjgaard, Director, Global Greenhouse Gas Watch, World Meteorological Organization (WMO) 

  • Frederick Fenter, Chief Executive Editor, Frontiers 

Watch the session here

Embracing Open Science for the Climate Crisis: Collaborative Solutions for a Resilient Future 

The session will explore how various disciplines and stakeholders are navigating new frontiers of open science in the context of the climate crisis. It will offer international perspectives on current and future applications of open science in biodiversity, physical science, and ESG (environmental, social, and corporate governance), while seeking to find corporate-academia synergies using open science for community resilience. Moderated by Sheeba Nettukandy Chenoli of University Malaya, the panel will consist of:  

  • Shaliza Binti Ibrahim, Deputy Vice-Chancellor, University Malaya; Co-Chair, Malaysia Open Science Alliance 

  • Anna Pirani, Head, WGI Technical Support Unit (TSU), Intergovernmental Panel on Climate Change (IPCC)  

  • Tan Sri Zakri Abdul Hamid, Technology and Innovation Cluster Lead, MNRECC Advisory Panel for COP28  

  • Martin Siegert, Co-director, Grantham Institute - Climate Change and Environment 

  • Dato' Ami Moris, Board Member, University Malaya; Advisor, Maybank. 

ADVANCING CLIMATE ACTION RESEARCH 

COP28 in Dubai will witness the presentation of the new research article The Zero Emissions Commitment and climate stabilization, which was recently published in Frontiers in Science, Frontiers’ flagship multidisciplinary, open-access journal focused on transformational science. The article examines the concept of zero emissions commitment (ZEC), which quantifies the amount of global warming that would occur after greenhouse gas emissions are reduced to zero. In the piece, the authors review the current scientific understanding of ZEC, its uncertainties, and its implications for climate stabilization and policy. Such knowledge is an important addition in navigating transformative pathways towards a climate-stable future. 

As this year's COP28 marks another crucial milestone in the global response to the climate crisis, Frontiers has launched a new research topic to curate a collection of papers presenting COP28's pressing discussions and themes as well as its outcome and solutions. The Advancing Climate Action: Insights from COP28 research topic is a collaborative effort across several Frontiers journals: Frontiers in Environmental Science, Frontiers in Sustainable Resource Management, Frontiers in Climate, Frontiers in Sustainable Cities, Frontiers in Sustainability, Frontiers in Ocean Sustainability, and Frontiers in Sustainable Energy Policy. It invites contributions from various disciplines and sectors on topics such as mitigation, adaptation, and resilience, in addition to cross-cutting issues such as equity, culture, and transformation. To learn more and submit your research, please visit this dedicated research topic page

The climate emergency demands immediate action, and science plays a pivotal role in finding sustainable solutions. Open science, with its commitment to knowledge-sharing, can accelerate our response to the climate crisis and offer solutions. As we start COP28, the time for rhetoric is over. It is the time for action.   



 

No evidence found that cannabis reduces long term opioid use


Caution needed when viewing cannabis as solution to opioid crisis


Peer-Reviewed Publication

UNIVERSITY OF SYDNEY





A 20-year Australian study has found no evidence to suggest cannabis reduces illicit opioid use, and it may not be an effective long-term method of reducing harm for those with an opioid use disorder or problematic use of opioids.

Published in the American Journal of Psychiatry, the University of Sydney led study is one of the longest of its kind.

Between 2001 to 2022, the study involved a group of 615 people with heroin dependence, many of whom also used cannabis.

Additional analysis also found no consistent evidence between cannabis and other opioid use, including opioids that were prescribed.  

Opioid use is currently responsible for more death and disability than any other illicit drug. Opioid and cannabis use disorders make up approximately 77 percent of all illicit drug disorders.

The researchers say clinicians and policymakers should be cautious about relying on cannabis to reduce problematic opioid use or as a potential strategy to help manage the opioid crisis, especially given a global shift towards cannabis legalisation and recognition as a therapeutic product.

In the United States, some states have policies that allow patients to substitute their prescribed opioids with cannabis.

The Canadian Government is currently reviewing the Cannabis Act in the context of medicinal cannabis for opioid dependence.

To examine the impact of cannabis on opioid use, and vice versa, researchers used a recently developed statistical technique. This allowed them to account for influential factors on opioid and cannabis use in the data such as age and made it possible to focus on individual changes in substance use over time.

“Our investigation shows that cannabis use remains common among this population, but it may not be an effective long term strategy for reducing opioid use ,” says lead author Dr Jack Wilson, from The Matilda Centre for Research in Mental Health and Substance Use, at the University of Sydney.

“There are claims that cannabis may help decrease opioid use or help people with opioid use disorders keep up with treatment.

“But it’s crucial to note those studies examine short- term impact, and focus on treatment of chronic pain and pain management, rather than levels of opioid use in other contexts.”

Another key finding was cannabis use is common among those with an opioid use disorder, and so there needs to be clinical services that offer additional support for people who would like to reduce cannabis use.

“Opioid use disorders are complex and unlikely to be resolved by a single treatment,” says Dr Wilson.

“The best way to support them is evidence-based holistic approaches that look at the bigger picture, and include physical, psychological, and pharmacotherapy therapies.”

-ENDS-

 

What smoking does to oral bacteria


A study shows the effects of cigarette use and what happens when you stop


Peer-Reviewed Publication

EURAC RESEARCH





The father of Biotechnologist Giacomo Antonello, a dentist, sometimes amazed patients with his seemingly clairvoyant diagnostic abilities: one look in their mouth and he would advise them to see a specialist, because, he explained, they might have a problem with their heart or diabetes.  He often turned out to be correct. While his patients were always very impressed, for experts, the dentist’s diagnoses were justified: empirical studies show that there is often a connection between periodontitis and various cardiovascular diseases, even if the exact mechanisms are not fully understood.  Giacomo, who is currently conducting research for his PhD at the Institute of Biomedicine, has now just completed a study with colleagues at the Eurac Research Institute for Biomedicine that points to one possible factor: in people who smoke, the alteration of the healthy community of oral bacteria could contribute to the increased risk of these diseases. 

 

The study, which was conducted as part of the CHRIS study in Val Venosta, asks two central questions: What exactly happens to the bacterial community in the mouth, the so-called oral microbiome, when we smoke? And what effect does quitting have on these same communities? 

To find out, the research team in Bolzano, together with epidemiologist Betsy Foxman from the University of Michigan, analyzed saliva samples from more than 1600 people – a huge number of subjects for this research field, as bioinformatician Christian Fuchsberger, Giacomo’s doctoral advisor, emphasizes: “There are hardly any large studies on the salivary microbiome. This is a young research field in which a lot is happening right now and one in which not everything is conducted so clearly. Many of the current studies are working with very small numbers of cases, for example, which means their results are not broadly applicable.” 

 

Microbiome research is a fairly young field: just a few decades ago, the communities of trillions of microorganisms that live on and in humans – mostly in the digestive tract – were considered of little significance by scientists. Now, the microbiome is taking center stage and is recognized to be of massive importance to our development and health. The intestinal microbiome is the subject of intensive research with a major study currently underway at the Institute of Biomedicine (see box).  

Compared to the microbial density of the intestine, where thousands of strains of different bacteria live, our mouth is only sparsely populated. However, saliva has a particular advantage for studies: it is relatively easy to sample. Researchers can therefore acquire the data they need to investigate whether it is possible to identify changes in the oral flora (biomarkers) that indicate certain diseases, which, if found, could provide a valuable diagnostic tool that healthcare systems could easily employ. 

 

In the CHRIS Study’s examination, CHRIS participants were requested to spit 5 milliliters of saliva into a special collection tube. The participants were divided into groups according to whether they were current smokers, had stopped smoking, or had never started. Those who had quit were asked exactly when they had quit, and those who still smoked were asked about the number of cigarettes they smoked per day. To get a picture of the microbial community in each mouth – which species were represented and at what frequency – the research team employed a universally used technology for identifying bacteria, namely sequence analysis of the 16S rRNA gene, a gene which represents something like an “identity card” for each different species. 

 

Giacomo’s research using the microbiome data collected in the CHRIS Study showed clear results. People who have never smoked carry a significantly different microbial community in their mouths than people who still smoke or have recently given up. Cigarette consumption primarily affects the bacteria that need oxygen:aerobic bacteria. The number of these bacteria decreases continuously the more cigarettes one smokes; if one stops smoking, these aerobic bacteria gradually increase again. And the longer the smoke-free period, the more aerobic bacteria are found in the saliva. Only after five years of not smoking are former smokers indistinguishable, in terms of aerobic bacteria in their oral microbiome, from people who have never smoked. “We have observed that the effects of smoking persist for years,” Fuchsberger says. “So then, of course, it’s interesting to ask whether these effects are related to certain diseases.” 

 

Smokers are known to have an increased risk of both periodontitis and cardiovascular disease. Could the changes in the oral microbiome caused by cigarettes use play a role in this? This is where a function of the bacteria that live in the mouth comes into play, and like everything to do with our microbiome, it has been receiving increasing attention for some time – some of these bacteria, mainly aerobic ones, convert the nitrate we ingest with food into nitrite, which then become nitric oxide. Nitric oxide is an important substance for regulating blood pressure, among other things. If too little nitric oxide is available, this could contribute to poorly perfused gums and cardiovascular disease. Now, the study in the Venosta valley did not measure nitric oxide in saliva, but it did examine the microbes in it; all the research team can say, therefore, is that the more the subjects smoked, the fewer nitrate-reducing bacteria lived in their mouths. That this could be an additional explanation for why smokers have a higher risk of periodontal disease and cardiovascular disease is “a hypothesis that needs to be tested in further studies,” Giacomo emphasizes.  

He is already pursuing the next question based on the CHRIS samples. Namely, what are some of the other factors that influence our oral flora and to what extent? What role does genetics play, and what role do the people we share households with also play?  He will only be able to answer this question in about a year’s time, but one thing is already very clear: who we live with is very important. 

 

Digital emblem for humanitarian law in cyberspace


Peer-Reviewed Publication

ETH ZURICH




Ransomware attacks can paralyse organisations or entire countries by hacking into a network and encrypting critical data. The attackers then demand a ransom; if their demands aren’t met, the data will not be decrypted and may be lost forever. Depending on the given situation, the financial and logistical damage can be enormous. In January 2022, the International Committee of the Red Cross (ICRC) was the victim of a cyberattack. Data belonging to more than 500,000 people around the world was stored on the affected servers. This included data on people who needed special protection, such as missing persons, refugees from war zones and prisoners. “The ICRC’s digital infrastructure has grown considerably in recent years – and so has the number of cyberattacks on our systems,” says Mauro Vignati, Adviser Digital Technologies of Warfare at the ICRC. Particularly during wars and armed conflicts, such cyberattacks could also have catastrophic humanitarian consequences, for example if the digital infrastructure of a hospital is paralysed by the enemy.

Trusted emblem for protection against attacks

For conflicts beyond cyberspace, the ICRC has employed protective emblems since the Geneva Conventions of 1949, the core of international humanitarian law. The red cross, red crescent and red crystal provide protection for hospitals, vehicles and employees of organisations in the International Red Cross and Red Crescent Movement network (including the ICRC). Today, the network has over 80 million members who are active in 192 countries. As a matter of principle, bearers of these emblems are protected by international humanitarian law, especially in conflicts. Warring parties are not allowed to attack them. “That’s why we’ve been wondering for some time whether we could also develop an emblem to protect our digital infrastructure,” Vignati says. Such a system would have to fulfil a number of requirements: “It should be easy and cost-​effective to integrate into existing digital systems worldwide and easy to maintain. It would also have to bridge linguistic, technological and cultural differences.” What’s more, the emblem ought to be as flexible as possible. In certain situations, it’s important for ICRC staff to mask the emblem, Vignati says.

Three years ago, the ICRC contacted the Centre for Cyber Trust, a research collaboration between ETH Zurich and the University of Bonn in the field of cybersecurity, with this idea of establishing a digital emblem. One of the people working on this since then is Felix Linker, who is currently writing his doctoral thesis in the group led by David Basin, Professor of Information Security at the Department of Computer Science at ETH Zurich. “A digital emblem has a unique combination of security requirements, namely authenticity, accountability and a property that we call covert inspection,” Linker says. The Authentic Digital EMblem (ADEM), which he has developed together with Basin, is based on the web PKI and CT ecosystem (Web PKI and CT stand for Web Public Key Infrastructure and Certificate Transparency). “We rely on existing best practices on the internet. What makes our work innovative is how we’ve combined different solutions to meet the technical requirements,” Linker says. In an article recently published in the Proceedings of the 2023 ACM SIGSAC Conference on Computer and Communications Security, Linker and Basin describe in detail for the first time how ADEM works.

Machine-​readable and decentralised

The emblem they have developed is cryptographically secured using a digital signature – a long sequence of bits that can be read by a program developed for this purpose. This makes it possible to retrieve information about the owner, the IP or domain worthy of protection, as well as the publisher of the emblem. “It’s important that the emblem can be read by machines, because most cyberattacks today are automated,” Linker says. In other words, hacker software needs to automatically load and read the emblem, so it can recognise that it is accessing a system belonging to an organisation that is protected by international humanitarian law. And that needs to happen during the software’s first reconnaissance, before it does any damage to the system.

Another key requirement is for the digital emblem to be managed in a decentralised way rather than by a central authority. States that are committed to international humanitarian law should be able to verify that a certain digital infrastructure on their territory is entitled to protection and therefore bears an emblem. To this end, ADEM is based on an open standard, so governments can adapt the emblem’s implementation as flexibly as possible to their own requirements.

Hackers remain undetected

Potential attacks on servers and networks can come from hacker groups, but also from states during a war. These want to remain undetected at all costs. “That’s why attackers must be able to view the emblem without either the protected institution or the issuer of the digital signature being able to tell that the emblem has been looked at.” Only then will potential attackers be prepared to have their systems run the scanner for detecting the emblem. “Standard internet authentication protocols aren’t suitable for this because they require interaction between the two parties involved,” Linker says. “That attracts attention, which means it won’t work in a conflict.” He managed to come up with a combination of suitable internet protocols (UDP, TLS and DNS) to mask the distribution of the emblem.

Linker has now evaluated the system in a security analysis under a comprehensive threat model. His evaluation shows that the digital emblem cannot be misused by attackers and acts as a security guarantee. He says that this provides proof of concept. He is now developing the first prototypes further, while colleagues from the Centre for Cyber Trust in Bonn will conduct interviews with hackers to find out how willing people are to respect such an emblem. After all, only then will they bother to run a program that can recognise emblems. But this is something Linker is confident about: in the past, hackers have been known to avoid humanitarian targets on occasion, “for ethical reasons or simply to avoid attracting too much attention.”

Difficult legal implementation

Vignati from the ICRC is satisfied: “ADEM fulfils all our original requirements for a digital emblem.” The main task now is to further optimise the emblem’s visibility to potential attackers. However, it will probably be several years before the digital emblem actually starts helping to protect the ICRC’s critical digital infrastructure and hospitals in war zones. “The legal implementation is very challenging,” Vignati says. Implementing the emblem in the legal framework calls for adjustments to the Geneva Conventions: “Either through a new additional protocol or through an addition to the existing protocols.” The ICRC plans to showcase ADEM, along with another system designed at John Hopkins University, at an international humanitarian law conference to be held in October 2024. It will also present legal pathways for bringing the digital emblem into operation. “That would be an important first step in strengthening humanitarian protection in cyberspace,” Vignati says.