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Friday, October 16, 2026

 

Online sports betting legalization linked to increased use of depression and anxiety treatment



Study analyzed insurance claims in US states before and after legalizing online sports betting




Johns Hopkins Bloomberg School of Public Health






States in the U.S. that legalized online sports betting saw increases in the use of depression and anxiety medications as well as outpatient diagnoses for depression and anxiety, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

The researchers used a large national dataset of employer-sponsored health insurance claims from January 2016 to December 2023, a period in which online sports betting became legal in many states, for their analysis. The team compared insurance claims of individuals in the 22 states that legalized online sports betting between 2018 and 2022 and those in 13 “control” states that had not legalized online sports betting by the end of 2023. The researchers excluded states that legalized online sports betting in 2023 or prior to 2018.

The study found that states saw significant increases in filled prescriptions for antidepressants and anti-anxiety medications, as well as outpatient diagnoses of depression and anxiety, after legalizing online sports betting.

The study was published online October 14 in JAMA Psychiatry.

“I hope these results will increase awareness among psychiatrists and primary care doctors who treat mental health, as well as online sports bettors themselves, that these online apps can lead to harms beyond financial risks,” says study senior author Mark Meiselbach, PhD, an assistant professor in the Bloomberg School’s Department of Health Policy and Management.

The study’s first author was Ben Westermeyer, a PhD candidate in Meiselbach’s research group.

The past several decades have seen a loosening of gambling restrictions. Online sports betting, following a 2018 U.S. Supreme Court ruling, is now legal in most U.S. states, and is dominated by “sportsbook” apps such as DraftKings and FanDuel. Today, tens of millions of Americans participate in online sports betting, though estimates vary.

Gambling is increasingly framed as a public health issue. Researchers have linked gambling to anxiety, depression, substance use, and other mental health problems—including “gambling disorder,” an addiction disorder.

To better understand potential impacts of online sports betting, the researchers looked for changes at the state level, before and after legalization, in the percentage of insurance enrollees with one or more prescription fills for antidepressant, anti-anxiety, or substance use disorder medications; or one or more outpatient, emergency department, or inpatient visits with a diagnosis of depression, anxiety, or substance use disorder.

The analysis found that legalization was associated with increased probabilities of an outpatient diagnosis of depression—a 6.73% increase for men and 5.47% increase for women, relative to the sample averages—and with increased probabilities of using antidepressant medications (+5.44% for men, +5.00% for women).

The findings were similar for anxiety: +7.20% and +6.50% increases in the probability of an anxiety disorder outpatient diagnosis, and +4.99% and +5.17% increases in the probability of using anti-anxiety drugs, for men and women respectively.

The analysis found no significant increase in the probabilities of substance use disorder diagnoses or medication use. The researchers also found no evidence for increased probabilities of emergency department or inpatient visits resulting in depression or anxiety diagnoses.

“Overall, these findings support the concern that there are broad mental health effects of online gambling legalization, though those who are experiencing those effects, and their clinicians, don’t necessarily attribute it to gambling,” Westermeyer says.

The authors note that the study was limited to people with employer-sponsored health insurance and does not measure the effects of legalization on other groups. Additionally, the researchers could not link individual-level sports betting to changes in healthcare use because insurance claims data do not capture whether people bet on sports.

The researchers now hope to conduct more targeted studies of the issue, using datasets that allow them to more directly measure online sports betting alongside mental health measures.

“I think there’s room for us to zero in on this a bit more,” Westermeyer says.

“Online Sports Betting Legalization and Behavioral Health Care Use” was co-authored by Benjamin Westermeyer, Matthew Eisenberg, and Mark Meiselbach.

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Neighborhood conditions linked to childhood cancer survivors’ long-term health



Survivors living in communities with high social, physical and healthcare-access vulnerability are more likely to develop chronic health conditions, indicating a need for community-level support




St. Jude Children's Research Hospital

Neighborhood conditions linked to childhood cancer survivors’ long-term health

image: 

(L to R) First author Jaesung Choi, PhD, and I-Chan Huang, PhD, both of the St. Jude Department of Epidemiology & Cancer Control

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Credit: Courtesy of St. Jude Children's Research Hospital






(MEMPHIS, Tenn. – October 14, 2026) Survivors of childhood cancer can make lifestyle changes to reduce later-in-life chronic health conditions, such as diabetes and heart disease. Still, some survivors report local environmental barriers to taking these actions. According to a new study from St. Jude Children’s Research Hospital scientists, survivors from the most vulnerable neighborhoods — those with features including low income per capita, poor walkability, a lack of access to nearby healthcare or fewer healthy food options — have a significantly elevated risk. The findings, published recently in eClinicalMedicine, identify a need to consider these community-level factors to better support survivors.

 

Scientists already knew that individual socioeconomic factors were linked to survivors’ long-term health, but the role of the surrounding social and physical environment was less clear. To investigate, the researchers compared neighborhood indicators of vulnerability, such as socioeconomic status, minority status and access to healthcare and food, with repeated clinical assessments of survivors enrolled in the St. Jude Lifetime Cohort Study (St. Jude LIFE) since 2007 to track changes in chronic health conditions over time.

 

“We’ve found that neighborhood conditions likely play a significant role in how survivors’ health outcomes evolve,” said corresponding author I-Chan Huang, PhD, St. Jude Department of Epidemiology & Cancer Control. “That means that we have the beginning of what we need to find effective, accessible and affordable support and interventions to overcome these barriers and improve survivors’ health trajectory.”

 

The researchers revealed that living in the most socially or environmentally vulnerable neighborhoods is associated with a doubled risk of overall chronic health condition burden compared to the least vulnerable neighborhoods. However, they also identified new opportunities to support survivors.

 

“Over the past decades, the substantial efforts made to improve outcomes for children with cancer have focused on limiting therapies with strong links to chronic health problems,” said co-author Melissa Hudson, MD, Department of Oncology. “These findings remind us that it is essential to consider other factors, such as access to food, safe walking venues and primary medical care, in our management of survivors living in disadvantaged neighborhoods.”

 

Finding an intervention target

 

Neighborhood-level interventions will likely require substantial time, money and effort. The study provides first-of-its-kind information to help researchers decide which community barriers to investigate further. When the researchers dug into disease-specific associations, instead of total disease burden, they found larger effects that may help prioritize future testing. For example, poor walkability was associated with a fivefold increased risk of metabolic disease and a tenfold increased risk of a heart attack.

 

These neighborhood factors also intersected with individual risk factors, such as survivors on public insurance who also live in one of the most vulnerable neighborhoods, who had a sevenfold increased risk of muscle and cardiac issues. The complex nature of this means that finding the best way to support patients to decrease their risk of chronic health conditions will require further study.

 

“While treatment history is the most significant determinant of survivors’ chronic disease risk, we found that access to everyday resources in their neighborhoods also matters,” Huang said. “That is promising, as we can’t change what cancer therapy survivors received decades ago, but we can start changing and testing community-level supports for them today.”

 

Authors and funding

The study’s first author is Jaesung Choi, St. Jude. The study’s other authors are Sedigheh Mirzaei, Deo Kumar Srivastava, Nickhill Bhakta, Stephanie Dixon, Matthew Ehrhardt, Carmen Wilson, Angela Delaney, Daniel Mulrooney, Heather Brandt, Kirsten Ness, Gregory Armstrong and Melissa Hudson, St. Jude; Madeline Horan, Wake Forest University School of Medicine; and Yikyung Park, Washington University in St. Louis.

 

The study was supported by grants from the National Cancer Institute (U01CA195547, U01CA301480 and P30CA021765) and the American Lebanese Syrian Associated Charities (ALSAC), the fundraising and awareness organization of St. Jude.

 

St. Jude Media Relations Contact

Michael Sheffield
Desk: (901) 595-0221
Cell: (901) 379-6072
michael.sheffield@stjude.org
media@stjude.org

 

St. Jude Children's Research Hospital

St. Jude Children’s Research Hospital is leading the way the world understands, treats, and cures childhood catastrophic diseases. As the only National Cancer Institute-designated Comprehensive Cancer Center devoted solely to children, St. Jude advances groundbreaking research and shares its discoveries worldwide to accelerate progress in pediatric medicine. Treatments developed at St. Jude have helped push the overall childhood cancer survival rate from 20% to more than 80% since the hospital opened more than 60 years ago. Through collaboration and innovation, St. Jude is working to ensure that children everywhere have access to the best possible care. To learn more, visit stjude.org, read St. Jude Progress, a digital magazine, and follow St. Jude on social media at @stjuderesearch.

Thursday, October 15, 2026

 

Many states with higher burden of alcohol use disorder among women have fewer treatment facilities tailored to their needs



A new study found that states in New England, the Midwest, and West had a higher prevalence of alcohol use disorder among women, but fewer services that address women’s unique concerns and common barriers to alcohol treatment.



Boston University School of Public Health






A new study found that states in New England, the Midwest, and West had a higher prevalence of alcohol use disorder among women, but fewer services that address women’s unique concerns and common barriers to alcohol treatment.

The historical gap in binge drinking, alcohol use disorder (AUD), and alcohol-related deaths between men and women has narrowed substantially over the last several decades in the United States, with binge drinking rates among women ages 18-25 exceeding men’s rates in the same age group for the first time in 2024. 

With this rapid increase in risk for AUD and AUD-related complications, women could benefit substantially from alcohol treatment programs that are tailored to their unique needs. But there is a dearth of knowledge on the availability of women-specific alcohol treatment in the US and how these services may differ by state. 

A new study led by researchers at Boston University School of Public Health (BUSPH) now fills this gap, finding that the estimated prevalence of AUD among women—as well as the availability of women-specific alcohol treatment services—vary widely across US states. 

Published in Substance Use & Addiction Journal, the results showed that estimated state-level AUD among women ranged from approximately 6-13 percent, with all New England states and several in the West and Midwest exceeding the national average of 8 percent among women. More than 40 percent of addiction treatment facilities did not offer women-specific treatment, and services targeted toward women—especially childcare—were disproportionately unavailable in many states that had higher-than-average estimated AUD prevalence among women. The study was funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and is the first to explore state-level differences in AUD among women and the availability of women-specific services in treatment facilities.

“Women are drinking more and experiencing significant health consequences from alcohol use,” says study senior author Dr. Maureen Stewart, research associate professor of health law, policy & management at BUSPH. “At the same time, alcohol treatment rates are abysmally low. Our findings show there is a substantial need for treatment targeted toward women’s unique experiences. Making alcohol treatment more tailored to women’s needs could help women access treatment."

Research shows that alcohol treatment programs that are tailored to women’s needs have had greater success in reducing substance use and mental health symptoms among women than programs that lack these services, she adds. "Knowing the states in which women bear the greatest burden of AUD yet lack access to treatment services for their needs can help direct resources efficiently and reduce the barriers preventing women from accessing treatment."

For the study, researchers from BUSPH, Columbia University Mailman School of Public Health (Columbia), and Boston Medical Center’s (BMC) Grayken Center for Addiction utilized publicly available national and state-level data to estimate the state-level prevalence of AUD among women, as well as the state-level prevalence of addiction treatment facilities offering women-specific services in 2024 and the proportion of facilities with these specialized services per 10,000 adult women with AUD. 

The estimated prevalence of AUD among women ranged from 6.2 percent of women in Utah to 12.7 percent of women in Washington, DC. The researchers say the disproportionate burden of AUD among women across states in New England, the Midwest, and West, with lower prevalence in southern states, is likely a result of multiple factors, including alcohol taxes and other policies, cultural differences in attitudes towards drinking, persistent stigma towards AUD, and AUD healthcare availability. 

“Women’s estimated burden of alcohol use disorder varied substantially from state to state," says study coauthor Dr. Rachel Sayko Adams, research associate professor of health law, policy & management at BUSPH. “These differences highlight the importance of understanding local needs when shaping prevention efforts and designing treatment programs to be more accessible and responsive to women’s needs.”

Among nearly 14,000 alcohol treatment facilities for adults across the nation, only 58.5 percent offered women-specific programming. Twenty-three states and Puerto Rico had fewer than 10 facilities offering women-specific treatment per 10,000 women with AUD. Most of the treatment facilities in states with a higher estimated prevalence of AUD among women had below-average availability of critical services such as trauma therapy, intimate partner violence support, and transportation assistance. Less than half of all treatment facilities offered telehealth services—an accommodation that could be especially valuable for women who lack reliable transportation or struggle with stigma or other fears of seeking in-person treatment. 

Only 4.6 percent of addiction treatment facilities provided childcare in 2024.

“For many women, lack of childcare is a persistent barrier to AUD treatment, as women are more likely to be the primary caregivers of their children,” says study lead author Sage Feltus, research associate in the Department of Health Law, Policy & Management at BUSPH. “Parenting women may find it difficult to obtain reliable, affordable, and trustworthy childcare in their communities while they participate in lifesaving AUD treatment, and most treatment centers do not provide childcare options. Supporting women's recovery from AUD would mean providing solutions to the childcare barrier and other barriers women face.” 

This insight into women-specific AUD treatment comes amid changing norms of how society views alcohol use among women—now widely accepted and normalized in daily life, despite copious research showing that even moderate amounts of drinking place women at greater risks for developing breast cancer, liver disease, suicidal ideation, and reproductive health complications. In a previous study, the researchers found that women without children by age 35 were at highest risk for binge drinking and AUD, but 35-year-old women with children also remained at an increased risk, perhaps influenced by a proliferation of messaging on social media and in popular culture embraces drinking as a form of stress relief and enjoyment.

“Despite the well-established health risks of drinking, popular culture often presents alcohol as a way for women to celebrate or unwind,” says Dr. Adams. “Women need clear information about alcohol-related health risks and access to treatment that is responsive to their needs.”

The researchers outline several actions that states can take to expand women’s access to tailored AUD treatment, particularly in regions with the greatest need. In addition to incentivizing facilities to provide childcare and telehealth services, they note that states can require health plans to cover alcohol treatment services and medications—perhaps a necessary mandate, as a previous analysis by the researchers found that fewer than half of Medicaid managed care plans provide all AUD medications approved by the Food and Drug Administration. The team also recommends primary care offices and mental health facilities screen and treat for AUD, as women with AUD are more likely to seek treatment for co-occurring mental health conditions at these healthcare facilities more than at an addiction treatment facility.

The study was coauthored by Dr. Katherine Keyes, professor of epidemiology and Susan Lasker Brody Professor of Population Mental Health at Columbia; Dr. Jake Morgan, research assistant professor of health law, policy & management at BUSPH; and Dr. Miriam Harris, primary care addiction specialist at BMC. This research was supported by the NIAAA under Award Number R01AA029821. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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About Boston University School of Public Health 

Founded in 1976, Boston University School of Public Health is one of the top ten ranked schools of public health in the world. It offers master's- and doctoral-level education in public health. The faculty in six departments conduct policy-changing public health research around the world, with the mission of improving the health of populations—especially the disadvantaged, underserved, and vulnerable—locally and globally.

 

Q&A: UW doctoral student on expanding climate models to better capture the complexities of public health




University of Washington






About a decade ago, a group of climate scientists described five scenarios for the future. Called the Shared Socioeconomic Pathways (SSPs), these scenarios suggest how socioeconomic development could evolve in worlds with differing challenges to climate adaptation and mitigation. 

One SSP, “Sustainability,” envisions a collective shift toward green energy, reducing economic inequities and investments in research and development. Another, “Regional Rivalry,” paints a picture of a world riven by nationalism and fighting over resources. In that future, high levels of conflict stifle economic development. Rich countries see slower population growth, while birth rates increase in poorer nations. 

Scientists and policymakers use SSPs to project how today’s choices affect tomorrow’s world. But for complex subjects like public health, these intentionally simple scenarios don’t capture every complexity. Under the SSP “Fossil-Fueled Development,” for example, the world doubles down on fossil fuels, spurring rapid economic growth. That growth, according to the scenario, would spur investments in education and health. But at the same time, increased emissions would degrade the environment, exacerbating health risks.

That description leaves many public health questions unanswered: Would hospital systems be better prepared to handle the increased volume? Could more frequent heat waves lead people to spend more time inside, amplifying mental health burdens? 

Last year, a group of 63 experts in climate change and health met in Vienna to extend the SSPs to better reflect the dynamic nature of public health over the course of the century. Their expanded narratives, published Oct. 5 in The Lancet Planetary Health, provide comprehensive visions of possible population health and health system development and explore how communities might better prepare for shifting future health risks.

Carole Green, a UW doctoral student in environmental and occupational health sciences, attended the workshop and is lead author of the accompanying paper. UW News sat down with Green to talk about where previous climate scenarios fell short, the conference’s work and how we can better prepare to keep each other safe in an uncertain future. 

What are the Shared Socioeconomic Pathways, and how do we use them? 

Carole Green: Shared Socioeconomic Pathways are a narrative framework that can be used in conjunction with pathways of greenhouse gas emissions to project future climate impacts to 2100. The SSPs are basically descriptions of the societal choices that affect the magnitude and pattern of interventions to protect human health and well-being.

The SSPs are essentially five possible alternatives for our future world. These pathways have been expanded to incorporate a wide range of issues of relevance for public health, and have been downscaled to describe what the future might look like in different countries and regions.

SSPs are featured in global processes like United Nations climate conferences, where negotiators come from around the world to debate and agree on approaches to build resilience and sustainability to climate changes. The models help us understand how those choices interact and what the effects might be. 

We also use the SSPs in health research to understand the possible magnitude and geographic pattern of health impacts from climate change over the course of this century. Many projects at UW use future warming levels to analyze things like future wildfire impacts on Washington residents (research done by UW’s Climate Impacts Group). 

What do the SSPs leave out? 

CG: SSPs assume that humans will make socioeconomic changes in the future. The changes described in the pathways originally quantified GDP and population changes. Our work adds complexity, specifically to understand how the future of public health could evolve under these five pathways.

A lot of people are interested in heat waves, for example. Climate modeling alone can capture the planet’s warming, but doesn’t consider issues like how access to hospitals and healthcare could change by 2100. Current heat wave modeling looks at the climate interactions that shape health impacts but don’t explore how concurrent changes in society could interact with climate change to impact people’s well-being. 

Once you added complexity into the SSPs, what changed in your understanding of possible futures? Did you learn anything new or surprising?

CG: We learned that the drivers of health impacts are complex, and many are neither entirely good nor bad. Prioritizing sustainability, mitigation and adaptation will not necessarily lead to the best world for each future health outcome, but it definitely affects the future of health and well-being. Health futures we face globally are not predetermined. Different pathways could lead to vastly different health outcomes, with governance, health-system capacity, resources, equity, and cross-sectoral factors such as water and energy playing critical roles.

For example, under one of the scenarios, people don’t prioritize reducing greenhouse emissions, focusing instead on adapting to the changing climate. Strong investment in technology leads to quite a lot of wealth, which can benefit some health outcomes. But it’s not ideal, because people would also have to spend more time indoors because of the growing heat burden and would have to reduce connection to the outdoors and nature. You really don’t want to live in that scenario.

It’s very much a mix, which is challenging. 

Now that we have these fleshed-out scenarios, what does that allow us to do? 

CG: It allows us to have a more complex understanding of future health risks from climate change. Now we can add a layer of understanding and think about more variables than just warming levels and population numbers. It’s made of a lot of complexities that affect health, and those have their own effects.

In future climate scenarios, what does access to healthcare look like? What is the extent of food insecurity? How are we making sure people have access to clean air and water? When we have some understanding of those interactions, then it can motivate decision-makers to develop appropriate policies. 

What comes next? 

CG: We will apply these narratives to six different countries where there has been limited research using the SSPs. We’re working in Brazil, Senegal, South Africa, India, Vietnam and the Solomon Islands. We’ve started identifying key leads across these countries, where there is quite an appetite for this research. All countries are required to develop national health adaptation plans and to conduct vulnerability and adaptation assessments. They are also interested in modeling future health risks. We want to explore the extent to which the SSP narratives apply in their country’s context. Do they fit? How would they look different? There’s a lot of interest in building on local knowledge and bringing local experts together to talk about possible futures. 

We’re also quantifying specific disease burdens, universal healthcare access, water and sanitation infrastructure and digital health. Some quantifications will look at pairing SSPs with certain warming levels to project impacts. 

Last question: This group — including dozens of the world’s leading experts on climate and health — chose you to write the paper. How did that happen? 

CG: I am definitely not the leading expert in that room, so it was very much an honor to work on this and lead the writing. A lot of it comes from my advisor, Kristie Ebi, who is very supportive of me and my work. That’s been really meaningful. She encouraged me to take this on.

I often tell people that my job is to listen to experts and write down what they say. It was very meaningful to get to make those connections. 

For more information or to reach the researchers, contact Alden Woods at acwoods@uw.edu.

 

Medical device adverse event reports are often incomplete, inaccurate, and delayed



Bulk summary reports often fail to promptly spot potential safety signals Improvements needed to safeguard patients and meet FDA standards



BMJ Group






Permitting medical device manufacturers to submit bulk summary reports of adverse events to the US Food and Drug Administration (FDA), rather than reporting individual cases, often fails to promptly detect potential safety signals, finds a study published by The BMJ today.

 

This is a public health concern, argue the researchers, and they call for immediate improvements to better protect patient safety and meet FDA standards.

 

US regulations require medical device makers to report malfunctions and adverse events to the FDA's Manufacturer And User Facility Device Experience (MAUDE) database within 30 days to inform safety measures, such as product recalls, as part of the postmarket surveillance process.

 

MAUDE requires complete and accurate reporting to be effective, but earlier programs, notably the Alternative Summary Reporting (ASR) programme, let manufacturers submit millions of adverse events as bulk summaries rather than as individual reports in order to “reduce the burden on industry.”

 

Although the FDA ended the ASR programme in 2019 due to concerns that it masked safety signals, similar summary reporting exemptions remain in use, but their accuracy, completeness, and compliance with FDA rules are unclear.

 

To address this, researchers analysed all adverse event summary reports submitted to MAUDE over a six-year period (July 2019 to June 2025) for evidence of incomplete device problem identification, undercounting of adverse events, failure to correctly identify reports as summary reports, and delays in serious adverse event reporting.

 

A total of 6,308 summary reports were submitted to the FDA during the study period containing 159,503 adverse events, mostly involving high risk devices. 

 

Of these, 57% identified no device or use problem, 38% reported insufficient information, 11% were incorrectly identified as non-summary reports, 7% incorrectly listed one event in the ‘number of events’ field, and 55% exceeded the FDA’s 30-day reporting deadline.

 

The researchers acknowledge the inherent limitations of passive adverse event reporting and the lack of publicly available information on the specific requirements governing summary reporting exemptions. 

 

However, they say identifying and correcting the existing flaws highlighted in this study are vital, particularly given that the number of summary reports submitted to the FDA - and the number of adverse events contained within them - more than doubled between 2020 and 2024.

 

“Immediate improvements are needed to better protect patient safety and adhere to transparency principles outlined by the FDA,” they write. “Making serious adverse event reports fully visible and accessible is critical to patient safety.”

 

In a linked editorial, Koji Todaka at Kyushu University Hospital in Japan, says these findings raise concerns about transparency in a system intended to support public scrutiny of medical device safety.

 

To preserve public trust in postmarket surveillance, he says regulators should require accurate and timely summary reporting, standardised device identification, and clear links to registries. He also suggests that researchers integrate spontaneous reports, registries, and linked healthcare data rather than treating any single source as definitive.

 

He also notes that the FDA is currently transitioning to a new Adverse Event Monitoring System (AEMS), designed to consolidate existing reporting systems and publish adverse event reports in real time.

 

“Transparency builds trust, evidence improves safety, and both are essential to effective postmarket surveillance and safer medical devices,” he concludes.