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Tuesday, September 08, 2026

 

Second-hand smoke: 2.7 billion exposed, 767 million of them children, study finds

A third of the world’s population exposed to second-hand smoke.
Copyright Cleared/Canva


By Marta Iraola Iribarren
Published on

Second-hand smoke causes serious health harm, including heart disease, respiratory illness and cancer, and remains a leading cause of preventable death worldwide.

A third of the world’s population is exposed each year to second-hand smoke — also known as passive smoking — which continues to be a major source of illness and mortality among non-smokers.

An estimated 2.71 billion people around the world were exposed to second-hand smoke— a combination of two types of smoke inhaled by non-smokers — in 2023, contributing to 1.66 million deaths. This includes 767 million children under 15, who are especially vulnerable, along with 1.49 billion women.

These new findings come from the Global Burden of Disease (GBD) 2023 study, published in The Lancet Public Health, which estimated second-hand smoke exposure and health impacts across 204 countries and territories between 1990 and 2023.

Need for stronger regulation

Despite the scale of exposure, the study found that approximately 70% of the world’s population is not protected by comprehensive smoke-free laws.

As of 2024, only 79 countries, approximately 70% of them in the Americas, have achieved the highest protection standards of the World Health Organization framework — with all public places completely smoke-free or at least 90% of the population covered by legislation.

The proportion of the global population covered by comprehensive smoke-free legislation has increased from 3% in 2007 to 33% in 2024, now covering 2.6 billion people.

However, the authors noted that while smoke-free policies directly reduce smoke exposure, there is a need for extra measures such as tobacco taxation, marketing bans, plain packaging and cessation programmes.

Regional patterns

The researchers found that the number of people impacted by second-hand smoke exposure remained broadly the same globally, but rose sharply in sub-Saharan Africa, North Africa and the Middle East, which they attributed to population growth.

The exposure prevalence in the Central Europe, Eastern Europe and Central Asia region was 37.7% — higher than the global average of 33.9% — affecting 146 million people.

Most of the countries in Western Europe were included in the “high-income super region,” which showed some of the most significant progress in reducing passive smoking.

Denmark and Norway achieved some of the world's largest reductions since 1990, at -48,8% and -44,3%, respectively.

Broad health impacts

Beyond how many people are exposed, the report found that second-hand smoke accounted for the loss of 44.8 million years of healthy life and continues to be a major contributor to disability and premature death.

While a smoker inhales "mainstream smoke" through the cigarette's filter, non-smokers primarily breathe in sidestream smoke. This is unfiltered and contains higher per-unit concentrations of toxic and carcinogenic compounds than the smoke inhaled by the smoker.

The researchers estimated that second-hand smoke remains a substantial driver of global health loss, particularly through cardiovascular and paediatric respiratory diseases.

Exposure to tobacco smoke was associated with several health conditions, including stroke, lower respiratory infections, chronic obstructive pulmonary disease, asthma, type 2 diabetes and cancers of the trachea, lung and breast.

Wednesday, August 26, 2026

 

Using FDA addiction science, researcher asks: Do salty, high-fat foods act like drugs?





University of Kansas






LAWRENCE — University of Kansas researcher Tera Fazzino is investigating whether “hyperpalatable” foods marketed to Americans — foods formulated with artificially high amounts of fat, salt and carbohydrates — have traits commonly associated with addictive substances. She recently earned a $2.8 million grant from the National Institutes of Health to test the idea using experimental practices standard in the field of regulatory research.

“We’re using methodology that has already been established in the areas of tobacco and drug regulatory science and is required by the U.S. Food and Drug Administration for any testing of nicotine or other tobacco or pharmaceutical products that enter the market,” said Fazzino, associate professor of psychology at KU and director of the Life Span Institute’s Cofrin Logan Center for Addiction Research & Treatment. “We're using methodology that’s already been established with known substances and addictive drugs and is used for screening and surveillance and regulatory efforts. We're applying it to testing the addictive properties of these foods.”

Fazzino and her colleagues will recruit around 168 participants, then provide them with different “potato chip” food stimuli produced in coordination with the Food Innovation Accelerator program at Kansas State University-Olathe. The food stimuli will differ in their formulations, and their formulations won't be known by participants.

“In the lab, they will sample a chip food stimulus,” Fazzino said. “Then they'll answer some questions about what they think about the chips, how much they like them and then complete some behavioral tasks.”

These tasks will help measure the chips’ “reinforcing effects,” said the KU researcher.

“One will be a self-administration task where they will earn chips to eat,” she said. “We chose chips because this type of savory, salty, carb- and/or fat-heavy food is very characteristic of the U.S. food environment. It’s a kind of a nice, initial food stimulus to use that would have pretty broad applicability to the entire food supply.”

The chip study is based on long-established methodology used by FDA regulators to assess “abuse liability,” which the agency defines as “the potential of a substance to result in addiction and be used repeatedly or even sporadically resulting in undesirable effects.”

“Typical abuse-liability paradigms test the addictive properties of a substance by designing an experiment called an acute dose-response paradigm, where they test different concentrations of the drug,” Fazzino said. “The main comparison is what's called a negative control, which has none of the reinforcing characteristics of the substance being tested. So, for example, if we were testing the addictive properties of vaping products for nicotine, the negative control there would be just vapor without the nicotine in it. We’ve designed our paradigm accordingly, and this acute dose-response paradigm is the gold standard for testing the addictive properties of substances.”

Results could help identify specific ingredients or ingredient combinations that boost a food’s reinforcing properties.

“These foods contain combinations of nutrients, such as fat and sodium or carbohydrates and sodium, at levels that are uncommon in nature,” Fazzino said. “If you remove one of those key nutrients, the food should become less reinforcing.”

The KU researcher said her findings might inform regulators and policymakers, not just fellow scholars.

“The grant was written in a way that we could be able to provide direct evidence to the FDA about the abuse liability of these food stimuli, with the intention of informing potential regulatory action,” she said.

Fazzino recently published findings into how the tobacco industry used practices from cigarette sales to formulate and market hyperpalatable foods in the U.S. and globally in the 1980s and 1990s, with a legacy of negative consequences public health. She said she hopes her new research could spur U.S. policymakers, who she said lag behind regulators in other parts of the world.

“South America is leading the way,” Fazzino said. “Countries like Colombia and Chile have been very proactive in enacting regulatory action to protect their populations from these foods and to prevent these foods from taking over their food supplies. That’s included bans on marketing, especially to children. That has also included really strong, very clear black warning labels with white letters indicating this is ultra-processed or this is unhealthy in some way, and taxation on certain products.”

The NIH grant will enable hiring of a postdoctoral researcher dedicated to the project, fund work by graduate students, and give research and training opportunities to KU undergraduates.

“It's funding not only the study, but student trainees,” Fazzino said. “We have a new postdoc who just joined us. We have research coordinators who will all get state-of-the-art training and experience working on this study. This is really on the forefront of addiction science.”

 

Early nicotine vapor exposure increases nicotine seeking later in life, UTEP study finds





University of Texas at El Paso

Early Nicotine Vapor Exposure_01 

image: 

Ian Mendez, Ph.D. (left), associate professor of pharmacy and chair of the Department of Pharmaceutical Sciences at The University of Texas at El Paso, and Liliana Maynez-Anchondo (right), a doctoral student in the UTEP Department of Psychology, are two of the coauthors of a study that found nicotine vaping during adolescence may leave a lasting imprint on the brain’s reward system, driving nicotine-seeking behavior well into adulthood.

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Credit: The University of Texas at El Paso.






EL PASO, Texas (Aug. 26, 2026) – Nicotine vaping during adolescence may leave a lasting imprint on the brain's reward system, driving nicotine-seeking behavior well into adulthood even after long stretches without any exposure, according to new research led by scientists at The University of Texas at El Paso.

The findings, published in the journal Psychopharmacology, come from a study by a UTEP team working across the School of Pharmacy and the Department of Psychology in the College of Liberal Arts.

Using an animal model of e-cigarette use, the researchers tracked reward-seeking behavior from adolescence through late adulthood.

The most striking result came in the study's final phase, the team said, which was conducted in late adulthood. Following a lengthy period of abstinence, subjects exposed to nicotine vapor early in life sought out nicotine significantly more often than those never exposed. The behavior persisted despite the long gap, pointing to durable changes in how the brain responds to nicotine.

"What we found is that the effects of early nicotine vapor exposure don't simply fade with time," said Ian Mendez, Ph.D., associate professor of pharmacy at UTEP, chair of the pharmaceutical sciences department and the study's corresponding author. "Even after an extended period with no nicotine whatsoever, that early exposure was still shaping behavior later in life. That matters enormously for the millions of young people who began vaping as teenagers and are now carrying the habit into adulthood."

A second experiment examined whether nicotine vapor itself would motivate sustained, effortful work. When each delivery required escalating effort, nicotine drove only modest responding. When the effort required was low, subjects clearly favored a port delivering nicotine. The pattern is consistent with earlier findings that nicotine is a comparatively subtle reinforcer, and it illustrates how challenging vaping behavior can be to capture in a pre-clinical model.

The work lands at a moment of sustained concern about youth vaping. E-cigarettes remain the most commonly used nicotine product among American adolescents, according to data from the FDA National Youth Tobacco Survey (NYTS). Nicotine use is the leading preventable cause of disease, death and disability in the United States, yet the cumulative health effects of vaping that begin in the teenage years and continue into adulthood remain poorly understood, the researchers noted.

"Our faculty and students are confronting a public health crisis that reaches into many households,” said José O. Rivera, Pharm.D., founding dean and professor at UTEP's School of Pharmacy. “And they are doing it with the rigor and creativity that define this University.”

The authors note that the study examined only male subjects and call for future work that includes female subjects, citing well-documented sex differences in the mechanisms driving nicotine use disorder. They also recommend that subsequent studies test how the unique additives and metabolites in e-liquids – the materials that are heated and converted into inhalable aerosol by electronic cigarettes and vaping devices – affect the brain and behavior.

The study was supported by a grant from the National Institutes of Health.

About The University of Texas at El Paso

The University of Texas at El Paso is America's leading Hispanic-serving university. Located at the westernmost tip of Texas, where three states and two countries converge along the Rio Grande, 84% of our 26,000 students are Hispanic, and more than half are the first in their families to go to college. With respect to research, UTEP is in the top 5% of universities in America and offers 169 bachelor's, master's and doctoral degree programs at the only open-access, top-tier research university in America.

Saturday, August 22, 2026

Trump ally cashing in on vape firm accused of targeting kids and a brutal junta

Kathleen Culliton
August 20, 2026 
RAW STORY


U.S. President Donald Trump holds a hat after signing an executive order in the Oval Office, at the White House in Washington, D.C., U.S. February 25, 2025. REUTERS/Evelyn Hockstein TPX IMAGES OF THE DAY

A vape distributor accused of illegally peddling nicotine products to kids has found a champion in Washington, D.C., a former ally of President Donald Trump's who is raking in millions as a lobbyist.

His name is Roger Stone.

Mother Jones reported Thursday that Stone has earned more than $4 million as a lobbyist for firms such as vape-distributor Ecto World under the new administration.

"Trump’s return to the White House has been a tremendous boon to Stone, who not long ago was claiming he had been nearly bankrupted by legal fees," Mother Jones reported.

The report describes him as a "conspiracy theorist and political provocateur who was convicted of lying to Congress and witness tampering in the Trump–Russia investigation, sentenced to 40 months in prison, and subsequently pardoned by Trump."

Stone’s lobbying firm Drake Ventures has signed up a slew of clients that include the cryptocurrency investor “Bitcoin Jesus,” indicted last year on federal fraud charges, and the military junta in Myanmar, reportedly paying Stone $50,000 a month.

Crimes against humanity have spiked in the Junta since the military takeover in 2021, the report notes.

As for Ecto World, it stands accused in New York of trying to get people hooked on nicotine.

"New York State Attorney General Letitia James sued Ecto World and other vape companies for illegally distributing, marketing, and selling addictive candy- and fruit-flavored disposable nicotine products," the report states, "many produced in China, targeting sales to children and fueling the youth vaping epidemic."

Thursday, August 20, 2026

How people consume cannabis may signal risk for heavy use and addiction




NYU Langone Health / NYU Grossman School of Medicine




Nearly half of adults in the United States who use cannabis mainly smoke it, but about 1 in 7 use it in nearly every form available, a behavior tied to daily cannabis use and increased addiction risk, a new study shows. 

Cannabis can be consumed through smoking, vaping, eating, or dabbing, a practice in which people heat cannabis concentrates and inhale the vapor. According to recent national survey data, about 43.8 million people in the US ages 12 and older (more than 15 percent) had used cannabis in the past 30 days. 

Led by NYU Langone Health researchers, the study showed that 48 percent mainly smoked, 21 percent both smoked and vaped, 17 percent mainly used edibles, and 14 percent, the “polymodal group,” used cannabis in nearly every form. 

Published online August 8 in the journal Addictive Behaviors, the work showed that about half of the polymodal group used cannabis every day. By comparison, 28 percent of those who mostly smoked, 31 percent of those who smoked and vaped, and about 13 percent of those who mostly ate edibles used cannabis every day. Cannabis use disorder, the clinical term for related addiction, followed the same pattern, affecting about 67 percent of polymodal users versus 36 percent of those who primarily smoked, 47 percent of those who smoked and vaped, and 15 percent of those who mainly consumed edibles. 

“Our findings suggest that using cannabis in multiple forms may be a red flag for heavier use and symptoms of addiction,” said study lead author Omar El-Shahawy, MD, PhD, MPH, an assistant professor in the Department of Population Health at NYU Grossman School of Medicine. “Asking patients not only whether but how they use cannabis could help clinicians identify when a fuller assessment may be warranted.” 

In the first national study to examine how these methods naturally cluster, the researchers analyzed data from 17,732 adults who reported using cannabis in the past month on the 2022–2023 National Survey on Drug Use and Health. The authors used a statistical approach that grouped participants based on their reported patterns. 

The results also revealed that types of cannabis users varied demographically. Nearly 1 in 3 people in the smoking-and-vaping and polymodal groups were young adults ages 18 to 25, compared with about 1 in 6 of those who mainly smoked. More than half of the edibles group were women, and edibles were especially prevalent among college graduates. Since the researchers did not examine why participants chose particular methods of cannabis use, the reason behind these patterns remains uncertain, said Dr. El-Shahawy. 

Another key finding was that people who smoked cannabis were more likely to also smoke cigarettes, compared with those who mainly vaped or used edibles. Both cigarette and cannabis smoke involve combustion (burning), which can be hard on the lungs, so doing both may add to their overall health risks.

“The strong tie between smoking cannabis and smoking cigarettes is of concern because this subset of people are breathing in a wider range of chemicals via combustion, and their lungs are at risk,” said senior author Joseph J. Palamar, PhD, MPH, a professor in the Department of Population Health at NYU Grossman School of Medicine. 

“Public health messages about cannabis still focus mostly on smoking, but people now use the drug in many different ways,” said Dr. El-Shahawy. “For younger adults, that means talking about the risks of vaping and combining multiple forms, while for people who prefer edibles, the message is to ‘start low and go slow’ because the effects take time to kick in.”

According to Dr. El-Shahawy, the team next plans to examine why people choose one method over another—for example, whether those who favor edibles are using cannabis for pain or sleep. 

The researchers cautioned that the findings rely on the participants’ self-reports of their cannabis use and that some use may have been underreported. In addition, the study could not establish cause and effect. 

Funding for the study was provided by the National Institutes of Health grant R01DA055675. 

In addition to Drs. El-Shahawy and Palamar, NYU Langone researchers involved in the study were Mohsen Abbasi-Kangevari, MD, MPH; Michelle He; and Xiaoying Zheng. Another study co-investigator was Neal Doran, PhD, at the University of California, San Diego. 

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About NYU Langone Health
NYU Langone Health is a fully integrated health system that consistently achieves the best patient outcomes through a rigorous focus on quality that has resulted in some of the lowest mortality rates in the nation. Vizient Inc. has ranked NYU Langone No. 1 out of 118 comprehensive academic medical centers across the nation four years in a row, and it continues to have the most No. 1– and top 10–ranked specialties among medical centers in the United States, according to U.S. News & World Report. NYU Langone offers a comprehensive range of medical services with one high standard of care across seven inpatient locations, its Perlmutter Cancer Center, and more than 330 outpatient locations in the New York City area and Florida. The system also includes two tuition-free medical schools, in Manhattan and on Long Island, and a vast research enterprise

 

Trends in the prevalence and severity of alcohol and cannabis use disorders among US adults



JAMA Psychiatry



About the Study:

 In this cross-sectional study of 186,823 US adults, moderate-to-severe cannabis use disorder prevalence increased from 2021 through 2024 among males and females, while moderate-to-severe alcohol use disorder prevalence remained largely stable. The findings highlight diverging trends in cannabis and alcohol use disorders across age and sex groups.




Corresponding Author: Nora D. Volkow, MD, National Institute on Drug Abuse, National Institutes of Health, 3WFN Room 09D20, MSC 6025, 301 N Stonestreet Ave, Bethesda, MD 20892 (nvolkow@nida.nih.gov).

10.1001/jamapsychiatry.2026.2497

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