Showing posts sorted by relevance for query ROBERT BRENNER. Sort by date Show all posts
Showing posts sorted by relevance for query ROBERT BRENNER. Sort by date Show all posts

Wednesday, April 24, 2019



THE_BRENNER_DEBATE._Agrarian_Class_Structure_
and_Economic_Development_in_Pre-Industrial_Europe

 BOOK PDF


This article was published in ANTIPODE: A RADICAL JOURNAL OF GEOGRAPHY, 26,4,(1994):351-76.
J.M. BLAUT University of Illinois at Chicago
Euro-Marxism
Robert Brenner is a Marxist, a follower of one tradition in Marxism that is as diffusionist, as Eurocentric, as most conservative positions. I cannot here offer an explanation for this curious phenomenon: a tradition within one of the most egalitarian of all socio-political doctrines yet a tradition which, nonetheless, believes in the historical superiority (or priority) of one community of humans, Europeans, over another, non-Europeans. Eurocentric Marxists are not racist, nor even prejudiced, although most of them believe that Europeans have always been the leaders in the forward march of history; that Europe is the fountainhead of civilization, the main source of innovative social change. For these scholars, the origins of capitalism are European. Capitalism's further development consisted of an internally generated process of improvement within its classic homeland, the European world. The impact of capitalism on the rest of the world has been, on balance, progressive. Colonialism and (today) neocolonialism are not significant for capitalism, are rather a marginal process, a temporary aberration or diversion or side-show, not a vital need of the system as a whole, which evolves in response to internal laws of motion.

This is the accepted version of Anievas, Alexander and Nisancioglu, Kerem (2013) What’s at Stake in the Transition Debate? Rethinking the Origins of Capitalism and the ‘Rise of the West’ Millennium: Journal of International Studies Vol. 42 (1), 78-102. Published version available from Sage at: http://journals.sagepub.com/doi/10.1177/0305829813497823Accepted version downloaded from SOAS Research Online: http://eprints.soas.ac.uk/20673/



Ricardo Duchesne*
University of New Brunswick, Saint John, P.O. Box 5050, Saint John, New Brunswick, E2L 4L5, Canada

Received 20 September 1998; accepted 23 July 1999


The Brenner Debate


The Dobb-Sweezy debate is often considered an intra-Marxist debate insofar as the questions and issues that were posed during it were mostly of interest to those already convinced of, or working within the Marxist theoretical tradition of historiography. The discussion charted below, “the Brenner Debate,” discusses many of the same issues, and its eponymous exponent Robert Brenner, argues indeed from a Marxist informed theoretical position. Nonetheless, the central issues in this debate were much more wide-ranging owing in part to the focus of the debate on long-term economic development in Europe. This pulled historians from various traditions into discussing the inherent orthodoxy of ‘the demographic approach’ for this problem. It is the strength of Brenner’s position, and its significance for historically informed theory that provided the groundwork for ‘Political Marxism’ (what was originally an epithet coined by Guy Bois in the contribution below, and later reclaimed in a positive sense by Ellen Meiksins Wood (1981)).

INTRODUCTION
I suppose most people who got their Marxist education in Marxist parties share certain basic assumptions about how First World economic and political hegemony over the so-called Third World has been achieved. It was a function of economic exploitation going back to the discovery of the New World and the several hundred years of advantage this gave the First World, as it expanded its control over countries to the East as well. Gold and silver mined by indigenous peoples, colonial plantations, disruption of local handicrafts in places like India all worked together to give nascent capitalist institutions in Europe the "supercharging" they needed to leapfrog over other countries where similar institutions were also gestating.
So I was surprised, if not shocked, to discover that Robert Brenner, a leader of the left-wing American group Solidarity, wrote a series of articles in the 1970s denying such connections. Brenner's critique was directed against a group of thinkers who, like Paul Sweezy, viewed themselves as operating in the Marxist tradition, and others, like Andre Gunder Frank, who rejected Marxism altogether. What they all had in common was a perspective that development in the core countries is a cause of underdevelopment in the so-called periphery. The prosperity and global power of nations like the United States was a function of the poverty and weakness of countries like Vietnam, Nicaragua and Angola.
But in Brenner's words (New Left Review, 104, 1977), these thinkers "move too quickly from the proposition that capitalism is bound up with, and supportive of, continuing underdevelopment in large parts of the world, to the conclusion not only that the rise of underdevelopment is inherent in the extension of the world division of labour through capitalist expansion, but also that the 'development of underdevelopment' is an indispensable condition for capitalist development itself."
I will argue that the 'development of underdevelopment' is indeed an indispensable condition for capitalist development itself, but before doing so it will be necessary to provide some historical background into Marxist thinking on these questions. Since Brenner claims to be defending classical Marxism against newfangled, neo-Smithian deviations, it would be useful to now review what Marx and Marxists have written.



by RP BRENNER - ‎2001 - ‎
Keywords: Brenner debate, economic development, Netherlands agrarian ... standing debate on the transition to capitalism, with respect to earlier stages of.
In the most recent phase of the discussion on the historical conditions for economic development, or the transition from feudalism to capitalism, the town-dominated Low Countries have been neglected, because the focus has been to such a large extent on agrarian conditions and agrarian transformations. This article seeks to make use of the cases of the medieval and early modern Northern and Southern Netherlands, the most highly urbanized and commercialized regions in Europe, to show that the rise of towns and the expansion of exchange cannot in themselves bring about economic development, because they cannot bring about the requisite transformation of agrarian social-property relations. In the non-maritime Southern Netherlands, a peasant-based economy led to economic involution. In the maritime Northern Netherlands, the transformation of peasants into market-dependent farmers created the basis for economic development.

Journal of Agrarian Change, Vol. 2 No. 1, January 2002, pp. 88–95. Charles Post © Blackwell Publishers Ltd, Henry Bernstein and Terence J. Byres 2002.

SUGGESTIONS AND DEBATES
 Capitalism, Merchants and Bourgeois Revolution:Reflections on the Brenner Debate and its Sequel 
ELLEN MEIKSINS WOOD
 The "Brenner Debate" launched by Past and Present in 1976 was about "agrarian class structure and economic development in pre-industrial Europe". Robert Brenner's recent book, Merchants and Revolution, has opened a new front in the debate by introducing merchants and "commercial change" into the equation.1 Although the book's massive Postscript carefully situates Brenner's analysis of commercial development in the context of his earlier account of the agrarian transition from feudalism to capitalism, this is unlikely to foreclose debate about how, or even whether, his more recent argument about the role of merchants in the English revolution can be squared with the original.Brenner thesis. What is at issue here is not just divergent interpretations of historical evidence but larger differences about the nature of capitalism. The following argument has more to do with the latter than with the former, and it will be concerned with Brenner's work and the debates surrounding it not just for their own sake but for what they reveal about the dominant conceptions of capitalism, in Marxist and non-Marxist histories alike.

 Comments on the Brenner–Wood Exchangeon the Low Countries 
CHARLES POST 

The exchange between Brenner and Wood on the Low Countries in the early modern period raises a number of theoretical and historical issues relating to the conditions for the emergence of capitalist social-property relations and their unique historical laws of motion. This contribution focuses on three issues raised in the Brenner–Wood exchange: the conditions under which rural household producers become subject to ‘market coercion’, the potential for ecological crisis to restructure agricultural production, and the relative role of foreign trade and the transformation of domestic, rural class relations to capitalist industrialization. Keywords: Brenner debate, economic development, 




Is there anything to defend in Political Marxism?


At the conclusion of their article, “In Defense of Political Marxism” (International Socialist Review #90, July 2013), Jonah Birch and Paul Heideman note that: “Advocates of Political Marxism like Robert Brenner, Ellen Meiksins Wood, and Charles Post share a tremendous amount with their critics like Jairus Banaji, Neil Davidson, and Ashley Smith in their common perspective on the necessity for revolutionary socialism from below.”1 It is certainly true that members of Solidarity like Brenner and Post are revolutionaries who have made significant contributions to issues of central importance to the Left, many of which are perfectly compatible with the International Socialist tradition.2 Others from the same organization, like John Eric Marot, have critically engaged with aspects of that tradition such as our attitude to the Left Opposition, but in comradely ways that helped to develop our collective understanding.3 
One of the difficulties with Political Marxism, however, is its political indeterminacy. Not all proponents are revolutionaries: Wood inhabits a position close to that of Ralph Miliband and his successors on the editorial board of The Socialist Register, although she too has made important theoretical contributions, above all in relation to the nature of democracy under capitalism. Other Political Marxists, however, inhabit an almost exclusively scholastic universe in which ferocious declarations of adherence to what they take to be the Marxist method are completely detached from any socialist practice, resulting in a kind of academic sectarianism.
The uneven relationship of Political Marxists to socialist practice is not however the main problem with this theoretical tendency. If it was simply a provocative historical argument about the emergence of capitalism then it would have no necessary implications for contemporary politics—and several Political Marxists have produced historical works which contain important findings independent of how persuasive or otherwise one finds the Brenner Thesis, notably Brenner’s own Merchants and Revolution and Post’s The American Road to Capitalism


Monday, March 30, 2020

THE BRENNER DEBATE. REDUX

https://plawiuk.blogspot.com/search?q=THE+BRENNER+DEBATE.


The Brenner Debate: Agrarian Class Structure and Economic Development in Pre-Industrial Europe. Edited by T.H. Aston and C.H.E. Philpin (Cambridge, London, New York: Cambridge University Press, ‘Past and Present Publications’, 1985, viii + 341 pp.) PDF


Agrarian Class Structure and Economic Development in Pre-Industrial Europe*
ROBERT BRENNER 

This is the accepted version of Anievas, Alexander and Nisancioglu, Kerem (2013)
 What’s at Stake in the Transition Debate? Rethinking the Origins of Capitalism and the ‘Rise of the West’ Millennium: Journal of International Studies Vol. 42 (1), 78-102. Published version available from Sage at: http://journals.sagepub.com/doi/10.1177/0305829813497823 Accepted version downloaded from SOAS Research Online: http://eprints.soas.ac.uk/20673/

The Transition Debate Today: 
A Review of The Origin of Capitalism in England, 1400–1600 
by Spencer Dimmock
Article (PDF Available) in Historical Materialism 26(2) · September 2018 with 543 Reads 
DOI: 10.1163/1569206X-00001701 Cite this publication

Abstract
Spencer Dimmock has produced a convincing restatement, defence and update of Robert Brenner's influential work on the origin of capitalism in England. The book productively engages with many Marxist and non-Marxist critics of the so-called 'Brenner Thesis', and presents fresh secondary and primary evidence in favour of it. This review sketches the theoretical background of Brenner's intervention, summarises Dimmock's take on Brenner, and comments on a few notable contemporary critiques of Brenner's general framework which are not explicitly engaged with by Dimmock.


Journal of Agrarian Change, Vol. 1 No. 2, April 2001, pp. 169–241. 
The Low Countries in the Transition to Capitalism
ROBERT P. BRENNER
In the most recent phase of the discussion on the historical conditions for
economic development, or the transition from feudalism to capitalism, the
town-dominated Low Countries have been neglected, because the focus has
been to such a large extent on agrarian conditions and agrarian transformations. This article seeks to make use of the cases of the medieval and early
modern Northern and Southern Netherlands, the most highly urbanized
and commercialized regions in Europe, to show that the rise of towns and the
expansion of exchange cannot in themselves bring about economic development, because they cannot bring about the requisite transformation of agrarian
social-property relations. In the non-maritime Southern Netherlands, a
peasant-based economy led to economic involution. In the maritime Northern
Netherlands, the transformation of peasants into market-dependent farmers
created the basis for economic development.
Keywords: Brenner debate, economic devel


Journal of Agrarian Change, Vol. 2 No. 1, January 2002, pp. 88–95. 
Charles Post © Blackwell Publishers Ltd, Henry Bernstein and Terence J. Byres 2002.
 Comments on the Brenner–Wood Exchange on the Low Countries 
CHARLES POST The exchange between Brenner and Wood on the Low Countries in the early modern period raises a number of theoretical and historical issues relating to the conditions for the emergence of capitalist social-property relations and their unique historical laws of motion. This contribution focuses on three issues raised in the Brenner–Wood exchange: the conditions under which rural household producers become subject to ‘market coercion’, the potential for ecological crisis to restructure agricultural production, and the relative role of foreign trade and the transformation of domestic, rural class relations to capitalist industrialization.


Wednesday, April 24, 2019

THE BRENNER DEBATE EXPLAINED 

 The Brenner Debate The agricultural revolution Sixteenth- and seventeenth-century England witnessed an agricultural revolution which involved massive changes in land tenure, the organization of production on farms, the techniques employed in farming, and the productivity of agriculture. Thus the sixteenth century represented a sharp change in English rural life: the emergence of the capitalist farm in place of small-scale peasant cultivation, the intensification of market relations, increase in population, and eventual breakthrough to capitalist development in town and country. The social consequences of this revolution were massive as well: smallholding peasant farming gave way to larger capitalist farms; hundreds of thousands of displaced peasants were rapidly plunged into conditions of day labor, first in farming and then in manufacture in towns and cities; higher farm productivity permitted more rapid urbanization and the growth of an urban, commercialized economy; and higher real incomes provided higher levels of demand for finished goods which stimulated industrial development. Thus the agricultural revolution was the necessary prelude to the industrial revolution in England. [1] “It was the growth of agricultural productivity, rooted in the transformation of agrarian class or property relations, which allowed the English economy to embark upon a path of development foreclosed to its Continental neighbours. This path was distinguished by continuing industrialization and overall economic growth through the period when `general crisis' gripped the other European economies” (Brenner 1982:110). It was indeed, in the last analysis, an agricultural revolution, based on the emergence of capitalist class relations in the countryside which made it possible for England to become the first nation to experience industrialization [through higher levels of grain productivity and higher income to stimulate demand for industrial goods]. (Brenner 1976:68) This process poses at least two problems for historical explanation. First is an historical question: why did breakthrough occur in England in the sixteenth century and not the fifteenth or the nineteenth? And the second is geographic: why did this process of agricultural development occur in England but not on the Continent? In particular, why did agrarian life in the French countryside remain relatively unchanged throughout this period? And why did eastern Europe slide into a “second feudalism”? [2] A variety of explanations have been advanced for these developments. Some economic historians (e.g., M. M. Postan and Emmanuel Le Roy Ladurie) have maintained that the cause of this process of change was an autonomous increase in either population or commerce or both. Robert Brenner argues, however, that these explanations are inadequate, since these large-scale factors affected the whole of Western Europe, while capitalist breakthrough occurred only in Britain. Brenner holds that the determining factor is the particular character of social-property relations in different regions of Europe (particularly the conditions of land-tenure and associated forms of surplus extraction), the interests and incentives which these relations impose on the various actors, and the relative power of the classes defined by those relations in particular regions. Brenner's explanation of these developments is thus based on “micro-class analysis” of the agrarian relations of particular regions of Europe. The processes of agricultural modernization unavoidably favored some class interests and harmed others. Capitalist agriculture required larger units of production (farms); the application of larger quantities of capital goods to agriculture; higher levels of education and scientific knowledge; etc. All of this required expropriation of small holders and destruction of traditional communal forms of agrarian relations. Whose interests would be served by these changes? Higher agricultural productivity would result; but the new agrarian relations would be ones which would pump the greater product out of the control of the producer and into elite classes and larger urban concentrations. Consequently, these changes did not favor peasant community interests, in the medium run at least. It is Brenner's view that in those regions of Europe where peasant societies were best able to defend traditional arrangements--favorable rent levels, communal control of land, and patterns of small holding--those arrangements persisted for centuries. In areas where peasants had been substantially deprived of tradition, organization, and power of resistance, capitalist agriculture was able (through an enlightened gentry and budding bourgeoisie) to restructure agrarian relations in the direction of profitable, scientific, rational (capitalist) agriculture. Hypertext Book | UnderstandingSociety | Daniel Little <!--[if lt IE 6]> <![endif]

Saturday, January 2, 2010

The Brenner debate revisited


One of the defining controversies in the field of economic history in the past 35 years is the Brenner debate.  Robert Brenner published "Agrarian Class Structure and Economic Development in Pre-Industrial Europe" in Past and Present in 1976 (link) and "The Agrarian Roots of European Capitalism" in 1982.  In between these publications (and following) there was a rush of substantive responses from leading economic historians, including M. M. Postan and Emmanuel Le Roy Ladurie.  (Many of the most significant articles are collected in Aston and Philpin's The Brenner Debate: Agrarian Class Structure and Economic Development in Pre-industrial Europe.)  Brenner's theories injected important new impetus into the old question: what led to the advent of capitalism?  (Maurice Dobb had stimulated a similar burst of scholarship on this topic with his 1963 Studies In The Development Of Capitalism (link).  Brenner's discussion of the Dobb debate can be found in his essay, "Dobb on the transition from feudalism to capitalism" here.)

The core issue of the debate is large and important: what were the social factors that brought about the major economic transformations of the European economy since the decline of feudalism?  Feudalism was taken to be a stagnant economic system; but in the sixteenth century things began to change.  There was something of an agricultural revolution in England, with technological innovation, changes of cropping systems, and significant increase in land productivity.  There were the beginnings of manufacture, leading eventually to water- and steam-powered machines.  There was a population shift from the countryside to towns and cities.  There was industrial revolution.  (Marx describes much of this process in Capital; here's an earlier post of his concept of "primitive accumulation.")  So what were the large social factors that caused this widespread process of social and economic change?  What propelled these dramatic changes of economic structure?

The great economic historian M. M. Postan offered a simple theory: “Behind most economic trends in the middle ages, above all behind the advancing and retreating land settlement, it is possible to discern the inexorable effects of rising and declining population” (Medieval Economy and Society: An Economic History of Britain in the Middle Ages, p. 72).  Against this view, Brenner writes: "Under different property structures and different balances of power, similar demographic or commercial trends, with their associated patterns of factor prices, presented very different opportunities and dangers and thus evoked disparate responses, with diverse consequences for the economy as a whole. Indeed, . . . under different property structures and balances of class forces . . . precisely the same demographic and commercial trends yielded widely divergent results" (Brenner 1982:16-17).  Key to Brenner's argument is the fact that agricultural change was substantially different in England and France; so he insists that an adequate causal explanation must identify a factor that varies similarly.

From the distance of several decades, the dividing lines of the Brenner debate are pretty clear.  One school of thought (Postan, Ladurie) attempts to explain the economic transformations described here in terms of facts about population, while the other (Brenner's) argues that the central causal factors have to do with social institutions (social-property relations and institutions of political power). The demographic theory focuses its attention on the factors that influenced population growth, including disease; the social institutions theory focuses attention on the institutional framework within which economic actors (lords, peasants, capitalist farmers) pursue their goals.  The one is akin to a biological or ecological theory, emphasizing common and universal demographic forces; the other is a social theory, emphasizing contingency and variation across social space.

A voice that doesn't come into the debate directly but that is highly relevant is that of Douglass North. His book (with Robert Paul Thomas), The Rise of the Western World: A New Economic History, offers a theory of modern economic development that falls within the category of "social institutional theory" rather than demographic theory.  But whereas Brenner finds primary causal importance in the institutions that define local class relations (a Marxian idea), North argues that property relations that create the right kinds of incentives will stimulate rapid economic growth (a Smithian idea). And North finds that this is the innovation that took place in England in the early modern period.  It was the creation of capitalist property relations that stimulated economic growth.

This schematic representation of the strands of argument in the Brenner debate suggests competing causal diagrams:
  • population growth => economic activity => sustained economic growth (Postan)
  • weak peasant farmers, strong capitalist farmers => enclosure and farming innovations => rapid agricultural growth (Brenner)
  • enhanced protections of property rights => incentive for profitable activity => sustained economic growth (North)
But it seems clear in hindsight that these are false dichotomies. We aren't forced to choose: Malthus, Marx, or Smith.  Economic development is not caused by a single dominant factor -- a point that Guy Bois embraces in his essay (Aston and Philpin, 117).  Rather, all these factors were in play in European economic development -- and several others as well.  (For example, Ken Pomeranz introduces the exploitation of the natural resources, energy sources, and forced labor of the Americas in his account of the economic growth of Western Europe (The Great Divergence: China, Europe, and the Making of the Modern World Economy).  And I suppose that it would be possible to make a climate-change argument for this period of change as well.)  Moreover, each large factor (population, prices, property relations) itself is the complex result of a number of great factors -- including the others on the list.  So we shouldn't expect simple causal diagrams of large outcomes like sustained economic growth.

Not all the heat of this debate derives from a polemic between a neo-Marxist theorist and the Malthusians; there is also a significant disagreement between Brenner and another important Marxist economic historian, Guy Bois.  Bois' Crisis of Feudalism appeared in 1976 -- the same year as Brenner's first paper in the debate.  The crisis to which Bois refers is an analogy with a classic Marxist claim about capitalism: where Marx discerned a crisis in capitalism deriving from the falling rate of profit, Bois found a crisis in feudalism deriving from a falling rate of feudal levy.  (Here is an interesting review by Chris Harman of another of Bois' books, The Transformation of the Year One Thousand: The Village of Lournard from Antiquity to Feudalism.)  Bois criticizes Brenner's account for being excessively theory-driven.  He argues that Brenner begins with a commitment to class struggle as a fundamental explanation, and then forces the facts of French and English rural life into this framework.  Better, he argues, to let the complexity of the historical situations emerge through careful evaluation of the evidence.  "Brenner's thought is, in fact, arranged around a single principle: theoretical generalization always precedes direct examination of historical source material" (Aston and Philpin, 110).  And Bois argues that the evidence will suggest that it is the declining feudal levy rather than the capacity for resistance by French peasants that best explains the course of events in France.

In short, one important consequence of the Brenner debate was the renewed focus it placed on the question of social causation.  Brenner and the other participants expended a great deal of effort in developing theories of the causal mechanisms that led to economic change in this period.  And in hindsight, it appears that a lot of the energy in the debates stemmed from the false presupposition that it should be possible to identify a single master factor that explained these large changes in economic development.  But this no longer seems supportable.  Rather, historians are now much more willing to recognize the plurality of causes at work and the geographical differentiation that is inherent in almost every large historical process.  So the advice that Bois extends -- don't let your large theory get in the way of detailed historical research -- appears to be good counsel.

A web-based text for the philosophy of social sciences



A WEB-BASED RESOURCE
The philosophy of social sciences raises a series of foundational questions having to do with how we can arrive at empirically and theoretically supported understandings of social and individual behavior. What is involved in explaining social outcomes and patterns? How do agents cause outcomes? What roles do social entities such as structures, organizations, or moral systems play in social causation?
My blog, UnderstandingSociety, addresses a series of topics in the philosophy of social science. What is involved in "understanding society"? The blog is an experiment in writing a book, one idea at a time. In order to provide a bit more coherence for the series of postings, I've organized a series of threads that link together the postings relevant to a particular topic. These can be looked at as virtual "chapters". This list of topics and readings can serve as the core of a semester-long discussion of the difficult philosophical issues that arise in the human sciences. It roughly parallels the topics I cover in the course I teach in the philosophy of social science at the University of Michigan.
Look at this web document as a web-based, dynamic monograph on the philosophy of social science; and look at this list of threads as one possible route through some foundational issues in the philosophy and methodology of social science.



© Daniel Little 2011


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Thursday, November 14, 2024

 

Robert Brenner: ‘The most extreme characteristics of US imperialism come from its relationship to the indigenous population’


Published 

Robert Brenner

[Editor's note: The following is an edited transcript of the speech given by Robert Brenner on the “Imperialism(s) today” panel at the “ Boris Kagarlitsky and the challenges of the left today” online conference, which was organised by the Boris Kagarlitsky International Solidarity Campaign on October 8. Brenner is a US economic historian, professor emeritus of history and director of the Center for Social Theory and Comparative History at UCLA, and editor of the socialist journal Against the Current. Transcripts and video recordings of other speeches given at the conference can be found at the campaign website freeboris.info, from where the below is republished.]

The topic I was assigned is imperialism today. My argument is that the theory of imperialism put forward by Vladimir Lenin in 1916 to end World War I remains, if properly qualified, the best point of departure for understanding imperialism today.

Lenin’s theory was profoundly historical, and this is its strength. I think that is why this theory, his little pamphlet, constantly criticized and surpassed, remains a very good place to start for understanding imperialism today. It was designed to understand the operation of the international capitalist system at a certain phase of its development, namely the first decades of the 20th century. Still, I would say that it provides a surprisingly powerful conceptual framework, addressing not only Lenin’s epoch, but our own. It is about understanding the system as a whole, and that is its strength.

Lenin famously defined the capitalist system at the moment of imperialism that he was looking at in terms of five defining traits that emerged as an expression of international competition or rivalry. Looking at this material historically, we can see that what Lenin is talking about is a division of the world between one country that develops earlier, which we might call a hegemon, and those that develop later. The characteristics of each have to do with their functional requirements for reproducing international leadership on the one hand and challenging that leadership on the other.

The first go round of this system is in the late 19th-early 20th with Britain as the hegemon and the United States, Germany and Japan following behind. Later in the 20th-early 21st century the advanced capitalist countries include Germany, Japan and East Asia, with the United States as the hegemon.

That is the basic picture that we get from Lenin, with one further very important qualification. Lenin is talking about inter-capitalist relations among advanced capitalist countries. Equally important from the standpoint of the picture that we want to draw is that the agents within both these frameworks, late 19th-early 20th and 20th-early 21st century, are further defined by their relationship with the “indigenous population”.

A hugely important determinant of the form of development is its relationship to the underlying population. It is not just an imperial power but a settler imperial power. The most extreme characteristics of US imperialism come from the relationship to the indigenous population and its destruction and displacement.

The institutional arrangements that we are talking about are also forged, in part, from international rivalry. Here you have the earlier developers versus the later developers, with an important distinction between the two based on the vicious military political character of the advanced capitalist countries. You cannot understand the global regime without grasping that difference.

What I want to do is take Lenin’s theory of imperialism and apply it to the post-World War II world, hopefully bringing it up to our own time by revealing the basic outcome of the fight for international hegemony. This international rivalry imprints itself on both leaders and followers.

Lenin talked about concentration of production and capital, the merging of bank and industrial capital, trade production, the domestic market, the formation of international monopolies and colonies. What you can see here is that you have a field of natural selection. Surviving through this capitalist competition is the road in which later developers travel through these ever more elaborate set of institutional arrangements. That is true for the hegemon as well as for those countries that follow.

From the standpoint of the leader, the hegemon, the opportunity was there to advance by trade and foreign direct investment without that massive set of institutional arrangements, often relying on the institutions that were underlyingly created or produced in what became the colonized world, for example, in Latin America. On the one hand is the set of institutional arrangements designed to catch up, challenge and reproduce the hegemony. But these are also arrangements that weaken the older hegemon.

So with that in mind, I want to take the story to the postwar world and the second round of what I am talking about, which would be US hegemony. I am going to have to only briefly outline a great deal of what needs to be said, but I hope I can bring out the important points.

After World War II, US hegemony emerged and was totally dominant in every sphere. It had the power to impose its will across the board. It was able to take the form of hegemony that the British exercised in the late 19th century vis a vis the US, Germany and Japan, and impose it on the rest of the world in a very extreme form.

While international diplomacy and war was in the hands of the US hegemon, its power also created conditions for the rapid development in those follower countries most agile in transforming property relations to develop. Not every country could “play” the game. The successful followership “players” were countries that could constitute capitalist social property relations, what Karl Marx characterized as primitive accumulation.

Probably without the background of the Cold War, without the pressures to confront the Soviet Union, the US would not have had the motivation to see to the economic development of its own allies. But that in turn led to a problem: the flip side of this transformation opened the door to the decline of the hegemon. The advantage of coming early to development turned bit by bit to a disadvantage, especially given the US role of being the international policeman. The division of functions taken on by the hegemon threatened to leave the hegemon in the lurch.

This was the story of the first part of the post-war period, where you have rapid development on the part of the later developing Japanese, Germans and then East Asians. This is the dilemma that is imposed by the structure. It works too well for the hegemon and for the followers, because the hegemon finds itself ever less able to rival the followers. What we find is that starting in the 1970s, and revving up in the ’80s, is a reshaping of international institutions to enable the hegemon to function without being eclipsed. In my opinion it is quite a spectacular adjustment that leaves US hegemony even more entrenched than before.

I think this picture explains early 21st century developments. But where does Russia fit into this picture?

The Russian case is one of extremely late development burdened with non-capitalist institutions, so it is necessary for this particularly non-capitalist formation to devise a way to catch up in international competition. As a result, it is a very cramped, politically dependent form of development.

I would say that the way to see contemporary Russia is that you have a late developer without having much in the way of fully developed capitalist institutions, so it has to use political instrumentalities to catch up.

In this sense, Vladimir Putin cannot simply adopt a set of capitalist institutions and therefore must forget the classical development road. He is consequently driven toward a politically-driven development with warfare at its center.

The invasion of Ukraine in 2022 is an artificial attempt to solve the problem of backwardness through a particularly backward means.

It is not particularly surprising that it is not successful. To me, it is leading inexorably to a domestic crisis, which will most likely lead to hypertrophy of the same form rather than transformation.

Sunday, June 02, 2024

  

Personalized phage therapy heals resistant wounds-squeaks makes full recovery




THE HEBREW UNIVERSITY OF JERUSALEM
Squeaks 

IMAGE: 

RELAXING AFTER FULL RECOVERY

view more 

CREDIT: MILAT AND LARRY BERKLEY



A new study demonstrates an advance in treating antibiotic-resistant infections in animals through personalized phage therapy. The treatment combined a specific anti-P. aeruginosa phage applied topically with ceftazidime administered intramuscularly, resulting in the complete healing of a persistent surgical wound after fourteen weeks. This highlights the potential of phage therapy as a practical and effective solution for antibiotic-resistant infections in veterinary practice, with implications for human medicine as well.

 

Link to pictures: https://drive.google.com/drive/folders/12ntfvgd_ZdpEYtMsgkZRjS9vB89ps5XM?usp=sharing

A new study led by Prof. Ronen Hazan and his team, from the Faculty of Dental Medicine at the Hebrew University of Jerusalem, in collaboration with the team of Vet Holim, JVMV -Veterinary medical center in Kiryat -Anavim, Israel, has shown an advance in the treatment of antibiotic-resistant infections in animals. This research, focusing on a five-year-old Siamese cat Squeaks  with a multidrug-resistant Pseudomonas aeruginosa infection post-arthrodesis surgery, marks the first published documented application of personalized phage therapy in veterinary medicine.

Squeaks, initially treated at the JVMV for injuries sustained from a high-rise fall, developed a severe infection in the right hind leg following multiple surgeries. This infection persisted despite various antibiotic treatments over four months. Facing a potential implant-replacement surgery, the team turned to the new treatment which involved a meticulously designed combination of a specific anti-P. aeruginosa phage, a virus that kills bacteria, applied topically to the surgical wound and ceftazidime administered intramuscularly. Moreover, the owners of the cat, after short demonstration, provides most of the treatment doses of phages and antibiotics at their home.

The integration of phage therapy with antibiotics was aimed at targeting the pathogen effectively and directly at the site of infection, leveraging the phage’s ability to be applied topically, which simplifies administration and maximizes its concentration at the infection site. This approach allowed the surgical wound, which had remained open for five months, to fully heal after to fourteen weeks of treatment.

The successful outcome of this case underscores the critical need for novel therapeutics like phage therapy to address the growing concern of antibiotic-resistant infections, which affect up to 8.5% of surgical sites following orthopedic surgeries in companion animals. These infections not only pose significant health risks to the animals but also increase the morbidity, mortality, and costs associated with these procedures.

Recent studies suggest that phage therapy, already showing high success rates in human medicine for treating orthopedic infections and chronically infected wounds, can offer a promising solution for similar issues in veterinary practice. Moreover, the successful treatment of this cat by its owners at home highlights the practicality and efficacy of personalized phage therapy, which could be extended to treat other pets facing similar antimicrobial resistance challenges.

Interestingly, opposite to common situations, this case was performed on an animal based on the team's insights from treating humans first.

The positive reception from veterinarians and pet owners regarding phage therapy points to a growing awareness and acceptance of this treatment option. As the new treatment continues to be explored in veterinary settings, it not only improves the health and well-being of pets but also offers valuable data that contribute to the broader application of phage therapy in both animals and humans. This bridging of data can enhance treatment protocols and outcomes across a variety of bacterial infections, potentially changing the landscape of infection treatment in both veterinary and human medicine.

Phage therapy: In-depth discussion on ethical considerations and regulatory landscape at upcoming European conference “Targeting Phage Therapy 2024”





MITOCHONDRIA-MICROBIOTA TASK FORCE

Ms. Barbara Brenner, speaker at Targeting Phage Therapy 2024 

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BARBARA BRENNER, A LEGAL EXPERT IN MEDICAL LAW AND HUMAN RIGHTS, WILL DELIVER A TALK TITLED "REGULATORY RESTRICTIONS VS. HUMAN RIGHTS, THE HIPPOCRATIC OATH, AND THE FREEDOM OF THERAPY – THE LEGAL ASPECT OF PHAGE THERAPY" AT TARGETING PHAGE THERAPY ON JUNE 20-21, 2024

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CREDIT: TARGETING PHAGE THERAPY




The 7th World Conference on Targeting Phage Therapy 2024 is set to take place on June 20-21 at the Corinthia Palace in Malta, welcoming over 150 attendees from 30 countries and featuring more than 32 communications. This annual event showcases the latest advancements in phage research and therapy, emphasizing how these developments could revolutionize healthcare practices globally.

The Ethical Considerations and Regulatory Landscape of Phage Therapy will be highlighted

Targeting Phage Therapy 2024 will include a dedicated session on the ethical and regulatory aspects of phage therapy, particularly in Europe. Barbara Brenner, a legal expert in medical law and human rights, will deliver a talk titled "Regulatory Restrictions vs. Human Rights, the Hippocratic Oath, and the Freedom of Therapy – The Legal Aspect of Phage Therapy". Her presentation will focus on balancing regulatory frameworks with the urgent need for accessible, life-saving treatments.

Phage therapy faces significant regulatory and ethical challenges, and Brenner will address several critical points:

- Regulatory Frameworks and Human Rights: Brenner will provide an overview of EU and German legal and regulatory frameworks, highlighting the tension between the right to safe drugs and the right to life-saving treatment in emergencies, especially concerning antimicrobial-resistant (AMR) infections and non-GMP phages.

- Ethical and Legal Questions: The session will explore whether it is ethical to deny life-saving treatments for safety reasons and whether regulatory bodies like the FDA and EMA can be held liable for prohibiting non-GMP phages if GMP phages are unavailable or unaffordable. Additionally, Brenner will discuss the validity of scientific evidence derived from anecdotal sources versus the necessity of randomized controlled trials (RCTs) and whether these trials need to be redesigned. The legal status of phage therapy as "experimental" and the potential liability of clinicians who refuse phage therapy when it could save a patient will also be examined.

- Combatting Antimicrobial Resistance (AMR): The presentation will include the One Health approach, integrating human, animal, and environmental health practices. Brenner will highlight Georgia's successful model, advocating for the promotion of phages as primary interventions, reserving chemical antibiotics for situations where phages are ineffective.

 

Speakers Lineup

  • Robert T. Schooley, University of California, San Diego, USA

Clinical Trials in Phage Therapeutics: Looking Under the Hood

  • Ekaterina Chernevskaya, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Russia

Adaptive Phage Therapy in the Intensive Care Unit: From Science to Patients

  • Jean-Paul Pirnay, Queen Astrid Military Hospital, Belgium

Magistral Phage Preparations: Is This the Model for Everyone?

  • Barbara Brenner, Kanzlei BRENNER, Germany

Regulatory restrictions vs. Human Rights, the Hippocratic oath and the Freedom of therapy– The legal aspect of phage therapy

  • Nannan Wu, Shanghai Public Health Clinical Center, Fudan University, China

Phage Therapy: A Glimpse into Clinical Studies Involving Over 150 Cases

  • Graham F. Hatfull, University of Pittsburgh, USA

Mycobacteriophages and Their Therapeutic Potential

  • Antonia P. Sagona, University of Warwick, United Kingdom

Genetic Engineering of Phages to Target Intracellular Bloodstream E.coli Infections

  • Paul Turner, Yale University, USA

Leveraging Evolutionary Trade-Offs in Development of Phage Therapy

  • Pieter-Jan Ceyssens, Sciensano, Belgium

Quality control of phage Active Pharmaceutical Ingredients (APIs) in Belgium

  • Wolfgang Weninger, Medical University of Vienna, Austria

The Phageome in Normal and Inflamed Human Skin

  • Sabrina Green, KU Leuven, Belgium

Making Antibiotics Great Again: Phage resistance in vivo correlates to resensitivity to antibiotics in pan-resistant Pseudomonas aeruginosa

  • Rodrigo Ibarra Chávez, University of Copenhagen, Denmark

Phage Satellites, a Diversity of Extradimensional Symbionts and Pathways to Phage Therapy

  • Domenico Frezza, University of Roma Tor Vergata, Italy

Towards efficient phage therapies: investigation of phage / bacteria equilibrium with metagenome of dark matter in natural samples

  • Besarion Lasareishvili, Eliava Institute of Bacteriophage, Microbiology and Virology, Georgia

Modern Concepts of Phage Therapy: An Immunologist’s Vision

  • Kilian Vogele, Invitris, Germany

Cell-Free Production of Personalized Therapeutic Phages Targeting Multidrug-Resistant Bacteria

  • Frederic Bertels, Max Planck Institute for Evolutionary Biology, Germany

Improving Phages through Experimental Evolution

  • Eugene V Koonin, National Institutes of Health, USA

Evolution and megataxonomy of viruses: the place of phages in the virosphere

  • Federica Briani, University of Milan, Italy

Addressing Phage Resistance to Enhance the Robustness of Phage Therapy for Pseudomonas aeruginosa Infections in People with Cystic Fibrosis

  • Jumpei Fujiki, University of California San Diego, USA

Phage therapy: Targeting intestinal bacterial microbiota for the treatment of liver disease

 

Targeting Phage Therapy 2024 Supporters: Cellexus, Precision Phage, Jafral.

Contributing Partner: PHAGE Therapy, Applications, and Research Journal.

Media Partner: Bacteriophage.news.

For more information, registration details, list of attendees and the program, please visit: www.phagetherapy-site.com.


SEE

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