Thursday, May 01, 2025

INDIA

Exposure to extreme heat and cold temperature is leading to additional preventable deaths, new 19-year study suggests




There’s no time to be lost to reduce deaths from heatwaves and extreme cold in India, where study took place



 News Release 

Taylor & Francis Group





Urgent action must be taken to reduce the ever-rising number of people killed by extreme temperatures in India, say the authors of a new 19-year study which found that 20,000 people died from heatstroke in the last two decades.  Cold exposure claimed another 15,000 lives. 

 

Findings published today in the peer-reviewed journal Temperature, also revealed that deaths from heatstroke are more common in men of working age and identified the states that are hotspots for deaths from heatstroke and from hypothermia and other conditions fuelled by the cold. 

 

There is an upward moving, increasing trend in terms of mortality due to heatstroke and exposure to cold in India, with glaring variation across states.  

 

“Deaths due to heatstroke is more significant, compared to deaths due to cold exposure, albeit recording an upward trend,” says the study’s lead author Professor Pradeep Guin, whose research at the O.P Jindal Global University (JGU), in Sonipat, India, is at the intersection of climate change, environment, health, politics and governance. 

 

Hundreds of people die from the heat or cold each year in India and many of these deaths are avoidable. 

 

Last year, Mungeshpur, in Delhi, recorded highest-ever summer temperature in India, at 52.9°C (126.1°F). Every summer, in India, we hear about heat-related deaths, which is avoidable. Similarly, some parts of the country – not the traditionally colder states – report deaths due to cold waves, which can be controlled. However, there needs to be adequate infrastructural and social safety-net support, the authors state.  

 

“With an intense heatwave forecast to hit most of the country this summer and extreme weather events becoming more frequent around the globe as the world warms, there is no time to be lost in raising awareness about the dangers of extreme temperatures and putting in place measures to reduce their impact. 

 

“Support systems exist, but more needs to be done,” Professor Guin adds. 

 

There is growing recognition of the harm excessive temperatures can do to health, however previous research has focused on developed nations and one-off events, such as heatwaves, rather than looking at low and middle-income countries and extreme temperatures that are starting to recur year after year. 

 

India’s size and geography make it prone to extremes of heat and cold and, when designing measures to keep the population safe, it is important to know which people and places are most at risk. 

 

To identify the people who are most vulnerable to extremes of temperature and the states with the highest death tolls, Professor Guin and a group of scholars from JGU, conducted country-level analysis assessing 19 years (2001–2019) of data, and state-level analysis with 14 years (2001–2014) data.  
 
The separate period of analysis was due to “variability in availability of data”. They sourced most of their data from official data sources, such as the India Meteorological Department (IMD), the National Crime Records Bureau (NCRB), the Reserve Bank of India (RBI), and the Office of the Registrar General and Census Commissioner. 

 

Analysis of temperature data from the Indian Meteorological Department and records of deaths from natural causes showed in India, between 2001 and 2019, there were a minimum of: 

 

  • 19,693 deaths from heatstroke  

  • 15,197 deaths from cold exposure  

 

Not all deaths are typically recorded and so the figures may be an underestimate. 

 

Nationally, maximum number of deaths due to both heatstroke and exposure to cold was reported in 2015 alone as: 

  • 1,907 deaths due to heatstroke  

  • 1,147 due to cold exposure.  

Contrary to global evidence, which have found that women tend to be more susceptible to extreme heat, more males in India died due to exposure to extreme temperatures.  
During the study period (2001–2019), male deaths compared to female were three to five times higher due to heatstroke, and four to seven times more due to exposure to cold.  

People in the age-group of 45-60 were most susceptible to die both due to heatstroke and cold exposure, followed by the elderly (60 and above) and those in between 30-45 years.  

“The higher death toll from heatstroke in working-age men may reflect the fact that men are more likely to work outdoors than women,” explains Professor Guin, who is also an expert in public policy. 

 

“Even with improvements in the female labour force participation rate in India in the recent years, there are more men working outside in the open environment to meet their household needs. Physically demanding outdoor work, such as construction work, should be halted during heatwaves and those with other outdoor jobs, such as auto rickshaw drivers and gig economy workers, should be provided with adequate relief measures such as shaded parking areas with provisions for drinking water and toilets. Essentially, those who are working outside are more exposed to extreme heat, thereby the more vulnerable gender to death,” said Professor Guin.  

 

“We believe that the Government should consider offering some form of social support to outdoor workers, particularly low-income workers and those on a daily wage, who may feel they have no option but to turn up to work, whatever the temperature.” 

 

 

As to why more people died from the cold, despite winters getting warmer, this could be because the change in temperature wasn’t uniform across the country. 

 

“While the average winter temperature is increasing, some parts of India are experiencing new lows,” says Professor Guin. “These states are not used to cold temperatures and so likely don’t have measures in place to deal with them, which could explain why the number of deaths from the cold is rising.” 

 

A separate analysis of state-level data from 2001–2014, indicates that the three most vulnerable states to extreme heat are Andhra Pradesh, Uttar Pradesh, and Punjab. 

 

Andhra Pradesh, on the east coast of Southern India, had the highest death toll from heatstroke followed by Uttar Pradesh and Punjab, in the north of the country. 
 
Uttar Pradesh, Punjab, and Bihar are the top three states in terms of cold exposure mortality.  

 

By conducting this more detailed state-level analysis – which including monitoring other factors, apart from extreme temperature exposure, to explain mortality – the research team was able to demonstrate in large urban populations, where more is spent on health, and other social sectors, there were fewer extreme temperature-related deaths. 

 

Professor Guin adds: “Should it be surprising that most deaths due extreme temperatures are not being reported from traditionally either the hottest or coldest regions in India? This is likely due to higher adaptative mechanisms that help residents survive the harshest of temperature. On the other hand, states which recorded more extreme temperature-related deaths are likely to have lower adaptive mechanisms and need greater infrastructural and social safety-net support.” 

 

Co-author, Professor Nandita Bhan, of the Jindal School of Public Health and Human Development at the JGU, say the results show that there is an urgent need to develop and strengthen action plans for individual states. 

 

“Several states in India are developing heat action plans that can provide relief through innovative built environment initiatives, and these need study as well as scale-up, including expanding cold action plans across more vulnerable states.” 

 

Local and simple language should be used to raise awareness about the danger posed by extreme temperatures. The number and quality of night shelters should be increased and living conditions for homeless people improved.  Other measures include providing more shade, by for example, covering bus stops and walkways. The health system must also be better prepared and early warning systems need to be improved. 

 

“In the future, further research and analytics at sub-national levels, including districts will be able to guide district authorities to make localised intervention plans, including improved early warning systems and enhanced welfare programs,” says fellow co-author Keshav Sethi, a doctoral candidate at the Jindal School of Government and Public Policy. 

 

“Collecting and collating data on temperature and mortality for a country the size and scale of India is challenging, and initiatives of state agencies to maintain these data archives is commendable. It allowed researchers like us to test our hypotheses and can lead to evidence-informed policy,” concludes Professor Bhan.  

 

“We are hopeful that our work will lead to a further momentum of collaborations to understand the global and national impacts of climate change on human health.” 

 

The study’s limitations mainly relate to data.  The analysis did not include socioeconomic data or information from hospital records and the state-level data only covered 2001 to 2014. 

 

$2.7 million NIH grant to fund first comprehensive syphilis test



Penn State





UNIVERSITY PARK, Pa. — In the United States, syphilis cases rose by nearly 80% between 2018 and 2023, with 209,253 cases reported in the latest year of data. The infection, which can be transmitted sexually or passed from mother to infant during birth, is curable but only if diagnosed quickly. Left untreated, syphilis can progress from painless lesions to brain and cardiovascular damage. Despite the first recorded outbreak of syphilis occurring more than 500 years ago — with some researchers theorizing that it has plagued humans for thousands of years — there still isn’t a way to quickly and reliably test for active syphilis infection, according to Penn State Professor Dipanjan Pan.

Now, with a four-year, $2.7 million grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases, Pan is setting out to change that. In collaboration with his clinical partners at Penn State Health, Carle Foundation Hospital and University of Alabama Birmingham, Pan aims to develop a one-step confirmatory laboratory test that can definitively diagnose active syphilis infection within 10 minutes.

“The ‘great imitator’ is back! Syphilis is known to mimic symptoms of many other sexually transmitted and infectious diseases, making it difficult to diagnose and treat,” said Pan, the Dorothy Foehr Huck & J. Lloyd Chair Professor in Nanomedicine at Penn State. “Syphilis cases in the United State are increasing at an alarming rate, and the need for a rapid diagnostic test that can quickly inform treatment and management decisions is desperately needed. An accurate diagnosis of syphilis relies on recognizing a constellation of symptoms, reviewing medical and sexual history, and performing multiple laboratory tests.”

When infected, the body makes antibodies to combat the bacterium Treponema pallidum, which causes syphilis. This happens whether a person is symptomatic or not. These antibodies — known as treponemal-specific antibodies — persist in a person for decades, even if the infection never becomes active or after successful treatment of an active infection, so they are not a good indicator of an active infection. The body can also make non-treponemal antibodies in response to active infection, but the reaction is not limited to syphilis, so clinicians must test for both types of antibodies to make a more definitive diagnosis and decide on a treatment plan.

“There are only two syphilis rapid tests approved by the U.S. Food and Drug Administration, but they detect only treponemal-specific antibodies, which could be from a decades-old infection that was already successfully treated,” said Pan, who is also a professor of materials science and engineering and of nuclear engineering.

He explained that definitively diagnosing active syphilis, and deciding on a course of treatment, requires testing for the non-specific non-treponemal antibodies that indicate active infection, preferably with a semi-quantitative result. That means the number of antibodies in the blood sample are counted, a process that takes two to seven days and specialized instruments, so the tests are typically outsourced to a lab instead of the doctor’s office.

“This is necessary to determine appropriate treatment with high sensitivity and low false-positive rates,” said Pan, who is also a member of the Center for Infectious Disease Dynamics in the Huck Institutes for the Life Sciences at Penn State. “Combining treponemal and non-treponemal assays within the same platform will provide a more definitive, stand-alone diagnosis of syphilis.”

The proposed platform makes use of highly sensitive electrochemical sensors to detect changes in current resulting from the direct interaction of both antibody types with biological material released from the bacterium and damaged host cells and the bacterium itself. The sensors — made from graphene, an atomically thin material that is incredibly sensitive to such changes — are capable of both detecting and quantify various proteins or molecules associated with these changes.

In preliminary tests using commercially available blood serum samples, Pan said, the researchers found that the sensors could detect both kinds of antibodies in less than 10 minutes with high sensitivity. This initial work — funded by the Centers for Disease Control and Prevention — was conducted by Pan, Parikshit Moitra, previously a research assistant professor in Pan’s lab and now an assistant professor at the Indian Institute of Science Education and Research in Berhampur, India, and with Ketan Dighe, a graduate student in biomedical engineering at Penn State.

“This is the first study using electrochemical sensor for an integrated assay — or comprehensive test to detect multiple targets — for highly sensitive, rapid, point-of-care detection of both treponemal and non-treponemal antibodies needed to accurately diagnose active syphilis infection,” Pan said. “Our goal is to simultaneously detect and quantify these antibodies, identifying and differentiating active from past cases of syphilis within 10 minutes to fulfill an urgent, unmet global need.”

Upon completing testing and refinement of their platform, Pan said the team plans to build a blood sample extraction device integrated with a simple reader — much like an at-home glucose meter — to produce results in 10 minutes. The study team is actively looking for commercial partners to further develop the platform.

The collaborating investigators include Casey Pinto, a nurse practitioner at Penn State Health and an assistant professor in the Department of Public Health Sciences in the Division of Epidemiology at the Penn State College of Medicine; Carla Rafferty, a family medicine physician at Carle Foundation Hospital; Tor Jensen, managing director of the Biomedical Research Center at Carle Foundation Hospital; and Barbara Van Der Pol, a professor of medicine and public health at the University of Alabama at Birmingham (UAB) and the director of the UAB Infectious Diseases STD Laboratory.

 

US Study marks rise in psychotherapy outpatient visits and declines in medication use for mental health care



Columbia University's Mailman School of Public Health





Psychotherapy assumed a larger role in outpatient mental health care while psychiatric medication without psychotherapy became less common, according to a new study at Columbia University Mailman School of Public Health and Columbia University Irving Medical Center. The findings are published in the American Journal of Psychiatry.

 “After years of American mental health care moving towards greater use of psychiatric medications, the pendulum has started swinging back towards psychotherapy,”  said Mark Olfson, MD, MPH, Columbia Mailman School professor of Epidemiology and Psychiatry.

Among adults receiving outpatient mental health care between 2018 and 2021, an increase occurred in use of only psychotherapy, from 11.5 percent in 2018 to 15.4 percent in 2021, respectively; while taking medication only declined from 68 percent to 62 percent. Increases also occurred in psychotherapy visits and total national psychotherapy expenditures ($31 billion to $51 billion) with a decrease in patients

receiving psychotherapy from psychiatrists from 41 percent to 34 percent. Psychiatric medications included antidepressants – the most common class of medications -- antipsychotics, stimulants or other ADHD medications, anxiolytics or hypnotics, and mood stabilizers obtained from pharmacies during the survey year.

Much of the change occurred between 2018 and 2019, which indicates that factors other than the COVID pandemic and the rise of telemental health care contributed to the shift in outpatient mental health treatment, according to Olfson. During the study period, a significant increase in the average number of visits occurred for patients with mild or moderate distress but not for patients with serious disturbances.

To investigate recent national trends in outpatient mental health care, the researchers analyzed data from four representative surveys of the U.S. household population, the 2018–2021 Medical Expenditure Panel Survey, focusing on adults with outpatient mental health visits (17,821)

including psychotherapy visits (6,415).  They further presented data trends on mental health patients receiving psychotherapy only, those receiving medications, or a combination of the two. 

“Psychiatrists provided psychotherapy to a decreasing percentage of all psychotherapy patients, which may have increased the need for psychiatrists to refer patients to and collaborate with non-physician psychotherapists,” observed Olfson. “At the same time, social workers and counselors, but not psychologists, assumed a larger role in providing psychotherapy and there was an increase in the average number psychotherapy visits per patient. A decrease in the fraction of patients with just one or two psychotherapy visits further suggests there was a decline in early drop out.  Americans are becoming more willing to seek out and stick with psychotherapy.” 

According to Olfson, psychotherapy by mental health counselors may increase further following a recent change in Medicare reimbursement policy that allows mental health counselors and licensed marital and family therapists to bill for psychotherapy.

Co-authors are Chandler McClellan and Samuel H. Zuvekas, Agency for Healthcare Research and Quality; Melanie Wall, Columbia Mailman School of Public Health and Columbia University Irving Medical Center; and Carlos Blanco, National Institute on Drug Abuse.

Columbia University Mailman School of Public Health

Founded in 1922, the Columbia University Mailman School of Public Health pursues an agenda of research, education, and service to address the critical and complex public health issues affecting New Yorkers, the nation and the world. The Columbia Mailman School is the third largest recipient of NIH grants among schools of public health. Its nearly 300 multi-disciplinary faculty members work in more than 100 countries around the world, addressing such issues as preventing infectious and chronic diseases, environmental health, maternal and child health, health policy, climate change and health, and public health preparedness. It is a leader in public health education with more than 1,300 graduate students from 55 nations pursuing a variety of master’s and doctoral degree programs. The Columbia Mailman School is also home to numerous world-renowned research centers, including ICAP and the Center for Infection and Immunity. For more information, please visit www.mailman.columbia.edu.

 U$A

New research analysis predicts that reductions in Medicaid access could result in poorer health outcomes, including increased deaths



Eliminating the ACA provision expanding Medicaid access could also drive millions to delay needed care, says a new research letter in the Lancet by investigators at the Keck School of Medicine of USC, Boston University and the University of Amsterdam



Keck School of Medicine of USC





A new analysis provides evidence that reductions in access to Medicaid could increase deaths and cause financial hardship to people currently covered under an expansion of Medicaid that was implemented under the Affordable Care Act (ACA).

Medicaid is a joint federal and state program that provides health insurance to qualifying individuals who are unable to obtain it through their employer, private insurance companies, or Medicare, the public insurance program for seniors and people with disabilities. About two in five births in the United States are financed by Medicaid, and although it’s not widely known, most people covered by the program have jobs. Funded jointly by the federal government and individual states and administered by state agencies, Medicaid goes by different names in some places, such as Medi-Cal in California or MassHealth in Massachusetts.

Investigators at the Keck School of Medicine of USC, Boston University and the University of Amsterdam in the Netherlands built upon existing research to predict the impacts of potentially reducing the scope of coverage of Medicaid. In a peer-reviewed research letter published in The Lancet, the authors found that reductions in Medicaid coverage or access could lead to thousands of additional deaths among working-age Americans, disastrous financial burden for hundreds of thousands, and delays in necessary care for millions.

“More than 70 million people depend on Medicaid for everything that has to do with their health, whether it’s for preventive care, accidents or surgeries,” said co-senior author Brian P. Lee, MD, an associate professor of clinical medicine at the Keck School of Medicine. “The devastating effects of losing coverage are not just limited to the patient. Cuts have a ripple effect on patients’ children, their mothers and fathers, and seniors who depend on them for care. Because health care systems are reliant on Medicaid, cuts can even affect a community at large.”

The ACA originally mandated that Medicaid cover more people, but a Supreme Court ruling made the expansion voluntary. Today, 40 states and the District of Columbia have taken part. A body of research has shown that expansion to be a boon to public health, including a 2022 study led by Lee concluding that the expansion was associated with a reduction in deaths — an effect that was stronger in places where more previously uninsured people gained coverage.

The current Lancet article extrapolates from that study and a few others to show the flip side of the coin: What could happen if 15.5 million fewer Americans were covered by Medicaid?

Based on the reductions in mortality resulting from the expansion of Medicaid found in the 2022 study, the scientists determined that additional deaths among those aged 25 to 64 years old could reach 14,660 within a single year among – a number that ranks as the equivalent of the seventh leading cause of death in that age group across states which expanded coverage. Low-income rural populations could be disproportionately affected.

The researchers also examined catastrophic health care expenditures — a term defined by economists as out-of-pocket costs exceeding 30% of household income. The team estimated that more than 600,000 additional Americans between ages 25 and 64 could face this type of serious financial burden.

“We have to ask ourselves, how can anyone have the opportunity to succeed if they’re that deep in debt?” Lee said. “How can they be expected to contribute to society?”

Lack of insurance coverage can also pressure people to ignore some health problems rather than incur the costs required to address them. The research letter’s authors found that reversing the Medicaid expansion could lead up to 8.7 million people to avoid needed medical care. Putting off care for health issues when they are most easily treated can lead to worse outcomes and higher costs down the line.

“Time and time again, research has shown that preventative care and health coverage are actually cost saving,” Lee said. “The true, long-term effects of these decisions might be much larger than we expect and play out on a 10- to 20-year horizon.”

Reducing coverage could also touch the lives of people not currently enrolled in Medicaid. The investigators noted that funds from the program are so important to hospitals in underserved rural areas that cuts could result in closures, potentially leaving entire communities without reliable access to care.

The research letter’s first and corresponding author is Brooke Nichols of Boston University and Amsterdam University. Jennifer Dodge, a USC associate professor of research medicine and population and public health sciences, is a co-author, and Nahid Bhadelia and Jacob Bor, both of Boston University, are co-senior authors.

New global index defines what makes digital economies resilient and inclusive



Digital Evolution Index from The Fletcher School at Tufts University provide in-depth look at technology adoption and the state of AI around the world



Tufts University

New Global Index Defines What Makes Digital Economies Resilient and Inclusive 

image: 

Digital Evolution Index from The Fletcher School at Tufts University Provides In-Depth Look at Technology adoption and the state of AI around the world.

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Credit: Digital Planet




Digital Planet, published by The Fletcher School at Tufts University has unveiled the Digital Evolution Index, charting the progress of 125 economies around the world have made in advancing their digital economies, developing artificial intelligence (AI), and integrating connectivity into the lives of billions.

This latest edition of the index, developed in collaboration with Mastercard, illustrates global digital development, provides insights into the key factors driving change and momentum, and explores the implications for economies grappling with the aftermath of a global pandemic, while contemplating a future shaped by AI.

The emerging post-pandemic landscape of the digital planet is not characterized by rapid digital transformation but rather by slowing growth. This global digital deceleration is particularly noteworthy in measures of demand and institutions. Gender and class digital inclusion metrics, in particular, appear to be plateauing. Since 2019, institutions' ability to regulate technological innovation, foster trust, and achieve bureaucratic efficiency has stagnated.

Notably, AI is creating an amplification effect, accelerating existing digital advantages and reinforcing the dominance of digitally advanced economies. This suggests a potential "winner-takes-most, if not all," scenario in the relationship between AI and digital development. As AI increasingly drives innovation and competitiveness, countries that fall behind in AI investment and adoption may find it increasingly challenging to close the gap.

Other key findings include:

Progress to Digital Parity: Digital inclusion has slowed globally, with Europe and Central Asia leading in gender digital inclusion, while Africa and the Middle East lag despite making strides. Low-income countries face challenges due to economic and social factors, with the rural-urban digital divide remaining especially persistent across most regions.

The Resilience of Digital Entrepôts: Small nations serving as digital hubs have demonstrated remarkable resilience during and after the pandemic by emphasizing agility, openness, and support for innovation. These digital entrepôts now serve as potential models for cross-border cooperation in the AI era.

China's Mobile-First Ascension: China has become the first primarily mobile-driven economy to reach the Stand Out Zone, despite having lower PC/laptop ownership compared to its peers. Its success with mobile super apps across various income groups presents an aspirational model for other mobile-first developing nations such as India, Indonesia, and Vietnam.

Three-Speed Digital Transformation: Europe's digital landscape has evolved into three distinct clusters (Established, Surging, and Emerging economies), creating an interdependent ecosystem despite varying development rates. This three-speed model offers diverse pathways to digital advancement and creates natural policy laboratories, with Europe's digital future reliant on effective cross-cluster collaboration.

“The Digital Evolution Index reveals a crucial inflection point in the global digital landscape. As digital technologies account for an increasingly significant portion of the overall economy, the post-pandemic digital deceleration we are witnessing isn't merely a temporary slowdown but signals the beginning of a fundamental restructuring of digital economies worldwide,” said Bhaskar Chakravorti, Chair of Digital Planet and Dean of Global Business at The Fletcher School. “As AI amplifies existing advantages and creates what could become a 'winner-take-most' scenario, we are seeing new challenges emerge in the form of potential tariffs and growing policy debates around taxing digital services. This comes at a critical time when the digital component of economies is expanding rapidly. Leaders must navigate these complex trade tensions while ensuring their increasingly digital-dependent economies can harness AI's transformative potential. The diverse models we are observing across regions offer valuable lessons in building resilient digital economies amid these evolving global pressures.”

A Global Outlook on Digital Evolution

Digital Evolution captures an economy’s historical momentum from the physical past to the digital present.

Mapping over 92% of the world’s population and drawing on 15 years of data, Digital Evolution measures 184 indicators in 125 economies across four key pillars: institutional environment, demand conditions, supply conditions, and the capacity for innovation and change. These are segmented into four categories:

  • Stand Out economies—the United States, Singapore, Hong Kong, South Korea, Ireland, Estonia, UAE, Israel, Czechia, Malaysia, Lithuania, Latvia, Poland, China, Italy, Saudi Arabia, and Qatar—are both highly digitally advanced and exhibit high momentum. They are leaders in driving innovation, building on their existing advantages efficiently and effectively.
  • Stall Out economies—such as Sweden, the United Kingdom, the Netherlands, Japan, and Canada—are mature digital economies with high levels of digital adoption despite slowing digital momentum. They typically drive economic sustainability by investing in digital inclusion and strong institutions.
  • Break Out economies—such as India, Indonesia, Thailand, Armenia, and Vietnam— are evolving rapidly. With significant headroom for growth, these economies are often highly attractive to investors.
  • Watch Out economies—such as Nigeria, South Africa, Colombia, Pakistan, and Sri Lanka—have several infrastructural and institutional gaps. Despite this, young people are showing enthusiasm for a digital future with increased use of mobile devices.

The link to the full report and methodology can be found here.

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About the Digital Evolution Index

The Digital Evolution Index, researched and authored by The Fletcher School faculty and students with the support of Mastercard, provides world-leading, state-of-play reporting on the progress that countries have made in advancing their digital economies.

About Digital Planet

Digital Planet, an interdisciplinary research initiative of The Fletcher School’s Institute for Business in the Global Context, is dedicated to understanding the impact of digital innovations on the world and providing actionable insights for policymakers, businesses, investors, and innovators.