Thursday, September 04, 2025

 

Former Macalester College animal lab workers, alumni, and mental health experts raise alarm regarding student stress and coercion in deadly animal experiments




Physicians Committee for Responsible Medicine






ST. PAUL, Minn. — Former Macalester College animal laboratory workers joined distinguished alumni and more than 130 mental health professionals and animal welfare experts to call on Macalester President Suzanne Rivera, PhD, and other college leaders to protect students from psychological harm and end fatal animal experiments in psychology courses. Their letter, sent Sept. 4 as Macalester students begin classes, cites a new national survey that finds serious student intimidation with regard to participation in animal laboratories, as well as the risk of long-term harm to students working in the laboratory.

The OpinionWorks survey found that 83% of U.S. college students believe that animals should not be used in classroom teaching laboratories if the animals are killed afterward and if other methods can teach the same material without using animals. Yet 44% feel coerced into participating in the deadly experiments: 20% stated they would participate anyway to avoid problems, and another 24% stated that they would be nervous asking for the alternative activity. Two former Macalester laboratory workers complained about the treatment of animals and recurrent trauma from their jobs.

“The animal laboratory exercises put students in an impossible position,” write alumni Susan and James Graham, class of ’65 and recipients of the College’s Charles J. Turck Global Citizen Award for beneficial work; veterinarian Ingrid Taylor, class of ’95; and Clark Gustafson, class of ’75, and Jessica Wilson, class of ’21, both of whom were employed in the psychology department animal facility while students at Macalester. “Many have reservations about participating in animal experiments, particularly those that end fatally. Despite their reservations, however, students uniformly fear academic consequences for declining to participate. Understandably, they are often reticent about expressing ethical concerns.”

In psychology courses at Macalester, live animals are deprived of water for prolonged periods, then placed in “Skinner boxes,” where they have to work for water. Some experiments involve injecting animals with drugs and placing them in mazes. All are killed at the conclusion of the experiments. The psychology department has killed thousands of animals for more than 50 years.

Gustafson and Wilson, who worked in Macalester’s animal lab, say, “We were concerned by the treatment of the animals when we worked there and reported our concerns to our supervisors. Years later, we remain troubled by our experience and by the College’s failure to end its inappropriate use of animals.”

Harvard, Yale, Stanford, Princeton, Duke, the University of Michigan, the University of Pennsylvania, Carleton College, and most other schools replaced these animal exercises many years ago. The letter references several alternatives to animals that are readily available to use in psychology courses.

lawsuit filed June 3 against Macalester, brought by alumnus Neal Barnard, MD, president of the Physicians Committee for Responsible Medicine, calls on the college to stop needlessly killing animals in psychology classes’ “show and tell” exercises, citing the college’s posted ethics commitment.

“The vast majority of college students don’t want to participate in deadly animal experiments but are fearful of the consequences of not taking part,” says Dr. Barnard. “Colleges with old-fashioned animal labs put students in an awful position that many interpret as a choice between killing or flunking. Even if the laboratory is supposedly “optional,” students are afraid to say no.”

Macalester’s website says that its “animal welfare standards and ethical principles are applied at the highest possible level in any animal use or research conducted at or in association with the college” and that it follows the federal Animal Welfare Act, which incorporates ethical principles called the Three Rs—for the replacement, reduction, and refinement of animal use in research.

In its motion to dismiss, which Dr. Barnard responded to in court papers, Macalester backed away from its own ethics statements, calling them mere “generic phrases”—known legally as “puffery.” The college wrote, “These statements are, at most, ‘vague or highly subjective’ statements of superiority—not representations of material fact,” drawing comparisons with statements used to sell dog food or breakfast cereal.

“Given that animals’ lives are at stake, Macalester’s brazen statement that it did not really mean its ethics policy is an affront to science, students, donors, the faculty, and the public,” Dr. Barnard said.

The lawsuit seeks, among other actions, an order compelling Macalester “to cease its use of animal laboratories in psychology instruction and in all other areas for which nonanimal methods are available.”

Founded in 1985, the Physicians Committee for Responsible Medicine is a nonprofit organization that promotes preventive medicine, conducts clinical research, and encourages higher standards for ethics and effectiveness in education and research.

 

Penn research identifies best ways to debunk COVID vaccine misinformation



Researchers tested types of messages that debunked vaccine misinformation with people considering getting vaccinated or boosted.




University of Pennsylvania School of Medicine





People hesitant about getting a COVID vaccine were more likely to consider getting the shot after hearing a myth explained and corrected with facts, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Science has continually proven the safety and efficacy of COVID vaccines, including the mRNA technology behind their development. However, vaccine hesitancy remains common.

“Vaccines are only effective if people take them,” said lead author Jessica Fishman, PhD, director of the Message Effects Lab at the University of Pennsylvania. “Part of ensuring broader distribution of vaccines is having a proven way to deliver factual information about them.”

How to debunk myths

There are three commonly used strategies to debunk false information, no matter the subject:

  • Telling people an untruth followed by a fact.
  • Telling people a fact, then a lie, then another fact. (The “fact sandwich” method.)
  • Just presenting the fact.

The first strategy has earned a bad reputation, and some experts have advised against its use.

“There have been concerns that the first method could ‘backfire’ by repeating the myth and making it more salient and possibly more believable,” said Fishman, who is also an assistant professor in Psychiatry and a director of behavioral vaccination research at the Penn Institute for RNA Innovation. In fact, according to the research, none of the debunking strategies reduced people’s intention to get the vaccine booster, and the first approach strengthened their intentions to get the shot, as published in Vaccine.

Study methods

In a randomized study of 890 U.S. adults with vaccination safety concerns were exposed to one of the three types of myth-busting strategies and then completed a questionnaire to gauge their intent to receive the vaccine or booster. Their strength of intention was compared to intentions in a control group.

For example, debunking a common argument around the vaccines’ supposed impact on fertility looked like this:

 

Experimental arm 1:
 
Traditional 

Myth-followed-by-fact

Experimental arm 2:  
 
“Fact sandwich” of 

fact/myth/fact 
Experimental arm 3:  
 
Fact only  
MYTH: The COVID-19  vaccine causes infertility. 

FACT: There is no evidence showing that COVID-19 vaccines cause fertility problems in women or men. In fact, because the COVID-19 vaccine doesn't cause infertility, it is recommended for people who are pregnant, trying to get pregnant now, or might become pregnant in the future, as well as their partners. 

 

 

FACT: There is no evidence showing that COVID-19 vaccines cause fertility problems in women or men. 

MYTH: The COVID-19 vaccine causes infertility.

FACT: Because the COVID-19 vaccine doesn't cause infertility, it is recommended for people who are pregnant, trying to get pregnant now, or might become pregnant in the future, as well as their partners.

FACT: There is no evidence showing that COVID-19 vaccines cause fertility problems in women or men. In fact, because the COVID-19 vaccine doesn't cause infertility, it is recommended for people who are pregnant, trying to get pregnant now, or might become pregnant in the future, as well as their partners.

Because the team found that participants developed stronger intentions to get an updated shot after they were exposed to the “myth-followed-by-fact" message structure.  the research team believes that the debunking strategy may have earned an unnecessarily poor reputation.

Testing messages on a global scale

The Message Effects Lab was created during the pandemic by John L. Jackson, Jr, now University of Pennsylvania Provost. In the years since, Fishman has built on that foundation, collaborating with groups like the World Health Organization (WHO), as well as the Vaccine Education Center at Children’s Hospital of Philadelphia.

For example, Fishman explained that the WHO is seeking to debunk vaccination misinformation. At the WHO, some have asked if it is dangerous to repeat vaccination myths when trying to correct them with accurate information. Fortunately, the study Fishman led in partnership with the organization did not support this fear: all the commonly used debunking strategies may be safe.

The Message Effects Lab has also helped to evaluate the efficacy of other public health tools.

For example, during the pandemic, there were widespread concerns that employee COVID-19 vaccination mandates would ‘backfire’ by making the public more resistant to vaccination. In collaboration with Dolores Albarricin, PhD, an Amy Gutmann Penn Integrates Knowledge University Professor at the Annenberg School, they found the opposite to be true: Mandates strengthened vaccination intentions.

The Message Effects Lab is also focused on identifying the best ways to articulate the safety and efficacy of RNA technology.

“The work that [the] Message Effects Lab has been doing will only become more critical as technology increases, as artificial intelligence advances, and as our media environment continues to partition us into discrete audiences,” Jackson said. “Figuring out how to get accurate and actionable information to people inundated with competing and sometimes irreconcilable claims about the world remains incredibly important.”

 

UMD developing AI-powered warning system to predict disease tied to extreme weather



Project supported by $1.9 million multinational grant from funders including NSF




University of Maryland

Amir Sapkota 

image: 

Dr. Amir Sapkota, professor and chair of the Department of Epidemiology and Biostatistics at the UMD School of Public Health, whose team has developed the international partnership over the past several years. 

view more 

Credit: UMD





COLLEGE PARK, Md. — The University of Maryland will lead an eight-country research consortium to develop an artificial intelligence-powered early warning system to help communities prepare for and respond to diarrheal disease risks – and potentially other conditions – worsened by extreme weather events.

Americans and people around the globe are grappling with increasing incidence of extreme weather, from flooding to droughts. Now, funded by a three-year, $1.9 million joint grant, the Awareness Against Health Threats of Extreme Weather Events (AWARE) project will unite University of Maryland researchers with partners from Nepal, India, Vietnam, Indonesia, Taiwan, the United Kingdom and South Africa.

The international consortium is led by Dr. Amir Sapkota, professor and chair of the Department of Epidemiology and Biostatistics at the UMD School of Public Health, whose team has developed the international partnership over the past several years. Sapkota’s previous research piloted the study team’s approach, using AI to predict diarrheal outbreaks.

“Scientific data suggest extreme weather events will continue to increase in the near future, despite current mitigation efforts,” Sapkota said. “As such, there is an urgent need to use science and technology to develop tools that will help communities anticipate, prepare for and respond to the health threats posed by these extreme events.”

Other UMD colleagues, including Dr. Ronald Yaros (Philip Merrill College of Journalism), Drs. Huang Lin and Pin Wang (School of Public Health) and Hao He (College of Computer, Mathematical, and Natural Sciences) will collaborate with international partners to design and refine a mobile app for the early warning system. By integrating weather, health and demographic data, the system will provide timely, actionable information to public health agencies, non-governmental organizations (NGOs) and local leaders.

“This project will translate complex scientific data into practical tools that communities can use to save lives,” said Yaros, an associate professor at UMD. “By working across disciplines and borders, we can ensure the results reach the people who need it most.”

The AWARE project aims to strengthen community resilience in regions most affected by extreme weather events, reducing disease burdens and preventing health crises before they occur. Though the project will begin with a focus on predicting and preventing diarrheal disease, the team hopes to extend the focus to other climate-sensitive diseases including dengue later on.

AWARE is funded by a joint grant from the U.S. National Science Foundation and Future Earth (U.S.), United Kingdom Research and Innovation, National Research Foundation (South Africa), the National Science and Technology Council (Chinese Taipei) and the Belmont Forum Collaborative Research Action.

 

Ancient flower-visiting bug in amber



It seems that in the past, bugs also played an important role in plant pollination.



Eötvös Loránd University

Ancient flower-visiting bug in amber 

image: 

Figures:
A: Inclusion of Shaykayatcoris michalskii in 99-million-year-old burmite
B: Reconstructed outline of the insect
C: Artistic reconstruction of the new species (illustration by Márton Zsoldos)

view more 

Credit: Eötvös Loránd University





When we think of pollinating insects, bees, butterflies, or flies usually come to mind — but rarely true bugs. Yet it seems that in the past, they also played an important role in plant pollination. A Hungarian research group has now confirmed, based on an ancient bug preserved in nearly 100-million-year-old Burmese amber, that this behavior may have been more widespread among bugs in earlier stages of Earth’s history.

The study of amber inclusions is an important tool for uncovering the biodiversity and evolutionary patterns of past ages. Fossils of certain groups of organisms (for example, arthropods) are often poorly preserved and lack detail, surviving in good condition only when trapped in fossilized resin.

One of the most important amber deposits from the Mesozoic era is Burmese amber (also known as burmite). This amber formed during the Late Cretaceous, about 99 million years ago, on the West Burma terrane — a landmass that had already separated from the supercontinent Gondwana more than 100 million years earlier and remained in the equatorial region of the Tethys Ocean until the Late Eocene. As a result, although its wildlife originated from Gondwana, it evolved in isolation for millions of years, giving rise to a rich array of unique flora and fauna.

While studying such an inclusion, Péter Kóbor (Plant Protection Institute, HUN-REN ATK) and Márton Szabó (Department of Paleontology and Geology, Hungarian Natural History Museum, and Department of Paleontology, Eötvös Loránd University) discovered a flat bug (family Aradidae) belonging to the subfamily Prosympiestinae, which retains ancient (plesiomorphic) traits. This is the first known representative of this subfamily in Burmese amber.

The find is interesting even within the family, since all flat bugs previously known from Burmese amber belonged to more derived (apomorphic) groups, while older lineages were absent from the faunal inventory. What truly makes the newly described species, named Shaykayatcoris michalskii, remarkable, however, is its iridescent, shimmering exoskeleton — never before seen in this family.

Although iridescence is not uncommon among bugs, it is particularly unusual in such cryptic groups as flat bugs. True to their name, these insects typically live under tree bark and feed on fungal hyphae. Their lifestyle is associated with specific morphological adaptations, such as a strongly flattened body (dorsoventrally) and elongated stylets, which are coiled inside the head capsule at rest. By contrast, members of the Prosympiestinae subfamily differ both in lifestyle and morphology: their bodies are more cylindrical, and they live mostly in leaf litter or under logs and branches lying on the ground.

Iridescence may serve two functions. It can act as a deterrent (aposematism) if the coloration is bright (e.g., red) and highly conspicuous, but this is unlikely here since the bug’s base color is brownish. More probably, it functioned as camouflage, helping the insect blend into a floral environment — this explanation is more plausible.

The amber also contained plant fragments and a large amount of pollen surrounding the insect, with grains even stuck to its body. This, together with its iridescent coloration, suggests that the bug visited flowers — and likely played a role in pollination.

The discovery confirms that bugs’ role in flower visitation, and possibly in pollination, may have been much more significant in earlier evolutionary stages than it is today. Most modern bugs are no longer flower visitors, likely having been displaced from this “niche” by more specialized pollinators such as bees.

This finding helps us understand how today’s insect fauna evolved, and how species responded to competition and environmental changes. Armed with this knowledge, we can also better navigate current ecological and agricultural challenges — such as the decline of pollinators.

 

The study was published in Scientific Reports 

 

Wired for voices: Conserved brain responses in mammals




The ability to detect vocal sounds, and the more specialized skill of recognizing calls from one’s own species, is supported by evolutionarily ancient brain mechanisms, according to a new study from the ELTE Department of Ethology, Hungary.




Eötvös Loránd University

Dog and pig 

image: 

Comparative EEG reveals general and conspecific vocalization sensitivities in evolutionarily distant mammal species

view more 

Credit: Eötvös Loránd University




The ability to detect vocal sounds, and the more specialized skill of recognizing calls from one’s own species, is supported by evolutionarily ancient brain mechanisms, according to a new study from the ELTE Department of Ethology, Hungary. In the first-ever direct comparison of companion dogs, companion pigs, and humans, researchers from the university’s Neuroethology of Communication Lab examined the neural correlates of voice processing across these three distantly related mammals.   

For social species, distinguishing vocalizations from other sounds (e.g., machine sounds or water dropping) and recognizing when a voice belongs to a member of the same species can be crucial for survival and reproduction. “Although vocal sounds carry important information for many animals, it was previously unclear how these abilities are reflected in the brain across evolutionarily distant mammal species,” says Boglárka Morvai, postdoctoral researcher at the Neuroethology of Communication Lab and first author of the study.

Human participants, family dogs, and family pigs all took part in the same auditory experiment, listening to a variety of sounds including human, dog, and pig vocalizations (e.g., human sighs or coughs, dog barking, pig grunts), as well as non-vocal environmental noises. EEG electrodes, placed gently on the head, recorded the brain’s rapid electrical responses. The animals, relaxed and at ease with their human companions, participated without training or sedation.

„The results revealed a two-step pattern in the brain’s response. In humans and pigs, vocalizations of any kind triggered distinct brain activity almost immediately, within 200 ms after stimulus presentation, suggesting that such sounds stand out as especially salient. Recognition of a voice belonging to one’s own species appeared later, only after 300 ms in all three species, reflecting a more complex process of categorizing the vocalization. Remarkably, these patterns were very similar despite the large evolutionary distance between the three species, pointing to shared neural mechanisms that likely predates the divergence of their lineages some 90 million years ago.”

“Surprisingly, even though the tested dogs and pigs live closely alongside people, their brains didn’t show a special sensitivity for human voices,” notes Lilla Magyari, an earlier member of the lab, now associate professor at University of Stavanger, Norway, who co-supervised the study. “This supports the idea that these abilities were not affected by recent domestication, but are part of an ancient mammalian heritage.”

The findings not only shed light on the deep evolutionary roots of voice perception, but also highlight the value of studying companion animals to better understand the human brain. As Attila Andics, the PI of the lab explains, “Our results show that by working with animals who trust us enough to take part in these experiments, we can uncover fundamental biological mechanisms that have shaped communication for millions of years.”

The ability to detect vocal sounds, and the more specialized skill of recognizing calls from one’s own species, is supported by evolutionarily ancient brain mechanisms, according to a new study from the ELTE Department of Ethology, Hungary. In the first-ever direct comparison of companion dogs, companion pigs, and humans, researchers from the university’s Neuroethology of Communication Lab examined the neural correlates of voice processing across these three distantly related mammals. 

The ability to detect vocal sounds, and the more specialized skill of recognizing calls from one’s own species, is supported by evolutionarily ancient brain mechanisms, according to a new study from the ELTE Department of Ethology, Hungary. In the first-ever direct comparison of companion dogs, companion pigs, and humans, researchers from the university’s Neuroethology of Communication Lab examined the neural correlates of voice processing across these three distantly related mammals. 


Credit

Elodie Ferrando / Eötvös Loránd University