Tuesday, September 30, 2025

Childhood overeating can be a harbinger of later mental health struggles in girls, study finds


Researchers who followed more than 2,000 Quebec children from early childhood to adolescence did not find any similar link for boys



McGill University






Girls who overeat regularly in the preschool years are more likely to experience anxiety, impulsivity and hyperactivity in adolescence, according to a new study led by researchers at McGill University and the Douglas Research Centre.

The study followed more than 2,000 Quebec children using provincial data, tracking eating patterns reported by caregivers in early childhood and assessing mental-health symptoms when participants turned 15. The link between overeating and later difficulties was seen in girls, but not in boys.

Takeaway for caregivers

The findings suggest that children’s eating patterns can be early signals of mental-health challenges. The researchers emphasize, however, that the results show only associations, not that certain eating patterns necessarily cause later mental health challenges.

“Occasional overeating is normal, but if a child frequently overeats, it can be a sign of emotional struggles,” said senior author Linda Booij, Professor in McGill’s Department of Psychiatry and clinician-scientist at the Douglas Eating Disorders Continuum and Research Centre.

“The answer isn’t restriction. In fact, strict control can make things worse and even increase the risk of disordered eating,” she said. “Instead, parents and caregivers should also pay attention to children’s emotional well-being.”

Why girls and not boys?

The differing results for girls and boys may be partly explained by sociocultural factors, Booij said.

“It could be that parents may sometimes monitor girls’ eating more closely than boys’, and restrictive environments could be linked to increased risk of disordered eating later in life. The social context around girls’ eating habits may partly explain why overeating is linked with later difficulties for them,” she said.

The researchers identified three patterns of overeating in young children: about 60 per cent showed no signs of overeating, roughly 14 per cent began overeating early between ages two and four, and about 26 per cent started later, around age four.

Girls who started to overeat either early or later on were more likely than were the non-overeaters to report such symptoms as anxiety, hyperactivity and impulsivity at age 15.

Picky eating

Looking at picky eating told a different story. About one-third of the children were picky eaters in early childhood, and those habits tended to stay the same during their childhood. But unlike overeating, picky eating showed no connection to mental-health struggles in adolescence.

While many parents worry about picky eating, Booij says it is often a common developmental phase that, on its own, does not necessarily signal later emotional or behavioural problems. However, if picky eating persists over time or begins to interfere with a child’s growth, nutrition, emotional or daily functioning, it may be a sign of a more serious concern.

About the study

Trajectories of childhood eating behaviors and their association with internalizing and externalizing symptoms in adolescence” by Rachel Dufour (Concordia University) and Linda Booij et al., was published in BMC Pediatrics.

The study was supported by the Institut de la statistique du Québec, the Quebec ministries of health, education and family affairs, the Lucie and André Chagnon Foundation, the Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST), the Fonds de Recherche du Québec – Santé and Société et Culture, the Social Sciences and Humanities Research Council of Canada, the Canadian Institutes of Health Research and the Sainte-Justine Hospital research centre.

 

Cornell launches initiative to unravel the science of menopause




Cornell University






ITHACA, N.Y. -- Two centuries ago, few women lived long enough to reach menopause. Today, it marks a major inflection point in women’s health, yet remains poorly understood. Cornell researchers aim to change that.

Drawing on cutting-edge technology and interdisciplinary expertise, researchers are launching Menopause Health Engineering, a new initiative uniting faculty from Cornell’s Ithaca campus and Weill Cornell Medicine, to uncover how menopause shapes health and disease, and to develop urgently needed treatment strategies. The inaugural team includes nine faculty across four departments, with a core in the Meinig School of Biomedical Engineering.

Nozomi Nishimura, founder of the initiative and associate professor in the Meinig School, said gaining a better scientific understanding of menopause is important because it not only affects half of the population, but because its different phases and outcomes, when taken together, affect women for the majority of their lives.

“All kinds of conditions develop as women undergo this transition to menopause,” said Nishimura, “including cardiovascular disease, cancer, osteoporosis, dementia and metabolic diseases.”

Claudia Fishbach-Teschl, the James M. and Marsh McCormick Family Director of the Meinig School and collaborator on the initiative, noted that while many of these conditions are traditionally labeled as aging-related diseases, deeper, sex-specific factors are at play.

“These so-called aging diseases are affecting women very differently than men,” said Fischbach-Teschl, who is also the Stanley Bryer 1946 Professor of Biomedical Engineering, “yet we understand very little about how women are affected in this stage of their life.” 

One major contributor to that knowledge gap is a long-standing bias toward using male subjects in biomedical research and clinical trials. For example, using male animals for obesity research is faster, as male mice gain weight more quickly. Also, male animals are often cheaper than females, which has led to gaps in understanding of female biology, aging and disease, said Nishimura, who studies Alzheimer's disease and cardiovascular disease.

“It never really occurred to me – and this was a hole in my education – that when we’re talking about diseases of aging, we should really be looking at and considering something like menopause,” Nishimura said.

Osteoporosis, for example, is tied not only to bone health, but muscle and metabolic health. It also plays a significant role in breast cancer risk and progression. Understanding intertwined problems like menopause and multi-organ diseases requires the kind of interdisciplinary approach found at Cornell, according to Nishimura.

“At Cornell we have really strong researchers for diseases of aging,” Nishimura said. “We have a powerful engineering and tool-building culture that sets us at an advantage. In terms of researching women’s health and menopause, we have an opportunity.”

Menopause is more than a biological transition – it’s a technological challenge. Only about 2% of health sector private investment is directed toward women-specific health needs. But new research initiatives such as Menopause Health Engineering could catalyze significant advances in biomedical technology and clinical care.

“You need technology in order to understand, diagnose and treat changes that are imposed by menopause,” said Fischbach-Teschl, adding that examples include imaging to observe cells in real time, biomedical devices to measure different physiological signals, and body-on-a-chip systems that can mimic how cells behave in a human’s body.

“There is also a need for advanced computation, because with a large dataset, you need to figure out how to use the data to inform therapies or other experiments. Finally, there is usually some sort of innovation and technology needed to translate your findings into changes in clinical care or therapy.”

Beyond the lab and clinic, Menopause Health Engineering is equally committed to student engagement. Researchers plan to integrate their research with student experiences, embedding menopause and women’s health questions into senior design projects and clinical immersion terms at Weill Cornell Medicine.

To sustain the initiative’s momentum, faculty are actively pursuing funding opportunities to support the group’s collaborative research efforts. At the same time, smaller, innovative initiatives – such as joint fellowships that pair trainees from different labs – will help grow the initiative from the ground up. 

“Faculty are already meeting regularly to discuss findings, build collaborations and shape the future of menopause research,” Nishimura said. Their goal is not only to fill critical scientific gaps, but to redefine how women’s health is understood, prioritized, taught and advanced for generations to come.”

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Home-delivered nutrition services for older adults under the Older Americans Act



JAMA Network Open



About The Study:

 The findings of this qualitative study of home-delivered nutrition services for older adults suggest that home-delivered meals programs achieved their intended outcomes and yielded meaningful benefits beyond their stated purpose that remain to be quantified. The findings also support funding the Older Americans Act Nutrition Program.



Corresponding author: To contact the corresponding author, Kali S. Thomas, Ph.D., email kali.thomas@jhu.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ 

(doi: 10.1001/jamanetworkopen.2025.34747)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

Study explores use of religion and spirituality to help patients cope with stress of radiation therapy for gynecologic cancers



Researchers identify the most meaningful questions to help clinicians open conversations about spirituality with patients




The Mount Sinai Hospital / Mount Sinai School of Medicine





New York, NY (September 30, 2025) – Researchers at the Mount Sinai Health System have identified specific ways in which addressing religion and spirituality during radiation therapy can play an important role in the care of patients with gynecologic cancers. The study, published in the September/October 2025 issue of Practical Radiation Oncology, is the first to identify which aspects of spiritual history patients themselves prioritize and find most meaningful.

A collaborative team from Mount Sinai and NYU Langone Health led the research. Key contributors included Lauren Jacobs, MD, a resident physician in Radiation Oncology at the Icahn School of Medicine at Mount Sinai; Karyn Goodman, MD, MS, Vice Chair for Research and Quality in the Department of Radiation Oncology at Mount Sinai; and senior author Stella Lymberis MD, Director of Quality Initiatives and GYN Disease Management Group Co-Lead in the Department of Radiation Oncology at NYU Langone. This is the first study to assess which spiritual history questions matter most to patients.

Using the validated FICA Spiritual History Tool (developed in 1999 by Christina Puchalski, MD, and a group of primary care physicians); the team interviewed 11 patients with gynecologic malignancies who had received external beam radiation therapy and/or brachytherapy. These patients adhered to a range of faiths, including Christianity, Buddhism, Judaism, Islam, and Hinduism.

“Our study highlights that patients want these conversations and that spirituality plays a vital role in how they cope with stress during cancer treatment,” said Dr. Jacobs, first author. “By asking the right questions, clinicians can create meaningful dialogue without adding burden to already time-limited visits.”

The study found that 82 percent of patients rated their faith as extremely important, giving it the highest score possible. On average, participants considered nearly all of the FICA Spiritual History Tool questions to be helpful, with six questions consistently identified as especially valuable. The two questions most often highlighted as meaningful ways to begin conversations with providers were: “Do you have spiritual beliefs that help you cope with stress?” and “Have your beliefs influenced you in how you handle stress?”

The findings are especially significant for patients undergoing gynecologic radiation therapy, such as brachytherapy, which can be invasive and emotionally distressing. Previous research has shown that nearly one-third of patients with cervical cancer develop acute stress symptoms after treatment, with more than 40 percent reporting post-traumatic stress months later.

“Patients are telling us clearly that their spiritual health matters just as much as their physical health,” said Dr. Goodman. “By engaging with them on these issues, we can better support emotional well-being, reduce distress, and provide truly whole-patient cancer care.”

The research team plans to expand the study to larger patient cohorts, apply the approach earlier in the cancer journey (diagnosis and pre-treatment), and extend it to other cancer types. They also aim to develop protocols and training for clinicians and trainees to normalize and integrate these discussions into routine practice.

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About the Icahn School of Medicine at Mount Sinai

The Icahn School of Medicine at Mount Sinai is internationally renowned for its outstanding research, educational, and clinical care programs. It is the sole academic partner for the seven member hospitals* of the Mount Sinai Health System, one of the largest academic health systems in the United States, providing care to New York City’s large and diverse patient population. 

The Icahn School of Medicine at Mount Sinai offers highly competitive MD, PhD, MD-PhD, and master’s degree programs, with enrollment of more than 1,200 students. It has the largest graduate medical education program in the country, with more than 2,600 clinical residents and fellows training throughout the Health System. Its Graduate School of Biomedical Sciences offers 13 degree-granting programs, conducts innovative basic and translational research, and trains more than 560 postdoctoral research fellows.

Ranked 11th nationwide in National Institutes of Health (NIH) funding, the Icahn School of Medicine at Mount Sinai is among the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges.  More than 4,500 scientists, educators, and clinicians work within and across dozens of academic departments and multidisciplinary institutes with an emphasis on translational research and therapeutics. Through Mount Sinai Innovation Partners (MSIP), the Health System facilitates the real-world application and commercialization of medical breakthroughs made at Mount Sinai.

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* Mount Sinai Health System member hospitals: The Mount Sinai Hospital; Mount Sinai Brooklyn; Mount Sinai Morningside; Mount Sinai Queens; Mount Sinai South Nassau; Mount Sinai West; and New York Eye and Ear Infirmary of Mount Sinai.