Sunday, January 11, 2026

 

New report highlights the potential for artificial intelligence to accelerate the real-world impact of research




Taylor & Francis Group





new report by HEPI and Taylor & Francis explores the potential of AI to advance translational research and accelerate the journey from scientific discovery to real-world application.

Using Artificial Intelligence (AI) to Advance Translational Research (HEPI Policy Note 67), authored by Rose Stephenson, Director of Policy and Strategy at HEPI, and Lan Murdock, Senior Corporate Communications Manager at Taylor & Francis, draws on discussions at a roundtable of higher education leaders, researchers, AI innovators and funders, as well as a range of research case studies, to evaluate the future role of AI in translational research.

Key findings
The report finds that AI has the potential to strengthen the UK’s translational research system, but that realising these benefits will require careful implementation, appropriate governance and sustained investment.

Key findings include:

  • AI could accelerate translational research by enabling faster analysis of large and complex datasets, supporting knowledge synthesis and improving links between disciplines. However, the availability and quality of such datasets remain uneven, limiting the ability of AI tools to support research translation in some fields.
  • Access to AI skills and expertise is increasingly important and building this access into interdisciplinary frameworks will be a key component of driving translational research.
  • AI can improve the accessibility and visibility of research, including through plain-language summaries, semantic search (search functions that utilise concepts and ideas and not simply keywords, giving a more accurate result) and new formats aimed at audiences beyond academia.
  • There are clear risks associated with AI use, including challenges around reproducibility, bias, deskilling, academic integrity, intellectual property and accountability.

Recommendations
To ensure AI supports high-quality and responsible translational research, the report makes recommendations for research funders, institutions and publishers, including:

  • Setting clear expectations for the responsible use of AI, including alignment with guidance such as the UK Research Integrity Office’s Embracing AI with Integrity.
  • Investing in trustworthy and ethical AI, including work to improve transparency, reduce bias and support reproducibility.
  • Strengthening support for interdisciplinary research, including better recognition of team-based work and clearer routes to access AI expertise.
  • Supporting shared and open AI research infrastructure to reduce duplication and make researcher-developed tools more widely available.
  • Encouraging data sharing and reuse, alongside investment in infrastructure that supports secure and responsible access to data.

Rose Stephenson, Director of Policy and Strategy at HEPI and co-author of the report, said: “The UK has extraordinary research strengths, but too many ideas struggle to make the journey from discovery to real-world use. AI has the potential to support this process by speeding up analysis, connecting disciplines and improving access to research. However, these benefits will only be realised if AI is used transparently, ethically and in ways that strengthen, rather than replace, human expertise.”

Rebecca Lawrence, VP Knowledge Translation at Taylor & Francis, said: “We are grateful to all the roundtable participants and those who shared case study insights. The valuable discussions and the ensuing process of putting the policy note together has highlighted the benefits of working collectively to harness the power and opportunity that responsible AI use can provide for translational research.”

By investing in interdisciplinary expertise, ethical governance and infrastructure, stakeholders can help transform translational research, enabling more of the latest research to deliver meaningful societal benefits.

Read the full report: Using Artificial Intelligence to Advance Translational Research


Using the physics of radio waves to empower smarter edge devices



Duke engineers publish new method to use analog radio waves to boost energy-efficient edge AI


Duke University






As drones survey forests, robots navigate warehouses and sensors monitor city streets, more of the world’s decision-making is occurring autonomously on the edge—on the small devices that gather information at the ends of much larger networks.

But making that shift to edge computing is harder than it seems. Although artificial intelligence (AI) models continue to grow larger and smarter, the hardware inside these devices remains tiny.

Engineers typically have two options, neither ideal. Storing an entire AI model on the device requires significant memory, data movement and computing power that drains batteries. Offloading the model to the cloud avoids those hardware constraints, but the back-and-forth introduces lag, burns energy and presents security risks.

Researchers at Duke University are exploring a third option, called WIreless Smart Edge networks (WISE), that bypasses the limitations of both approaches. They’ve shown that large AI model weights can be smartly embedded in the form of radio waves delivered over the air between devices and nearby base stations, opening a path to energy-efficient edge AI without the usual cost in energy, speed or size.

This work, published online in Science Advances on January 9, is led by Tingjun Chen, the Nortel Networks Assistant Professor of Electrical and Computer Engineering, alongside Dirk Englund’s team at the MIT Research Laboratory of Electronics (RLE). This work was supported by the NSF Athena AI Institute, with subsequent continuation and expansion also supported by the Army Research Office.

At the heart of the approach is a concept called in-physics analog computing.

Traditional digital computing occurs through binary code. Devices convert data into ones and zeros, move those bits into a digital processor and compute long sequences of math operations. Even a simple task like unlocking a phone with biometrics triggers a rapid sequence of calculations. It’s reliable but not efficient for small, battery-powered devices.

In-physics computing works differently. Instead of shuttling ones and zeros from an edge device to a distant processor, the natural behavior of radio waves completes part of the math along the way.

In WISE, a base station stores the full AI model and broadcasts a radio frequency (RF) signal that encodes the model’s weight values—numbers required to complete those calculations. When the signal reaches a nearby device, radio hardware in the device mixes the broadcast signal with its own input data that can naturally perform computing directly in the RF or analog domain. One example is a passive frequency mixer that “approximates” the multiplication of two time-domain RF signals. That analog in-physics mixing process—directly taking place at RF—performs a key step in most deep learning models without the need of a digital processor.

“We’re taking advantage of computations that common, miniaturized electronics already gives us,” Chen said. “Instead of running every step of the model on a chip designed for digital computing, the radio waves themselves help carry information in a way optimized for the computation.”

Because the device doesn’t store the entire model or run it digitally, it overcomes the big memory and energy costs that limit edge AI today.

Zhihui Gao, a PhD student in Chen’s lab and lead author on the paper, said the idea could benefit many kinds of devices. Drones, cameras and traffic sensors all generate data continuously, yet they struggle to run the advanced models that would help interpret those data.

“Technology is moving toward smaller devices that can do more than ever before,” Gao said. “In order to achieve that, we need new improvements in edge computing. With WISE, we have shown how devices can run on powerful AI without relying on heavy chips or distant servers.”

Gao noted another advantage of WISE is its ability to use existing infrastructure. Base stations already set up for 5G, emerging 6G or WiFi routers could be augmented to broadcast these AI models with relatively small adjustments. Plus, everyday wireless devices already contain the hardware, such as frequency mixers, needed to perform the in-physics computation.

“We’re not adding exotic components or creating entirely new hardware,” Gao said. “We’re reusing features that are widely deployed and don’t consume extra energy.”

In experiments, WISE achieved nearly 96 percent image classification accuracy while consuming more than an order of magnitude less energy than leading digital processors.

Although promising, WISE is still in its beginning stages. The current prototype works over short distances, but longer-range testing would require stronger transmission or integration with next-generation wireless gear. And while the approach is flexible, broadcasting multiple AI models simultaneously would require efficient multiplexing of the time-frequency-space resources or additional spectrum bandwidth.

Even so, the researchers see broad potential in applications. One base station could support a swarm of drones in a search and rescue mission or help traffic cameras coordinate intersection signals. 

“This is the next step in wireless technologies becoming as powerful as wired ones,” Chen said. “Beyond delivering data and information, these findings open a new direction, in which future networks may distribute intelligence by blending communication and computation to enable energy-efficient edge AI at massive scale.”

 

Danish chemist's invention could make counterfeiting a thing of the past


University of Copenhagen




Every year, companies lose billions of kroner when goods are copied or illegally resold. But a new digital and legally binding fingerprint developed at the University of Copenhagen makes products impossible to counterfeit. Royal Copenhagen is among the first brands in the world to use the solution.

In 2021, counterfeit goods worth 467 billion US dollars were traded globally. The most well-known counterfeits are luxury goods such as bags, watches and sunglasses. Today, almost all types of products are counterfeited – from cosmetics, toys, sports equipment and car parts to electronics and medicines.

Counterfeit goods not only mean huge financial losses and hundreds of thousands of lost jobs, they can also be directly dangerous to consumers. Counterfeit medicines and cosmetics can pose serious health risks, while fake electronics can suddenly catch fire. Yet the problem is growing year by year.

Thomas Just Sørensen, a chemist at the University of Copenhagen, has invented a unique solution to combat this problem. Together with Danish entrepreneurs and investors, he has developed the O−KEY® technology – a kind of digital fingerprint that makes any physical product impossible to counterfeit.

"Imagine throwing a handful of sand onto a glass plate. The grains of sand will land in a random pattern that is impossible to copy. We use exactly the same principle when we produce our artificial fingerprints," says Thomas Just Sørensen.

The fingerprint consists of a mark measuring one millimetre square, which is sprayed onto either the product itself or its packaging using transparent ink. The ink contains various microparticles that form a random pattern that could never be recreated. The mark is embedded in a tiny area, is scannable with a standard smartphone, and serves as legally recognised proof of authenticity.

“The marking gives companies an unprecedented opportunity to protect their products, enforce contracts and document authenticity down to the individual item level,” says Thomas Just Sørensen.

Unique identification of Royal Copenhagen products

The Danish porcelain company Royal Copenhagen is delighted with the new technology. The company is among the first brands in the world to use the labelling, and the results are already good in the initial implementation. Royal Copenhagen has initially used O-KEY® as a method to track the journey of their products to the end consumer.

"O−KEY® has set new standards for how we protect our brand. The implementation gave us immediate transparency across our distribution chain – and assurance that our products are protected with legally recognised proof. It is simple, effective and absolutely crucial," says Allan Schefte, SVP Continental Europe Fiskars Denmark A/S.

In addition to royal porcelain, O-KEY labels have also been used on Kay Bojesen figures and international security products, among other things.   

From university to business

The new technology is based on many years of research in materials chemistry at the University of Copenhagen. With support from the Innovation Fund and private investors, the research evolved into the company PUFIN-ID®, which today has 16 employees in Copenhagen.

Back in 2016, Thomas Just Sørensen overheard some colleagues talking about PUFs – physically unclonable functions – at a conference in northern France, and became interested in developing a fingerprint that is impossible to clone. Two years of research later, the professor published a scientific article in Science Advances about his groundbreaking technology, which the company O−KEY® is built around.

Since then, the company has grown steadily and has, among other things, built its own IT infrastructure, labelling machines and AI solution that keeps track of all the digital fingerprints that are made. 

"We have gone from having advanced science in a laboratory to having a mass-produced product and an app that you can download directly from the AppStore. Today, we see how O-KEY® technology can protect both Danish design classics and international luxury brands – while strengthening consumer confidence in security components and critical infrastructure. This shows how far university research can reach," says Thomas Just Sørensen.

Link to research articleshttps://sites.google.com/view/tjsgroup/publications

Blue book: Thomas Just Sørensen

Born: 1 June 1981, Aalborg

Position: Professor of Chemistry at the Department of Chemistry, University of Copenhagen

Education: BSc, MSc and PhD in Chemistry from the University of Copenhagen

Career: Postdoc at the University of Oxford and has worked at UCLA, Caltech, Geneva, since 2014 employed at the University of Copenhagen, where he is now a professor.

Research: Works with lanthanide chemistry, fluorescent dyes and optical sensors for anti-counterfeiting, among other things.

Entrepreneurship: Co-founder of the companies PUFIN-ID, FRS-Systems and KU-dyes.

Awards: Villum Young Investigator (2016), Lundbeckfondens Talentpris (2011) m.fl.


 

Hidden hotspots on “green” plastics: biodegradable and conventional plastics shape very different antibiotic resistance risks in river microbiomes




Biochar Editorial Office, Shenyang Agricultural University

Biodegradable and non-biodegradable plastics foster unique regimes of antibiotic resistance and virulence factors in aquatic plastispheres 

image: 

Biodegradable and non-biodegradable plastics foster unique regimes of antibiotic resistance and virulence factors in aquatic plastispheres

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Credit: Fengying Li, Hangru Shen, Ruirui Pang, Xueting Wang, Bing Xie, Min Zhan & Yinglong Su





Biodegradable plastics are not always safer for rivers and oceans, according to a new study that tracked how different plastics change the risk of antibiotic resistant bacteria over time in a real river.

A sharper look at “green” plastics

A team from East China Normal University placed common plastics in a tidal river in Shanghai for 88 days to see how they shaped microbial “cities” on their surfaces, known as the plastisphere. The researchers compared a biodegradable plastic, polylactic acid (PLA), with two widely used conventional plastics, polyvinyl chloride (PVC) and polystyrene (PS).​

“Our findings show that biodegradable plastics do not simply dissolve into the environment without consequence” says corresponding author Yinglong Su. “They create a different kind of risk that peaks during degradation and should not be ignored in environmental policy.”​

Plastics grow their own microbial worlds

When plastic floats in water it quickly becomes coated with a slimy biofilm of bacteria, viruses, and other microbes that is distinct from the surrounding water. This artificial habitat, called the plastisphere, can concentrate pathogens, antibiotic resistance genes and virulence factors that help microbes cause disease.​

In the Shanghai river experiment, all three plastics recruited unique microbial communities that looked very different from those in the river water itself. Some opportunistic pathogenic genera, including Vibrio and Acinetobacter, were consistently detected on plastic surfaces, raising public health concerns.​

Biodegradable versus conventional plastic risks

The study reveals that biodegradable and conventional plastics create fundamentally different risk patterns rather than a simple “high risk versus low risk” contrast.​

  • PVC acted as a long term hotspot for antibiotic resistance genes and mobile genetic elements which move DNA between microbes

  • PLA created a sharp but temporary spike in risk during its mid degradation stage

On PVC, multidrug resistance genes were enriched up to 3.5 times compared with river water and remained high across the 88 day experiment. PVC also carried the highest levels of mobile genetic elements such as transposases and integrases, which can accelerate the spread of resistance through horizontal gene transfer.​

PLA showed a different pattern. Early on its surface appeared less risky, but as the material began to break down the plastisphere shifted into a hotspot enriched in opportunistic pathogens like Vibrio and Acinetobacter along with a pronounced surge in multidrug and glycopeptide resistance genes. After this mid degradation peak, the risk declined as the PLA continued to fragment and its biofilm community changed again.​

High risk genomes on plastic surfaces

Using genome resolved metagenomics the team reconstructed 37 high quality microbial genomes to pinpoint which organisms were carrying both antibiotic resistance genes and virulence factors. This approach allowed the researchers to identify specific “high risk” strains that combine pathogenic traits with resistance and a high capacity for gene exchange.​

Some of the most concerning genomes were found on PVC and in river water where certain strains carried multiple resistance genes, dozens of virulence factors and large numbers of mobile genetic elements in the same genome. In PLA associated communities, one strain stood out as a potential “gene transfer vector” with very many mobile elements that could rapidly spread resistance once such genes are acquired.​

Rethinking plastic risk and policy

The authors argue that risk assessments for plastics must move beyond counting how long materials persist and instead consider the full life cycle of the plastisphere, from initial colonization through degradation. Conventional plastics like PVC pose a persistent, accumulating threat as long lived hubs for antibiotic resistance, while biodegradable PLA introduces a transient but intense risk window during breakdown when pathogenic and resistant microbes can flourish.​

“These results challenge the assumption that biodegradable plastics are automatically a safer choice in all contexts” says co first author Fengying Li. “Both biodegradable and conventional plastics can act as reservoirs and amplifiers of antibiotic resistance and potential pathogens, but they do so in very different ways.”​

The team suggests that future regulations and product design should consider how specific polymers shape microbial communities, resistance genes and virulence factors over time in real environments, not just how fast the material disappears. They also call for more monitoring of riverine plastispheres as critical interfaces between human activity, environmental pollution and the global spread of antibiotic resistance.​

 

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Journal reference: Li F, Shen H, Pang R, Wang X, Xie B, et al. 2026. Biodegradable and non-biodegradable plastics foster unique regimes of antibiotic resistance and virulence factors in aquatic plastispheres. Biocontaminant 2: e001  

https://www.maxapress.com/article/doi/10.48130/biocontam-0025-0026  

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About Biocontaminant:
Biocontaminant (e-ISSN: 3070-359X) is a multidisciplinary platform dedicated to advancing fundamental and applied research on biological contaminants across diverse environments and systems. The journal serves as an innovative, efficient, and professional forum for global researchers to disseminate findings in this rapidly evolving field.

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