Friday, February 28, 2025

 

Primary care practices with NPs are key to increasing health care access in less advantaged areas, Columbia Nursing study shows



Columbia University Irving Medical Center





NEW YORK, NY (February 28, 2025) -- Primary care practices that employ nurse practitioners (NPs) are more likely to serve socioeconomically disadvantaged communities than practices with no NPs on staff, Columbia University School of Nursing researchers report in JAMA Network Open. Assistant Professor Monica O’Reilly-Jacob, PhD, led the study, published online February 28, 2025.  

To better understand the distribution of NPs—who are increasingly critical to improving access to primary care—O’Reilly-Jacob and her colleagues looked at 79,743 primary care practices across the U.S., 53.4% of which employed NPs in 2023. The authors note that this is a big jump from 2012, when 21% of primary care practices employed NPs. 

Practices with NPs were more likely to be based in low-income (23.3% vs. 17.2%) and rural (11.9% vs. 5.5%) areas, the researchers found. Communities where primary care practices employed NPs had more people living below the poverty level (14.4% vs. 12.8%) and more people without high school diplomas (19.8% vs. 18.5%).  

“This study demonstrates that NPs are increasingly utilized for primary care delivery across the country, and especially within low-socioeconomic communities,” O’Reilly-Jacob and her colleagues note. “This is important as fewer medical residents are choosing to practice primary care, resulting in an estimated shortfall of 20,200-40,400 primary care physicians by 2036.” 

Policies are also needed to bring NPs to underserved areas, and retain them, the researchers add, “such as strengthening federal and state loan repayment programs, establishing pay parity in state Medicaid programs, and ensuring primary care provider designation for NPs across payers. Such steps would expand the capacity of the primary care system to better meet demand in communities where it is needed most.” 

The study was funded by the National Institute of Nursing Research. Columbia Nursing co-authors were Kyle Featherston, PhD, research program director, and Professor Lusine Poghosyan, PhD. 

About Columbia University School of Nursing    

Columbia University School of Nursing is advancing nursing education, research, and practice to advance health for all. As one of the top nursing schools in the country, we offer direct-entry master’s degrees, advanced nursing, and doctoral programs with the goal of shaping and setting standards for nursing everywhere. And, as a top recipient of NIH research funding, we address health disparities for under-resourced populations and advance equitable health policy and delivery.  

Through our expansive network of clinical collaborations in New York City and around the world —including our dedicated faculty practice, the ColumbiaDoctors Nurse Practitioner Group — we cultivate a culture of innovation and diversity and champion a community-centered approach to care. Across the Columbia Nursing community, we encourage active listening, big thinking, and bold action, so that, together, we’re moving health forward.  

Columbia University School of Nursing is part of Columbia University Irving Medical Center, which also includes the Columbia University Vagelos College of Physicians and Surgeons, the Mailman School of Public Health, and the College of Dental Medicine. 

 

New device could allow you to taste a cake in virtual reality



From fish soup to coffee, ‘e-Taste’ delivered, study finds



Ohio State University




COLUMBUS, Ohio – Novel technology intends to redefine the virtual reality experience by expanding to incorporate a new sensory connection: taste.  

The interface, dubbed ‘e-Taste’, uses a combination of sensors and wireless chemical dispensers to facilitate the remote perception of taste – what scientists call gustation. These sensors are attuned to recognize molecules like glucose and glutamate — chemicals that represent the five basic tastes of sweet, sour, salty, bitter, and umami. Once captured via an electrical signal, that data is wirelessly passed to a remote device for replication. 

Field testing done by researchers at The Ohio State University confirmed the device’s ability to digitally simulate a range of taste intensities, while still offering variety and safety for the user. 

“The chemical dimension in the current VR and AR realm is relatively underrepresented, especially when we talk about olfaction and gustation,” said Jinghua Li, co-author of the study and an assistant professor of materials science and engineering at Ohio State. “It’s a gap that needs to be filled and we’ve developed that with this next-generation system.”

The system, whose development was inspired by previous biosensor work of Li’s, utilizes an actuator with two parts: an interface to the mouth and a small electromagnetic pump. This pump connects to a liquid channel of chemicals that vibrates when an electric charge passes through it, pushing the solution through a special gel layer into the mouth of the subject. 

Depending on the length of time that the solution interacts with this gel layer, the intensity and strength of any given taste can easily be adjusted, said Li. 

“Based on the digital instruction, you can also choose to release one or several different tastes simultaneously so that they can form different sensations,” she said. 

The study was published today in the journal Science Advances.

Taste is a subjective sense that can change from one moment to another. Yet this complex feeling is the product of two of the body’s chemical sensing systems working in tandem to ensure what you eat is safe and nutritious, the gustation and the olfactory (or smell) senses. 

“Taste and smell are greatly related to human emotion and memory,“ said Li. “So our sensor has to learn to capture, control and store all that information.” 

Despite the difficulty involved in replicating similar taste sensations for a majority of people, researchers found that in human trials, participants could distinguish between different sour intensities in the liquids generated by the system with an accuracy rate of about 70%. 

Further tests assessing e-Taste’s ability to immerse players in a virtual food experience also analyzed its long-range capabilities, showing that remote tasting could be initiated in Ohio from as far away as California. Another experiment involved subjects trying to identify five food options they perceived, whether it was lemonade, cake, fried egg, fish soup or coffee. 

While these results open up opportunities to pioneer new VR experiences, this team’s findings are especially significant because they could potentially provide scientists with a more intimate understanding of how the brain processes sensory signals from the mouth, said Li. 

Plans to enhance the technology revolve around further miniaturizing the system and improving the system’s compatibility with different chemical compounds in food that produce taste sensations. Beyond helping to build a better and more dynamic gaming experience, the study notes that the work could be useful in promoting accessibility and inclusivity in virtual spaces for individuals with disabilities, like those with traumatic brain injuries or Long Covid, which brought gustatory loss to mainstream attention. 

“This will help people connect in virtual spaces in never-before-seen ways,” said Li. “This concept is here and it is a good first step to becoming a small part of the metaverse.”

Other Ohio State co-authors include Shulin Chen, Yizhen Jia, Tzu-Li Liu, Qi Wang and Prasad Nithianandam and Chunyu Yang, including Bowen Duan and Zhaoqian Xie from Dalian University of Technology, Xiao Xiao and Changsheng Wu from the National University of Singapore, Xi Tian from Tsinghua University. 

This work was supported by the National Science Foundation, the National Institute Of Biomedical Imaging and Bioengineering, the Chronic Brain Injury Pilot Award Program at Ohio State, the Center for Emergent Materials; the Center for Exploration of Novel Complex Materials, the Institute for Materials Research, the National Natural Science Foundation of China and the Dalian Outstanding Young Talents in Science and Technology. 

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Contact: Jinghua Li, Li. 1107@osu.edu

Written by Tatyana Woodall, Woodall.52@osu.edu

 

How do the universe’s highest-energy particles originate? Magnetic outflows stemming from star mergers, analysis concludes



New paper gives scientists a groundbreaking tool for understanding cataclysmic events


New York University





Ultrahigh Energy Cosmic Rays are the highest-energy particles in the universe, whose energies are more than a million times what can be achieved by humans. But while the existence of UHECRs has been known for 60 years, researchers have not succeeded in formulating a satisfactory explanation for their origin that explains all the observations.  

But a new theory introduced by New York University physicist Glennys Farrar provides a viable and testable explanation for how UHECRs are created.

“After six decades of effort, the origin of the mysterious highest-energy particles in the universe may finally have been identified,” says Farrar, a Collegiate Professor of Physics and Julius Silver, Rosalind S. Silver, and Enid Silver Winslow Professor at NYU. “This insight gives a new tool for understanding the most cataclysmic events of the universe: two neutron stars merging to form a black hole, which is the process responsible for the creation of many precious or exotic elements, including gold, platinum, uranium, iodine, and xenon.”

The work, which appears in the journal Physical Review Letters, proposes that UHECRs are accelerated in the turbulent magnetic outflows of Binary Neutron Star mergers—spewed out from the merger remnant, prior to formation of the final black hole. The process simultaneously generates powerful gravitational waves—some already detected by scientists at the LIGO-Virgo collaboration.  

Farrar’s Physical Review Letters proposal explains, for the first time, two of the most mysterious features of UHECRs: the tight correlation between a UHECR’s energy and its electric charge and the extraordinary energy of a handful of the very highest energy events.

Stemming from Farrar’s analysis are two consequences that can provide experimental validation in future work:

  • The very highest energy UHECRs originate as rare “r-process” elements, such as xenon and tellurium, motivating a search for such a component in the UHECR data. 
  • Extremely high-energy neutrinos, originating from UHECR collisions, are necessarily accompanied by the gravitational wave produced in the parent neutron star merger.  

The research was supported, in part, by grants from the National Science Foundation (PHY-2013199, PHY-2413153).

 

Rice researchers develop efficient lithium extraction method, setting stage for sustainable EV battery supply chains



Solid-state electrolyte membranes revolutionize lithium harvesting with near-perfect selectivity




Rice University

Menachem Elimelech 

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Menachem Elimelech, the Nancy and Clint Carlson Professor of Civil and Environmental Engineering (Photo credit: Gustavo Raskosky/Rice University).

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Credit: (Photo credit: Gustavo Raskosky/Rice University).




In the race to meet the growing global demand for lithium — a critical component in batteries for electric vehicles — a team of researchers from Rice University’s Elimelech lab has developed a breakthrough lithium extraction method that could reshape the industry.

In their study published in Science Advances, the researchers demonstrated near-perfect lithium selectivity by repurposing solid-state electrolytes (SSEs) as membrane materials for aqueous lithium extraction. While originally designed for the rapid conduction of lithium ions in solid-state batteries — where there are no other ions or liquid solvents — the highly ordered and confined structure of SSEs was found to enable unprecedented separation of both ions and water in aqueous mixtures.

This discovery presents a potential breakthrough in sustainable resource recovery, reducing reliance on traditional mining and extraction techniques that are both time-consuming and environmentally damaging.

“The challenge is not just about increasing lithium production but about doing so in a way that is both sustainable and economically viable,” said corresponding author Menachem Elimelech, the Nancy and Clint Carlson Professor of Civil and Environmental Engineering.

To make lithium extraction more environmentally sustainable, researchers have been exploring direct lithium extraction technologies that recover lithium from unconventional sources such as oil- and gas-produced water, industrial wastewater and geothermal brines. These methods, however, have struggled with ion selectivity, particularly when trying to separate lithium from other ions of similar size or charge like magnesium and sodium.

The novel approach developed by Elimelech and his team hinges on a fundamental difference between SSEs and conventional nanoporous membranes. Whereas traditional membranes rely on hydrated nanoscale pores to transport ions, SSEs shuttle lithium ions through an anhydrous hopping mechanism within a highly ordered crystalline lattice.

“This means that lithium ions can migrate through the membrane while other competing ions, and even water, are effectively blocked,” said first author Sohum Patel, who is now a postdoctoral researcher at the Massachusetts Institute of Technology. “The extreme selectivity offered by our SSE-based approach makes it a highly efficient method for lithium harvesting as energy is only expended towards moving the desired lithium ions across the membrane.”

The research team, which also includes Arpita Iddya, Weiyi Pan and Jianhao Qian — postdoctoral researchers in Elimelech’s lab at Rice — tested this phenomenon using an electrodialysis setup, where an applied electric field drove lithium ions across the membrane. The results were striking: Even at high concentrations of competing ions, the SSE consistently demonstrated near-perfect lithium selectivity with no detectable competing ions in the product stream — something conventional membrane technologies have been unable to achieve.

Using a combination of computational and experimental techniques, the team investigated why the SSEs exhibited such remarkable lithium-ion selectivity. The findings revealed that the rigid and tightly packed crystalline lattice of the SSE prevented water molecules and larger ions like sodium from passing through the membrane structure. Magnesium ions, which have a different charge than lithium ions, were also found to be incompatible with the crystal structure and were thus rejected.

“The lattice acts as a molecular sieve, allowing only lithium ions to pass through,” said Elimelech. “This combination of highly precise size and charge exclusion is what makes the SSE membrane so unique.”

The researchers noted that while competing ions did not penetrate the SSE, their presence in the feed solution reduced lithium flux by blocking available surface sites for ion exchange, a challenge they believe can be addressed through further material engineering.

With lithium shortages on the horizon, industries reliant on lithium-ion batteries, including automotive, electronics and renewable energy sectors, are searching for additional lithium sources and more sustainable extraction methods. SSE-based membranes could play a crucial role in securing a stable lithium supply without the environmental toll of traditional mining.

“By integrating SSEs into electrodialysis systems, we could enable direct lithium extraction from a range of aqueous sources, reducing the need for large evaporation ponds and chemical-intensive purification steps,” said Patel. “This could significantly lower the environmental footprint of lithium production while making the process more efficient.”

The findings also suggest broader applications beyond lithium for SSEs in ion-selective separations.

“The mechanisms of ion selectivity in SSEs could inspire the development of similar membranes for extracting other critical elements from water sources,” said Elimelech. “This could open the door to a new class of membrane materials for resource recovery.”

 

How many languages can you learn at the same time? – Ghanaian babies grow up speaking two to six languages





University of Potsdam





The study, which examined 121 babies aged three to twelve months in Accra, the capital of Ghana, demonstrates a remarkable variety of language input in the early months of life. The children are regularly exposed to two to six languages. Strikingly, the number of caregivers the children have also ranges between two and six, and babies who have more adults in their daily lives who regularly take care of them also hear more different languages. In Ghana, families often live in so-called “compound buildings”, where many everyday interactions take place in the courtyard, where family, neighbors and other relatives play an important role in the lives of children.

“The idea that a child learns only one particular language from a single caregiver, as is often assumed in Western cultures, does not apply to these communities. Rather, children are surrounded by a rich spectrum of linguistic inputs from the very beginning,” says Paul O. Omane, the first author of the study. “The majority of studies on children's language acquisition have been conducted in Western industrialized nations, which is why they often focus on a rather narrow conception of multilingualism. Our research shows that other societies show a much more vibrant multilingual environment,” the study's lead researcher, Prof. Dr. Natalie Boll-Avetisyan adds.

A key finding of the study is the distinction between direct and indirect language input. While English is primarily acquired through indirect channels such as television and official communication, children receive most of the local languages (such as Akan, Ga and Ewe) through direct contact with their caregivers. Accordingly, the proportion of direct input is higher in the local languages than in English, which is predominantly present as indirect input.

It is often emphasized how important direct language contact is for language acquisition,” Natalie Boll-Avetisyan says. ”However, our results suggest that indirect input – especially through media and official communication – also plays an essential role in the children’s daily lives, particularly in urban contexts.”

As a result of their empirical study, the researchers call for a broader view in language research. The common assumptions do not reflect the diversity and complexity found in other cultural contexts such as Ghana. The study makes it clear that it is not only the number of languages a child hears, but also the diversity of people and the different forms of input that have a decisive influence on language acquisition. “Our research shows that for many children, a multilingual environment is a dynamic, vibrant reality from the very beginning. Multilingualism is not just a bonus, but a fundamental part of children's identity and social structure,” the researcher says.

The study on the Internet:
Omane, P. O., Benders, T., & Boll-Avetisyan, N. (2025). Exploring the nature of multilingual input to infants in multiple caregiver families in an African city: The case of Accra (Ghana). Cognitive Development. In press. DOI: https://doi.org/10.1016/j.cogdev.2025.101558

 

Virginia Tech to lead $10 million critical mineral research coalition in Appalachia



Virginia Tech
Expand Appalachia team using downhole geophysics to detect the presence of rare earth elements. 

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Expand Appalachia team using downhole geophysics to detect the presence of rare earth elements.

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Credit: Photo by Richard Bishop for Virginia Tech.





Virginia Tech is spearheading a research coalition to reveal the untapped potential of the greater Appalachian Mountains region.

This coalition aims to accelerate the identification and characterization of unconventional critical mineral resources throughout the area. It brings together academic institutions, research laboratories, federal and state natural resource offices, and consultancies, all collaborating with the end goal of boosting regional economic growth and creating new jobs.

The research team, led by Richard Bishop, professor of practice in the Department of Mining and Minerals Engineering and researcher in the Virginia Center for Coal and Energy Research, will be funded through a $7.5 million grant from the U.S. Department of Energy. The project also includes more than $2 million in cost share from project partners and industry stakeholders, bringing the total project to nearly $10 million.

This initiative is part of the Department of Energy's Carbon Ore, Rare Earth, and Critical Minerals (CORE-CM) program, which seeks to establish regional coalitions focused on accelerating the development of critical mineral supply chains from unconventional resources.

Named Expand Appalachia CORE-CM, this project is part of a broader federal effort to reduce dependence on imported critical minerals and support the development of domestic supply chains. This initiative aims to help advance cost effective and environmentally responsible processes to produce and refine critical minerals and materials in the United States.

“We're identifying critical minerals that can be recovered from unconventional resources,” said Bishop. “By unconventional, we mean innovative sources that haven't been fully explored or considered before. These critical minerals are essential for alternative energy applications, such as solar panels and electric vehicles, as well as for components in modern electronics like smartphones, batteries, and semiconductors.”

The Expand Appalachia project builds on Bishop’s previous $2.71 million Department of Energy project, Evolve Central Appalachia. It aimed to develop strategies to enable the Central Appalachia coal basin to realize its full economic potential in producing rare earth elements, critical minerals, and high-value, nonfuel, carbon-based products. The study prioritized a geographic region that primarily included southern West Virginia, eastern Kentucky, eastern Tennessee, and southwest Virginia.

The Evolve Central Appalachia team collected and analyzed more than 700 geologic and mine waste samples to make an initial assessment of the regional potential for rare earth element and critical mineral production. Team members also prioritized stakeholder engagement, giving more than 50 outreach and educational presentations over a 2 1/2-year period.

The Expand Appalachia project follows a similar approach but will expand both the geographic scope and the type of resources under consideration. The new region of study spans 11 states throughout the greater Appalachian region from Tennessee to Maine. Working with project partners and industry collaborators, the team will collect and analyze various material and legacy mine waste samples to characterize mineral structure and concentration levels. Targets will include both coal and non-coal resources as well as power generation facilities and other unconventional critical mineral sources throughout the region.

The objectives of this project are to:

  • Identify the amount and location of critical mineral resources in the region
  • Develop strategies to use existing infrastructure, industries, and businesses to drive economic growth
  • Create and execute plans to educate and involve community stakeholders
  • Prepare and begin implementation of a workforce development plan to train future technicians, skilled workers, and STEM professionals
  • Develop plans to establish regional technology innovation centers

The research team will assess regional infrastructure, including abandoned mines throughout the region, and identify industries that could benefit from production. Many coal-producing communities in Appalachia have seen a downturn, but the grant from the Department of Energy could supply fresh jobs. The research team will develop strategies to boost economic growth, close supply chain gaps, attract investment, and enhance workforce education and training.

“The great thing is that we've united as a region, bringing together experts in critical mining and mineral processing from industry and various universities to tackle the challenge of sourcing in-demand minerals,” Bishop said. “The supply chain of these minerals is at risk, so we're assessing domestic sources to determine their locations and concentrations.”

The Expand Appalachia project team partners are:

  • Virginia Tech
  • University of Kentucky
  • Penn State
  • West Virginia University
  • Bluefield State University
  • Marshall Miller & Associates
  • Bandy Geological
  • Virginia Department of Energy
  • Kentucky Geological Survey
  • Crescent RI
  • Chmura Economics & Analytics
  • Gray Energy
  • Coalfield Strategies
  • US Geological Survey

“For many years, the Virginia Tech Mining and Minerals team has been a national leader in the area of rare earth and critical mineral production and is committed to work that improves the lives of our friends and neighbors through Appalachia,” notes Aaron Noble, Department Head of Mining and Minerals Engineering and project co-principal investigator. “I am excited to see how this new project will advance our efforts and expand our opportunities to secure domestic production of these critical resources.”

“It is crucial to our national and economic security that the U.S. identify secure sources of critical minerals. I am proud to see Virginia Tech playing a leading role in critical minerals research, leveraging natural resources found right here in the commonwealth.”

 -U.S. Sen. Mark Warner

"Critical minerals are essential for many of today’s technologies, especially those related to clean energy. I’m glad Virginia Tech is receiving federal funding I helped secure to research critical mineral extraction and processing in the Appalachian region. This will provide opportunities for new industries to develop, which will grow the local economy."

-U.S. Sen. Tim Kaine

“The work at the Virginia Center for Coal and Energy Research has led to exciting breakthroughs in tapping from coal beds sources of the rare earth minerals so integral to modern technology, used in everything from advanced batteries to smartphones. DOE’s award advances research that could support jobs in Appalachia and shore up supply chains vital to our country’s security and economic growth.”

- U.S. Rep. Morgan Griffith