Tuesday, November 15, 2022

A top investor is now taking aim at Alphabet, saying it has too many employees, pays them too much, and it’s burning money on bad bets.

Lakshmi Varanasi
Tue, November 15, 2022

Major Alphabet investor TCI sent a letter to Alphabet's CEO Sundar Pichai on Tuesday.

The letter urged the company to cut costs in part by reducing headcount and lowering compensation.

It also called for losses to be "reduced dramatically" in Waymo, Alphabet's self-driving car unit.


TCI Fund Management, one of Alphabet's top investors, sent a letter to the company on Tuesday urging it to slash costs by reducing headcount, lowering worker compensation, and curbing losses in long term bets like Waymo, its self-driving car unit.

The letter noted that "the cost base of Alphabet is too high and management needs to take aggressive action."



Google CEO Sundar Pichai speaking during a Google event in California in 2016.
Justin Sullivan/Getty Images

The London-based hedge fund has been a major stakeholder in Alphabet since 2017, and said its total shares in the company stack up to $6 billion. Despite the scale of its investments in Alphabet, the Wall Street Journal noted that it is "rare for big technology companies to face campaigns from activists such as TCI."

The letter was addressed directly to Alphabet's CEO Sundar Pichai from TCI's managing director, Christopher Hohn, who is known in institutional investment circles for his activism.


TCI's Christopher Hohn.
Peter MacDiarmid/ Getty Images

Hohn noted that TCI was particularly concerned with how bloated Alphabet had gotten over the years. According to TCI's calculations, which were illustrated via color-coded graphs, the company's headcount has grown at a rate of 20% per year since 2017.

Over that time, Alphabet's employees have more than doubled from just above 80,000 to close to 190,000.

"The company has too many employees and the cost per employee is too high," Hohn advised.

"It's a poorly kept secret in Silicon Valley that companies ranging from Google to Meta to Twitter to Uber could achieve similar levels of revenue with far fewer people," Hohn added, quoting Silicon Valley investor Brad Gerstner. He also noted that TCI had held conversations with former Alphabet executives.

TCI was not only vexed by Alphabet's headcount, but also by the company's above-market compensation rates. Hohn pointed out that median compensation at Apple was 153% higher than the 20 largest listed companies in the country.

"We acknowledge that Alphabet employs some of the most talented and brightest engineers, but these represent only a fraction of the employee base. Many employees are performing general sales, marketing and administrative jobs, which should be compensated in-line with other technology companies," Hohn wrote.

Alphabet has announced that it would be pulling back on hiring this year amidst increasing losses. However, it has yet to join fellow tech giants like Meta, Twitter, and Amazon who have or are planning to institute massive layoffs this year.

At the same time, Pichai has echoed TCI's sentiments on employee productivity. At an all-hands meeting in August, he reportedly told employees that "there are real concerns that our productivity as a whole is not where it needs to be for the headcount we have."

TCI concerns, however, extended beyond Alphabet's over-compensated and underperforming employees.

The fund called for the company to reduce its losses in Other Bets, its division where it invests in early stage projects that have the potential to bring in big returns, like Waymo, biotech company Calico, and later-stage venture firm CapitalG.

The payoff, however, has been underwhelming. In late October, the company reported $4.5 billion in losses from "Other Bets."

TCI specifically pushed Alphabet to cull its investment in Waymo. "Unfortunately, enthusiasm for self-driving cars has collapsed and competitors have exited the market," Hohn wrote. "Waymo has not justified its excessive investment and its losses should be reduced dramatically."

Alphabet did not immediately respond to Insider's request for a comment.

Investor TCI urges Alphabet to cut excessive headcount, costs


Tue, November 15, 2022 

 Letters spell the word "Alphabet" as they are seen on a computer screen with a Google search page in this photo illustration taken in Paris

(Reuters) - Activist investor TCI Fund Management has called on Alphabet Inc to cut costs by lowering its headcount and reduce losses in its self-driving unit Waymo, saying the Google parent needs to adjust to an era of slower growth.

The fund, an investor in Alphabet since 2017 with a $6 billion stake, said the company had "too many employees and cost per employee is too high".

TCI said Alphabet pays some of the highest salaries in Silicon Valley, noting that the company has increased headcount by 20% annually since 2017 and more than doubled it since then.

Alphabet did not immediately respond to a Reuters request for comment.

Shares of Alphabet, which has a market capitalization of $1.24 trillion, were up nearly 5% in mid-day trading.

Many tech companies including Meta Platforms Inc are lately making deep cuts to their employee base as part of its restructuring efforts to navigate a potential downturn in the economy, after years of rapid hiring.

Alphabet, which is also struggling with advertisers cutting back on spending, said in late October that it plans to cut hiring by more than half.

"Cost discipline is now required as revenue growth is slowing. Cost growth above revenue growth is a sign of poor financial discipline," the fund said in the letter to Alphabet's management and board.

TCI also called on Alphabet to disclose operating profit margin targets and reduce losses in Other Bets, the unit that includes Waymo and other special projects.

Investments into Waymo were not justified and losses should be reduced "dramatically," TCI said, adding that the autonomous vehicle technology unit has generated $3 billion but recorded operating losses of $20 billion so far. TCI demanded the unit reduce operating losses by at least 50%.

(Reporting by Tiyashi Datta and Nivedita Balu in Bengaluru; Editing by Shailesh Kuber)

In utero exposure to flame retardants increases anxiety symptoms in adolescents

University of Cincinnati-led research published in Depression & Anxiety journal

Peer-Reviewed Publication

UNIVERSITY OF CINCINNA

Jeffrey Strawn 

IMAGE: JEFFREY STRAWN, MD. view more 

CREDIT: PHOTO/COLLEEN KELLEY/UC MARKETING + BRAND.

New research led by the University of Cincinnati and Cincinnati Children’s Hospital Medical Center sheds light on the connection between exposure to environmental toxins in utero and the later development of anxiety during adolescence.

Lead author Jeffrey Strawn, MD, and his colleagues recently published the study in the journal Depression & Anxiety.

Strawn said researchers are increasingly interested in learning more about risk factors for anxiety and depression in children, particularly since there has been a surge of these symptoms during the pandemic. Even prior to the pandemic, anxiety disorders were among the most prevalent and earliest presenting mental health conditions for children, he said.

“We know a lot about early risk factors, including psychological risk factors, temperament, behaviors and family relationships,” said Strawn, professor in the Department of Psychiatry and Behavioral Neuroscience in UC’s College of Medicine and a UC Health child and adolescent psychiatrist. “But we know incredibly little about the effects of environmental factors like air pollution and other environmental toxicants on anxiety.”

The study focused on a class of chemicals called polybrominated diphenyl ethers (PBDEs) that were used as flame retardants for products like furniture foam padding, wire insulation, rugs, upholstery, computers and appliances. Exposure to PBDEs during early brain development has been associated with cognitive deficits, reduced language skills and attention-deficit/hyperactivity disorder, and the chemicals were banned in the United States in 2004.

Despite the ban, Strawn said exposure to PBDEs remains common, but its effect on anxiety symptoms had not been previously studied.

“One of the things that we know is that brain development starts relatively early in utero,” he said. “We wanted to look at how different exposures at different points in a pregnancy impact brain development and how that potentially translates to a risk for anxiety or depression symptoms, which we know tend to manifest a bit later. The idea is to look at what is the earliest risk factor that we can really identify.”

The researchers used data from the Health Outcomes and Measures of the Environment (HOME) study, which was designed to measure the impact of fetal and early childhood exposures to environmental toxicants like lead, mercury, pesticides, PBDEs and more. The study enrolled 468 pregnant women in the Greater Cincinnati region from 2003-2006 and continued to follow up with their children up to 12 years later.

“We have this ongoing sample with lots of data about the moms and specifically about their environmental exposures in terms of blood that was obtained during their pregnancy,” Strawn said. “What we did is look at the relationship between exposure to those different environmental chemicals, specifically flame retardants, and that subsequent risk of developing anxiety or having anxiety symptoms.”

A total of 236 adolescents from the HOME study were given self-reporting anxiety and depression screenings around the age of 12. 

The study found that each time the PBDE levels doubled in a pregnant mother’s blood sample was associated with increased anxiety scores in the adolescents, suggesting PBDE exposure during pregnancy may be a risk factor for developing anxiety symptoms in early adolescence. 

Strawn said it is important to note that an increase in anxiety symptoms does not necessarily correlate with the adolescents developing anxiety disorders, but PBDE exposure across an entire population could still have a large impact. 

“When you look at a population level and you see the effect of these ubiquitous chemicals increasing your baseline anxiety by 10% or 20%, that’s really significant across the whole population,” Strawn said. “That increase in anxiety across a population means that many individuals may cross the line between having manageable anxiety and having an anxiety disorder.”

Moving forward, Strawn said further research will aim to understand what brain regions are being affected by PBDE exposure and if there are certain time periods in pregnancy that are more closely associated with the increased anxiety risk. Work will also continue in improving clinical interventions and working to minimize PBDE exposure. 

Funding for this project was provided by the National Institute of Environmental Health Sciences (R01 ES11261, R01 ES020349, R01 ES027224). 

Strawn has received research support from the National Institutes of Health (NIMH/NIEHS/NICHD), Patient-Centered Outcomes Research Institute and AbbVie. He has received material support from and provided consultation to Myriad Genetics and provided consultation to the FDA, Intracellular Therapeutics and Cerevel. He receives royalties from the publication of two texts (Springer) and has provided CME lectures for Neuroscience Education Institute, Medscape and the American Academy of Pediatrics. He also receives research support from the Yung Family Foundation. 

The Great North and its challenges

An Annual Scientific Meeting

Meeting Announcement

ÉCOLE DE TECHNOLOGIE SUPÉRIEURE

Researchers from the Observatoire hommes-milieux International du Nunavik (OHMI) will meet on November 24 and 25, from 8 a.m. to 12 p.m (eastern time) via Zoom. They will present the results of seven research activities that were been launched to address issues arising from climate, ecological and social changes in the Arctic (see table below for the projects that will be presented).

Research themes include:

  • Industrial development, sustainable development and renewable energy sources
  • Food security and self-sufficiency
  • Inuit health and well-being and their relationship to the environment
  • Climate change, natural hazards and vulnerabilities of users of Nunavik parks, protected areas and cultural sites
  • Traditional knowledge, heritage, intergenerational discussions and Inuit perception of their territory

Inscription 

Interested in attending these discussions (in French only)? Write to didier.haillot@etsmtl.ca from the Department of Mechanical Engineering at École de technologie supérieure (ETS Montreal).

About OHMI-Nunavik

This group was created on the initiative of the Centre national de recherche scientifique (CNRS) (France) and Centre d'études nordiques (CEN) (Quebec) research institutes, and the communities residing in Nunavik who wish to take control of the development and management of their territory, particularly in a context where the Arctic is undergoing climate, ecological and social changes.

Program 

Project Nuna 
Fabienne Joliet, Laine Chanteloup, Thora Herrmann, Daniel Chartier, Véronique Coxam

Project Siqiniq 
Stéphane Gibout, Didier Haillot, Paul Piché, Danielle Monfet, Cedric Arrabie, Jasmin Raymond, Timothée Maheux, Robin Chaubier

Project Kinngaq
Armelle Decaulne, Najat Bhiry, Beatriz Funatsu

Project U-Scan
Véronique Coxam, Danielle Cloutier, Julien Gigault, Charlotte Carrier-Belleau, Fabienne Joliet, Laine Chanteloup, najat Bhiry, Armelle Decaulne

Project Takujuq
Armelle Decaulne, Daniel Germain, Fabienne Joliet, Laine Chanteloup, Thora Herrmann

Project HYDECO
Laurent Godet, Nicolas Lecomte


CHOP researchers find financial strain due to COVID-19 pandemic took significant toll on adolescent mental health

Study found the impact was most significant on low-income adolescents, but the effect was also seen across incomes, highlighting financial stress as a youth mental health risk factor

Peer-Reviewed Publication

CHILDREN'S HOSPITAL OF PHILADELPHIA

Ran Barzilay 

IMAGE: SENIOR AUTHOR RAN BARZILAY, MD, PHD, CHILD PSYCHIATRIST AND AN ASSISTANT PROFESSOR AT THE LIFESPAN BRAIN INSTITUTE (LIBI) OF CHILDREN’S HOSPITAL OF PHILADELPHIA (CHOP) AND THE PERELMAN SCHOOL OF MEDICINE AT THE UNIVERSITY OF PENNSYLVANIA view more 

CREDIT: CHILDREN'S HOSPITAL OF PHILADELPHIA

Philadelphia, November 15, 2022—Financial stress due to the COVID-19 pandemic took a distinct toll on adolescent mental health and contributed to depressive symptoms, according to a new study by researchers at Children’s Hospital of Philadelphia (CHOP). The study, published today in The Lancet Regional Health – Americas, found the effect was most pronounced in low-income adolescents but also affected all income groups who experienced financial strain due to loss of income.

“People often think children do not feel or understand financial stress, but this study shows not only that they do, but that this stress also takes a toll on their mental health,” said senior author Ran Barzilay, MD, PhD, child psychiatrist and an assistant professor at the Lifespan Brain Institute (LiBI) of Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania. “Given the strain inflation is likely placing on families’ finances, our findings underscore that financial stress is a key risk factor for adolescent mental health during economic crises and that addressing this stress is important given the current global youth mental health crisis.”

The COVID-19 pandemic has had a tremendous impact on global public health, but it has also contributed to a global economic crisis, which has both exacerbated financial issues in struggling families and introduced newfound financial strain to many others. Prior research at CHOP and LiBI has shown an association between pandemic-associated income loss and financial stress and depressive symptom in adults. However, despite an ongoing global youth mental health crisis, there previously was little data on the impact of financial stress on adolescent mental health.

To better understand this relationship, the CHOP researchers analyzed data from 9,720 adolescents who were a part of the Adolescent Brain Cognitive Development Study (ABCD Study®), a diverse sample of more than 10,000 U.S. children between the ages of 11 and 14. The researchers investigated the specific association of financial strain with adolescent mental health between May 2020 and May 2021. All participants had pre-pandemic data on household income and mental health.

The researchers found that adolescents whose families lost wages due to the pandemic were more likely to be Black (19.5% vs. 12.2%), Hispanic (22.0% vs. 12.9%), and below the poverty line (15.2% vs 4.2%) than those who did not. Those groups also expressed greater levels of stress about the financial impacts of the pandemic. Both pandemic-related wage loss and financial stress were more prevalent among youth with lower pre-pandemic household income – in other words, the poor were more likely to become poorer, with greater negative impacts on mental health. 

Youth from families who lost wages, regardless of pre-pandemic income, reported more depressive symptoms compared to those from families who did not lose wages; they also reported experiencing more perceived stress. The association between financial stress and depressive symptoms was significant even when accounting for pre-pandemic mental health. 

In addition to establishing an association between financial stress and depressive symptoms, the researchers also wanted to better understand the mechanics of how wage loss contributes poor adolescent mental health. To do so, they analyzed longitudinal data to identify factors that mediate the path from household pandemic-related wage loss at the beginning of the pandemic to youth’s depressive symptoms a year later. They found that both the youth’s subjective financial stress as well as family conflict contributed to poor adolescent mental health, suggesting that financial hardship impacts children and adolescents through a complex network of indirect pathways.

“Although this research focused specifically on pandemic-related wage loss, we suspect financial strain is a broader mental health risk factor for children and adolescents that is relevant during any time of economic uncertainty,” Dr. Barzilay said. “Future studies should look at targeting youth’s financial stress and family conflict to ease the mental health impact of difficult financial circumstances.”

Argabright et al. “COVID-19-related financial strain and adolescent mental health,” The Lancet Regional Health – Americas, November 15, 2022, DOI: https://doi.org/10.1016/j.lana.2022.100391.

#

About Children’s Hospital of Philadelphia: A non-profit, charitable organization, Children’s Hospital of Philadelphia was founded in 1855 as the nation’s first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals, and pioneering major research initiatives, the 595-bed hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country. The institution has a well-established history of providing advanced pediatric care close to home through its CHOP Care Network, which includes more than 50 primary care practices, specialty care and surgical centers, urgent care centers, and community hospital alliances throughout Pennsylvania and New Jersey, as well as a new inpatient hospital with a dedicated pediatric emergency department in King of Prussia. In addition, its unique family-centered care and public service programs have brought Children’s Hospital of Philadelphia recognition as a leading advocate for children and adolescents. For more information, visit http://www.chop.edu.

 

Traffic congestion may contribute to lower birthweight

A new study has found that stop-and-go traffic may be linked to reduced birthweight, and as many as 1.3 million pregnant people are exposed to this congestion each year.

Peer-Reviewed Publication

BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH

Copious data underline the adverse health effects of vehicle-related air pollution, but there is limited research on how bottleneck traffic, in particular—rather than overall traffic volume—can lead to negative health outcomes.

Now, a new study led by a Boston University School of Public Health (BUSPH) researcher has found that traffic congestion may be linked to lower birthweights.

Published in the journal Science Advances, the study found consistent associations between traffic delays and a nine-gram reduction in birthweight among infants born to parents who reside in areas with heavy traffic, such as highways or freeways. More than 11 million people live within 150 meters of highways, and the study results showed that up to 1.3 million pregnant people, representing 27 percent of US births, may be exposed to high levels of traffic congestion annually.

“For years, we’ve had detailed models to predict air pollution, but these models largely omit traffic congestion – because it could not be measured at a large scale,” says study lead and corresponding author Dr. Mary Willis, assistant professor of epidemiology at BUSPH. “If there are 10,000 vehicles on a road doing stop-and-go traffic, the air pollution concentrations, and likely composition, is very different compared to 10,000 vehicles at free-flow speeds. Our results show that there are likely health impacts specific to congestion, which are not included in most environmental risk assessments or cost-benefit analyses—and we think that those should start to be included in the conversation.”

Traffic delays have risen steadily across the country since 1982, and the researchers chose to examine potential links to low birthweight because it can lead to immediate and long-term consequences, such as difficulty breathing, cardiovascular disease, cognitive impairment, and premature mortality.

This study is the first to examine the impact of congestion on birth outcomes, in part due to challenges measuring traffic delays in large geographic areas. Willis and colleagues utilized almost 580,000 birth certificates in Texas and measured congestion levels through data from connected vehicles and devices that reflect actual driving volumes and speed. After controlling for background air pollution levels, transportation noise, and other environmental co-exposures, the results also indicated that mothers who lived closer to highways and freeways experienced slightly larger impacts from traffic jams, with 260,000 pregnancies occurring in the highest-congestion areas.

While a nine-gram reduction in weight is a relatively small decrease, the researchers say this finding lends important implications for population and environmental health.

“A nine-gram decrease alone isn’t a clinically significant result on its own, but this result indicates that some sort of biological impacts may be happening, which will push some babies into a clinically relevant adverse impact of low birth weight,” Willis says. “When you multiply that by 27 percent of all births being in high-congestion areas, that small decrease in birthweight does translate into a substantial potential impact at the population level.”

This data can also inform congestion-related policies and programs, which occur at the local level, unlike tailpipe emissions, which are primarily regulated at the federal level. The researchers note that stop-and-go traffic further increases air pollution through the extra wear on the brakes and tires, so reducing emissions from gas-powered cars won’t fully eliminate the hazards of congestion.

“Existing work shows that small changes to the local environment can reduce air pollution concentrations in nearby areas,” Willis says. “It can be as simple as putting up sound barriers or vegetation barriers; or using zoning approaches, and saying you can’t build a school or a daycare within a specific distance of a highway. More complex solutions may include traffic control measures such as electronic tolling or congestion pricing.”

In future work, the team plans to study the socioeconomic and racial disparities in exposures to traffic congestion, particularly how disparities may have changed over time from urbanization and gentrification in metropolitan areas.

***

About Boston University School of Public Health
Founded in 1976, Boston University School of Public Health is one of the top five ranked private schools of public health in the world. It offers master's- and doctoral-level education in public health. The faculty in six departments conduct policy-changing public health research around the world, with the mission of improving the health of populations—especially the disadvantaged, underserved, and vulnerable—locally and globally.

 

PRISON NATION U$A

Incarceration of parent is associated with worse access to health care for millions of US children, new study shows

Peer-Reviewed Publication

ANN & ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO

According to a new study, children exposed to parental incarceration had worse access to primary care and more unmet dental and mental health care needs than their peers, even after accounting for income, insurance status, rurality, and other important factors. With the United States having the highest incarceration rate in the world, these barriers currently place more than 5 million children who have experience the incarceration of a parent at risk of worse mental and physical health outcomes because of poor access to early health interventions.

The study was published in Academic Pediatrics and authored by Drs. Rohan KhazanchiNia Heard-Garris, and Tyler Winkelman from Boston Children’s Hospital/Boston Medical Center, Ann & Robert H. Lurie Children’s Hospital of Chicago, and Hennepin Healthcare, respectively. The researchers evaluated the relationships between having an incarcerated parent and health care use and access throughout childhood and adolescence.

“Exposure to parental incarceration is a key adverse childhood experience with physical and mental health impacts across the course of the lives of these kids,” Dr. Heard-Garris from Lurie Children’s explains. “They are exposed to nearly five times as many adverse childhood experiences as their peers, and we know that is also unfortunately associated with increased incidence of learning and developmental disabilities, physical health conditions, and mental health conditions in adulthood.”

Parental incarceration is also disproportionately concentrated among Black, poor, and rural children. The inequitable and racialized distribution of parental incarceration can lead to other adverse exposures, including child poverty.

“While children and adolescents are living with their other parent or caregiver, parental incarceration can disrupt access to care for them through the loss of health insurance and fewer caregivers to help with responsibilities like routine healthcare visits,” explains Dr. Winkelman, the senior author of the study.

The study’s findings support structural interventions to address care disruption from childhood to early adulthood among individuals exposed to parental incarceration. This spans multiple levels of intervention, including clinical screening tools, institutional efforts to support families and communities impacted by incarceration, and policy interventions to improve access to care for this marginalized population of children.  

“Adverse childhood experiences like parental incarceration are not just isolated experiences—they are symptoms of broader structural challenges,” said Dr. Rohan Khazanchi, the study’s lead author. “Health and social service organizations should address parental incarceration as a public health issue by developing programs to support families during and after periods of parental incarceration, so that children aren’t penalized. Leaders in the criminal-legal system should also recognize the impact of their sentencing decisions on whole families and identify opportunities to minimize the negative consequences for children—including, when possible, decarceration.”

Suggested approaches at jails and prisons to help support families include offering training for staff on the impact of parental incarceration on children and families, ensuring parental needs are assessed at intake, linking impacted families to community resources, supporting family-friendly visits between parents, their children, and systems that impact their children (for example, their children’s teachers), implementing evidence-based parent management training programs, involving caregivers in facility programming, and including caregivers and children in reentry planning.

The study authors conclude that trauma-informed, cross-sector partnerships between jails, prisons, policymakers, and clinicians are needed to reduce the life-changing impacts of incarceration on future generations.  

Boston Children’s Hospital/Boston Medical Center
Boston Medical Center (BMC) is a private, not-for-profit, 514-bed, academic medical center that is the primary teaching affiliate of Boston University Chobanian & Avedisian School of Medicine. It is the largest and busiest provider of trauma and emergency services in New England. BMC offers specialized care for complex health problems and is a leading research institution, receiving more than $110 million in sponsored research funding in fiscal year 2021. It is the 13th largest funding recipient in the U.S. from the National Institutes of Health among independent hospitals. WellSense Health Plan was founded in 1997 as Boston Medical Center HealthNet Plan, now one of the top ranked Medicaid MCOs in the country, as a non-profit managed care organization. Boston Medical Center and Chobanian & Avedisian SOM are partners in Boston HealthNet – 12 community health centers focused on providing exceptional health care to residents of Boston. For more information, please visit http://www.bmc.org.

Lurie Children’s Hospital
Research at Ann & Robert H. Lurie Children’s Hospital of Chicago is conducted through Stanley Manne Children’s Research Institute. The Manne Research Institute is focused on improving child health, transforming pediatric medicine and ensuring healthier futures through the relentless pursuit of knowledge. Lurie Children’s is ranked as one of the nation’s top children’s hospitals by U.S. News & World Report. It is the pediatric training ground for Northwestern University Feinberg School of Medicine.

Hennepin Healthcare
Hennepin Healthcare is an integrated system of care that includes HCMC, a public acute care, research, and teaching hospital. The Hennepin Healthcare Research Institute is Minnesota’s third-largest non-profit medical research organization.  It ranks in the top 10 percent of all institutions receiving research funding from the National Institutes of Health. 

Welsh “weird wonder” fossils add piece to puzzle of arthropod evolution

Peer-Reviewed Publication

HARVARD UNIVERSITY, DEPARTMENT OF ORGANISMIC AND EVOLUTIONARY BIOLOGY

Welsh. 

IMAGE: ARTISTIC RECONSTRUCTION OF THE ORDOVICIAN FOSSILS MIERIDDURYN BONNIAE view more 

CREDIT: ORIGINAL ARTWORK BY FRANZ ANTHONY

The most famous fossils from the Cambrian explosion of animal life over half a billion years ago are very unlike their modern counterparts. These “weird wonders,” such as the five-eyed Opabinia with its distinctive frontal proboscis, and the fearsome apex predator Anomalocaris with its radial mouthparts and spiny feeding appendages, have become icons in popular culture. However, they were only quite recently recognised as extinct stages of evolution that are crucial for understanding the origins of one of the largest and most important animal phyla, the arthropods (a group that includes modern crabs, spiders, and millipedes).

In an article published today in Nature Communicationstwo new specimens with striking similarities to Opabinia are described from a new fossil deposit recording life in the Ordovician Period, 40 million years after the Cambrian explosion. This deposit, located in a sheep field near Llandrindod Wells in mid Wales (UK), was discovered during the COVID-19 lockdowns by independent researchers and Llandrindod residents Dr Joseph Botting and Dr Lucy Muir, Honorary Research Fellows at Amgueddfa Cymru - National Museum Wales.

The quarry is well known as one of several local sites yielding new species of fossil sponges. “When the lockdown started, I thought I'd make one more trip to collect some last sponges before finally writing them up,” said Botting, “of course, that was the day that I found something sticking its tentacles out of a tube instead.”

“This is the sort of thing that palaeontologists dream of, truly soft-body preservation,” said Muir, “we didn't sleep well, that night.” That was the beginning of an extensive and ongoing investigation that grew into an international collaboration, with lead author Dr Stephen Pates (University of Cambridge) and senior author Dr Joanna Wolfe (The Department of Organismic and Evolutionary Biology at Harvard University).

 Among the fossils unearthed so far are two very unexpected leftovers from the Cambrian “weird wonders.” Pates met with Botting and Muir to study the specimens using microscopes purchased through crowd-funding to examine the tiny specimens. The larger specimen measured 13 mm, while the smaller measured a miniscule 3 mm (for comparison Opabinia specimens can be 20 times as long).

Exhaustive studies during this visit revealed additional details in the new specimens. Some of these features are also found in Opabinia, such as triangular, squishy lobopod ‘legs’ for interacting with the sediment, and—in the smaller specimen – a tail fan with blades similar in shape to Opabinia’s recently described sister, Utaurora. However other features recognised in the material, such as sclerites covering the head as well as the presence of spines on the proboscis, were not known from any opabiniid and instead hinted at possible radiodont (including Anomalocaris) affinities. The differences between the two specimens led the researchers to wonder were these due to changes during the growth of one species, or did they instead suggest that two distinct species were present in this new deposit?

The authors describe the new taxon, Mieridduryn bonniae, with the larger specimen designated the holotype. The status of the smaller specimen was left open, reflecting these different possibilities. “The size of the smaller specimen is comparable to some modern arthropod larvae – we had to take into account this possibility in our analyses,” said Wolfe.

The genus name Mieridduryn is derived from the Welsh language, and translates as “bramble-snout,” reflecting the spiny proboscis in the new material. It is pronounced like “me-airy-theerin”. “Many scientific names are made using Latin or Greek words,” Muir said, “but we really wanted to honour Wales, where the specimens were discovered, and so chose to use the Welsh language.” The species name bonniae pays tribute to the niece of the landowners, Bonnie. “The landowners have been very supportive of our research, and Bonnie has been avidly following our progress, even attending some of our Zoom updates,” said Botting.

The researchers used phylogenetic analyses, comparing the new fossils with 57 other living and fossil arthropods, radiodonts, and panarthropods, to determine their place in the history of arthropod evolution. “The best-supported position for our Welsh specimens, whether considered as one or two species, were more closely related to modern arthropods than to opabiniids. These analyses suggested that Mieridduryn and the smaller specimen were not “true” opabiniids,” said Pates.

Crucially, these results suggested that a proboscis—thought to represent a fused pair of head appendages—was not unique to opabiniids, but instead was present in the common ancestor of radiodonts and deuteropods (more derived, modern arthropods), and through evolutionary time may have reduced to become the labrum that covers the mouth in modern arthropods. However, the second-best-supported position for these specimens was as true opabiniids, so the authors enquired a bit further to test the robustness of this first result.

“These Welsh animals are 40 million years younger than Opabinia and Utaurora” said Wolfe, “so it was important to assess the implications of some features, such as spines on the appendages or a carapace, evolving convergently with radiodonts in our analyses.” If some, or all, the features shared between the Welsh animals and radiodonts were instead considered to have evolved convergently, the analyses strongly favoured these specimens being considered true opabiniids, the first from outside North America and the youngest by 40 million years. Whatever the eventual conclusion, the fossils are an important new piece in the arthropod evolutionary jigsaw.

These small but scientifically mighty fossils are some of the first findings from this important new Ordovician fauna. Botting and Muir continue their work in the small quarry in the sheep field with more still to come. Muir added, “Even the sheep know we are on to something special here, they usually come to watch.”

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Contributors to the crowdfunding appeal to purchase the microscopes (including a Holloway Bursary from the Warwickshire Geological Conservation Society) are gratefully acknowledged. Additional funding was provided by a University of Cambridge Herchel Smith Postdoctoral Fellowship, Chinese Academy of Sciences PIFI fellowships (2020VCB0014 and 2018VCB0014). This work was also supported by the National Science Foundation DEB #1856679.

The specimen is accessioned at Amgueddfa Cymru—National Museum Wales.

Announcing the 2022 SETI Forward Recipients

SETI Forward fosters the next generation of scientists pursuing careers in SETI and astrobiology.

Grant and Award Announcement

SETI INSTITUTE

Benjamin Fields 

IMAGE: BENJAMIN FIELDS view more 

CREDIT: SETI INSTITUTE

November 9, 2022, Mountain View, CA – The SETI Institute is announcing the 2022 recipients of its SETI Forward Award, recognizing outstanding undergraduate interns studying astrobiology and SETI research: Benjamin Fields (Wheaton College), Ze-Wen Koh (Cornell University) and Lana Tilke (Connecticut College). The SETI Forward award provides scholarship funds to support the next generation of scientists pursuing SETI and astrobiology career opportunities and connects promising students with researchers.

"The 2022 SETI Forward applications were the most diverse and qualified applicants we've ever had representing nations and institutions from around the globe," said Lew Levy, founder and chair of the SETI Forward committee, long-time SETI Institute supporter and member of its Council of Advisors. “It is great to see the progression of people entering the fields of SETI and astrobiology." Levy conceived of the idea of SETI Forward through his involvement with interns at Berkeley Center Research Cwenter and partnered with SETI Institute trustee Dane Glasgow to establish the award.

The SETI Forward award was launched in 2018 to support undergraduate students interested in pursuing careers in SETI and astrobiology. Each year, dozens of students intern with the SETI Institute and other universities and science institutes, but many pivot to other fields, resulting in fewer talented researchers focused on the search for life beyond Earth. SETI Forward aims to help bridge the gap between their internships, graduate school, and jobs by providing stipends to facilitate research collaborations or participation in scientific conferences.

Benjamin Fields
Benjamin attends Wheaton College and did his internship at Wheaton. His research focused on archival data Optical SETI. Specifically, he surveyed spectra taken by the European Southern Observatory’s (ESO) High Accuracy Radial velocity Planet Searcher (HARPS) spectrograph to see if it may have captured evidence of laser communications from extraterrestrial civilizations. Since HARPS is not primarily used to look for intelligently produced signals, there may be unnoticed technosignatures in the archived data. Ben wrote an algorithm that searched for anomalous energy spikes in the spectra of 2,821 stars that flagged candidate signals for follow-up investigation. He compared these strange energy spikes to natural stellar emission lines, signatures of the Earth's aurorae, and cosmic rays bombarding the CCD to ascertain whether they are natural or potentially extraterrestrial in origin. Ultimately my goal is to share it with the technosignature research community, and the SETI Forward Award gives me an excellent opportunity to do so!

“The search for extraterrestrial life is my greatest passion and has been for as long as I can remember,” said Fields. It remains one of the biggest fundamental questions we might answer with the tools of science, and one which I hope to dedicate myself to advancing. The SETI Forward Award represents an unparalleled opportunity to carve out this path, and I am honored to receive it.”

Ze-Wen Koh
Ze-Wen attends Cornell University and did her internship at Cornell. The main idea driving her work is that Europa's seafloor topography could reveal information about the nature of Europa's geologic activity, which may manifest in the form of active volcanism or hydrothermal circulation at its seafloor. Ze-Wen created a suite of models to determine whether the topography of Europa's seafloor will be detectable from the upcoming Europa Clipper mission's gravity science experiments. She also modeled Europa's seafloor scaled from other geologically active bodies such as Earth, Venus and Io to determine how detectable volcanism and plate tectonics would be at Europa. The team found, in general, that the coarse style of Europa's seafloor topography is indeed detectable from a gravity science experiment of Clipper's resolution and published the results in their paper. 

“Working on this project and receiving the SETI Forward award has affirmed that I'm working on valuable science in the search for life and that I have a place in this field,” said Koh. “I'm excited to contribute to a growing diversity of perspectives in astronomy and continue pursuing the question of dynamic habitability: how planetary surfaces, atmospheres and interiors evolve, and their resulting viability as hosts for life. After graduation, I hope to pursue a PhD in Planetary Science to further explore these research interests, followed by a career in academia or research.”


Lana Tilke

CREDIT

SETI Institute

Lana Tilke
Lana attends Connecticut College and did her internship at the University of California, Berkeley. She was mentored by Dr. Steve Croft and the SETI Institute’s Dr. Ann Marie Cody. Her research involved conducting machine learning-enabled follow-up on TESS data to search for anomalies potentially indicative of technological megastructures.

“As a lifelong science fan, both factual and fictional, working in the field of SETI has been a goal of mine ever since I participated in Zooniverse’s Kepler Planet Hunters campaign as a child,” said Tilke. “I am honored for the support I have received from the SETI Institute and am eager to see where my career takes me, whether I become a research scientist, professor, science communicator, or all of the above!”

A diverse panel established by the SETI Forward Fund administration selects SETI Forward recipients. Undergraduates at accepted institutions participating in a mentored internship are eligible to apply.

The next generation of SETI and astrobiology scientists will develop new technologies and make discoveries we cannot even imagine today. The SETI Institute strives to foster future pioneers in SETI and astrobiology through educational programs and awards, such as SETI Forward.

The 2022 SETI Forward recipients will receive their awards at the next Drake Awards event in May 2023.

About the SETI Institute
Founded in 1984, the SETI Institute is a non-profit, multi-disciplinary research and education organization whose mission is to lead humanity’s quest to understand the origins and prevalence of life and intelligence in the Universe and to share that knowledge with the world. Our research encompasses the physical and biological sciences and leverages expertise in data analytics, machine learning and advanced signal detection technologies. The SETI Institute is a distinguished research partner for industry, academia and government agencies, including NASA and NSF.

Contact information
Rebecca McDonald
Director of Communications
SETI Institute
rmcdonald@seti.org