New evidence links passive smoking with dangerous heart rhythm disorder

EUROPEAN SOCIETY OF CARDIOLOGY

Berlin, Germany – 7 April 2024:  Exposure to secondhand smoke – even at small amounts – is linked with greater risk of a serious heart rhythm disorder, according to research presented at EHRA 2024, a scientific congress of the European Society of Cardiology (ESC).1 The likelihood of atrial fibrillation increased as the duration of passive smoking lengthened. 

“The dangers of secondhand smoke were significant regardless of whether individuals were at home, outdoors, or at work, indicating that exposure universally elevates the risk of atrial fibrillation,” said study author Dr. Kyung-Yeon Lee of Seoul National University Hospital, Seoul, Republic of Korea. “We should all make every effort to avoid spending time in smoky environments. The findings should also drive policymakers to further curb smoking in public areas and support smoking cessation programmes to improve public health.” 

Atrial fibrillation is the most common heart rhythm disorder worldwide.2 Symptoms include palpitations, shortness of breath, fatigue, and difficulty sleeping. It is estimated that one in three Europeans will develop the condition during their lifetime. People with atrial fibrillation are five times more likely to have a stroke than their healthy peers. 2 

It is well established that passive smoking is linked to coronary artery disease and premature death.3-8 However, the links between secondhand smoke and atrial fibrillation have been unclear. This study examined the association between secondhand smoke exposure and the long-term risk of incident atrial fibrillation. The study included adults aged 40 to 69 years who had used the UK National Health Service (NHS) for any reason and were enrolled in the UK Biobank. Current smokers and those with atrial fibrillation at baseline were excluded from the study. 

A total of 400,493 adults were included in the analysis. The average age of participants was 56.5 years and 55.2% were women. A touchscreen questionnaire was used to ask participants the number of hours they had been exposed to other people’s smoke in a typical week over the past year at home and in other environments. Participants were categorised into the ‘exposed group’ if they had any contact with secondhand smoke and the ‘non-exposed group’ if they had no contact with secondhand smoke. Some 85,984 (21%) participants had been exposed to secondhand smoke in the previous year, with an average exposure of 2.2 hours per week. During a median follow-up of 12.5 years, atrial fibrillation developed in 23,471 (6%) participants. 

The researchers analysed the association between exposure to secondhand smoke and incident atrial fibrillation after adjusting for factors that could potentially affect the relationship, including age, sex, ethnicity, body mass index, daily alcohol consumption, moderate-to-vigorous physical activity, diabetes, high blood pressure, high blood lipids, socioeconomic status, and enrolment centre. The group exposed to secondhand smoke had a 6% higher risk of incident atrial fibrillation during follow-up compared with the non-exposed group after adjusting for the previously mentioned factors (hazard ratio 1.06, 95% confidence interval 1.03–1.10, p <0.001). 

A dose-dependent relationship was observed, whereby each increase in the duration of weekly passive smoking was linked with an even greater risk of atrial fibrillation. For example, 7.8 hours of passive smoking per week was associated with an 11% higher likelihood of the heart rhythm disorder compared with no passive smoking. The risk of atrial fibrillation for passive smokers was raised in homes, workplaces, and outside spaces. 

Dr. Lee said: “According to our study, once exposed to secondhand smoke, the likelihood of developing atrial fibrillation begins to increase, with the risk escalating significantly as the exposure time lengthens. The finding that passive smoking is harmful not only in enclosed indoor spaces but also outdoor environments underscores the importance of smoking bans to protect public health.” 

 

ENDS 

 

Authors: ESC Press Office  
Tel: +33 (0)489 872 075 

Email: press@escardio.org 

Follow us on X @ESCardioNews  

 

Notes to editor 

 

Funding: None. 

Disclosures: None. 

 

References and notes 

1The abstract ‘Secondhand tobacco smoke and risk of atrial fibrillation: an observational epidemiologic and gene-environment interaction analysis’ will be presented during the session ‘Atrial fibrillation: basic science - epidemiology’ which takes place on 7 April 2024 at 08:30 CEST at Moderated ePosters 1. 

2Hindricks G, Potpara T, Dagres N, et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2020;42:373-498. 

3Yankelevitz DF, Cham MD, Hecht H, et al. The association of secondhand tobacco smoke and CT angiography-verified coronary atherosclerosis. JACC Cardiovasc Imaging. 2017;10:652-659. 

4Yankelevitz DF, Henschke CI, Yip R, et al. Second-hand tobacco smoke in never smokers is a significant risk factor for coronary artery calcification. JACC Cardiovasc Imaging. 2013;6:651-657. 

5Peinemann F, Moebus S, Dragano N, et al. Secondhand smoke exposure and coronary artery calcification among nonsmoking participants of a population-based cohort. Environ Health Perspect. 2011;119:1556-1561. 

6Gallo V, Neasham D, Airoldi L, et al. Second-hand smoke, cotinine levels, and risk of circulatory mortality in a large cohort study of never-smokers. Epidemiology. 2010;21:207-214. 

7Glantz SA, Parmley WW. Passive smoking and heart disease. Epidemiology, physiology, and biochemistry. Circulation. 1991;83:1-12. 

8Lv X, Sun J, Bi Y, et al. Risk of all-cause mortality and cardiovascular disease associated with secondhand smoke exposure: a systematic review and meta-analysis. Int J Cardiol. 2015;199:106-115. 

 

About the European Heart Rhythm Association 

The European Heart Rhythm Association (EHRA) is a branch of the European Society of Cardiology (ESC). Its aim is to improve patients’ quality of life and reduce sudden cardiac death by limiting the impact of heart rhythm disturbances.  

 

About the EHRA Congress     #EHRA2024 

EHRA 2024 is the annual congress of the European Heart Rhythm Association (EHRA) of the European Society of Cardiology (ESC). 

 

About the European Society of Cardiology  

The European Society of Cardiology brings together health care professionals from more than 150 countries, working to advance cardiovascular medicine and help people lead longer, healthier lives. 

 

Information for journalists about registration for EHRA 2024 

EHRA 2024 will be held 7 to 9 April at the CityCube Berlin, Germany, and online. Explore the scientific programme.

• Free registration applies to accredited press. 

• Credentials: A valid press card or appropriate letter of assignment with proof of three recent published articles. Read the ESC media and embargo policy. 

• The ESC Press Office will verify the documents and confirm by email that your press accreditation is valid. 

• The ESC Press Office decision is final regarding all press registration requests.