Prenatal exposure to fine particulate matter components and autism risk in childhood

JAMA Network Open

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About The Study: 

In this large cohort study, prenatal exposure to specific fine particulate matter (PM2.5) components and postnatal ozone (O3) exposure were associated with autism spectrum disorder risk. The second and third trimesters may represent sensitive exposure windows. These findings support further research on air pollution’s role in autism spectrum disorder etiology. 

Corresponding Author: To contact the corresponding author, Eric Lavigne, PhD, email eric.lavigne@hc-sc.gc.ca.

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(doi:10.1001/jamanetworkopen.2025.38882)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

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JAMA Network Open