Saturday, November 30, 2024






Lahore’s smog: the sun may be out but a sustainable solution remains out of sight

As Punjab eases restrictions, the lingering health crisis and calls for real environmental action expose a battle far from over.
Published November 29, 2024
  PRISM/DAWN

Atif Manzoor, 45, the owner of a blue pottery business in Multan, had every reason to feel cheerful last week when the sun finally came out. For a good three weeks, the city of Sufi shrines had been shrouded in an envelope of thick smog.

For over three weeks, he said, business had been terrible, with “several orders cancelled” and advance payments refunded. He also had to bear the transport costs he had already paid after the government imposed restrictions on heavy traffic and closed the motorways due to poor visibility.

Thick smog had blanketed cities across Punjab province, home to 127 million people, since the last week of October. Multan, with a population of 2.2 million, recorded an air quality index (AQI) above 2,000, surpassing Lahore, the provincial capital, where the AQI exceeded 1,000.

While Lahore’s AQI has improved, it still fluctuates between 250 (very unhealthy) and 350 (hazardous) on the Swiss company’s scale, keeping it among the top cities in the world with the poorest air quality. As this article went into publication, it was 477, or “very unhealthy.”

Terming the AQI levels in Punjab, in particular Lahore and Multan, “unprecedented”, Punjab’s Environment Secretary, Raja Jahangir Anwar, blamed the “lax construction regulations, poor fuel quality, and allowing old smoke-emitting vehicles plying on the roads, residue burning of rice crops to prepare the fields for wheat sowing” as some of the factors contributing to the smog in winter when the air near the ground becomes colder and drier.

Manzoor was not alone in his predicament. Smog had disrupted everyone’s life in the province, including students, office workers, and those who owned or worked in or owned smoke-emitting businesses like kilns, restaurants, construction, factories, or transport, after authorities put restrictions on them.

Even farmers in rural settings were not spared. Hasan Khan, 60, a farmer from Kasur, said that the lack of sunlight, poor air quality, transport delays preventing labourers from reaching farms, and low visibility were all hindering farm work and stunting crop growth.

“The smog hampered plant growth by blocking sunlight and slowing photosynthesis, and since we do flood irrigation, the fields stay drenched longer, causing crop stress, and the trees began shedding their leaves due to poor air quality,” he said.


A screenshot of the IQAir airquality index for Thursday, November 28, 2024, showing the top 10 most polluted cities. Credit: IQAir


Divine intervention or blueskying


After weeks of relentless smog, residents of Punjab had been calling for artificial rain, similar to what was done last year. This process involves releasing chemicals like silver iodide from airplanes to induce rainfall.

However, Anwar explained that artificial rain requires specific weather conditions, including the right humidity levels, cloud formations, and wind patterns. “We only carry out cloud seeding when there is at least a 50 per cent chance of precipitation,” he said.

On November 15, favourable weather conditions allowed for cloud seeding over several cities and towns in Punjab’s Potohar Plateau, leading to natural rainfall in Islamabad and surrounding areas. The forecast also predicted that this would trigger rain in Lahore.

On November 23, Lahore received its first winter rain, which helped clear the thick, toxic smog that had been causing eye irritation and throat discomfort, revealing the sun and a clear blue sky. However, some believe the downpour was the result of the collective rain prayer, Namaz-i-Istisqa, held at mosques across the province, seeking divine intervention.

But cloud seeding has its critics. Dr Ghulam Rasul, adviser at the China-Pakistan Joint Research Centre and former head of the Pakistan Meteorological Department, cautioned that cloud seeding might reduce smog temporarily, but it was not a sustainable solution. Instead, it could create dry conditions that worsen fog and smog. He also warned that an overdose could trigger hailstorms or heavy rainfall.

Once the smog thinned and the air quality improved, the government eased its restrictions, allowing shops and restaurants (with barbecues if smoke is controlled) to remain open till 8pm and 10pm, respectively; schools and colleges have also opened, and the ban placed on construction work, brick kiln operations, and heavy transport vehicles (carrying passengers, fuels, medicines, and foods), including ambulances, rescue, fire brigades, prison, and police vehicles, has also been lifted. In addition, the government has installed 30 air quality monitors around Lahore and other cities of the province.

While the air may have cleared, health issues left in its wake are expected to persist, according to medical practitioners. Over the past 30 days, the official score of people seeking medical treatment for respiratory problems in the smog-affected districts of the province reached over 1.8 million people. In Lahore, the state-owned news agency, the Associated Press of Pakistan, reported 5,000 cases of asthma.

“Frankly, this figure seems rather underreported,” said Dr Ashraf Nizami, president of the Pakistan Medical Association’s Lahore chapter.

“This is just the beginning,” warned Dr Salman Kazmi, an internist in Lahore. “Expect more cases of respiratory infections and heart diseases ahead,” he said.

Unicef had also warned that 1.1 million children under five in the province were at risk due to air pollution. “Young children are more vulnerable because of smaller lungs, weaker immunity, and faster breathing,” the agency stated.


While the government has put several measures in place, a long-term, measurable plan is needed, say experts. Credit: Hasan Khan


Ineffective band-aid solutions

Although the government took several measures to manage the smog, few were impressed. Climate governance expert Imran Khalid, blaming the “environmental misgovernance for degradation of an already poor air quality across Pakistan,” found the anti-smog plan a “hodgepodge of general policy measures” with no long-term measurable plan.

He argued that the plan only targets seasonal smog instead of taking a year-round “regional, collective approach” to fighting air pollution across the entire Indus-Gangetic plains, not just in Lahore or Multan.

“I will take this seriously when I see a complete action plan in one place, preceded by a diagnostic of the causes and followed by a prioritisation of actions with a timeline for implementation monitored by a committee with representation of civil society,” said Dr. Anjum Altaf, an educationist specialising in several fields along with environmental sciences. “Till such time, it is just words!” he added.

Khalid said plans and policies can only succeed if they are evidence-based, inclusive, bottom-up, and “and implemented by well-trained authorities, supported by political will and resources, flexible in response to challenges, and focused on the health of the people.”

Others argue that the slow response to the decade-long smog crisis, despite a clear understanding of its causes, reflects a matter of misplaced priorities.

“It’s all about priority,” said Aarish Sardar, a design educator, curator, and writer based in Lahore. “Many years ago, when the government wanted to nip the dengue epidemic, it was able to,” he said.

“Mosquitoes were eliminated once they reached officials’ residences,” said farmer Khan, agreeing that when there is political will, remarkable changes can occur.



Header image: Farmer Hasan Khan took photos of his farm in Kasur during the smog. Credit: Hasan Khan

This article was originally published in Inter Press Service and has been reproduced here with permission.


Zofeen T. Ebrahim is an independent journalist based in Karachi.
She tweets at @zofeen28.



Clean-up needed

 November 29, 2024


A POPULAR saying I have been hearing since childhood is: “Safaai nisf iman hai” (cleanliness is half the faith). Today, the ‘Queen of the East’, as Karachi was once dubbed by Sir Charles Napier, has lost its faith. It needs a good scrub.

When it comes to rankings, the city certainly flies high or trails far behind, whichever way you prefer to put it. Not too long ago, the Economist’s Intelligence Unit evaluated 173 cities in the world in terms of their livability. Environment and infrastructure were two factors among others that were taken into account. Karachi ranked 169th.

In terms of pollution by solid waste, the city has the worst record in the country. Solid waste makes the city unliveable and also has a negative aesthetic dimension. Karachi generates 16,500 tons of solid waste every day, but barely two-thirds of it is collected to be sent to the handful of landfill sites on the outskirts of the city. The remaining waste adorns street corners and open plots and can also be seen in the middle of the road. The Sindh Solid Waste Management Board set up in 2014 has failed to do its job. Its poor performance is on public display.

Not enough has been written about the impact of urban pollution on human heal­­th. Even the Pakistan Medical Asso­ciation seems to have resigned itself to people learning to live with urban waste in their vicinity. So focused is the medical profession on the curative approach that most of its practitioners fail to mention that a cleaner city would mean fewer illnesses and less out-of-pocket expenditure for patients.


They should also sort out the waste they generate in their homes.

One point of view is that the solid waste problem is a class issue. In his South Asian Idea (a web-based periodical) Anjum Altaf writes about the future of the city in South Asia. He does not hold out much hope for our cities: “…each South Asian city has split into two — the rich enclaves and the poor slums. At the same time, the discovery that disease is spread by germs not polluted air has shifted the focus from collective sanitation reforms to protection of the individual through immunisation. The rich have thus also isolated themselves from the diseases of the poor. As a result, there is no powerful lobby of influential citizens behind urban reform that benefits the entire city.”

He asks: “Is the South Asian city doom­­ed to a schizophrenic and split future?”

However, Karachi does not exactly fit this description. The metropolis is certainly divided into localities inhabited by people from different income groups. But these areas are not totally detached from one another. In fact, the more affluent among them are often ringed by squatters’ settlements that supply menial labour to serve rich households. Hence our society may be schizophrenic but not the city.

Defence Housing Authority, the most affluent and ostentatious of all residential areas, also has its share of solid waste heaps and dilapidated roads. The residents’ problems are no different from those of their kin in Nazimabad and Gulshan in this respect. The problems of the rich, however, are much smaller in size and complexity. Moreover, money solves a number of them. Still, the problems exist, testifying to the parity that marks Pakistanis’ temperament vis-à-vis ‘rubbish’.

From where do we begin Operation Clean-up? While the removal of primary waste from public collection points and transporting the solid waste to the dump is obviously the duty of the municipal authorities, the people also have a role to play. Our disregard for cleanliness in public places knows no class barriers. I have seen the richest of rich lower the window of their air-conditioned Pajero and hurl a bagful of kit­­­ch­­en waste towards a garbage can on the road corner. Needless to say, the aim was not perfect.

On their part, the people should help by not littering public places. They should also sort out the waste they generate in their homes into three categories: organic kitchen waste for composting, paper and glass for recycling, and plastic waste that is given a decent burial. The local government should take over at this point, and provide practical collection points from where the waste, sorted out, is carried to the correct destination.

Once I was told by my host in a Southeast Asian country that children taught the virtues of cleanliness in school learn fast. This practice teaches the child the dignity of labour as well. The only school in Karachi I know that does this is The Garage School that celebrated its silver jubilee last week. Its premises are spick and span as the students sweep their classrooms themselves. Other schools should be doing the same to create a vested interest in cleanliness in those who spend their time there.

www.zubeida-mustafa.com

Published in Dawn, November 29th, 2024

 

Generalizability of clinical trials of novel weight loss medications to the US adult population



JAMA Internal Medicine





About The Study: 

This study estimates that approximately one-third of U.S. adults without diabetes who were eligible for weight loss treatment with glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GLP-1/GIP) were excluded from clinical trials supporting these medications’ safety and effectiveness. Until there is evidence from high-quality postmarketing studies, the FDA should consider updating labeling to advise caution on generalizing the safety and effectiveness of GLP-1 and GLP-1/GIP to populations excluded from pivotal trials.



Corresponding Author: To contact the corresponding author, Timothy S. Anderson, MD, MAS, email tsander@pitt.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamainternmed.2024.6340)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2024.6340?guestAccessKey=f706964e-006e-4c93-9e47-75456cc57d5f&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=112524

 

 

ODS FeCrAl alloys endure liquid metal flow at 600 °C resembling a fusion blanket environment



Scientists examined the chemical durability and anti-corrosion potential of oxide layers formed on oxide dispersion-strengthened (ODS) FeCrAl alloys in a liquid metal blanket environment



Institute of Science Tokyo

Exceptional corrosion resistance of ODS FeCrAl oxide dispersion-strengthened alloy in advanced liquid blanket environment for fusion reactors. 

image: 

Exceptional corrosion resistance of ODS FeCrAl oxide dispersion-strengthened alloy in advanced liquid blanket environment for fusion reactors.

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Credit: Masatoshi Kondo




Researchers explored protective coatings on advanced to resist corrosion in fusion reactors. They tested α-Al2O3 oxide layers on ODS alloys in a high-temperature, flowing lithium-lead environment. Even bare ODS alloys formed a durable γ-LiAlO2 layer in situ, which suppressed further corrosion. The layers exhibited strong adhesion under mechanical stress, making these findings crucial for improving material durability in fusion reactors and high-temperature energy systems.

Fusion reactors, a promising source of sustainable energy, require advanced materials that can withstand extreme temperatures and corrosive environments created by liquid metal coolants such as lithium and lithium-lead (LiPb) alloy. These coolants are essential in fusion reactors to extract heat and breed tritium, but their corrosive nature threatens the integrity of the structural materials used. LiPb is particularly aggressive, as it has a high concentration of lithium, which reacts with structural materials, causing corrosion and material degradation over time.

ODS FeCrAl alloys, known for their excellent high-temperature strength and corrosion resistance, have been proposed as promising candidates for fusion reactors and other high-temperature applications like concentrated solar power systems. These alloys rely on the formation of protective oxide layers, such as α-Al2O3, which offers stability and durability under high temperatures. However, in a liquid LiPb environment, the chemical interactions between the alloy and the coolant raise concerns about the stability and longevity of these protective layers.

In this view, a team of researchers from the Institute of Science Tokyo (Science Tokyo), led by Associate Professor Masatoshi Kondo in collaboration with Yokohama National University, Nippon Nuclear Fuel Development and Department of Research, National Institute for Fusion Science, conducted corrosion tests on oxide layers formed on ODS FeCrAl alloys under prolonged exposure to flowing liquid LiPb at elevated temperatures. Their study was published in the journal Corrosion Science on September 17, 2024.

The researchers carried out corrosion tests using two types of ODS FeCrAl alloys: SP10 and NF12. The tests were performed under both static and stirred-flow conditions at 873 K to simulate realistic scenarios in fusion reactor coolant systems. They employed advanced metallurgical analysis techniques, including scanning transmission electron microscopy coupled with electron energy loss spectroscopy, to investigate the composition and microstructure of the protective oxide layers formed on the alloy surfaces.

They found that the pre-formed α-Al2O3 layer effectively suppressed initial corrosion but partially transformed into α-/γ-LiAlO2 due to the adsorption of lithium. Interestingly, even without pre-oxidation, the ODS alloys in situ developed a durable γ-LiAlO2 layer, which served as a self-forming protective barrier. Microstructural analysis using advanced electron microscopy revealed the penetration of lithium into the α-Al2O3 layer, leading to the chemical transformation. Despite this, both α-Al2O3 and γ-LiAlO2 layers demonstrated strong resistance to exfoliation. Micro-scratch tests confirmed that these layers adhered strongly to the alloy surface, with minimal degradation, even under high thermal stresses caused by LiPb solidification.

“The lithium-aluminum oxide layer’s durability shows that these alloys could last longer in high-temperature, high-stress settings. This layer serves as a sustainable shield that continues protecting reactor components even after initial wear,” explains Kondo.

As nuclear technology evolves, these findings bring us one step closer to developing reactors that can run safely for extended duration, making sustainable energy sources more feasible. "Our findings show that ODS FeCrAl alloys, with their ability to form durable protective layers, could play a vital role in the future of fusion reactors and other high-temperature power systems,” says Kondo, highlighting the impact of the research study.


About Institute of Science Tokyo (Science Tokyo)

Institute of Science Tokyo (Science Tokyo) was established on October 1, 2024, following the merger between Tokyo Medical and Dental University (TMDU) and Tokyo Institute of Technology (Tokyo Tech), with the mission of “Advancing science and human wellbeing to create value for and with society.”

Exploring the corrosion resistance of ODS FeCrAl alloys and the role of protective α-Al₂O₃ and γ-LiAlO₂ layers in liquid LiPb environments


Corrosion test of ODS FeCrAl alloys in liquid LiPb at 873K (left and center) and STEM cross-sectional observation on the surface of pre-oxidized alloy after exposure to liquid LiPb flow (right)

Bridging the industry-university divide pays off for mission-driven institutions


New Catalyzing Collaboration report highlights US and Canadian success stories in an information age


 News Release 

Digital Science

Catalyzing Collaboration 

image: 

A new report published by Symplectic is a blueprint for leveraging universities’ research expertise and facilities to support industry needs.

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Credit: Symplectic / Digital Science




A new report lays out a blueprint for success for universities and industry partners alike, with a focus on leveraging universities’ research expertise and facilities to support industry needs.

The report – Catalyzing Collaboration: How Research Information Management Systems Drive Academic-Industry Partnerships – has been published today by Symplectic, a trusted provider of information management solutions.

Using case studies from the University of Toronto and the Ohio Innovation Exchange (OIEx), the report explores how advanced research information management systems can:

  • enhance the discoverability of research expertise and facilities
  • foster industry partnerships
  • drive meaningful collaborations both internally and externally
  • increase their positive impact on the economy and society.

The University of Toronto’s DiscoverResearch portal and the Ohio Innovation Exchange utilize Symplectic Elements to showcase their research expertise and assets. The report outlines how both platforms are successfully transforming the way industry partners engage with academic expertise.

In the report, Derek Newton, Assistant Vice-President, Innovation, Partnerships and Entrepreneurship at the University of Toronto, says: “Where companies have a challenge, they have a topic, their next step is: how do they identify the right people? That’s where DiscoverResearch comes in.

“DiscoverResearch is a really amazing new tool that helps industry navigate this very big institution – there are over 16,500 affiliated researchers, across multiple domains, and it allows a visitor to find all those types of researchers and to reach out.”

In the report, Jeff Agnoli, Senior Liaison, Corporate Partnerships, Ohio Innovation Exchange, speaks of the benefits for industry and local economies: “We leverage Elements’ ability to list affiliated faculty on each record so our industry partners can quickly identify potential collaborators’ profiles; recently we added a new category so that we can list certificate programs for employers interested in upskilling their workforce. This full catalog is incredibly impactful to current/potential industry partners, new faculty, as well as those we are trying to recruit.”

Digital Science’s Executive Vice President of Academic Markets, Jonathan Breeze, says: “Industry-university collaborations offer a huge range of benefits for both parties, including de-risking investment in future research. As highlighted by our latest report, the challenge of finding appropriate partners is also a shared problem and it’s great to see how Digital Science technology is helping form new connections that deliver real-world impact.”

The report contains details about:

  • industry-academic collaboration
  • the growing role of tech transfer
  • how to enable connection and collaboration
  • maximizing value from university assets and equipment
  • training researchers to meet industry standards and needs
  • the digital infrastructure underpinning success at the University of Toronto and the Ohio Innovation Exchange

The report concludes: “Looking to the future, the institutions that embrace these strategies will not only secure greater funding and partnership opportunities but will also create a lasting legacy of research impact, helping to foster economic growth, address global challenges, and support research excellence.”

 

Download a copy of the Catalyzing Collaboration report

 

About Symplectic

Symplectic works in pursuit of the advancement of knowledge, delivering flexible information management solutions that help universities, institutions and funders achieve their research goals.

Symplectic Elements is a highly configurable platform which ingests data from multiple sources to build a truly comprehensive picture of scholarly data and activities. With over 20 years’ experience and 130 clients, Symplectic Elements is trusted by universities, institutions and research organizations around the world.

About Digital Science

Digital Science is an AI-focused technology company providing innovative solutions to complex challenges faced by researchers, universities, funders, industry and publishers. We work in partnership to advance global research for the benefit of society. Through our brands – Altmetric, Dimensions, Figshare, IFI CLAIMS Patent Services, metaphacts, OntoChem, Overleaf, ReadCube, Scismic, Symplectic, and Writefull – we believe when we solve problems together, we drive progress for all. Visit www.digital-science.com and follow @digitalsci on X or on LinkedIn.

 

UC3M participates in a research project on biocomposites that transform key industrial sectors



Universidad Carlos III de Madrid




Universidad Carlos III de Madrid (UC3M) is participating in a European research project, called BIOntier, which is developing more sustainable materials than conventional ones, known as biocomposites, for industrial sectors such as the automotive, aeronautics, energy storage and water treatment industries.

“The materials we develop are not only more environmentally friendly, but also provide advanced technological solutions for the industries that use them,” explains Álvaro Vaz-Romero, head of the project at UC3M, a researcher in the Lightweight Structures Dynamics Group, which belongs to the University's Department of Continuum Mechanics and Structural Analysis. Their characteristics, lightness, recyclability, durability when receiving impacts or resisting high temperatures offer thermal, mechanical and chemical properties that position them as a sustainable alternative to conventional materials, according to the researchers.

Biocomposites developed by BIOntier cover applications as diverse as vehicle components, battery casings and dashboard panels, aeronautical structures and industrial equipment adapted to the thermal and mechanical demands of the industry. They are also used as structural impact absorbers designed to improve collision safety, low-pressure hydrogen storage tanks and high-pressure tanks designed to increase the durability of purification systems.

Towards a greener and more competitive industry

UC3M is participating in the project as leader of a work package focused on the experimental characterisation of these materials. This includes the design of tests to analyse the performance of the biocomposites under different loading conditions and working environments, as well as numerical simulation based on the data obtained in the tests. ‘Our laboratory performs part of these tests, combining experimental analysis and computational simulations to provide a complete picture of the behaviour of these materials,’ Alvaro explains.

All these experiments aim to improve both the synthesis and stability of biocomposites, while reducing their ecological footprint. ‘This is in line with the objectives of the circular bioeconomy, promoting sustainable materials that can compete in the global market, facilitating their integration into existing industrial products,’ concludes Álvaro.

The BIOntier project (Breaking Frontiers in sustainable and circular biocomposites with high performance for multi-sector applications), coordinated by the FORTH research centre in Greece and with funding of more than EUR 7 million (GA 101155925), brings together 25 partners including universities, research centres, SMEs and large companies from 12 countries. 

 

 

Emory-led Lancet review highlights racial disparities in sudden cardiac arrest and death among athletes



Emory Health Sciences




A recent major review of data published by the Lancet and led by Emory sports cardiologist Jonathan Kim, MD, shows that Black athletes are approximately five times more likely to experience sudden cardiac arrest (SCA) and sudden cardiac death (SCD) compared to White athletes, despite some evidence of a decline in rates of SCD overall. SCA and SCD have historically been a leading cause of mortality among athletes, particularly those involved in high-intensity sports.

The disparities in SCA/D rates highlights the need for increased research into the social determinants of health in younger athletes, a topic that remains understudied, according to Kim.

After examining a repository of national and international data focused on SCA/D in athletes accumulated over the last 30 years, Kim and colleagues from Lausanne University Hospital, Morristown Medical, Massachusetts General Hospital, and other prominent institutions reviewed the significant racial disparities that also persist in athlete electrocardiography (ECG) screenings, which have become a standard practice for competitive athletes.

These screenings often yield more false positives in Black athletes, which means that athletes may be wrongly identified as having a serious heart condition. For those with limited access to comprehensive follow-up testing this is especially problematic as these individuals may face unnecessary stress and may not be able to receive follow-up care to confirm whether results are accurate.

Social determinants of health, such as economic stability, proximity to health care facilities, access to health information, and experiences with discrimination can play a significant role in disparities in health outcomes, even in young athletes. By incorporating social determinants of health into future research, Kim says we may be better poised to understand how to mitigate the impacts on young athletes in particular.

“To truly address these disparities, it’s not enough to just screen for potential problems,” Kim says. “There needs to be an understanding on how to tackle the underlying social determinants of health that puts these athletes at a greater risk.”

In the Lancet review, Kim and colleagues stress that proper management of sudden cardiac arrest in athletes starts with adequate pre-participation evaluation (PPE) which involves careful planning and sufficient resources. “We need to look for potential underlying health conditions. We also need to consider all the environmental stressors that young individuals have to deal with and also where they grow up,” says Kim. An effective PPE history and physical examination should include appropriate follow-up, especially if ECG is included and abnormalities detected.

Looking ahead, the growing focus on this topic marks a substantial shift. “Just five to ten years ago, I doubt many were thinking about social determinants of health and impacts on young athletes,” says Kim. Asking these critical questions is a major step in the right direction. moving forward its essential to continue raising these questions but also taking action to address them.