Sunday, May 31, 2026

 

Rwenzori Mountains’ first major fire in 12,000 years marked new era for climate



Penn State researcher who contributed to findings says effects of blaze continue to threaten rare pristine alpine environment



Penn State

Students return from collecting a core sample in a lake in Uganda's Rwenzori Mountains. 

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Doctoral student Caleb Norville of Penn State and Meredith Parish of George Mason University return from collecting a core sample in a lake in Uganda's Rwenzori Mountains. 

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Credit: Courtesy Penn State





UNIVERSITY PARK, Pa. — For the past several years, Penn State geoscientist Sarah Ivory and her students have been among a team of scientists scaling the East African Rwenzori Mountains, collecting sediment core samples from lakes formed at the end of the last ice age as glaciers began receding in the region some 12,000 years ago.

Among those cores was a surprising revelation: A 2012 wildfire that ravaged 16 square miles of the forest and alpine landscapes at more than 13,000 feet above sea level was unprecedented in at least the last 12,000 years. The researchers also found evidence in fossilized pollen that the fire significantly shifted the region’s ecology. Led by Andrea Mason, a doctoral candidate at Brown University, the team recently published these findings in the journal Nature.

The blaze in the alpine moorland surprised forest experts who assumed the climate was too cold and too wet for fires to start and to spread, Ivory said.

Within the cores, researchers looked at the remnants of charcoal to piece together the fire history of the area since the lakes originated. The cores show no fire activity for about 10,000 years. A slight increase in fire activity about 2,000 years ago — coinciding with an increase in human activity in the region — was recorded in a lower elevation lake. In 2012, the amount of charcoal in the cores shot up more than 100 times, aligning with the timing of the blaze at the border of Uganda and the Democratic Republic of Congo, at higher elevation. Researchers also assessed historic pollen records to determine there were dramatic shifts in the region’s ecology over the past 2,000 years as fire increased.

“The fact that this one fire in 2012 is the only fire that’s happened on this mountain for the entire existence of the lake is mind blowing,” Ivory said. “It’s like the image of a plastic bag in the Mariana Trench. We shouldn’t see human influence in an area that’s this remote, but it’s there.”

The team trekked the mountainside over a period of nearly two weeks, collecting sediment cores from two lakes: Lake Mahoma at about 9,000 feet and Lake Kopello in the alpine zone around 13,000 feet. Lake runoff and wind concentrated indicators into the soft underwater beds captured in the cores that tell us about past plants and climates on the mountain like pollen grains, leaf waxes, fossil bacteria and other biomarkers.

One goal of the project, Ivory said, was to help understand rapid changes to the low-lying village more than 10,000 feet below the Ugandan peaks. The Rwenzori Mountains National Park, a UNESCO World Heritage Site in Uganda, is home to the last remaining glacier that numbered in the dozens roughly 100 years ago. In that time, the region has lost more than 90% of its glacial ice.

In the village of Kilembe, deadly floods, landslides and mudslides have ravaged infrastructure, homes, farmland and livestock in recent years. In her research at large in Africa and parts of the Middle East, Ivory is assessing how warming since the last ice age has and continues to affect ecosystems. She and her students have been assisting with reforestation and forest mapping to combat the effects of climate change in the area.

The fire in the alpine region is another sign of change, Ivory said. Kilembe experienced massive flooding the year following the fire — which burned 18% of the catchment above the village. The unpredictability of the river that runs through the village continues to plague the community, Ivory said, with continued flooding that permanently knocked out power years ago.

“Whenever it rains, everything is disrupted,” Ivory said. “Flooding destroyed bridges and forced boulders into the river, making it difficult to rebuild what was there. It’s really transformed a community just downstream from the 2012 fire.”

Another key finding, Ivory said, was told through the pollen records analyzed at Penn State. The pollen revealed massive changes associated with early human fires as well as more recent fires driven by human-induced climate change to the ecology of the Rwenzori Mountains, one of the most unique and biodiverse mountainous regions on the planet. Much like isolated areas such as the Galapagos Islands offer a glimpse of evolutionary changes, this remote area of Uganda is a hot spot for ecological research and discovery, Ivory said.

The Rwenzori Mountains belong to a network of Afroalpine “sky islands,” isolated, high-altitude environments that support unique plant and animal life found nowhere else on Earth. Comparable systems, such as Mount Kilimanjaro and Mount Kenya, have also seen recent wildfire activity, suggesting that rising temperatures may be altering ecosystems that were once naturally safeguarded by extreme alpine conditions.

Pollen records showed extensive changes in plant life, beginning around 2,000 years ago. This period coincides with an increase in human intervention and agricultural practices. At lower elevation, pollen associated with rainforest trees declined after the period when fires were detected, while pollen associated with bamboo and other grasses increased.

Since 2012, Ivory said, the slow growing mountainside trees have remained damaged and the forest is at risk of ecosystem transformation, especially if fires continue to persist.

“The Rwenzori Mountains have one of the most diverse and pristine expressions of this type of vegetation,” Ivory said. “Similar areas have a lot more disturbance and a lot more fire. Until recently, this was a holdout; it was one of the best examples of this special ecosystem and now that’s under threat.”

In addition to Ivory and Mason, co-authors include Meredith Kelly, Dartmouth College; Bob Nakileza, Makerere University; Eleanor Pereboom and James Russell, Brown University; and Richard Vachula, Auburn University.

 

Common protective soybean seed treatment may not increase profitability



Penn State





UNIVERSITY PARK, Pa. — Many soybean farmers use seeds treated with fungicides to ward off disease, but the profits from these increased yields might not offset the cost of the treatment in most cases, according to a study published in Scientific Reports by researchers at Penn State.

The researchers analyzed how seed treatments affect yield and profitability in soybean farms in the Midwest and found that yield gains were modest and often did not offset the added cost of the treatment. Additionally, financial benefit was likely only when seed treatment costs were low and soybean prices were high.

Paul Esker, professor of epidemiology and of field crop pathology in the College of Agricultural Sciences and lead author on the study, said the findings suggest that growers may want to carefully evaluate the use of fungicide seed treatments on their farms.

“Farmers often talk about putting money in their pockets, and our research suggests that this can occur by reducing input costs rather than by assuming an economic gain from using treated seeds,” said Esker, who is also affiliated with the Plant Institute in the Huck Institutes of the Life Sciences. “Growers may want to use treated seeds only in specific, high-risk situations or after verifying a positive return-on-investment.”

The use of fungicide-treated seeds has risen sharply in the last few decades, the researchers said. While about 8% of soybean seeds were treated with fungicide in 1996, that figure rose to 60% to 75% by 2015.

Despite their popularity, Esker said their use may not result in higher profits for farmers. Additionally, he noted, unnecessary use of fungicides could result in potentially harmful effects on beneficial microbes in the seeds and soil.

“Adoption of seed treatments has continued to increase in U.S. soybean production systems, but uncertainty remains about whether their use is necessary,” Esker said. “Furthermore, given the parallel questions about the use of seed-treatment insecticides, we recognized that addressing them could go a long way toward helping farmers make better soybean management decisions.”

For the study, the researchers analyzed data from both randomized controlled trials and large-scale, on-farm observational studies previously conducted by other teams.

Data from RCTs was limited to studies in the U.S. Midwest that included crop data from both treated seeds and untreated control seeds. Observational data included self-reported information from growers across three growing seasons from 2014 to 2016 and 10 Midwest states.

“This approach moves us away from a purely correlative interpretation of the results and aligns more closely with the questions that farmers often ask us,” Esker said.

Analysis of data from randomized controlled trials found an average yield increase of 22.2 kilograms per hectare (kg/ha) — or about 19.81 pounds per acre — that could be attributed to fungicide seed treatments. Analysis of observational data found a similarly small average yield gain of approximately 36 kg/ha, or about or about 32.12 lbs/acre.

Additional simulations showed that these gains in crop yields often didn’t offset the costs of seed treatment.

“Our results add to a growing body of evidence that fungicide seed treatments do not provide consistent, reliable protection against downside yield loss risk,” Esker said. “They also will help us collaborate with farmers to determine under what conditions a fungicide seed treatment may be beneficial.”

The findings also raise concerns, the researchers said, about the widespread use of fungicide seed treatments on the microbiomes of seeds and their surrounding soil. Seeds and soils have unique compositions of microbes that benefit germination and seedling development, which could be disrupted by unnecessary fungicide use.

“Given the small economic benefits and these known ecological risks, policymakers may want to prioritize support for research and extension programs that help growers identify the specific conditions where seed treatments are likely to be profitable,” Esker said.

In the future, the researchers said the development of tools to assess specific fields’ pathogen risk may be a more sustainable and economical approach than the current widespread use of preventative fungicides.

Denis A. Shah, Kansas State University; Spyridon Mourtzinis, Tatiane Severo Silva and Shawn P. Conley, University of Wisconsin-Madison; and Patricio Grassini, University of Nebraska-Lincoln, also co-authored the study.

The U.S. Department of Agriculture National Institute of Food and Agriculture, Wisconsin Soybean Marketing Board, North Central Soybean Research Program, and the United Soybean Board helped support this research.

 

FAPESP seeks to boost scientific collaboration between São Paulo and the United Kingdom


The Foundation is promoting the FAPESP Week symposium in England for the third time, with the aim of consolidating and expanding partnerships in strategic areas such as energy transition and artificial intelligence



Fundação de Amparo à Pesquisa do Estado de São Paulo





From June 2 to 4, the Science Museum in London will exhibit a sample of scientific production developed in the state of São Paulo and the United Kingdom in areas such as artificial intelligence, energy transition, and health. The century-old museum, founded in 1857, will host FAPESP Week London.

Organized in cooperation with the Science Museum, UK Research and Innovation (UKRI), the Royal Society, the British Academy, and the UK Science and Technology Network (STN) in Brazil, with the support of the Brazilian Embassy in London, the event aims to consolidate and expand scientific partnerships in strategic areas of mutual interest between researchers from São Paulo and the UK.

This will be the third time that FAPESP will hold the symposium in England – with previous editions in 2013 and 2019 – reinforcing the role of the United Kingdom as the second main scientific partner of the state of São Paulo in terms of shared research production on the global stage, behind only the United States.

“Holding this third edition in the United Kingdom attests to the capacity for joint scientific production between the region and the state of São Paulo,” Raul Machado, manager of institutional relations at FAPESP, tells Agência FAPESP.

The academic sessions will bring together scientists from both countries to discuss advanced research results and identify new opportunities for joint funding. The debates are aligned with FAPESP’s strategic funding axes and will cover topics such as energy transition; health, health data, and precision medicine; artificial intelligence and data for society; biodiversity, bioeconomy and circular economy; sustainable use of resources; and museums, heritage, and society.

One of the main highlights of this edition is the inclusion of a debate on the relevance of science museums in disseminating knowledge, connecting the vocation of the British institution to the São Paulo experience. The program will include the participation of the Butantan Institute, which will take a joint exhibition project to England.

“Including museums was an intentional choice to give space to this type of dissemination. We’re bringing the Butantan, which is an institution associated with intense technological development activity,” explains Machado. In addition, artificial intelligence (AI) will act as a cross-cutting theme throughout the program. “AI is permeating everything from health to technological innovation; these are the keywords of the meeting.”

The Brazilian delegation will also follow a parallel agenda of visits to cutting-edge innovation environments in the British ecosystem, including the Data Science Institute – the data science and AI hub of the London School of Economics (LSE), Genomics England – a UK government company created in 2013 with the goal of integrating genomic medicine into the British public health system (NHS), and the Cell and Gene Therapy Catapult – a non-profit center of excellence established by the British government with the mission of accelerating the development and manufacture of cell and gene therapies.

Five deep-tech companies (science and technology-based startups) supported by the Innovative Research in Small Businesses Program (PIPE) will participate in the event's discussion sessions, in their respective areas of expertise. These are: SleepUp, Inovia, Fubá Educação Ambiental, @Tech, and Ciclou.

Increased Collaboration

Now in its 27th edition, the FAPESP Week symposium series, organized since 2011, has created opportunities and facilitated cooperation, consolidating and expanding partnerships between researchers from the state of São Paulo and colleagues from around the world.

More than bringing researchers closer institutionally, the practical effect of FAPESP Weeks is evidenced by the significant growth in the volume of collaborative research after the meetings, emphasizes Machado.

After the event in Germany in March 2025, for example, the number of collaborative research proposals submitted to FAPESP jumped from 294 to 582, representing an increase of almost 98%. A similar scenario was observed in Spain, where an edition of the meeting was held in November 2024 and proposals increased from 283 to 471 (a rise of 66.4%), and in France, which hosted the event in June 2025 and recorded 51.3% growth, going from 374 to 566 submitted projects.

Even in smaller scientific communities, such as in Uruguay, where the event took place in November 2025, the symposium’s stimulus proved robust, causing submissions to jump from 18 to 51 proposals. These numbers consolidate FAPESP’s strategy of focusing on in-person forums to transform institutional dialogue into real and measurable scientific cooperation, Machado notes.

“International partners, in theory, are already regular collaborators. But when you hold an in-person and focused event of this size, attention turns entirely to cooperation, and that triggers a surge in the number of research proposals,” the manager explains.

The organizers expect FAPESP Week London to replicate this historic success, turning the three days of debates into a new wave of joint projects funded by FAPESP and its partners, thereby boosting the internationalization of science produced in the state of São Paulo.

 

Finding new ways to measure the local sustainability of rural tourism




Penn State





UNIVERSITY PARK, Pa. — Tourism affects local populations differently in counties across the U.S., but measuring these effects may now be easier thanks to a new tool developed as part of a study by researchers at Penn State and West Virginia University Extension.

For the study, published in the journal Tourism Economics, the researchers developed a sustainability index to assess how tourism affects counties according to a number of factors that measure the areas’ economic, social and environmental well-being. They found that counties relying heavily on tourism varied widely in their ability to keep it from overwhelming local resources, with no destination performing well on every dimension.

Critically, the researchers said, the index allowed them to measure counties’ sustainability as it changed over a period of 10 years instead of at one point in time.

Luyi Han, assistant professor in regional and agricultural economics in the College of Agricultural Sciences and lead author on the study, said the findings give new clues about how tourist areas can boost their well-being.

“Sustainability shouldn’t be treated as a branding exercise alone: investments in housing, public safety, environmental protection and community well-being may also strengthen a destination’s long-term economic resilience,” Han said. “More broadly, the findings show that there is no one-size-fits-all model of sustainable tourism. Local conditions matter, and effective strategies need to be tailored to the specific strengths and vulnerabilities of each community.”

Stephan Goetz, professor of agricultural and regional economics and co-author on the paper, added that as more rural communities seek to expand their local tourism and recreational sectors as a source of economic and community development, long run sustainability becomes more important.

“For example, local residents ideally will also benefit from tourist dollars, and any recreational activity should not come at the expense of the natural environment when that is what attracts tourists in the first place” said Goetz, who is also the director of the Northeast Regional Center for Rural Development. “This indicator is designed to help address these concerns.”

The research was inspired by a growing tension in tourism-dependent communities, according to the team. While tourism can be an engine of economic growth, it can also create pressures on housing, community well-being and the environment.

“In the United States, these questions are especially important because there has been no consistent, longitudinal way to measure whether tourism development is actually sustainable across places and over time,” Han said. “Much of the existing work relies on local surveys or case studies, which can provide valuable insights but are costly, difficult to repeat and hard to compare across destinations.”

The researchers said they wanted to respond to that gap by asking whether tourism sustainability can be tracked in a more systematic, scalable and comparable way.

For the study, the researchers used existing data — such as the US Census data, environmental monitoring data, crime statistics and health measures — to build a novel composite sustainable tourism index.

The index uses six measures to represent the economic, social and environmental well-being of tourism counties: the percentage of income a household spends on housing, poverty rates, violent crime rates, life expectancy, the amount of pollution in the air and pollution sites.

After calculating the change in each measure between 2009 and 2019, the researchers found that on average, poverty rates fell and air quality improved over the study period, suggesting some positive economic and environmental gains.

At the same time, housing affordability remained a major concern and pollution increased in many places. Finally, a sharp rise in violent crime was found across many recreation-dependent counties.

Additionally, the researchers found strong geographic variation, with many higher-performing counties concentrated in the Mountain West, Pacific Northwest and Alaska, though even these places often faced significant affordability pressures.

Finally, the researchers also found patterns linked to the COVID-19 pandemic.

“Counties with stronger sustainability performance before the pandemic tended to experience smaller employment losses in the tourism sector and stronger recovery afterward, suggesting that sustainability may also contribute to resilience during major shocks,” Han said.

The findings point to several potential policy implications, according to the researchers. For example, concerns about housing affordability could be addressed with interventions such as inclusionary zoning or tourism tax revenues dedicated to affordable housing development, while increases in violent crime may require safety strategies that address the unique challenges of tourism communities.

The researchers said that in addition to gaining insights about how tourism affects counties over time, the tool they developed can also be used to aid in decision-making.

“For destination managers and local governments, the index offers a way to establish a sustainability baseline, compare performance with similar destinations, and track change over time,” Han said. “It can help identify where tourism is creating uneven outcomes — for example, where economic gains may be accompanied by rising housing pressures or worsening social conditions — and support more targeted policy responses.”

In the future, additional studies could examine exactly how tourism impacts different dimensions of local communities — as well as why some towns achieve more balanced outcomes than others, the researchers said.

Daniel Eades and Doug Arbogast, both from West Virginia University, also co-authored this study.

The U.S. Department of Agriculture's National Institute of Food and Agriculture helped support this research.

 

Stopping ticks in their tracks


UT researchers discover protein that may block disease transmission


University of Tennessee Institute of Agriculture

UT College of Veterinary Medicine Professor professor Hameeda Sultana 

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Research led by University of Tennessee College of Veterinary Medicine Professor Hameeda Sultana and alumni postdoctoral fellow Waqas Ahmed has identified a tick protein that could help block disease transmission before it fully happens.

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Credit: Photo by S. Bridges, courtesy the University of Tennessee.






Few creatures inspire as much universal dislike as ticks. Though small, these parasites have an enormous impact on human and animal health. Each year, ticks spread viruses and bacteria that infect people, livestock, wildlife and pets around the world. Scientists at the University of Tennessee College of Veterinary Medicine are working to better understand how ticks transmit these diseases—and how to stop them.

In a new study published in The EMBO Journal, researchers identified a tick protein that could help block disease transmission before it fully happens. The EMBO Journal, published by the European Molecular Biology Organization, is one of the world’s leading journals in molecular biology.

The research was led by professor Hameeda Sultana and alumni postdoctoral fellow Waqas Ahmed, and contributors included former graduate students Wenshuo Zhou and Kehinde Fasae, current graduate student Md Bayzid, and faculty collaborators professor Girish Neelakanta and former UT clinical assistant professor Denae LoBato. Supported by funding from the National Institutes of Health, the work highlights the UT Institute of Agriculture’s role in advancing research on vector-borne diseases.

Between 2018 and 2020, Sultana’s laboratory was the first to identify exosomes derived from tick saliva and salivary glands and from tick and mosquito cells. In this groundbreaking work, the UT research team discovered that ticks produce an exosomal glycine-rich protein that plays a vital role in helping ticks feed and transmit viruses. “Exosomes are tiny bubble-like vesicles with messages in them,” explains Sultana. “They are tiny membrane-bound particles that transport proteins and other biological signals between cells and tissues. “When a tick bites its host, the interaction is more complex than it may appear. Tick saliva contains exosomes filled with a sophisticated cocktail of molecules, allowing them to feed undetected while avoiding triggering the host’s immune defenses. These vesicles carry a variety of tick proteins that may help pathogens move between ticks and hosts. “They contain several arthropod proteins that could facilitate tick feeding, pathogen acquisition from infected hosts to naïve ticks, and transmission of pathogens from infected ticks to naïve hosts,” Sultana says.

When the researchers used genetic tools to silence the gene responsible for this protein, the effects were dramatic. Ticks lacking the protein struggled to feed effectively and showed reduced body weight after feeding. Even more importantly, virus levels were significantly lower. The findings build on years of work exploring how ticks use microscopic vesicles to interact with their hosts.

This protein could be used in a vaccine approach. Faculty collaborator Girish Neelakanta says discoveries like this highlight how understanding tick biology can reveal new opportunities to prevent disease transmission. “Ticks transmit several pathogens,” Neelakanta explains. “Studies like this provide evidence about tick molecules that play an important role not only in tick biology but also in the interactions with pathogens.”

Researchers believe exosomes could become an important target for disease prevention strategies. “Since the identification of exosomes from ticks from my laboratory, several studies—including our own—have emphasized the importance of these vesicles in tick feeding and interactions with pathogens,” Sultana says. “This is an exciting area of research that could open several avenues for the development of arthropod exosome-based strategies to target vector-borne diseases.”

According to Neelakanta, targeting these molecules may offer a new way to interrupt the transmission cycle. “Targeting this type of protein might be an ideal approach to affect transmission of several pathogens from ticks.” This type of approach is known as a transmission-blocking vaccine. Rather than targeting the virus itself, the vaccine targets a molecule in the tick, preventing the tick from successfully feeding or transmitting pathogens. By interrupting this process early, scientists hope to stop infections before they ever reach the host.

As tick-borne diseases continue to increase worldwide, the need for new prevention strategies is becoming more urgent. Current control methods rely on avoiding tick bites or reducing tick populations. However, researchers are increasingly investigating ways to interfere with the biological mechanisms that ticks rely on to feed and transmit disease.

The discovery of this exosomal protein adds to a growing body of research exploring how parasites communicate with their hosts at the microscopic level. Scientists are still in the early stages of understanding the role exosomes and other extracellular vesicles play in these complex interactions.

Findings like these demonstrate how fundamental molecular biology research can lead to practical advances in both animal and human health. By uncovering the hidden mechanisms ticks use to spread disease, scientists are opening the door to innovative new strategies for prevention.

Sometimes the best way to stop a parasite is to understand it at its smallest scale. In this case, the key to combatting ticks may lie within microscopic packages only billionths of a meter wide. One day, these tiny messengers could help prevent the spread of vector-borne diseases.

One of 33 veterinary colleges in the United States, the UT College of Veterinary Medicine educates students in the art and science of veterinary medicine and related biomedical sciences, promotes scientific research and enhances human and animal well-being.

The University of Tennessee Institute of Agriculture is comprised of the Herbert College of Agriculture, UT College of Veterinary Medicine, UT AgResearch and UT Extension. Through its land-grant mission of teaching, research and outreach, the Institute touches lives and provides Real. Life. Solutions. to Tennesseans and beyond. utia.tennessee.edu.