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Monday, October 05, 2026

The Illusion Of Hard Power: Reflection On How Democratized Technology And Strategic Geography Broke The Superpower Monopoly On War



A former infantry officer argues that Vietnam, Iraq, and African interventions show firepower does not buy compliance when a population treats the fight as existential, and that external backing or neglect left long instability from Congo and Somalia to Libya and the Sahel.

The 2026 Iran war and Ukraine are presented as a cost inversion: cheap mass drones and missiles force million-dollar interceptors, and Hormuz pressure moved the contest into shipping, insurance, and energy; Ukraine’s sea drones against the Black Sea Fleet are cited as the same pattern.

The conclusion is that total destruction is politically and strategically unavailable, so China’s caution on Taiwan and future stability depend on defensive sustainability and compromise rather than regime change—an argument, not a demonstrated law.



Written from the unique perspective of a former infantry officer of the late sixties, this paper examines the paradigm shift in 21st-century geopolitics, in which conventional military dominance no longer guarantees political control. Tracing an evolutionary line from the ideological endurance of Vietnam to the urban insurgencies of Iraq, the paper argues that contemporary conflicts involving Iran and Ukraine mark a watershed in modern warfare. By pairing fierce nationalist resolve with cheap, mass-produced asymmetric technology, weaker states have triggered a severe industrial-economic inversion, bankrupting expensive Western defensive systems through supply-chain attrition. Crucially, the paper highlights how Iran successfully weaponized its strategic geography—specifically the Strait of Hormuz—shifting the center of military gravity into global shipping, insurance, and energy networks and holding global markets hostage. Confronted with the reality that victory against an existential defense would require total destruction, superpowers such as the United States, Russia, and an island-facing China are hitting a structural wall. The paper concludes that absolute military coercion is obsolete; future global stability depends on balancing defensive sustainability with soft power, diplomatic tolerance, and mutual compromise.

The Illusion of Hard Power

In 1967, I was a young officer training at the Advanced Infantry School at Fort Benning, Georgia, alongside American officers. The ghost of the Vietnam War hung heavy over every field exercise, tactical briefing, and grueling march we endured. We were trained by men who had just returned from those jungles, and the lesson they drilled into us had nothing to do with a lack of American firepower. Instead, they forced us to confront the limits of willpower. We learned the hard way that you cannot militarily break an indigenous population when they are fighting for their own dirt. Fifty years have passed since my time in uniform, and as I get older, I watch the news and realize that our strategic leaders are still trapped in the same fallacy. We continue to assume that an overwhelming accumulation of military might can force a weaker nation to surrender its independence and existence. History has shattered that illusion across my lifetime, from Southeast Asia to the deserts of Iraq, and now to the tech-driven battlefields of Ukraine, the proxy conflicts of Africa, and the waters of the Persian Gulf. The basic reality of modern conflict is that military dominance no longer equals political control. When a nation views a conflict as existential, hard power can only achieve two things: death and destruction. It cannot buy compliance. Today, because the means of resistance have been cheapened and widely democratized, the pursuit of absolute control is a path toward mutual ruin. True strength for the future lies not in our capacity to destroy, but in our willingness to tolerate, compromise, and engage the world through mutual respect.

To understand why US military dominance is broken, we must look closely at how resistance has changed since my time. In the 1960s and 70s, US conventional doctrine was pushed to its limits. The United States dropped millions of tons of ordnance on Vietnam yet failed to achieve its political objectives. The failure was not a lack of tactical skill on the ground; it was a fundamental strategic failure to recognize that a population defending its homeland measures victory purely by its willingness to keep dying. Against deeply rooted nationalism, conventional bombing campaigns could not break the enemy’s resolve. As my generation learned through immense trauma, a democracy simply cannot sustain a war of indefinite casualties for non-existential goals. Decades later, I watched the next generation of American soldiers march into Iraq. While the initial conventional phase of that war was won in a matter of weeks through “Shock and Awe,” the secondary phase of controlling and governing the country was completely lost. Our political leaders were blindsided by the raw willpower of a population that flatly rejected a foreign occupation. The battlefield quickly evolved into a decentralized, borderless insurgency fueled by improvised explosive devices and urban terror. Iraq demonstrated what any seasoned infantryman fears in his bones: demolishing a state’s conventional armor and infantry is the easy part. Holding and controlling a hostile nation is politically, morally, and economically unsustainable. The sheer friction of trying to enforce compliance against an unwilling population eventually drains a superpower’s resources and erodes its domestic political capital.


Yet this failure to understand the limits of hard power is not confined to the Middle East or Southeast Asia. When evaluated against my twenty-eight years as a UN peacemaking consultant across Africa’s most volatile war zones, the limits of conventional military coercion become even more starkly apparent. In all the wars I have witnessed on the African continent, there was always a degree of heavy-handed, unbalanced, or indifferent Western and global involvement that excluded local populations and created a legacy of perpetual instability. Cold War logic led to American support for the dictator Mobutu Sese Seko in the Democratic Republic of Congo. For Washington, this was a low-cost transactional alignment; for the DRC, it left behind a legacy of systemic fracture and a perpetual war that refuses to heal. Similarly, American indifference during the Rwandan genocide left a scar on America’s declared role as an advocate for genocide and crimes against humanity, and its unwise, heavy-handed intervention followed by a disgraceful exit in Somalia fundamentally altered the regional landscape, leaving Somalia trapped in a cycle of warlordism from which it cannot recover. In Libya, a relatively low-cost NATO aerial intervention to overthrow Gaddafi resulted in a fractured state that became a breeding ground for human trafficking, weapon proliferation, and militia warfare that spilled across the Sahel. Historical alignments like the American-supported Charles Taylor created havoc and civil war across both Liberia and Sierra Leone, proving that short-sighted external backing yields catastrophic regional consequences on the back end.


Today, this cycle continues as global superpowers and regional actors treat the continent as a theater for cheap geopolitical disruption. In Central and West Africa, Russia uses its mercenary arm, formerly Wagner and now Africa Corps, as a low-cost tool to loot mineral resources and displace Western influence. Meanwhile, in the Horn of Africa, the absence of a clear, balanced US policy has allowed its allies, the UAE and Saudi Arabia, to wage destructive proxy wars to secure their strategic and mineral interests. This echoes the historic “Françafrique” policies of control in West and Central Africa, where foreign dictation systematically excludes local people from the economic value chain. When war is supported, sponsored, or neglected by global powers, it becomes a negative-sum game where everyone loses. Because of these heavy-handed or neglectful policies, Africa’s true potential is suppressed, making it impossible to establish equitable, win-win trade or security architectures. Instead of being a robust global partner, these destabilized regions are forced into a state where they become involuntary exporters of instability through migration crises, piracy, and transnational terrorism. The West is then forced to spend trillions on reactive border security and counter-terrorism operations—a massive, unsustainable defense expenditure triggered by the long-tail consequences of original policy failures. Africa is left unable to heal itself, the West remains trapped in a cycle of reactive containment, and the global rules-based order faces an asymmetric threat to peace that cannot be solved by expensive weapons alone.


This structural failure of global foreign policy mirrors the tactical crisis we see on the modern battlefield, driven by the brutal mathematics of the Cost-Imbalance Doctrine. Modern warfare is no longer dictated by platform sophistication but by logistics, replacement speed, and lopsided economic exchange ratios. The collapse in the cost of commercial electronics, additive manufacturing, and open-source autonomous systems has shattered the traditional cost curve, tilting the strategic advantage sharply toward mass-produced, low-cost offense. The 2026 war involving Iran represents the ultimate, terrifying evolution of this trajectory, presenting a style of warfare that my peers in the seventies could scarcely have imagined. If Vietnam required dense jungles and Iraq required complex urban networks, modern asymmetric warfare requires only three things: basic, a determined population, universally manufacturable technology, and the strategic weaponization of geography. Iran effectively rewrote the global rules of engagement by manufacturing mass-produced, low-cost weapons—primarily twenty-thousand-dollar kamikaze drones and standard ballistic missiles. This has created a catastrophic economic and industrial imbalance for Western forces. Today, advanced militaries are forced to defend multi-billion-dollar assets like aircraft carriers by firing two-million-dollar air-defense interceptors at targets that cost less than a used car. When a five-hundred-dollar FPV drone or a thirty-thousand-dollar Shahed loitering munition forces a defender to fire a multi-million-dollar Patriot, THAAD, or SM-3 interceptor, the exchange ratio becomes unsustainable. This is no longer a war of tactical maneuver; it is a war of supply chain attrition, and the mathematics favor the cheap.


Furthermore, Iran’s true stroke of strategic genius was recognizing that its geographic position is a more powerful weapon than any nuclear arsenal. By sitting directly astride the Strait of Hormuz—the narrow maritime bottleneck through which twenty percent of the world’s petroleum flows—Iran shifted the center of military gravity entirely out of the mud and into global financial markets. By deploying its low-cost sea-denial arsenal to menace commercial shipping, it effectively nationalized a global commons. This strategy weaponized marine insurance networks, sent global energy prices soaring, and proved that controlling a geographic bottleneck allows a weaker state to hold the entire global economic system hostage. This is why Iran marks a watershed moment: it demonstrated that geography, activated by cheap tech, can completely bypass a superpower’s military superiority to strike directly at its domestic and economic vulnerabilities. We see proof that this shift is a universal law, not an American exception, in the stagnation of the Russian war machine in Ukraine. When Russia launched its full-scale invasion, conventional military wisdom predicted a rapid collapse of the Ukrainian state within days. Instead, the world witnessed the brutal stagnation of a traditional military giant. Ukraine countered massive armored columns and superior air power by leveraging the same formula: boundless national will paired with asymmetric technology. Armed with relatively inexpensive, mass-produced anti-tank missiles, first-person-view kamikaze drones, and decentralized digital command networks, Ukraine transformed the battlefield into a meat grinder for conventional assets. Ukraine’s ability to completely neutralize Russia’s Black Sea Fleet—not with a rival navy, but with low-cost, domestically manufactured explosive sea drones—perfectly mirrors how the vulnerability of multi-billion-dollar warships has been exposed globally.


This new reality explains the profound caution we see in East Asia regarding the Taiwan Strait. Objectively, China possesses the overwhelming conventional means—the world’s largest navy, advanced missile arsenals, and proximity—to launch an invasion of Taiwan. Yet Beijing hesitates. This caution stems from a clear-eyed analysis of these new rules of engagement. The Chinese leadership understands that invading Taiwan would mean wading directly into an asymmetric trap. Taiwan has spent decades preparing a “porcupine strategy” centered on cost-imbalance warfare. Crossing a hundred miles of open sea leaves Chinese transport ships highly vulnerable to swarms of low-cost, domestically produced anti-ship missiles and autonomous sea drones. Even if Chinese forces landed successfully, controlling a highly urbanized island of twenty-three million people against a deeply nationalist insurgency would mirror our catastrophic occupation failures in Iraq, multiplied tenfold, while inflicting an estimated two-and-a-half-trillion-dollar hit on the global economy. China’s hesitation proves the thesis: they recognize that while they have the hard power to cause immense death and destruction, they cannot guarantee surrender or control.

When a superpower faces a determined populace armed with universally manufacturable denial weapons and backed by strategic geography, it hits a wall. Because economic sanctions and localized strikes fail to break a deeply nationalist population, a superpower is left with only one military option to force an unconditional win: total destruction. Forcing a sovereign nation to abandon its existential interest today would require sustained, uninhibited bombardment or the use of nuclear weapons. However, as any strategist knows, this is a dead end. If the resisting nation or its allies possess even primitive nuclear or chemical deterrents, any escalation toward total destruction guarantees mutually assured destruction(MAD). Furthermore, neither the domestic population of a democracy nor the international community will tolerate the absolute annihilation of a country. Because total destruction is morally, politically, and strategically impossible, unconditional surrender is a relic of the past. Hard power has reached its absolute limit. If the accumulation of military might can no longer buy security or compliance, the global architecture must undergo a pragmatic revolution. This is not an appeal to utopian idealism; it is hardheaded realism from someone who has spent a lifetime reflecting on the cost of war. When conflict becomes too expensive for the strong and resistance too cheap for the weak, coexistence is the only affordable strategy left on the table.

Conclusion

True national security must be built on a balanced matrix of defensive sustainability and soft power. Superpowers must pivot away from a doctrine of regime change, containment, and forced compliance and toward policies of tolerance, compromise, and mutual respect. If a powerful nation needs resources, stable trade routes, or geopolitical cooperation, it can no longer acquire them bythe barrel of a gun or the threat of a carrier strike group. It must acquire them through diplomatic reciprocity. By recognizing the sovereignty and existential interests of smaller nations, superpowers can foster partnerships built on mutual benefit rather than perpetual, exhausting hostility. The lessons of my lifetime are clear. The world will never know peace, and superpowers will never achieve stability, until they accept that hard power is a blunt instrument capable only of wreckage. True strength lies in the capacity to compromise, to tolerate difference, and to engage the world through the sustainable lens of mutual respect.

Bibliography

Angell, Norman. The Great Illusion: A Study of the Relation of Military Power to National Advantage.London: William Heinemann, 1910.

Batmanghelidj, Esfandyar. “Drones Like Bicycles: The Real Economics of the Shahed Fleet.” Phenomenal World, March 11, 2026. Phenomenal World.

Boyle, Michael J., and Anthony H. Cordesman. Regime Change Revisited: The Intersecting Failures of Post-Conflict Governance and Hard Power. Washington, D.C.: Center for Strategic and International Studies, 2016.

Brown, Seyom. The Illusion of Control: Force and Foreign Policy in the Twenty-First Century. Washington, D.C.: Brookings Institution Press, 2003.

Brookings Institution.
Center for Strategic and International Studies. Assessing the Air Campaign After Three Weeks: Iran War By the Numbers. CSIS Missile Defense Project Report, March 25, 2026.

Cordesman, Anthony H. The Lessons of Ukraine and the Changing Nature of Asymmetric Attrition.Washington, D.C.: Center for Strategic and International Studies, 2024.

Fard, Erfan. “Iran Didn’t Need to Win the War. It Needed to Outlast It: AI Targeting and Strategic Geography in t
he 2026 Conflict.” Small Wars Journal, July 8, 2026. Small Wars Journal.

Malahila, Letsema. “The Contradictory Logics of International Intervention in Africa: Structural Fragility from Mobutu to Françafrique.” GIGA Focus Africa, no. 4 (2022): 1–9. GIGA Hamburg.

O’Hanlon, Michael E. The Porcupine Strategy: Asymmetric Sea Denial and Taiwan’s Defense Dilemma.Brookings Institution Policy Brief, 2025.

United Nations Department of Peace Operations. The Intervention Dilemma: 28 Years of Multilateral Peacekeeping and Political Vacuums in War-Torn States. New York: United Nations Blue Book Series, 2024.

Zenodo Research Repository. Iran’s New Grand Strategy, the Strait of Hormuz, and the Search for a Regional Security Order. Open-Access Strategy Paper, Archive ID 21707611, July 2026. Zenodo Records.



About Dawit W. Giorgis
Dawit W. Giorgis is originally from Ethiopia, US citizen, permanent resident of Namibia; served as P.S of Ministry of Foreign Affairs, Governor of Eritrea (prior to independence) and Relief and Rehabilitation Commissioner during one of the most publicised famine relief operations. He later served as UN consultant in 11 African conflict and post conflict countries; was a visiting fellow at Princeton University, University of Cape Town and Foundation for Defense of Democracies in Wash, D.C. at different times.
View all posts by Dawit W. Giorgis →

Thursday, October 01, 2026

'I'd rather die here than in Africa': Migrants describe violent deportation flight

Kate Linthicum
Tue, September 29, 2026
 Los Angeles Times.


A man in restraints boards an Eastern Air Express plane at Dallas Love Field on July 28 in Texas.
(Elias Valverde II / the Dallas Morning News via Getty Images)

On a tarmac in Texas, federal agents repeatedly ordered a group of shackled immigrants off a bus and onto an airplane that they had heard was destined for Africa.

Many complied, but some men refused. They had sought protection in the U.S. after fleeing repressive governments and asked to speak to lawyers before being deported to a faraway continent.

"Tell us where you're taking us," Kenis Adalberto López, a 44-year-old from Nicaragua, said he told immigration agents through tears. "I'd rather die here than in Africa."

Eventually, an agent boarded the bus and fired pepper balls at the men, according to interviews with three of them. López, who was hit twice in the chest with projectiles, said he was strapped to a stretcher and carried onto the plane, where he was restrained for the roughly 24-hour journey to Bangui, the capital of the Central African Republic.

More than 25,000 people have been expelled from the U.S. under a Trump administration program to deport asylum seekers and other migrants to "third countries" where they have no ties.

A federal appeals court ordered a pause on the program last week, saying the government failed to give migrants "a meaningful opportunity" to challenge their deportations to third countries. The Trump administration vowed to take the case to the Supreme Court, with Atty. Gen. Todd Blanche describing the program as "an entirely legal and invaluable tool to ‌stem the tide ‌of illegal immigration."

The administration has routinely said that its enforcement operations are carried out in compliance with federal law and that detainees are treated humanely.


People in restraints are seen standing outside a bus before boarding an Eastern Air Express flight at Dallas Love Field on July 28 in Dallas. (Elias Valverde II / the Dallas Morning News )

The Aug. 29 deportation of López and 42 others to Bangui highlights the sometimes violent tactics that officials have used to force detainees onto flights out of the U.S. — and the perils that await them once they land.

López and others recounted their journey in phone interviews from Africa.

The plane carried migrants from several countries, including Iran, Bangladesh and Afghanistan. Human rights lawyers say that many of them, including an Afghan man whose brothers worked with the U.S. military, had no criminal records and had been granted a special protection that barred them from being returned to their home countries because they had proved to a judge that they faced possible torture there.

Two of the men who resisted boarding the plane were kept in full-body restraint suits resembling straitjackets for much of the flight, according to witnesses. All of the deportees were shackled at the ankles and wrists while in the air.

After stops in two other African countries, the plane touched down in the Central African Republic, one of the world's poorest nations and the site of an ongoing civil war between Muslim and Christian rebels that has claimed tens of thousands of lives over the last 15 years. The primary languages are Sango and French.

The migrants were given shots for yellow fever and taken to a housing complex, where they remain today, monitored at all times by armed guards.


Workers unload a truck containing bags full of onions coming from Cameroon to Bangui in the Central African Republic on March 5, 2025. (Patrick Meinhardt / AFP via Getty Images)

Bangui, which sits across a wide river from the Democratic Republic of Congo, is battling a recent cholera outbreak and faces water shortages and power outages.

Crime is rampant, with the U.S. government itself warning Americans not to visit the Central African Republic because of "unrest, crime, kidnapping, landmines, health issues and terrorism."

Three flights carrying U.S. deportees have arrived there since June, according to human rights groups tracking the issue. Many complain that U.S. immigration agents confiscated their identity documents upon detention and never returned them, making it all but impossible to leave the country. Their immigration status in the Central African Republic is unclear.

Two men who arrived on a July 31 flight recounted being kidnapped on the street by armed men who they believe were police officers.

Yasmani Moreno said he and the other detainee each had to pay the equivalent of $100 to be released.

Moreno, 31, who arrived in Florida on a raft from Cuba in 2016, was initially allowed to stay in the U.S. under the "wet foot, dry foot" policy, which until 2017 let Cubans who reached U.S. soil remain in the country. His temporary permit expired before he obtained a green card.

He has documented his time in Africa extensively on TikTok, taking his followers for walks along Bangui's muddy streets. "They sent me to a failed state," he said in an interview.


Campaign billboards in Bangui, capital of the Central African Republic, tout President Faustin-Archange Touadera, center, and other candidates in 2025. Touadera's government has agreed to accept third-country deportees from the United States. (Annela Niamolo / AFP via Getty Images)More

After decades of coups and strife, government forces have sought to disband many militia groups there, sometimes with the help of mercenaries with the Wagner Group, a Russia-based military contractor accused of human rights abuses. International experts have denounced President Faustin-Archange Touadera's repression of the opposition and push to eliminate term limits as worrisome turns toward autocracy.

For deportees who came to the U.S. after fleeing authoritarian countries, an unknown future in another undemocratic nation is frightening.



Luis Mendoza Santamaría, 38, left, stands with other migrants in Bangui, Central African Republic, on Sept. 23. . (Anela Faustina / For The Times)

Luis Mendoza Santamaría , 38, escaped Nicaragua after he marched in 2018 pro-democracy protests that were violently suppressed by the left-wing Sandinista government. He asked for political asylum at the U.S. border. A judge denied his request, but granted him protection from deportation under the international Convention Against Torture. For years, he led a quiet life working as a waiter in hotels in Washington, D.C.

In the past, people with such protection were generally allowed to stay and work in the U.S. indefinitely.

But in February, Mendoza went to a regular immigration check-in and was detained. He was held in jails across the U.S., he said, until he was taken by bus to the tarmac in Texas on Aug. 28.

President Trump, in his push to expel 1 million people annually, has vastly expanded the pool of migrants eligible for deportation, with asylum seekers and people who a judge said may be tortured upon return now making up a growing share of detainees.

The U.S. has earmarked around half a billion dollars in aid to third countries who agree to take deportees, according to an investigation by the nonprofit journalism consortium Forbidden Stories, which found that in some cases, deportees sent to third countries were later returned against their will to their home nations.

"This is a deliberate attempt by the Trump administration to place refugees whom the U.S. government has determined need protection directly in harm's way," said Savi Arvey, director of policy for refugee and immigrant rights at Human Rights First.


Luis Mendoza Santamaría, who came to the U.S. from Nicaragua, said he was never notified that he was going to be deported to Africa. (Anela Faustina / For The Times)

Mendoza said he was never notified that he was going to be sent to Africa — but that he and fellow deportees had heard rumors about flights there and suspected their fate when they saw the size of the plane they were being ordered to board. He said he was struck twice in the back and once in the knee with canisters containing pepper spray after he resisted boarding; pains from the blows persist.

After arriving in Bangui, he said, he went days without eating and sleeping, and suffered what he described as a mental breakdown.

"This is inhuman," he said. "It's psychological violence."


A bronze statue of the late Wagner Group chief Yevgeny Prigozhin, left, and his top aide, Dmitry Utkin, in front of the Russian House in Bangui in 2024. (Annela Niamolo / AFP via Getty Images)

He is worried in particular about ties between the Central African Republic and Russia, which is an ally of Nicaragua's Sandinista government.

Sandinista operatives are suspected in a series of shootings, abductions and killings of Nicaraguan exiles in Costa Rica in recent years. Mendoza wonders whether he is safe.

He has been following the news in the U.S. — including the recent appeals court ruling against the third country deportation program. His lawyer has urged him to look for another country that might grant him political asylum, but Mendoza still holds out hope that the U.S. will welcome him back.

"There will be justice," he said. "There's still a democracy there."

Linthicum reported from Mexico City. Special correspondent Ismael López in Jacksonville, Fla., contributed to this report.



Tuesday, September 22, 2026

25 Years After Amerithrax: The Changing Landscape Of Biosecurity – Analysis




September 21, 2026
Manohar Parrikar Institute for Defence Studies and Analyses (MP-IDSA)

By Aayushi Sharma and Ajey Lele


Key Takeaways:

The case never quite closed. Anthrax letters after 9/11 killed five. FBI shut Amerithrax in 2010 on USAMRIID’s Bruce Ivins (suicide, 2008); Hatfill won a settlement after a false-accusation suit. An independent review said the evidence fit Ivins but did not prove him. Brief: bioterror became health, police, intel, and security at once.

What followed. U.S. Bioterrorism Act (2002), Project BioShield (2004), DHS BioWatch. WHO IHR (2005), GHSI (2001). Surveillance now includes wastewater, pharmacies, animals, plants—One Health with WOAH and FAO still loosely joined. Attribution stays hard; the text notes mail, air, and other paths without a recipe.

Dual-use and a thin treaty. Synthesis, editing, and AI speed vaccines and sequencing; consortium DNA-order checks are mostly voluntary. The brief flags LLM and dual-use risk, not a method. BWC still lacks verification and a standing S&T body; 2011 review named terrorism; UNSCR 1540 and the Australia Group fill gaps. COVID showed accident and attack share the same kit. Author: keep funding detection, stockpiles, and the talks.


The 2001 anthrax attacks in the US led to the emergence of biological terrorism as a public health, law enforcement, intelligence, and national security problem, highlighting the need for an integrated approach to addressing the threat. Advances in biotechnology, synthetic biology, and emerging technologies have defined the biological threat landscape over the past 25 years.


Introduction


The deadly attacks of 11 September 2001 were followed by another critical terrorist incident in the United States, wherein anonymous letters laced with the deadly anthrax spores were sent to several media companies and post offices. The attacks claimed the lives of five people through the inhalation of anthrax and infected several others who came in contact with the postal envelopes. The Federal Bureau of Investigation (FBI) codenamed the investigation ‘Amerithrax’.[1] The ‘Amerithrax Task Force’ was created to determine the source of this terrorist attack. The FBI subsequently released an ‘Amerithrax Investigation Report’ detailing the course of the investigation.[2] The investigation focused primarily on scientists associated with the US biodefence establishment, especially the US Army Medical Research Institute of Infectious Diseases (USAMRIID) at Fort Detrick, Maryland.


The investigation subsequently went through a series of phases which were deemed controversial. Several scientists were designated as ‘persons of interest’ and came under surveillance and investigation. In several cases, the suspects also pushed back against the allegations of deliberately releasing anthrax. One known suspect, Steven Hatfill, a pathologist and a biological weapons expert, ultimately received a large government settlement after pursuing legal action over being falsely accused in connection with the attacks.[3] In 2008, another biodefence scientist, Bruce Ivins, a senior biodefence researcher at USAMRIID who was identified as the principal suspect, died by suicide.[4] The FBI formally closed the investigation in 2010, concluding that Ivins was the actual culprit and that he had acted alone. However, an independent scientific review found that the evidence was consistent with Ivins being the culprit, but still inadequate to conclusively establish his responsibility.[5]

Along with the rapid investigations, the anthrax attacks also triggered a major national public health and law enforcement response, widespread disruption to postal services, and extensive decontamination efforts. Executed only a week after one of the worst terrorist attacks in modern history, the anthrax attacks added to the already heightened threat perceptions regarding terrorism. As a result of these attacks, biological terrorism emerged as a public health, law enforcement, intelligence, and national security problem, highlighting the need for an integrated approach to addressing the threat. Biological terrorism or bioterrorism, however, was not a novel phenomenon. There have been numerous accounts of non-state actors using or attempting to use hazardous biological materials as weapons to create widespread harm.[6]


This brief addresses response mechanisms, bio-surveillance, and emerging technology challenges to contextualise where the world stands today on bio-preparedness, 25 years after the 2001 Anthrax attacks. It explores the critical implications and opportunities for the Biological Weapons Convention (BWC) in shaping the future of global biosafety and biosecurity. The brief evaluates how two-and-a-half decades of science, technology, and policy evolution have shaped our preparedness against biological and toxic threats, and the challenges that persist.

Biodefence and Response Mechanisms

Response mechanisms and biodefence are a critical interdisciplinary field focused on protecting human life and agriculture. Key organisations involved include laboratories studying biological science, agricultural research centres, medical sciences, public health agencies, pharmaceutical companies, and national security agencies. Over the last 25 years, states worldwide have developed specific agencies associated with biological threats. Some states have developed advanced biodefence strategies and institutional mechanisms, while others are still working on them. It is also important to recognise that this threat has always been dynamic, so continued attention is required when deciding on response mechanisms and biodefence practices.

When it comes to addressing the risks posed by biological weapons, it is important to focus on the unique characteristics and vulnerabilities regarding biological agents. These agents include infectious pathogens and biotoxins that are non-transmissible. These weapons often have delayed effects and variable incubation periods, which add to the challenges of building robust response mechanisms for such threats. The case of anthrax attacks in the US made it fundamentally clear that investigations into biological weapons attacks are often met with attribution challenges. The challenge of effective attribution persists and is often exacerbated by rapid advances in biotechnology and easily accessible biological design tools.


The fragmented nature of biological weapons dissemination also challenges preparedness and response. While in the US, anthrax spores were dispersed through the postal mail, such agents can also be disseminated through aerosols or even contamination of important resources such as crops or water supplies, causing widespread damage. Therefore, as these threats rapidly evolve, delivery mechanisms for such agents are easily accessible to non-state actors, further complicating attribution.

The 2001 anthrax attacks exposed massive vulnerabilities in the public health detection and response systems, intelligence gathering, and inter-agency coordination mechanisms in the US. The US hence worked to build national capacities through the Public Health Security and Bioterrorism Preparedness Act of 2002 to strengthen prevention, preparedness, and response mechanisms against biothreats and to develop stringent standards for securing dangerous biological agents. The Act also imposed strict regulations on the possession, use, and handling of specific biological agents. To build on these response capabilities, Congress enacted the Project BioShield Act in 2004, which incentivised companies to research, develop, and stockpile medical countermeasures against CBRN threats.[7] Incentivising research in medical countermeasures also heightens capabilities to address novel bio-risks and leverage technological advancements to improve detection and response mechanisms.


Globally, funding surged for biodefence and preparedness research, as well as for high-containment facilities, to build scientific, defence, and policy capabilities to counter such threats.[8] The preparedness gaps to deal with bioterrorism threats were significantly highlighted in the aftermath of the anthrax attacks. The World Health Organization (WHO) developed the International Health Regulations in 2005 to legally require signatory countries to build national capacities for detecting, analysing, and surveilling public health emergencies of international concern.[9]

Additionally, the Global Health Security Initiative (GHSI) emerged in 2001 as a cross-regional multilateral grouping to improve cooperation in public health preparedness mechanisms to respond to CBRN terrorism threats, with WHO as the technical advisor.[10] The anthrax attacks thus led to growing attention on improving biodefence, international coordination in public health preparedness, and response capabilities, not just within the US but worldwide.

Thus, in 2001, bioterrorism emerged as a pressing challenge requiring coordination across public health, national security, and law-and-order agencies. However, contemporary issues relating to emerging technologies, AI integration, dual-use research of concern (DURC), and the evolving capabilities of biotechnology are creating new pathways to biological misuse and redefining the biosecurity landscape.

Bio-Situational Awareness and Intelligence Gathering Mechanisms


One of the most effective ways to address novel threats is to build robust disease surveillance systems that track unusual occurrences that may signal a public health emergency. Disease surveillance is therefore a key pillar of early recognition and detection. Bio-surveillance essentially involves gathering and analysing relevant data to provide periodic information on biological threats affecting human, animal, plant, and environmental health. Strong bio-surveillance systems build bio-situational awareness and early detection, improving national and global capacities to address bio-risks.


Various approaches may be used to develop such systems, such as syndromic surveillance, which involves gathering data through public health officials reporting on suspected threats based on the reported symptoms of a given population, or event-based surveillance, which involves a wider range of information systems involving newspaper reports, social media, or publicly reported incidents.[11] Epidemiological studies have also become central to early detection by understanding disease patterns and transmission.

However, the anthrax attacks revealed that public health surveillance may not only deal with accidental bio-risks but also deliberate attacks. The resulting policy shift led the US to treat biological risks as a national security problem. The Department of Homeland Security created the BioWatch system as a direct result. BioWatch served as an early-warning system to detect the aerosolised release of certain pathogens through a network of sensors.[12]

Gathering public health data and developing bio-situational awareness is beneficial not only in the context of deliberate biothreats but also accidental ones. Therefore, even after 25 years of terrorist attacks using anthrax, efforts are underway to develop global bio-surveillance mechanisms to build transnational capacities to tackle such threats. Integrated bio-surveillance efforts would require simultaneous data collection from several sources, including public health institutions, high-containment laboratories, pharmacies and wastewater facilities.[13] Current efforts extend surveillance beyond public health data to include animal, plant, and environmental health. This One Health approach to bio-surveillance and intelligence gathering requires active global cooperation frameworks that go beyond national implementation.[14]


To build global coordination mechanisms, organisations like the WHO have worked to develop early warning detection systems and transnational response systems to address the threats posed by pathogens with pandemic potential. WHO has several initiatives, including the International Pathogen Surveillance Network (IPSN) and the Global Outbreak Alert and Response Network (GOARN), which provide technical coordination to identify and respond to public health emergencies.

The Epidemic Intelligence from Open Sources Initiative (EIOS) and the WHO Hub for Pandemic and Epidemic Intelligence also provide technical assistance to countries to improve detection and monitoring capabilities.[15] While these initiatives exist, building an integrated approach to intelligence sharing and data gathering, along with inter-agency coordination, such as the World Organisation for Animal Health (WOAH) and the Food and Agriculture Organization (FAO), for a One Health framework remains a challenge.

Translating these bio-surveillance capabilities into effective early warning systems also comes with its own set of nuances. For global early warning systems to work well in deliberate and accidental disease outbreaks, capacities need to be built towards interoperable systems capable of operating in diverse demographic and geographic settings.[16] One major driver of continued efforts to build better, more integrated bio-surveillance, early warning, and detection systems is the increased perception of biological risk in recent years. Even after more than two decades of anthrax attacks, the challenge of keeping biological weapons capabilities out of the hands of non-state actors persists due to the novel risks posed by artificial intelligence (AI) as well as developments in biotechnology.

Emerging Technologies: Boon and Bane

Rapid advances in biotechnology, synthetic biology, gene editing, AI and related technologies are strengthening biodefence while simultaneously lowering barriers to biological misuse. Developments in biotechnology continue to offer immense potential to enhance biological defence capacities by supporting research into rapid detection, diagnosis, and improved medical countermeasures, including vaccine development and other prophylactic treatments. Advances in life science research capabilities have also expanded the potential of gene sequencing methods such as metagenomic sequencing to provide simultaneous, independent analysis of the total genetic material in a sample.[17]

Biotechnology developments, when considered alongside accessible AI integration, also present opportunities to improve drug discovery, vaccine development, and other pharmaceutical interventions. AI models can also help with biological data analysis, as well as structuring and synthesising large databases to support research. Targeted attention is also being paid to improving medical measures against drug-resistant bacteria and viruses through frontier AI models along with improved gene editing capabilities.[18] Therefore, a case can be made for responsible and governed use of AI in biotechnology and life science research. This integration could help address longstanding concerns and improve the biosecurity landscape.

While the opportunities presented by AI and biotechnology are widely recognised, they are also accompanied by concerns about potential risks, especially in the absence of integrated governance and regulatory frameworks. Improvements in biotechnology capabilities over the years have also created space for faster, cheaper, and more accessible DNA synthesis technologies, driving market expansion among DNA synthesis providers. However, screening protocols for ordered DNA sequences have not been implemented to the same extent.

These capabilities require structured, standardised, and uniform screening regulations to verify customer identities comprehensively. These regulations are crucial for ensuring that DNA sequences of potentially dangerous pathogens are only provided to legitimate research facilities with adequate institutional biosafety standards in place. Currently, DNA providers primarily belong to the International Gene Synthesis Consortium, a commercial group of providers in the global market.[19] The Consortium has established the Regulated Pathogen Database (RPD) to verify given orders and detect the sequences of concern.[20]

They may either conduct customer screening to establish the identity of the ordering parties or screen the sequences ordered to identify potentially dangerous and controlled pathogens or biotoxins. However, without a legal mandate within the Consortium, screening DNA synthesis orders before fulfilment is largely voluntary. This staggered safeguards landscape creates gaps in screening and contributes to biosecurity concerns about unregulated access to hazardous biological materials.

The integration of AI into this biotechnology landscape therefore adds another layer of complexity. While certain frontier AI models may be instrumental in synthesising large datasets to aid biological research, they may also lower technical thresholds, especially open-source large language models (LLMs), by disseminating information on biological design.[21] A study auditing 32 LLMs found that most complied with requests to design and generate novel toxin sequences.[22] Similarly, recent scientific research shows that generative AI models can develop genome sequences for novel viruses that target bacteria resistant to natural bacteriophages.[23] This development also raised concerns about diverting these capabilities to engineer drug-resistant, human-infecting viruses.


Safeguards on the end of AI developers also become significant in this case. Anthropic’s newer models have safety classifiers in place, with evaluations conducted on refusal benchmarks to assess the models’ ability to handle prompts related to the hazardous use of biological weapons.[24] However, despite these mechanisms, Anthropic’s recent threat assessment report revealed several attempts to bypass the safety classifiers and retrieve questionable information on gene editing of infectious pathogens and toxin design.[25] Thus, in the context of deliberate biothreats, greater access to bio-design tools and open-source AI platforms equipped with the requisite knowledge are among the most pressing challenges in the current global biosecurity discourse.


Strengthening Global Norms for Biosecurity


Biosecurity is a crucial pillar of the international security architecture. Considering the broad spectrum of biological risks, ranging from natural and accidental outbreaks to deliberate weaponisation of infectious pathogens and biotoxins, the global norms on biosecurity are embedded in various institutional mechanisms. Major international frameworks on deliberate biothreats include the Biological and Toxin Weapons Convention (BTWC) and UNSCR 1540, while the WHO sets norms for public health issues such as biosafety standards, disease surveillance, detection, preparedness, and response mechanisms. The voluntary export control groupings such as the Australia Group are significant in managing transnational trade in controlled substances with relevance to chemical and biological weapons.

The ‘biological weapon taboo’, or the perceptions against the use of biological materials as weapons, was recognised through the prohibition of use under the 1925 Geneva Protocol.[26] This development was further strengthened and legally enforced through the Biological and Toxin Weapons Convention (BTWC), which entered into force in 1975.[27] While the BTWC has largely succeeded in establishing the norm against biological weapons, contemporary challenges relate to enforcing these norms through practical frameworks that adequately address emerging risks.

The Convention legitimises the use of biological materials for peaceful life science research while prohibiting any use not intended to be peaceful. In theory, this may seem like a significant qualifier for what the regime permits and prohibits. However, questions and uncertainties arise as the dual-use characteristics of life science research and subsequent AI integration in biotechnology take shape.

With frontier AI models, scientists are increasingly studying capacity-building in medical countermeasures to address drug-resistant pathogens, which requires careful use of gene-editing technologies. However, the same capabilities can also be diverted towards more lethal use of genetically engineered pathogens for harmful purposes. Therefore, without international verification mechanisms, determining the legitimacy of biological research for peaceful purposes becomes a mammoth challenge for the existing regime.

Current structural challenges in the Convention also include the lack of a Science and Technology Advisory Body to monitor and routinely conduct a scientific review of the treaty. This development would be necessary to adequately assess the Convention’s capacity to address emerging biosecurity risks. The ongoing working group discussions to strengthen the Convention are a significant step forward in this regard. The Convention’s scientific capacities can also be enhanced by developing networks of high-containment laboratories with strong biosafety standards.


The Organisation for the Prohibition of Chemical Weapons (OPCW) has provided a precedent for such a structure, with designated biomedical and environmental facilities also in place.[28] Such a network for the BTWC could facilitate independent, regulated research into sequencing novel pathogens and toxins to develop stronger verification mechanisms for the treaty. Building effective regulatory practices without infringing on or curtailing scientific progress is a pressing challenge for the BTWC.

Alongside laboratory security measures, research verification, international cooperation and compliance, efforts to prevent misuse by non-state actors are also significant to strengthening global biosecurity norms. The anthrax attacks of 2001 widened the perceptions around biosecurity to include the threats posed by non-state actors as well as inadequate regulatory oversight of research facilities. Hence, stronger norms backed by practical frameworks are essential for improving biosecurity in response to bioterrorism threats.

Deliberations at BWC review conferences signal a careful yet staggered recognition of the threat of bioterrorism. The final declaration of the seventh review conference of 2011, for the first time, condemned terrorism ‘in all its forms and manifestations’ in the context of using biological agents, further highlighting the role of UNSCR 1540.[29] In the absence of verification and implementation mechanisms for the Convention, instruments such as UNSCR 1540 and its oversight mechanism through the 1540 Committee provide important frameworks for advancing global security protocols against bioterrorism.[30]

Given the plethora of emerging challenges surrounding synthetic biology, open-source AI models, and rapidly evolving biotechnology capabilities, institutionalising appropriate safeguards and building an integrated approach is essential to strengthening biosecurity normative frameworks.

While the anthrax attacks presented a case of deliberate use of biotoxins to inflict harm, hence a biological weapons attack, the experience of COVID-19 presented the need to consider pandemic preparedness and response as an international security issue.[31] Many response and biodefence capabilities that support defence against accidental biothreats and natural outbreaks also support defence against deliberate threats. Thus, lessons should be learned from the COVID-19 pandemic of 2020, and the institutional inadequacies that hindered global coordination should be addressed to build international capacity.

Conclusion


The anthrax attacks of 2001 revealed that mitigating biological threats requires an integrated approach towards bringing together public health, law enforcement, bio-surveillance and national security frameworks. Twenty-five years later, amid a rapidly advancing emerging risk landscape, the reality remains the same. The COVID-19 pandemic of 2020 is particularly significant in this regard. The pandemic exposed gaps in current detection and preparedness capabilities and underscored that global biodefence mechanisms must support robust, transnational early detection and response.


Developments in biotechnology, synthetic biology, gene editing, and AI models offer immense opportunities to advance life science research. Still, they also heighten concerns about access to biological materials, lowered technological thresholds, and deliberate misuse. While AI integration in biotechnology cannot replace tacit laboratory knowledge, institutions need to strengthen biosafety mechanisms and regulatory oversight to prevent accidental exposure and outbreaks. Similarly, safeguards around DNA synthesis acquisition and screening mechanisms are essential to reduce perceived threats around the availability of controlled and high-risk sequences.

Additionally, effective bio-surveillance mechanisms become important for improving early-warning systems, preparedness, and detection capabilities. While national frameworks for addressing bio-risks exist in practice, existing international frameworks are still essential for building multilateral and transnational capacity against these risks. Efforts are underway to address longstanding issues in the BTWC, especially regarding legally binding verification mechanisms, international assistance and cooperation, and stronger compliance.[32] While these developments largely reflect state obligations, continued deliberations on threats posed by non-state actors are also crucial within the Convention.

After more than two decades, the anthrax attacks provide a strong vantage point to evaluate the priorities of the existing biosecurity landscape. The experience of anthrax and COVID-19 indicates that biological threats cannot be treated simply as low-probability possibilities. Sustained investment in prevention, detection, attribution, medical countermeasures, and international cooperation remains essential


Source: 
This article was published by the Manohar Parrikar IDSA “Amerithrax or Anthrax Investigation”, 

Federal Bureau of Investigation.

The New York Times, 19 February 2010.
“Scientist Officially Exonerated in Anthrax Attacks”, The New York Times, 8 August 2008.

Gregory Frederick, “A Review of The Mirage Man: Bruce Ivins, the Anthrax Attacks, and America’s Rush to War”, Journal of Microbiology & Biology Education, Vol. 12, No. 2, pp. 211–212.

“Timeline: How the Anthrax Terror Unfolded”, National Public Radio (NPR), 15 February 2011.

Stephan Riedel, “Biological Warfare and Bioterrorism: A Historical Review”, Baylor University Medical Center Proceedings, Vol. 17, No. 4, 2004, pp. 400–406.

“Project BioShield”, Administration for Strategic Preparedness and Response.

Carrie M. Long and Andrea Marzi, “Biodefence Research Two Decades Later: Worth the Investment?”, The Lancet Infectious Diseases, 1 August 2021.

“International Health Regulations”, World Health Organization.

Natasha E. Bajema, William Beaver and Christine Pathemore, “Toward a Global Pathogen Early Warning System: Building on the Landscape of Biosurveillance Today”, Council on Strategic Risks, 20 July 2021.

“The BioWatch System”, in BioWatch and Public Health Surveillance: Evaluating Systems for the Early Detection of Biological Threats, National Academies Press, 2011.

Vijey Nema, “Biosurveillance”, Microbial Diversity in the Genomic Era, 2019.

Nithin Ramakrishnan, “Bio-surveillance as One Health: A Critique of Recent Definitions and Policy Initiatives”, Development, Vol. 66, 2023, pp. 215–225.

“International Pathogen Surveillance Network”, World Health Organization; “The Global Outbreak Alert and Response Network”, World Health Organization; “Epidemic Intelligence from Open Sources (EIOS)”, World Health Organization; “The WHO Hub for Pandemic and Epidemic Intelligence”, World Health Organization.

“Global Early Warning System: Safeguarding Against Future Pandemics”, Food and Agriculture Organization of the United Nations.

Torsten Thomas, Jack Gilbert and Folker Meyer, “Metagenomics – A Guide from Sampling to Data Analysis”, Microbial Informatics and Experimentation, 9 February 2012.

Amir Elalouf, Hadas Elalouf, Ariel Rosenfeld and Hanan Maoz, “Artificial Intelligence in Drug Resistance Management”, Biotech, Vol. 15, No. 5, 2025.

Tanya Sarawagi and Suryesh K. Namdeo, “The Double Helix of Danger: Securing Synthetic DNA in India”, Occasional Paper, Observer Research Foundation, 27 August 2026.

Shu Quan, Tianfang Hao, Sitong Fang, He Geng, Jiayi Zhou, Boyuan Chen, Kaile Wang, Donghai Hong, Juntao Dai, Yaodong Yang and Jiaming Ji, “A Blind Spot in Alignment: Quantifying Biosecurity Risks in Large Language Models”, arXiv, 5 August 2026.

Samuel H. King, Claudio L. Driscoll, David B. Li, Daniel Guo, Aditi T. Merchant, Garyk Brixi, Max E. Wilkinson and Brian L. Hie, “Generative Design of Bacteriophages with Genome Language Models”, Science, Vol. 393, No. 6811, 2026.

Phillip M. McCauley and Roger A. Payne, “The Illogic of the Biological Weapons Taboo”, Strategic Studies Quarterly, Vol. 4, No. 1, 2010, pp. 6–35.


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Views expressed are of the author and do not necessarily reflect the views of the Manohar Parrikar IDSA or of the Government of India.

About the authors:

Aayushi Sharma is a Research Analyst at Manohar Parrikar Institute for Defence Studies and Analyses (MP-IDSA), New Delhi.

Group Captain (Dr) Ajey Lele (Retd.) is the Deputy Director General, MP-IDSA. Earlier, he was a Senior Fellow at the Manohar Parrikar Institute for Defence Studies and Analyses and a part of its Centre on Strategic Technologies. He started his professional career as an officer in the Indian Air Force, and took early retirement from the service to pursue his academic interests. He has a Masters degree in Physics from Pune University, and Masters and MPhil degrees in Defence and Strategic Studies from Madras University.



About Manohar Parrikar Institute for Defence Studies and Analyses (MP-IDSA)

The Manohar Parrikar Institute for Defence Studies and Analyses (MP-IDSA), is a non-partisan, autonomous body dedicated to objective research and policy relevant studies on all aspects of defence and security. Its mission is to promote national and international security through the generation and dissemination of knowledge on defence and security-related issues. The Manohar Parrikar Institute for Defence Studies and Analyses (MP-IDSA) was formerly named The Institute for Defence Studies and Analyses (IDSA).
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Tuesday, September 15, 2026

Mosquito waste reveals viruses hiding in plain sight



A new approach to capture waste from mosquitoes could strengthen early warning systems for emerging health threats




Rutgers University

Scientist in field with device

image: 

Dana Price of the Rutgers Center for Vector Biology sets a mosquito-waste collection trap in the field as researchers work to adapt the approach for real-world surveillance.

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Credit: Dana Price/Rutgers University





When public health researchers want to know whether diseases such as COVID-19 or polio are circulating in a community, they can look for genetic evidence in wastewater.

Entomologist Dana Price wondered whether the same principle could be applied to mosquitoes. The question led to an unconventional experiment.

“What we did, colloquially, was build a mosquito toilet,” said Price, an associate professor at the Center for Vector Biology, Department of Entomology in the School of Environmental and Biological Sciences and a lead author of a study published in Microbiology Spectrum.

The device, Price said, is deceptively simple: a 3D-printed funnel coated with a superhydrophobic (water-repelling) material that causes liquid to bead up and slide into a collection tube.

The tiny traces of mosquito waste it captured revealed a hidden world.

By sequencing genetic material in mosquito excrement, Price recovered a complete West Nile virus genome, found the first known evidence of a Hedwig-like virus in the Americas and detected several viruses that may be new to science. The approach also identified parasites and confirmed the mosquito species that deposited the waste droplets.

Findings from the study suggest mosquito waste could become a powerful surveillance tool, allowing scientists to search broadly for familiar pathogens as well as threats they don’t yet know exist, Price said.

“If you don’t look for it, you won’t find it,” Price said. “But what if you don’t know what to look for?”

Mosquito surveillance historically involves collecting large numbers of insects, sorting them by species, combining them into pools and grinding them up for laboratory testing.

The labor-intensive process requires scientists to preserve the insects carefully, so their genetic material doesn’t degrade. During an outbreak, those steps can delay information needed to direct mosquito-control efforts. Conventional tests also target specific pathogens, so researchers must know what they are looking for.

Mosquitoes excrete small amounts of liquid containing genetic traces of viruses and other organisms. Because the waste contains far less mosquito tissue, and therefore less mosquito DNA, than a crushed insect, the scientists reasoned that viral material might be easier to find.

The researchers collected two groups of 50 wild Culex mosquitoes from a yard in New Brunswick, N.J., in 2021 and 2022. They placed each group in a screened container over the funnel and fed them a sugar solution. The mosquitoes produced drops of waste, which slid into a tube.

The scientists used shotgun metagenomic sequencing – used to sequence all genetic material present in a mixed sample. Computers then assembled the millions of fragments generated and compared them with known sequences in scientific databases.

The 2022 sample contained a complete, high-quality genome of West Nile virus, which can cause serious neurological illness in people.

The researchers identified the virus as belonging to the NY07 genetic variant previously found in the region. Such detail eventually could help scientists track how genetic variants of a virus emerge,spread and change.

“What came out was an entire viral genome,” Price said. “Rather than just positive or negative, we have genetic data.”

The researchers were even more intrigued by evidence of a Hedwig-like virus, which hadn’t previously been reported in the Americas.

Hedwig virus was first identified in Europe in snowy owl tissue, prompting scientists to name it after Harry Potter’s famous white owl. Some of the infected birds also hadWest Nile virus .

Scientists don’t know whether Hedwig-like viruses make birds sick, facilitate West Nile infections or simply coexist with other viruses. The Rutgers finding doesn’t establish that the virus is a threat, Price said. It shows that it has been circulating where no one knew to search for it.

“We didn’t even look for it specifically,” Price said. “We just looked for everything, and we found Hedwig in there.”

He currently is working with officials at the New Jersey Department of Environmental Protection’s Division of Fish and Wildlife to screen organ and tissue samples for the virus. The samples are collected from deceased birds during a post-mortem examination.

A virus found for the first time in a region may have recently arrived or may have gone unnoticed for years. Because few broad mosquito-virus studies have been conducted in North America, organisms that seem geographically restricted may prove widespread.

“The more data we generate, the more we start to wonder if everything is everywhere,” Price said. “Although we don’t yet know how much of everything is everywhere, it may be a lot more than we realize.”

The samples also contained sequences so different from known examples that the researchers classified the viruses as potentially new. They included a partiti-like virus, a picorna-like virus and a possible new virus associated with single-celled parasites infecting the mosquitoes. More study is needed to confirm they are previously undescribed species.

Most appear to infect mosquitoes, other insects or microorganisms living inside mosquitoes and are not known to cause human disease. Some insect-specific viruses may even interfere with mosquitoes’ ability to carry West Nile, dengue or Zika viruses.

The waste also contained traces of trypanosomatids, a group of single-celled parasites known to infect mosquitoes. Mosquito DNA confirmed that the insects belonged primarily to the Culex pipiens group, a West Nile carrier.

Price said the research was an initial demonstration, not a replacement for existing surveillance. It examined 100 mosquitoes from one location, which were transferred to the funnel in a laboratory.

Researchers also cannot conclude from waste alone that a mosquito can transmit a virus, Price said. It could be infecting the mosquito or another organism inside it or simply passing through.

For now, the technique can answer a broader question: Is a pathogen circulating in this environment?

The team is working toward a field-ready trap that would collect mosquitoes and their waste. Price eventually envisions a system that could prepare samples, sequence genetic material, analyze the results remotely and alert scientists to a possible threat in real-time.

“The pie-in-the-sky idea is a device that we place in a forest somewhere, and it’s constantly just beaming back data to us,” Price said.

Such a system could be especially valuable in remote or resource-limited areas, he said. It could reveal known pathogens before they cause widespread illness and expose the ones no one yet knows to look for.

Other Rutgers researchers on the study include: Mehdi Javanmard from the Department of Electrical and Computer Engineering in the Rutgers School of Engineering; Taewon Han, an assistant research professor from the Department of Environmental Sciences in the School of Environmental and Biological Sciences; Nicole Wagner, a laboratory researcher; and former undergraduate students Miranda Barnes and Fiona Bezhani.

Explore more of the ways Rutgers research is shaping the future.