Thursday, April 27, 2023

How evolution has influenced the shape of the brain

MedUni Vienna is conducting research into the connections between brain structure and function in humans and animals

Peer-Reviewed Publication

MEDICAL UNIVERSITY OF VIENNA

The connections between the structure of the brain and its function are a key focus of neuroscience. A new Medical University of Vienna study involving a team of international partners has been looking at evolution and its relationship with the capabilities of human and animal brain architecture. The findings showed that the shape of the brain has developed in parallel with the organ’s function throughout the course of evolution. The results of the study were published in the renowned journal Nature Communications.

In the study, 3D surface models of the brains of 90 species of Euarchontoglires (supraprimates), such as humans, macaques, marmosets, mice, rats, squirrels and hamsters, were examined. Computer-based modelling of common ancestors and analysis of the shapes of neuronal structures was used to create a common representation of the brains. For the first time, this made it possible to analyse the diversity of brain forms and their relationship to function, behaviour and ecology, i.e. the relationship between living beings and their environment.

The results confirm that the shape of the brain has developed in parallel with the organ’s function over the course of its evolution. "By evaluating the various growth patterns, we were able to identify seven clusters that expanded together during the evolution of the brain and which correspond to specific aspects of cognitive abilities in animals and humans," explained lead author Ernst Schwartz from the Computational Imaging Research Lab (CIR) at MedUni Vienna's Department of Biomedical Imaging and Image-guided Therapy. As a result, the brain adapts to its environment by first expanding its visual attention areas before other areas involved in higher cognitive functions, such as language and memory.

The study was conducted in partnership with researchers from all over the world. “The study would not have been possible without the exceptionally open, interdisciplinary, international cooperation that characterised it. It combines elements of neuroscience, anatomy, palaeontology, and mathematics – and involved more than a dozen laboratories around the world," said study director Georg Langs. "One of the triggers for this work was an interest in plasticity – the question of why it is that some brain regions are better able to reorganise themselves during an illness than others. And we hope that a better understanding of the geometry of the brain will help us gain insights into these mechanisms," he concluded. The research outcomes could also aid better understanding of the common – and different – characteristics between animals and humans.

Web: www.cir.meduniwien.ac.at/evolution

Swedish icebreaker Oden departs for Arctic expedition to study onset of melting season

Business Announcement

STOCKHOLM UNIVERSITY

Icebreaker Oden in the port of Helsingborg in southern Sweden. 

IMAGE: ICEBREAKER ODEN IN THE PORT OF HELSINGBORG IN SOUTHERN SWEDEN. view more 

CREDIT: SWEDISH POLAR RESEARCH SECRETARIAT

On April 28th, the icebreaker Oden will depart from a Swedish port for the research expedition called ARTofMELT 2023 in the Arctic Ocean. The researchers will study the arrival of spring in the Arctic and the beginning of the melting season.

"The weather is ultimately driven by the temperature difference between the polar regions and the equator. As the Arctic warms up much faster than the rest of the world, the conditions for weather and climate across the entire Northern Hemisphere are changing. The effects of disappearing ice in the Arctic do not stop there," says Michael Tjernström, Professor of Meteorology at Stockholm University.

During the spring, the Swedish Polar Research Secretariat has worked intensively to prepare and adapt the Oden for this early expedition. Recently, the researchers gathered in Helsingborg's port in southern Sweden to load equipment onboard and install research instruments. The expedition also includes Swedish visual artist Ida Rödén, who has been awarded a place in the Swedish Polar Research Secretariat's artist program.

The participants will board Oden in Longyearbyen on Svalbard, Norway, on May 7th, but Paul Zieger from Stockholm University will already be onboard when the Oden departs Sweden on April 28th.

"It's an opportunity to calibrate and start up all the instruments so that we are prepared when the expedition starts for real. We have more than 30 instruments to be used for observing the atmosphere. After a long period of preparation, our journey finally begins, and I look forward to carrying it out along with a team of outstanding scientists from around the world," says Paul Zieger, Associate Professor of Experimental Atmospheric Science at Stockholm University.

After casting off the mooring lines at Longyearbyen on May 7th, the ship is expected to reach the ice edge in the Arctic Ocean within two days. When the Oden is positioned between northeast Greenland, northwest Svalbard, and the North Pole, the "hunt" for powerful, southerly inflows of warm and humid air that are expected to trigger the start of the melting season in the Arctic Ocean will begin. This means that the research expedition lacks a predetermined route. Instead, advanced weather forecasts will determine where the icebreaker needs to be within four to five days.

"Before the ice begins to melt, it is the most challenging to navigate in. This is one reason why there are no observations from this time of year. To more accurately predict future weather and climate, we need to study warm air inflows and their effect on Arctic snow and ice," concludes Michael Tjernström.

About the expedition

The research expedition ARTofMELT2023 (Atmospheric Rivers and the Onset of Sea Ice Melt 2023) is organized by the Swedish Polar Research Secretariat and is conducted with the icebreaker Oden leased from the Swedish Maritime Administration. The expedition involves 38 researchers from 19 organizations in 10 countries. Sweden is represented by 14 researchers from Stockholm University, Gothenburg University, Chalmers University of Technology, and Lund University. The research on board the Oden is led by Chief Scientist Michael Tjernström, Professor of Meteorology at Stockholm University, and Co-Chief Scientist Paul Zieger, Associate Professor of Experimental Atmospheric Science at Stockholm University. ARTofMELT 2023 will run from May 7th to June 15th.

Read more

• Read about the research expedition on the Swedish Polar Research Secretariat's website

Read more and watch videos from the preparations for the expedition on Stockholm University's website 

• Read about the icebreaker Oden on the Swedish Maritime Administration's website

Scientists discover rare element in exoplanet’s atmosphere

Peer-Reviewed Publication

LUND UNIVERSITY

The rare metal terbium has been found in an exoplanet’s atmosphere for the first time. The researchers at Lund University in Sweden have also developed a new method for analyzing exoplanets, making it possible to study them in more detail.

KELT-9 b is the galaxy’s hottest exoplanet, orbiting its distant star about 670 light years from Earth. The celestial body, with an average temperature of a staggering 4,000 degrees Celsius, has since its discovery in 2016 excited the world's astronomers. The new study in Astronomy & Astrophysics reveals discoveries about the scalding-hot oddball's atmosphere.

“We have developed a new method that makes it possible to obtain more detailed information. Using this, we have discovered seven elements, including the rare substance terbium, which has never before been found in any exoplanet's atmosphere”, says Nicholas Borsato, PhD student in astrophysics at Lund University.

Terbium is a rare earth metal that belongs to the so-called lanthanoids. The substance was discovered in 1843 by the Swedish chemist Carl Gustaf Mosander in the Ytterby mine in the Stockholm archipelago. The substance is very rare in nature, and 99 percent of the world's terbium production today takes place in the Bayan Obo mining district in Inner Mongolia.

“Finding terbium in an exoplanet's atmosphere is very surprising”, says Nicholas Borsato.

Most exoplanets are discovered by astronomers making measurements of how brightly stars shine. When an exoplanet passes in front of its star, the star's brightness decreases. Thanks to their advanced measurement method, the researchers have succeeded in filtering out the dominant signals in KELT-9 b's atmosphere. This opens up the possibility of finding out more about the atmospheres of other exoplanets.

“Learning more about the heavier elements helps us, among other things, to determine the age of the exoplanets and how they were formed”, explains Nicholas Borsato.

Exoplanets, or extrasolar planets, are planets that are in other solar systems than our own. The first confirmed discovery was made in 1992, of an exoplanet orbiting a neutron star. Three years later, the first exoplanet with a sun-like star was discovered. Since then, over 5,000 exoplanets have been recorded. The existence of exoplanets often raises questions about the possibility of life elsewhere in the universe.

Detecting heavy elements in the atmospheres of ultra-hot exoplanets is another step towards learning how the atmospheres of planets work. The better we get to know these planets, the greater chance we have of finding Earth 2.0 in the future”, concludes Nicholas Borsato.

Stereotypical gender roles thrive on film

Peer-Reviewed Publication

ABO AKADEMI UNIVERSITY

Popular culture plays an important role in shaping society’s perceptions and attitudes around gender roles. We are fed images and stories through television, film, music and social media that can both enhance or challenge traditional gender roles.

The film industry, which is one of the most influential media industries with an audience of billions of people around the world, plays a particularly central role in depicting gender roles.

A team of international students of the Erasmus Mundus double degree programme Engineering of Data-intensive Intelligent Software Systems (EDISS) at Åbo Akademi University recently published an article entitled “Identifying gender bias in blockbuster movies through the lens of machine learning” in the scientific journal Nature’s Journal of Humanities and Social Sciences Communications.

The student team consisted of Muhammad Junaid HarisAanchal Upreti and Melih Kurtaran. The work was advised by Sébastien Lafond and Sepinoud Azimi of the subject cluster Information Technology at Åbo Akademi University with Filip Ginter of the University of Turku as a collaborator.

In the study, students analysed the manuscripts of 34 Hollywood films in a range of genres using mathematical and machine learning techniques, looking at how gender roles are presented and how emotions are expressed by male and female characters in the films.

The results show that there are still specific patterns in the personality traits of male and female characters in films consistent with societal stereotypes. These patterns show that men on film are more aggressive, powerful, dominant and jealous, and women more loving, caring, happy and docile.

The analysis also showed that gender representation in the last 20 years has become more equal. In the years 2000–2004 only 15 per cent of characters were female, but in 2015-2019 that number increased to almost 44 per cent.

“As far as we know, this is the first time that characters’ emotional expressions in blockbuster movie productions have been studied in greater depth. Although the female roles have evolved and been allowed more prominence on screen over the years, there are still many stereotypical gender roles beneath the surface”, says Sepinoud Azimi.

Click here to read the entire research article.

EDISS is a prestigious, international and EU-funded double degree master’s programme with three partners: University of the Balearic Islands in Spain, University of L’Aquila in Italy and Mälardalen University in Sweden.

During a one-year project-based course under the EDISS study programme, teams of three to four students worked with concrete problems. Several of the projects resulted in peer-reviewed publications.

Chinese scientists develop Earth system models with clouds and ocean submesoscale eddies

Peer-Reviewed Publication

SCIENCE CHINA PRESS

Mesoscale and submesoscale ocean eddies resolved by different resolution Earth system models 

IMAGE: A AND B) SPATIAL DISTRIBUTIONS OF EDDY CENTROIDS FOR ANTICYCLONIC EDDIES (AES) (RED) AND CYCLONIC EDDIES (CES) (BLUE) WITH AMPLITUDE > .05 M, DETECTED FROM A) TS015 (PANEL A) AND TS003 (PANEL B) MODELS, AND C) HISTOGRAM OF EDDY RADIUS CONSTRUCTED FROM TS015, TS010 AND TS003 FOR THE LAST YEAR OF 3-YEAR MODEL SPINUP. RED AND BLUE BARS STAND FOR AES AND CES, RESPECTIVELY. THE RADIUS RANGE IN 50-100 KM (DENOTED BY THE RED BOX) IS ZOOMED-IN THE UPPER-RIGHT CORNER. view more 

CREDIT: ©SCIENCE CHINA PRESS

It has been a dream for Earth scientists to have a numerical model that can better represent compound multiple-scale processes in the real-world Earth system. Apart from requiring deep understanding on physics of geo-fluid motions, developing such a model demands interdisciplinary advancement in the Earth sciences and high-performance supercomputing as well as software engineering. "The successful development of Earth system models with clouds and ocean submesoscale eddies permitted is a milestone in the advancement of understanding the earth system," said Dr. Lixin Wu.

Based on the newly-developed “Sunway” heterogeneous architecture supercomputer which has a world-leading high-performance computing capability, Shaoqing Zhang, Lixin Wu and Yang Gao, a group of scientists at Ocean University of China, together with Shiming Xu, Haohuan Fu and Zhao Liu, a group of professors and engineers at Tsinghua University and National Wuxi Supercomputing Center, organize a large cross-field group of scientists and engineers to take the challenges and develop new high-resolution Earth system models.

After resolving plenties of physical and engineering issues, the large group successfully developed a series of high-resolution coupled Earth system models consisting of 12, 9 and 5 km resolution atmosphere-land models and 15, 10, 5 and 3 km resolution ocean-ice models. “These models can meet the needs of multiscale interaction studies with different computational costs," said Dr. Shaoqing Zhang.

These high-resolution models can simulate cloud cells and ocean submesoscale vortex filaments by some degree (see below). Therefore, they can bring new understanding on weather-climate mechanisms from the perspective of cross-scale interactions. "The most exciting results from these new high-resolution models are that the major weather-climate extremes in the atmosphere and ocean are captured, stressing the importance of permitted clouds and ocean submesoscale eddies in modeling tropical cyclones and eddy-mean flow interactions,” said Drs. Shiming Xu and Yang Gao.

“The new heterogeneous many-core architecture high-performance supercomputer brings new opportunities for climate modeling once the optimization of heterogeneous architecture computing is efficiently implemented. The low work consumption of heterogeneous architecture computing complies with the ‘green’ future of the world,” said Drs. Haohuan Fu and Zhao Liu.

The new high-resolution Earth system models lay the foundation for future efforts to sustain the advancement of the Earth sciences through modeling more complex biogeochemical processes and carbon cycling. “These models pave for further model development to resolve finer-scales with even higher resolution and more realistic physics. For example, based on these results, development of a nonhydrostatic, cloud and ocean submesoscale resolving Earth system model has been undergoing,” said Drs. Shaoqing Zhang and Yang Gao.

Tropical cyclones resolved by different resolution Earth system models 

See the article:

Toward Earth System Modeling with Resolved Clouds and Ocean Submesoscales on Heterogeneous Many-Core HPCs

https://doi.org/10.1093/nsr/nwad069

U.S. adults who felt discrimination at work faced increased risk of high blood pressure

Negative impacts of on-the-job discrimination on heart health had major implications, finds new study in the Journal of the American Heart Association

Peer-Reviewed Publication

AMERICAN HEART ASSOCIATION

Research Highlights:

  • U.S. adults who reported feeling highly discriminated against at work had an increased risk of developing high blood pressure than those who reported low discrimination at work.
  • Researchers suggest government and employer anti-discrimination policies and interventions may help to eliminate discrimination in the workplace.

DALLAS, April 26, 2023 — U.S. adults who reported feeling discriminated against at work had a higher risk for developing high blood pressure than those who reported low discrimination at work, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

According to the 2023 American Heart Association statistics, high blood pressure, which impacts nearly half of U.S. adults, is a major risk factor for cardiovascular disease — the leading cause of death among Americans. There is growing concern among people about the health impacts of systemic racism and discrimination on cardiovascular and other diseases, note the study authors.

“Scientists have studied the associations among systemic racism, discrimination and health consequences. However, few studies have looked specifically at the health impact of discrimination in the workplace, where adults, on average, spend more than one-third of their time,” said lead study author Jian Li, M.D., Ph.D., a professor of work and health in the Fielding School of Public Health and the School of Nursing at the University of California, Los Angeles. “To the best of our knowledge, this is the first scientific evidence indicating workplace discrimination may increase people’s long-term risk of developing high blood pressure.”

Researchers for this study and others have defined workplace discrimination as unfair conditions or unpleasant treatment at work because of personal characteristics, particularly race, sex or age. Li and colleagues analyzed information from the Midlife in the United States Study (MIDUS), which reviewed a national sample of U.S. adults across a broad range of occupations and education levels. 1,246 adults who were free of high blood pressure at the start of the study, between 2004-2006 (baseline), were followed for about 8 years, until 2013-2014. The participants were mostly white, and about half were women. About 1/3 of the participants were in each of the following age groups: younger than age 45; ages 46-55; or 56 and older. At the start of the study, most participants self-reported they were non-smokers; had no to moderate alcohol consumption (low to moderate drinking = up to two drinks per day for men and one drink per day for women; heavy drinking = more than moderate drinking); and engaged in moderate-to-high physical exercise (low = never; moderate = once a week to once a month; high = several times a week) at the start of the study.

To assess discrimination at work, participants answered survey questions about their workplace experiences, such as whether they felt they were unfairly treated, watched more closely than others or ignored more often than others. The survey also asked about frequency of ethnic, racial or sexual slurs or jokes at work, as well as if respondents felt job promotions were given fairly. Researchers calculated discrimination scores based on the participants’ responses to the survey, and participants were then divided into three groups based on perceived discrimination scores: low (score 6-7), intermediate (score 8-11) or high (score 12-30). All items and responses were weighted equally.

The analysis found:

  • Of the 1,246 people in the study, 319 reported developing high blood pressure after approximately eight years of follow-up (blood pressure noted twice: at the start of study and during follow-up period).
  • Compared to people who scored low workplace discrimination at the beginning of the study, participants with intermediate workplace discrimination exposure scores were 22% more likely to report high blood pressure during the follow-up.
  • Compared to people who scored low workplace discrimination at enrollment in the study, participants with high workplace discrimination exposure scores were 54% more likely to report high blood pressure during the follow-up.

“There are several implications from these findings,” Li said. “First, we should increase public awareness that work is an important social determinant of health. Second, in addition to traditional risk factors, stressful experiences at work due to discrimination are an emerging risk factor for high blood pressure.”

Possible solutions to eliminate workplace discrimination include organizational policies and interventions. These potential approaches, when used in tandem with stronger anti-discrimination employer policies may improve workers’ coping skills, according to the research authors.

Some limitations of this study include that participants who did not take part in the follow-up session were more likely to be non-white, have lower education levels, work in positions with lower job control, and, unfortunately, they were found to have higher hypertension prevalence. In addition, high blood pressure was self-reported as doctor-diagnosed via survey. A future study with medical examinations to measure diastolic blood pressure and systolic blood pressure may improve validity of the research findings. Furthermore, the measure of workplace discrimination in the MIDUS was generic, and a future study could explore specific, different types of workplace discrimination, such as racial-, sex- or age-related discrimination at work.

“This study adds to the growing body of science finding that discrimination of any kind may significantly increase the risk of cardiovascular disease including high blood pressure. It also underscores the importance of the American Heart Association’s commitment to addressing health equity in the workplace and among the workforce to improve individual health,” said Eduardo Sanchez, M.D., M.P.H., FAHA, FAAFP, the American Heart Association’s chief medical officer for prevention. Dr. Sanchez was not involved in this study. “As part of the Association’s overarching work to break down barriers to health equity and improve the health of all Americans, we are building strong collaborations that will drive real change in the workplace.”

Sanchez outlined several ways the Association is working toward meeting those commitments, including the release of the American Heart Association CEO Roundtable report, “Driving Health Equity in the Workplace,” and the recently launched Health Equity in the Workforce initiative with the Deloitte Health Equity Institute and the Society for Human Resource Management Foundation.

Co-authors of the study are Timothy A. Matthews, M.S.; Thomas Clausen, Ph.D.; and Reiner Rugulies, Ph.D. Authors’ disclosures are listed in the manuscript.

This study was funded by the Targeted Research Training Program of the Southern California National Institute for Occupational Safety and Health Education and Research Center, the U.S. Centers for Disease Control and Prevention, and the University of California, Los Angeles.

Studies published in the American Heart Association’s scientific journals are peer-reviewed. The statements and conclusions in each manuscript are solely those of the study authors and do not necessarily reflect the Association’s policy or position. The Association makes no representation or guarantee as to their accuracy or reliability. The Association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific Association programs and events. The Association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and biotech companies, device manufacturers and health insurance providers and the Association’s overall financial information are available here.

Additional Resources:

About the American Heart Association

The American Heart Association is a relentless force for a world of longer, healthier lives. We are dedicated to ensuring equitable health in all communities. Through collaboration with numerous organizations, and powered by millions of volunteers, we fund innovative research, advocate for the public’s health and share lifesaving resources. The Dallas-based organization has been a leading source of health information for nearly a century. Connect with us on heart.orgFacebookTwitter or by calling 1-800-AHA-USA1.

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HKU Dentistry develops core technologies using generative AI in smart manufacturing of dental crowns

Peer-Reviewed Publication

THE UNIVERSITY OF HONG KONG

Dr Hao Ding 

IMAGE: PROJECT CO-INVESTIGATOR DR HAO DING AND THE DESIGN OF A TOOTH CROWN USING GENERATIVE AI. (SMALL PHOTO) TOOTH TAILORED BY GENERATIVE AI. view more 

CREDIT: THE UNIVERSITY OF HONG KONG

Leading researchers from the Faculty of Dentistry at the University of Hong Kong (HKU) have developed a novel smart manufacturing on dental crowns by using generative artificial intelligence (AI) that leverage dental manufacturing technology.

The team, led by Dr James Tsoi, Associate Professor in Dental Materials Science collaborated with colleagues from HKU Faculty of Engineering’s Department of Computer Science to take a leap forward for the next-generation AI-designed dental prosthesis production workflow.

The researchers developed a generative AI algorithm that uses a true three-dimensional (3D) deep learning approach, producing personalised dental crowns with high accuracy that mimic the morphology and match the materials required for the biomechanics of natural teeth. Biomechanical finite element analysis revealed that by using lithium silicate, the AI-designed crown can come very close to achieving the expected lifespan of natural teeth. In contrast, the two existing methods of designing dental crowns result in crowns that are either too large or too thin, and fall short of matching the same lifespan as natural teeth.

The results have been published in leading academic journal Dental Materials in an article titled ‘Morphology and mechanical performance of dental crown designed by 3D-DCGAN’.

Currently, the Computer-Aided Design and Manufacturing (CAD/CAM) digital workflow has significantly improved dentistry but still has its challenges. From the design to the manufacture of dental prostheses, the process is labour-intensive, time-consuming, and generates health and environmental hazards during the 3D printing and milling processes. The software uses a ‘tooth library’ that contains predefined crown templates to assist in generating prosthetic designs but further adjustments are still needed by the operator to meet individual conditions.

The smart manufacturing method developed by the research team can meet the challenge and help replace the conventional approach to designing personalised dental crowns.

“We used a 3D-DCGAN (3D-Deep Convolutional Generative Adversarial Network) approach to ‘teach’ the AI algorithm ‘good’ designs by feeding the algorithm with over 600 cases of natural and healthy dentition. The algorithm improves the quality of the design through internal competition between a generator and a discriminator,” said Dr Hao Ding, a co-investigator on the project.

“During the training process, natural teeth morphological features were learned by the algorithm, so that it can design dental crowns comparable to a natural tooth — both morphologically and functionally.” Dr Ding added.

The 3D-DCGAN AI-designed crowns were compared with natural teeth and with two other conventional CAD methods of crown design methods. The results revealed that the generative AI-designed crowns had the lowest 3D discrepancy, closest cusp angle (morphological feature), and similar occlusal contacts (functional feature) as compared to natural teeth.

“This demonstrates that 3D-DCGAN could be utilised to design personalised dental crowns with high accuracy that can not only mimic both the morphology and biomechanics of natural teeth, but also operate without any additional human fine-tuning, thus saving additional costs in the production process,” said principal investigator Dr James Tsoi.

“Many AI approaches design a ‘look alike’ product, but I believe this is the first project that functionalise data-driven AI into real dental application. We hope this smart manufacturing technology will be the stepping-stone for driving Industry 4.0 in dentistry, which is vital to meet the challenges of ageing society and lack of dental personnel in Hong Kong.” He added.

Dr Tsoi said the breakthrough marks an important step towards leveraging the dental industry in Great Bay Area, which sees an annual USD3.3B revenue for producing 25-30% dental prosthesis globally, and to align with the National 14th Five-year plan in developing new forms of industrialisation and informatisation viz. smart intelligent manufacturing.

Clinical trials for using this generative AI for dental crowns are underway. The team is also working on the applicability of this tool in other dental prostheses such as bridges and dentures.

The study was supported by the General Research Fund (GRF), the Innovation and Technology Fund Mainland-Hong Kong Joint Funding Scheme (ITF-MHKJFS), and the Health and Medical Research Fund (HMRF). Its preliminary results were presented by Dr Hao Ding at the 35th Annual Scientific Meeting of the International Association of Dental Research (IADR) Southeast Asia (SEA) and it was awarded the leading IADR-SEA Research Category Award (Dental Materials and Biomaterials Category) in 2021.

The article in Dental Materials titled ‘Morphology and mechanical performance of dental crown designed by 3D-DCGAN’  published in Dental Materials, can be accessed through this link

Natural tooth (left) compared with tooth tailored by generative AI (right).

The HKU Dental Materials Science research team: (from left) co-investigator postdoctoral fellow Dr Hao Ding, principal investigator Dr James Kit Hon Tsoi, and PhD candidate Ms Yanning Chen.

CREDIT

The University of Hong Kong

Daniel Ellsberg: a Profound Voice Against the Doomsday Machine


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Photograph Source: Gotfryd, Bernard – Public Domain

The current Daniel Ellsberg Week celebrates the achievements and inspirational spirit of the most significant whistleblower of the 20th century. Daniel Ellsberg’s recent announcement of a terminal diagnosis broke my heart, but his remarkable response gave me great hope. To quote Ellsberg: “As I just told my son Robert: he’s long known (as my editor) that I work better under a deadline. It turns out that I live better under a deadline!”

Daniel Ellsberg has done just that; an avalanche of interviews and webinars have followed his announcement. And now the RootsAction Education Fund has teamed up with the Ellsberg Initiative for Peace and Democracy to co-sponsor Daniel Ellsberg Week, April 24-30, to celebrate his life’s work and “to honor peacemaking and whistleblowing.”

Known as the insider who blew the whistle on U.S. government lying about the Vietnam War, Ellsberg’s high level military planning experience began earlier. Ellsberg was a nuclear war planner during the 1950s and ’60s. For decades he has put himself on the line to oppose those evil plans; writing, speaking, standing up and sitting-in against the threat of nuclear annihilation. Ellsberg has been hauled off to jail for civil disobedience against war over 80 times. Here he offers chilling clarity about “the nuclear war planners, of which I was one, who have written plans to kill billions of people,” calling it “a conspiracy to commit omnicide, near omnicide, the death of everyone.” He asks us, “Can humanity survive the nuclear era? We don’t know. I choose to act as if we have a chance.”

This quote is from one of several eye-opening podcasts being released this week (which I directed in partnership with the RootsAction Education Fund), enabling people to hear Ellsberg directly. In these half dozen two-to-three-minute animated musings, Daniel Ellsberg offers up a succinct analysis of the calamity posed by nuclear weapons and a possible way to reduce their risk. You can watch and listen here.

When Daniel Ellsberg leaked the Pentagon Papers in 1971, Henry Kissinger (then President Nixon’s national security advisor) called him “the most dangerous man in America.” But those closely held secrets of the war in Vietnam were less explosive than the nuclear secrets that Ellsberg held in his safe. Then a top strategist for the Defense Department, he had been party to plans for a nuclear holocaust. After being buried for safekeeping, those documents disappeared in a hurricane that literally blew away his secrets, but that didn’t dampen Ellsberg’s desire to share what he knew.

At 92, with mind sharp as ever, Ellsberg remains an undisputed expert on “national security.” In this unusual illustrated podcast, he shares his unvarnished thoughts about the threat of nuclear annihilation and how it might be defused.

Can we simply ignore the reality of the world’s largest nuclear arsenals on hair-trigger alert — amid escalation of a new cold war with heightened nuclear dangers? Indeed, the U.S. just enacted its biggest military budget in history, with unprecedented investment in weapons of mass destruction and their deployment.

We ignore this impending disaster and its impassioned opponent, Daniel Ellsberg, at our own peril.

Here’s a chance to honor him by listening and heeding his words.

Judith Ehrlich co-directed and produced “The Most Dangerous Man in America, Daniel Ellsberg and the Pentagon Papers,” which was nominated for an Oscar and Emmy and won the Peabody Award. Her recent film, “The Boys Who Said NO!” features Daniel Ellsberg, Joan Baez and a cast of war resisters who chose prison over killing in the Vietnam War. Ehrlich is currently in production on “The Mouse that Roared,” a film on the evolution of the Internet poetically explored through Icelandic MP/“poetician,” single mother, defender of whistleblowers and Internet pioneer, Birgitta Jónsdóttir. To watch the Oscar-nominated film on Daniel Ellsberg, please go to: www.mostdangerousman.org. To host a screening of “The Boys Who Said NO!” see here, and to read Ellsberg’s 2017 gripping expose “The Doomsday Machine: Confessions of a Nuclear War Planner” see: https://www.ellsberg.net.