Sunday, June 28, 2026

 

New design approach may help slash the price of ultra-durable concrete




Penn State
Ultra-high-performance concrete research 

image: 

A team of engineers at Penn State is researching approaches to make ultra-high-performance more affordable. They tested their mixtures using a series of lab experiments, including a unique device that can effectively measure the tensile strength of concrete under stress.

view more 

Credit: Poornima Tomy / Penn State





UNIVERSITY PARK, Pa. — Concrete, although the most common building material in the world, is brittle and can easily crack under tension. Ultra-high-performance concrete (UHPC) is a special class of concrete known for its dense structure and extreme durability. This class uses internal metallic fibers to flex and resist cracking — the downside being these fibers can lead the material to cost up to 30 times more than traditional concrete. A team of researchers, led by engineers from Penn State, is laying the foundation to help builders get more bang for their buck when using this specialized compound.

The team used a series of tests to measure the physical strength and ductility, or ability to flex and bend without cracking, of different UHPC mixtures, including experimental types reinforced with both metallic and non-metallic fibers. Testing identified several key characteristics that can be optimized to reduce the material’s price — cutting costs by up to 75% — while maintaining its remarkable strength, ductility and durability. The team developed a new design approach based on their assessments, which they said could help material producers, infrastructure owners and construction companies around the globe not just save money, but develop stronger and more environmentally friendly concrete. They published their work in Cement and Concrete Composites.

UHPC has become critical for building large, durable structures like bridges, high-rise buildings or coastal infrastructure like floodgates due to its high strength, ductility and exceptional durability, according to study co-author Farshad Rajabipour, the John and Harriette Shaw Professor of Civil and Environmental Engineering and head of the Department of Civil and Environmental Engineering at Penn State. Specifically, Rajabipour said UHPC is the key to accelerated bridge construction, which helps streamline bridge building and repairs that used to take months to just days or weeks.

“Elements of the bridge are prebuilt in a factory, brought to a site and then put together almost like Lego pieces,” Rajabipour explained. “The main portions of the bridge are built out of traditional concrete, but the grout that bonds each piece and holds them in place is UHPC. It’s not meant to replace traditional concrete, but to instead support high-strength applications.”

The material’s strength and ductility come from within. Thousands of tiny steel fibers are encased inside a larger matrix of cement, water, aggregates and additives, with each fiber measuring only 13 millimeters, about half an inch long, and 0.2 millimeters, or less than eight thousandths of an inch thick. By mechanically latching onto the cement matrix they are encased in, they form a material that is flexible in the face of extreme tension.

However, Rajabipour said these fibers are the major culprit behind the price spike. Despite only making up about 2% of the material’s total volume, they’re responsible for about 70% of the cost. Additionally, UHPC is commercially sold as pre-bagged, proprietary mixtures, further increasing the price of use. According to Rajabipour, the key to making the material more commercially accessible and affordable is optimizing the fibers.

To do this, the team produced 15 different mixtures of UHPC. Nine of the 15 mixtures used metallic fibers, employing different concentrations and designs to see if the same performance could be obtained for less material and, in turn, a lower price.

“We tried different lengths, widths and shapes of fiber — indenting them, twisting them, adding tiny hooks to help them better latch onto the cement matrix,” Rajabipour said. “The thought is that if we can get the same or better performance using less material, we can massively reduce the price.”

The team also tested six mixtures using non-metallic fibers made of fibrillated, or very thin, glass strands; a type of stone known as basalt; as well as polymer reinforced with glass or carbon fibers. Although these materials are not as strong as traditional steel fibers, Rajabipour said that identifying a non-metallic fiber that can provide similar performance could be a major leap in reducing the overall price of UHPC.

The individual samples were then subjected to a series of tests that the team developed to assess key mechanical characteristics of the different concrete mixtures. They evaluated each mixture’s flowability in liquid form, which Rajabipour said is important to understand when considering use for rapid, high-quality construction projects; compressive strength, or durability under forces pushing on the material; tensile strength, or durability under forces pulling the material; ductility; and bond strength, or the force it took for the internal fibers to come disconnected from the cement matrix.

The team observed that two of the metallic fibers tested — microsteel and striated steel — were able to maintain their performance, even when the total fiber volume was cut in half.

Additionally, the team identified which characteristics have the biggest impact on the UHPC’s performance. Fibers with higher length-to-diameter ratios exhibit much improved tensile performance. The team reported that engineering the bond so that the fibers pull out from the concrete before snapping under stress is critical to maintaining the strong performance. They also noted that although commercial non-metallic fibers still do not perform like steel fibers, better designs could produce fibers that offer metal-like performance for a fraction of the cost.

“Because of these tests, we have clear, number-based data on what characteristics should be optimized to save money, while not impacting performance,” Rajabipour said. “We knew that all these factors mattered — the volume fraction of fibers in the material matters, the total number of fibers matters and the bonding strength of the fibers matters — but we didn’t have clear quantitative information on how critical they each were.”

Going forward, the team plans to conduct further research on different fiber makeups, explore new non-metallic fibers and optimize existing manufacturing approaches. Additionally, the researchers plan to continue studying different opportunities to reduce the carbon dioxide that is released during UHPC manufacturing, greatly improving the sustainability of this material.

“We’ve shown pathways so that concrete producers can reliably make UHPC, instead of it being limited to a few proprietary formulations,” Rajabipour said. “The fibers are not only the biggest contributor to cost; they’re also the biggest contributor to emissions. We are not only presenting a pathway to reducing the cost of this material, but reducing their environmental impact, as well.”

Rajabipour holds additional affiliations with the Larson Transportation Institute and the Materials Research Institute. Other co-authors on the work include Rajabipour’s doctoral candidate advisees: Abdullah Al Moman, a structural design engineer at Dutchland who received his doctorate in civil engineering from Penn State; Deepika Sundar, research scientist at CalPortland who received her doctorate in civil engineering from Penn State; and Amir Alarab, structural engineering at AECOM, who earned his doctorate in civil engineering from Penn State.

Additional co-authors include Shaohua Chu, assistant research professor of civil engineering; and Jovan Tatar, associate professor of civil, construction and environmental engineering at the University of Delaware.

This research was supported by the U.S. Department of Transportation and the Pennsylvania Department of Transportation.

At Penn State, researchers are solving real problems that impact the health, safety and quality of life of people across the commonwealth, the nation and around the world.

For decades, federal support for research has fueled innovation that makes our country safer, our industries more competitive and our economy stronger. Recent federal funding cuts threaten this progress.

Learn more about the implications of federal funding cuts to our future at Research or Regress.  

Concrete fiber microscopy 

Above is a look at several different types of internal fibers highly magnified through a microscope — including fibrillated basalt fibers tightly bundled together (a), a fiber reinforced polymer, with internal glass fibers glued together with resin (b), the magnified end of a hook steel fiber (c) and a single striated steel fiber (d). These internal fibers are the key to giving ultra-high-performance concrete its strength.

Credit

Provided by Farshad Rajabipour


 

Plastic bottles could find new life in batteries as graphite



Penn State





UNIVERSITY PARK, Pa. — A plastic bottle tossed into a recycling bin could one day help power an electric vehicle, smartphone or renewable energy storage system, according to a team of Penn State researchers.

In a new study, researchers converted waste polyethylene terephthalate, or PET, into highly ordered synthetic graphite, a crystalline form of carbon. The formed graphite exhibited large, well-ordered crystallites — or microscopic regions of well-aligned carbon layers — indicating a highly organized crystal structure. These properties exceeded those of commercial natural graphite samples, indicating that the PET-derived material had a more ordered crystal structure. Such structural ordering is a key indicator of suitability for high‑quality anode materials when compared to natural graphite commonly used as a benchmark in battery research.

The findings, published in Diamond and Related Materials, suggest that a common waste material could become a valuable source of battery-grade carbon.

"Most people think of a plastic bottle as waste once they're done using it," said Shakshi Sekar, lead author of the study and a doctoral student in Penn State's John and Willie Leone Family Department of Energy and Mineral Engineering. "Our work shows that the same material can become a valuable resource for producing graphite, which is essential for modern battery technologies."

Classified as a critical mineral by the U.S. Department of Energy, graphite is an integral component of lithium-ion batteries, serving as the anode material that stores and releases electrical charges. As demand for electric vehicles, consumer electronics and grid-scale energy storage systems continue to grow, so does demand for battery-grade graphite.

At the same time, PET remains one of the most widely used plastics in the world, according to the National Association for PET Container Resources. Although many consumers place plastic bottles in recycling bins, much of that material is ultimately discarded, downcycled into lower-value products or sent to landfills.

The research team said they saw an opportunity to address both challenges.

By combining shredded PET plastic with small amounts of graphene oxide and heating the material through a carefully controlled thermal process, the team was able to reorganize carbon atoms within the plastic into highly ordered graphitic structures.

"We're not simply finding a use for waste plastic," Sekar said. "We're creating a valuable material that could help support the growing demand for batteries and clean energy technologies."

The researchers found that adding just 2.5% graphene oxide by weight produced the highest-quality graphite. Under those conditions, the material developed crystallite dimensions that exceeded those associated with natural graphite, indicating an exceptional degree of structural order.

According to the researchers, oxygen-containing functional groups located along the edges of graphene oxide sheets help initiate and promote lateral graphite crystal growth. The exposed graphene surfaces act as templates that guide carbon atoms into highly organized stacked arrangements during graphitization, the process of transforming carbon into graphite.

The team's approach differs from many previous methods used to produce synthetic graphite. Common graphitization techniques often rely on metal catalysts such as iron, nickel or cobalt, which can leave behind impurities that require additional chemical purification steps to be removed.

Instead, these researchers used graphene-based additives that promote graphitization without introducing metallic contaminants.

"By avoiding metal catalysts, we can produce cleaner graphite while reducing chemical use and waste generation," Sekar said.

Eliminating catalyst removal steps could simplify future manufacturing and reduce the environmental footprint associated with producing battery materials, the researchers said.

While additional work is needed to evaluate large-scale production and battery performance, the study demonstrates a promising pathway for transforming one of the world's most common waste streams into a high-value energy storage material.

The findings also point to a broader shift in how plastic waste could be viewed in the future, Sekar noted.

"If waste plastic can become a feedstock for advanced energy materials, it changes how we think about recycling," Sekar said. "Instead of viewing plastic as a disposal problem, we can see it as a resource that helps support clean energy technologies."

Other authors on the study include Randy Vander Wal, professor of energy and mineral engineering at Penn State and faculty member in Penn State’s Institute of Energy and the Environment.

The research was supported by the U.S. National Science Foundation.

13-second eye test may help predict recovery of consciousness after severe brain injury


A simple bedside eye test may help predict recovery of consciousness in patients with severe brain injuries, according to new research presented at the European Academy of Neurology (EAN) Congress 2026



Beyond





(Geneva, Switzerland, Sunday, 28 June 2026) A simple bedside eye test may help predict recovery of consciousness in patients with severe brain injuries, according to new research presented at the European Academy of Neurology (EAN) Congress 2026.1

 

The study found that a previously overlooked phase of the pupil response to light, known as the late light-off response (LOR), predicted improvements in consciousness seven days later in patients with acute brain injury. In contrast, standard pupil measurements already widely used in intensive care units (ICUs), including the Neurological Pupil Index (NPi) and pupillary light reflex (PLR) latency, did not predict later gains in consciousness.

 

Predicting whether a patient will recover consciousness after a severe brain injury remains one of the greatest challenges in intensive care.2 While automated pupillometry is already widely used in ICUs to assess brain function, existing measures mainly capture the pupil’s immediate reaction to light and offer limited insight into longer-term recovery.

 

Researchers from Copenhagen University Hospital Rigshospitalet and the Danish Technical University investigated whether a later phase of the pupil response, occurring after the eye reacts to light, could provide additional insight into recovery potential in patients with acute disorders of consciousness. The study included 250 patients with impaired consciousness following traumatic and non-traumatic brain injury, alongside 30 age- and sex-matched healthy controls. Patients underwent daily automated pupillometry and neurological assessments for up to 20 days in the ICU.

 

The research found that late LOR latency independently predicted improvement in consciousness seven days later, even after accounting for baseline neurological status, time since injury, sedation and injury type. Notably, the measure was not associated with patients’ level of responsiveness on the same day, suggesting it may reveal recovery potential not apparent during routine bedside assessment.

 

Dr Poul Laigaard, lead author from Copenhagen University Hospital Rigshospitalet, commented, “Current tests of pupillary function tell us how the brain is responding in the moment, but the late light-off response may provide clues about the brain’s potential for recovery. This could help us better understand which patients may improve in the days ahead.”

 

The relationship appeared strongest in patients who were not receiving sedative medication and in those with anoxic–ischaemic brain injury, a condition in which the brain is deprived of oxygen and blood flow.³ However, researchers caution that these subgroup findings were exploratory and require confirmation in larger studies.

 

Professor Daniel Kondziella, senior author of the study, added, “We believe this is an important observation that deserves further investigation. Larger, multicentre studies are needed to determine whether this approach could be used routinely for bedside monitoring and prognosis.”

 

Because the technology required is already available in many ICUs, Dr Laigaard explained the approach could be relatively easy to implement if validated in future studies.

 

“The light-off response is measured using a handheld automated pupillometer in much the same way as current pupil measurements. The entire assessment takes only 13 seconds per eye, making it a fast and practical bedside tool that could potentially be integrated into routine ICU care.”

 

ENDS


Notes to Editors:

Press Enquiries:

A reference to the EAN Congress must be included when communicating the information within this press release.

For further information or to speak to an expert, please contact the press team at press@ean.org.


About the Expert:

Dr Poul P. Laigaard, MD from the University of Copenhagen since 2020 is an aspiring neurologist and is currently pursuing a PhD under the supervision of Professor Daniel Kondziella at Copenhagen University Hospital, Rigshospitalet, focusing on the diagnostic and prognostic value of pupillary dynamics in disorders of consciousness.


About the EAN:

The EAN is a non-profit, independent organisation representing more than 45,000 members, as well as 48 European national societies. As a medical society we promote excellence in the practice of general neurology throughout Europe, leading to improved patient care.

We also aim to keep Europe at the forefront of neurological research and maintain its position as one of the world’s leading scientific hotspots in neurology.

Learn more: ean.org  


References:

  1. Laigaard, P., Stückler, S., Eigenbrodt, A. et al. (2026). Pupillary light-off latency predicts 7-day improvement in consciousness in patients with acute disorders of consciousness. Abstract A-26-17842. Presented at the 12th EAN Congress (Geneva, Switzerland).
  2. Edlow, B.L., Claassen, J., Schiff, N.D., Greer, D.M. (2021). Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies. Nature Reviews Neurology; 17(3):135–156.
  3. Messina, Z., Shapshak, A.H., Mills, R. (2023). Anoxic Encephalopathy. StatPearls. NCBI. Available at: https://www.ncbi.nlm.nih.gov/books/NBK539833/.

Multiple sclerosis impacts daily life far beyond its physical symptoms, new study finds



Multiple sclerosis (MS) can have a substantial impact on many aspects of life beyond physical health, with 51% of people reporting that the disease affects their social life and 48% reporting that it affects their work.




Beyond

Figure 1 

image: 

Impact of multiple sclerosis (MS) on social determinants of health (SDH). Left panel: Frequency of participants reporting impact of MS in the four domains. Numbers on connecting lines indicate participants reporting impact in both domains. Right panel: Distribution of participants according to the number of domains impacted by MS (0–4).

view more 

Credit: European Academy of Neurology





(Geneva, Switzerland, Sunday, 28 June 2026) Multiple sclerosis (MS) can have a substantial impact on many aspects of life beyond physical health, with 51% of people reporting that the disease affects their social life and 48% reporting that it affects their work, according to new research presented at the European Academy of Neurology (EAN) Congress 2026.¹

Although the physical effects of MS are well recognised, less is known about how the disease affects broader social determinants of health. Previous studies have often focused on individual areas, such as employment or financial wellbeing, in isolation. However, little research has explored how multiple social determinants are affected simultaneously and how they interact.

To explore these wider impacts, researchers from Italy conducted the SocialMS study, a nationwide questionnaire-based study involving 1,039 adults with MS receiving care at 68 MS centres across the country. Participants were asked about the impact of MS on four key social determinants of health: education, work, financial resources and social life.

Social life emerged as the most commonly affected domain, with 51% of participants reporting an impact, followed by work (48%), financial resources (34%) and education (19%).

The study also found that the four domains were closely interconnected (Figure 1). Additional analyses conducted by the researchers identified the strongest associations between work and social life and between work and financial resources.

People experiencing financial difficulties, being out of work or retired early, additional health conditions or greater levels of disability were more likely to report impacts across multiple domains. Economic strain and disability were associated with all secondary outcomes examined in the study.

Lead author Dr Marta Ponzano of Link Campus University, Rome, Italy, said: "Our data show that multiple domains of life are substantially affected by MS beyond physical health, particularly social life and work. Importantly, the greatest burden falls on individuals who are socioeconomically and medically more vulnerable, with disability emerging as a key driver of disadvantage.”

"Taken together, these findings highlight the need for a more comprehensive, person-centred approach to MS care. We do not treat only MS, but the person living with MS. That means recognising and addressing the impact of the disease on daily functioning, employment, social participation and overall wellbeing, not just its physical symptoms," she explained.

Almost 90% of participants reported receiving some form of social support. Family members were the major source of both practical and emotional support, with 61% receiving practical support from family and 76% receiving emotional support. Friends were also an important source of emotional support, cited by 43% of participants.

Support also came from less traditional sources. More than 16% of participants reported receiving emotional support and companionship from pets, while almost 12% reported receiving emotional support from colleagues.

Despite the importance of these support networks, the study also found that MS can place strain on relationships. Among participants whose social life was affected by the disease, 54% reported impacts on relationships with partners and 46% reported impacts on friendships.

Dr Ponzano explained: "These two findings, which may appear contradictory, actually highlight the dual nature of this domain. Family and friends are often an important source of support for people living with MS, yet the disease can also place strain on those same relationships."

Participants reporting a greater MS-related burden – and therefore greater need – were also more likely to receive support.

"While this could represent an encouraging finding, future studies should investigate whether support is activated in response to higher levels of need or provided proactively," said Dr Ponzano. "A preventive model rather than a reactive one may be more beneficial for individuals with MS."

Looking ahead, Dr Ponzano emphasised the need for broader support for people living with MS: "Our findings highlight that the impact of MS extends beyond physical health, affecting social life, employment, financial resources and education. For healthcare systems and policymakers, these results underscore the value of multidisciplinary support services and policies aimed at reducing the broader social and economic burden of the disease.”

“Routine assessment of these wider impacts, together with closer coordination between healthcare and social support services, may help identify unmet needs early and reduce inequalities among people living with MS," she concluded.

 

ENDS


Notes to Editors:

Press Enquiries:

A reference to the EAN Congress must be included when communicating the information within this press release.

For further information or to speak to an expert, please contact the press team at press@ean.org.


About the Expert:

Dr Marta Ponzano is an Assistant Professor of Medical Statistics at the Department of Life Sciences, Health and Health Professions at Link Campus University, Rome, Italy.

She earned a bachelor’s degree in mathematical Statistics and Data Management from the University of Genoa and a master’s degree in Biostatistics from the University of Milano-Bicocca, with a research period in Boston at the Harvard T.H. Chan School of Public Health. She completed an International PhD in Health Sciences at the University of Genoa, conducting part of her research at Harvard University.

Her research activity focuses primarily on multiple sclerosis, addressing multidisciplinary topics, with main focus on health inequalities, and is carried out through extensive international collaborations.


About the EAN:

The EAN is a non-profit, independent organisation representing more than 45,000 members, as well as 48 European national societies. As a medical society we promote excellence in the practice of general neurology throughout Europe, leading to improved patient care.

We also aim to keep Europe at the forefront of neurological research and maintain its position as one of the world’s leading scientific hotspots in neurology.

Learn more: ean.org  


References:

  1. Ponzano, M., Signori, A., Landi, D., et al. (2026). Exploring the impact of multiple sclerosis on social determinants of health: results from the SocialMS study. Abstract A-26-16674. Presented at the 12th EAN Congress (Geneva, Switzerland).

 

A “copper economy” helps fungi and bacteria build better biofilms



Scientists have discovered that two common human pathogens can work together by managing copper in their shared environment - a finding that could open new ways to break down stubborn mixed biofilms



University of Exeter

Candida albicans and Staphylococcus aureus mixed biofilm. 

image: 

Candida albicans and Staphylococcus aureus mixed biofilm. 

view more 

Credit: Christian Hacker, Orlando Ross and Seána Duggan, University of Exeter





Scientists have discovered that two common human pathogens can work together by managing copper in their shared environment - a finding that could open new ways to break down stubborn mixed biofilms.

The fungus Candida albicans and the bacterium Staphylococcus aureus are both major causes of human infection. They are also found together in complex infections, including wounds, bloodstream infections and infections linked to medical devices.

When microbes form biofilms, they grow as surface-attached communities that can be difficult to treat. Mixed fungal-bacterial biofilms are especially challenging because different organisms can protect or support one another, making infections harder to clear.

Now, researchers led by Dr Seána Duggan, from the University of Exeter’s MRC Centre for Medical Mycology, have discovered that copper plays a central role in this fungal-bacterial partnership. The study, supported by the NIHR Exeter Biomedical Research Centre,  reveals what the team describes as a microbial “copper economy”, in which the fungus and bacterium handle copper in different but complementary ways.

Dr Duggan said: “We usually think about copper as something that can kill microbes, because high levels are toxic. Our study reveals something more nuanced. In these mixed biofilms, copper appears to act almost like a shared currency that helps two very different pathogens cooperate. When that copper balance is disturbed, the partnership collapses. That gives us a potential new way to think about targeting infections that are difficult to treat because they involve more than one type of microbe.”

The team grew C. albicans and S. aureus together under laboratory conditions designed to mimic the human body. They found that the two species formed larger and more active biofilms than either microbe alone. Protein analyses showed that C. albicans increased proteins involved in copper uptake, while S. aureus increased proteins linked to copper export and copper stress protection.

Changing copper availability disrupted this cooperation. Both excess copper and copper limitation weakened the mixed biofilm, showing that the community depends on a finely balanced copper environment.

Dr Duggan said: “The most striking thing was that the mixed biofilm was much more sensitive to copper disruption than either organism alone. That tells us we are not just looking at the biology of one pathogen or the other. We are looking at the biology of the relationship between them.”

The study also showed that copper shaped the physical structure of the biofilm, and early tests suggest that copper-based approaches could help break these microbial communities down.

Dr Duggan said: “Mixed infections are a major clinical challenge, yet we still know relatively little about the molecular mechanisms inside these communities. Our work shows that micronutrients such as copper might dictate whether pathogens compete, cooperate, or become harder to treat. If we can identify the conditions that make these microbial partnerships fail, we may be able to design better ways to break them apart.”

The study highlights the importance of looking beyond single-pathogen infections and considering the cooperative behaviours that can emerge when fungi and bacteria grow together.

The paper is titled “Copper Driven Mutualism of Candida albicans and Staphylococcus aureus Interkingdom Biofilms” and is published in Microbiology.