Tuesday, April 28, 2026

 

New insights into ancient Gondwana fossil from Antarctica





Flinders University
Life reconstruction 

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Life reconstruction of Devonian tetrapodomorph fish Koharalepis jarviki. Original painting by Honours student and palaeoartist Thomas Turner.

 

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Credit: Flinders University





Flinders University researchers have taken a revealing look inside the head of one of the first animals to crawl from the water to live on land more than 380 million years ago.  

Using high-tech neutron imaging, they scanned the skull and braincase of the only known specimen of Koharalepis jarviki, a large fossil fish found in freshwater rivers in the vast Lashly Mountains region of Antarctica which lived during the Devonian Period or 'Age of Fishes'.

“This precious fossil belongs to a group called the Canowindridae which highlights the ancient links between Australia and Antarctica,” says Flinders University Research Fellow Dr Alice Clement, coauthor of a new article in Frontiers in Ecology and Evolution

“It is important to study such specimens from the Devonian Age of Fishes when the waters teemed with predatory lobe-finned fish like this that are closely related to land animals (tetrapods),” says Dr Clement, from the College of Science and Engineering.

Koharalepis is a member of the Canowindrid family, a group that lived in East Gondwana and have fossils found today across Australia and Antarctica. It is an ancestor of the first land animals or four-limbed vertebrate tetrapods.

Lead author of the new study, Corinne Mensforth, a PhD candidate from the Flinders Palaeontology Lab, says: “We chose to focus on Koharalepis as it is the only fossil in the entire family to preserve the internal bones of the skull, which gives us valuable insights into its braincase and neuroanatomy.”

“We found evidence that the brain of Koharalepis was similar to those of the fishes that straddle the vertebrate water-to-land transition.

“We also found adaptations to life near the surface of the water, including openings in the top of the skull for additional air intake and an organ within the brain that detects light and circadian rhythms.

Koharalepis which grew to about 1 metre was an ambush predator that preyed on other smaller animals in their environment, and with relatively small eyes it must have relied heavily on its other senses to capture its prey.”

Another coauthor of the latest study, Flinders University Emeritus Professor John Long, was part of earlier research describing Koharalepis in 1992.  

Professor Long says the new data generated by modern non-destructive imaging techniques describe the internal skeleton of the skull, shoulder girdle and part of the backbone.

“This has enabled us to understand some of the behaviour, adaptations and relationships of Koharalepis to its environment and to the other tetrapod-like fishes – and how fish first left the water to live on land approximately 385 million years ago,” he says.

The article, New data on the sarcopterygian Koharalepis jarviki (Tetrapodomorpha; Canowindridae) from the Late Devonian of Antarctica, revealed via synchrotron and neutron tomography (2026) by Corinne L Mensforth, John A Long, Joseph J Bevitt (Australian Centre for Neutron Scattering, ANSTO) and Alice M Clement has been in Frontiers in Ecology and Evolution. DOI: 10.3389/fevo.2026.1765271.

Acknowledgements: This work was supported by the Australian Research Council (DP 200103398), with thanks to  Dr Matthew McCurry (Australian Museum) for specimen loan and Anton Maksimenko for assistance with synchrotron scanning (Australian Nuclear Science and Technology Organisation).

Photos, illustrations and captions:https://drive.google.com/drive/folders/1MwSdOSS0DYhpQuseE-S6MRlHC6yphEOq

 

Yes, that late-night snacking is probably messing up your gut



The one-two punch of stress and nighttime eating may lead to toilet trouble



Digestive Disease Week





BETHESDA, MD (April 23, 2026) — It’s well known that chronic stress can disrupt bowel function, sending people running to the bathroom or making them constipated. New research to be presented at Digestive Disease Week® (DDW) 2026 suggests that eating late at night amplifies these effects, with implications for both digestive health and the gut microbiome.

“It’s not just what you eat, but when you eat it,” said Harika Dadigiri, MD, resident physician at New York Medical College at Saint Mary’s and Saint Clare’s Hospital, and the study’s lead author. “And when we’re already under stress, that timing may deliver a ‘double hit’ to gut health.”

Researchers analyzed data from more than 11,000 participants in the National Health and Nutrition Examination Survey to examine links between chronic stress, late-night eating and bowel dysfunction. Individuals with a high allostatic load score — the cumulative physiological stress as reflected in body mass index (BMI), cholesterol level, and blood pressure — who also reported eating more than 25% of daily calories after 9 p.m. were 1.7 times more likely to experience constipation and diarrhea than those with lower scores who did not eat late at night.

Similarly, data from more than 4,000 participants in the American Gut Project found that people with both high stress levels and late-night eating habits were 2.5 times more likely to report bowel problems. These individuals had significantly lower gut microbiome diversity, suggesting that meal timing might magnify the impact of stress on the microbiome via the gut-brain axis — the two-way communication system involving nerves, hormones and gut bacteria.

The study was observational, so the findings highlight associations rather than cause-and-effect. Further research is needed to better understand how stress, eating patterns and gut health are connected. Still, the results underscore growing awareness of chrononutrition: how the body’s circadian rhythm impacts the way it processes food.

Dr. Dadigiri is sympathetic to those who reach for late-night snacks after long, demanding days, and as a medical resident, she counts herself among them.

"I'm not the ice cream police,” Dr. Dadigiri said. “Everyone should eat their ice cream — maybe preferably earlier in the day. Small, consistent habits, like maintaining a structured meal routine, may help promote more regular eating patterns and support digestive function over time.”

DDW Presentation Details

Dr. Dadigiri will present data from the study, “Beyond sleep alone: How stress and late-night eating disrupt bowel habits and gut microbiome diversity, a multi-cohort study,” abstract Mo1769, at 12:30 p.m. CDT,  Monday, May 4. For more information about featured studies and a schedule of availability for featured researchers, please visit www.ddw.org/press

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Digestive Disease Week® (DDW) is the largest international gathering of physicians, researchers, and academics in the fields of gastroenterology, hepatology, endoscopy, and gastrointestinal surgery. Jointly sponsored by the American Association for the Study of Liver Diseases (AASLD), the American Gastroenterological Association (AGA), the American Society for Gastrointestinal Endoscopy (ASGE) and the Society for Surgery of the Alimentary Tract (SSAT), DDW is an in-person and online meeting from May 2-5, 2026. The meeting showcases more than 6,000 abstracts and more than 1,000 lectures on the latest advances in GI research, medicine and technology. More information can be found at www.ddw.org

 

The CIRTESU at the Universitat Jaume I develops an experimental modular robotic fish prototype for aquaculture use that reduces fish stress



Experimental results have confirmed the feasibility of UJIFISH-I, demonstrating high manoeuvrability and reliable target detection accuracy



Universitat Jaume I

A experimental modular robotic fish prototype for aquaculture use that reduces fish stress 

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The Centre for Research in Robotics and Underwater Technologies (CIRTESU) at the Universitat Jaume I in Castelló has developed an experimental modular, bio-inspired robotic fish prototype (UJIFISH) for inspection, hybrid teleoperation and sensor deployment in aquaculture. Its innovation lies in a functional design that eliminates stress factors such as propellers and high-intensity lighting, while maintaining high standards of modularity and interoperability.

The biomimetic platform has been designed to minimise environmental disturbance and reduce stress in fish by using bio-inspired undulatory propulsion, which lowers mechanical noise, hydraulic turbulence and physical disruption. The system is equipped with a modular sensing system for real-time data acquisition and image transmission, with hybrid communication capabilities via cable or acoustic modem. It features a panoramic vision system with a 180-degree field of view and can operate at depths of up to 20 metres, with remote control ranges of up to 150 metres vertically and 500 metres horizontally.

UJIFISH incorporates sensors for continuous measurement of water temperature and depth, with the option to integrate additional sensors to monitor parameters such as salinity, pH, dissolved oxygen and gases. It enables direct inspection of net structures and monitoring of environmental conditions around fish, and includes a deployment system for transporting and releasing auxiliary components at specific locations. Its geometry and movement have been scaled to match adult fish, producing smoother hydrodynamic profiles and reducing acoustic disturbance.

Experimental results have confirmed the prototype’s functional viability, demonstrating high manoeuvrability and reliable target detection accuracy in controlled tests involving net inspection, teleoperation, data collection and sensor deployment. According to the research team, the flexibility of UJIFISH-I is essential in aquaculture environments, where monitoring requirements and technological constraints vary depending on species, infrastructure and environmental conditions.

UJIFISH-I represents a significant step forward in precision aquaculture and underwater robotics, supporting environmentally responsible operations and reducing the need for human intervention in hazardous underwater environments. Future developments will focus on improving autonomy, endurance and sensing capabilities, including the integration of advanced sensors and an artificial swim bladder system for active buoyancy control, enabling greater depth ranges and improved energy efficiency.

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Credit: CIRTESU Universitat Jaume I of Castellón





The Centre for Research in Robotics and Underwater Technologies (CIRTESU) at the Universitat Jaume I in Castelló has developed an experimental modular, bio-inspired robotic fish prototype (UJIFISH) for inspection, hybrid teleoperation and sensor deployment in aquaculture. Its innovation lies in a functional design that eliminates stress factors such as propellers and high-intensity lighting, while maintaining high standards of modularity and interoperability.

The biomimetic platform has been designed to minimise environmental disturbance and reduce stress in fish by using bio-inspired undulatory propulsion, which lowers mechanical noise, hydraulic turbulence and physical disruption. The system is equipped with a modular sensing system for real-time data acquisition and image transmission, with hybrid communication capabilities via cable or acoustic modem. It features a panoramic vision system with a 180-degree field of view and can operate at depths of up to 20 metres, with remote control ranges of up to 150 metres vertically and 500 metres horizontally.

UJIFISH incorporates sensors for continuous measurement of water temperature and depth, with the option to integrate additional sensors to monitor parameters such as salinity, pH, dissolved oxygen and gases. It enables direct inspection of net structures and monitoring of environmental conditions around fish, and includes a deployment system for transporting and releasing auxiliary components at specific locations. Its geometry and movement have been scaled to match adult fish, producing smoother hydrodynamic profiles and reducing acoustic disturbance.

Experimental results have confirmed the prototype’s functional viability, demonstrating high manoeuvrability and reliable target detection accuracy in controlled tests involving net inspection, teleoperation, data collection and sensor deployment. According to the research team, the flexibility of UJIFISH-I is essential in aquaculture environments, where monitoring requirements and technological constraints vary depending on species, infrastructure and environmental conditions.

UJIFISH-I represents a significant step forward in precision aquaculture and underwater robotics, supporting environmentally responsible operations and reducing the need for human intervention in hazardous underwater environments. Future developments will focus on improving autonomy, endurance and sensing capabilities, including the integration of advanced sensors and an artificial swim bladder system for active buoyancy control, enabling greater depth ranges and improved energy efficiency.

The project is part of the ThinkInAzul programme, supported by the Spanish Ministry of Science and Innovation, the European Union NextGenerationEU funds and the Generalitat Valenciana. The prototype has been tested at CIRTESU’s water tank facilities and at Port Castelló.

Article 

Andrea Pino, Alejandro Solís, Max Puig, Sergio Balaguer, Rosario Vidal, Pedro J. Sanz, Raúl Marín. UJIFISH-I: A modular and bioinspired robotic fish for inspection, hybrid teleoperation and sensor deployment in aquaculture, Ocean Engineering, Volume 354, Part 2, 2026, 124917, ISSN 0029-8018, https://doi.org/10.1016/j.oceaneng.2026.124917.

https://www.sciencedirect.com/science/article/pii/S0029801826007511

 

Scientists explore whether plastic particles could be linked to significant rises in liver disease




University of Plymouth





There is considerable evidence that microplastics and nanoplastics are present in the livers of humans, and wild animal populations on land and in the ocean.

Now experts in environmental and human health are investigating whether the presence of these tiny plastic particles in the liver is driving disease and directly contributing to the soaring global rates of liver disease.

Published in the journal Nature Reviews Gastroenterology & Hepatology, the article has been produced by researchers from the University of Plymouth’s newly-established Centre of Environmental Hepatology.

Through a wide-ranging review of existing studies, they say there is clear evidence that exposure to micro- and nanoplastics can trigger oxidative stress, fibrogenesis and inflammation in animals, features that resemble those of advanced liver disease in humans.

With the liver acting as the body’s first major firewall, processing and detoxifying everything humans consume, there is a clear potential for these particles to enable the transporting of microbial pathogens, antimicrobial resistance determinants, endocrine-disrupting chemicals, and carcinogenic additives into the human system.

The scientists have used that to introduce the concept of plastic-induced liver injury, and to call for increased research into whether it can accelerate the progression of alcohol-related liver disease and metabolic dysfunction associated steatotic liver disease, which affects more than 1 in 3 people worldwide.

The article’s lead author is Professor Shilpa Chokshi, Professor of Experimental Hepatology and Director of Centre of Environmental Hepatology, who has been driving research to develop therapeutics for chronic liver disease for more than two decades.

Professor Chokshi said: “Liver disease is rising globally and is now responsible for 1 in 25 deaths worldwide. While established risk factors such as obesity and harmful alcohol use remain central, they do not fully explain the scale or pace of this increase. This has led us to consider additional environmental factors, including micro- and nanoplastics, which may interact with existing disease processes and amplify liver injury. There is already strong evidence that plastics can accumulate and cause harm in the livers of animals, raising an important question – why should humans be any different?”

In the review, the researchers have highlighted critical methodological bottlenecks, key knowledge gaps and unmet research priorities, as well as a number of technical challenges that are presently hindering the search for further evidence of plastic-induced liver injury.

They have also provided a detailed assessment of the priority research required to fully quantify the effects of microplastics and nanoplastics on the liver, and the emphasised the importance of health and environmental experts working in tandem to address that.

Professor Chokshi added: “What this article shows is that we now have a growing body of evidence that plastics can accumulate in human tissues, and have been implicated in a range of medical conditions. From my perspective, having spent over two decades developing therapeutics for liver disease, the liver acts as the body’s gatekeeper – processing and detoxifying what we are exposed to. In an increasingly plastic-laden world, where plastics are closely associated with our food, water and air, these exposures may not only reach the liver but also interact with existing disease processes and amplify harm. If this is the case, it is something we need to investigate in much greater detail.”

Professor Richard Thompson OBE FRS, Professor of Marine Biology at the University of Plymouth, is another of the article’s co-authors. He is Head of the International Marine Litter Research Unit at the University of Plymouth and a co-coordinator of the Scientists’ Coalition for an Effective Plastics Treaty, and has spent the past three decades examining the sources and effects of microplastics and calling for a global consensus to prevent their future production.

“This is further evidence that plastic pollution is, without question, a global environmental and health challenge,” he said. “While some uncertainties about the absolute level of harm to the human liver remain, the fact that plastics are present at all – and the wider evidence of harm caused by plastic pollution – necessitates urgent action. The solutions unquestionably lie in ensuring the plastic products we make bring essential benefit to society and that those essential plastic products are safer – for example, in terms of their chemical composition – and far more sustainable, shedding fewer micro- and nanoparticles than is currently the case.”

Identifying the harm plastics may cause to the liver

Environmental hepatology is a rapidly emerging discipline that examines how the environments we live in – our air, water, soil, diet, and consumer products – influence liver health across the lifespan.

The Centre of Environmental Hepatology (CEH) brings together scientists, clinicians and environmental researchers to generate evidence that can inform prevention, improve patient outcomes, and support policies that reduce harmful exposures.

Among its projects are an ongoing investigation into how plastics and their associated chemicals, alcohol and dietary lipids interact to injure the liver and accelerate the progression of disease.

Using human liver samples, it will define the cellular and molecular events triggered by plastic exposure under healthy and disease relevant conditions and examine how plastics alter hepatocyte function, disrupt the gut barrier, activate inflammation and promote fibrosis.

Read more about the Centre of Environmental Hepatology.