Saturday, June 06, 2026

 

An exploration study on the relationship between chronological and perceived age in Chinese women with systematic validation of a new method for perceived age determination





Journal of Dermatologic Science and Cosmetic Technology

Graphical Abstract 

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An exploration study on the relationship between chronological and perceived age in Chinese women with systematic validation of a new method for perceived age determination

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Credit: This infographic is free to use in connection with this story if credited to "Beiersdorf Innovation Center Shangha"




This study enrolled 308 Chinese women aged 15–65 years to explore the relationship between chronological age, perceived age, and facial aging manifestations. Participants underwent expert assessment of aging features, standardized facial image acquisition, and perceived-age evaluation based on photographs by non-expert assessors. The study further collected information on the facial characteristics and regions influencing age perception and grouped participants according to the difference between perceived and chronological age. Results showed that Chinese women were perceived to be, on average, 1.6 years older than their actual age. Visible aging features showed strong correlations with perceived age, similar to their associations with chronological age. Nasolabial folds, marionette folds, facial contour tightness, skin evenness, and radiance emerged as major determinants of age perception. The study also identified age-specific patterns of aging features, supporting the use of perceived age as a practical endpoint for evaluating anti-aging products and designing targeted skincare strategies.

 

Technology used to monitor conservation efforts at Rome's Colosseum will be used at the Ipiranga Museum



The project, which was presented during FAPESP Week London, will use 3D laser scanning to create a digital model of the renovated building and establish an information management system for preventive maintenance.



Fundação de Amparo à Pesquisa do Estado de São Paulo

Technology used to monitor conservation efforts at Rome's Colosseum will be used at the Ipiranga Museum 

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FAU-USP professor Beatriz Kuhl: “Depending on how the scanning is done, there can be many inaccuracies. If it’s very well planned with a high degree of consistency, it yields precise results.” 

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Credit: Elton Alisson/Agência FAPESP





The same three-dimensional laser scanning technology used to monitor the Colosseum in Rome, Italy will be used in a conservation project at the Ipiranga Museum in São Paulo, Brazil. Beatriz Kuhl, a professor at the University of São Paulo’s Faculty of Architecture and Urbanism (FAU-USP), presented the initiative, which is scheduled to begin in July, during FAPESP Week London, held June 2–4 in the British capital.

The project involves a complete scan of the museum, inside and out. The goal is to analyze the behavior of the building following the restoration work carried out in recent years, establish a monitoring system, and, most importantly, create an information management model for preventive conservation purposes based on the HBIM (Historic Building Information Modeling) methodology. HBIM is a 3D modeling process for historic buildings and sites that reproduces all the physical and functional characteristics of the structure within a three-dimensional digital simulation. It integrates technologies, processes, data, people, and the history of the building.

“The idea is to feed an HBIM system with data from a specific area of the museum and then manage information about its conservation processes," Kuhl explained to Agência FAPESP.

Built between 1885 and 1890, the museum spent a decade closed to the public and resumed activities in September 2022 (read more at: agencia.fapesp.br/39578).

The DIAPReM laboratory at the University of Ferrara in Italy will carry out the technical execution of the scanning. This is the same team that recently completed the scanning of the Colosseum. The partnership between the Italian group, FAU-USP researchers, and the Center for Cultural Preservation at USP (CPC-USP) has existed for several years. The same team scanned the FAU-USP building, which was designed by Vilanova Artigas. They are now returning to the Ipiranga Museum to document the condition of the monument following restoration.

The continuity of the partnership is strategic. “To have truly comparable data, it’s essential to use the same methodology and reference points,” Kuhl stated. “Depending on how the scanning is done, there can be many inaccuracies. If it’s very well planned with a high degree of consistency, it yields precise results.”

Periodic scanning

A shoe box-sized, portable equipment emits laser beams that map the geometric coordinates of every point on the interior and exterior surfaces of the building with millimeter precision. In addition to geometry, the scanner captures reflectance data, which is the percentage of emitted light that returns to the sensor. This percentage varies depending on the material encountered, its moisture content, or the presence of mold.

This variation allows anomalies to be identified. “When we detect a point that differs from its neighbor and should be identical, we can ask whether that indicates some pathological condition,” Kuhl explained. The resulting data form a dense point cloud that serves as both a geometric record of the building and a means of diagnosing structural and conservation issues.

The scanning will be performed periodically without interfering with the operations of the museum. “A scanner will operate inside and outside the museum from time to time. The museum will absolutely not be closed, nor will its routine be altered,” the researcher assured.

Preventive conservation

The Ipiranga Museum project is part of a broader line of research that Kuhl has been developing for years at FAU-USP. This research focuses on preventive conservation, which aims to anticipate and avoid problems before they require costly and invasive interventions.

A previous project, funded by the Getty Foundation as part of the Keeping It Modern program, investigated the state of conservation of the FAU-USP building. The project generated recommendations that influenced specific renovations, such as a new roof waterproofing system and an access ramp to the building. However, Kuhl acknowledges that changing the culture of public heritage maintenance remains challenging.

“We’re still unable to act preventively because there’s a large backlog to address,” she admitted. “But this new research aims precisely to achieve that goal: to anticipate and avoid more invasive interventions.”

Kuhl believes that the Brazilian experience can benefit from established international references, such as the Casa de Rui Barbosa in Rio de Janeiro, where a systematic policy of preventive conservation was successfully implemented in the first two decades of this century.

On the theoretical side, the professor’s research group will engage in critical reflection on advanced diagnostic methods and their relationship with conceptual issues in conservation and the development of conservation plans. “These are two things that create tension and help us see problems in a different light,” she concluded.


Technology used to monitor conservation efforts at Rome's Colosseum will be used at the Ipiranga Museum 

Ipiranga Museum's integrated digital model: project starting in July will perform the full scanning on the interior and the exterior of the historic building

Credit

Ipiranga Digital

More information about FAPESP Week London is available at fapesp.br/week/2026/london.

About São Paulo Research Foundation (FAPESP)
The São Paulo Research Foundation (FAPESP) is a public institution with the mission of supporting scientific research in all fields of knowledge by awarding scholarships, fellowships and grants to investigators linked with higher education and research institutions in the State of São Paulo, Brazil. FAPESP is aware that the very best research can only be done by working with the best researchers internationally. Therefore, it has established partnerships with funding agencies, higher education, private companies, and research organizations in other countries known for the quality of their research and has been encouraging scientists funded by its grants to further develop their international collaboration. You can learn more about FAPESP at www.fapesp.br/en and visit FAPESP news agency at www.agencia.fapesp.br/en to keep updated with the latest scientific breakthroughs FAPESP helps achieve through its many programs, awards and research centers. You may also subscribe to FAPESP news agency at http://agencia.fapesp.br/subscribe

WORD OF THE DAY (WOTD)

The role of insects in the diet of our ancestors revealed


A study by the Institute of Evolutionary Biology (IBE: CSIC-UPF) sheds light on the history of entomophagy in human populations




Spanish National Research Council (CSIC)

Mealworm beetles (Tenebrio molitor) preserved in the entomological collection of Ehime University, Japan 

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Mealworm beetles (Tenebrio molitor) preserved in the entomological collection of Ehime University, Japan

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Credit: Juan Manuel Calvo Martin





In recent years, human population growth, coupled with the climate crisis, environmental pressures, and current production and consumption patterns, has driven the search for alternative food sources. With 1,611 insect species listed as edible, organizations such as the Food and Agriculture Organization of the United Nations (FAO) have proposed insects as a sustainable food source. However, despite the fact that hundreds of millions of people already consume them, Western societies continue to show aversion to entomophagy. While this rejection may have a cultural basis, its origin remains unknown.

To explore its roots, a study by the Institute of Evolutionary Biology (IBE), a joint centre of the Spanish National Research Council (CSIC) and Pompeu Fabra University (UPF), has used genomic analyses to reconstruct insect consumption over the past thousands of years. The research, published in Science Advances, suggests that insect consumption was sporadic and accidental in Europe, Central and East Asia, while it would have been more frequent in tropical regions and among Neanderthal populations. The results shed light on human evolution, ecology, and current insect consumption.

Genomic analysis reconstructs the history of entomophagy in Eurasia

To find evidence of insect consumption, the IBE team analyzed 745 samples of dental calculus (tartar) from anatomically modern humans, dating back up to 33,000 years. Tartar preserves traces of DNA from the species regularly consumed in the diet. The dental analyses suggest that modern humans in northern Eurasia did not routinely practice entomophagy. The team also studied the human genes involved in the digestion of chitin, a component of the insect exoskeleton. In North Eurasian human populations, chitinase genes carry mutations that confer a reduced capacity to digest insect exoskeletons, a trait that has persisted for the last 9,000 years, since the advent of agriculture.

“The scarce presence of insects in the diet of northern Eurasians suggests that the absence of entomophagy is not solely due to recent cultural factors, but also to a long ecological and evolutionary history”, says Pablo Librado, principal investigator at the IBE who led the study.

Neanderthals may have consumed insects more frequently

Despite inhabiting the same environment, Neanderthals had a greater abundance of insect DNA in their dental calculus than anatomically modern humans. These levels in Neanderthals are comparable to those found in western chimpanzees, which rely on entomophagy to supplement their diet on the savanna, especially during periods of drought.

The most abundant DNA remains in Neanderthal tartar belong to Diptera, the insect group that includes flies and mosquitoes, with the latter being particularly prominent. These findings support a recent hypothesis about the regular consumption of animal carcasses infested with fly larvae. The abundance of mosquito remains reinforces the possibility that the carcasses of their prey were kept in ponds and marshy areas, where mosquitoes lay their eggs.

The study also revealed that Neanderthal chitinase genes facilitate better digestion of insects, as also observed in the only Denisovan specimen analyzed.

The genetic imprint of entomophagy persists in tropical populations

The team analyzed genes linked to the digestion of insect exoskeleton chitin. These genes are expressed in the stomach and encode the enzymes chitinase acid (CHIA) and chitobiase (CTBS). In both ancient and modern samples, the researchers identified genetic variants associated with a greater expression of these enzymes in populations inhabiting areas near the tropics.

“Large quantities of insects need to be ingested to compensate for the high caloric expenditure involved in their collection. In the tropics, there is a greater availability of social insects, such as termites and locusts: their biomass and diversity allow for sustainable exploitation throughout the year, which even contributes to pest control”, explains Manuel Piñero, a predoctoral researcher at the IBE and first author of the study.

The expression of these enzymes gradually decreased as populations moved towards higher latitudes. This latitudinal genetic variation, maintained for at least 9,000 years, reflects the abandonment of entomophagy in European populations.

The future of entomophagy in Europe

“Beyond cultural or religious factors, our results suggest that the reduced availability of insects in non-tropical areas may have been a key factor in the abandonment of entomophagy, leading to a reduced capacity to digest insect exoskeletons”, Librado comments.

However, modern industrial processing allows us to take advantage of the nutritional properties of the food source without needing to digest this component, in addition to allowing its mass production in edible insect farms.

The Ancient Population Genomics research group led by Pablo Librado at the IBE studies the domestication process, using insect species recently approved for human consumption as a model and by comparing the genomes of farmed insects with the genomes of pre-domestication individuals extracted from entomological collections. “We investigate the evolution of domestication in animals, which also gives us information to improve the exploitation of insects for consumption, both as animal feed and for human consumption”, Librado concludes.

CSIC Comunicación

comunicacion@csic.es 

 

More people with disabilities are seeking work in the US  


nTIDE June 2026 Jobs Report



Kessler Foundation

nTIDE Month-to-Month Comparison of Labor Market Indicators for People with and without Disabilities 

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From April 2026 to May 2026, the employment-to-population ratio decreased from 37.9 to 37.8 percent for people with disabilities and increased from 74.9 to 75.0 percent for people without disabilities. The labor force participation rate increased from 41.1 to 42.0 percent for people with disabilities and increased from 77.9 to 78.0 percent for people without disabilities.

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Credit: Kessler Foundation





The June 2026 National Trends in Disability Employment (nTIDE) report reveals a large increase in job seeking among people with disabilities, signaling that more individuals are entering the labor force as economic pressure intensifies. This finding aligns with last month’s nTIDE forecast that rising prices would push more people with disabilities to seek employment, while progress in employment access continues.

Issued monthly by Kessler Foundation and the University of New Hampshire’s Institute on Disability, nTIDE tracks how broader economic conditions affect employment trends for people with and without disabilities.

Based on data from today’s BLS Jobs Report and separate nTIDE analysis, the employment-to-population ratio for people with disabilities (ages 16-64) decreased slightly from 37.9 percent in April 2026 to 37.8 percent in May 2026 (down 0.3 percent or 0.1 percentage points). For people without disabilities (ages 16-64), the employment-to-population ratio increased from 74.9 percent in April 2026 to 75.0 percent in May 2026 (up 0.1 percent or 0.1 percentage points). The employment-to-population ratio, a key indicator, is the percentage of people who are working relative to the total population (the number of people working divided by the total population, then multiplied by 100).

In contrast, the labor force participation rate for people with disabilities increased from 41.1 percent in April 2026 to 42.0 percent in May 2026 (up 2.2 percent or 0.9 percentage points). For people without disabilities, the labor force participation rate increased from 77.9 percent in April 2026 to 78.0 percent in May 2026 (up 0.1 percent or 0.1 percentage points). The labor force participation rate reflects the percentage of people who are in the labor force (working, on temporary layoff, on furlough, or actively looking for work in the last four weeks) relative to the total population (the number of people in the labor force divided by the number of people in the total population multiplied by 100).

“The labor force participation rate increased substantially while the employment-to-population ratio decreased slightly for people with disabilities. Taken together, these data suggest that more people with disabilities are entering the labor force and actively looking for work,” said Andrew Houtenville, PhD, professor of economics and director of the UNH-IOD. “This pattern is consistent with what we expect during inflationary periods, when people seek work to help offset rising prices and cover basic needs for themselves and their families. According to the most recent Annual Report on People with Disabilities in America, people with disabilities are more than twice as likely to live in families with incomes below the poverty line, making higher costs even more perilous for these households.”

Compared with the same time last year, the employment-to-population ratio for people with disabilities   decreased from 38.0 percent in May 2025 to 37.8 percent in May 2026 (down 0.5 percent or 0.2 percentage points). For people without disabilities, the employment-to-population ratio increased from 74.8 percent in May 2025 to 75.0 percent in May 2026 (up 0.3 percent or 0.2 percentage points).

The labor force participation rate for people with disabilities (ages 16-64) increased from 41.4 percent in May 2025 to 42.0 percent in May 2026 (up 1.4 percent or 0.6 percentage points). For people without disabilities (ages 16-64), the labor force participation rate also increased from 77.8 percent in May 2025 to 78.0 percent in May 2026 (up 0.3 percent or 0.2 percentage points).

In May, among workers ages 16-64, the 6,484,000 workers with disabilities represented 4.3 percent of the total 151,316,000 workers in the U.S.

Ask Questions about Disability and Employment
On the same day nTIDE is issued, the team hosts an nTIDE Lunch and Learn webinar. This live Zoom broadcast gives attendees a chance to ask questions about the latest findings, hear news and updates from the field, and learn from invited panelists who discuss current disability-related research and events.

On June 5, 2026, guest presenters Vicki Phillips, Mental Health Association in Atlantic County, and Donald Campbell, Atlantic Center for Independent Living, Principal at Unlock Access, joins Dr. Houtenville, and Shoshana Marin, Policy Fellow at the Association of University Centers on Disabilities. Visit the nTIDE archives at ResearchonDisability.org/nTIDE to see a recording of this nTIDE Lunch and Learn episode.

About National Trends in Disability Employment (nTIDE)
nTIDE is a joint effort of Kessler Foundation and the University of New Hampshire’s Institute on Disability. The nTIDE team tracks employment trends for people with and without disabilities, issuing monthly reports that reflect the impact of economic changes on the workforce. These reports use data from the U.S. Bureau of Labor Statistics but are customized by UNH-IOD to focus on working-age adults (ages 16 to 64). nTIDE is funded by the National Institute on Disability, Independent Living and Rehabilitation Research (NIDILRR; 90RTGE0005) and Kessler Foundation.

About the Institute on Disability at the University of New Hampshire
The Institute on Disability at the University of New Hampshire, founded in 1987, seeks to expand access and opportunity for people with disabilities in ways that strengthen communities locally and nationally. As part of a Carnegie Classification R1 university, the IOD accelerates disability inclusion through research, education, and collaboration. Its Center for Research on Disability delivers trusted analysis and tools that make disability data more accessible and actionable.

About Kessler Foundation
Kessler Foundation, founded in 1985, is a New Jersey-based nonprofit and global leader in rehabilitation research committed to changing the lives of people with disabilities. By conducting groundbreaking research, Kessler Foundation advances recovery and fosters independence to build a more inclusive and accessible world.

Our team of award-winning scientists develop and test novel interventions to transform care and optimize mobility, cognition, and quality of life for people with traumatic brain injury, spinal cord injury, stroke, multiple sclerosis, autism, and other neurological and developmental disabilities. By analyzing community and workforce participation, developing evidence-based solutions, and funding impactful community initiatives that expand employment opportunities, Kessler Foundation also addresses barriers to inclusion for people with disabilities.

Powered by a dedicated team of over 175 professionals funded by federal and state grants and private philanthropy, Kessler Foundation is redefining what is possible in rehabilitation care and recovery. For more information, visit kesslerfoundation.org.

 

Climate change and wine grapes: Go, stay or change?




Cornell University





ITHACA, N.Y. – When temperatures climb above 100 degrees Fahrenheit, grape clusters can heat to nearly 140 degrees in direct sunlight. The berries shrivel. Their color compounds break down. Yields drop. And for growers who have invested millions in land and vines expected to produce for decades, a single brutal heat wave can ripple through the balance sheet for years.

Climate change is making those calculations harder. Around the world, wine regions are confronting the same question: How do you keep making great wine when the climate that once defined your “terroir” is shifting?

A new interdisciplinary study by Cornell researchers tries to answer that question not just with agronomy, but with economics. Should growers keep growing the grapes they’ve historically grown, aided by new technologies? Or should they move their growing to cooler climes? Or maybe pivot to more heat- and drought-resistant grape varieties? 

The researchers’ conclusion: It depends. The smartest strategy hinges on how extreme the future climate becomes – and how willing wine drinkers are to embrace change.

Bradley Rickard, professor of food and agricultural economics; Alex Susskind, professor of wine education and management; and Justine E. Vanden Heuvel, professor of horticulture, collaborated to examine three strategies wine grape growers might use to cope with rising heat: shielding grapes from the sun with shade cloth, switching to more heat-tolerant grape varieties, or moving vineyards to cooler regions.

“Wine grapes are unique in that people are very attached to certain cultivars and the sense of the place where they come from,” Vanden Heuvel said. “That’s not true with most other crops. Do you care where your radish comes from?” 

Global temperatures have already risen more than 1 degree Celsius since preindustrial times, and vineyards are feeling the effects. Grapevines are sensitive to temperature at several stages of growth. At around 86 degrees Fahrenheit, photosynthesis begins to falter. Around 95 degrees Fahrenheit, compounds that give red wine its color start to degrade. Above 104, cells can suffer outright damage.

For iconic grapes like cabernet sauvignon, prolonged heat waves can shrink harvests and alter flavor.

That’s a particularly thorny problem in prestigious regions like Napa County, where cabernet commands some of the highest grape prices in the world. Consumers want to see it right on the label.

“Wine around the world has this tradition of having on the label the name of the grape and where it came from,” said Rickard. “Even inexpensive box and jug wine has the name of grape and place of origin on the front, and even among less-sophisticated consumers, there’s recognition of that. This paper is trying to understand if changing anything about that formula – whether the grape, the location or the production method – can affect what consumers are willing to pay.”

To understand the financial stakes, the researchers built a detailed economic model of a vineyard’s life cycle. Establishing a vineyard is expensive: planting vines, installing trellises and irrigation, and waiting years for the first full harvest. Once planted, a vineyard might produce grapes for 30 years.

The team calculated the long-term financial return of three climate-adaptation strategies.

The first option was technology: installing shade cloth above vines to block direct sunlight. Studies show this can lower grape temperatures by several degrees, reducing sunburn and protecting quality during heat waves. But it also adds substantial costs, Vanden Heuvel said, including installation and replacement every several years.

The second option was changing the grape itself. Instead of cabernet sauvignon, growers could plant varieties that tolerate hotter climates, such as carignane. These grapes often yield more fruit in hot conditions, though they may fetch lower prices.

The third option was migration. Rather than changing grapes, a grower might move production to a cooler nearby region such as Lake County, where temperatures historically run lower than in Napa.

Because wine markets depend heavily on consumer perception, the researchers also surveyed more than 300 American wine drinkers.

Participants were shown hypothetical wine labels reflecting the three strategies and asked how much they would be willing to pay.

The results were somewhat encouraging for growers experimenting with climate adaptations. When consumers were told that a wine used shade technology to protect grapes from extreme heat, they were willing to pay about 17% more on average. Wines made from a different grape variety received a roughly 12% premium when consumers learned the change helped vineyards adapt to climate stress. 

“It is safe to say that consumers are beginning to understand how climate change is affecting wine production,” Susskind said. “And they appear to be willing to pay a price premium as wine makers adjust to the new their normal.” 

Even wines produced in a new region received a modest boost in perceived value.

But those premiums were likely temporary. The researchers assumed they might last only a few years before fading as novelty wore off.

When the team ran the economic simulations, the “best” strategy shifted depending on how severe future heat waves became.

If climate change brings only mild temperature increases, sticking with traditional cabernet sauvignon in Napa remains the most profitable approach. Under moderate heat stress, however, installing shade cloth can pay off, protecting yields enough to justify the added cost. And in the most extreme scenarios, switching to a heat-tolerant grape variety produced the strongest financial return.

In other words, adaptation is not one decision but an evolving set of tradeoffs. The Cornell researchers say their framework could help vineyard owners evaluate those decisions with clearer financial expectations.

For additional information, see this Cornell Chronicle story.

 Cornell University has dedicated television and audio studios available for media interviews.

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