Tuesday, February 27, 2024

 

German scientists measuring cloud chemistry above Australia and Pacific in flying HALO laboratory

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A team of German scientists have been circling the skies above northern Australia and the Pacific Ocean in a high-tech research aircraft studying the atmospheric chemistry occurring above the clouds.

The Chemistry of the Atmosphere: Field Experiment (CAFE) team has tracked weather events and taken samples and measurements up to 15 kilometres above sea level.

Professor Mira Pöhlker from the Leibniz Institute for Tropospheric Research and Max Planck Institute for Chemistry said the team's research would help refine weather and climate models leading to better forecasts and projections.

woman in white and blue shirt
Professor Mira Pöhlker says CAFE-Pacific findings will help inform future climate predictions.(ABC Far North: Brendan Mounter)

"This really helps us to understand the [climate] systems better to better predict how it will change in the future," Professor Pöhlker said.

"To predict it, we really need to understand it."

The CAFE-Pacific mission is the third research project of its kind, with atmospheric studies undertaken in the skies over Africa and South America from 2018.

Southern skies 'exciting' to explore

The region offshore from Australia's north-east is of particular interest to the CAFE team for its high ocean temperature, which causes the strongest high-reaching convection in the world.

It produces columns of upward-rising warm air, which act as highways for heat, moisture, particulates, and gasses to be transported from the surface of the planet high into the atmosphere.

woman in dark shirt with trees in background
Dr Clara Nussbaumer says the southern hemisphere has unique atmospheric conditions.(ABC Far North: Brendan Mounter)

Dr Clara Nussbaumer, a postdoctoral researcher working on the project, said the tropics were an exciting place to explore as an atmospheric scientist.

"The combination of intense solar radiation, mixing due to convection, large regional differences in lightning activity, and contrasting tropical waters and the Australian continent, means there's everything you need for a lot of interesting atmospheric chemistry to occur," she said.

Regions in the southern hemisphere, including Australia and the Pacific, have been specifically chosen due to their remoteness.

group of people in high-vis vests walk from jet plane on tarmac
The team of German scientists disembark after measuring atmospheric conditions.(Supplied)

"It's the most similar to pre-industrial conditions, so for us, this is what really makes it interesting," Dr Nussbaumer said.

"We can sample the air and do some comparisons [to the northern hemisphere, which allows us] to make some projections on what it could look like with ongoing greenhouse gas emissions."

Professor Pöhlker said there were many more people in the northern hemisphere.

"If we want to understand how human beings influence all the processes, we need to get that contrast, which we're able to do here," she said.

Flying laboratory high in the sky

The researchers are conducting their studies in a state-of-the art research aircraft dubbed HALO (High Altitude and Long Range Research Aircraft).

The aircraft is a flying laboratory equipped with highly-sensitive instruments normally found in high-end chemistry laboratories.

Most of the instruments have been modified or custom-built.

jet plane with custom fitted scientific measuring equipment on nose sits on tarmac
The HALO is fitted with advanced instruments to measure atmospheric conditions.(Supplied)

Professor Pöhlker said the highly-modified Gulfstream G550 jet's long-range capabilities had assisted the scientific mission significantly.

"We can reach places 10,000 kilometres away. We can go very high, up to 15 kilometres in the atmosphere, and we can stay in the air for 12 hours, which gives us a lot of freedom to do really great research up in the air," she said.

"We can measure pressure, temperature, water vapour in the air with accuracy from the nose on the aircraft, which can get that information without any influence from the actual aircraft."

The CAFE-Pacific team clocked more than 150 hours flight time in the HALO during the two-month scientific mission travelling north from Cairns to Papua New Guinea and the equator, west across the Arafura Sea, and east across the Coral Sea.

We looked at 700 plant-based foods to see how healthy they really are. Here’s what we found

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 A burger in a bun with green avocado, green lettuce, red tomato and sauce and brown patty sits on a wooden chopping board
Plant-based food is easier to buy but is it as healthy as we hope?()

If you're thinking about buying plant-based foods, a trip to the supermarket can leave you bewildered.

There are plant-based burgers, sausages and mince. The fridges are loaded with non-dairy milk, cheese and yoghurt. Then there are the tins of beans and packets of tofu.

But how much is actually healthy?

Our nutritional audit of more than 700 plant-based foods for sale in Australian supermarkets has just been published.

We found some products are so high in salt or saturated fat, we'd struggle to call them "healthy".

We took (several) trips to the supermarket

In 2022, we visited two of each of four major supermarket retailers across Melbourne to collect information on the available range of plant-based alternatives to meat and dairy products.

We took pictures of the products and their nutrition labels.

We then analysed the nutrition information on the packaging of more than 700 of these products.

This included 236 meat substitutes, 169 legumes and pulses, 50 baked beans, 157 dairy milk substitutes, 52 cheese substitutes and 40 non-dairy yoghurts.

Plant-based meats were surprisingly salty

We found a wide range of plant-based meats for sale. So, it's not surprising we found large variations in their nutrition content.

Sodium, found in added salt and which contributes to high blood pressure, was our greatest concern.

The sodium content varied from 1 milligram per 100 grams in products such as tofu, to 2,000mg per 100g in items such as plant-based mince products.

This means we could eat our entire daily recommended sodium intake in just one bowl of plant-based mince.

An audit of 66 plant-based meat products in Australian supermarkets conducted in 2014 found sodium ranged from 316mg in legume-based products to 640mg in tofu products, per 100g. In a 2019 audit of 137 products, the range was up to 1,200mg per 100g.

In other words, the results of our audit seems to show a consistent trend of plant-based meats getting saltier.

Image of pink patties on a conveyer belt.
Plant-based foods are easier to buy but some hide high sodium levels.(ABC: Cam Lang)

What about plant-based milks?

Some 70 per cent of the plant-based milks we audited were fortified with calcium, a nutrient important for bone health.

This is good news as a 2019-2020 audit of 115 plant-based milks from Melbourne and Sydney found only 43 per cent of plant-based milks were fortified with calcium.

Of the fortified milks in our audit, almost three-quarters (73 per cent) contained the recommended amount of calcium – at least 100mg per 100mL.

We also looked at the saturated fat content of plant-based milks.

Coconut-based milks had on average up to six times higher saturated fat content than almond, oat or soy milks.

Previous audits also found coconut-based milks were much higher in saturated fat than all other categories of milks.

A first look at cheese and yoghurt alternatives

Our audit is the first study to identify the range of cheese and yoghurt alternatives available in Australian supermarkets.

Calcium was only labelled on a third of plant-based yoghurts, and only 20 per cent of supermarket options met the recommended 100mg of calcium per 100g.

For plant-based cheeses, most (92 per cent) were not fortified with calcium. Their sodium content varied from 390mg to 1,400mg per 100g, and saturated fat ranged from 0g to 28g per 100g.

So, what should we consider when shopping?

As a general principle, try to choose whole plant foods, such as unprocessed legumes, beans or tofu. These foods are packed with vitamins and minerals. They're also high in dietary fibre, which is good for your gut health and keeps you fuller for longer.

If opting for a processed plant-based food, here are five tips for choosing a healthier option.

1. Watch the sodium

Plant-based meat alternatives can be high in sodium, so look for products that have around 150-250mg sodium per 100g.

2. Pick canned beans and legumes

Canned chickpeas, lentils and beans can be healthy and low-cost additions to many meals. Where you can, choose canned varieties with no added salt, especially when buying baked beans.

3. Add herbs and spices to your tofu

Tofu can be a great alternative to meat. Check the label and pick the option with the highest calcium content. We found flavoured tofu was higher in salt and sugar content than minimally processed tofu. So it's best to pick an unflavoured option and add your own flavours with spices and herbs.

4. Check the calcium

When choosing a non-dairy alternative to milk, such as those made from soy, oat, or rice, check it is fortified with calcium. A good alternative to traditional dairy will have at least 100mg of calcium per 100g.

5. Watch for saturated fat

If looking for a lower saturated fat option, almond, soy, rice and oat varieties of milk and yoghurt alternatives have much lower saturated fat content than coconut options. Pick those with less than 3g per 100g.

Laura Marchese is a PhD student and Katherine Livingstone is a senior research fellow. Both work at Deakin University's Institute for Physical Activity and Nutrition. This piece first appeared on The Conversation.

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Pregnant women in South Africa should be offered social grants – it’ll save the state money in the long run

THE CONVERSATION
Published: February 24, 2024 

A baby’s first 1,000 days, from the time of conception until their second birthday, is a crucial window of opportunity to optimise their potential – through healthy nutrition for the mother during pregnancy, and then for the child after birth.

Undernutrition during this early period can cause stunting, which has major health and social effects later in life. Stunted children may never reach their full potential, and may suffer from obesity and related diseases for the rest of their lives. This costs the individual their health and their future, and costs governments billions in healthcare spending.

Many studies have shown that pregnancy support grants or vouchers improve women’s nutritional status and their ability to access and benefit from antenatal care. Globally, around 41% of mothers with newborns receive a maternity benefit of some kind. This rises to more than 80% in Europe and Central Asia, but drops to 16% in Africa.

Currently, pregnant women in South Africa receive no such benefits. The child support grant, which amounts to R510 (approximately $27) a month, is only paid after a child is born and has a birth certificate.

In South Africa, more than a quarter of children under five (27%) are stunted. Improving pregnant women’s nutritional status – and thus the health of their babies – should be high on the list of priorities for South African policymakers. It would contribute to ending childhood malnutrition, reducing poverty and unemployment and raising future generations of healthy, productive children who, as adults, will drive economic growth.

Read more: South Africa needs to change direction on maternal health to solve child malnutrition

As health economists we wanted to establish whether extending the child support grant to pregnancy would be cost effective for the South African government.

Our research found that it would decrease healthcare costs by R31,200 ($1,600) per baby over the first 1,000 days of life, largely as a consequence of mothers attending antenatal care more regularly and reduced neonatal complications.

Applied to the whole population, this would save the government about R14 billion (US$720 million) over the first 1,000 days of children’s lives.
Mothers in need

A large proportion of pregnancies in South Africa (69%) occur in impoverished households. Almost half of all pregnancies (46%) occur in female-headed households. More than one third (35%) of pregnant women run out of money to buy food, and one quarter of them (25%) experience hunger.

Given that 13 million children now receive the child social grant, the number of mothers potentially eligible for a pregnancy support grant is likely to be sizeable.

Read more: How hunger affects the mental health of pregnant mothers
Making healthy food choices

A 2021 pilot study by GrowGreat, an organisation dedicated to achieving zero stunting by 2030, gave 2,618 poor pregnant women in the Western Cape province a R300 ($15.40) digital food voucher every two weeks for 16 weeks and showed that the women used the grant money to buy nutritious foods.

The pilot also highlighted the grant’s psychological benefits. Having the power to make healthier food choices for themselves and their unborn babies not only relieved their financial burden but also gave them hope for the future.

Policy on a pregnancy support grant

A pregnancy support grant has already been proposed by the SA Law Reform Commission and would prioritise support for the most impoverished and vulnerable people.

Some people argue that the child support grant encourages women to get pregnant. Numerous studies have shown that this is not the case. In fact, many women with children who need the grant do not access it – especially teenagers.

Across the globe low- and middle-income countries, such as India, Bangladesh, Mexico, Nepal, Nigeria, Kenya and Brazil, have tried to address the financial burden placed on pregnant women by providing them with pregnancy support grants. These studies found that such grants promote weight gain during pregnancy, reduce maternal anaemia, increase access to services during pregnancy and childbirth, reduce maternal mortality, and prevent low-birthweight births and infant mortality.

Read more: Maternal malnutrition affects future generations. Kenya must break the cycle

Benefits of extending the child support grant into pregnancy have the potential to enhance the lives of families and communities as well as individual children and save the South African government billions. The knock-on effects in terms of hope, motivation, learning and employment of women – and thus for the economy – are likely to be immense.


Authors

Susan Goldstein
Associate Professor in the SAMRC Centre for Health Economics and Decision Science - PRICELESS SA (Priority Cost Effective Lessons in Systems Strengthening South Africa), University of the Witwatersrand
Susan Goldstein receives funding from NIHR, UKRI, and the SAMRC. She is on the board of the Southern African Alcohol Policy Alliance SA.
Aisha Moolla
Health economist, University of Sheffield
Aisha Moolla received funding from the UK's NIHR with additional support from the SAMRC/Wits Centre for Health Economics and Decision Science – PRICELESS SA
Partner





ELON MUSK’S NEURALINK HAS A SERIOUS ETHICAL PROBLEM, A NEUROSURGEON WARNS

Information about the brain chip implant remains scarce.


BYNANCY S. JECKER,ANDREW KOAND
THE CONVERSATION
FEB. 25, 2024
NurPhoto/Getty Images

Putting a computer inside someone’s brain used to feel like the edge of science fiction. Today, it’s a reality. Academic and commercial groups are testing “brain-computer interface” devices to enable people with disabilities to function more independently. Yet Elon Musk’s company, Neuralink, has put this technology front and center in debates about safety, ethics, and neuroscience.

In January 2024, Musk announced that Neuralink implanted its first chip in a human subject’s brain. The Conversation reached out to two scholars at the University of Washington School of Medicine – Nancy Jecker, a bioethicist, and Andrew Ko, a neurosurgeon who implants brain chip devices – for their thoughts on the ethics of this new horizon in neuroscience.

HOW DOES A BRAIN CHIP WORK?


A brain-computer interface system at the booth of Beijing Tiantan Hospital in 2023
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XINHUA NEWS AGENCY/XINHUA NEWS AGENCY/GETTY IMAGES

Neuralink’s coin-size device, called N1, is designed to enable patients to carry out actions just by concentrating on them without moving their bodies.

Subjects in the company’s PRIME study – short for Precise Robotically Implanted Brain-Computer Interface – undergo surgery to place the device in a part of the brain that controls movement. The chip records and processes the brain’s electrical activity and then transmits this data to an external device, such as a phone or computer.

The external device “decodes” the patient’s brain activity, learning to associate certain patterns with the patient’s goal: moving a computer cursor up a screen, for example. Over time, the software can recognize a pattern of neural firing that consistently occurs while the participant is imagining that task and then execute the task for the person.

Neuralink’s current trial is focused on helping people with paralyzed limbs control computers or smartphones. Brain-computer interfaces, commonly called BCIs, can also be used to control devices such as wheelchairs.

A FEW COMPANIES ARE TESTING BCIS. WHAT’S DIFFERENT ABOUT NEURALINK?


Musk at a French tech conference in 2023.
BLOOMBERG/GETTY IMAGES

Noninvasive devices positioned on the outside of a person’s head have been used in clinical trials for a long time, but they have not received approval from the Food and Drug Administration for commercial development.

There are other brain-computer devices, like Neuralink’s, that are fully implanted and wireless. However, the N1 implant combines more technologies in a single device: It can target individual neurons, record from thousands of sites in the brain.

NEURALINK


Neuralink received FDA approval for human trials in May 2023. Musk announced the company’s first human trial on his social media platform, X – formerly Twitter – in January 2024.

Information about the implant, however, is scarce, aside from a brochure aimed at recruiting trial subjects. Neuralink did not register at ClinicalTrials.gov, as is customary and required by some academic journals.

Some scientists are troubled by this lack of transparency. Sharing information about clinical trials is important because it helps other investigators learn about areas related to their research and can improve patient care. Academic journals can also be biased toward positive results, preventing researchers from learning from unsuccessful experiments.

Fellows at the Hastings Center, a bioethics think tank, have warned that Musk’s brand of “science by press release, while increasingly common, is not science.” They advise against relying on someone with a huge financial stake in a research outcome to function as the sole source of information.

When scientific research is funded by government agencies or philanthropic groups, its aim is to promote the public good. Neuralink, on the other hand, embodies a private equity model, which is becoming more common in science. Firms pooling funds from private investors to back science breakthroughs may strive to do good, but they also strive to maximize profits, which can conflict with patients’ best interests.

In 2022, the U.S. Department of Agriculture investigated animal cruelty at Neuralink, according to a Reuters report, after employees accused the company of rushing tests and botching procedures on test animals in a race for results. The agency’s inspection found no breaches, according to a letter from the USDA secretary to lawmakers, which Reuters reviewed. However, the secretary did note an “adverse surgical event” in 2019 that Neuralink had self-reported.

In a separate incident also reported by Reuters, the Department of Transportation fined Neuralink for violating rules about transporting hazardous materials, including flammable liquids.

WHAT OTHER ETHICAL ISSUES DOES NEURALINK’S TRIAL RAISE?



Neuralink is currently about the size of a large coin.
NEURALINK

When brain-computer interfaces are used to help patients who suffer from disabling conditions function more independently, such as by helping them communicate or move about, this can profoundly improve their quality of life. In particular, it helps people recover a sense of their own agency or autonomy – one of the key tenets of medical ethics.

However well-intentioned, medical interventions can produce unintended consequences. With BCIs, scientists and ethicists are particularly concerned about the potential for identity theft, password hacking, and blackmail. Given how the devices access users’ thoughts, there is also the possibility that their autonomy could be manipulated by third parties.

The ethics of medicine requires physicians to help patients while minimizing potential harm. In addition to errors and privacy risks, scientists worry about the potential adverse effects of a completely implanted device like Neuralink since device components are not easily replaced after implantation.

When considering any invasive medical intervention, patients, providers, and developers seek a balance between risk and benefit. At current levels of safety and reliability, the benefit of a permanent implant would have to be large to justify the uncertain risks.
WHAT’S NEXT?


Musk has said his ultimate goal is to help humanity “keep pace” with artificial intelligence.


For now, Neuralink’s trials are focused on patients with paralysis. Musk has said his ultimate goal for BCIs, however, is to help humanity – including healthy people – “keep pace” with artificial intelligence.

This raises questions about another core tenet of medical ethics: justice. Some types of supercharged brain-computer synthesis could exacerbate social inequalities if only wealthy citizens have access to enhancements.

What is more immediately concerning, however, is the possibility that the device could be increasingly shown to be helpful for people with disabilities but become unavailable due to loss of research funding. For patients whose access to a device is tied to a research study, the prospect of losing access after the study ends can be devastating. This raises thorny questions about whether it is ever ethical to provide early access to breakthrough medical interventions prior to their receiving full FDA approval.

Clear ethical and legal guidelines are needed to ensure the benefits that stem from scientific innovations like Neuralink’s brain chip are balanced against patient safety and societal good.

This article was originally published on The Conversation by Nancy S. Jecker and Andrew Ko at the University of Washington. Read the original article here.



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