Thursday, September 11, 2025

 

HKUST team develops AI-powered tool for accurate prediction of coastal oceans’ health



Hong Kong University of Science and Technology
Framework of the method 

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Framework of the method 

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Credit: HKUST






A research team from the Hong Kong University of Science and Technology (HKUST), led by Professors Gan Jianping (Department of Ocean Science) and Professor Yang Can (Department of Mathematics), has developed a novel AI-powered tool named STIMP for diagnosing coastal ocean productivity and ecosystem health. STIMP introduces a novel paradigm that imputes missing data and then predicts Chlorophyll-a (Chl-a) concentrations across large spatiotemporal scales. In tests across four representative global coastal regions, STIMP significantly outperformed existing geoscience tools, reducing the mean absolute error (MAE) for imputation by up to 81.39% and for prediction by 58.99%. Accurate Chl-a prediction aids in early detection of harmful algal blooms, ecosystem protection, and provides data-driven insights for evidence-based policy-making. 

 

Coastal oceans are the world’s most productive marine ecosystems because terrestrial nutrient input and active hydrodynamics produce high biological productivity and biodiversity. The ecosystems of coastal oceans, however, are vulnerable to frequent and severe eutrophication, biogeochemical extremes, and hypoxia that substantially threaten the sustainability of these coastal environments and the blue economies of the coastal zones. The concentration of Chl-a is a key indicator of the overall health of marine environments. Data-driven methods, utilizing remote sensing Chl-a data to achieve large-scale spatiotemporal diagnosis of ocean environmental quality, is a promising solution. However, there remain three challenges in developing large-scale spatiotemporal Chl-a data-driven prediction method. First, temporal variations are difficult to capture in existing data. Second, spatial heterogeneity and relationships are difficult to mode. Third, high rates of missing observations render spatiotemporal variations more challenging to comprehend.  

 

To solve the above challenges, the HKUST research team developed an advanced AI-powered spatiotemporal imputation and prediction (STIMP) model for predicting Chl-a in coastal ocean. STIMP decomposes the prediction of Chl-a into two sequential steps: 1) the imputation process, which reconstructs multiple potential complete spatiotemporal Chl-a distributions from partial observations, and 2) the prediction process, which accurately predicts Chl-a based on each reconstructed continuous and complete spatiotemporal Chl-a distribution. Using Rubin’s rules, the final Chl-a prediction is obtained by averaging the outcomes of multiple imputation and prediction processes. In this way, our STIMP method not only improves the overall predictive performance through accurate imputation of missing data but also provides confidence intervals to quantify the prediction uncertainties. 

 

STIMP enables spatiotemporal imputation. STIMP significantly reduced MAE by 45.90~81.39% compared to the data interpolating empirical orthogonal function (DINEOF) method from geoscience, and by 8.92–43.04% compared to the state-of-the-art AI methods in four representative global coastal oceans. The Pearson correlation coefficients (PCC) of the STIMP imputed data and ground truth data were greater than 0.90 even when the rate of missing data equalled 90%. With accurate imputation, STIMP offers spatiotemporal prediction, achieving MAE reductions of 58.99% over biogeophysical models and 6.54–13.68% over AI benchmarks. STIMP can be applied to global coastal oceans, offering a new approach for predicting oceans’ Chl-a that typically have spatiotemporally limited data.  

 

High-accuracy prediction of Chl-a concentration leads to significant benefits and solutions across various fields. In ecosystem management and conservation, it enables early detection of harmful algal blooms, allowing for proactive measures to protect aquaculture and coastal ecosystems. For policy and decision support, it provides data-driven insights for policymakers to design evidence-based fisheries regulations and pollution control measures. 

 

The research has been published in Nature Communications 

For more details, please refer to:Zhang, F., Kung, H., Zhang, F., Yang, C., & Gan, J. (2025). AI-powered spatiotemporal imputation and prediction of chlorophyll-a concentration in coastal ecosystems. Nature Communications, 16(1), 7656. https://doi.org/10.1038/s41467-025-62901-9  

New study calls for the rebirth of educational research in the age of AI



A recent article offers insights into challenges and opportunities for educational research in the AI era



Peer-Reviewed Publication

ECNU Review of Education





A groundbreaking article published in ECNU Review of Education argues that traditional educational research has reached a breaking point and must be reimagined in the era of artificial intelligence (AI). Titled The Death and Rebirth of Research in Education in the Age of AI: Problems and Promises, the article by University of Kansas scholars Yong Zhao, Neal Kingston, and Rick Ginsberg, identifies long-standing problems with educational research and outlines a vision for its rebirth in an AI-driven world.

Despite an estimated 140,000 educational research articles being published annually, the authors note that the field has had limited impact on policy and practice. They attribute this disconnect to several entrenched problems, such as flawed and biased peer review, quantification bias and misuse of statistics, entrenched “paradigm wars” between research methods, and overgeneralization across diverse contexts. In addition, the neglect of individual learner diversity, limited educational imagination, and a narrow focus on standardized outcomes further constrain the influence of educational research on real-world practice and policy.

With the rise of generative AI, these problems are magnified. The rapid evolution of AI tools destabilizes traditional assumptions of stable treatments, linear causalityand human-centered cognition, making much of today’s research obsolete before it can be published. At the same time, AI creates unprecedented opportunities for participatory, iterative, and systems-oriented research—but only if scholars embrace new epistemologies and methodologies.

“Educational research cannot simply optimize old methods for a new era. It must undergo an epistemological rebirth,” said co-author Yong Zhao. “AI challenges us to rethink not only how we do research, but also what education itself is for in a world where machines can outperform humans on many cognitive tasks.”

The article calls for a shift toward methodological pluralism, ethical vigilance, and epistemological innovation. It urges researchers to adopt design-based, complexity-informed, and futures-oriented approaches that account for human–AI collaboration, distributed cognition, and equity concerns.

This work contributes to the growing international debate about how education—and the research that guides it—must adapt in response to the accelerating disruptions of artificial intelligence.

***

Reference

DOI: https://doi.org/10.1177/20965311251367053  

 

Americans’ knowledge of civics increases, Annenberg survey finds



Survey also finds that most have little or no trust in Supreme Court as gap between parties widens





Annenberg Public Policy Center of the University of Pennsylvania

Knowledge of the Three Branches 

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APPC Constitution Day Survey 2024-2025

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Credit: Annenberg Public Policy Center






Americans are more knowledgeable this year in answering basic civics questions, according to the Annenberg Constitution Day Civics Survey, conducted annually by the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.

More than two-thirds of U.S. adults (70%) are able to name all three branches of government – the executive, judicial, and legislative – significantly more than a year ago (65%). When asked which rights the First Amendment guarantees, 79% can name “freedom of speech,” an increase over 2024 (74%).

“People can’t cherish, safeguard, or exercise their constitutionally protected rights unless they know that they have them and understand how effective use of them sustains our system of government,” said APPC director Kathleen Hall Jamieson. “Civics education at home and in schools should be a high priority as a result.” 

Released for Constitution Day (Sept. 17th), the nationally representative survey also finds that trust in the U.S. Supreme Court continues to deteriorate, with nearly 6 in 10 people (59%) voicing little or no trust the nation’s highest court is operating in their best interests.

Highlights

The 2025 Annenberg Constitution Day Civics Survey finds that:

  • Over two-thirds of Americans (70%) can name all three branches of government.
  • Asked what specific rights are guaranteed by the First Amendment, 79% say freedom of speech.
  • Four in 10 U.S. adults (41%) have at least a moderate amount of trust the Supreme Court is operating in their best interests. There is a nearly 60-point gap between the parties – 75% of Republicans have at least a moderate amount of trust in the court but just 18% of Democrats do.
  • There’s bipartisan support for several potential Supreme Court reforms, with over 80% favoring prohibiting justices from participating in cases in which they have “personal or financial interests.”

Annenberg Constitution Day Civics Survey

The nationally representative Annenberg Constitution Day Civics Survey, conducted for the Annenberg Public Policy Center by independent research company SSRS, draws on responses to Annenberg surveys of empaneled, nationally representative samples of U.S. adults during three periods. In March, respondents (n=1,363) were asked about attitudes toward the Supreme Court. In May-July, that same panel (n=1,334) was asked about proposed reforms to the court. In August, a different nationally representative panel (n=1,684) was asked about civics knowledge. All have a margin of sampling error of ± 3.5 percentage points at the 95% confidence level. For details, see the topline. See the full release online for additional information.

The branches of government and First Amendment

More than two-thirds of Americans (70%) can name all three branches of government, the highest in a few years. (The question has been asked since 2007 and annually since 2014, but a shift in survey methodology from phone to internet in 2023 means the recent figures are not directly comparable to the older ones.) In addition, 12% can name two branches, 6% can name one, and 13% cannot name any, no significant change from last year.

There is an upsurge in awareness of most of the five First Amendment rights, with 40% able to name most of the rights, up from 30% in 2024. When respondents are asked if they can name the specific rights guaranteed by the First Amendment:

  • Nearly 4 out of 5 (79%) say freedom of speech, up significantly from 74% in 2024;
  • Nearly half (48%) say freedom of religion, up from 39% in 2024;
  • 36% say right of assembly, up from 27% in 2024;
  • 34% say freedom of the press, statistically unchanged;
  • 12% say the right to petition, statistically unchanged.

The 2025 increases in knowledge, during the first year of the second Trump administration, parallel a 2018 increase during the first Trump administration. In both cases, a torrent of executive actions and the resulting judicial cases and actions by Congress produced a rush of political news.

Political party affiliation did not appear to play a role in the increase in civics knowledge.

Eroding trust in the Supreme Court

In the past few years, a number of surveys have shown declining trust in the Supreme Court and a widening gap between the political parties in views on the court. The Annenberg survey finds that from 2019 to March 2025, the percentage of U.S. adults holding at least a moderate amount of trust in the court dropped from 68% to 41%.

“Trust has fallen sharply and become polarized,” said University of Pennsylvania political science professor Matt Levendusky, who directs APPC’s Institutions of Democracy division. “Even after previous controversial decisions, like Bush v. Gore, trust in the court rebounded. But in the years since Dobbs [in 2022], it has continued to erode.”

The survey finds a widening, nearly 60-point gap between the parties on trust in the Supreme Court. As of March 2025, 75% of Republicans and Republican-leaning respondents have at least a moderate amount of trust, up from 69% in May 2024, while just 18% of Democrats and Democratic-leaning respondents do, down from 29% in May 2024.  

“The court was once held in high esteem by Democrats and Republicans alike, but that is no longer the case,” Levendusky said. “If the court is just another political actor, then it loses its special place in our political system, with worrying long-term implications.”

Broad popular support for some Supreme Court reforms

Asked about potential measures to reform the Supreme Court, most Americans favor prohibiting participation of justices in cases in which they have personal or financial conflicts (83%); creating a formal ethics code for justices (78%); mandatory retirement age (72%); and term limits (69%). Under half favor other proposals – allowing the public to vote to overturn Supreme Court rulings on controversial issues (44%) and increasing the size of the court (31%).

How partisanship affects views of court reform

Bipartisan majorities favor four potential reforms to the Supreme Court, though there are partisan differences in the extent to which they favor them. The top potential reform supported by members of both parties is prohibiting justices from participating in cases in which they have personal or financial interests, backed by 86% of Democrats and 83% of Republicans. Notably, most survey respondents in both parties do not favor increasing the number of justices on the Supreme Court, an idea proposed by some Democrats and backed by 44% of Democrats, 15% of Republicans, and 33% of independents. One proposal – allowing the public to vote to overturn Supreme Court decisions on controversial issues – is supported by half of Democrats (50%), but just 38% of Republicans and 45% of independents.

Constitution Day

APPC releases its annual civics survey in advance of Constitution Day, which celebrates the signing of the Constitution on Sept. 17, 1787. APPC’s initiatives to enhance civics education include Annenberg Classroom, which offers free resources for teaching the Constitution, and the Civics Renewal Network, a coalition of 46 nonpartisan, nonprofit organizations dedicated to improving civics education by providing free, high-quality resources for teachers. New resources include the collaborative Constitution Day Hub website and the Annenberg Classroom film “Balancing State and Federal Power: The Constitution’s Commerce Clause.”

“Strengthening the citizenry’s knowledge of the U.S. Constitution remains paramount for the long-term health of the nation’s democracy. This year’s APPC Constitution Day Civics Survey points to some clear knowledge gains, but there is also evidence indicating that there is more work to be done,” said R. Lance Holbert, director of APPC’s Leonore Annenberg Institute for Civics.

The Annenberg Constitution Day Civics Survey was developed under the leadership of Levendusky, Jamieson, Holbert, research analyst Shawn Patterson Jr. and APPC’s managing director of survey research, Ken Winneg.

The Annenberg Public Policy Center was established in 1993 to educate the public and policy makers about communication’s role in advancing public understanding of political, science, and health issues at the local, state, and federal levels.















 

Multifaceted benefits of ginseng and its extracts: a brief review of immunomodulation, quality of life improvement, and antitumor potential





Xia & He Publishing Inc.
The proposed immunomodulatory and antitumor mechanisms associated with ginseng and its bioactive constituents 

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Created with Figdraw. The downward arrow indicates a decrease in content. The solid arrow represents “direct action”, with a clear path of influence; the dashed arrow indicates “indirect action”, which involves going through a roundabout route and achieving the effect through other factors. IgG, immunoglobulin G; iNOS, inducible nitric oxide synthase; MMP, matrix metalloproteinase; NK, natural killer; NO, nitric oxide; Rg, ginsenoside-Rg; Rh, ginsenoside Rh.

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Credit: Tianqi Wang, Lin Tang





Ginseng has long been used in traditional medicine to replenish Qi and address deficiency syndromes, often manifesting as fatigue and immune compromise. Modern research is now elucidating the mechanisms behind these effects, focusing on ginseng’s immunomodulatory properties, ability to improve quality of life, and potential role in cancer therapy. This review aims to consolidate recent findings on these aspects, highlighting both the promises and limitations of ginseng as a scientifically supported therapeutic agent.

Immunomodulatory Effects of Ginseng
Ginseng’s immunomodulatory properties are primarily attributed to its active compounds, ginsenosides and polysaccharides. Ginsenosides Rg1 and Rb1 regulate cytokine production by inhibiting pro-inflammatory factors like TNF-α and IL-6 while promoting anti-inflammatory IL-10. This bidirectional modulation helps maintain immune homeostasis. Additionally, ginseng enhances natural killer (NK) cell activity via the TLR4/MyD88 pathway, increasing cytotoxicity by two- to threefold. Polysaccharides in ginseng, such as arabinogalactan, activate macrophage receptors and promote hematopoietic recovery, as evidenced by accelerated white blood cell regeneration in irradiated animal models.

Quality of Life Improvement
Ginseng significantly improves quality of life, particularly in individuals experiencing sub-health states—a condition characterized by chronic fatigue, cognitive decline, and emotional disturbances. A clinical study using Renshen Yuanqi (RSYQ) Drink, a ginseng extract, reported an 85% improvement in sub-health scores among young adults after 30 days. Key benefits included reduced fatigue, enhanced cognitive function, and improved mood. These effects align with ginseng’s traditional use in alleviating chronic fatigue and supporting mental well-being, likely mediated by ginsenosides with antidepressant and neuroprotective properties.

Antitumor Potential
While direct cytotoxic effects of ginseng on tumor cells are not fully established, ginsenosides show promise in inhibiting tumor growth and metastasis. For example, ginsenoside Rh2 suppresses the PI3K/AKT pathway in prostate cancer, reducing tumor proliferation and invasion. Other ginsenosides, such as Rg3 and Compound K, exhibit neuroprotective effects and ameliorate cancer-related fatigue by activating AMPK signaling. These mechanisms suggest ginseng’s potential as an adjunct therapy in oncology, though clinical evidence remains preliminary.

Safety Considerations
Despite its benefits, ginseng poses safety concerns, particularly at high doses or when combined with certain medications. Adverse effects include nervous system disturbances, gastrointestinal issues, and interactions with anticoagulants (e.g., warfarin) and beta-blockers (e.g., metoprolol). Ginsenosides may also inhibit liver enzymes like CYP3A4, potentiating drug toxicity. Concurrent use with other herbs, such as aconite, can lead to severe reactions. Therefore, careful dosing and monitoring are essential for safe integration into clinical practice.

Clinical Cases and Future Directions
A case study involving a 62-year-old female cancer patient demonstrated a significant reduction in sub-health scores after 30 days of RSYQ Drink intervention. Future research should focus on large-scale randomized controlled trials to validate these findings and explore ginseng’s synergistic effects with conventional therapies. Optimized assessment tools for sub-health and mechanistic studies on immunomodulation and antitumor pathways are also needed.

Conclusion
Ginseng and its extracts offer compelling benefits for immune support, quality of life enhancement, and potential antitumor applications. However, robust clinical evidence is still limited, and safety concerns necessitate cautious use. Future studies should prioritize high-quality trials to fully harness ginseng’s potential in integrative medicine.

 

Full text:

https://www.xiahepublishing.com/2835-6357/FIM-2025-00027

 

The study was recently published in the Future Integrative Medicine.

Future Integrative Medicine (FIM) is the official scientific journal of the Capital Medical University. It is a prominent new journal that promotes future innovation in medicine.It publishes both basic and clinical research, including but not limited to randomized controlled trials, intervention studies, cohort studies, observational studies, qualitative and mixed method studies, animal studies, and systematic reviews.

 

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