Tuesday, June 24, 2025

SPACE/COSMOS

Growing homes on Mars: Texas A&M research pioneers autonomous construction using synthetic lichens



New self-growing technology could revolutionize Martian architecture by using living biomaterials to 3D print structures — without human intervention.




Texas A&M University

Mars Construction 

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A synthetic habitat could be built with the help of a self-growing technology that harnesses local resources and microbes to autonomously form structures on the Red Planet.

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Credit: Texas A&M University





Inhabiting Mars has long been a futuristic fantasy fueled by science fiction. However, successful landings on our neighboring planet over the past half-century have made this seemingly far-fetched idea increasingly plausible.

But don’t start packing just yet. First, we must figure out how to build structures millions of miles from Earth. Sending rockets carrying massive payloads of construction materials into space isn’t practical or affordable. So, how can we use the resources already present on the Red Planet to build your dream home? 

Enter Texas A&M University’s Dr. Congrui Grace Jin with the possible answer.

Jin and her colleagues from the University of Nebraska-Lincoln have worked for years on bio-manufacturing engineered living materials and have developed a synthetic lichen system that can form building materials with no outside intervention. Their latest study, funded by the NASA Innovative Advanced Concepts program and recently published in the Journal of Manufacturing Science and Engineering, applies this research to the autonomous construction of structures on Mars, using the planet’s regolith, which includes dust, sand and rocks.

This advancement has the potential to revolutionize extraterrestrial construction by enabling structures to be built in the most demanding environments with restricted resources. 

“We can build a synthetic community by mimicking natural lichens,” explains Jin. “We’ve developed a way to build synthetic lichens to create biomaterials that glue Martian regolith particles into structures. Then, through 3D printing, a wide range of structures can be fabricated, such as buildings, houses and furniture.”

Others have researched a variety of methods for bonding Martian regolith particles, including magnesium-based, sulfur-based, and a geopolymer creation. Yet all the methods require significant human assistance and thus are not feasible with the obvious lack of manpower on Mars. 

Another approach has been microbe-mediated self-growing technology. Various designs have been developed, such as bacterial biomineralization to bind sand particles into masonry, ureolytic bacteria to promote the production of calcium carbonate to make bricks, and NASA’s exploration of the use of fungal mycelium as a bonding agent.

Although microbe-mediated self-growing technology is very promising, the current practices are not completely autonomous because the microbes being used are limited to a single species or strain, thus their survivability requires a continuous supply of nutrients, meaning outside intervention is needed. Again, the lack of manpower on Mars makes this challenging.

To solve this problem, Jin’s team has developed a completely autonomous self-growing technology by designing a synthetic community making use of the advantages of multiple species. This system eliminates the need for external nutrient supplies.

The design uses heterotrophic filamentous fungi as bonding material producers because they can promote large amounts of biominerals and survive harsh conditions much better than heterotrophic bacteria. These fungi are paired with photoautotrophic diazotrophic cyanobacteria to create the synthetic lichen system. 

How does it work? The diazotrophic cyanobacteria fix carbon dioxide and dinitrogen from the atmosphere and convert them into oxygen and organic nutrients to help the survival and growth of filamentous fungi and increase the concentration of carbonate ions by photosynthetic activities. The filamentous fungi bind metal ions onto fungal cell walls and serve as nucleation sites for biomineral production, as well as enhance the growth of cyanobacteria by providing them water, minerals, and carbon dioxide. Both components secrete biopolymers that enhance the adhesion and cohesion among Martian regolith and precipitated particles to create a consolidated body. 

The system grows with only Martian regolith simulant, air, light and an inorganic liquid medium. In other words, no manpower needed. 

“The potential of this self-growing technology in enabling long-term extraterrestrial exploration and colonization is significant,” states Jin.

The next step of the project, already underway, is the creation of regolith ink to print bio-structures using the 3D printing technique of direct ink writing. 

Jin is an assistant professor in the Mechanical and Manufacturing Engineering Technology program in the Department of Engineering Technology and Industrial Distribution at Texas A&M University. Her fellow researchers from the University of Nebraska-Lincoln are Dr. Richard Wilson, Nisha Rokaya and Erin Carr. Read about the team’s related research.

Funding for this research is administered by the Texas A&M Engineering Experiment Station (TEES), the official research agency for Texas A&M Engineering.

 

Handy ‘MasSpec Pen’ collection could help detect opioids from the skin




American Chemical Society
Handy ‘MasSpec Pen’ collection could help detect opioids from the skin 

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A pen-like tool collects molecules from the skin that can be screened for opioids.  

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Credit: William Clarke, Johns Hopkins University School of Medicine





Opioids like fentanyl, morphine and oxycodone are the drugs most linked to overdoses in the U.S. Typical screening methods for drug usage involve collection of blood, saliva or urine samples. Now, in ACS’ Analytical Chemistry, researchers demonstrate a pen-like tool that can quickly and non-invasively collect molecules from the skin’s surface to be screened for opioids with mass spectrometry.

After seeing Dr. [Livia] Eberlin’s fascinating work using the ‘MasSpec Pen’ on non-destructive sampling of tissues for cancer identification, I became very interested in investigating how this technology could be used for rapid, non-invasive toxicology screening in clinics and acute care settings,” says study coauthor William Clarke. “Access to this information in real time could allow for earlier intervention for patients at risk for drug overdose or in need of substance use treatment.”

A common analytical method for detecting opioids in blood, saliva and urine samples is liquid chromatography mass spectrometry (LCMS). Clinic-based LCMS screening offers excellent detection and sensitivity, but sample collection and preparation is complicated and time-consuming. In addition to body fluids, opioids are also distributed in the skin. So, William Clarke, Livia Eberlin and colleagues came together to modify their handheld MasSpec Pen into a modular tool that quickly collects molecules from the skin’s surface to be tested for opioids, eliminating the need for additional sample prep.

The new version of the MasSpec Pen delivers a small droplet of water and ethanol to the surface of the skin. While it sits there, the liquid extracts molecules that could indicate past drug use. After 3 seconds, the liquid droplet is sucked up by the pen into a collection vial. The sample can be immediately analyzed by electrospray ionization mass spectrometry or stored for future analysis.

After successful proof-of-concept demonstrations on patches of human skin, the team tested the MasSpec Pen on the arm or hand of eight participants with known exposure to fentanyl and hydromorphone. When the researchers compared the new collection tool’s skin sample data to traditionally collected urine and saliva data, they found:

  • Fentanyl in seven of the MasSpec Pen skin samples but no hydromorphone.
  • Fentanyl and hydromorphone in all eight urine samples.  
  • Fentanyl in five saliva samples (one sample could not be tested) and hydromorphone in four saliva samples.

Although the samples collected by the MasSpec Pen did not have the same level of detection as the urine and saliva samples, the device’s easy use and portability show promise for future development. The researchers note that discrepancies might stem from the time of drug ingestion relative to when the testing was performed. The team’s future studies may explore the impact of skin type, skin cleanliness and extent of drug exposure on the MasSpec Pen detection limits and analysis of opioids.

The authors acknowledge funding from the Eli Lilly Young Investigator Award, a Welch Research Grant and Thermo Fisher Scientific. The human skin samples used in this work were collected per the approved protocol from the Cooperative Human Tissue Network Institutional Review Board. The clinical study was conducted per the approved protocol from the Johns Hopkins University School of Medicine.

Some authors have patents on the MasSpec Pen and are involved in MS Pen Technologies, Inc., a company commercializing the technology.

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The American Chemical Society (ACS) is a nonprofit organization founded in 1876 and chartered by the U.S. Congress. ACS is committed to improving all lives through the transforming power of chemistry. Its mission is to advance scientific knowledge, empower a global community and champion scientific integrity, and its vision is a world built on science. The Society is a global leader in promoting excellence in science education and providing access to chemistry-related information and research through its multiple research solutions, peer-reviewed journals, scientific conferences, e-books and weekly news periodical Chemical & Engineering News. ACS journals are among the most cited, most trusted and most read within the scientific literature; however, ACS itself does not conduct chemical research. As a leader in scientific information solutions, its CAS division partners with global innovators to accelerate breakthroughs by curating, connecting and analyzing the world’s scientific knowledge. ACS’ main offices are in Washington, D.C., and Columbus, Ohio.

Registered journalists can subscribe to the ACS journalist news portal on EurekAlert! to access embargoed and public science press releases. For media inquiries, contact newsroom@acs.org.

Note: ACS does not conduct research but publishes and publicizes peer-reviewed scientific studies.

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LEGUME LEAGUE

More than 130 physicians urge federal government to prioritize beans, peas, lentils in next dietary guidelines



Physicians Committee for Responsible Medicine





WASHINGTON, D.C. — In a June 24, 2025, letter, 134 physicians urged the Department of Health and Human Services and the U.S. Department of Agriculture to ensure that the next Dietary Guidelines for Americans include science-backed recommendations to prioritize the consumption of beans, peas, and lentils as a protein source.  

“This key recommendation will help meet our shared goal of preventing and reducing chronic disease,” wrote the doctors, members of the Physicians Committee for Responsible Medicine, a national health advocacy group which includes 17,000 physicians.  

The 2025 Dietary Guidelines Advisory Committee recently recommended that the current federal nutrition guidelines be modified to move the “Beans, Peas, and Lentils Subgroup” from the “Vegetables Food Group” to the “Protein Foods Group.” The Advisory Committee also recommended reorganizing the “Protein Foods Subgroups” to list “Beans, Peas, and Lentils” first, then “Nuts, Seeds, and Soy Products,” over “Seafood,” and “Meats, Poultry, and Eggs.” 

“This reorganization would better emphasize the benefits of legumes and would more accurately classify these foods as a major protein source in many Americans’ diets,” the letter says. “Additionally, this recommended reorganization would better educate the public on the nutritional value of these foods and help dispel the myth that plant-based proteins are ‘incomplete’ or inadequate sources of protein.”

The letter likewise points out beans, peas, and lentils provide an abundance of fiber, which Americans are currently deficient in. They are whole foods, often produced and sourced from American farmers. Plant-based sources of protein like legumes have regularly been linked to a lower risk of death from cardiovascular disease and cancer, unlike red and processed meats, which are strongly associated with cardiovascular disease, diabetes, and certain cancers.

The Dietary Guidelines Advisory Committee is a group of nationally recognized nutrition and public health experts who were tasked with reviewing the current body of nutrition science on specific topics and questions as well as developing a Scientific Report, released in December 2024, that included its independent, science-based advice for HHS and USDA to consider when updating the Dietary Guidelines for Americans.

“The Dietary Guidelines Advisory Committee’s report put important and appropriate emphasis on beans and other plant-based foods,” said Neal Barnard, MD, FACC, president of the Physicians Committee. “Overwhelming evidence supports the role of these foods in supporting cardiovascular health, promoting a healthy body weight, and reducing the risk of type 2 diabetes, cancer, and other serious conditions. It is vital that the next Dietary Guidelines for Americans prioritize these nutritious sources of protein.”

The Dietary Guidelines Advisory Committee’s Scientific Report recommended emphasizing beans, peas, and lentils while reducing consumption of red and processed meats.

The Dietary Guidelines for Americans are revised every five years by HHS and the USDA. New guidelines are expected to be released this year.

Note to reporters: To arrange an interview with Dr. Barnard, please contact Kim Kilbride at 202-717-8665 or kkilbride@pcrm.org

 

Researchers develop ‘vegan meat’ based on sunflower flour


The ingredient, extracted from the plant’s seeds, is a good source of protein and has a neutral flavor and aroma, making it easy to use in food products



Fundação de Amparo à Pesquisa do Estado de São Paulo

Researchers develop ‘vegan meat’ based on sunflower flour 

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Researchers enriched the product with tomato powder, spices, and a mixture of fat sources made up of sunflower, olive, and linseed oils

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Credit: Unicamp





Researchers from the Institute of Food Technology (ITAL) and the University of Campinas (UNICAMP), both in the state of São Paulo, Brazil, in collaboration with scientists from the Fraunhofer IVV Institute in Germany, have developed a food product made from sunflower flour that can be used as a meat substitute.

The ingredient is obtained by extracting oil from the seeds of the plant. In order for it to be consumed by humans, the husks and phenolic compounds from the grains must be removed before processing. These substances give the flour a dark color and reduce its digestibility. 

The next step was to prepare two formulations of meat alternatives. The first incorporated flour from roasted grains, and the second used textured sunflower protein. Both were enriched with tomato powder, spices, and a mixture of sunflower, olive, and linseed oils.

The patties were shaped into mini-burgers and baked. They then underwent sensory and physicochemical evaluations. The analysis results showed that the textured protein version had superior consistency, as well as high levels of protein and health-boosting fats, such as monounsaturated fatty acids. Additionally, the textured protein option had a significant mineral content, particularly of iron, zinc, magnesium, and manganese at 49%, 68%, 95%, and 89% of the recommended daily intake, respectively.

The authors of the study, supported by FAPESP, decided to study sunflower meal because sunflower oil is widely used in Europe and sunflower cultivation is expanding in Brazil. Another advantage of the ingredient is that it is not genetically modified. 

Additionally, the plant’s flour is a promising source of protein, which is highly relevant given the growing consumer demand for sustainable, plant-based options.  

Maria Teresa Bertoldo Pacheco, a researcher at ITAL’s Center for Food Science and Quality and the last author of an article on the research published in the journal Food Research International, says, “It should also be noted that, after removing the husks and phenolic compounds, the flour has a very neutral taste and aroma, especially compared to the various vegetable proteins on the market.”

Pacheco also points out that the product has a favorable composition of essential amino acids. This is another factor that could lead to its incorporation into the food industry as a meat product substitute from a nutritional point of view. “From a functional-technological standpoint, processes that build fibrous proteins, such as extrusion, are needed to deliver a product with a more meat-like appearance and texture,” says Pacheco. 

“I think the study provided a lot of positive references, both for making full use of the cultivar and for encouraging the consumption and appreciation of the flour. The partnership with German researchers was also very important, thanks to the sharing of working techniques, the exchange of knowledge, and the exchange of students and researchers,” she adds. 

About São Paulo Research Foundation (FAPESP)
The São Paulo Research Foundation (FAPESP) is a public institution with the mission of supporting scientific research in all fields of knowledge by awarding scholarships, fellowships and grants to investigators linked with higher education and research institutions in the State of São Paulo, Brazil. FAPESP is aware that the very best research can only be done by working with the best researchers internationally. Therefore, it has established partnerships with funding agencies, higher education, private companies, and research organizations in other countries known for the quality of their research and has been encouraging scientists funded by its grants to further develop their international collaboration. You can learn more about FAPESP at www.fapesp.br/en and visit FAPESP news agency at www.agencia.fapesp.br/en to keep updated with the latest scientific breakthroughs FAPESP helps achieve through its many programs, awards and research centers. You may also subscribe to FAPESP news agency at http://agencia.fapesp.br/subscribe.